Further development of the clinical potential of H2 relaxin [ 2012 - 2014 ]

Research Grant

Researchers: Prof John Wade (Principal investigator) ,  A/Pr Richard Hughes ,  Dr Mohammed Hossain ,  Prof Ross Bathgate

Brief description The hormone relaxin mediates cardiovascular and kidney changes during pregnancy. These important functions have led to its current use in clinical trials for the treatment of acute heart failure, a condition affecting millions of patients worldwide. However, there is an urgent need for a longer lasting form of relaxin for prolonged treatment of patients. Our studies will focus on understanding the blood breakdown of the peptide to lead to the design of longer lasting relaxin analogues.

Funding Amount $AUD 651,768.53

Funding Scheme Project Grants

Notes Standard Project Grant