STAT3 regulation of cell responses in IPF [ 2014 - 2017 ]

Research Grant

Researchers: A/Pr Cecilia Prele (Principal investigator) ,  A/Pr Steven Mutsaers (Principal investigator) ,  Dr Robert O'Donoghue ,  Prof Darryl Knight ,  Prof Geoffrey Laurent
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Brief description Idiopathic pulmonary fibrosis (IPF) is a fatal disease of unknown cause which is unresponsive to current therapy. This study builds on recent work by this group highlighting the importance of a cell signalling molecule called STAT3 in the development of this disease. In particular, two cell types that utilise STAT3 signalling, epithelial cells and B cells, will be examined to see if blocking their STAT3 responses could be a novel therapeutic approach.

Funding Amount $AUD 680,275.84

Funding Scheme Project Grants

Notes Standard Project Grant