Genetic validation of Stat3 as a tractable pharmacological target in gastrointestinal disease [ 2014 - 2016 ]

Research Grant

Researchers: A/Pr Frederic Hollande (Principal investigator) ,  Prof Matthias Ernst (Principal investigator)

Brief description Cancers of the stomach and the colon are a major health burden. One of the central signaling molecules that drives these cancers is called Stat3. Here we propose to use a novel strain of mice that allows us to experimentally dial down the amount of Stat3 protein and hence to predict how effective a future anti-Stat3 cancer drug will be.

Funding Amount $AUD 586,964.40

Funding Scheme Project Grants

Notes Standard Project Grant