grant

Hemokinin - a new inflammatory mediator in the intestine. [ 2009 - 2013 ]

Also known as: Hemokinin - a novel tachykinin in human health and disease

Funded by National Health and Medical Research Council
Managed by The University of New South Wales
Managed by University of New South Wales
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/568861]

Researchers: Prof Elizabeth Burcher (Principal investigator) ,  A/Pr Bridget Southwell ,  A/Pr Lu Liu

Brief description Inflammatory bowel disease and acute diverticular disease are two serious and very costly inflammatory disorders of the bowel. Tachykinins are known to be causally involved in inflammation-induced bowel dysfunction. A new tachykinin peptide, hemokinin, is found in immune cells, but has not been studied at all in the intestine. In this project, we will study the effects of hemokinin on human bowel immune function. The study will provide essential information to formulate new treatments.

Funding Amount $AUD 382,768.59

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Biomedical and Clinical Sciences | Medical Biochemistry - Carbohydrates | Medical Biochemistry and Metabolomics | acute diverticular disease | gastrointestinal disease | hemokinin | human colon | inflammation | proinflammatory mediators | prostaglandins | tachykinin receptors | ulcerative colitis |
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