Novel approaches to control mast cell function in allergic inflammation. [ 2017 - 2019 ]

Research Grant

Researchers: Prof Angel Lopez (Principal investigator) ,  A/Pr Michele Grimbaldeston

Brief description Allergic disorders are a major health problem. Driven by mast cells, the underlying inflammation is exacerbated by the ‘?c family’ of cytokines acting on the surface of these cells. We aim to characterise the ‘mast cell-?c axis’ with the view to developing new therapies based on our ?c receptors blocking antibodies. This path of discovery-mechanism-translation seeks to recapitulate our previous success of taking a related antibody to Phase II clinical trials to treat patients with leukaemia.

Funding Amount $AUD 740,492.95

Funding Scheme Project Grants

Notes Standard Project Grant