Imaging the hepatitis C virus life cycle in real-time [ 2012 - 2015 ]

Research Grant

Researchers: A/Pr Michael Beard (Principal investigator) ,  A/Pr Stuart Turville ,  Dr Nicholas Eyre

Brief description Hepatitis C virus (HCV) is a serious viral pathogen that causes significant liver disease. This proposal plans to examine how two proteins from the HCV, core and NS5A, interact with host proteins and pathways to facilitate viral replication and release of HCV; two processes that are poorly understood. Specifically we will tag viral proteins to allow us to investigate the HCV life cycle in living cells and determine the role of core and NS5A in facilitating HCV replication. This proposal may uncover novel therapeutic strategies to combat HCV.

Funding Amount $AUD 477,504.03

Funding Scheme Project Grants

Notes Standard Project Grant