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Full Record Details
Persistent URL
http://purl.org/net/epubs/work/55864
Record Status
Checked
Record Id
55864
Title
xtalPiMS: a PiMS-based web application for the management and monitoring of crystallization trials
Contributors
E Daniel (STFC Daresbury Lab.)
,
B Lin (STFC Daresbury Lab.)
,
JM Diprose (Oxford U.)
,
SL Griffiths (York U.)
,
C Morris (STFC Daresbury Lab.)
,
IM Berry (Oxford U.)
,
RJ Owens (Oxford U.)
,
R Blake (STFC Daresbury Lab.)
,
KS Wilson (York U.)
,
DI Stuart (Oxford U.)
Abstract
Abstract A major advance in protein structure determination has been the advent of nanolitre-scale crystallization and (in a high-throughput environment) the development of robotic systems for storing and imaging crystallization trials. Most of these trials are carried out in 96-well (or higher density) plates and managing them is a significant information management challenge. We describe xtalPiMS, a web-based application for the management and monitoring of crystallization trials. xtalPiMS has a user-interface layer based on the user interface standards of the Protein Information Management System (PiMS) and a database layer which links the crystallization trial images to the meta-data associated with a particular crystallization trial. The user interface has been optimized for the efficient monitoring of high-throughput environments, but it could also be adapted for use without robotic imagers. The database can either be an instance of a PiMS database or (as is the case at the Division of Structural Biology in Oxford) a legacy database for which a suitable mapping layer has been developed.
Organisation
CSE
,
STFC
Keywords
Biology
,
LIMS
,
crystallogenesis
,
protein
,
crystallography
,
ISIS 1987
Funding Information
Related Research Object(s):
Licence Information:
Language
English (EN)
Type
Details
URI(s)
Local file(s)
Year
Journal Article
Journal of Structural Biology 175 (2011) 230¿235.
10.1016/j.jsb.2011.05.008
xtalPims.pdf
2011
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