grant

Understanding sensitivity and resistance to BRAF inhibitors in melanoma [ 2011 - 2013 ]

Also known as: Understanding Inhibition of BRAF in Melanoma

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1002655]

Researchers: Prof Grant Mcarthur (Principal investigator) ,  A/Pr Antoni Ribas Prof Rodney Hicks

Brief description Recent clinical studies have shown that the most common mutation found in melanoma in the gene BRAF can be successfully targeted for treatment. However many patient relapse after early responses and the drug can also cause growth of some skin tumours. This proposal will investigate the reasons for these observations using molecular-imaging and study of tumour tissues and cell lines. This will lead to new insights and better treatments for melanoma and other cancers with BRAF gene mutations.

Funding Amount $AUD 484,746.01

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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