grant

The role of BAFF, its receptor TACI and Toll-like receptors in Autoimmunity and Tolerance. [ 2011 - 2013 ]

Also known as: TACI, TLR and innate immunity

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1008520]

Researchers: Prof Fabienne Mackay (Principal investigator) ,  Prof Paul Hertzog

Brief description There are 2 types of immune cells, innate cells reacting broadly against microbial elements, and adaptive cells educated to remember pathogens and provide improved immune responses. Most treatments against lupus target the adaptive cells with mixed success. We have discovered a new mechanism driving lupus at the level of innate immunity. This proposal will identify molecular players driving this unappreciated form of lupus and validate new therapeutic targets.

Funding Amount $AUD 486,824.89

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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