A molecular balancing act: understanding metal ion homeostasis in A. baumannii during infection [ 2019 - ]

Research Grant

Brief description Bacteria display significant weakness during changes in the abundance of various heavy metals. To exploit this, the host alters the availability of zinc, copper and iron when the bacteria are detected during infection. This study will characterise these host metal fluxes and bacterium's ability to sense and respond to these changes. This will finally elucidate the important role of host-induced metal stress in bacterial clearance and how bacteria overcome this metal stress on a molecular level.

Funding Amount $642,521.00

Funding Scheme Project Grants

Notes New Investigator Grant