#NEXUS

[!This data set was downloaded from TreeBASE, a relational database of phylogenetic knowledge. TreeBASE has been supported by the NSF, Harvard University, Yale University, SDSC and UC Davis. Please do not remove this acknowledgment from the Nexus file.


Generated on April 24, 2024; 6:34 GMT

TreeBASE (cc) 1994-2008

Study reference:
Groussin M. 2011. Adaptation to Environmental Temperature is a Major Determinant
of Molecular Evolutionary Rates in Archaea. Molecular Biology and Evolution, .

TreeBASE Study URI:  http://purl.org/phylo/treebase/phylows/study/TB2:S11359]

BEGIN TAXA;
        TITLE  Taxa1;
        DIMENSIONS NTAX=45;
        TAXLABELS
            Aeropyrum_pernix_K1
            Agrobacterium_tumefaciens
            Anaeromyxobacter_dehalogenans
            Aquifex_aeolicus
            Archaeoglobus_fulgidus_strain_DSM_4304
            Bacillus_subtilis
            'Caldivirga maquilingensis IC-167'
            Candidatus_Korarchaeum
            Cenarchaeum_symbiosum
            Cytophaga_hutchinsonii
            Desulfurococcus_kamchatkensis
            Escherichia_coli
            Haloarcula_marismortui_strain_ATCC_43049
            Halobacterium_salinarium_R1
            Halorubrum_lacusprofundi_ATCC_49239
            'Ignicoccus hospitalis KIN4/I'
            Metallosphaera_sedula_DSM_5348
            Methanobrevibacter_smithii_ATCC_35061
            Methanocaldococcus_jannaschii_DSM_2661
            Methanococcoides_burtonii_DSM_6242
            Methanococcus_maripaludis_S2
            Methanococcus_voltae_A3
            Methanocorpusculum_labreanum_Z
            Methanopyrus_kandleri_Av19
            Methanosaeta_thermophila_strain_PT
            Methanosarcina_barkeri_str._fusaro
            'Methanospirillum hungatei JF-1'
            Methanothermobacter_thermautotrophicus_str._delta_h
            Mycobacterium_tuberculosis
            Nanoarchaeum_equitans
            Nitrosopumilus_maritimus_SCM1
            Picrophilus_torridus_DSM_9790
            Pseudomonas_entomophila
            Pyrobaculum_arsenaticum_DSM
            Pyrococcus_abyssi_GE5
            Staphylothermus_marinus_F1
            Sulfolobus_acidocaldarius_DSM_639
            Thermococcus_kodakarensis_Kod1
            Thermofilum_pendens_strain_Hrk_5
            Thermoplasma_volcanium_GSS1
            Thermoproteus_neutrophilus_V24Sta
            Thermotoga_maritima
            Thermus_thermophilus
            Uncultured_crenarchaeote_74A4
            'Uncultured marine crenarchaeote KM3-34-D9'
            ;
END;

BEGIN TAXA;
        TITLE  Taxa2;
        DIMENSIONS NTAX=45;
        TAXLABELS
            Aeropyrum_pernix_K1
            Agrobacterium_tumefaciens
            Anaeromyxobacter_dehalogenans
            Aquifex_aeolicus
            Archaeoglobus_fulgidus_DSM_4304
            Bacillus_subtilis
            'Caldivirga maquilingensis IC-167'
            Candidatus_Korarchaeum
            Cenarchaeum_symbiosum
            Cytophaga_hutchinsonii
            Desulfurococcus_kamchatkensis
            Escherichia_coli
            Haloarcula_marismortui_ATCC_43049
            Halobacterium_salinarium_R1
            Halorubrum_lacusprofundi_ATCC_49239
            'Ignicoccus hospitalis KIN4/I'
            Metallosphaera_sedula_DSM_5348
            Methanobrevibacter_smithii_ATCC_35061
            Methanocaldococcus_jannaschii_DSM_2661
            Methanococcoides_burtonii_DSM_6242
            Methanococcus_maripaludis_s2
            Methanococcus_voltae_A3
            Methanocorpusculum_labreanum_Z
            Methanopyrus_kandleri_AV19
            Methanosaeta_thermophila_PT
            Methanosarcina_barkeri_str._fusaro
            'Methanospirillum hungatei JF-1'
            Methanothermobacter_thermautotrophicus_str._delta_H
            Mycobacterium_tuberculosis
            Nanoarchaeum_equitans
            Nitrosopumilus_maritimus_SCM1
            Picrophilus_torridus_DSM9790
            Pseudomonas_entomophila
            Pyrobaculum_arsenaticum_DSM
            Pyrococcus_abyssi_GE5
            Staphylothermus_marinus_F1
            Sulfolobus_acidocaldarius_DSM_639
            Thermococcus_kodakarensis_Kod1
            Thermofilum_pendens_HRK_5
            Thermoplasma_volcanium_GSS1
            Thermoproteus_neutrophilus_V24Sta
            Thermotoga_maritima
            Thermus_thermophilus
            Uncultured_crenarchaeote_74A4
            'Uncultured marine crenarchaeote KM3-34-D9'
            ;
END;

BEGIN CHARACTERS;
[! TreeBASE Matrix URI: http://purl.org/phylo/treebase/phylows/matrix/TB2:M8628]

	TITLE Archaea_protein;
	LINK TAXA = Taxa1;
	DIMENSIONS NCHAR=9799;
	FORMAT DATATYPE=Protein SYMBOLS= "A C D E F G H I K L M N P Q R S T V W Y" MISSING=? GAP= -;

MATRIX
[                                                               10        20        30        40        50        60        70        80        90        100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460       470       480       490       500       510       520       530       540       550       560       570       580       590       600       610       620       630       640       650       660       670       680       690       700       710       720       730       740       750       760       770       780       790       800       810       820       830       840       850       860       870       880       890       900       910       920       930       940    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8230       8240       8250       8260       8270       8280       8290       8300       8310       8320       8330       8340       8350       8360       8370       8380       8390       8400       8410       8420       8430       8440       8450       8460       8470       8480       8490       8500       8510       8520       8530       8540       8550       8560       8570       8580       8590       8600       8610       8620       8630       8640       8650       8660       8670       8680       8690       8700       8710       8720       8730       8740       8750       8760       8770       8780       8790       8800       8810       8820       8830       8840       8850       8860       8870       8880       8890       8900       8910       8920       8930       8940       8950       8960       8970       8980       8990       9000       9010       9020       9030       9040       9050       9060       9070       9080       9090       9100       9110       9120       9130       9140       9150       9160       9170       9180       9190       9200       9210       9220       9230       9240       9250       9260       9270       9280       9290       9300       9310       9320       9330       9340       9350       9360       9370       9380       9390       9400       9410       9420       9430       9440       9450       9460       9470       9480       9490       9500       9510       9520       9530       9540       9550       9560       9570       9580       9590       9600       9610       9620       9630       9640       9650       9660       9670       9680       9690       9700       9710       9720       9730       9740       9750       9760       9770       9780       9790         ]
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Aeropyrum_pernix_K1                                     GAE-VYLAPCNPLCT-----QDAWRGMTPEEYKWALCTVAG-----REPDIVIDDGADLHVLLHGGTEETTTGVIRLRALEREGRLLYPVIAVNDALTKFMFDNRYGTGQCTVDGVLRATNILIAGKTVVVAGYGW-VGRGIAARFRGMGAK-VVVTEPVRALEAAMDGFTVT-TMDEADVFITATGNINVIDARHMEKMKDGAILANAGHFNVEINVAALEEM-SVCKRRVRRY-LDE--------YRLPD-GRRLYLIGEGRLVNLVA--AEGHPCEVMDMCFCNQVHRVERIQDEMVARLKLETMGVRIDCLTEEQKLYLQKWDIGDLEEAKERIREIVE-LPMKHPEIFKHLGIEPPKGILLYGPPGTGKTLLAKALANEI-----GAYFICINGPEIMCKYYGECEQRLREIFKEAEENAP------SIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLKERG------RVIVIGATNRPDAIDPALRRPGRFDREIEIRPPDKRARAEILGADLAALAKEAAMAALRGPPGTGKTLLAKA---VATECGANFIAVRGP--EILCKWVDEIDAIAPARGARFDTCGVTDRIVNQMLAEMDG--IQPLCNVVVIGATNRPDILDPALLRPGRFDRGVAHIYCCFNNTHVHITDLTGAETVARVTGGMVVKADREKPCPYAAMIAACRAAQKAMERGIAAIHIKVRAPGGH-GPKTPGPGAQAAIRALARAGFIIGRIEDVTPIPHDTTRRPGGRRGRRGPAGRYGPRYGVCVRKRVRDILARRYQPHECPFCGCTGTVRRVCVGVWCCRKCGNTWAGAAYTPVDKGAAIALAKGAHLMIPGVVGVEGCFTRGDVVGRAVRRVHRLGDYHYIAREWKKPYE-GLHGELMKARLLEWRRQPCILRVEKPTRLDRARALGYKAKQGVIVARVRVRKGGRRKPRPNKGRRPKRMGVYGFAP-AKCLRLIAEERAQRKYPNLVVLNCYYVGEDGRYKWYEVILVDPNHPAIKNDPELNWVTTGKHKGRPFRGLTCAGKKMRGLVVELIHDPGRYVPLARVVRE---DGVEFLMPAAEGMYVGQIIGPAAKPEAGNILPLGKIPEGTEVFNVELRPGDGGKLARQAGCYALPCGKDKEVPNDCRATIGIPAGAGRIEKPIMKAGFAYHKWKVKARKWPRVRGVAMNAVDHPFGGGRHQH-KG--RPCTVAR-TAPPGRKVGHIAARRNIGIIAHVDHGKTTTCDCLLAAAGIICE--RIAGEALVLDYLNVEKQRGITVKCANVCLYHEYEGKP----YVINLIDTPGHVDFCGKVTRCLRVLDGAIVVVDAVEGVMTQTETVIRQALEERVRPILFINKVDRLIKELKLPPEKIQQRFVEIIKEVNNLILDMVIKFVPNPREAQRYRIPKIWKGDINCEIGQAMLNADPDGPLVFFINDVRIEKA-G-LVATGRVFCGTLRCGEEVYLLNA-GKKCRLLQVCIYMGPFREVTKEIPAGNIGAVMGFEDVRAGETECLRYVCEPVVTIAVEPVKIQDLPKMIEALRKLTIEDPNLVVKINEETGEYLLCGMGPLHLEIALT-MLREKFGVEVKACPPIVVYRETVRQQC-RVFEGK------SPNKHNKLYICVEPGVQYLREVKDTIIAGFRLALKEGPLAAEPVRGVKVVLHDAVIHEDPVHRGPGQLYPAVRNAIWAGILDGRPTLLEPLQKLDIRAPMEYLCNITAVLTRKRGRIINVETTGVM-ARIIAAIPVAECFD-LAGELRCATAGRAFWGVEFYGWAPVPDTLANAMAAIKNAEMRGKGEAIIMPCCKLIANVLRILEKEGYIGGFEYID-DGK-FRVKLLGR---INDIG-------VVKPRTPVCYRELAKMPEHLR-KYLA--SRDVGLLILCTPQGVMTHREALKRKIGGIVIAYVYGAGQAVLIGPPNCGKCCILAALTPPLL-PG--SGCCVNNRVLG-LARNADLC-------QYRIYNAIAPRLFRMLDIVRVYTKQPNKEPD-KDPFKY-----ARVGPEHVVED----GDMVNALEVPADLLIRRVARKLKEKYPQVKPPAWAYFAKTGPHKERPPTDR-D-WWYVRAACILRKLYKCPEPIGIETFRTIYGGRQN--RG--SAPEHFRKAGGCVPRKILQQLEEAGLVVKVPG--RGRTICPAGRCLLDTTADGCGMIMGRLACVVAGWR-VNVVNAEKIVLCGDPRMVVECYRTTVLGVKCHFC-HKWRPKRPRTPQRLFKHAVRGMLPK-NKARGCQVK----------------------------------------------------------PCTTELLLKAVCAKA------PCGDPIH-QKIGDLPFEKIVEIAIEKKPDLLAKTLKAAVKTILGCARCIGVTVDGKDPKEVTRQVDEGRAGMTHVFMVDDRPGRPTCGKEIFVPVTIVETPPMFVAAVRL-YGYDPNRG-RYCLGEGNLIAVNDVFEEGQLVDVIAVTKGKGFQGVIKRWGVKELP-RWHKHRKGCRR-IGARCH---GRCTFWETPQAGQTGFHRRTEYNGFLRYGVVRCTFVMLCGCIPGTPKRPIVMRWAIRG-GILPREVAEFFAVALGPGMGPALRVGATVARALCAKYGKPLVPVNHAVAHVEAARFTT-----GLRDP-VALYVAGGNTTVVCFVA-GRYRT-FGETLDIALGNLLDTFAREAGIAPPYVAGGLHAVDRCAE------GG--GFVEGIPYVVKG-----QDVCFCGILTEVAFCCVVEVTERCGGVAANRVLNEKMCLM-AGLHGAVYRPVDVRLCGDNGVMIALTGLAAYLHGRIWLWCTNVRCLENVVEQIRNIANKTGIRMRGPVPLPVKRLEVPVFRLPHGEGCKYWEHWEMKVHKRLIDL-EADERVLRHLMRIKV---PEDVYIEIILFGVLCPHEIRQLAKVTVVRGDLYEADGT-PVCGGLRDPHF-GAIEPGERCPVCGNCREEC---PGHFGKIELARPVLIPHYTD----YVYKILQATCRVCPH-------CRERLEK-TG--SER----PEWMVATVLIVPPLAVRPCITLETGLRCEDDLTHALAEIVRQNEKLRNVIVTNAPETLIEENWMVLQEMVAAYIDNELPGA------RRLTHR-RKRYLKTLAQRLKGKDGRIRGNLCGKRVNYCARTVICPDPYICINEVGVPEEIAKTLTIAMRVTPYNLEEARRYVLNGPDKWP-------GALFVERHLINGDIVLFNRQPCLHRMCIMGHIVRVMPGKTFRLNLLVCPYNADFDGDEMNLHVPRLEEAQAEAREIMLV-EKHILTPRYGGPII--GGRQDYVCGAYLLTGKQLACIFLPDGYRKGTLEPIPGRCLEECLEIKINDVFVMARTGARGCDVNICQMAAMLGQQAVR--------GRRIRRGRVLAHFKENDI-EPEAWGFVRCCFRKGLRPTEVFFHAAAGREGLVDTAVKTCQCGYMQRRLINALQDMAR--VAVVVKVYPDDVCIDPKTLE-PIAFGLKALKLVIAMNEDTEGGTEEVEQLLKNIEGVVCGPKGEVERDFCHARGVLIRLEDNC----VAIAGHIRNMIKGVQGGFRYKLKIMYCHFPINVKVEGDK--FIICNFLGEKGLRIARIM-P-GVKVQV---KG-SD-VIVEGIDVEKVAQTAANIGVDEAGRGCLVGDLVVAGFDCKQLCPAARVELYREIDCRYPVVCAACIVAKVVRDARLQVLRR---MYGGRLMRPVVVVE---NGGVVEMLDPEEGVAAATIGYLEHNQCPRNTYQAAMAKQGVYALN-YRIRLDCHCYLLQY-PQVPVQTRMLDIMG--YNERPA--------GQNMVVAYTGYNIEDALIFNKGCIDMGLARAYFFRVYTGIENEYPGGD-RITLP-KPDEVY--DYRGAAAYAKLEA-DGIVAPETEVRFL--GEGRVIC-MA--TVRRRDTCRLGEKGVVDMVLVKVRVRNLRGDKFACRHGQKGVIGMIFPRYDMPYTENPHAIPCRMGQLLEEIAG-------KAREVMYDGRTGQIIEAPITIGVAYYQRLYHMVADKIHARATGRVHLLTRQPTEGKARQGGLRFGEMERDCLVGHGACMLLRDRMLDNCDAYVMYVCNT--CGYAFKLLLQEITCMMIKPELDAGLFINALNGFPGPYGEVCGCIAREPRGCQ-GFGFDPIF-VP-------EGYC-STFAELGPGVKKRAIARAVIRPGRGRVWINEIYPI-EMARIKMMEPDIRVRVEGGGVMGQADAVRMAIARLRTAFLEHDRTMLVGDPRRTEPEK--YMRYCARRRWQKCYRTKNLVPGQRVYGEREWNAYRCKLLYLGIACGTTACHMCDIIGPRGRIYGVEFAPRVAQPEQAAIVVRNGYML--MAIKA-----RCIDVTTEPCEVYKR-EIKTLVFYNPAMEFN--RDDINPKACMLAALNDIDPYGCPAPFVDAALAL-SGKGTVVAMTATDLAVLEGGKARAAVRRYMLRCVCKTPVCKETGLRVLLGYVARVAAAHDKAVK--PLLAYYADHYYRVYVAVERGARRCDCMLEENLGLYGPPGVGKTCLVEAIALQRICEAE-------RIECEREALRYIAERCEGDLRCAINDLDPCLKRYINLKPVWLPHTGGRHEKRRFGKAEVPIVERLMNKLMGKKHLAYNIVKTAFDIIYFETGENPIQVLVKAIENCAPREDTTKITYGGITYRVCVDVAPQRRVDQALKFIADGARQCA-FNNPKPIEECLAEELILAARGD-PR-SYAIRQKEEIERIALCCRRGRTRTMCWGRIGQHRKCGCKGGYGAAGL---GKHEWT-WTIKYAPT-----WYG--KKGFKLLGEGRVARPLKVITPLACELAIKKIEEAGGGRTLEELL------KMDIEELARLFPARQRRCLLR----GIRTHVRDMVILPEMVGLTIAVYNGKEFIPVKIVPEMIGHYLGEFCPTTRIVQHGEPGLKATRCCLHVACKADNCGAKEVMIICVPQ-V-KTRLRRLPCAGVGDLVVVCVKKGTPQ---MRRQVVYAVVVRQRRPFRRPDGTWVCFEDNAVVIVNPD-GT-PRGCEVRGPIAREAAER-WPRVAKIARLAAEILGVGECRIWICPDPELREEIEGAVTKADVRALIKRGVIKVLPEKGNAGHACKVRHLQRR-KGRRRGMGRRKGVATARL-DPKERWMHRIRKIRRYLRYLRDKQV-IDRKTYRRLYMLAKGGTFRDLACLWQPRTRVGRLVKEGKIKCIDEIFRRNLPILETEIVDYLL-PGLGRITRFRAVVVVGNKDGYVGLGKGKARQFRFAIEKAIRNAKLNIIPVRRGCGCWECTCGEAHCVPFTVRGKCGCVEVILKPAPKGTGLVAGDVAKVVLRLAGICDVWTFTKG-----ETRTCYNFARATYLALEWLAQNFYEAGYCRVKVVQT-SLGTNITIWAERPALIIGRRGATIRRLQEVFQTVFG-LPNPRIRVEQP---ENPMLDARVQAFRIARCIERGIH-FRRVAFAAINRIMCN-GALGVEITICGKLTC-ERARFEKFKAGKVYKCGHKVDELVDRACAYARLPKGVIGVDVIIVKP--G-KPGDLRRLLTCKARERLANLRLVRPEIAEAAENAVIQLVQTGRITPPVDDDTLVQILAAGRGYPKVTGVLPVALERMTRIIGTVMHCCKEYFEGEIYQKPPLRCCVRALRTRRVFRIEL--LGTYMRKLCWDIGLVLGVGAHMRELRRIRTGPFCEDCGLMVRLPGEYCVCHIPKVLVRDCAVECLTHGAQLAAPGVALMTLKGELIPAVRKPERKPTLYRRL-AWTGVILVLYFIMCNIPLYGG--TLMELGIGPIVTACLIIQVLVGA--KIIKLDLAD-PEGRRKFTCAQKQLFL-GALLVIYFDEVMQKG-----IGCAICLFILAGVTLAAIILLVYLQAMRVEIPPLQFIYVTNIPILFGYM--WVEIAGLNP-REQAERLIKGGLAIPGMRCDPRVLERVLRRYIYPLTFLCCLIVAALVIVADIF---GAYG-------TGTGLLLAVGIINQYYAMITRERALETYPLKKRGAVLRGD---FVLCCGRRCYIDMRRLLGDEP--L--GYVRPERKGTLCQ--VEG-DPP---KGRVVVVDDVATTGTCIAKCIEVLRCNGGLFAARKLRRKRLKFRWCQREFRIRML-DLKRKYDPLEGA------PMARGIVLEKVGVEARQPNCALRKVRVQLVKNKKVVTAFVPRDGGILYVDEHDEVIIEGIGGPRG-RCMGDIPGVRYRVVM--VNGVCLKALWEGK----KQKPRKLVPCELYR-----KAGVIYGTQIC--TRYMRQ--FVHRILP-EGYYQLDYLKIDERLAMAAKFLCTF--EPEKIAVVCVRIYGQKPVRMMCERVGCKAITGRIIPGTFTNPNLEHYVE--------PDVVVVTDPRMDRQAVVEACKVGIPVVALVDTDNCIENIDLVIPANNRGRRCLALIYWILTR-EI---LRRRKQAIVVRRDLGMGRGKAAAQAAHAWRLQGQAKVVLRVECLAELQEVYCKAVEEGLPACFVRDAGKTQLEPGTPTAAAVGPAPCRLVDRITGGLKLKYVIVTGGVLCCVGKGLTTACLALLLCCRGYCVEAIKIDPYINVDAGTMNPYMHGEVFVTED--------G-----GETDLDIGHYERFLGKNLCRKHNITTGQIYFCVICKERCGDYLGQTVQVIPHITDEIKCRIDVVIVEIGGTVGDIEGLPFLEAARQMRLEEGFDNTFFIHVALCPYLPTTGEQKTKPVQHCIQELRRIGIQPDAVVVRCHQPLEQEGLRKIALYATLPMENVINCYDIENIYRLPLLLEKQGLRDCYICIVEALKHDGAIVLPGFGVRGVEGKIEAIRRFREGKKPMLGICFGMQLCVVEYARNVLGLKEAHTTEVNPETPHPVQRGI----DKLGGTMRLGARPVRIVEGTILWCLY-GRELACERHRHRYEVNPT-YVDRLVEAG-----LVVC----AWC-QEG-YVEAVELRPRD--HPFFLATQFHPEFKCRPLNPAPVFKRFKQCVEIIVALKDIDLKC-PQARIRETVFLPNRPP-KEAKVCVVAHGDMELQAKEAGVE-VLNRQDLQNLCQNKREVKKLARRCYWVLVRADLMGLAGRIL-GPALGPRGKAPVWVRIRNQPQVMARIGTEDMCPRELAENALAVLQVIENRLGRG----KICRIYVKKTMGMGDPRKP-RKKWEG--PKHPWIKERLERERELMGRYGLR---NKKELWKAETLARRF-RH--RARCLLYRMGLI--DNPNVDIDEVLGINAEKVLERRLQTIVYKKGLAKTIYQARQLVVHGHIAIAGRRVTCPGYLVCREEEKLI------------MLEEENTLTFIVRREATKNDVKRAVEQLFGVKVEKVRTKKAYVKLAPEY--KALDVATKLGVYDERGGEKDCVVL-PQIFRFPVRKDLIRRAFLCEFTARLQPKGRDPMAGKRTCA------VCLGV--GRGVARVP-R--IKGCL-----R-AALVNMARGGRAAHPPRVEKVLKEYINKKEKRLATICAICATCREDLVRQRGHRFCA-ETL--PIVLDCCVLAKICTAREARCLLECVGVYEDVLRAKEGK-RYNAGKGKMRGRRYKVPKCVLFVGMPGVDVVTPTLLCVLHLAPGGHPGRLTIYTTEAAWMEVRGKRFEILVRPELAFRYK--EKG-D-VDLEDVLWTDTIYRDVRKGLKACPEEVKKAFGTCDPRRVAEKILKEGEIQLTEEQRRRLLEAKRRQIICYIARNAIDPT-TGRPIPEARIEAALEEVRFPINLWRDAECQAVEAVRLIARVMPIRLARALLEVKIPPPHCGRAYQALMRMG--EVKKADWLPDGCLKAEL-EIPAGAQVEVTCRIQALARGVRKIRCGVVIDHIPPGRA--------FTMLKALGLLP-PRGYRWRIAVVINAECCKLG-R-KDILKIEGYKPRQRDLEVLGIIAPGATFNVIEDYKVVEKVKLKLPEECQGV--LRCPNPTCITRKER-EKAVCKMVLV-SQD-PPAYRCVYCTCLVTRRLIGELRRAARRNCAPVWLRVAELLERPRRRRA--EVNLCKINRHARDG-----EMVIVPGKVLGAGALEKK-VTVAALCFCLQALVKIRLCGCRA--ITLEEAVR--ENPRGCRTRIPVRCFTCGRPLGHLWPRFRELV--ACGK---TP-----GEALDELGVDRYCCRRTLFTCLKKGCYIVI------DGEPCRIVEMCRAKTGKHGCAKAHVVAICVFCGQKKCLVAPVDTRVQIPVIEKRLGQVQIMDLETYDTGVTVEYWLI-MGKPKIKYLIRARLEVDGRVDV-----IGAFGQTECLLGCDF----SLEELQNKDKLGRIA---AMLETIDK--------IGPYPAKITIEEIRDLRLERLEKIKQRAVEKADTIIVVEGRCD------VNTLLR--YGYTNVIAGAREKVPETIKRLAEQKKV--ILFVDGD--------RGGEL------ILKNVLPQ-MKVD---YVARAPEGR-EVECLTGRE----IAQALDIACEK--GVGIIIGNRIGNKI-THKPMRRPRIVKVTVNICIGQC---GERLQRAAEVLEELT-GQKPVFRKAKRTIRAFGVRKGENIAVMVTLRGEKALNFL-KRALD--AV---GHR-IKTCCIDEHGNVCFGIEEHILIPGVKYDPRVGILGRIVITRPPEVTAVKP-VAKLRLEDYILIAGAPGMGKTTFAQALATFYAEQ-GK-VVKTIECPRDMRLPP---NVTQYCKNYA------DLGELHDIL--------LLCRPDYTVYDELRCDEDFQLYVDLRLAGI-GMIGVVHATTPIDAVQRFLRRVELGMIPCI---IDTVIFIDCGEVCKVYELCITVKLPTGLRE--AELCR-------PV-VEVRDF--ITGELEY-EWRDKKKPCGG-KRRYYYKVKRKYAAGRPPTYTTLCAAEEE-ERKPVRARGGCYKIKAKKVAFAVVCNPKTGEARKARILRIVETPAHREYARRGIIVKGAVIDTTLGRAVVTCRPGQEGVVNAVLAGRIAAEAREYAAGLVEAGACCRRVCELVEEKIR-SLGAVPA------FP--CNICLDCVAAHYTPGLRDDCCIGGGCVVKLDVGAAVEGYIADTAVTLVEACVEGLRAAMKVLKPGARFYDIGRAVEQAVRRRGFKVVKNLCGHTIDRYTIHAGLC-IPNGMTFAIEPFAT--NGRGMVREGCTVNILIEAGGGLVCQAEHTFYALRGGIVVVTCK-PKKCC-YECIAVCPIYEDACIG--CALCVKACPFDAIYIVNLPMELEEE-AVHRYGVNGFKLFRLPI-PREGQVVGLLGRNGTGKTTALRILAGELKPNKIQ-----YVEL---VPRRL--KGR-VRDLLKRADER---G-VALELAEQVGLDKVFDRDVRQLCGGELQKMLIVAVLCRDANVYIFDEPCCYLDIRERMRMARLIAGAAR----PGAYVMVVEHDLAVLDYVCDLVHILYGEP--GAYGIVCKPYCTREGINVFLQG----YLPAENIRLRFTLTCGEGA-LYGGEVIGVAGPNGIGKTTFVRTLAG--ALKPVE------GY-------KPQYI-SPECL-PDATVEQVLLCGGELQKVAVAAALAREADVYLLDEPCAYLDVEERVGVARAIRRIVETREAAALVVEH--------D
Agrobacterium_tumefaciens                               GAE-IRWACCNIFCT-----QDAVKGECLTEYWEYTDKIFQ-WTDGGLCNMILDDGGDATMYILGVTEETTTGVHRLYDLAKKGLLPFPAINVNDCVTKCKFDNKYGCKECLVDGIRRATDVMMAGKVAVVCGYGD-VGKGCAACLQGAGAR-VKVTEPICALQAAMDGFEVV-RLEDVDIFITTTGNKDVIRIEHMREMKDMAIVGNIGHFDNEIQVACLRNL---KWTNIKPQ-VDM--------IEFPK-GNRIILLCEGRLLNLGN--ATGHPCFVMCACFTNQVYVLPKHLDEKVARLHLEKLGVRLTELCDLQADYIGICDFTGQAEARANLKVFIE-AAKNR--------GEALDHVLFVGPPGLGKTTLAQIMAKEL-----GVNFKCTCGPVIAKA--GDLAALLTN-LEERD-----------VLFIDEIHRLNPAVEEILYPAMEDFQLDLI-IGEGPAARCVKIDLCKFTLVAATTRLGLLTTPLR--------------DRFGIPVRLGLNMTD-----------GTPRIAGRLLRRV---------RDFAEVARA--EAVTREIDN-------MGLDQLDMRYLTMIAVNFGGGPVG--IETIAAGLCEPRDAIEDIIEPYMIQQGFIQRGVAHVNCTFNNTMITITDAQG-NAIAWCCAGAKGFKGCRKCTPFAAQIAAEDCAKKAQEHGMKCLEVEVCG---------PGCGRECALRALQAAGFMITCIRDVTPIPHNGCRPR---KKRR????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????VERLEYDPNRTAFIALVTYT---DGEQAYILAPQRLAAGDKVDKAVDVKPGNTMPLQYIPVGCIIHNVEMKPGKGGQIARCAGTYVLNCGEQRLVHGCCLACIGAVCNCDHGNINDGKAGRC--RWRGKR---PHVRGVVMNPVDHPHGGGEGRT-SGGRHP------VTPWGKPTKGKRTRRNFGIMAHIDAGKTTTTERILYYTGKCHKIGEVHDGAATMDWMEQEQERGITITCAATTTFWKGRDGKM---RRFNIIDTPGHVDFTIEVERCLRVLDGAIALLDANAGVEPQTETVWRQAEKYNVPRMIFCNKMDKTGADFYRCVEMIKTRLGATAVVMQLPILDAVVDYLPCPLD-----IPAIKGIDFKTE-AEIERHADDCEPLCMLAFKIMNDPFVG-SLTFARIYCGKLEKGTCVINTVK-DKRERVGRMLQMHCNCREDIEEAFAGDIVALAGLKETTTGDTERMEF-PEPVIQIAIEPKTKGDQEKMGLALNRLAAEDPCFRVKTDEECGQTIIAGMGELHLDILVD-RMRREFKVEATVGAPQVAYRETITRQHEEDYTHK--KQCGGTGQFARVKIIFEPGGAVPKEYIPGVQKGIECVLCCGPLAGFPMLGVKATLIDGAYHDV--DCCVLAFEIACRACFREAAKKAGAQLLEPMMKVEVVTPEDYVGDVIGDLNCRRGQIQGQECRGIT-IVICAHVPLANMFK-YVDNLRCMCQGRAQYCMTFDHYCPVPDPLGDMLTRIRNGAARRKCCVCT-PACCLRARVLDVLQCEGYIRGYCKVDFEAE-FTIELKYY----EGAC-------VIREIGRVCKPGRRV---YVCVKCIPQVANGLGITILCTPKGVMADHQAREQNVGGEVLCCVFRGEITALIGPNGAGKTTVFNCIT---------RLPDFEITKKAKVARTFQLG-------LPAYKRALPYGAQRRLEIARAMCTGPELLCL-DEPMCV-----VMQCPDHVKND----PK???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DAEGLVVGRLATIVAGDN-VIVINAEKVAFTGKKYCDKKYYW-HTGHPGGIKERTARQIIEGRFPERVVEKAIERMIP--RGPLGGCANPCPPIGPALGQRGINIMEFCKAFNAATQEMEK-GMPIP-VVITY--YQDKCFTFAMKQPPMTYWLKKEAKITC------GCKTPGKGAKVGCITKAQVKTIAEAKMKDLNAADIEGAMAMVEGCARAMGLEVVG-------------KVGMTRVYNDAGE----------HIPVTVLRLDNVQVVAQRT-EDKNGYTAVQLGAGQGATLTANH-FQCGQLVDVTGTTIGKGFAGAMKRHNFGGGR-ACHGNCVCHRA-HGCTGNNQDPGRVWKGKRMAGHMGQTRVTTQN------DEDRGLILVKGAVPGCKGCWIIVRDAVKG-GVVPEIAARAHAATCGPGLIGGLLVGLMTGKAIAKAAGKPLYAINHLEGHALTARLTD-----GLCFPYLMLLVCGGHTQLVLVRGVGEYER-WGTTIDDALGEAFDKTAKLLGLPYP----GGPAVENAAA------KGDPDRF-PLPRPMVG--EARLDFCFCGLKTKAVCRTLKDRIGRGGGVAANQEIRQTLQAL-CDTHGFRFVAPPHRLCTDNAAMIAWAGLERMAEGRIRLKAFDHRILDACTREIVCTAKRTGACVRGPVPLPTRIEKFTVNRCPHV-DKKCREQFEMRTHKRLLDIVDPTPQTVDALMKLDL---AAGVDVEIIRICIACPEKILCWCYGEIKKPETINYRTFKPERDGLFCARIFGPIKDGIICEKCGVEVTLCRVRRERMGHIELAAPVAHIWFLKCLPCRICTLLDMTLKDVDE-------FRAELAETTCDLKQR----PEWMIMKVVPVIPPDLRPLVPLDGGRFATCDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQECVDALFDNGRRGR------VITGA--NKRPLKCLCDMLKGKQGRFRQNLLGKRVDYCGRCVIVTGPELKLHQCGLPKKMALELFKPFI--------YARLDAKG---------------YILDEVIREHPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCAFNADFDGDQMAVHVPLCLEAQLEARVLMMC-TNNILHPANGHPII--VPCQDMVLGLYYLCGRMLIGELLPDGYNDGLIT-------QGEKYNKVNCIYMMCHCGARGCPNQMRQLGGMRGLMAKPC-------GEIIET-------------------PIICNFKEGLTVNEYFNCTHGARKGLADTALKTANCGYLTRRLVDVAQD??????????????????????????????????????????????????????????????AKGPKGELFFVAND--DIQLKLEDNG----VMCRTMIENIFKGVKDGYERKLEINGVGY--RAALQGKN----LQLALGFCHDVVYEP--PVGITIAV---PKPTE-IIVCGINKQQVGQVAAEIGTDEAGRGPLAGPVVAAAVDCKKLTRQKRECLFVQIDCRCLCIAAACIIAKVTRDRMMERAGVVHTCYGGAFTEEFVVCRH--SGALIPFLENDDARDCGAAIAARRGGVVDQVDATRIVIRGKCGVDIYRLQKFQRCNQNTCVNQRPVCVGDAICKGDIIADGPCTDLGDLALGRNALVAWNGYNYEDCILMCERIVCDDVFTCIHIEEFEVMARDTKLGEITRDIP----------NVCEEALKNLDE-AGIVYIGAEVKLL----RAIFG-EK--ACDVRDTCPPGTFGTIVEVMVKVFVAVKRGDKMAGRHGNKGVVCRIVPVEDMPFLENPLGVPCRMGQILETHLA-------WGQCVLYDGRTGEPFDRKVTVGYMYMIKLNHLVDDKIHARCIGPYCLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKCDDV---------AGECFNVLVKEMRCLGLCVELDCGLVIDALDGAPGVYGEVEGTVVWPPRGTC-GFGYDPIF-KP-------DGYD-TTFGEMCADEKKNAVARVWVKAGCGKIIINTTYFARPVLQMILQQPDIIATVAGGGLCGQAGAVRHGVCKLRPVLKKGG--FLTRDCRVVERKK--YGKAKARRCFQFCKR?????????????????????????????????????????????????????????????????????????????????????????????????????????AIATTEVDEK--RDDVD-----WIAKCKVQPHDLAIE---------IEAGQAFGTGHHGTTAGCLEMIEDVLRARKVRNA--LDLGTGCGVLAIAVRKMRPIPVLATDID--PIAVKVAKENVRLNGIV------SGMALETAPGLTGVRGVGKTTTARILAFTAIAGKE-------GFEAEPQALCMIARAAEGCARDGLCLLHCAEKREINPDPKF----------------GDLVVTKFMNAIMGKKCVAECIVYGAFDVVQGKTKQEPLGVFHCALDNVAPHVEVRCRRVGGATYQVPVDVRPERRQALAIRWLITAAR----KRNETTMVDRLCGELMDAANNR----GCAVKKREDTHKMADANR?????????????????????????????????????????????????????????????????????????????????????????????GPFVD----------------------------------GIKIWCRRCTILPQFVGLTFGVYNGCKHVPVCVNEDMVGHKFGEFCPTRTYYGHGADKKAKRK--------ADNCGARRVMCIKVLG----GCKRKY--ACVGDIIVVCIKEAIPRGRVKKGDVMKAVVVRTAKDIRRADGCVIRFDNNAAVLIDNK-KE-PIGTRIFGPVPRELRAKNHMKIICLA???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????----------MAQEKRGCRDD--RQNREERDCEFV--------GRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATECAKRDLIFVPLRDG---------RTLHHDVNGRHGAGKVLLRCAKAGTGIIAGGPMRAVFETLGVHDVVAKCTG------SCNPYNMVRATFDALAYLIKELKQAGIAKVVIERP-HKKCRVTIHCARPGLIIGKKGADIEKLRKKLCEMTN--SETHLNIVEV---RKPEIDATLVAQCIAQQLERRVA-FRRAMKRAVQCAMRL-GAEGIKITCGGRLGGAEIARTEWYREGRVPLHTLRAD--IDYGTAEAETAFGICGIKVWIFKG--EILEHD?????????????????????????????????????????????????????HAGTLDPLACGMLPIALGDATKTVPYVMDGRKIYYTGVIMQTPPQFCAIIPAREVEIHRLTL--LGTYVRALARDMGRDLGCFGHICELRRTMVAPFGEDMM--VPLDTAEALCCLPRLIINDDQAHRLKMGNPILLRGEAYATAQGKLV-----------------------------------------LNAAGAEPYLGRC----------------------------------------------------------------------------------------VPPCRLI--------------------------------------PEFAR----------------TFVNRFGRQRIEDLQNAF--------------ADTQI------------------------LWEIKAVHFNCECPYTFACGMKCYIDMRKLICFPP--M--IYCRKKPKGRNAQ--IEG-HMP--DGARVLVIEDLTTAGGCMFTFIDAIRAAG-MPTVNQLIRKPRQAQ------------VKRNKVPALQEN------PQKRGVCTRVYTTTPKKPNCALRKAKIRL-TNGFEVIGYIPGEG--HNLQEHCVVMIRG-------GRVKDLPGVRYHIIRGVLDTQGVKNRKQRRCKYGAKRPK-DFCMRQLL-----EAGVHFGHQTHRWNPKMKP--YIFGDR--NNIHIIDLAQTVPMLCRALQVVCDTVARGGRVLFVGTKRQACEIIADCAKRCAQYYVNCRWLGGMMTNEKLEKALGGIRDMGGVPDLMFIIDTNKEKIAIEEAKRLGIPVVAIIDCNCDPDHIDYPIPGNDDACRAICLYCDLIARAAIDGIARQQ???????????????????????????????????????????????????????????????????????????????????????????????RYVFITGGVVCCLGKGIAAAALGALLQCRGYRVRLRKLDPYLNVDPGTMCPTQHGEVFVTDD--------G-----AETDLDLGHYERFTGRCATKTDNITTGRIYKNIIDKERRGDYLGATVQVIPHVTNEIKDFVDFVICEIGGTVGDIEAMPFMEAIRQLGNDLPRGTAIYVHLTLMPYIPAAGELKTKPTQHCVKELQALGIHPDILLVRADREIPEAERRKLCLFCNVRPCAVIQALDVANIYDVPIAYHNEGLKDAYKCLIEALHHNGILVPGGFGERGCEGKIMAAQFARERNVPYFGICFGMQMAVVEAARHLAGIENACCTEFGP-TAEPVKRCT---KGDLGGTMRLGAYKAALKKDTKIAEIY-GTTDICERHRHRYEVNVD-YKDRLEECG-----LVFC----GMC-PDGVLPETVEY--PD--HPWFIGVQYHPELKCRPLDPHPLFAKFDETVEVCMNL-GVDPRH-ADQMVRGVVNLPNGTG-RDVRVAVFARGVKADEATAAGADVVGAEELVEIVQGGKI-------DFDRCIATPDMMPLVGR-L-GKVLGPRGMMPVEFRVEKAGIVHAGIGKACFDAKALEENIKAFADAVIKAKPTGAKGNYVKRVAICCTMGMCKRECA-KYKIDRRMGENIWGR-------------------PKCPVNRREYGPGQHGQR--RKGKMLREKQFRATFDEANRRKGDTCENLICLLECRLDAIVYRAKFVPTVFACRQFINHGHVTVNGVRVNIGCYRCKAGDVIEVIVCPCITEKC-TLVCEQNQVVFNVAKTACKPEIKAAVEALFGVKVTAVNTKKAVVTLAEGQ--SI-DVCTGL-VKTLEGKDAGKVCLCDEIFGLDPRQDILARMVRWQLAKKQQ--------GTHKTK------NRCEV--SRTGAKMY-K--QKGTGRAR--HHCARAPQFRGGGKAHGPVV-RCHAHDLPKKVRALALRHALCAKLKAE-----------------ELIIVDQLVACEAKTKALLGCFACLGLTN----------ALVIGGAELDGN-----------NIPNVDVLPVQGINVYDILRR---GKL-VLCKAA?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????LDEIRDRVNICDVIDR-----KGRHCFGCGVCGDHFRFLTELEGLCFPEAVQQIARARAYLRDRGL--------TGRTIETFRLGYAPDCRNALKEHLACKGQAAGGTVIAVEGYMD------VIALYQ--AGVENAVAGTA--LTDCQLDLLWKMCPQPVLCFDGDGAGIRAANRAADL------ALPHIKPD-RCVC----FALLPDGK-DPDDLVRLEGRAPFDRVLAEATDDERGTLLVRAIAEV-QLEIGRMMMIPKLDKIVINMGVGEATADCKKPTIAAGDLAAIA-GQKPVITKARNCIAGFKVREHMPIGAKVTLRGERMYEFL-DRLINIALPRVRDFRGLNPKCFDGRGNFAMGIKEHIVFPEINYDKVDQMWGRIQIVIPPCMTIRKPCCVDFCLDDLIIICGATGCAKTTLCKALIKHIPEN-ER-VICIEDTPELVICQPNHVRL-FYCKGRQ-GLCRAGPKELLECC--------LRMRPDRILLQELRDGTAFYYIRNVNCGHP-GCITTVHANCAELAFEQLV---------------------------------LLVKECEGV----AGLDR----------ADIVAL--LKACIDI--?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????ACQLTARCLDELAAIVKPGVTTDAIDRFVFEFGA-DHGALPATLNYRGYTKCVCTCINHVVCHGIP---DEKPLRDGDIVNIDVTYVLDGWHGDCCRMLMEVTYECLMRGIAAVKPGTRTGAIGAAIQAYAEAERCCVVRDFCGHGVGR-LFHDTPN-ILHGMIFTIEPMIN--LGKPHVKVLCDG--AVTRDRCLCAQYEHAVGVTATGCEIFTMVTPCATN-TKNDPGAP-DVRLAFG-----------------------------------STVALADICVEIPAGRMIGLIGPDGVGKCCLLCLICGARAIQCVFE----NIDF---FGRLFGQDGR----------ER---KARIAELLKCTGLERFADRPAMKLCGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLCRRQFWELIDCIRA-----GRPGMCVIVATAYMEEAAGFDWLVAGCP-----GELLERTCTANLDAAFIA-----LLPEEK-RKDFTAVDNVCFKIPRGEIFGFLGCNGCGKCTTMKMLTG--LLAACE------GY-------MCQAF-SLY---SELTVRQNLLPLGIRQRLCLAVAMIHCPDILILDEPTCGVDPVARDGFWQILADLCRNDNVTIFICTHFMNEAERCD
Anaeromyxobacter_dehalogenans                           GAD-VRWACCNIFCT-----QDAWKGETLEEYWDCTERALD-FGGGKGPTQIVDDGGDATLLIHGVTEETTTGVHRLYEMQKAGTLLFPAINVNDCVTKCKFDNLYGCRHCLVDGLNRAADVMLAGKLCVVCGYGD-VGKGCAQALRGQGAR-VVVTEPINALQACMEGYQVV-RLEDVDVFVTATGNLDVVTVEHMKAMKDCAIVGNIGHFDNEIDMAGLRK--AATRVNIKPQ-YDA--------FVFPD-GHRVLVLAEGRLLNLGC--ATGHPCFVMCNCFTNQVYVLPKHLDEKVAALHLEQIGARLTKLCKKQAAYIGVPDYVGQVKIVDNVKVYAA-AARQR--------GECLDHVLLCGPPGLGKTCLAHILAREL-----GVTLHVTCGPALVKK--GDLAGLLTALAPR------------DILFIDEIHRLCPAVEEALYPAMEDYRFDVV-LGAGLGAQTMEMKLERFTLVGATTRTGLLACPLR--------------DRFPIQERLGLPVD---EDGAEELARGTPRIAIRLLQRA---------RDFAQVEGD--GRLTREV-EVDA----RGLDAMDRRILAAVIDTFGGGPVG--IDAVAAAVGEECGTLEDVYEPFLVREGYLARGIVHIACTFNNTQITITDVTG-NVIAWCCAGARGFKGCRKCTPFAAQVAAGDAAAKAMEHGLKTVCVVVKG---------PGAGRECALRALCAAGLKITLIRDVTPIPHNGCRPP---KRRR????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????VAAIEYDPNRTARIALLHYL---DGEKRYILAPVGVAVGDTLGADVDIRPGNALPVRTIPLGTVIHNVETAPGCGAKMIRTAGCFGLPCGEVRKVLQDCKATIGQLGNVECCCVRVGKAGKC--RWLGIR---PTVRGLAMNPVDHPHGGGEGKCGQG--NPHP----VCPWGQKTKGLKTRRNFGIMAHIDAGKTTTTERILFYTGVTHKIGEVHEGTTVMDWMEQERERGITITCAATTAFW----RD----HRLNIIDTPGHVDFTIEVERCLRVLDGACAVFDAVQGVQPQCETVWRQADKYEVPRICFINKMDRVGADYFHAVDTIREKLGARPLPLHVPILDAVVDFLPCPVD-----IPAMKGVDAKGN--DVVRKTCDAEPFCALAFKIMNDPFVG-NLTFFRVYCGRLEAGCYVYNCTK-DKKERIGRLLQMHANKREEIKEVYAGDIAAAVGLRACTTGDTERMEF-PEPVIHIAIEPKTKGDQDKMGVALQRLQMEDPCFRVHTDEETGQTIIGGMGELHLEILVD-RMFREFKVEANVGKPQVAYRETITRTV--EAEGRYIRQTGGRGQYGHCWLRLHPGGVIPKEFICPIQKGIEEAMTCGVLAGYPMVDLKVELFDGCYHDV--DCCEMAFKIAGCMGFKEGAAKACPVLLEPIMAVEVTTPDDYMGDVIGDLNCRRGKIHAMNPRAGV-QVIEAHVPLAEMFG-YATDLRCKTQGRATYCMQFAHYAQVPDPIGDMLTRIRNACCARHEKCLV-PACRLKVRIAEVLREEGFIKDFVLHE-DGA-ITIVLKYC---ADREP-------AICDIKRVCKPGLRR---YVATDCIPRVLNGMGIAILCTCKGVMVDREARKQKVGGELICTVWGAGQWVMIGPANCGKCCLLAALTPAV------GGAQVPAWLPQ-LVHGAD----------------LRPVLFRCLHRIRVHTKEPGHAADGGKPLKF-----ARLDRGHVLGD----GD???