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Persistent URL	http://purl.org/net/epubs/work/64372
Record Status	Checked
Record Id	64372
Title	The influence of high intensity terahertz radiation on mammalian cell adhesion, proliferation and differentiation
Contributors	R Williams (Liverpool U.) (Pr.Au.), A Schofield (Liverpool U.), G Holder (Liverpool U.), J Downes (Liverpool U.), D Edgar (Liverpool U.), P Harrison (Liverpool U.), M Siggel-King (Liverpool U.), M Surman (STFC Daresbury Lab), D Dunning (STFC Daresbury Lab), S Hill (STFC Daresbury Lab), D J Holder (University of Liverpool), F Jackson (STFC Daresbury Lab), J Jones (STFC Daresbury Lab), J McKenzie (STFC Daresbury Lab), Y Saveliev (STFC Daresbury Lab), N Thompson (STFC Daresbury Lab), P Williams (STFC Daresbury Lab), P Weightman (Liverpool U.)
Abstract	Understanding the influence of exposure of biological systems to THz radiation is becoming increasingly important. There is some evidence to suggest that THz radiation can influence important activities within mammalian cells. This study evaluated the influence of the high peak power, low average power THz radiation produced by the ALICE (Daresbury Laboratory, UK) synchrotron source on human epithelial and embryonic stem cells. The cells were maintained under standard tissue culture conditions, during which the THz radiation was delivered directly into the incubator for various exposure times. The influence of the THz radiation on cell morphology, attachment, proliferation and differentiation was evaluated. The study demonstrated that there was no difference in any of these parameters between irradiated and control cell cultures. It is suggested that under these conditions the cells are capable of compensating for any effects caused by exposure to THz radiation with the peak powers levels employed in these studies.
Organisation	ASTeC , ASTeC-AP , ASTeC-MaRS , CI , STFC , ASTeC-Ph
Keywords	4GLS , Biology
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Language	English (EN)

Type	Details	URI(s)	Local file(s)	Year
Journal Article	Phys Med Biol 58, no. 2 (2013): 373-391.	doi:10.1088/0031-9155/58/2/373		2013