grant

Investigating the interface between host innate immune cells and a fungal pathogen [ 2011 - 2014 ]

Also known as: Investigating the interactions between host and pathogen

Funded by National Health and Medical Research Council
Managed by The University of Melbourne
Managed by University of Melbourne
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1006839]

Researchers: Prof Alex Andrianopoulos (Principal investigator) ,  Dr Kylie Boyce

Brief description Fungi which infect humans are a major health problem, especially for those with compromised immune systems (eg. AIDS, transplant and cancer patients). These fungi cause disease by evading the immune system whilst deriving nutrients for growth. Some fungi evade the immune system by residing within host cells; a hostile and nutrient poor environment. This project will study a pathway that we have shown is required for growth inside host cells. This knowledge will open new avenues for treatment.

Funding Amount $AUD 578,085.75

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Medical and Health Sciences | Medical Microbiology | Medical Microbiology Not Elsewhere Classified | acquired immunodeficiency syndrome (AIDS) | fungal genetics | fungal pathogens | immunocompromised | infectious diseases | microbial infections | molecular pathogenesis | mycoses | opportunistic infections |
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