The role of novel and essential bromodomain proteins in coordinating malaria parasite gene regulation and their potential as anti-malarial targets [ 2017 - 2019 ]

Research Grant

Researchers: Dr Michael Duffy (Principal investigator) ,  Prof Tania De Koning-Ward

Brief description Malaria kills over 400,000 people a year and new therapies are needed. Malaria parasites activate groups of genes by novel mechanisms that could be targeted by drugs. We will characterise a novel group of proteins to identify those that activate genes essential for parasite survival. We will also search for molecules that inhibit the proteins and kill malaria parasites. Thus we will discover how parasites control their genes and identify drug targets and inhibitors for drug development.

Funding Amount $AUD 705,059.53

Funding Scheme Project Grants

Notes Standard Project Grant