grant

Regulation of the androgen signaling pathway in prostate cancer by microRNAs [ 2008 - 2010 ]

Also known as: Understanding how androgens regulate prostate cancer cell growth

Funded by National Health and Medical Research Council
Managed by The University of Western Australia
Managed by University of Western Australia
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/513808]

Researchers: Prof Peter Leedman (Principal investigator)

Brief description Prostate cancer is the most common cancer in men and is dependent upon signaling from male hormones (androgens) for continued growth. We recently identified some novel small RNAs (intracellular messengers), called microRNAs, that are likley to play important roles in maintaining the androgen signaling pathway in prostate cancer. This project will evaluate the functional role of these microRNAs in human prostate cancer, and may provide the foundation for new avenues for therapeutic intervention.

Funding Amount $AUD 540,075.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Androgen receptor signaling pathway | Androgen resistant prostate cancer | Biomedical and Clinical Sciences | Combined miRNA and chemotherapy treatment in prostate cancer | Dentistry | Dicer, TRBP and PACT | Endodontics | Prostate cancer | Receptor tyrosine kinase signaling | Role of microRNAs in human prostate cancer growth | microRNAs and RNA metabolism | microRNAs as potential therapeutics in prostate cancer |
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