grant

Wnt signaling in dopaminergic neuronal connectivity [ 2009 - 2011 ]

Also known as: What regulates connectivity in the developing and repairing brain?

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/566740]

Researchers: A/Pr Clare Parish (Principal investigator)

Brief description A major obstacle in repairing the injured or diseased brain is inducing axons (nerve cell processes) to make the appropriate connections. This is especially true following cell replacement therapy (CRT) in Parkinson's disease (PD). We will examine the processes inducing axons in the dopamine pathways to grow. We hypothesize that Wnt signaling plays and important role and that therapeutic introduction of Wnt is required to repair the dopamine pathways following CRT in PD.

Funding Amount $AUD 564,721.19

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

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