Dissecting apoptosis and IL-15 dependent homeostasis pathways of natural killer (NK) cells [ 2013 - 2015 ]

Research Grant

Researchers: A/Pr Nicholas Huntington (Principal investigator) ,  Dr Sebastian Carotta

Brief description We will investigate how the cytokine IL-15 regulates the homeostasis of natural killer (NK) cells. NK cells are critical for immune responses against invading viruses or bacteria or upon detection of transformed cells. NK cells are primed to attack infected or transformed cells and are rapidly activated by direct interaction or by soluble signals. Knowledge of how NK cells development and how their numbers and function are controlled is paramount to understanding infectious disease immunology and developing better immuno-therapies.

Funding Amount $AUD 423,809.90

Funding Scheme Project Grants

Notes New Investigator Grant