How Deletional and Non-Deletional Tolerance Mechanisms Integrate to Prevent Autoimmune Disease [ 2013 - 2015 ]

Research Grant

Researchers: A/Pr Daniel Gray (Principal investigator) ,  A/Pr Marco Herold ,  Dr Lorraine O'Reilly

Brief description The body produces millions of immune cells every day to fight infection. Some of these immune cells are defective and dangerous because they can cause autoimmune diseases, like Type I diabetes and multiple sclerosis. To defuse this risk, such immune cells are either caused to die or are inactivated to prevent autoimmunity. We propose to investigate how the processes of immune cell death and inactivation work in health and disease so we may harness these mechanisms to cure autoimmunity.

Funding Amount $AUD 509,944.93

Funding Scheme Project Grants

Notes Standard Project Grant