De-differentiation of committed cells into haematopoietic stem cells by the instructive role of the transcription factor HOXB4 [ 2014 - 2016 ]

Research Grant

Researchers: A/Pr Nicholas Huntington (Principal investigator) ,  Dr Sebastian Carotta (Principal investigator)

Brief description Blood stem cells are long-lived and can give rise to every cell type of the blood system and due to these properties they are currently used in the clinics. Despite their importance, our knowledge of the mechanisms the control the multiplication of these rare cells is very scarce. This proposal aims to identify key factors that have the potential to convert mature, easy available blood cells into stem cells. This knowledge has to potential to lead to novel system that allow the expansion of stem cells for transplantations in the future.

Funding Amount $AUD 683,040.36

Funding Scheme Project Grants

Notes Standard Project Grant