ROLE OF PURINES IN RENAL AND TRANSPLANT INJURY [ 2012 - 2015 ]

Research Grant

Researchers: Prof Stephen Alexander (Principal investigator) ,  Dr Yuan Min Wang ,  Prof Karen Dwyer

Brief description Acute injury can lead to chronic immune activation in both chronic kidney disease and in transplantation. We will study the role of a class of molecules, the purines, that are released by injury and lead to immune activation. We will focus on the molecular variations and pharmacological blockade of their receptors as potential treatments for kidney disease and transplant graft failure.

Funding Amount $AUD 581,079.52

Funding Scheme Project Grants

Notes Standard Project Grant