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DATDLTVGRAATRIAGDF-VVVVNAGKVRFTGNKETDKVFFT-HTMHPGGAKQ-TPMNKLRERHPEQIIENAVRRMLP--RNNLGGKANPAPPVGPALGQHGVNIMEFCKQFNAATQAQAKEALIIP-VIITV--YQDRCFTFVLKTPPAAILLKKAAGLHTEKKKGCGAHKPGK-EKVGQVTRKQVEQIAKTKMQDMTAGTLEAAMRTVEGTALCMGIEIVG-------------KVGMTQIFTPEGD----------CVPVTVLEAGPCTVVRRKT-AEKDGYDAVVIGFGVGDVLTVDKVFKANQRIDVAGVTKGRGFTGVMKRWNMKGAARDCCTAHEHHRH-VGAIGQRKTPGKVWKGKHLPGHYGVDNITIQN------EPEQNVLLVCGAVPGHADGLLFVNTAAKG-GVVPELACRNHAVTCGPGLVGALLVGVQAAKALALAWGKPLVGVNHLEGHLVAAFLAEV----PPAFPYLGLVVCGGHTCLYAAHGFGDYRL-LGQTRDDAAGEAFDKGAKLLGLPYP----GGVAIDRLAK------EG-DPAAIRFPKAIVK--GADLDFCFCGLKTEAIVRALVEKAFRAGGVAANCRLRAAATARAAEYEGMCVFIPPVRLCTDNAAMIAVAGTHALLRGRIRLKAYDYKLLDQCAGEIVETAKRTGAKVAGPIPLPTRINKFTVLRCPHV-DKKCREQFEIRTHKRLLDILEPTPQTLDALMKLDL---SAGVDVEIIRICLACPDKIRQWCHGEVKKPETINYRTFKPERDGLFCAKIFGPVKDGVVCEKCGVEVIQCKVRRERLGHITLATPVAHIWFLKCLPCRIGNLLDITLKDLDE-------FDAKRKKIAK--RLK----PEWMMLEVIPVIPPDLRPLVPLDGGRFATCDLNDLYRRVINRNNRLKRLQELNAPDIIIRNEKRMLQEAVDALFDNGRRGK------TITGP--NKRPLKCLCDMLKGKQGRFRQNLLGKRVDYCGRCVIVVGPELKLHQCGLPKIMALELFKPFI--------YNKLEEKG---------------YILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAFNADFDGDQMAVHVPLCIEAQMEARVLMMC-TNNILCPAHGKPII--VPCQDIVLGIYYMTGRVLLYDIVPDGYTEGLIT-------IGERYNKVNPIYIMADCGARGCAQQIRQLAGMRGLMAKPC-------GEIIET-------------------PITANFREGLNVLQYFICTHGARKGLADTALKTANCGYLTRRLVDVAQD??????????????????????????????????????????????????????????????VEGPKGKMHFPTNP--LVCVQVDKGE----VLTRTLVKNALEGVVKGYEKGLEINGVGF--KAEVKGKE----IHFTLGFCHPVVFKL--PEGVTAEV---DAKQTKLTIRCVDKHLLGLTAAKVGVDEAGMAPLAGPVVAGACDCKQLDRAERERLAEDIDALCLTIAAACILAKTARDALMAELDLAHPGYGGNFTEAKVWCRK--EGCLVPFLENDDARDCGVTTVAKRDGVVQCVDACRIVVKANEVDI-YNLIKYQRCNQNTCINQKPVKPGERVRKGDVIADGPATEMGELALGQNVVVAWQGYNFEDCILLCERLIKEDVFTCVHIEEFECVARDTKLGEITRDIP----------NVGEEALKDLDE-SGIIRIGAEVKLL----RAIFG-EK--AGDVRDCCPPGVCGTVINAMVKVYVAIKRGDKMAGRHGNKGVVCRVLPEEDLPYLENPLGVPCRMGQILETHLG-------WLQCILFDGRTGEPFDQDVTVGVMYMLKLHHLVDEKIHARCIGPYCLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYCLQEFLTVKCDDV---------VGECFNVLIKELQCLALDVELDCGLCVDALGGAPGVHGTCPGRIGHARRGDG-GFGYDPLF-VPAAELAAGEGARVRTMAELCCDEKKEAVARVRLVPGTGNITINDEYFGRETCKMILVEPDVFVNAAGGGLCGQAGAIRHGICRYRPVLKKAG--FMTRDARAVERKK--YGRPGARKRFQFCKR-----PGRDRHGNAGWQKPDAV-CDAGAGPGYFCLRMARAVGPRGRVYAIDVEPRDGAADLRRLACR-GRLV-NVDFQA-----GELPVGPPPEHKVCR--EGFL------------EDQPQPAPGRALLVAPDEDWGET--WK------------------------KGLGPMVIGRAFV-----RPCWVDAPVPPGLAEVVLDPGMAFGTGTH--PTTCLCLAG-LCELLAARPGACVLDVGT--GCGFTGPRGVGKTTTARLVALAKVAAEE-------GMRLCPAALALVARQAEGGMRDALCLLREVEKRKILPDPKF----------------QDRIVAKFVNNLMGKKCTGERIIYGAFDQVEAKLKDDPLKVFKKALDNVKPVVEVKCRRVGGATYQVPVEVRQDRRTALAMRWLIDYCR----GRGEKTMVEKLAGEIMDAACNR----GNAVKKREDTHKMAEANK?????????????????????????????????????????????????????????????????????????????????????????????---------------------------MAR-SIKK----GIKTWCRRCTILPDFVGHTFAVHNGRKFVPVFVTENMVGHKLGEFAPTRTFHGHCAEKKAAAAPG---PAKADNCGAKRVMCIKVLG----GTRRKY--ACIGDVIVVCIKEAIPQAKVKKGEVARAVIVRTAREVKRPDGCYIRFDGNCAVLINKD-LE-PIGTRIFGPVARELRARKFMKIICLA???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????-----------------------MATTPINANE-------LELGRRFCFCALVVVGDGAGHVGVGLGKANEVPEAIRKGGDQAKKNLFRVPLVGT----------TIPHEVLGHFGCGRVLLKPAGEGTGVIAGGAVRAVLEAAGVRNVLTKCQG------SRNPHNVLKATVAGLEFVKEKLGQAGICRIEIERA-ANKVKINVHTARPGIVIGKRGAGIETIKKDLQGLTD--NEVYLNVVEV---RKAETDAQLVAENIATQLERRIA-FRRAMKKCVQTALKF-GAKGIRVACCGRLGGCEMARYEWYREGRVPLHTLRAD--IDYGFAEAKTTYGKIGCKVWIMR---GEVLPQ?????????????????????????????????????????????????????HAGTLDPAATGVLAICLEDGVKLQQFLCDGDKAYLTGEIEQVPPMYCAVRTPRRVRVHALELGALGTYVRTLAADLGRAVGVPAHLAALRRTAACGFDLCRA--IGLPMAEALGALAAIRLGEREAWDLVHGRPVP---VRALAPDGRLV?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????LELLRCLCFERRK-VILACGKECYIDCKRTALTAA--VDAFIVRKEPKGTGQW--IEG-RKTLPDGCRVAVIEDVVTTGGCALKAIERCRAEH-MPTICQLVRRGRERL------------QVKKKAPALKEC------PQKRGVCTRVYTTTPKKPNCALRKARVRL-TNGFEVTCYIPGVG--HNLQEHCVVLIRG-------GRVKDLPGVRYHIIRGTLDAVGVQGRKQGRCKYGAKRAC----MKALL-----EAGVHFGHQTKRWNPKMKP--FIFGAR--NGIYIIDLQKTVGLARNALRFVCDCVAKGGCVLFVGTKKQAQDAIREEACRCGQFFVTNRWLGGTLTNEKLEKNLGGIKELCRLPCALFVIDTKKEHIAVHEANRLGIPVVAVVDTNCDPEGIDYVIPGNDDAIRCIRLFTGKVAE-AC---IEGK???????????????????????????????????????????????????????????????????????????????????????????????KYLFVTGGVVCCLGKGLCAACIGALLENRGLEVQHLKLDPYINVDPGTMCPFQHGEVFVTDD--------G-----AETDLDLGHYERFTCAKMTRRNNYTTGRIYQNVIQRERRGEYLGKTVQVIPHITDEIKAVIDILIVEVGGTVGDIECLPFLEAIRQMKYDVGEENAVYAHLTLVPFIAAAGELKTKPTQHCVKELREIGIQPDLLLCRCDREIPRDMKDKIALFCNVDPCAVFTALDVPCIYEVPLCLHREGLHECYKCLNEALVHDAILVPGGFGIRGTEGKILGVKYAREHKVPFFGICLGLQMAVIEMARNVLGLAGANCLEFDEQTPHPVQKGV----TDKGGTMRLGAYPCALKEGTKARALY-GADLVHERHRHRFEFNND-YRAQFEAAG-----MVFC----GVN-PDLGLVEMIEL--PG--Q-HFVGCQFHPEFRCKPFAPHPLFKKFDETVDACINL-GVDPKH-ADQVVRGAVVLPHGMG-KTVRLAVFAKGDKAKEAQEAGADIVGAEDLAEKIQGGFM-------DFDKLIATPDMMGVVGR-L-GKILGPRGLMPVEFRVEKAGIVHVPFGKACFDPEKLKANFCAIMEVIYKAKPQTAKGVYVKNVTLCTTMG--------VARYCE-----SVCRLCRRENLKMYLK-GDRCYTDKCAIERRPYPPGQH-GQ--GRTKFLLEAGFRHAYQNAAAAKGKTGENLLQTLELRLDNVVFRLGFADTRNEARQLVRHGHFKVNGRKVNIPCYLCRPGDKVELVKRPLITEKAERAREACRQYAFEVHRDATKIQVKQAVEKLFNVHVLDVRTKKAYVTLKEGD-----TIALFEG????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????A--ADAAPTAPGTMPA-----LAECATAAQEPAEPAAAGTPAPAAEPCCATAVAGEPLVTIRLMEGQREIAFRPLAPARVLLRGGGELRVGAGARLRVVAREVDNRRALLLVDGDGTEAGARVVVETLRAAHGARATLHGAPLGEADAALTLTVEGEA--GFLVEGD--------AGGALAAVHGVPLEELLRGLVPCE---MPACCPRAALEAQAVTARC---NVLAQIGGGWGH--GAGMCQWGAVG-RA-EAGQMQAPRLEKIVVNMGLGEAINNGKIIDACVEQLAAIT-GQKPVVTRARKCIANFKLRQGQCIGAMVTLRGDRMYEFF-DRLVCIALPRVRDFKGVCPKAFDGKGNYTLGVREQIIFPEINYDKVEKIKGRVNAIIPPIVCIRRFGVTPLRMRDLILICGGTGAGKTTLLNALCAFIPDD-QR--IVTIEDCAELQLQQR--HVVRLETRPP------NIEGKGEILARDLVKNALRMRPDRIVVGEVRGGEVLDMLQAMNTGHE-GCMTTVHANTPRDALARLEAMIGMCGVPLC--EGATRATICRG-------LNVIVQLNRGTDG--RRRIT-------SI-AEITGT--EGAAITMQD?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????AGRVVWEVLEALAAAAAPGATTADLDRLAAARTR-ELGAAPA------FPATLCICVNDEVIHGIPCP--DRVLEEGDLVGLDFGAVLDGWYADCARTLLAVTRAALARGIAAALPGRHTGDVGAAVQRHVEAAGFCVVRDFVGHGIGR-RLHEPPQ-VPNGMVIAIEPMVN--AGGREVETLDDG--AVTRDGCRCAHFEHTVAITENGPEILT-----------------VMCMLRVC-------KIVP-----------------------PKRQIIKDICLCFFHGAKIGLLGLNGAGKCTVLRIMAGVDEEYRLEAIYAAYAEPDADMEKLAEEQAR-LEAIIANAGAD--TGNALEIAADALRLPP-WEAVIKNLCGGEKRRVALCKLLLCKPDMLLLDEPTNHLDAECVEWLEQFLTRFPG-------TVVAVTHDRYFLDNAAEWILELDGIPWKGNYCCWLDQKEQRLEVEAKQECARIKAMKQELEWVRRLLMDKLCFIVPPGAIVGIIGPNGAGKCTLFKMITG--AEQPDC------GF-------VDQCRENLC---SDRTVFEEILCGGERGRLHLAKTLMTGANVLLLDEPCNDLDVE----TLRALEDALLEYAGCVFVICH--------D
Aquifex_aeolicus                                        GAE-VYLTACNPLCT-----QDAIRGEDRETYYKHLRAVIE-----KEPDVVIDDGADLICTLHGGMEETTTGVIRLRAMAEQGVLKFPIIAVNDAYTKHMFDNRYGTGQCTIDGILRATNRLLAGCYFVVAGYGW-CGKGVAQRARGMGAI-VIVTEPIKALEARMDGFLVM-PMEEADFFVTVTGNIHVIRREHFEVMKDGAIVANCGHFNVEIDIPALEEM-AVEKREIRKE-VTE--------YKLKD-GRRIYLLAEGRLVNLAA--AEGHPACVMDMCFCNQVYRVPREIDEAVARLKLNALGIKIDELTEEQKKYLCCW??????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????AIVHIHTTFNNTIVNVTDTQG-NTIAWACGGTVGFKGTRKCTPYAAQLAAQKAMKEAKEHGVQEVEIWVKG---------PGAGRECAVRAVFACGVKVTAIRDVTPIPHNGCRPP---ARRR????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????VVCIEYDPFRCARICLLHYA---DGEKRYIIWPEGLKVGDTVKPLPEIKPGNAMPLKYIPEGTIVHNIEFIPGKGGQIARAAGTWAMPCGEVRMIHERCMATVGRVGLAEHELVKLGKAGRA--RWLGWR---PHTRGTAMNPVDHPHGGGEGRT-RGK-HP------ECPWGWKTKGYKTRRNIGIVAHIDAGKTTTTERILYYTGKTYKIGEVHEGAATMDWMPQEKERGITITVATTACYWTRNGER----YQINIIDTPGHVDFCVEVVRCMKVLDGIVFIFCAVEGVQPQCEANWRWADRFQVPRIAFINKMDRLGADFYRVFKEIEEKLTIKPVAIQIPLLDAVIDYLPCPID-----LPPVKGTNPKTG-EEEVRHPCDDEPFCAYAFKVMCDPYAG-QLTYIRVFCGTLKAGCYVYNATK-DEKQRAGRLLLMHANCREEIQQVCAGEICAVVGLDAA-TGDTEKLEF-PDPVICMAIEPKTKKDQEKLCQVLNKFMKEDPTFRATTDPETGQILIHGMGELHLEIMVD-RMKREYGIEVNVGKPQVAYKETIRKKA--IGEGKFIKQTGGRGQYGHAIIEIEPGGVIPKEFIPCVEKGVKEAMQNGILAGYPVVDVRVRLFDGCYHEV--DCCDIAFQVAGCLAFKDAAKKADPVLLEPIMEVEVETPEKYVGDVIGDLNCRRGKIMGMENKGVI-TVIKAHVPLAEMFG-YATTLRCLTQGRGTFIMKFCHYDEVPDPIADMFCAIKNAIMRRDDFLYV-PCCKLKERILDVLKKEGFIQDWEALKGEYP-IKIYLKYL-DPKKRKC-------AITNIVKVCKGGRRV---YAGVRTMPYVKRGLGIAIVCTDAGVMTDHEARRMRKGGEVIAFVW-------VGLPNVGKCTLFNALTAGLV-KGACKGEGLGNQFLC-HIREVDADKLPPETLEYAKKTLVIRTGYRLLDLITFFTAGERE----ARAFIA-----AEVGKDYEIQD----GD???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DATGKTLGRLACEIAGDF-VIVINAEKIRVTGKKLEQKKYYW-HCRYPGGLKE-RTLKWMLENKPEEVIRLAVKRMLP--KNRLGQQACPAPPVGPALGQHGVNIMEFVKQFNAACRDYEP-GTILP-VVITV--YQDRCFTFIMKTPPVCYLLKKAAGVEK------GCCDPKR-VKVGKITVKQLEEIAKMKMKDMNTRDLKAAMRTVAGTAKCMGIEIEG-------------KVGMTRVLLKDGT----------AIPVTVIKFPVNYVVQVKCQNTKDGYNALQIGAYEGQQLKVEDVFKPGDLVDVWGICKGRGFAGAMKRWDFAGFP-KCHGHR-YHRA-VGAIGQRTDPGRVWKGKRMPGHYGAKPVRVQG------LPEENAILVKGCVPGHNKGIVVVEQCTIG-GVVPELCAREHCFTLTPGLILCLVVGVAFAKALAYEYRKPLVPVHHLEGHIYCVFLEK-----KVEYPFLALIICGGHTDLYLVRDFGRYDF-LGGTLDDAVGEAYDKVAKMLGLGYP----GGPIIDRLAK------EG--KKLYPLPKPLME--EGNLNFCFCGLKTETVVEILLEKCLWAGGVCANCRLREVFKKA-SQEYGFELYIPHPCLCTDNALMIAYAGMERFKRGRIKLRAYDHRLLDQCVKQIIETVKRTGGVVKGPIPLPTRKRKWCVLRCPHK-FDQCREHFEIREFCRILDIIRFTPQTIEALMEICL---PAGVDVEVIKLMLACPEDIRCWCHGEVKRPETLNYRTLKPEKDGLFCAKIFGPIKDGKICEKCGVEVTTCYVRRQRFGHIELAAPVVHIWFLKCTPCKIGTLLNLTCRDVAF-------TKEYYERVREHKKDR----PEWMILEVLPVLPPELRPLVALDGGRFATCDLNDFYRRVINRNNRLKRLIELNAPDIIIRNEKRMLQEAVDALIDNGKRGN------PVKQ---NGRPLKCLADYLKGKQGRFRQNLLGKRVDYCGRCVIVVGPELQMHQCGLPKIMALELFKPFV--------YRRLEEKG---------------YCLEEVVKEHPVLLNRAPTLHRPCIQAFEPVLVEGKAIQLHPLVCPFNADFDGDQMAVHVPLGIEAQLECYILMLC-TQNVLCPAHGKPLT--MPCQDMVLGTYYITGRVLFNCIMPDGYVQGIIT-------NKERYNRINPIYMMAICGARGNRDQIRQLAGMRGLMAKHC-------GEFIET-------------------PIICNFREGLCVLEYFICTYGARKGLADTALKTAFAGYLTRRLVDVAQD??????????????????????????????????????????????????????????????VEGPKGKLELNVHPDIKVTVNQQERW----ITMAALVKNMIKGVTEGFTEVLEIHGLGY--RAQLKGNV----LELHLGKCHPDIYPI--PPDVKIEV---KG-NE-IHIHGIDKQRVGQVAAEIGVDEAGRGPLAGPVVAAAVDCKKLTKKEREEAYEEIDEKCLNCACACIIAKVIRDKIMEIYHKIYPDFNGRLKAEFILARHK-NDCLIPFLEHDDARDCHAVVVAKRGGVVEEVDCCKIIIRDIGIDI-YELRKFQRTNQKTCVNQRPVRKGEKVEKGQIIADGHCTDRGELALGKDVLVAWRGYNFEDAIVICERLVKEDVYTCIHIEELEVEARETKVGEITRQIP---------GV-PERALAHLDE-HGIVRVGTYVKLL----QAIFG-EK--TRDVKDACPPGVEGIVIDVLVKVFIANKRGDKMAGRHGNKGVICVVLPVEDMPFLPNPLGVPCRMGQILETHLG-------WGKTTLYDGRTGEPFDFEVTVGYMHMLKLIHMVDDKIHARATGPYCLVTQQPLGGRAQFGGQRLGEMEVWALEAHGAAYTLQEMLTVKCDDV---------EGECFKVLVRELKALGLNVKCDCGLIVEAICPYPGVYGEVRGEITKEPRGDR-GFGYDPVF-VP-------EGYN-KTMAELCPEEKKEAVARVWLLRDRPNTFIVREYVQRETLYNKIMYPGIYATVRGGGICAQAEAIMYGVAKLRPTLKKAG--LLTRDAREKERKK--YGQMGARAKYRWCKR?????????????????????????????????????????????????????????????????????????????????????????????????????????VFYNPRMRVN--RDDICCKAIEIMKENDLDPFGTPVPFIECVALC-MKRGGILCLTATDTAPLCGTYPKTCMRRYMARPL-RNEFKHEVGIRILIKKVIELAAQYDIAMI--PIFAYCHLHYFKLFFVKERGVEKVDKLIE-QFGFAGPRGVGKTTIARILALKKICEKE-------GIECEEGALEVLAHACEGCMRDAACLLGPVPPREIPPDPKY----------------GDVLVQKLINKVMGKKCVAEWIVYTALEEAAKEVNMHPVELLHKVIEKLKPEWEVRPTRVGGATYQVPIEVPERRQICLAIKWLVQAARERPRGREQYTMIERLKAELLDALNER----GGAYKKKEETHRMAHANMKRVGRGIGCG-HGKTAGRGHKGQKCRCGD---RKMPPY-FEGGQTPL-----YMRIPKRGFKILGDGELTKKFVIKAHAFCKCAKEKIEKAGGKNTLPELEALLEERKLVLENLKKQLKEAHKKELIR----EVRTYCRATTIIPEFVGHTIAVHNGKTFVPVYITQDMVGHKLGEFAPTRTFKGHPE------KTAKVVKKKADNCGAKKVQVIGIPY-----APRKY--ATLGDVVTVTVKEALPQGNAKKGKIYRAIIVRTAKEVRRPDGCYIKFDDNACVLLNQY-GE-PLGTRVLGPIAREVRNKGFTKIACLA???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????-MGGKDIDRLIEE---------------RRKQQNIEEIL-PELGRRFCFCTLVVVGDRKGHVGFGHGKAKEVTLAIAKGIEKAKKNVIRVPIVDG----------TVPHDVIGTFGATKIIVLPARRGTGVVAGGAAKPVFELAGYTDVLTKIIG------STNPDNVVRAVFDALNYIKERYKVAGVCKVEIERI-VDKVRVKIHTARPAIVIGRRGQEVENLKKTLEKMLP-GKEITICVVEV---RVPELDAQLVAQDIATQIERRVC-HRRAMKRAIDNALKA-GAKGVKVQVKGRIGGAELARKEWFLVGRMPLQTLRAD--IDYGFATAYTKYGILCVKVWIYKG--DVLNGR?????????????????????????????????????????????????????HTGTLDPIATGLLIILINKATRFCQFFIGMPKTYFRGEILQTPPPFCAKLKPVKITVYCLEL--LGGYVRCLAYDIGKKLGIGGYMKELRRLKIDEICVEEA--VCLPVDTLFRVIPEVRLNTFEAGKILQGKRILI--VKIYE-DCKFIKALFELK---ELRQKF-IFTLLMFVIYRLGCHIPIPGGRLTVFALGVMPYICACIMMQLLTVAIPCLQRLAKEEGDYGRYKINEYTKTLVA-GTMFLVWIADRITEG-----IGNGACLIIFAGIIIAIIVGIVYVQEAERRIPPIKINPAGVIPIIFTYF--YTAVL-INP-VELAENLHKAGAFIPGVRPGQDTV-KYLERIINRLIFFGALFLCVIALIPILI---SVWFNIPFYF-GGTTALIVVGVALDTFRQIETYLIQKKY-LIKKRCLKVADEPVFKLCCGKLCYVDLKQITFDPPIKP--FVVRKEPKGMKRQ--IEG-LLN--PGERVAVLEDVVTTGCCALKAVKACREYG-MPTFNQLVKYGREKR------------KKKCKAPALQGC------PQKRGVCVRVYTVTPKKPNCALRKARVRL-SNGIEVTAYIPGEG--HNLQEHCIVLVRG-------GRVKDLPGVRYKIIRGALDAAGVEGRRQCRCKYGTKRPKEVVCMKELL-----EAGVHFGHCKCRWNPKMAP--YIYGVR--HGIHIIDLNKTIVMLEDAYHFVCDVIAQGGEILFVGTKKQAKDIIKEEAERCGAFYVNERWVGGLLTNEKLRKLYNGIRDMKKLPDVIWIVDTVREKIAVCEARKLGIPIVAIADCNCDPTVIDYTIPGNDDAIKCIKLLTCKIAD-AV---LEGK???????????????????????????????????????????????????????????????????????????????????????????????KYIFITGGVLCCLGKGITCACIACILEEMGYRVTLQKLDPYLNVDAGTMCPYQHGEVYVTED--------G-----AETDLDLGHYERFTNAVMTRDNNVTAGRIYYNVICKERKGDYLGATVQVIPHITEEIKECIDIVIVEIGGTVGDIEGLPFLEAVRQLCLELGRKNCMFIHLTYVPYIKAAGELKTKPTQHCVKELRAIGIQPDMIICRADRELPKGIKCKIALFTNVKEEAVICAPDLEFCYEVPLKLKEQGLKDCYKCVIEALIHHGIMVPGGFGERGIRGKIEALNFGRENNIPTFGICLGMQLMAIEFARNVLGFCNANCTEFDPDTPFPVQKKV----DKLGGTMRLGAYPCKVKENTLAHRIY-QKDLIYERHRHRYEFNNR-YRKDFECKG-----VVFC----GTC-PDDKLVEIMEL--KN--HMWYLGCQFHPEFKCKPFAPHPLFRRFDETVELAMRL-NVDPRY-ADQMVRGCVVLPHGLG-KPIKVVVFAEGEYAKKAEEAGADYVGGDELINKILKEEWT------DFDVAIATPEMMPKVAK-L-GRILGPRGLMPVEFKVDKAGNVHMPVGKICFEKEKLIDNLYAAIDAVVRAKPPGAKGQYIKNMAVCLTMCMG--------RYIG-----PWVKLDRRFGVVVCGKKC-----APKILARRNYPPGQHGRKYGRRKKLLREKQFKKYFDMACKCKENTGEMLLQYLERRLDNVVYRLGFACTRRQARQLVAHGHVLVNGKKVNIPCYLVEPGDVIEIIIRPIITEKCNRLMEDYNKYTFEVALDACKPEIKYAVEKLFNVKVKKVNTKKAIVTLEKGHKIDILEFAQK--????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????EIDIVDVICEYLNL-------VGCYRTNCPFHPD------DTPCFYVCPCKQIFCKDEKVYVALDR--------VCDFYRECLLKNREACEYVKCRGIDPKVIKEEGFAILVEGYFD------LLRLFC--EGIRNVVAGTA--LTQNQANLLCKFTKKVYILYDGD--------DAGRK------AMKCAIPLLLCAGVEVYPVYLPEGY-DPDEFIKEFGKEELRRLIEYQVDN---LEKLFNNILR-DL-QKCGMQIPRLQKIVVNMGVGEAVQDIRQLERAVEDLRAIT-GQQPVITRARKCEAGFKLRKGMPIGCKVTLRKERMWDFL-DKLICVALPRVKDFKGLCPRCFDGRGNYAFGIAEQIVFPEIDYDKVDRIRGRVNLYKQRALRVIPFDIPEFK--KLILVTGPTGCGKCTTIACIINEINKRLCR-VIITIEDPIEYLFK----DIQCFIAQREVGWDTECFFLGLRAA--------LREDPDIIFVGEIRDTETAKTALHAAETGH-LVFCTLHTLDAVETINRFIGMFPLEH-------RDQIRQMLACTLIAVYCQRLVCKKNGGGKV--------------PV-VEIMIM--TQTIREA--?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????ACQIVAEVLHIVAENVKPGVCTWDLEMIARKETE-KRGAKPA------FPAALCICINDEVVHGLPK--KEKVIKEGDVVCIDFGAIYDGYAGDCAITLLEATKEALYNAIEKALPGKKVGDITKAIHETAEKYGFKTILRYGGHGVGR-KVHQEPF-VPNGMVIAIEPMLC--IGTEETVEDGDG--VKTKDGCLAAHFEHTVAITKKGPVILT-----------------------------------------------------LTFCYDGKHNVLEDVCFYVEKGDFLGIVGPNGAGKCTLLKLILGFLKPK------------------------------------------------------------------------------------YLF------------------------------------------------------GKK-----------------------------------------------------------------------------------------Y-------VPQRL-SVEHA-FPGTVKELLLCGGQQQRVLLAMALCYNPELILLDEPTVGLDVHAINHFMCILLDLNMNHKKCIVMICH--------D
