Effects of Ageing on Hepatic Drug Clearance and Mechanisms of Drug Induced Liver Disease [ 2009 - 2013 ]

Research Grant

Researchers: Prof Sarah Hilmer (Principal investigator) ,  A/Pr Victoria Cogger ,  Dr Brett Jones ,  Dr Rafael De Cabo

Brief description With increasing age, there is increase in disease, for which medications may provide benefit, and an increase in the risk of adverse drug reactions, even after considering the increase in medication use by older people. We will investigate how the liver clears drugs from the blood in old age. This will guide dosing of medications for older people. We will also study how drugs injure the liver in old age and test interventions to prevent this toxicity.

Funding Amount $AUD 581,892.59

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant