grant

Determining the mechanisms underlying chronic visceral pain and providing novel treatment strategies [ 2013 - 2016 ]

Also known as: Determining mechanisms and treatments for chronic visceral pain

Funded by National Health and Medical Research Council
Managed by Flinders University
Managed by The Flinders University of South Australia
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1052340]

Researchers: A/Pr Stuart Brierley (Principal investigator)

Brief description Gastroenteritis activates special types of nerve endings in the gut to cause acute pain. In chronic gut pain, although the damaged tissue has healed, the nerve endings remain active and don’t reset back to normal. This project will identify why this occurs, determining pain mechanisms associated with Irritable Bowel Syndrome, a leading form of chronic pain. It will identify which ion channels and receptors can be targeted allowing the development of novel and effective therapies for pain relief.

Funding Amount $AUD 415,218.31

Funding Scheme Career Development Fellowships

Notes RD Wright Biomedical CDF

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Subjects
G-protein coupled receptors | Medical and Health Sciences | Neurosciences | Sensory Systems | gastrointestinal disease | ion channels | irritable bowel syndrome (IBS) | pain transmission | sensory nerves |
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