Archaeoglobus_fulgidus_strain_DSM_4304                  GAE-VAITGCNPMCT-----QDAKRGMDVEEYYEALRNVIR-----AEPDIVIDDGADLIFLLHGACEETTTGVIRLRAMEREGVLKFPVIAVNDAYTKYLFDNRYGTGQCAIDGVIRATNLLMAGKIVVVAGYGW-CGRGIAMRARGMGAC-VVVTEEIRALEAVMDGFRVM-RMEDADIFITATGNRDIIREEHIRLMKDGAILANAGHFNVEIDIPALERM-AKAKREARKY-VTE--------YDLGD--KRVYLLAEGRLVNLVA--ADGHPVEVMDMCFANQVYRLPEELDRMVARMKLECMGVEIDQLTEEQVRYLCDWDIGGLKRELRLVREMIE-LPLKHPELFQRLGIEPPKGVLLYGPPGTGKTLIAKAVANEV-----DAHFIPICGPEIMCKYYGECEQRLREIFEEAKENAP------SIIFIDEIDCIAPKREEVTGEVERRVVAQLLALMDGLEARG------DVIVIAATNRPDAIDPALRRPGRFDREIEIGVPDKEGRKEILGADLEALCKEAAMHALRGPPGTGKTLLAKA---VANECNANFICVKGP--ELLCKWVDEIDCLAPRRGGI-GDCHVTERVVCQLLTELDG--LEELKDVVVIAATNRPDMIDPALLRPGRLERGIAHIYCCYNNTIITITDITGAEIIARVCGGMIVKADRDEGNPYTAMQAALRAAAIAKEKGIDGVHIKVRAPGGN-KHTTPGPGAQAAIRALARAGLKIGRIEDVTPIPHDGTRPPGGKRGRRRCAGRFGPRYGLRVRRTWLEIEAVQRQKYVCKKCGK-KAVKRCGTGIWECRHCGYKFAGGCYQPVDEGALKFVMNGADVMKPGIVYADERIKEGDFVGKAVKNIHHIKDYAYIREAWKRPYE-GYVGELMWHRLQKWRREPAVVRIPRPTRLDRARALGYKAKKGIIVVRVRIRRGGRRATRPNKGRKCKGLMVNRRTP-KKNLQWIAEERANRKYPNMEVLNCYWVGEDGRYKWFEVILVDRDHPAIKCDPQLCWVC--RTRGRVYRGLTCAGRKARGLVIDIQHDCARNGPVALVKLP---DGCETYILAVEGLGTGDVVGDNVEIACGNITYLKNIPEGTPVCNIEAQPGDGGKFIRACGTFGMPCGKQKWFHPNCRAMIGVVAGGGRTDKPFVKAGKKYHKMKCKAAKWPRVRGVAMNAVDHPFGGGKHQH-VG--KPKTVCR-NAPPGRKVGCIAARRNIGIVAHIDHGKTTLCDNLLAGAGMICE--ELAGQQLYLDFDEQEQERGITINAANVCMVHEYEGQD----YLINLIDTPGHVDFGGDVTRAMRAVDGVIVVVDAVEGVMPQTETVLRQALKENVKPVLFVNKVDRLIKELELTPQQMQERLIKVITEVNKLILDMVIRHLPCPIEAQKERIAVIWKGDINCEVGKAMVNCDPKGPVALMITKIVVEPQAG-EIAVGRLYCGTIRPGMELYIVDR-KAKNRIQTVGLYMGPRRVEVDEIPAGNIVAVIGLKDAVAGCTECIKHYCEPVVTMAIEAKNPRDLPKLIEVLRKLAKEDPTLHITLNEETGEHLICGMGELHLEVKVE-KIRRDYKLDVITCPPIVVFRETVTGTC-PVVEGK------SPNKHNRFYIVVEPGIQYLNETMELILEGFREAMRAGPIAREPCMGIKVKLVDCKLHEDAVHRGPAQVIPAVRCAIFAAILQAKPALLEPYQKIFITVPQDMMGAVTREIQGRRGQILEMKTEGDM-VTIIAKAPVKEMFG-FAGAIRGATCGKAIWCTEHAGFELVPDTLCNAMIAIKNAEMVGEKKCEIKPACKLIGNVLKVMKDYGYIKGFEYVE-NGK-FIVELCGN---INDCG-------AIRPRFCCCVTEYEM---YEK-RYLP--ARDFGILIVCTTKGVMCQKDARKQRLGGVLLAYVYGDATAVLIGYPCVGKCTLLNKLTPGII-EGAACGRGRGKEVIC-AVRVADLK-------EYKIHCALKEQIYRKLEFIRVYLKPPGGKVDFCEPFRY-----AKVGLEHVVED----GDMATVYDVPADLLIKRVAERLKDM---VAPPEWAKYVKTGVHKERCPEQD-D-WWYLRLACIFRRVYIDG-PVGIERLRTFYGGRKR--RG--SKPPKFRKGCGAIVRNALHQLEQLGFVKKTRE---GRVVTPMGRCFLDKVADACGHILGRLCCKIAGER-IVVVNAEKAVITGDKYMVFERYK-EKYDRGC----KEKGPYFPRHPERIFKRTVRGMLPW-KCCRGGQACPGPPLGPAIGPLGLNVKQVVDKINEATKDYE--GLCVP-VKIIV--KDDRCFEIEVGIPPVCALIKRELGIEK------GACNPGR-EVVGNLTMEQLLNIARIKRQQCLCYTLKEVVKEVLGTCNCMGITVEGKCPKELTRMIEEGKAGMTHVVMIDDRKNCPTYGEEVVVPVTVIETPPMKVAAVRV-YKKTQYG--MQIAAEGKEICVCEVFDEGAIIDVIAVTKGKGFQGPVKRWGVITLD-AKHARCCKHRR-VGNLGP-WNPHHVRWTVPQAGQMGFHQRTEYNGFLHYGVIRTQYVLVTGCVPGPVKRLIRMRDAIRG-GIHPREACQHHAFCQGPGMGPCLRVVATAARLLAIKLEKPLVGVNHCLAHVEVGRWQT-----GARKP-VCLYVCGGNCQVIARRG-NRYRV-FGETLDIGIGNALDKLARHMGLKHP----GGPKIEELAK------KG--QKYHFLPYVVKG-----MDFCFCGMVTETAFAMLTEVTERAGGVAANKRLQEMLRIM-CEDRGAKFYVPPKELAGDNGAMIAYTGLLMYKHGRIKLCGLNPRELDRICCQIKEIANKTGVELCGPVPLPTRRMVVPVRKAPDGEGCETWDHWEMRVHKRLIDI-SADERALRQIMRIQV---PRDVNIEIIKFEVLCPQEIRRMCVVKIITPETYDDDGF-PIDGGLMDTRL-GVIDPGLRCKTCGGKAGEC---PGHFGHVELAAPVIHVGYAK----MIARLLNGTCCECPH-------CREWLEKIPD--DDR----PEWFVLTVLPVPPVTVRPCIILETGQRCEDDLTHKLVDIIRINQRFMENKEAGAPQQILEDLWELLQYHVTTYIDNEVCGI------PPARHR-SGRPLKTLAQRLKGKEGRFRGCLCGKRVNFCARTVICPDPCLCINEVGVPREIAEELTVPIYVTPQNIDMAREFVLRC--EHP-------KANYVERQLMDGDIVLFNRQPCLHRMCIMAHYVRVLPYKTFRLNPAVCPYNADFDGDEMNLHVPQCLEAQAEAKILMAV-QEHILCPRFGGPII--GGIHDHICGLYLLTGKEIFCFILPDGYRRGDLEPMPGRCIEETLEMRINAAVIMAVCGARGCMLNLTQMAACIGQQCVR--------GERICRGRTLCHFKPGDL-GAEARGFVRCCYKKGLCPVEFFFHAAGGREGLVDTAVRTCQCGYLQRRMINALQDMGC--VMMKIRVMPCDVDVDLNEVQ-PIAFGLKAIVLMAVMPDME-GIGDRYIEEIGKIEGVAVGPKGENTRYLKYR-GVFIEVGDGK----VTFAGHIENLITGVKEGFEYHLKVVYAHFPIKVRVEGNE--VIIENFIGEKHPRRAKIV-G-RAQVEI---SG-QD-IYVRGIDIEECGQTAANLGIDEAGKGCVIGPLVVAGVDCKKLCQGRREELAEEIDEKYPLVAAACIIAKVEREREIERLKE---KFGGRARRPLIVVK---DGGLIEYLDAEEGICTGCIPYAEHNACPRNTMGAAMIKQGIPYCN-LAWRTDTRGHLMQH-PQVPVTTDTQVEIK--FDERPA--------GQNFVVAYEGYNIEDALIMNKGCVERGLGRCFFYRTYECEEMRYPGGD-KFEIP--GADIC--GFRGAEAYAHLDE-DGLIFPETEVRFL--EEPTELG-IC--PQKRRETCRCNEKGVVDAVLAKVRVRDLRGDKFACRHGQKGVVGLLVPEEDMPFTENPHAIPCRMGHVLEMIGG-------KGKEVMYDGITGRRYLVDIFVGVIYYQKLYHMVCCKIHARCRGPVQVLTRQPTEGRARKGGLRFGEMERDVLIGHGAALLLKDRLLEECDKVEVWVCGN--CGYAFKLLLDELKCMMIAPRIDCGLFVEALKGFPGPYGKVEGEICREMRGTQ-GFGYDPIF-LY--------GN--KTFAEMATEEKKTATARAVIKPGKGRVRINEIHQP-ELARMKIMEPDIEVKTWGGGFMAQAEAARTAIARLRKAFLEYDRTLLVNDVRRKLPKI--QGGRGARARRQTCYRTKCKYGCH--YGEREWVPWRCKLLYLGAACGTTVCHLADIV-DEGIIYAVEYCAKIAQKNQIEILKANGEVV--IMVKA-----RCIDCTAEPEEVFKC-VLKEMVFYNPRMRFC--RDDVCPKAVKVIEENDIDPFGCPAPFMDCACFC-AKR--YLCVTATDTAALCGCATNCGLKKYGAFAV-KTDVYHEVGLRMLIGFVVREATKYEKALF--PLICWVREHYYRVHFKIKKCTAMCAKVYE-KMGLAGPPGVGKTCLALALALERIALKE-------GIKVDKCVLLKIAENAGGDLRAAINDFDPALECYICLEPKYVPHNHGRHANVPFAKQKVFIVERLINKVMGKKILAYNIVKEAFEIIEKKTKKNPIQVLVDAIINAGPREEVVRLKYGGIAVPKAVDTCCCRRVDIALRNIAEGARRAA-FKCKRCIAQCLADEIIAAANNE-SR-SFAVAKKEEVERVAKCARRG-SRTFGWGCHKNRRGRGNRGGAGNAGV---HKHKYI-KFVKLAKK--GEYLFG--KHGFKLLGCGKVTRKMEVKVFEATPKAVEKIEAAGGGYTLEELQ------KMPLEELAKLLPARERRKIKR----GARTHCRDMVVLPEMVGKVVFVHNGKEFVRVEIKPEMIGHRLGEFALTRRFEKHCGPGVGATRCCKYVPLKADNTGARELEIIAVKG-Y-KGVRRRYPAAGVGDIVVVTVKKGTPE---IRKQVHYAVIVRQRKEYRRPDGTRVKFEDNAAVITNER-GE-PRGCEIRGAVAREAAER-FCKIGTIARLAACVLKCGENRVWF--DPAALEDIATAATKQDIRELIEQGVIKRKPVNGVCRARINKRKLQKR-KGRRRGHGCRKGAKGARM-PRKRMWILRIRALRKALRQMKAEGV-VDRRTYRILYRKAKGGEFRCVAHLWVPKTKLGRLVADGKIKTMDEALACNLPLKEPEIVDILL-PDLGRRTKFRVTAVVGNRNGYVGIGTGKACQVAPAIQKAINNAKLNIFKVQRGCGCWECGCGGDHCLPFKVTGTCGCVRVTLIPGPKGLGIVAGDVAKRVIELAGVKDVWCFTKG-----QTKTTVNFAKATYEALEWIKDEVRCAGFGGVDILRT-PLGTQVTLFVERPGLVIGKGGRRIKALTEKL-KDFG-IENPQVCVDEV---EKPEFNAQLMACLLARALERGWY-FRRAGYRFLYRIMEA-GAKGCEIEICGKLVC-ERARTEKFVAGTIVHTGDPAECMVQKGFDIAIKKLGVLGVCVRIIPP--DVTLPDLRAILEPEAKERLCRLKLAHPEIAEAVENQLIYLAQAGRIQCKITDKMLVEILHAGTLDPRVTGVLPIFIENATKMVKFLQECCKEYFVGRIYQRPPLKCAVKVLRIREIYEMEL--LGTYIRKLCRDIGEVLGTGAHMQELRRTRTGKFGEDMC--YTLPMEVAAAELPKIVIKDCAVDAICHGANLCVRGVAIFTLKNELVPCVERPKGHVHFREKF-GWTAAILLLYFILCNVPVFGG--SIIALGIGPIVTACIILQLLVGA--GIIKLDLTN-PEDRAAYQDFQRQLFI-GGVLIVYMDEVVCKG-----IGCGVCLFILAGITAAIILLVVFFEGTRVEIPPIKLIYACVLPMIFAWF--WVETCGMDA-RTVACQIAKCGMQVPGFRKCPQVLERVLCRYIPKVTILGGAIIGILTLVANML---GTIGNV-----SGTGLLLAVCIAYRFYEDLAKEQLTEMHPMIEVGALKFGD---FVLCCGKRCYVDVKLACTFPP--L--VIFRKEKKGIKGD--RIG-EVK--EGEKVVVVEDVITTGCCALCAARRVEECGGLFAARKLMENRKKFRWCDRRFVRRTL-GLAAKADPLEGA------PMARGIVLEKIGIEARQPNCAIRKVRVQLIKNGRQITAFCPGDGAINFIDEHDEVIVEKIGGRMG-RCMGDIPGVRYKVVK--VNNTCLRELVRGR----KEKRLRLVPPDDYL-----AAGVHIGTQIK--TGDMKK--FIFKVRQ-DGLYVLDIRKLDERIRVAAKFLCRY--EPCKILLVAARQYAHKPVQMFCKVVGCDYIVGRFIPGTLTNPMLCEYRE--------PEVVFVNDPAIDKQAVCEATAVGIPVVALCDCNNCCADVDLVIPTNNKGRRALAIVYWLLAR-EI---AKIRKQVIVVRDDLKLCRGKLAVQVAHAWLDEGQKKVVLKVKCLEELLGIKHKAECLGLVTGLVQDAGLTEVPPGTITAVVIGPDEERKIDKVTGNLPLKYIVVTGGVMCGLGKGITAACIGRLFVDMGYRVIPIKIDPYINIDAGTMNPFQHGEVYVLKD--------G-----TEVDLDLGHYERFIGEEVTGDHNITTGKIYKRVIEKERKGDYLGQTVQIIPHVTDEIKCWIEICLVEIGGTVGDIEGMPFLEAIRQMHNEEKEEDFALVHVTLVP-LDAGGEQKTKPTQHCVKELRELGLHPDVIVGRCCERLKPATKKKIALFCDVPEEAVICNEDAEDIYEVPLIFKREKVRDAYLCIKEALKHDGILVPGGFGARGAEGKIRAIEYARENGVPFLGICFGFQLAVIEFARNVVGFCEANCTELDENTPHPVQKGI----DEMGGTMRLGDIEVTIKPGTIAHKLY-GCEKVVERHRHRYEVNPE-YIEKIECKG-----LVFC----AYC-DGGRRMEIAEL--PD--HPFFFATQFHPEFKCRPYRPCPPFRRFVETVEMAVNLRNVDMKK-PENRIDTVVNLPHGLG-KPRKIGVFAKGDTALKAKEAGADVVITPEEIDELAKDKRRAKKLANCIDFFIAEAPLMPEIGRKL-GPVLGPRGKIPVKIRTRDKTTFHAPIGCENMDVEKIAENAMEILKVVENKYENPTQ--VVKCVYVKKTMGMGDPKRH-RKKYTT--PTHPWDKARLEKEMQLVIKYGLR---NKRELWRFQNILRKY-RR--VARDLLNKMGIL---PENATLDDILNLCVEDFLERRLQTMVYRQGLARTIKQARQFITHGHIAVDGRRVTCPCFIVTKELECKIIKCFLVTEKCVAELE-KNVLTAIVDMRARKEHIKKEIEKLFNVEVERVNTKKAYIKLKPDY--SAEEILCKLGVLNLKGEVTEEIEL-PEVFAEEFRPDIIKRAVLALQCHRRQPYGPNPLCGVDYCW------ENWGP--GHGYARVP-R--WKLGR-----R-AVVVPQAVGGRRAHPPKPERKWAEKINKKEMRKALKCAIAATANEELVRQRCHVFEG--EL--PKVVCNELEC-VKRTKDVAEVFRAIGVYADVERAKERK-RYRAGRGKMRGRRYVKKKCVLLVNLPGVDAVVVKDLNVELLAPGCHPGRLTVWTKCAARLRKGGEEFEVLVDPYLARDLK--EGK-E-VNFEDLLAAEEVFKDAKKGERACVDELRKIFGTDDVFEIARKIILEGEVQITAEQRREMLEAKRKQIINFICRNTIDPR-TNAPHPPCRIERALEEAKVHIDIFKCVEAQVKDIVKALKPILPLKFEEMEIAIKIPPEHTGRAICALYNFG--GVTREEWQRDGCWICVM-RIPCGMYGDLMDLLGKVAKGVCKIKEGTVIDHINAGKA--------LLVLKILKIQP-GTDLT--VCMAMNVPCCKMG-K-KDIVKVEGMFIRDEELNKIALICPNATINLIRDYEIERKFKVCPPEVVEGV--LKCPNHACICNAER-EPITPKFYIK-TEEMRATARCHYCCNPNLVTLIDVLLCECAKNEAPVWKEVAERLAKPRRLQA--EVNVCKIEKYAKPN-----EYVVVPGKVLGCGCITKP-VKVAALCFCEKAACKIREAGGVC--MKIEELLK--ENPKGCGVRLPIRCFCCGAVIGHLYDEYKQKL--SEGK---SP-----KEALDELGIERYCCRRMFITHLREGGYVVI------DDEPCEILCICVCKPGKHGAAKARIDAIGIFDCQKRCIVQPVTAKIYVPIVERKRAQIQLMDLETYETGREVIYLEC-LGKRKIKYLIHAEIEAEGVVDV-----VGAFGQTEGLLGGDL----DLRELQKTGRIGRIA---AALETIER--------VGPCCAKIKVLKIEDVRACKRKRIVERAIDECDAIIVVEGRAD------VLNLLK--HGIKNVIAGTN--IPKTIVELCKKKTV--TAFLDGD--------RGGDL------ILKELLQV-AEVD---YVARAPEGK-EVEDLTQKE----ILKCLDLAAKK--EFDYIVGVRLG-SV-VKVPMREVVLDKVVINIGVGEC---GERHKKAYCLLEELV-EQKPAITYAKMTIKNFGIRKGEAIGIKVTLRGEKALKFL-KDALT--VK---ENR-LCRKCIGE-GYFAFGIAEHIDLPGVDYDPDVGIFGRIAIAERPEITAVRP-IAQVCIDEYILICGPPGAGKCTFAACVANFLLEN-GY-IVKTMECPRDLMVRD---EITQYAPLEG------DMCLTCDIL--------LLVRPDYTIYDELRRTCDFQVFADMRLAGV-GMIGVTHATRAVDAIQRMIGRVELGMIPQV---VDTVVFIDAGRIVKVYELCFTVKVPTGMTE--ADLAR-------PV-IEVRDF--ETKNLEY-EGRCRRKPCGG-FYRKARK-KRKYELGREQVETLIG--ER--KVKKIRVRGGNYKLKLFADKYANVYDPKQGKVVRVEIECVVENPAHVHYARRNVITKGAIIATCIGKARVTNRPCQEGVVNAVLAGKILKQAVNEAAEKIAPGVKILEVAEFVENRII-ELGAKPA------FP--ANICINCDAAHFTPKKNDERTFKEGDVVKLDVGAHIDGYIADMAVTLVKAAKEALEAAMEVVRAGVCVCEIGKAIEDAITNYGFKPIVNLTGHGLLPYLNHAPPC-IYNGMVVAIEPFAT--NGVGKVGERGECEILTEVCGGLVCQWEHTLIVEDGGATITTCQ-PKKCG-QECVKYCPICENLCVG--CGICVKKCPMHAIWIVGLPEELEGR-EVHRYGKNGFVLYNLPV-PRKGYVVGILGPNGTGKCTAIKILCGQLKPNKPQ-----YIEA---IPKVY--SGK-AIELLKRVDER---G-MLDAVVEKLGLAEAIKRDVKDLCGGELQRLAIAACILRDADFYFFDEVTCYLDIYQRIAVAGVIRELAA-----EKTVMIVEHDLAILDMLADFVHITYGTP--GVFGVVTNAKGARVGINQYLRG----YLAEENIRIRFRLEVEGGE-IYQGEVLGVVGCNATGKCTFVKVLAG--VIEDDE------KY-------KPQYV-KAD---VNMQVGMFLLCGGELQRVAIVACLLREADLYLLDEPCAHLDVEQRTEAARVIRRFALNTGKCVLVVDH--------D
Bacillus_subtilis                                       GLA-VILIGDDPACHCYVRGKKDC-SLTEAELLCIIDQYNQ------DPEF---HGILVQLPLP-SPDKDVDGFHPLNV----GKMLLGE------------DTFLPCTPHGIVELLKKTNIDLCGKEVVVVGRCNIVGKPVGQ---------LLLNETVTYCHCRTENI------TEHDILVVAVGRANFICADQI---KEGAVVIDVG----------------------------------------------VNRLENGKLCG--------------DVEFEGATITMLAHNTVKCAKRTLC--------------------QYIGQHKVKENLRVFIDAAKMRQ---------ETLDHVLLYGPPGLGKTTLACIVANEM-----GVELRTTCGPAIERP--GDLAAILTA-LEPGD-----------VLFIDEIHRLHRCIEEVLYPAMEDFCLDIV-IGKGPCARCVRLDLPPFTLVGATTRVGLLTAPLR--------------DRFGVMCRLEVEID---KPCALEIARGTPRVANRLLRRV---------RDFAQVLGD--SRITEDIDR-------LGLDHIDHKLLMGMIEKFNGGPVG--LDTICATIGEECHTIEDVYEPYLLQIGFIQRGIAHIRCTFNNTIVTITDTHG-NAICWCCAGALGFRGCRKCTPFAAQMAAETAAKGCIEHGLKTLEVTVKG---------PGCGREAAIRALQAAGLEVTAIRDVTPVPHNGCRPP---KRRR????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????VATVEYDPNRCANIALINYA---DGEKRYILAPKGIQVGTEIGPEADIKVGNALPLINIPVGTVVHNIELKPGKGGQLVRCAGTCALNCGEVRMILCACRACIGQVGNEQHELINIGKAGRC--RWKGIR---PTVRGCVMNPNDHPHGGGEGRAPIGRKCP------MCPWGKPTLEFKTRRNIGIMAHIDAGKTTTTERILFYTGRIHKIGETHEGACQMDWMEQEQERGITITCAATTAQW----KG----YRVNIIDTPGHVDFTVEVERCLRVLDGAVAVLDAQCGVEPQTETVWRQATTYGVPRIVFVNKMDKIGADFLYCVGTLRDRLQANAHAIQLPILDAVLDYLPAPTD-----VAAIKGTRPDTN-EEIERHCCDEEPFCALAFKVMTDPYVG-KLTFFRVYCGTLDCGCYVKNCTK-GKRERVGRILQMHANCREEICTVYAGDIAAAVGLKDTTTGDTECMEF-PEPVIDVAIEPKCKADQDKMGIALAKLAEEDPTFRTQTNPETGQTIICGMGELHLDIIVD-RMKREFKVEANVGAPQVAYRETFRTGA--KVEGKFVRQCGGRGQFGHVWIEFEPGGVVPREYIPAVQAGLEDALENGVLAGFPLIDIKAKLFDGCYHDV--DCNEMAFKVAACMALKNAVCKCNPVLLEPIMKVEVVIPEEYMGDIMGDITCRRGRVEGMEARGNA-QVVRAMVPLAEMFG-YATALRCNTQGRGTFTMHMDHYGEVPDPIADMLTRIRNANMVRHEKLEI-PACKLKREIPEILKREGFIRDVEFVE-DGI-IRVCLKYG---QNNER-------VITGLKRICKPGLRV---YAKCNEVPRVLNGLGIAIICTCQGVLTDKEARAKQAGGEVLAYVWRGEVVAIIGPCGCGKCTLLRCLN---------AEKFTRKEAHR-LRQQTA---------EHKADCYADQVIFMADG------------------FIK--------GEP---------AE???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DAAGKTLGRLCCEVAGDH-VIIINAEKIELTGKKLTDKIYYR-HTQHPGGLKC-RTALEMRTNYPEKMLELAIKGMLP--KGCLGGKANPAPPVGPALGQAGVNVMGFCKEFNARTADQA--GLIIP-VEICV--YEDRCFTFITKTPPAAVLLKKAAGIEC------GCGEPNR-NKVATVKRDKVREIAETKMPDLNAADVEAAMRMVEGTARCMGIVIED-------------KIGMTQVFAENGD----------LIPVTVIEAAPNVVLQKKT-AENDGYEAIQLGFDDGQEVKV-EIFCAGEIVDVTGVCKGKGFQGAIKRHGQCRGP-MCHGCR-YHRR-PGCMGP-VDPNRVFKGKLLPGRMGGEQITVQN------DAERNLLLIKGNVPGAKKCLITVKCAVKG-GVVPEIACRHHAVTEGPGLVGALLIGVNAAKALCFAYNIPLVGVHHIAGHIYANRLVE-----DIVFPALALVVCGGHTELVYMKEHGCFEV-IGETLDDAAGEAYDKVARTMGLPYP----GGPQIDKLAE------KG--NDNIPLPRAWLE--EGCYNFCFCGLKCNCVIDVLVTKTARAGGVAANRGLRAALEKEFAQHEGITLVIPPLALCTDNAAMIAAAGTIAFEKGRIRLKAYDHRILDQCAEKIVETAKRCGACVCGPIPLPTEKCVYTILRAVHK-YKDCREQFEMRTHKRLIDIVNPTPQTVDALMRLDL---PCGVDIEIMNIGLACPDKIRCWCFGEVKKPETINYRTLKPEKDGLFCERIFGPTKDGVVCDRCGVEVTRAKVRRERMGHIELAAPVCHIWYFKGIPCRMGLVLDMCPRALDK-------YKTCQGQRRT--RAK----PCWMILDVLPVIPPELRPMVQLDGGRFATCDLNDLYRRVINRNNRLKRLLDLGAPCIIVQNEKRMLQEAVDALIDNGRRGR------PVTGP--GNRPLKCLCHMLKGKQGRFRQNLLGKRVDYCGRCVIVVGPHLKMYQCGLPKEMALELFKPFV--------MKELVEKGLAH-------------VLECVIKEHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVCAYNADFDGDQMAVHVPLCAEAQAEARILMLA-AQNILNPKDGKPVV--TPCQDMVLGNYYLTGKLVFNEILPDGFRRGLIT-------EEERYERVNPIYMMCDCGARGNACNFTQLAGMRGLMANP--------AGRIIEL------------------PIKCCFREGLTVLEYFICTPGARKGLADTALKTADCGYLTRRLVDVAQD??????????????????????????????????????????????????????????????VKGPKGELTRTFHP--DMEIKVEDNV----LTTRCLLGNMVEGVCKGFERGLELVGVGY--RACKCGNK--LVLNV--GYCHPVEIVP--EEGIEIEV---PCQTK-VVVKGTDKERVGAIAANIGVDEVGRGPLAGPVVACAVDCKKLCEKKREEYYELIDAKCVCIAAGACIAKVTRDRMMCAYAETYPMYGGAFIDDCIVARF--RGACIPFLENDDGKDCGAAVICKHPGIVERVEAKNVWVRKGNLDK-YCLLKFVRCNQGTCYNQRPVCVGDEVVKGEILADGPCMELGELALGRNVMVGWDGYNYEDAIIMCERLVKDDVYTCIHIEEYECEARDTKLGEITRDIP----------NVGEDALRNLDD-RGIIRIGAEVRLL----HAIFG-EK--AREVRDTCPHGGGGIIHDVLVRVYIVQKRGDKMAGRHGNKGVICKILPEEDMPYLPNPLGVPCRMGQVLELHMG-------MAKTVLYDGRTGEPFDNRVCVGIMYMIKLAHMVDDKLHARCTGPYCLVTQQPLGGKAQFGGHGFGEMEVWALEAYGAAYTLQEILTVKCDDV---------VGECFKVLIKELQCLGMDVKIDCGLCIDNLGGRPGVYGHVEGYIAEEPRGEY-GFGYDPIF-IV-------KDKD-KTMAELTCDEKKCCVARVRLVPGEGRIVVNCEHIPCAALIEDIKQPDVLVNVHGGGLCGQAGAIRHGIARYRTTLKRAG--LLTRDARMKERKK--YGLKGARRAPQFCKR?????????????????????????????????????????????????????????????????????????????????????????????????????????LCIHTTHEAV--EPDYPDEGV-IVKAYNEEEWATA--WK------------------------KYYHPVKICEKFTIVPT-WEEYTPVHTDELIIE--MDPGMAFGTGTH--PTTVLCIQAHER---FVQKGDKVIDVGT--GCGLYGPPGIGKTCIATAIALERALHDEHRGLGTYCVCIDDQAMEHFAHGCGGDVRCALNALGPVAKRDVLPDPIY----------------NCKLVCRLINKMMGKKGKPQTILYKCFDIIKERTGNDAMEVFEQALKNIMPVLEVKARRVGGANYQVPVEVRPERRTTLGLRWLVNYAR----LRGEKTMEERLANEILDAANNT----GAAVKKREDTHKMAEANK?????????????????????????????????????????????????????????????????????????????????????????????