grant

The mechanisms of the anabolic actions of androgens in bone. [ 2009 - 2012 ]

Also known as: Male hormone receptors in bone forming cells.

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/566503]

Researchers: A/Pr Rachel Davey (Principal investigator) ,  Prof Howard Morris Prof Jeffrey Zajac

Brief description Androgens (male sex hormones) are one of the few agents that increase bone formation. Androgens act by binding to a specific protein, the androgen receptor (AR). To understand exactly how androgens increase bone formation, we will study mice in which the AR is inactivated only in bone forming cells at specific stages of their development. Understanding the way in which androgens act on bone to increase size and strength will be of great benefit in the design of new treatments for osteoporosis.

Funding Amount $AUD 470,960.40

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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