Understanding the activation of pro-apoptotic Bcl-2 family proteins for the development of modulators of apoptosis [ 2014 - 2016 ]

Research Grant

Researchers: A/Pr Peter Czabotar (Principal investigator) ,  A/Pr Guillaume Lessene

Brief description Programmed cell death is a process by which the body protects against rogue cells, eg cells potentially cancerous or infected by viruses. Dysregulation of the process occurs in cancer and can also lead to degenerative diseases. This work will discover the molecular mechanisms by which key proteins control the life/death switch in cells and will develop compounds capable of regulating their activity, setting the foundation for developing therapeutics aimed at regulating these processes.

Funding Amount $AUD 627,805.45

Funding Scheme Project Grants

Notes Standard Project Grant