---------------------------MAR-SLKK----GVKTWCRRCTIFPQFIGHTIAVYDGRKHVPVFICEDMVGHKLGEFAPTRTYKGHACDDKKTRR--------ADNCGAREVLTIKVLG----GCGRKT--ANIGDVIVCTVKQATPGGVVKKGEVVKAVIVRTKCGARRCDGCYICFDENACVIIRDD-KC-PRGTRIFGPVARELRENNFMKIVCLA???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????--------------------------MRRIDPCK------LELGRRFRFAALVVVGDKNGHVGFGTGKAQEVPEAIRKAVEDAKKNLIEVPMVGT----------TIPHEIIGRFGAGNILLKPACEGTGVIAGGPVRAVLELAGVADILCKCLG------SNTPINMIRATLQGLEYICKRLCDACVCKVEIERA-ANRVNITIHTAKPGMVIGKGGCEVEALRKALNCLTG--KRVHINILEI---KRADLDAQLVADNIARQLENRVC-FRRAQKQQIQRTMRA-GAQGVKTMVCGRLGGADIARPEYYCEGTVPLHTLRAD--IDYATCEADTTYGKLGVKVWIYRG--E-VLPT?????????????????????????????????????????????????????HTGTLDPEVCGVLPICVGRATKIVEYLTEKCKTYLKGKQEQIPPMYCAVRPKRMITIEDIAL-TTGTYVRTLAVMIGEKLGYPAHMCHLIRTACGDFCLDEC--FTFPIERALNHLPKWIICDTLAKKVENGALLETPEIAVFTECGTCL?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????LLDIQAVFLRPNEPFTWACGILCYCDNRLTLCFPP--M--CYVRCKPKGKGNQ--IEG-AVQ--EGQKTVVIEDLICTGGCVLEACAALQAAG-MPTINQLIRKGRVCKVENCKCP-----ALNKGYNCFKKEHTNVCCPQKRGVCTRVGTMTPKKPNCALRKARVRL-TNGIEVTAYIPGIG--HNLQEHCVVLIRG-------GRVKNLPRVRYHIVRGALDTAGVENRAQGRPKYGTKKPKAVICMKQLL-----EAGVHFGHQTRRWNPKMKR--YIFTER--NGIYIIDLQKTVKKVEEAYNFTKNLAAEGGKILFVGTKKQAQDCVKEEAQRCGMYYVNQRWLGGTLTNERLEKFLGGIKDMKDLPDALFIIDPRKERIAVAEARKLNIPIIGIVDTNCDPDEIDVVIPANDDAIRAVKLLTCKMAD-AI---LEAK???????????????????????????????????????????????????????????????????????????????????????????????KYIFVTGGVVCCLGKGIVAACLGRLLKNRGLNVTIQKFDPYINVDPGTMCPYQHGEVFVTDD--------G-----AETDLDLGHYERFIDINLNKFCNVTTGKIYCTVLKKERRGDYLGGTVQVIPHITNELKDRVDVVITEIGGTVGDIECLPFLEAIRQMKCDIGRENVMYIHCTLVPYIKAAGELKTKPTQHCVKELRCLGIQPNIIVVRTEMPICQDMKDKIALFCDIDTKAVIECEDADNLYCIPLELQKQGLPDAYICVVECLRHDGIIVPGGFGDRGVEGKIVATKYARENNIPFLGICLGMQVACIEYARNVLGLKGAHCAEIDPCTQYPIQKDV----EDLGGTLRLGLYPCKLEEGTKAFEVY-QDEVVYERHRHRYEFNNE-FRQQMEEQG-----FVFC----GTC-PDGRLVEIIEL--KD--HPWFVACQFHPEFKCRPTRPQPLFAKFDATVEVAFRL-GVDPCK-NHQQIRGAVVLPNGTG-KTQRVLVFAKGEKAKEAEAAGADFVGDTDYINKIQQGWF-------DFDVIVATPDMMGEVGK-I-GRVLGPKGLMPVEYRVDKAGNIHVPIGKVCFEDEKLVENFTTMYDTILKAKPAAAKGVYVKNVAVTCTMGMA--------RYTG--P--SW---------KLCRRLGICLCGTGKELEKRPYAPGPHGPG--QRKKLVNERQFRTLFDKAGKLAGKHGENFMILLDCRLDNVVYKLGLARTRRQARQLVNHGHILVDGCRVDIPCYLVKPGQTIGVLKRPVITERCADLMT-EEKYTFEVDVRANKTEAKDAVECIFGVKVDKVNIRKAIVKLTADC--KEIEIFEA--LYNQNGCTAGDIELNACVFGIEPNECVVFDAILMQRACLRQ--------GTHKVK------NRCEV---RGGGRKPWR--QKGTGRAR--QGCIRCPQWRGGGVVFGPTP-RCYCYKLPKKVRRLAIKCVLCC-----------KVIDN------NIIVLEDLTLDTAKTKEMAAILKGLCV----------------------------EKKALIVNIPGVTVVEANGINVLDVVNH---EKL-LITKAA??????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????MQVPKIEKIVINMGVGDAVQNAKAIDCAVEELTFIA-GQKPVVTRAKKCIAGFRLREGMPIGAKVTLRGERMYDFL-DKLICVCLPRVRDFRGVCKKCFDGRGNYTLGIKEQLIFPEIDYDKVTKVRGQVGFKKKDCICARMQKKKGTADEEHVIIDGRIA---------------------------------------DICQTGFLEG-----------------------VIVIPQF-VLEELQ-----------------------HIADCCDVLKRNRGRRGLDILNRIQKELDIEVEIYEGDFEDIQEVDCKL-----VKL--AKLTC-------GV-VVTNDF--NLNKV-C-E?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????IGRIVALAREEMKRKAEPGMCTKDLDLIGKAVLD-EHGAVCAPEKEYDFPGVTCICVNDEVAHGIPC--TCKILKAGDLVNIDICAEFGGFYCDTGICLCQCAENAFQKGLQQAKAGKRQNQIGRAVYHEARCQGFTVIKTLTGHGIGR-SLHEAPNHIMNGTVIALEPFIC--TKAETIVEAGDG--FKTPDKCMVAQVEHTIVITKDEPIILT--------------------------------------MVEVRN---------VCKQYGGKVVLEETCVT-IQKGKITCFIGPNGAGKCTLLCIMCRLIKKD------------------YI--DGQ-------------------------------------EIGACDCKELAKKMCILKQAN---------------QINIRLTIKDLVC-------------------------------------FGRFP-----------YCQG----RLTEED-----------------------------------------------------------------SYM----------------LCGGQCQRAFIAMVIAQDTDYIFLDEPLNNLDMKHCVEIMKLLKRLVEELGKTIVIVIH--------D
'Caldivirga maquilingensis IC-167'                      GAE-VYLAPCNPLCT-----QDAWKGMNNREYYNAIGFAIC-----SEPDITLDDGGDVAGTLHGGTEETTTGVIRFRAMEKDGKLMYPIIAVNDCYTKYLFDNRYGTGQCTWDGIIRATNLLIAGKVIVVAGYGW-VGRGVAMRAKGLGARRVIVTEPIRALEAVFEGFEVM-PMCEADIFITATGDIRVITLNHMLKMKDGAVLANTGHFNVEIDVEALEKN-AKCKREIRPY-VVE--------YLLPN-GRKIYLIAEGRLVNLCA--AEGHPCEVMDMCFCNQVYRLPQEIDEEIARLKLTAMGVRFDCLTEEQAKYICCWDIGDLEEAKQKIRELVE-LPLKHPELFRHLGIEPPKGVLLIGPPGTGKTLLAKAVANEA-----DAYFVCINGPEIVCKYYGECEARLREIFDEAKRNAP------AIIFIDEIDCIAPKREEVTGEVEKRIVAQLLTLMDGLQERG------QVVVIGATNRPDAVDPALRRPGRFDREINIGMPDKRARLDILGADIAALVKEAAMTRLRGPPGTGKTLLAKA---VANECGANFIAVRGP--EILCKWFDEIDAIAPARGYRI-DCGATDRIVNQILAEMDG--IAPLRNVVVIAATNRPDILDPALLRPGRFDRGIAYIYACCNNTMIIITDLTGCETVARVCGGQVVKADRDKPCPYAAMMAAYKAAQIAMARGINAVHVKVRGPGGY-GLKVPGPGAVAAIRALARAGMIIGRIEDVTPIPHDTIRPPGGRRGRRGPTGRFGARYGMGIRRKVLQIEVKQRGMHRCPQCRCLVRLKRLAFGIWQCPKCGFTFAGGAYIPVDEGAVKPIATGADVMRPGIRELTGCFKPGEIVGKVLKNIHHVDDLRYVADIWKKPYE-DPLRQVIKARLIKWRREPAILRVDKPTRIDKARKYGYKAKQGVVVVRVRVRRGPFNRRRPNTGRRPKRMGVYGVAL-STNLQVVAEQRAARRFCNLEVLGCYWVGEDAMYKWFEVVMIDPCHPAIRNDPDYAWVVGKEYRE---------GRRIRRIIKELVHVTGLNAPAMHVVLE---NGEEMYLPAVEGVYVGKIIGPDAKVEPGNVMPIGKIPEGTMVCNIEKRVGDGGKYARCCGTYGLPCGRMIEVDCRARATIGIVAGGGRIEKPFVKAGNKYHRARTKAWKYPKVRGKAMCAYAHPHGGGCHQQ-GG--TP--VKK-NAPPGQKVGFYGCKRNVGTLAHVDHGKTTTTDCLLMGAGLLCP--KVAGKALALDYVEIEQIRQMTVKAANICLYFEYGGKP----YLINFVDTPGHVDFTGHVTRCLRVMDGALVVVDAVEGVMTQTETVVKQAMEEMVRPVLFINKIDRLIKELRLPPQDIGNRILYITKEFNCLILTMIIEHIPPPDVAQKYRVPKLWKGDLNCPVGKALLDADPNGPLVIAICKINKDPHAG-LIATGRVFCGTIREGDEVYIIGQ-KITKKVLQTYLYMGPNRIIVPEVTAGNIVALMGVDEARAGDTEKMRYVCEPVVTVAIEPKNPNDLAKLVEGLRDLVIEDPTLCLKIDEETGQILLCGVGTLHLEIATW-LLKDRTGLDFVVCQPLVRFRETVRARC-QVFEGK------SPNKHNRLYICVEPGIQHLREIRDYIVQGFRWCMCAGPLAQEPIRGVKVILHDAVVHEDPAHRGPAQIMPATKNAIFACFLCANPTLLEPLLLIDAKTTVDNMGPVTCVITRHRGRVIDVTQTETMEVIVKGEIPVIECFN-ICDELRCATTGRVFWCLQFCRWAPVPDVLCNALMCVKNAECRGDRQVIIWPCCKLIGNVLRVMQRYGYVGEFEYVY-DGK-YVVQLLGR---INDIG-------AIKPRFHVKVDELQK---WEE-KYLP--ARQVGILILTTCKGVVCHLEARENRVGGILVAYVYGDVQLAVIGPPLCGKCALLKCLTPCVC---LGKDCDLNNITLC-IMRNADLT-------GYRIYGALCETILRHLDLIKVYTKEPWACKPTDKPFKY-----ARIGLNYVLND----GDMVCIKDVPQDKLVERIAKYLKDNVPQVKPPQWAIYVKTGRNKDRPPQND-D-WWYFRAAAVLRRVYLNG-PVGLGCLRCCFCYRAK--IGPKARCERTAKAGGAVIRNILHQLEAAGLIERTCA---GRVITPKGRCLMDKLADACNHVAGRLATVVAGKR-VIIINAEKAVVTGDRNMVIDWFKRRMCEIRTHYNPEKVGPKWPRRPDRILRRIIRGMLPY-KRCKGGKVP--PQAMQQLQGAGLNAQEVVNLINNRIKQVAALGFQNLNIEVEYDDCCKRVLRINIDYPPITDIILKVAGKDC------PCHQAGK-EIIGDIPLEKLAEVALIKIEELGCKCFKCALKQVVCTCRCIGLTVNGKDPKEVIKEIDQGKAGMVHVTVVDDRKTCPFFGKELVKAVTVVETPPLYVVGLRA-YAINPLKAELVCVGEGKEVKPTDVFKPGQLVDVIGVTKGKGTQGVIKRFGVKELP-RWHKHRKGCRR-TGTVGP--KPA-VMYTQPRMGQMGFHRRTEYNGFKHYGIVRCGYMLIEGCTPGVVKRLIAFRYPIRGCGIHPREAADHHAFCQGPGLGPALRVGATVARFIAIKYGKPLVPVHHGVAHIEIAKMTT-----GAKDP-LVLLVCGGHTMVTAYCG-GRYRV-FGETMDICVGNCLDMFARFLGLPNP----GVPHLEECAR------RG--KVMLELPYTVKG-----QDMCFAGLYTNTAYYMLAEVTERAGGVARCPILRCIMEIV-ACEYTATLHVVPPEYAGDNGAMIAWTGLLAYKCGRIRIWGTNTDCVDGLARDITGIAKKLGIKVRGPIPLPTRRLMVTVRRAPCGQGYHTYDHWEMRIHKRVVDM-DADERALRQLMRLRI---PEDVKVEIICFNVLCPDLIRKMCVMEVTTCETYDEAGN-PVKGGLMDRRL-GVDEPEARCETCGNDWRRC---PGHFGRIELVRPVVHPEFVK----PIYDILRATCPNCPH-------CREWLEKVPD--DDR----PEWAVLTVLPVPPPQVRPCIQLPCGQTCADDLTHALTTILRYNEKLRNAIECGCPTTCILDLWDCLQANVATYIDNELPGG------IQARHR-SKRPLKGIAQRLKGKEGRFRGCLCGKRVEFCARTVICPDPNLCINEVGVPIDIAKELTVVEPVTEWNIDLMRMLVVNGPETWP-------GANRIERHLMDGDYVLFNRQPCLHKMCMMCHIVKVLPGRTFRLHLAVCPYNADFDGDEMNLHVPQTPEARAEARTIMLV-QNFIVTPRYGGPII--GARQDYICGGYLLCGKQIICTLLPDGYYKGALEAEPGKTIEETLEDKLCEVYIMAKTGARGCLLNAAQMTAALGQQTIR--------GERYRRGRTLPHFLPGDK-GPEARGFVKCNFRDGLCPIEYFFHAGGGRDGLVETAVRTCQCGYAQRRLINAMQDMAQ--IYYVYRVTPCREDVDYEKLE-EIGFGIKALKIHIVTPECDEYTCDEIENILCQIEDIVKGPLGCVAKEFKGL-PVLVCLRDGK----VTVAGHIRNMIIGVTKGWRYKLKVVYAHFPICVKVQGNC--VVIENFLGRRCKIILQI--PQGVKVQV---AK-DD-IVVEGIDKELVCQFAANIGIDEAGRGPVIGPMVIAIVDCKQLTPCGRCRLYKLIDECIPLVCAACIVAKVIRDTIICRLKE---TYGGRLRRPLLIIC---NGGIVEYLDADEGAVAHIIPYCEHNQCPRNIYEAAMAKQGFPYCN-YRYRIDCRGHLLLY-PERPVTTRGLELIG--YCMRPC--------GQNAVLAFMGYCIEDAVMINKAAIERGMFRCIFYRCYETEAMRYPMGD-RITIP--PPTVR--DYRGAEAYAHLDE-DGIVPPEVFVRFY--SALAEC--QL--AGEWKDNCRRGEKGIVDQVLIKVKVRELRGDKFACRHGQKGVVGMIVPMEDMPFTENPHALPCRMGQLLEAIAG-------KGRETMYCGLMGTRLDADIFIGVVYYQKLHHMVADKIHARATGPMQILTRQPTEGRCREGGLRLGEMERDVLIAHGAAALLHERMVECCDKYVMYVCED--CGYAFKLLLQELICLGIYPKLDDGLFVDCLNGFPGPYGIVKGRLCEEPRGCC-GFGYDPVF-IP-------EGYD-LTFAEMGEDLKKTAVARAVIRPGCGVVKVNTIWPM-EVARLKMMEPDIDVTVCGGGFMGQACAVRMAIARLLNLYMLYDCTMIKGDERRTEPKK--PGLKHARCKRQKAYRTRNLTPGKRVYGERVWNPYRCKLLYLGAACGTTVCHVCDIVGLNGLIYGVEFCPRVAQPFQAKILADNGYII--LVIKA-----MCIDVTKEPCETFKR-EIDTIVFYNPAMANN--RCDIDDAAVNLACRNDVDPYGCPAPFINCALLC-IKHGGLLCATATDLAVLQGCYVNKAIRRYGFRPL-RGFLCREIGLRGLLGFIARQALVIDAGVK--PLLAYWERHYYRVCLIVCKDRGTARETAG-NLGLCGPPGTGKTTMVHALALRRICNAE-------KVKCEEDALRLIAECCMGDMRCAINDLDPGLRRYMCLKPMLLPHTEGKYQNRKFGKAMIPIIERMMNQLMGKKQKAYKILKTAFDIIYVATGKNPVQVFVDAVVNVAPREEITRVIYGGIAYPVCVDVGPTRRLDLAIRWIAEGARACC-FNNPRPIEECLANEIIAAANND-PA-SYALRRRDEMERVAATARRG-WRTHCWGRVGQHRCRGQRGGGGKIGL---LKHKKC-LLLKITNG-ELYPLIG--KHGFKLLGEGKIQKPVVVKVRAACAKAIKAIKEAGGGFTFDELM------KMPMNEFIKLLPARQRRTLKR----GVRTHCRDMIILPEMVGLTIFVYNGITYIPVPICPWHIGHYLGEFAITTKIVQHGEPGLKATKCTLHIAAKADNCGAKVVKVIGVVGHYCKNVHRRIPGVCVGDMVVVCVQEGKPE---MRKQILRAIVVRQRRPFRRPDGTWVAFEDNAVVIVTEE-GQ-VKGTEVHGPVAMEAAQR-WPQVACIAETVARLLNVPKCRIVI--KQEALEQLEEAITRNDVRCLMKEGLIEVKPRKRNCRGRWRITHEKRK-SGRRRGRGCRRGTRKARGAVGKEVWVPRIRRIRRFLNTLKHRGV-IDKATWRNLYRMAKGGYFECLAHLWKPRTEIGRLVKEGKIKCIDDIFIANARIQEPEIVDALL-TNLGEVCQFQVAVALGNEDGYVGIGVGKARQIGPAMEKAIREAKVNIIPVRRGCGCWYCCCDEPHCVPFVVRGRCGCVFVELIPAPKGVGLVAGDTIKPILRLAGIKDVWCRALG-----ETRTTLNFAMATWNALEYLNIALTRNRYVDCIIQRT-TLGTRIVIIAEKKNRIIGRKGQQVKALADILKCKFN-LDNVVIDVIQE---PHPEYNARLVALRIADAMAKGIR-FRRAAIIALRQLQEA-NVQGAEVIICGKLTT-ERCRFEKYTTGIVIKAGQDALEKVQEAVIPVLLKPGIFCVRVRVLPP--DAKLCDIRVILTPEARCRLDNLRLIKPELVECIENQLIALAQCGRIKVPITDEELKKILHCGTLDPGVCGVLPIALGDCTKVLQGICNVDKEYFTGKIYQRPPLKCAVRRIRVKTVYCLDI--MGTYIRKLCYDIGEVLGVGACMRELRRTRVGCFREENT--VNLPVEEMVIHLPRIYIRDCAVDAIAHGACLAAPGVALMTLKGELVPTVPRPNRPVTLGCRL-IWTFLAATVYLLLCVTPLYGG--TLAQLGIGPIIIAGIIMELVAFC--ELMDVDLND-PKDQARFTALTKQMLF-GAVIVILLDDLICKG-----IGCGICLFILICITIVLGGFIAYVELMEVRIPPFKVMYVCVLPIIFAYL--WVNLAGLCA-EDQARTMVCCGLCIPGFRACARCLAVHLKRYVNCLTFTCGLLAGFIAALGDVL---GVYG-------TGIGLILMVEIIIQYYTIAMQEQLFEAYPLVKYGVVKFGD---FTLCCGVKCYVDMRMAICIPG--T--LYVRKADKGTRRR--IEG-YYK--GGEGVLLIDDVVTTGGTILDCIRVLEENGGLYAARKLRRKRQKFRWCDIQYKKRAL-GFIKKYDPLEGA------PMARGIVLEKVGVEARKPNAAVRKVRVQLTKNGKVVTAFVPWDGGLNLINEHDEVIIERIGGPEG-RAYGDLPGVRFKVTK--VNGVCLKAILLGK----KQKPVRLVPVERYM-----AAAVRLGARVC--NNYLQERGFIFCVRP-DGLRIFNLKRIDERIRIAARMITRY--PPCRVMVHCTKPYAFKPIQMFCKFVGCLPVTGRLIPGTLTNPYLTHHID--------IDLLMVADPKTDFQAINEACLTGIPVIALVDTDCDPTFIDLMIPCNNKGRNCLALVFWLLAR-QV---LRERKQCIVVRGDLRMCRGKLAVQVAHAWVCGGQKKIVLVVDCVEDLIRLKAKAECLGLPTALIEDAGLTELPPGTVTALAIGPGPEELVNKVTGCLKLAFIFITGGVMCCVGKGIATACIAKILQARGLCVTAIKVDPYLNVDAGTMNPYQHGEVYVTAD--------G-----GETDLDLGHYERFLDVELCKCHNITCGQVYLCVIDGERRGVYLGQTVQLIPHVTNEIKARIDAVVIEIGGTVGDYECLPFLEAARQMRLEEN-GNVVFVHVAPVPILDVTDEFKTKPLQHCVMELRRVGIQPDIIIIRCTRPITNDVKAKVCLFTNVPQNLIFNCFNVDTIYRVPLILDEQGLRDAYICIVEAIRHDAYIILPGFGARGVEGKIMAIRYARENNIPLLGICYGMQLCVVEYARDVLGLKDAHTTEVNPNTTHPVEKCI----NKLGGTMILGDREICITEGCILHGIY-GCLRIRERHRHRYEVNPA-YFKQLQEAG-----LVFC----AMR-IDVPRVEAIEL--HN--HYFFIATQFHPEFRCRLTRPHPLFRRFNQCVDLIIKLRDVDVKK-PENRICVTVPLPNPLC-KQTKVCVIACGATITAARDAGADLVITRDDLGKYC-DKKCVRKLAQQYDFFLATPDLMVQIGRTM-GPILGPRGKMPVRVRLRDQPQIMVKVGTEDMDPCKIAENALAVLEEVARKY--GWD--KIKEVELKLTMCMGDPKRP-KKKYVEGKPKRLWNCDLLMCELRLIGEYGLR---NKKELWLARALLRCI-KH--RAREILFRMGLI--SDINIPLDCVLALDVTAVLERRLQTLVYRKGMARCIHEARQLIVHGHICINGVRVRCPGYLVPRNLEDGIITRFVLTEKAIRLAEKENTLTIVVPRCVNKKVIKDYVEKAYKVKVIDVRTKKAYVRLCCEN--NAIELLTNLGLLNLNGEAVGEVDL-PEHFKTPIRLDLIRRAVLCALTARLQPKGTDKEAGLRTCA------VCFGT--GLGIARVP-R--IKGNMWP---R-ARIAPNVVKGRRAHPPKVEKRLWERINRKERLLAIRCAIAATAVRELIMARGHLVGDVKAI--PLVVVNEFEG-ICKAADVKNVFKALGVWCDVVKAQGNV-RIRAGRGKMRGRRYKEPKCILVVNMAGVDVVYVDNLCILHLAPGGVPGRLTLWTQGAVKYDAKGEHFEIIVDPEYALEFK--LGK-P-ICLDKVLITDTVFRDCKRGLRACEIALKRVFGTTDHRKAAEIILRNAEIPLTCEQRRRLIEDKKKQIIDWICRNCIDAR-TKAPLPPQRIELALNNVDVAIDPFKGVDEQINDVLKALQKVIPIKVAVATLEVTVGPEHGQRVKCALARMG--RILKEQYDECGNLILQL-EVPAGLQDTVIGKVNEMTHGVCKIKDGIVIDHIPAGRA--------LIVLRVLKLK--GGEGR--VALVMNADCRRLG-R-KDIVKIEGKELCNDELNLVCLIAPTATINIIRDYCVIKKFQVKLPETVKGV--VKCRNPKCITNQPR-EDAVPTFRVL-HLD-QPILQCQYCTNQYLRMTVRFLEKAHRQYNAALWATVADILCKPRRCRV--TVNVGKLNRLLNDG-----DVVVVPGKVLGDGELCKK-VTVAAWAFCKTAIDKIKAAGGEA--LCIPELVR--RMPKPCGVKIPIRCWTCGRPLGHLWEPFRNRV--LAGE---DP-----GKVLDDLHVTRYCCRRTLLAHIKEGCYIMI------DNMPCRVVEVEKCKTGKHGCAKARIVGIGVIDGVKRTIVVPTDAAVEVPVIEKFTAQVQLMDLRNYQTGVQVEVWDV-AGYKKIKYLIELGFEVQGTVDI-----IGAFCQTEGLLGCDL----DLRELQNTCRIGRIA---AMLETVDR--------VGPYNAKFQVNCIKDLRCEKRKLIIDRAVECCDTVIIVEGRAD------VVNLIK--HGYRNVIAGACGGIPKTVIELCRRKTT--IAFTDGD--------RGGEM------ILRELLKV-ADID---YIARAPPGK-EVEQLTAKE----IAKALDAAVGK--GIKMLIMTRIG-NI-AKVPMRRIFIWCVAVNMGIGQC---GERLEKAAKVMCELT-GRTPCYRLAHKCIKDFGIRRGEPIGLLVTLRRNEAVWFL-LRALA--AV---DFT-LREECFNA-GNVCFGIREHILVPGCRYDPALGIFGRIVAVFPPEITAVRP-LVKKRVEEYILIGGAPGAGKTTFAQALAEFFVCK-NK-VVKTIECPRDMVLPD---QVTQLCKNLA------TPEELHDIL--------LLCRPDYTIFDEMRDTADIQLYVDLRLAGI-GMVGVIHATCPIDCIQRFIGRVELGMLPCI---VDTVIFIDKGLVCKVYCLEMTVKIPAGLKE--EDLAR-------PV-VVVKDF--ITEEPEY-EGNDCKKVTGGFRAKPYRV-KRKALGGGPPTNTRLC--NRE-KRLIERVTGGNVKIRLCEAGYANVFDKCNGTCKVVKILRIIECPANCDFVKKGIIVKGTIIETELGRAVVTCRPGQDGVINAVKAGDIIHKVLKHTIDKVHPGMCILELCNMIEGEIR-DCGALPA------FP--ANIDVNNVAAHYTAKIGDEAVIPPNCVVKIDVGAHIDGYIVDCAVTLTKAAWTALRNALDTAKAGVELCRIGAIVDKTICCFGFKPIRNLTGHLICRYRLHAGKC-VPNGEVYAIEPFAT--NGRGIVTDAPEVTILMECGNGFVAQFEDTVIVTQDGVEPLACQ-PRKCC-QECIRFCPITD-LCTA--CGICVRKCPFEAITIINLPCELDEH-CVHQYGPCGFKLFKLPM-LKQGKVIGVIGQNALGKTTIANILAGCIIPNKTQ-----YIEL---IPMVI--KGK-VKEALMRINGD---ECKVLEVAGKLNLTHLLNRDINVLCGGELQRLAIAAAILRGGDVYIFDEPTTHLDITERLRVAKAICELTC-G---NRYVLIIDHDLAVLDYLADLVVILYGKP--GAYGIVCCIKGAKEGINEYLKG----YLACENMLIRFKLIARCGQ-LMRGEVVGVLGPNGIGKTTFARILVG--ELQPDE------GY-------KPQYIRDIAVKYPELTVCCIILCGGELQRVMIAAALLKDAELYVLDEPMAYLDIEQRIKTARVIARLAEEKEATVLFIEH--------D
