Research Grant
[Cite as http://purl.org/au-research/grants/nhmrc/GNT1144829]
Researchers:
Prof Des Richardson
(Principal investigator)
,
Dr Darius Lane
,
Dr James Wilmott
,
Dr Yohan Suryo Rahmanto
,
Dr Zaklina Kovacevic
View all 6 related researchers
Brief description Despite >30 years of research, the precise function of the protein, melanotransferrin (MTf), is unknown. However, we have breakthrough evidence that MTf stimulates WNT signalling as a major driver in cancer progression. We will investigate this hypothesis, which will underpin new cancer therapies. Indeed, we designed a new class of drugs that target the WNT pathway via up-regulating the WNT inhibitor, NDRG1. This drug (DpC) inhibits MTf expression to block tumour cell growth and metastasis.
Funding Amount $613,848.00
Funding Scheme Project Grants
Notes Standard Project Grant
- PURL : http://purl.org/au-research/grants/nhmrc/GNT1144829
- nhmrc : GNT1144829