Candidatus_Korarchaeum                                  GAR-IFLCPCNPLCT-----QDAWRGMCECEYFWAIEECLK-----ADPDFTMDDGGDLTVMAHGGTEETTTGVLRLMALERDGKLRYPVIAVNNAETKRNFDNVYGTGQCTIDGILRATNIMIAGKWFVVAGYGY-VGRGIANRARGMGAK-VIVTEPIRALMAAMDGFIVM-PMREADIFVTATGNCGVIKAEHVCCMKDGAILANAGHFDVEVCVKDLELM-SLAKRDLREN-LRE--------YLLPN-GKRVYLLAEGRLVNLVA--AEGHPCEVMDMCFANQVIPVPRWIDCEVARIKLRCMGIEIDCLTKEQEEYLRCWDIGGLKDAIQKIREMVE-LPLRHPELFRHLGIDPPKGVLLYGPPGTGKTLLAKAVANEC-----NAHFICICGPEIMCKYYGECEKRLREIFEEAEKNAP------SIIFMDEIDAIAPKREEVTGEVERRVVAQLLALMDGLKGRG------EVIVIGATNRPEAIDPALRRPGRFDREIEIGVPDREGRKEILGADLAALVREAAMRALRGPPGTGKTLLAKA---VANECEANFICVKGP--EIMCKWVDEIDCIAPIRGYC-SDCGVTERVICQLLTEMDG--LEELRKVVVIAATNRPDLIDPALLRPGRFDRGVAHIYCCFNDTIVHITDITGAETLARYCGGMFVDADRLEGCPYAALKAAMAAAKEAQRKGITHLIVKVRAPGGI-KCRIPGPGATAAIRGLCRCQLTLIRVEDVTPIPHDGCRRPHGRRGRRRCKLR-TTRYGCKIRKRVEFILQKCKRTYKCPYCGA-QAVRRLRLGVWCCKKCGKVFTGGAWEPVDLGAVKPIACGADVMGPGIKDVEGKFNPGDIVGKTIKNIHHAGDRYMEKLVWRKRKEDPELIKLWRERLICWRREPAVVRVERPTRPDRARCLGYRAKQGFVVVRVRVRKGGRRKARPRCGRKPAGLGILKLTP-KKCIRWIAEERAARKFPNLEVLNCYYVAEDGKYYWYEVIMVDPHHPVICCDPRINWILNPANKRRVFRGLTCAGKKARGLIKEILHEPGRHTPICLVELE---NGQEFYYIPPEGVYEGQEIGKGAEVKTGNVLPLCEIPDGCLVCNVEIRPGDGGKIARRCGTYALPCRKEKLVDARCRATIGVVAGCGRIEKPFMKAGIKYYHERTHPKRWPVVRGVAMNPVCHPHGGGCHKR-PG--KPTTVAR-TAPPGQKVGHIAARRNIGIIAHVDHGKTTLCDNLLCAAGMICD--KMAGEMRALDYHEIEQQRGITIKAANICLYYQRDGKE----FAINLVDTPGHIDFTGHVTRCLRVIDGAIVVVDCVEEVMVQTETVTRQALEERVRPLLFINKIDRLIKELKLTPQEIQQKILRIIRDFNGLILDMVALHVPDPIEAQCYRVERLWRDKQDEELFNALKNCDPNGPLIMGVNAVRIDPHAG-IVVTGRVFCGTLREGEDVYLINA-KKKQKIQQTCIYMGPYRMRMDEIPAGNIAAVLGLTCACCGETEAIRYVTEPVVTVCVEAKNPQDLPKLIDTLRKLTLQDPNLVMIHNQETGEILLKGTGELHLEICLY-EV-RKAGLEFDVCEPTVVYRECVRGTC-DVVLAK------SPNKLNRIWVTACPGVQRLDEVREILRQGFMWVMKEGPLAGEPVMGVAIRLVNAMIHEDPAHRGPAQLTPAVRKAIFGAMLCANPVLLEPIYEIQVCTPPELIGCVICLICQKRGKVVGIEERGRI-SIVKGFIPVRETLGGFCNEMRCMTCGRAFWQTKFCHWEPLPDPLADAMCTLTNGCMLGKREVVINIACKLIGKVLKVLKEHGYIDEFEYVD-DGK-YVVRLNGR---INKAG-------VIKPRFPVKVGEFCR---WEK-IYLP--AENVGLIIVCTNQGVMTHREAKERGIGGVLIAYCYGAAQLVLIGFTNCGRCTLLATLTPPLI---LEAQGGPTNLAVA-LAKNCDLL-------QFGIDRALGEMILKELGLIRVFTKCKNEKCPCDKAFKY-----AKVGPDFLLED----GDMPTAREVRADLLIERLKEELK-KFDGIKPPDWAYYTKTGCHKERPPIQE-D-WWYIRAACLLRTLYLRGEPVGVERLRTKYGGRKK--RG--VRPERFAKGCGHVIRLILQQLECLGLVEKVEG--RGRRICPAGICLLDKLADAENKILGRIACLAAGKR-VAIVNAEKAIICGNPETILKKYQ-TRRCIQCRINP-RKCPVQPRTPDRIVWRTVRGMLPM-KKAKGGKATPGPPLGPALGGLGLNMGQIVKEINEKTCCYC--GMRVP-VEIEV-DTETKKFEIRVGTPPTCMLILRELKAEK------GCCDACK-KI-GNLKMETVVNIAKMKLACCNTPELKQVVKQVLGTALCMGVTVEGKDPREVQREVDCGKVGMVHVLLKEDRPGKLNLGQQITLACTVIETPPIEIVGFRA-YKEGYYG--LKPLTTGCQLKVDCVFKVGQLVDVTAVTKGHGWQGVVRRFGIELLR---HKAGKGRWR-VGCLGC-RHPPYVTWRVPRAGQTGYHKRTEYNGFKNYGILRCQYILLCGCVPGPAKRFVFIRHPIRG-GMRPHDIAEHHGFCRGPGIGQALTVGAFIARCLCLKIERPLFGVNHPIAHIEIGRAVT-----GCRDP-VILYVCGGNTQVICHNG-RRYVV-LGETLDIGLGNAQDRLGREVGLPFP----PGPIMDKI--------EG---NWVELPYTVKG-----MDLCFCGLLTEVAFCMTVEVAERAGGVAACPRFREKVRKM-CEERGAKLKVPPPDLARDNGAMIAWTAFLCYKYNRIELVCVNPECLEKVCRMFKEIADKMGVRVKGPIPLPTKRLRVTALRNPCGEGTNRYDKYELRIHKRIIDIPNPDERYIRCIMGITL---PDDVKICIVIFGLICPADARKIGFIEITEPTAYDEGGL-PVQGGVLDPRL-GTINPRQRCPVCGNLPKNC---PGHFGRIELAMPVIHIGYVK----RIKDVLNTVCHKCPH-------CRDILEKICD--DDR----PEWAVLTVLLVPPLTARPCIYLETGERCEDDLTHILVEILKANRKLNNCKKVGAPVCMVECEWDHLQYWVCVFFNNATAGM------PVAMQKGTRRPLKCLFQRLCGKEGRLRKNLIGKRVNFCARTVICPDPMIDIDEVGVPVEIAMVLTVPEYVNENNIEKMKELVMRGPDEYP-------GANAVERHLMDGDYVIFNRQPCLHKLCMLGHRVKVLPGATFRLHPAVCPYNADFDGDEMNLHVPQILDGCVEVRELMGV-KYNMLCPRTGGCII--GARQDFITALYMITGKQLICMLLPNGYRTKE-ELLRIMREEQMLEFDICNVCIMAKTGARGCMANLAQIVGQVGQQKVKTRIGFVLTCGRPRKGRVLCYFQRGDL-SPEARGFVKNCYVCGLNPAEFIFHAMCCRECLIDKGRRTEDCGYFYRRVANCLKDMAR--ILAIYRVLLDG-SICCDEAN-PIGFGIVALNLKITAPEED-GITDAICCVLEELEGVVCGPKGTLEREFHCE-LIELCIEGGK----VTVTAHIRNMMKGVTEGFRKEMVVVYAHFPIKVEVDKGRKIVKICNFLGEKLPRYACIV-G-DTEVRV---EG-DR-IYIEGICKEDVGQTAANIGIDEAGRGPVIGPMVVAAVDCKLLCAERREELFPMIDCKYIQVACACIIAKVERDRRIRELCE---LTGGRMRRPLIPVC-----GVVELLDADEGVAACQIPYAEHNNIPRDIIGCNMVRQGEYLAN-WRLRFDCRAFLMFY-PQRPVETRGAEITG--YNYRPC--------GQNLVVAMDGYNMDDALVMCKGAIDRGAARAVFFRTYETEARRHAIID-KFENPVALKKVC--GKKEEQYYQKLGE-DGIVDPETYVRFC--PELTVGCGYPQYTFERRDTCRAWERGVVTDVLVRVNVRETRGDKFATRHGQKGVLGMIYRHEDMPFTADPHTIPCRMGQLYEIIAG-------KGEEIMYDGRTGRMIKAPVFIGICYYQRLKHMVRDKIHARARGQMQLLTRQPVEGRARGGGLRLGEMEGEVLICHGAACVIRDRYIDQCDKTIIYVCKE--CGYACKLFIEELMCGHVDVRLDCGLFIEALNGFPGPYGRVQGTIAREVRGG--GWGFDPIF-IP-------NGCN-KTYGELG-DEKKTARAMAVIRKGCGRLYINEVFAPNEFVRMKILEPDIFARVKGGGFMAQADALRMAIGRLKEIFKEYDRTILKGDPRQTEPKK--YGGRCARARFQKCYRTRNLTPGIKVYDERIWNPRRCKLLYLGIACGTTACHICDIIEECGVIFGVEVAHWVAQPDQVDILLKNGVAV--IAVKA-----SCIDVTLPPKKIYKRVEREVLIFYNPRMKLN--RDDCNCLCAQIIKMNDLDPFGCPAPFLDCFLRA-VKRGGIIGITATDEPPLFGIYPDKLLRYYGVWGK-KLPFCKEFGIRCLICFTIRTAARLDLAAE--PLLCYGEGHYVRAYFRIERGAERCKHLLK-ELGIVGPPGTGKTCAAHAIALKDICRKE-------GLCVPEEVLNKIAKCCQGDLRAAINDLNAALKNVICLKPVYLPHTGGRHEHKKFGKLEIPIVERLVNRLMGKKLKAMRTVKYAFEIIELRTGKNPIQVFLDAIENCIIREEVTRIMYGGVCYFHAVDTCPCRMVDLAIRHIAQGAAMKA-FRCPRCLAEALAEEIIAAAEYDRNR-SFAIRRKEEIERIALCCRRG-SRLHGYGLQRQHRRCGRIGGFGMAGT---KKHLWT-WVTAYEPD-----YFGRGRRGFKLLGRGEVCRPLLIKVECACKNAVCKLECMGGGYTLEQLQ------TMTLDELANVMPCRIRRTLKR----GIRTHRRDMPILPEMVGCKIAVHNGKEFVEITIVPEMIGHYLGEFAMTNRIVRHGKPGKGATRCCKFVPLKADNTGAKLLMIIGVHG-Y-KGRKDRVPTACVGDMVTVVVKRGKYD---LMHKPFKAIVVRQRMPYRRKNGQWVVFEDNAAVLVNDD-GT-PRGCEFRGPIAKEAIER-WPCLCVICKLAAKVAGVGLDRVRI--NPEKIDLVCEAVTRADIRRLIRCGAIEILQKRGICGARKK---------PRRKGPGCRKGGKYCKL-PRKRRWIRKIRALRRELRRMKEQGL-IDCKEYRELY--AKLCCFNCVCQLWVPKTWVGRLVAEGKIKCLEEILRRGIPIQEPEIVDILV-PGIGELTQLRVVAAVGDGMNYVGVGKGKGKEFNIALADAVRNAKLNLIKVRKGCGCWECGCGRPHCIAAAVTGACGCVRVTLLPAPRKLGIVGNETAKIVLGLGGLQDVRVFCKG-----HTRNRMNYAFALHDALEFMEKICDKAGFHGVEICCT-PIRDIITVYVECPGVMIGRGGRTCKRICDILKEELG-IQNPYIQAKKV---DKPFLCTRIVACYIARRIAKGER-YKKVAYCALGRVMAE-GAKGVEIRLCGKFGC-QRAREERFREGVIYRCGQDYIENVEYAVKHVLMPQGMIGVRVRIVKP--GVRGPDVKCLLTCDAWQRLKRVELVKPELANDVKIYLIQLYCAGKLTRKLTDDELKTLLHCGTLDPKVCGVLPIVLGNATKLCKFICGYDKEYFTGPIFQRPPVKCAVRCLRVRRVYCIEL--LGTYIRKLFFDIGEFLGVGGCMRDLRRIRCGIFTEKDC--VTLPLEEAVRHLPKIYVKDCAVACLTHGACLKVKGVALMTLKGELIPEVERPKRCPTLKEKL-AWTGLVLIVYYFLTQVPLYGG--SIVELGIGPIVTAGIVLELLVGC--KIVKLDLTD-PEDRKFFQEAQRQLCL-GCFLLMMLDDLVAKG-----IGCGICLFILAGVTFVVFIAVIWAYEVRVNICPIRLLYVCNVPIIFAKI--WVMTAGMDP-RTICEQLVRQGIVVPGRRACAKVVARTIEKYIEAVTYLGGILVGLLAALANFT---GAFG-------TGCGILLAVTIIAGLYERLAQERTLEMYPLICRGMLKFGE---FTLTCGKKCYVDLRPLPCFPP--L--IYVRKEKKGTECL--LEG-SLN---MRCYVIIDDVATTGGCILNAARIVRNYGGLYAARILREKYKEKRLHCWRVKRRLY-RLKEKFDPLEGA------PMARGIVLEKVGLEARQPHCGLRKVKVQLAKNGVIITAFAPGDGALNVINEHDEVVVEGIGGCRG-RCMGDIPGVRFKVIK--VNGVCLEAILRGK----KEKPCRLIPRQKYL-----LCGVHVGTGIR--TKDMEK--FIYRVRP-DGLCIIDIRKIDERIRTAGKFLARF--DPDRVLAVCARIYGFKPVRKFAEYTGAMYITGRILPGTLTNPQAPLHLE--------PDVVLLCDPRVDRQIHIECVRMGIPVVALVDADNMLENIDLAIPVNNKGRRCLALVYWLLTR-EV---LRNRKQVIVVRKDLGMCCGKIAVQVAHAWKEEGAKKVVLEVRCEEELIEIHKEALDRGLVCVLIRDAGLTELEPGTATAVGIGPHEEEKIDRITGKLPLKLILVTGGVICGLGKGVVAACIGKIVQCRGLCVCMIKIDPYLNPDPGTLNPVEHGEVFITEDVWNFCPG-GVEFKIAEIDEDFGHYERFLDINMHPCNNITCGQVMLCVILGERRGHYLGQTIRLIPHVTNEIKCRIDVLIVELGGTVGDYEAMAFVEALRQLRLELGCGNCLHVHVTYVPFVETVGEFKTKPAQLFFREILAAGLPPDIVIARTCCPLPENVKKKLALYACVPLNCVFDDPNLCVTYELPLYLENQGMADVYICILEAIKHDGIVLTPGFGCRGTEGMIYAACWALKNEKPFLGICFGAQLATVAFAREVMGWKGANCTEIDANTPWPVQKAV----KEIGGTMRLGGHEVVLLGGKL-RAAY-GRDRIVERFRHRYHIIKE-YAERMEGAG-----YRVT----AVD-PCGEIINAFEV--EG--HPYFVGVQFHPEFKCRPGRPCPTYRRFNEAVDLVVVLRGIDLKRDPNAKINEVVELPHCPRNRKTKVAVIGKGEFLCKAKEAGADRVLEPEEIEAIAANKRALKKLANEYDFFIAQADVLPKIVKYI-GPVLGPRNKMPVRIRTKDQPIIHTKVGCRDMKPEEIVENIRAVLCAIERKYEDPC---KICRVYVKTTMGMGDIRKH-RKKYER--PYKPWDRRVLEETNRLAGYYGLR---NKRELWRMCFLAKKY-RR--IARQLLQALGIL---SKDATLDDLLDLCVEQFLERRLQTIVWRKGFAKCPYMARQLITHGHIRVNGRRIRQPCYLVKIEEEDKILKAPICTEKAVRMINEENKLAFYVDIKACKCEIKRAVEEAFDVKVVCVRTKKAYVKLCPEF--KACDIACKLGVYNLNGEVIGRIEL-PPLFELDVRQDIIRRVYLCQLTARIQPQGRDPLAGLRTCA------ECLGV--GHGIARVP-R--VKGRGYPAAGR-AARAVMAVGGAKTKAPRCWKVVWERVNKKERRLAIGCAIAATCHPELVGAR-HRIPEGIAL--PIVVCDDIEC-IAKTCDLHKLLKKLGLEEELERCKRRFGKIRAGRGKMRGRVRQRARGPLIINIPGVDAVCLRNLCVMHLAPGGKPGRLTIWCECCARITRAGKRFEIFVYPDKAYQFK--EGK-Q-VDIKCILAVECVFTDARKCEVAPCCELKKAFGTTDLYCIAETILREGEVQLTAEYRKKLQEEKIRWIINYIHKNFVDPQ-TNLPHPVARIEKAMKEAKVRIDPMKDPEQQIKDVVEQLRKILPLKTGLVKMVVTVPCCAWAKARCLLLGQG--NIICEKWCDDGEKVTLVAEVPVGCQMLLFERIGEMG-GVRRICDGTVIDHIPAGRA--------LRVLKLLGITGERDGV---VALVMNVPCKKLG-K-KDIVKIEGRELCKEEVDKICLIAPCATINIIRNFEVACKRRVELPRRVVGI--LRCLNPNCVTNAPR-EAVEPCFTLI-SEC-PLRMVCEYCTNIRLVRMIRNLEIACRVNDAPIWKAVAEKLRRQTRRRI--EVNLWKIEKYCDGV-----AAVVVPGKVLGEGEITKP-VIVAAAGFTRCAKRKIEEAGGKA--ILLDDYAK--INPKGCHTRIPIRCFTCGCVIGDKWEEFCRRV--MAGE---DP-----GEVLDCMNIKRYCCRRMFLCHLRKGCYVIL------DDEPCEVLEVCKCKPGKHGCAKVRVEARGIFDGARRCKIFPADALVEIPIVDKKTAQVQLMDLETYETGIEVEYWEC-MGKRKIKYIAKLEVCVNGAVDV-----IGAFGQLEGLLGPEL----ELKDLQRTGKIGRIV---AAMETIDK--------VGPYQANFKLIKIVDEREERRNDIARRAIEEACEIIVVEGRAD------VMNLLK--YGFDNVIAGALERVPKCLEKLIEEKEA--IAFVDGD--------RGGEM------VLRTLLEQ-TDID---YVARAPEGK-VVEELTAKE----IRKALDKAYEI--GVKAIVGNVAK-DI-VRKGMLIPRVMAVTLNIAVGRC---GEVLTRAGKVLEELT-GQKPVERRAKRTIREFGIRKKEPIAVCVTVRGKKAVELL-DRVAE--AV---GRR-VKACCFDELGNFAFGIKEHIDIPGVKYKAEIGIFGRVLAAFPPEITAVRP-LVKVTLDDYILIAGPPGAGKTTFACALAEFYKER-GR-IVKTLECPRDLQVGP---EITQYGRLAG------SFENTADLL--------LLVRPDYVIFDEMRKTQDFKIFVDMRLAGV-GMVGVVHCGFPIEAIQRFIDRVDLGVLPHV---VDTVIFIKDGKVEKVYCLKITVKMPTGMKD--VALAR-------PV-VLVKDF--ETETVEY-EGG--RKPTGG-KIRVCRG-KRKREAGRHPAFTTIG--ER--RLKLVRIRGGGVKLRLICGNEVNVAV-GGGVTKRAKILGFIENPCDKTLCRRGIITRGALVRTELGVVRITCRAGQHGLLNGVLLGEVHCCILENFVCRVREGARLIDIAEECERRIR-EMGYEPA------FP--TNICVNQIAAHYTPFPGDDGCIPPCCLVKLDMGAHDKGIIVDAARTMAEVAREALLKAIERMAPGRKLIEVCEAIYETIVCCGYKPICNLTGHKIEIYRLHAGID-VPNWDVFAIEPFVTTPDCKGYVVCQGEPLILIEVCGRPVAQYEDTILVTPEGAINLTCN-PKKCG-LECIKYCPIDEKLCTG--CGICVKKCPFGAICVVNLPAPVEGE-EVHRYGVNGFTLFRLPI-VRPCKVLGLVGPNGVGKTTCICILCGRIKPNKPE-----RIDK---IPEVV--RGR-VCDVLRRVDER---G-SYDEVNCILELENIRDRDLRELCGGELQKVAIAAAYLREGDLYIFDEPTNYLDVFQRMKAAKLLRELQN-K---NKCLIVVEHDLAILDYLCDYVHILYGEP--GVYGVVCHPHPTREGINIFLDG----YLPDDNVRFRFCLHVCGAQ-IYVGEVVVAVGPNGIGKTTFIRLLAG--ELQPDE------GY-------KPQYV-RPC---YDGTVECLLLCGGELQKVAIAACLGREADIYLIDEPCAFLDVEARFCVAKAIRRRIKGERKAVIVVEH--------D
Cenarchaeum_symbiosum                                   GAR-VAACCGNPLTT-----QDAWAGQNPKEYDWCIDQVLC-----HGPCVITDDGADMNVKAHGCTEETTAGINRIRAMEKQGRLRYPVIAVNDADTKHMFDNRYGTGQCTIDGYLRCMNLLLACKRVVVAGYGW-VGKGVAARCRGMGCR-VMVTEPVRALEAHMEGYEVV-PMCRADIFITCTGMTGIIRKEHIDKMKDGAVMGNVGHFDVEIDTKYLLKK-SRCVREIRPN-LDE--------CVLKN-GRRVYLVGKGWLANLVA--AEGHPPEVMAQCFCNQLIPVPVEIDQCIARDALAAMGIRIDRLNAEQAKYGDCWDIGGLTDEIKKVREMIE-LPLRHPEIFEKLGIEAPKGVLLYGPPGTGKTLLAKAVANEC-----NAHFICICGPEIMCKFYGECEARLREIFKEAREKAP------SIIFVDEIDCIAPKREEVTGEVERRVVCQMLCLMDGLEARG------KVIVICATNRPNAIDPALRRPGRFDREIEIKVPDKKGRKDILGADLEYLCKEAAMKCLRGACGTGKTLLAKA---VATQCEANFVCVKGP--ELLCKWVDEVDCIAPVRGADCAATNITERVVCQLLTELDG--MENLHGVVVLAATNRADMIDPALLRPGRFDK---------------MTDLTGAETVCICCGGVHVNADRYECCPFAAMKAANKVIECARAKGFTGFHIRVRAVGGV-GCRVPGPGAQAAIRALARGGFRIGRIDDVTPIPHDTTRKKGGKRGRRCLKG-LGARYGIKIRKEYTKIHFQLKEKRPCPECGC-AKFGRVAVGIWECRKCGFKVAGTAYGVVDMGAVCFMCKGANVMRPGITGF-AEFGLGDIVGEIVKNLHYICDLICRDRLWVKLWR-SNCHDI-RDRVIIWRKQNAVTRIERPTRIDRARCLGYKAKQGIVVVRMRVGTGGMRRQRPRGGRRPKHLGVTRIKA-DVCMKQVAVRRVLERYPNMCLLGCYFVYKDGAYYWFEVILADPCHPRVAKDPEL--------RDR--VGARAA-------VIDLVHERGRDAPLAKIRFE---DGIVCYVPAVLGTRVGCCMGLKCEIRDGNVICVQNIPDGTTVCNVEKHYGDGGAIVKCAGGNALPCGRFCTLNPKNRAMVGTLAGGGVCERPFMCAGGKWRRFRCKGRKYPIVRGVAQAAYVHPHGGGRHQH-VG--QCCTVCR-NAPPGAKVGCIAARRNFGVIAHVDHGKTTMCDCLLAHCGIIAP--SAAGQALAMDFDKEEQERGITIYQANVTLHYTQKEDE----YVINMIDTPGHVDFCGRVIRCLRAIDGAVVVCDAVEGIMTQTETVTRMALEELVRPVLFINKVDRLIKELRLTPEKMQETLACVVCNFNQLLLGMVVKHHPPPHVAQKYRIPKIWHGDLECDIGKALLACKDDGPTIMMVVNMVLDKAAG-SVAIGRLFCGTIRDGQTVNIIDA-KREGRVQCVNFFMGNQREQVGELGAGNIPALIGLADCRAGNTEGVCYVCEPVVQIAVEPKHPKDLPRLVEVLKQLTIEDPNLVVKIDEECGETIVCGMGVLHLDVATH-RI-QDAKVEIITCEPLINYRETVCCGC-EAVMCK------SPNRHNKIFMRVEPGVQFVQECTDCINCGFDDAMKEGPMCREQMRDCKFTFTHFVPHEDAAHRGLCQLGPACRRACMGALLTAGTCLLEPILAIEVRVPTDMVGNVATVLCCKCGKVMDMIQKGPA-SIVTGEIPACETFT-LCEEMRGQTAGKAMWNCHFKRWAEVPNILANLFVTLYNTEARRRGDCQVYPTCKLGVEVLGTLKKAGYIGEFEHVE-DGK-FCVHLLAK---ITKCG-------AICPRFKVKKGEYTF---WEQ-QYLP--SYDRGMLVVTTNQGVMCHHEAAERGIGGFLIGYVYGDATVVFIGMPCVGKCTLLNRLTPGII-KGACGGKGLGKRILC-VARCADLH-------LYGYTCALKERIYQELAFIRIYMRPKGGPTDYEEPFRY-----ALVGICHTLYD----ED------VPADVLIGRLAEILKKE--ELPRPDWVPFVKTGVHADKPPQDR-A-WWHTRCACLMRKIYLHG-PIGINGLRCEYGGGKP--RG--YGAANHRKAGGAIIRNAVHGLEKLGYIEKLDK--KGRIVCRQGMQKLDRLCDATDHIAGRLACNVAGNR-VCIINCEKVMICGKRACIVREYR-DFLKIACIIHP-EHGPYHPRRPDTIMTRMIRGMLPR-KKPCGGQACAGPPLGPAMGPLGVNIMEVIAAINDETKDFE--GMKVP-VTVCV-DTDTKKWEVEVGIPCAAALLLKEAGIQK------GCGTPGT-EWVGDVTMDCVAKVARTKLECCYACCVKQVAKVVAGTCVPLGIKIEGKTPREITAEINEGKAGCIQIVCIDDREHTPNAGKQLVCLGTVLVTPPLHVLGMRG-YCKGHYG--RHVKFDGKTVKACDVLEPGAGVDVAAITKGKGWQGVIQRMGAK--R-KQHKCRKTVRE-LGCLGP-ICPQNVMYTVPRAGQMGFHQRIEYNGYKHFGMVKGDYIVLKGCVPGTYRRLVKLRAQIR--------------------------VGAVVARALCCYHGIPIYPVNHAIGHIELGKLLT-----GAQDP-LVLLVCGGHTMLLAFVG-GRWRV-FGETLDITLGQLLDQFGRCLGFPCP----CGRQVEELAA------EC--SEYTDLPYCVKG-----NDVCFCGLLCETAFAMVAEAVERAGGVAANKRLAGMLEGA-CGRQRCRLFVVPPVYCGDCGAQIACTGLLEACIKRVKLTCINLLKLDGVCGIIMDIGKRTGVRIKGPTPLPVKKLHIATRKCPCGCGTETYEKWEMRMHRRIIDI-SADDKTIRRLIDLKI---PDDVHLELIRFCVWCPHEIRKYCVAEITAPETYDEEGM-PVQGGLMDGRL-GTLEPGQKCLTCGNTAARC---PGHFGHIELAEPILHIAFID----NIHKLLLGMCRCCPH-------CREKFCQITN--EDR----PEWFILQALPVPPVTVRPCIILETGIRCEDDLTHKMVDIIRVNQRLKECKEAGTPPLIVQDLVDLLQYHATTYFDNEICGI------PQAHHR-SGRPLKTLTQRLKGKEGRFRGCLCGKRVDFCCRTVICPDPNLDLCEVGVPECVAMKLTIPEIVTEWNIARMKELVVNGPDHYP-------GVNYIERHLLDGDIVMFNRQPCLHQMCIMAHHVRVLPGKTFRLHPCVCPYNADFDGDEMNLHVPQCEEARAEAMLLMRV-QDQLICPRYGGPII--GGLRDFITGCYLLTGKQLFCLFLPNGAKKGGLRLTRGLCPDEALEAYINAGKIMACTGARGCCLNIGQMAGCLGQQCRR--------GQRLLKGRALPHFRENDD-SPDAHGFVKCNYRDGLCALEFFFHAMAGREGLVDTAVRTQQCGYMQRRLINALEHMAQ--LLVIVKILPKGTEVDLDEME-PLAFGLHFVKAEFILEDKE-GQNDALEATVRCAKGVVKGKLGCAHKCFRKI-PVGIRIDGCC----VTARCIVRNLCEGVGVGYTIKLKVVYAHFPITIKQDGAM--ILVENFQGERCARKAKIV-G-GTKVVC---KG-ED-VIVTGHVLTDVCQTAANLGVDEAGRGCLVGPLVIAGVDCKKLTRKARECLYPEIDDRFVIVCAACILAKVARDRCIERLRK---SH-GRVLRPMIIIK---DGGVIELIDANEGAGACIIPYPEHNQCPRNTYECAMAKQGFCTPM-MNTCTYVRQHFMLY-PQTPVNTRAMGLLG--LEDRPA--------GQNCVVAFDGYNIEDAIVLCKCCVDRGLARTFFYRIYDAEAKQYPGGD-NFEIPGAEDNIR--GYKGEKCYRLLED-DGVIACECTVRFM--EEYKEFE-PC--GPYRRDTCRPCETGVVDTVMYKIRVRDMRGDKFAARHGQKGVLGILAKNEDLPYTANPHAFPCRMGMFMECITG-------KGKEIMYDGRTGKAFPVEVFIGVVYYQKLHHMVADKIHARARGQVQMLTKQPTEGRARGGGLRFGEMERDCLIAYGACMILKDRLLDECDKCDIYVCER--CGYAFKLLLQEMQCLNVAPRLDDGLYIDCLGGFPGPYGEVRGEIAGDQRGK--GWGYDPVF-VP-------EGGA-TTFAEM--DGKKAACAHVYIIKGTGRVRINEMIVH-ECAREAILAPDICVRVKGGGFMGQAGACATGICRLRKRIGDFDKYLICGDARRKEPKK--FGGPGARRRKQKCYR---MDPGCCVYGERLWDPFRCKLLYLGACTGTTACHVCDIVGGRGAVFAVEPAGRIAQPDQTAMAVANGCLL--LVIKA-----RCIDCVRDPAGVIRE-ETAKLAFFNPRARAN--RDDTNEQALNIARECDIDPFGCPAPHLDCCLRA-VCHGGMLCITATDLQVLNGIFPDACRRIYGGCPA-RAVFGAEAAVRLLLGCLRNVAARLGVCFE--PLLTECDQHYYRCYVRVLARRDTCE-----NMGLVGPPGTGKTTVANLAALRKVLCEE-------GACLCPGAEIKVICECRGDIRCMLNLADPGLKTAICLRKMTLPYTYGRCALKRFNKADANIVERLANKMMGKKMGCINTVKTAFEIINLKTGRNPVEVLVRAVENCAPNEDTTRIVYGGTVYHVCVDVCPLRRVDLALRFIADGVKEAA-FRKPKCLEEFLAEHLILAANNT-TD-APCVKKKNELERIAQACRRG-SRTHGWGQVGQHRACGHKGGVGVCGQ---LKHHFC-SMLKEDPG-----HFG--HDCTKLLGGGTVCGAYCVKICRLTACAEEKIKRAGGGKPAEELE------SMPLDCLFRLFNCRQRRCLTR----GIKTHLRDLIVLPCMTGVTVNVFCGKEFRPVEITTEMIGHYLGEYVITNKRVCHGAPGVGACRCCLYVPLKADNCGAKVLEIIMVQK-A-KTRVCRLPAAAVGDYVNVVVKKGPAE---LRKQVHGAVIIRQKYPVRRLNGVRVAFEDNAAVLTTPE-GE-MKGTDIKGPVAAEACEK-WPRLANLARLACRVTGAGIHRIYF--DPTHLDDIADAITRNDIRCLITANTIKIKPVCGTCRGRAQHKRRQKAKRGCKA--GCKQGRMGARV-GKKQVYVKKVRALRYLLAVFKDRKD-ITNPEFWALYKKVGGNTVRNKAHLWVPKTALGKRVNAGEITCLEEIQEAGARIQECGIIKKLL-PDLGQCTRFKAIVAAGNENGYLGIGQGKAKQMRIAIEKANNQALLNVGPIKLGCGCWECRCDQKHCVPFKVRGKGGCVVIEILPAPRGLGLVAGGKIRRLLELAGLKDAYTTAKG-----STPTTNCTCKAVLECLEFLRENIKDCGFCGVEVEKN-PRGTKITLHVTRPGIVIGRKGVGIRELTERLEKDFD-LKCPQVDVKEI---ETPELYPGVMCNRMACHIERGTA-FRRATMWTIQQIMEKKDAMGVQITICGKLRG-DRCAFEKHTCGILPRAGHYADVIVLDDVVHVKTPMGLIGIRIRIARR--D-KFRKLKQILEPQARMRLCNIRMVKPETAAALECHLINAACQGRLAGKICDEHLKQILHCGTLDPQVCGVLPLGLGEATKALGVLLIGPKEYFTGPIHQKPPQRCCVRRTRVKTIHEIEV--LGTYIRKLLYDMGEVVGCGACMIELRRTRVDHFTEGCGL-VTMPVEEALAGIKAVVIRDCAVDALCHGAQLAIPGAGVYTQKGEVVPQVPKPKKKLCLQTRL-LWCGLALLIYMVMAQTPLFGG--TLVELGIGPIVTAGLLMQLLRGC--EILKFDFKK-PEERGIFQTATKQLMA-SCIIIMFLDELIQKG-----LGCGICLFIMAGVTGGVLLILVYTQGMKIEIPPIKLMYVCNIPVIFGKL--WVELGGLCP-KCAAKNLLDADVQIPGFRRCNQPIEVLLNKYIPCVTIIGCMILGALAGACDVL---GVFG-------SGIGILLMVDILINYYNQLVREQVEVVMPLHCCGAVKFGD---FELCGGGRCYFDLRCVPCHPP--L--VYARAAAKGTGRT--VEG-IVR--YGARALIIDDVATTGGCVIRAAECLRAAGGLFAGRVLKAKKKRQRWCICRYKRREL-GLDRKANPMGGC------PQARGIVLEKVGVEAKQPNCAVRKVRVQLIKNGKCITAFLPRDGAMNFIDEHDEVHVEGMGATQG-GAMGDIPGVRFKVFK--VNGTCLHELVIGK----KEKPRRFQCDDEYMRNLITTCGICIGTQVK--TKFMKQ--FICDTDP-TGTYTLDLEATQGRIKAAAQFIEHT--GACELIVCCGKDCARVPIRKFAELVGCKDIHKRFMPGTLTNPDLPKYME--------PKLLLVCDPQVDAQAVTEATNAGIPVIGIANCDNVTCRLDVIIPANNRGRGALAAIFWLLAR-EV---LVIRKQVVAVRTDLGMGKGKIAAQVGHAWWP-RQEKVVVRVRGPVELEEIKKMAACLGIPWCEVCDAGHTQVEPGTITCICIGPAPECMVDRVTGDMKLRYVFVTGGVMCGLGKGVVCCCIAKLMQLANQKVCCVKIDPYLNYDAGTMNPIAHGEVFVTED--------G-----GECDMDVGNYERFLNQNVPRCHNITTAQVYCAVIEAERDGKYLGACVQIIPHVTDEIKRRIDTLVVECGGTVGDIECLPFLEALRQIRVEDGPQGVAFVHVTLAPCLEVVGEQKTKPTQHCVQELRRIGIQPDYLAVRCKEPLQEKTKEKLALFTNVPKQDVLCCHDAQCVLEVPRMLHGQGLADCYVCVNQALKHDGILAPGGFGTRGCEGIMCAAGFARRNAVPFLGICFGFQLAAVEFARCELGLKGADCTEICCDTPDPVQRCA----SGMGGCLRLGADEIALREGCAARCMY-GCPVIHRRHRHRYEFNKC-YLDRFEKGG-----MLFT----GEC-DGGRRMEVLEV--PC--HRFFIGVQFHPEFCCRPGFPEEAFRNFTQTLEFIMVFKDIDIKK--GFAINETVQLPKTC--SPCTVCVLACGDMGVRAKNAKADMVVDADGLEKLGTNKRECRKFINRYDFFLADTQLMPVVGKVL-GQILGPRGKMPVRVRARACLCLCCKIGDETMDDADLVANAMAVYGTVEKKLPQGCK--NVRQIMVKTCMGMGDPKLP-RRMWRK--PKRPFNYDLKMEELRTLGTFGLR---TKRELWKAHTELCRV-RN--QARCLLARIGLV---GKDACLDDVLNLQVNDLLGRRLQTIVMKKLGFCTPYQARQAVVHGHITICDRVVTIPCYTVYVEEEGDIIIRPHVTEKTFAMVERECKVCFIVRNTACKPEIAEAICIMYGEKATGVNTKKAFVQFGNVE--KARDLATKIGVLGLDGCKGKEITL-PPVFGTPYRRDLIKKAYTILDTHHFQPKGTHPTAGMDVCA------DCLNPPTGHGQARIA-R--MKGGGGRRRGE-AGEVACIRGGRQAHPPKVQKVIHKKINKKEKKLALCCAIAATACKCTVAGRGHIIDG-IEL--PIVICDDIEC-VCKACEVRKILCALGLFADVNRL-EGR-KPRTGKCALRGRPKKIGKCILFVGFPGVTARPARDLCVLDLAPGAEPARLTVYCKAAVKFCHEGDKFEIIVKPDPALDYK--LGR-K-KDLCCVLVCDEIYCDCCKGTKPPDEKLEKAFGTTDPAKIAEIILLKGDFNLTTDQRRRMVEEKRRQIIEYIAKTFVDPR-SHLPHPPLRIEQAMKDGKVCVDPHKDAAEQAKGIVEKLRGIIALKCENLDLEITIPAQYAAQCYCVLKCVG--SLKCEEWLQNGCLKAIL-EIPAAARPGVIDRLGCITKGVRRIREGTVIDHIDGGRG--------LQVLCALGIDG-GDGCL--ITVALNVPCGKFC-K-KDIIKVENRFLKDDDTNRLALIAPCATVNIIRDYKLAEKRRVALPNEIGRI--FRCTNPDCITNCC--ERIECVMDVA-SRE-GPVLKCRYCACQITPRLAHDLKRACRANDAPIWLRLCRLAQKPTRARR--TLNLNKIARYTKEG-----DVVVVPGRVLGTGCMPHK-ITLCPFGICGAAAEKVLCCGGRV--TGFAELTK--EFPTGKGVVLPVRCFTCGNLVADKFGEYKCRV--EAGE---AP-----GKVLDCLGMERYCCRRMLFTCLKIGCYILLPVGDQATGEPCRICEYDTCKPGKHGAAKARIVGVGVFDGQKRPHVGPVCMQVHVPLIDKRTGQVQIMDCETFETGQNVEYWLV-MDKTKI---------------------MGAYGQTEGLLGPEM----NLNELQRLCKIGRIA---ACIECIDK--------VGPFDCKFCLECIDDVRAAKKDDIVRRAIHCCNWIILVEGRAD------VINLLR--AGYDNALAGAK--IDECIKEICDCKDRV-VAFMDGD--------RCGGF------ILKELKTL-VCVD---ECIRADPDT-EVEELTPQR----IAEILEAARNA--GVKCVIGHRCA-KL--ANCMRKITLEKVVLNMGVGQC---GNAVEVAKRALGEIC-GKKPCGRDAHETQRDFGVRKGEPIGAAVTIRGEDAGALA-RRLFE--AK---GGQ-VKGRCFDDFGNFCFGIGEHIDIPGIKYDPGIGILGRIAITCPPEITIVHP-IVRLTLDDYILICGPPGCGKCTLACGLGNFYHQK-GR-VVKTFECPRDLQVDC---GVTQYTRLDG------SFENCADVL--------LLVRPDYTIFDEVRRREDFQTFADLRLTGV-GMVGVVHANAPLDAIQRFIGKIELGIIPCV---LDTVVFVKCGRIEAVYRLELKVKVPCGMVE--HDLAR-------PV-IEIRRF--EDDCLEY-ENLATCKLTGG-RRHPLRT-RRKYEIDRYPNEALCG--AQ--ETVTRKVRGKRTKTALKTIDFVNLAV-QGAKVKKCKIVKVLENPTNNDYRRRGVITRGAVLETEDGRCRVVCRPGQDGAVNAVPAGAIAAEVREMARCKDWVGRTVCEICDEIEGEIR-RRGAKCA------FP--VNTCINEVAAHYTAEPGDGLAIKEGDLVKIDLGAQINGFIADTAVTLVEAAEDALKGAMAMIKEGVKCRDIGRAIEGVIKRHGCKPIANLCGHCLDRYTIHAGRC-IPNCDAYACEPFVTTGDGLGFVREGRTKNILVEANGERVAQAEHTFIPRDDGVTVTTCQ-PRKCG-QECIKYCPIDENLCNG--FGICAKVCPFDAITIVNLAAELACD-KVHQYGPNCFRLYRLPC-PRRGEVVGLLGRNGMGKCTVINILCGALQPNKPQ-----QVQN---VAQAF--DGT-GGELIEKYDER---G-AAAGLIKELDLGCAVDRRTEEMCGGELQRVAVAAAAARDADLYFFDEPCCYNDVFQRAGVARVIQGLAE-A---GRCVMVVEHDLCLLDYLCDHVEVLYGDP--AVYGIVCGVMPAKTGINAFLDG----YLHVENIRFRFRVCVEPGM-VRKGEVLGVAGANALGKTTLMKMIAG--VECPDC------GY-------KPQYL-QGD---SDAEVVAILLCGGELQKVAVAACLLQKADVYALDEPCAFLDVEDRICVAKFLQKYVRCFGRCAIVIDH--------D
Cytophaga_hutchinsonii                                  GAE-VTWCCCNIFCT-----QDAWKGMNEEEFDWCIEQTLFFGEDRKPLNMILDDGGDLTNMVLGICEETTTGVLRLKDRERNGCLVLPAININDCVTKCKFDNKYGCKECLVDCIRRATDVMMAGKVAVVAGYGD-VGKGCAACLRGAGAR-VIVTEPICALQAAMDGYEVK-KMADADIVVTATGNKNIITGEHFKAMRDKVIVCNIGHFDNEIDMAWLNKTYGCTKVTVKPQ-VDI--------YNV-D-GHDVIILAEGRLVNLGC--ATGHPCFVMCCCFCNQVYTLPKCLDEKVARLHLCKIDVELDILCADQAAYIGVTDFAGQDKILENLKIFVG-AAKQR--------GEPLDHVLLHGPPGLGKTTLCNIICNEL-----NCNIKITCGPVLEKP--GDLAGLLTNLQTN------------DVLFIDEIHRLNCVVEEYLYCAMEDYKIDIM-LDCGANARCIQIGLNPFTLIGATTRAGLLTCPLR--ARF------------GINARLNTPI---LETAAFEIARGTPRIANNLLRRT---------RDFAQIKGD--GTITLEI---------NGLDDMDNRILTTIIDKFKGGPVG--LCTIATAVCEEAETIEEVYEPFLIQEGYLKRGQVHIRACFNNIIICVTNCTG-QVICWACAGKMGFRGCKKNTPYAAQVAAQNCAQVAFEGGMRKCEVFVKG---------PGCGRECAIRTIQNAGIEVLTIKDVTPMPHNGCRPP---KKRR????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????VKTIEYDPNRTARIALLCYA---DGEKRYIIAPTGLEVGNTIGPGIAPEVGNCLPLCDIPLGTVVHNIELKPGKGAAMARCAGTYALPCGEMRMVLVVCYACIGTVCNADHMNLTKGKAGAT--RWAGRR---PRVRGVAMNPVDHPMGGGEGRC-SGG-HP------RCRKGLYAKGGKTRRNIGIAAHIDAGKTTTTERILYYAGVNHKIGEVHEGGATMDWMAQEQERGITITCAATTVGWKYRDNQ----YHVNIIDTPGHVDFTVEVNRCLRVLDGLVFLFCAVDGVEPQCETNWRLANNYKVARLGFVNKMDRCGADFLNVCKQVKEMLGCNAVPLQLPILDYVMELLPCPLDKD-----DLVGINPDTD-KEVVRKPVETDPFCALAFKIATDPFVG-RLCFVRCYCGLLECGCYVYNTRC-GNKERICRIFQMHANKQNQIDRLHCGDIGAVVGFKDIKTGDTECMVF-PEPVIGYAIEPKTQADVDKMGVAIAKLVEEDPTLHVHTDQETGQTILRGMGELHLEIIID-RMRREFKVEINQGAPQVAYKECLTKCT--EHREVFKKQCGGRGKFADIVFELCPGGVIPKEFIPCIQKGFEEAMKNGVIAGFPVECMKVRLNHGCFHDV--DCDALCFELAARQGFKEAAKNAGAKIMEPIMCVEVVTPEEYTGPVTGDLNRRRGMMKGMDCKMGA-QVIKADVPLCELFG-YVTDLRTICCGRATACLTFCHYEFVPDPIADYLTKIRNAIKAKHRVVEV-PACNIKKEITKVLFDKGYIQCYKFEE-SGC-IKIALKYH--PLTKEC-------AIVKIERICKPGLRK---YTHAETMPRVLNGLGVAIVCTCKGIMCDKEAKNLNIGGEVLCFVYLDPTKTVKEIVEEGVQEVVDLLKPGDAKIEHLCGGEKRRVALCRLLLQEPLEMFIPAGRRLGCKVILCGGERNRVH-LAMTLKTGANLLLLDEPRWFL----DRVYCDYEENKKKRLGD???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DAAGKTLGRFACQVAGDN-VIIINAEKIRLTGNKMNDKVYTC-HTGHPGGQRF-QTPKETLAKYPEKVLERAIKGMLP--KNRIGGAANPCPPVGPALGCKGLNIMEFCKQFNARTQDKP--GVLLP-VLITV--YTDKCFDFVVKTPPAAILLAEAAKIKK------GCAEPNR-VKVGCVNWDQIRTIAETKMPDLNAFKIECAMKMVAGTARCMGLTVCGKAP----------KVGMTCVYDAVGN----------YVPCTVIEAGPCVITQIKT-VETDGYKAVQLAFDDGQCLAAQDVFVEGDFVDVVGTAKGRGFQGVVKRHGFGGVGGQTHGQHNRARH-AGCIGACCFPARVFKGTRMAGRMGNNRVKIQN------YPEHNLLVVCGCVPGCKNCYVLIEK---G-GIVPELACRAHACTCGPGLLGALLVGVCFCKAFACALHIPVIKVNHMKAHILAHFIGDV----KPCFPFICMTVCGGHTQLVIVRNYLEMEV-VGETQDDAVGEAFDKTAKLMGLPYP----GGPLIDCYAK------QG---NPLAFPFPTVD--MPGYNYCFCGIKTHALIDVLMRKLKRLGGVCANCGLRKAMEQK-REQEGWDVYIPAFEYCTDNAAMIAVAGYHQYLENRIKLKCYDHNLVDKCCERIVRAVKATGAVVCGPIPLPTEKEIFTVLRCPHV-NKKCRDQYQLCTYKRLVDIYCTCCKTVDALMKLEL---PCGVDVEIVTICLACPECILEGCHGEVTQPETINYRTYKPEMGGLFCERIFGPVKDGIICDRCGVEVTEKKVRRERMGHIELVVPVAHIWYFRCLPNKIGYMLGLPTKKLPRENQLLDDKNDTCQQRKA--EARIENKPEWMIIRMVPVIPPELRPLVPLDGGRFATCDLNDLYRRVIIRNNRLKRLIEIKAPEVILRNEKRMLQEAVDCLFDNCRKIN------AVRAE--GNRALKCLCDMLKGKQGRFRQNLLGKRVDYCGRCVIVVGPELKMHECGLPKDMAAELFKPFI--------IRKLIERGIVK-------------ILENVLKGHPILLNRAPTLHRLGIQAFQPKLIEGKAIQLHPLVCAFNADFDGDQMAVHVPLGHEAILEACLLMIA-SHNILNPANGAPIT--VPCQDMVLGLYYVTGRVLFNLVVPDGYLMGLIT-------DNERYNQVNPIYMMMHCGARGCREQIRQLGGMRGLMAKP---------QKNLQG---------SV-GEIIENPILCNFKEGLDVIEYFICTHGARKGLADTALKTADAGYLTRRLVDVAQD??????????????????????????????????????????????????????????????VKGPKGTLTQQVDV--DIKVCVEDGK----VLYRCLICNMVQGVCQGYKVELELVGVGY--KATATNNI----LELCLGYCHGIFLKL--PCEICACALTEKGKNPIVTLECIDKQLIGQVCAKIGLDEAGRGCMAGPVVAAAVDCKKLTIKQRELLRQDIDGLYLCIAAACVLAKTHRDCLMERLAKEHPEYGGNFICDRIKARYE-GDCLIPFLEHDDAMDCRTLLIAEADGVVEFVDANEIKMRDCDIIT-YCLIKFRRTNQDTCINLKPIQHGERVKKGQVLCEGYATDKGELALGRNLMVAWQGYNFEDAIVICEKVVRDDIFTCIHIEEFELEVRDTKRGELTCEIP----------NVCEEAVKNLDE-NGIIRTGAEIKLL----RAIFG-DK--AGDVKDACPPCLRGVVIDTLAKVYIAKKRGDKMAGRHGNKGVVARIVRDEDMPFLENPLGVPCRMGQIYETLLG-------LGRTKLVDGLCGNPFDQPVTVGVIYMMKLGHLVDDKMHARCIGPYCLITQQPLGGKAQFGGQRFGEMEVWALEAFGAANILQEILTVKCDDV---------VGECFNVLVHELRGLALEITLDTGLLVDALNGAPGVYGAVNGTILTERHGEK-GFGYDPIF-QP-------NGYT-TCFAEMCMEEKKTCVARVYLQCGKGCIVVNKTYFKTEPLQICVECPDINVNVQGGGVTGQAEAIRLGIARFKCPLRKEG--LMTRDCRMVERKK--YGKRKARKRFQFCKRKKYECECIKFYIEGIY------LLF---AAGVTYPVLADI----------------------ALIVNNGNIF--IYLNK-----PCI-----PCRLFRN-EQDAVVHHRDDFPKG--NDKTMPGFPYHPHRG-----GAAGRFCGGDVQWMTAGKGVLHCEMFPLVHCDKGNPMELFQIWLNLPK-RCKF-VQPHFKMLWKENI-------------PVLNEMDCNGNKTEVNVIAG----------NLKFCGPRGVGKTTNARILALAGIAVKE-------NIKAEKEALHLIAQKADGALRDALCMFAKPKKRYLLPDPKF----------------SDTMVTKFVNCLMGKKCTAYCIFYDAVALVEKKTCECGLEVWKKALNNVCPQVEVRCRRVGGCTFQVPTEVRPDRKMALGMKWLINYAR----SRGEKTMTDKLAGEIICACKGE----GAAVKKRDDVHRMAEANK?????????????????????????????????????????????????????????????????????????????????????????????---------------------------MCR-SLKK----GIKTWCRRCMICPEFVGHTFAVHNGNKFIPVYVTENMVGHKFGEFCPTRTFKGHAAKGKK-----------ADNCGAKEVLVIRVLG----GTGKRY--ACIGDKVVVTVKCAICCCNMKKGTVCKAVVVRTKKEVKRADGCYIRFCDNAAVLLNNN-DE-PRGTRIFGPVARELRDKQFMKIVCLA???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????-----------------------MCQVNVKTVKACE----IELGRRFCFCAIVVVGDGHGVVGHGLGKANEVTDAITKAIDDAKKNLIKVPVING----------TLPHEMIGKYCGGFVFVKPAAPGTGVIAGGAMRAVFECAGIKDVLAKCKG------SCNPHNVVKATIDALKYVLARIPKGGICKIVIERT-IKRVTLTINTARPGVVIGKGGAEVDKIKEELKKITG--KDVQINIFEI---KRPEMEALLVGECIAQQLKARIC-YRRAMKQAIAGTMRV-GALGIKIKLCGRLGGAEMARTDQYKEGRIPLHTLRAD--IDYAVCEALTVYGKIGIKVWIFKG--EVYGKR?????????????????????????????????????????????????????HAGTLDPLATGLLIVCTGKKTKTIECLMADEKEYFLGTITQIPPIHCAVIKCRQVFIKEFKI--TGTYIRTIANDFGKALGCGGHLNALRRERIGTLCVKQA--LTP----------------------------------------KFL?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????LLKIEAVRLRPEEPFKWACGWNCYCDNRLTLCFPP--M--IYVRPKPKGMQNL--IEG-KIT--KGQKIVVVEDLICTGGCCLKAVEALQEGG-MPTIQQLVRKGREQL------------VFKCKCPALDCC------PQRRGVCTRVYTTTPKKPNCAMRKARVRL-TNCKEVNAYIPGEG--HNLQEHCIVLIRG-------GRVKDLPGVRYHIVRGALDTAGVNGRKQCRCKYGAKRPKP-IEYKDLL-----DAGVHFGHLTRKWNPKMAP--YIFMEK--NGIHLIDLNKTLVCLDEANAALKTIVRCGRKVLFVATKKQAQEVVTAEAKRLKMPYATERWLGGMLTNEKLEKVLGGIADLTRLPAAIFVVDVKKEHIAIAEAKKLGIPVFAIVDTNCDPTIVDFPIPANDDAFKCICILTQAIGQ-GIEDALCER???????????????????????????????????????????????????????????????????????????????????????????????KYIFVTGGVTCCLGKGIVAACLAKLLQARGFCVTIQKFDPYLNIDPGTLNPYEHGECYVTDD--------G-----AETDLDLGHYERFLGTPTCQGNNITTGRIYNTVITKERQGAFLGKTVQVVPHITDEIKRNIDIVITEIGGCVGDIECLPFLEAVRQFRWEMGPTDTLVIHLTLVPYLNAAKELKTKPTQHCVKLLCETGIHPDILVCRTEHPLPAELRKKVALFCNVNINCVIECIDAETIYDVPLLMKKEKLPDAYKCICEAFIHDGILVAPGFGERGLEGKIAAVEFARENNIPFFGICLGMQCAVIEFARNVLGLKDANCTEMNKDTANPVQKNV----TMKGGTMRLGAYPCELTKGCKAHAIY-GKCKIMERHRHRYEFNNK-YLKQYEKEG-----MLAT----GIN-PETKLVEIVEL--RD--HPFFIGCQFHPELKCTVENPHPIFTKFDACVDIDVRL-GVDPKK-ADQMVRGIVTLPHGTG-KDVRVLVLCTPDKAQDAKDAGADHVGLDDYIQKIEGGWL-------DIDVIITMPTVMAKVGK-L-GKILGPRNLMPIDFKVDKFGIVHTCVGKVCFCPEMILENANEVLQVLAKLKPACAKGTYVRCITLCCTMCMA--------RYTG--PR-----------SRICRRFGEPVMGDCKALQKKNYAPGMHGRN--KKRKQVLERQFAKTFDTAARKQGITGENLLKMLEARLDNTVYRLGIACCRRAARQLVIHKHIVVNGDVVNIPCYQLKPGDQLGVLKKPLITEKVCAQNE-GGVYGFVVDKNANKVAIKQAVEKMYGVNVEEVRTKKAIVKVKDG------EIIDFYG????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????IDQIQQCIDVVEVIKR-----KGHYCGCCPFHNE------KTPCFTVTPAKGIYD---SMLVVTNY--------ACQYYTD-QLWNCEDGKCIGLCYFKERGIRKEEECLLVEGYTD------VICLHQ--SGVENVVAGTC--LTEDQIKLVKRYTPNITILYDGDAAGLKACLRGVDL------ILQQDMNV-SIVV---FPQGEDPDC-YVQKIGPTAFKDYIKCNKDLLCTK-----FQLCDNWE-KFQIDVPMQVPKITKIVINKGIGAAVADKKLVDVGVDELTLIC-GQKAVATKCKLDVCNFKLRANMPIGAKVTLRGNHMYEFL-DRLTAVALPRVRDFKGINDKGFDGRGNYTLGVKEQIIFPEICIDKINKITGRVCVLPTLVMRLLNQDATNINIETLILICGPTGCGKTTTLYATLKLLNKT-TR-NILTIEDPVEYTLEGV--NQAQLKENIG-----FNFGCALKTF--------LRQDPDIIMVGEIRDQDTANMAIRLCLTGH-LVLCTIHTNCAWGTVARLI---DMGVPPFL--LAGTLCVCVAQRLVRLLCPHCKQQTPFCATDYPKGFKA-------PMHVDVHYI--STGCEQC-F?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????CGKILGKAHAEIAKIIRPGVKTNELDKIAYQFIA-DNGGIPC------FPCTLCICVNEVVVHGFP---SEYELKDGDIICVDCGVKYNGYHCDCAYTLLRVTKECLYKGVEQAIVGNRIGDIGFCIQCFVEKEGYCVVRELVGHGLGK-SLHEKPE-VPNNLVIAIEPMIN--LGKKNVVQENDG--IRTCDKMPCAHFEHTVAVKKGKPEILT------------------------------------MNILCIDNLCKAFCDKKLID----------GITLGLCKGEKVAIVGRNGAGKCTLLKIVMGLEQADLYE-----ECMVTLDCDDME--KAITMMDALQAWEFE---D-KAKRILCKLGLQDA-NLEVQNLCGGQQRRVALARVLLQEPDVLLMDEPTNHLDLDMIEWLEELLKACQQ-------TLLFITHDRYFLDEVANGILELEKYP--EYLERKAEEEAIRNACLEKVTN----TLRKEAEWMRKKILTDFNYIFRKNEKLGIIGKNGCGKTTLLQLINR--AIQPDC------GY----------YTQKGLTFKPRQKVIELVLCGGEKKRLHLLTILVRQPNFLILDEPTNDMDLC----TLCVLEDYLENYKGCLIIVCH--------D
Desulfurococcus_kamchatkensis                           GAE-VVLAGCNPLCT-----QDAWRGQCCCEYYWCLEKIIE-----WRPQIVLDDGADLHALIHGGTEETTTGVIRLKALEREGLLKYPVIAVNNAYTKHMFDNRYGTGQCTFDGILRATNILIAGKIVVVAGYGW-VGKGIAMRARGLGARRVIVTEPIRALEAIYDGFEVM-PMCEADIFITATGNKAVIRREHFEKMKNGAILANAGHFNVEVWIPDLEEL-ARCKRHVLPY-VTE--------YELRD-GRKIYLLAEGRLVNLVA--AEGHPCEVMDMCFANQVMNPPLELDEMVACLKLECMCVRIDCMTREQEEYVKCWDIGDLDEVKQKIREIVE-LPLKYPELFEHLGIEPPKGILLYGPPGTGKTLLAKALANEI-----GAYFVTINGPEIMCKFYGECEERLRKIFEEAQANAP------AVIFIDEIDCIAPKREEVTGEVEKRVVAQLLTLMDGLKERG------KVIVIGATNRPDALDPALRRPGRFDREIEIPPPDKRARREILGADIAALVKEAAMNALRGPPGTGKTLLAKA---VATECGANFITVRGP--EVLCKWVDEIDCIAGIRGCD--PCGVIDRIVNQLLTELDG--IQPLRRVVTIAATNRPDLLDPALLRPGRFDRGVAHIYCCPNNTIIHITDICGAETVCRICGGMVVKADREKPCPYAAMMAAARAATQAMDKGITALHIKVRAPGGH-GPKTPGPGAQAAIRALARAGFIIGRIEDVTPIPHDTTRRPGGRRGRRGIAGRYGTRYGCTLRKKIRDILEKRYCPHTCPFCGHKGKVYRLCTGVWACKKCGAKWAGGAYMPVDKGAVQALLRGADLMVPGIRCIIGDFKVGDIVWKAVKILHHLNDYHYIAEAWKEKCR--ELEALIRQRLIEWRREPCVVRLEKPTRLDKARALGYKAKVGFIIVRVRVRKGGQRKPRPDCGRRPKRMGVYGYAP-AKCLRLIAEERAARKFPGLEVLNCYYVAEDGRYKWYEVILVDPHHPCICNDPDVNWICEPQNRGRVFRGLTCAGKKMRGLVEDLVHDPGRWVPLAQVKLE---TGLVFYVPAVEGMYAGQIIGPGAKPVNGNILPVGMIPEGMQVVNIEKRPGDGGKFVRACGTYALPCGRVIEVPNECRAMIGVIAGGGRLEKPLLKAGAAYYKWCAKCRVWPKVRGVAMNAAFHPHGGGCHQH-VG--RPCTVAR-NTPPGRKVGHIAARRNIGITAHVDHGKTTLCDTLLCAAGLICE--KIAGQALALDYLDVEQKRQMTVKAANACLYHEYKGKP----YLINLIDTPGHVDFQCKTIRALRVIDGAIVVVDAVEGVMTQTEMYLRVALEERVRPVLFINKIDRLIKELRLCPTEIQQRLVQIVRDVNTLILDMVVKHIPNPREAQRYRIPKIWHGDPNHEIVKYLMEADPNGPLVMLINDIRVDPHAG-LVATGRIYCGTLRPGEEVWLVNA-RVPQRVLQVCLYMGPYRELADEITAGNIAAALGLEKARCGETEKLKMITECVVTVAIEPKNPQQTTKLIDALYKLHLEDPCLIVKINEETGEYLLCGVGTLHIEIALT-LLKDLYGLEVVTCPPVIVYRETIRDRC-QVFEGK------SPNKHNKFYICVTPGVQYLREVKDTIIQGFRLAMREGPLAMEPVRGVKVVLHDAVIHEDPAHRGPAQIFPAVRNAIFAGFLTARPTILEPILKLDIRCPMEYIGNICCVITKKRGKLIEVQQMETT-ARVIAEIPVCECFD-IADMLRNVTAGKAIWGQEFCRWAPVPDTLANALCAIYNAEIRAKKEVVVWPACKLTLNVLKVLQREGYIGEFEYID-DGK-IKIQLLGR---INKIG-------VIKPRYPVKHRELAEFPEWLK-RYLP--AYNIGVIIVCTPYGVLCHKEAVEKQTGGVLLAYCYGDVQVVVVGPPNTGKCMLVNRLTPPLC-----RDCVFTNRVIG-LARNADLE-------EYRIYNAIGEVLFDQLELIRVYTKCPNTPPC-EKPFLY-----AKIGLEHIVED----GDMVTALEVPADKLIERLVEYLKANVPEVKPPTWCMFVKTCCHKEKPPTNP-E-WWYYRAACILRKLYKAGEPVGLTELRREYGGRKN--RG--VRPERTVRAPGNAIRKILQQLEQAQLVRRTRK---GRILTPQGKCLLDRLCDACNQILGRLACIIAGYR-VIVVNAEKAMVCGEKNRVLEGYK-ILFRVKTHYNPETKGVRRPRTPANIFKRTVRGMLPI-DKPKGGKATPGPPLGPTLCPYKVNIPQVVKAINDATKDFE--GLCVP-VEITI-DIDTKEFEVRVGIPTTTALLMKEAGAKQ------PTGDPAH-QKIGNICFEQVVKVAILKRDCLTAKTLRAAVKTVLGTARCIGITVDGKDPKEVQKLVDEGKAGMTHAIIVEDRPNTPVTGKEVFTPVTILDAPPIVVLGVRT-YIIDEEGY-LKTKGEGGYVRACDVFMEGQFVDVIGVTKGKGFQGVVKRFGVKELP-RWHKHRKGCRK-IGARCP---GFGTMCEPPQAGQMGFHRRTEYNGFLHYGLVYGPYIMLKGTVFGPAKRMLILRHPIRG-GIHPREACQHHTVAVGPGIGPCLRVGATIARFLCKYFNIPLTPVNHAVAHIEIGKLFC-----GFNDP-VIVYVCGGNTMVLVQKN-SQYRV-MGETLDIPLGNLFDTFTREIGIAPPYVVDGKHAIDVCAE------WC--QEFQPLPYTIKG-----NDLCFCGLLTETAFNMLIEVCERVGGVACNKVLRWKMETL-TCIYNVKYYGTPPDVAGDNGVMIAYTGLLLYLYGKIKIWCTNVKVLDDFVGKITDIVKKTGVKMNGPIPLPTKKLRIRTMKLPHGEGKKKYEKWEMRIHKRLLYI-AEDERVMKQLIRVRI---PPEIWMEIIKFGILCPDEIRKMCVTQIFCCEVYDNDGC-PIDGGVMDRRL-GAIEPGETCPICGNTRDCC---PGHFGHIELAKPVIHAGFAK----QILIYLKATCRNCPH-------CRGRLEKICN--DDR----PEWMVLTVLPVPPRCVRPCVLLETGIRCEDDLTHKLVDIIRTNNRLREHVEGGAPCAIIEDEWELLQYHITTYFDNEVPGL------PVAKHR-SGKTLKGIAQRLKGKEGRFRNNLRGKRVDFCARTVICPDPCLCINEVGVPEDVAKILTIPERVTPWNIEEMRKLVLNGPEKWP-------GANYVERHLMDGDIVLFNRQPCLHRICVMAHVVRVLPYKTFRLNLLVCPYNADFDGDEMNLHVPQCEEARAEARLLMLV-ERHILTPRYGGPII--GGLQDYICGAYILTGKQLVCLFLPDGYKRGELLARPGKTVEETLEDEINPVVIMARTGARGNPVNLTQMAALLGQQTVR--------GKRLTRGRALCHFKPEDL-GPEARGFIACGFVHGLNPVEMFFHAAAGREGLIDTAVRTCQCGYMQRRLINALQDMAQ--VLVIVRVLPEDVETPLDELE-PIAFGLKALRLAIIMPEQTEGGTETLENLICQVQGVVKGPKGIITRDFCHARGVFIRLEDRV----VTIAAHIRNMITGVVRGYRYKLKIIFCHFPITVCVDEKNKVVRIRNFMGEKCDRIAKIY-G-NVKVKV---SG-ED-IIIEGVDIEEVGLTAACIGVDEAGRGPFIGDMVIAGVDCKLLEPLKRLMILNNMDAKYPAVCAACVVAKILRDCNIKALQV---IAGGRIRRPLIVIE---NGGIVEYLDPDEGITACIIPYPEHNQCPRNMYQCAMAKQGLYAAN-FQRRMDTRGHFLHY-PQRPVETRMMNVIG--YNERPA--------GQNMVVAYTGYNMEDALIMNRCCVERGLARCTFFRLYTTVEYKYPGGD-EITIP--STNVR--GYRGQKAYEKLEE-DGIVAPETQVRFLCTQEYEVGG-LT-----RQDTCRHEEKGIVDTVLIKVRVRDLRGDKFACRHGQKGVLGLLLPQYDMPFTENPHAFPCRMAQLMECIAG-------KGEEAMYDGRTGELIKTPVFIGIVYYQKLHHMACDKIHARARGPVQILTRQPTEGRCRAGGLRWGEMEVDCLIGHGCALLLKEAMTDRCDCTIIYVCEL--CGYAFKLLLQELMCMGIRPRLDAGLFIRALNGFPGPYGEVCGYITTTPRGNK-GFGFDPVF-AP-------REQPYRTFGEMDVEEKKTCIARAVIKPGIGRVWINEFIQF-ELAKMKILEPDIRVNVHGGGYMCQAEAVRIAIARVKCLFKEYDRHMLCGDPRQTEPKK--WGRYCARRRWQKCYRTRNLVPGHRVYGEREWNLYRCKLLYLGIACGTTACHICDIVGLKGRIYGVEFAPRVAQPDQAAIVADNGYLL--LAIKA-----RCIDVTKEPCEVYRR-EIETLVFYNPQAIVC--RDDIDPHALYYIRKNDLDPYGCPVPFVDCVFKP-LGKRALIGVTATDTAPLTCCHYRKTLRRYWFTCV-HTDFEKEIGARLLIAYIVKHACALDIAAR--PLLIFIYKHYYRVFFETLRCTGEAYRLINECLGLHGPPGCGKTCLVEALALKRICCAE-------KLVCEDQALDEIAKRCEGDLRCAINDLDPCLKKYICLKPVYLPHCGGRHEHKRFGKALVPIVERLINNVMGKKHLAYNIVKKCFELIYLKTGENPLQVLVRAIENAAPREETTRIMYGGITYHVCVDIAPLRRIDLALRHLTEGARLKA-FHNPICIEEALAEEIALAACND-PK-SYAVQKKEEIERIALCCRQGRTRTMGWGRVGQHRKCGCRGGFGAVGF---HKHKYI-WIIKHAPN-----WYG--KHGFKVLGCGKVTRGLKVIAREITEEAKRKIEEAGGGKCLEELL------NMCMDELVMLLPARQRRCLKR----GIKTHVRDMVVLPEMVGLTIAVYNGKEFIPVKITPEMIGHYLGEFCPTTKKVTHGEPGLKATRACRFVAMKADNCGAKEVMIIGVPG-Y-HGRLRRVPPAGVGDLVVVCVKKGIPE---MRKKVFKAIVVRQRRPYKRPDGTWVAFEDNAVVILTPE-GT-PKGTEIRGPIAREAAER-WPQIANLARLAADLLGVGVCRIRV--DPGRIEDIEAAITREDVRRLIKEGAIWVAPKHGIAGYCCKVRHKQRV-KGRRRGHGKRKGCKTARL-DEKEVWMNKIRKIRRYLRYLRDRKL-IDARTYRRLYMLAKGGYFNCLCCLWVPRTRVGKMVLEGKITCLKEVFDRNLPLLEPEIVDYLL-PDLGRRTRFLVVVVIGNENGFVGIGTGKAKQYVDALAKAIRNAKLNITPVRRGCGCWECRCGEPHCVPFTVRGKCGCVEVVLKPAPRGTGLVAGDVAKVVLRLAGLRDVWTECFG-----ETRTTLNFAKAVVNALEFLAHYFKDAGYADVELYRT-PTGYRVVIHAEYPGRLIGRGGCVIKKLCTILQNKFG-LDNVNITICPV---IDPDLNARVVAFRIVRALEKEIP-FRRVMMYMLKRVMDA-GAIGAEIIICGKLRG-ERATYEKLKAGKVYKAGEPVEYMVDRAVVKALLKPGIFGVEVVIVKP--GIKMPDLRKILTPEARERLNNLRLVKPELAEMLEQQLIALAQCGRVKIPITDEFLKRLLHGGTLDPKVTGVLPIGLANCTKVIGNVIHCVKEYFKGDIYQKPPLRCCVRCIRVRRIYEIEL--LGTYMRKLAHDIGLMLGTGAHMRELRRTRTGPYREDETL-VRLPVETCIAHLPKIMILDTAVDAIAHGANLAVPGVAILTLKGELVPTAVKPQGKPCMYERL-FWTGVALIVYMIMANTPLYGG--TLMELGIGPIVTAGLIMQILVGA--KLINLDLTD-PEDRKVFTACQKQLFV-ACYLVIVLDETIQKG-----IGCGVCLFILAGVTIVIMFILVYLCNMKVEIPPLQFLYVTNIPVLFGLM--WVEVAGLNP-AAQAEQLICCGFEVPGLRNNPKILEKILAKYIYPLTVLCCLIVAAIAVLADAL---GAYG-------TGTGILLAIGILQQYYALIAYERTLEAYPLYKRGMVKIGR---FKLCCGIECYIDMRRLYMYPP--M--AYVRVEKKGTCCL--IEG-DVT---GLRTLILDDVCTTGCCILKAVEAILEAGGLYAARKLEEKRLKFRWCQRDFKKRMLRKMGKLRDPLEGA------PMARGIVLEKVGIECRKPNCAVRKVRVQLVKNGKVVTAFVPWDGGVNYIDEHDEVIIEGIGGPLG-GCLGDIPGVRYKVVM--VNGVCLKALWLGK----KQKPVRLVPIEKYL-----SAGVHIGTHIC--TKFMEP--FVYRVRC-DGLYILDVRKIDDRLKIAGKFLARY--QPEKIAVVCVRQYGRKPVQKMCQYVGCKPFVGRFLPGTFTNPCLKIYFE--------PDVVVITDTRCDMQALKEAAETGIPIVALADTDNRVDYVDLIIPGNNKGRKCLALIYWILTR-QI---LREKKQVIVVRCDLEMCKGKIAAQVAHAWWNCGQKKIVVKVRGEEELVKIYMEAICNGLPACIVRDAGLTELPPGTITAVAIGPAPDDRVDKLTGGLKLKYVFVTGGVLCGLGKGIVAACTGLLLKCMGYRVTAIKIDPYLNVDAGTMNPYMHGEVFVTED--------G-----GETDLDIGHYERFLGIELCRKNNITCGQIYYCVICKERKGEYLGQCVQIIPHVTNEIKERIDIAIVEIGGTVGDIEGLPFLEAARQMRFEEGACNTLYMHVALAPVLCC-GEIKTKPIQHCIQELRRIGIQPDIVVARCTRPLDPEARYKIALFGNIPVEAVFCNPDVDLVYRVPLVLHCEGIRDCYICIVEALRHDGAVILPGFGRRGCEGKIRVIKAFREADKPLLGICFGMQLMVVEAARNMAGLENANCCELDPCTPHPVQRNL----NQFGGTLRLGCRKIVIEPGCLAWKIY-GVREVFERHRHRYGLNQK-YIDMLEKTG-----LRIT----GWC-EEG-YAEIIEL-KDC--NVFYYGTQAHPEFKCNPLKPCPVYRRFKQCVEMIVVLRDIDVKG-QAGKIREFITLPKGRG-KELCVCVIGDEELAVKAREAGAKIVLTCQDLQGL--SKKQAKKIAGQCDWVLVRTDLMALTGRTL-GPALGPRGKAPVAARVKDQPQIMVAIGAEDMCPADLAENALAVLCVIEQRLPCGAG--NIAKLVFKTTMG--------------------------MYEMKLMGTYGLR---NKRELWKTATMVRYY-RH--RARCLLIKLGLL---KEGARLDDVLNLKIEDLLERRLQTIVYKKGLAKTLHEARQLIVHGHIAIGGRRVRCPGRIVTVDEEPLVIIRPLQCEKALTLIDKQNTLTFIVDIDACKTEIKRAVEELFNVKVEDVRTKKAYVKLAPEY--KACEVACQLGVYGVNGNVVGEIEL-PELFNVPIRRDLIRRAFLCAFTAMLQPKGRDPLAGKRTTA------KYWGV--GYGLARVP-R--LPNGT-------ARFVVCTRKGHAAFPPRPDERIHEEVNKKERVMAIICALAATCRPELVRERGHVFTP-GRL--PVIIVDEAECCICKTTQVREYLEKIGLWCDVERCLDGM-GIRAGRGKMRGRTYVEPRCILFINLPGVDIATPGNLCILHLAPGGVPGRLTVICMKAARYEAKGHRFEILVDPELALKIK--EGK-Q-ICIDEVVAGDFIYKDARKGLKACPECMKEVFGTDDPKVVAVEIIKRGELQLTAEQRRKFIEEKRAQILNLIARNAIDPK-TKLPIPVKRLELAMEQARICIDPYKPAEQQMEHIVCQLAKVIPIKIAKAYVAVRIPCEYACRCLKQIQAMG--TTKKVQWREDGCLYVEL-EIPAGLQQELIDKVNALTKG?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????TNIVLRKVIEELRKQACINNAPIWCCIAEELCKPTRRRR--AVNICRINRYCKPG-----DVVVVPGKVLGAGNIDHP-VTVAAFGFCRTALEKIVKCGGRA--IFILDLVK--ENPTGCCIKIPVRCFTCGKPIGHLWEEYIKRV--ENGE---NP-----AKVLDDLGVKRYCCRRMFLCYLKVGCFIVI------DGEPCRIVEMCRAKTGKHGCAKANVVAIGLFCKAKKTLVAPVDTQVEVPVIEKHVGQIQVMDMETYETGCEVEYWVV-MGKRLIKYLIRARIEIDGVVDI-----IGAFGQTEGLFGNEF----DLRVLQDKGRIGRIA---ALIETVDK--------VGPYDACICIVDIVDLRMEKIKKIMERTVDKAEEIIIVEGRAD------VINLLR--YGYTNIIAGARR-VPDTIKKLAELKKT--TLFVDGD--------HGGDL------IMKEVLRN-AKID---YIARAPPGR-EVEELCCRE----IEEALDAVVEK--RVKILIGARLG-KI-TFKTMLKPFIAKVTVNIGVGAE---SDRLPKAMKVLEELT-GAKPVPRKAKKTIKDFGIKKGDNIAVVVTLRRGKAIEFL-RKVFE--TI---GYR-VRECCFDDYGNVCIGVKEHIHMPGVRYDPEIGVFGRIVITRPPEITAVRP-LKKLRLEDYILIAGAPGMGKTTFAQALAEYYMRM-NR-VVKTIECPRDMILPP---DITQYCKHYA------DTGELHDIL--------LLCRPDYTVFDEMRNDEDFKLFADLRLAGI-GMIGVVHATTPIDAIQRFIGRVELGMIPCI---IDTVIFIKNGQIDKVYEVKMTVKLPTGLRE--AELCR-------PV-IEVKDF--LTGELEY-EGNDLRKPTGG-LKGEKRG-KRKYELGCPPVNTTLC--SCE-EKIHVRTFGGGVKYKLKKALYINIAVPDDKTVKKVKILDVVETPCNPQNARFKIICKGTIVKTELGLVKVTCRPGQDGVLNGILAGWIARAVREEAVKLVKPGMCFLEIAEHVENRIR-ELGGEPA------FP--VNIGVNQVAAHYTPVPGDTGRIPDGCVVKIDIGVHVKGYIADTAATLVEACRLALERVVEAVRPGIKANEIGRIIMETIKCMGFNPVRNLCGHCIDQYMIHCGLC-IPNG-VYAVEPFAC--TGVGLVEEGKQVTILLEKCNGIVCQFEHTFIILHREVIVTTCK-PDKCC-LECIRFCPIYEETCIG--CGICVKKCPFNAICIVNLPDELEKI-LVHRYGENMFKLYNLPA-PRTGGILGVIGRNGAGKCTCIKILAGQIKPNKPQ-----YIEA---ARRVL--KGC-VRELIMKADER---G-LWRDIIDELNLCHLLDRKIGELCGGELQKFLVAAVLVKNGNAYFFDEPCCYLDIRERIRVACAIREFCN-Y--EKNYVVIVEHDLMVLDYMCDNIVVVYGEP--GVYGIVCKPYGTRTGINHYLKG----YLPAENMRIRFKLRVEPGE-AYAGEVLGIVGPNGVGKTTFLKLLNG--EIECPE------KV-------KPQEL-SPKVF-SEETVMANLLCGGELQKLAVAVALARDADLYFLDEPCAYLDVEERITTAKTIRRMVEEKGKTALVVEH--------D
Escherichia_coli                                        GTDIHAFAGRQPFFCYPRVLGH---TVQCGQRYCVIPCIPC-----GECAACREEKTNCCERV-GVHQD--GGFCEYLAVREDNLVPLPD-EVCDCAGALV--ECFAIGAHA---VRRAE--IKAEQNVLVIGAGP-IGLATAAIARAKGAH-VVVADAINAFNPTQEDF-IA-ALREACVVLDATGNKACMCHD-VNLIRHGGKIVFIGLYIGELV-------------------IDD--------PTFHK--KETTLLC-------------SRNATREDFALVIEFFCVGEDYQRNV---------VENKNMVKGVITF----EYVGQPQVRCQMEIFIKAAKLRG---------DALDHLLIFGPPGLGKTTLANIVANEM-----GVNLRTTCGPVLEKA--GDLAAMLTN-LEPHD-----------VLFIDEIHRLCPVVEEVLYPAMEDYQLDIM-IGEGPAARCIKIDLPPFTLIGATTRAGCLTCPLR--------------DRFGIVQRLGLEMC---DDGALEVARGTPRIANRLLRRV---------RDFAEVKHD--GTICADIDA-------EGFDYMDRKLLLAVIDKFFGGPVG--LDNLAAAIGEERETIEDVLEPYLIQQGFLQRGVAHIHACFNNTIVTITDRQG-NALGWATAGGCGFRGCRKCTPFAAQVAAERCADAVKEYGIKNLEVMVKG---------PGPGRECTIRALNAAGFRITNITDVTPIPHNGCRPP---KKRR????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????VERLEYDPNRCANIALVLYK---DGERRYILAPKGLKAGDQIGVDAAIKPGNTLPMRNIPVGCTVHNVEMKPGKGGQLARCAGTYVLRCGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAA--RWRGVR---PTVRGTAMNPVDHPHGGGEGRN-FGK-HP------VTPWGVQTKGKKTRRNIGICAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITCAATTAFWCGMAKQY-EPHRINIIDTPGHVDFTIEVERCMRVLDGAVMVYCAVGGVQPQCETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAILDAVIDYLPCPVD-----VPAINGILDDGKDTPAERHACDDEPFCALAFKIATDPFVG-NLTFFRVYCGVVNCGDTVLNCVK-AARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTERMEF-PEPVICIAVEPKTKADQEKMGLALGRLAKEDPCFRVWTDEECNQTIIAGMGELHLDIIVD-RMKREFNVEANVGKPQVAYRETIRQKV-TDVEGKHAKQCGGRGQYGHVVIDMYPGGVIPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGCYHDV--DCCELAFKLAACIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLCRRRGMLKGQECEVTG-VKIHAEVPLCEMFG-YATQLRCLTKGRACYTMEFLKYDEAPDPIADMLTRIRNGQAANKAAVTM-PCCKLKVAIANVLKEEGFIEDFKV---EKPELELTLKYF---QGKA--------VVECIQRVCRPGLRI---YKRKDELPKVMAGLGIAVVCTCKGVMTDRAARQAGLGGEIICYVAPQEIVCLIGPNGAGKTTVFNCLT---------GLPGQQIARMG-VVRTFQLK-------TPCFRRALAYGDQRRLEIARCMVTQPEILML-DEPMKLVMGICDRITPEQIRNN----PD???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DATGKTLGRLATELAGDY-IIVLNADKVAVTGNKRTDKVYYH-HTGHIGGIKQ-ATFEEMIARRPERVIEIAVKGMLP--KGPLGGMANPCPPVGPALGQQGVNIMEFCKAFNAKTDCIEK-GLPIP-VVITV--YADRCFTFVTKTPPAAVLLKKAAGIKC------GCGKPNK-DKVGKICRAQLQEIAQTKAADMTGADIEAMTRCIEGTARCMGLVVED-------------KVGMTRIFTEDG----------VCIPVTVIEVEANRVTQVKD-LANDGYRAIQVTTGAGQCICV-ELFADVKKVDVTGTCKGKGFAGTVKRWNFRTQD-ATHGNCLCHRV-PGCIGQNQTPGKVFKGKKMAGQMGNERVTVQC------DAERNLLLVKGAVPGATGCDLIVKPAVKG-GVVPELACRDHAYTAGPGLVGALLVGATVGRCLAFAWDVPAIPVHHMEGHLLAPMLEDN----PPEFPFVALLVCGGHTQLICVTGIGQYEL-LGECIDDAAGEAFDKTAKLLGLDYP----GGPLLCKMAA------QGTAGRFV-FPRPMTD--RPGLDFCFCGLKTDAVVDTLMIKCKRAGGVCANRTLRAKLAEMMKKRRGEVFYARP-EFCTDNGAMIAYAGMVRFKAGRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLICPHV-NKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDL---AAGVDVQIIKIALACPDMIRCWCFGEVKKPETINYRTFKPERDGLFCARIFGPVKDGVICEKCGVEVTQTKVRRERMGHIELACPTAHIWFLKCLPCRIGLLLDMPLRDIEE-------FETKRKKLTK--RIK----PEWMILTVLPVLPPDLRPLVPLDGGRFATCDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGR------AITGC--NKRPLKCLADMIKGKQGRFRQNLLGKRVDYCGRCVITVGPYLRLHQCGLPKKMALELFKPFI--------YGKLELRGLAT-------------ILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAYNADFDGDQMAVHVPLTLEAQLEARALMMC-TNNILCPANGEPII--VPCQDVVLGLYYMTGRAILWMIVPDGFQCGLVT-------AGERYNKVNCIYMMADCGARGCAAQIRQLAGMRGLMAKP--------DGCIIET------------------PITANFREGLNVLQYFICTHGARKGLADTALKTANCGYLTRRLVDVAQD??????????????????????????????????????????????????????????????IKGKNGELTRTLND--AVEVKHADNT----LTARALLNCMVIGVTEGFTKKLQLVGVGY--RAAVKGNV----INLCLGFCHPVDHQL--PAGITAEC---PTQTE-IVLKGADKQVIGQVAADLGVDEVGRGPLVGAVVTAAVDCKKLCEKRRLALCEEIDCRVPEICAACILAKVTRDAEMAALDIVFPQYGGHFVEDLVTCRC--KGCLIPFLEHDDAVDCGVTAVAKRGGVVQYVDACRIVIKGEAGIDIYNLTKYTRCNQNTCINQMPVCLGEPVERGDVLADGPCTDLGELALGQNMRVAWNGYNFEDCILVCERVVQEDRFTTIHIQELACVCRDTKLGEITADIP----------NVGEAALCKLDE-SGIVYIGAEVKLL----RAIFG-EK--ACDVKDCCPNGVCGTVIDVIVKVYLAVKRGDKMAGRHGNKGVICKINPIEDMPYDENPLGVPCRMGQILETHLG-------MGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARCTGCYCLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKCDDV---------NGECFNVLLKEIRCLGINIELDCGLAVDALGGAPGIYGCWPGVITREPAGTG-GFGYDPIFFVPC------EG---KTAAELTREEKKCCAARVFIKPGNGKIVINEQYFGRETARMVVRQPDLYITVKGGGICGQAGAIRHGITRLRCELRKAG--FVTRDARQVERKK--VGLRKARRRPQFCKR?????????????????????????????????????????????????????????????????????????????????????????????????????????ILW---------QDDLCAQMIDRAKQADLILFHAVLEWV--------------------------ADPRCVLQTLWCVLR-------PGGVLCLMFYNAHGLLMHNMVAG--------------------------------NFDFCGTRGVGKTCIARLLALEHILNEE-------HIAHEPRALQLLARAAEGCLRDALCLTRVIGQRKILPDPKF----------------GCELLAKFVNILMGKKCTAECIVYCALETLAQRCGKCELEAFEVALENVRPTVEVKCRRVGGCTYQVPVEVRPVRRNALAMRWIVEAAR----KRGDKCMALRLANELCDAAENK----GTAVKKREDVHRMAEANKKRLGRGIGCG-LGKTGGRGHKGQKCRCGG---G-VRRG-FEGGQMPL-----YRRLPKFGFKVILAGEVTTPVTVRGLRVTKGARAAIEAAGG------------------------MP----RCLKK----GLRTWCRRCTIFPNMIGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK--------ADNCGARRVMCIKVLG----GCHRRY--AGVGDIIKITIKEAIPRGKVKKGDVLKPVVVRTNKGVRRPDGCVIRFDGNACVLLNNN-SEQPIGTRIFGPVTRELRCEKFMKIICLA???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????--------------------------MAHIEKQA------GELGRIFCFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNNG----------TLQHPVKGVHTGCRVFMQPACEGTGIIAGGAMRAVLEVAGVHNVLAKAYG------STNPINVVRATIDGLQYLTKELAKACVCRIVIERP-AKCIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAG--VPAQINIAEV---RKPELDAKLVADCITCQLERRVM-FRRAMKRAVQNAMRL-GAKGIKVEVCGRLGGAEIARTEWYREGRVPLHTLRAD--IDYNTCEAHTTYGVIGVKVWIFKG--E-ILGG?????????????????????????????????????????????????????HTGALDPLATGMLPICLGEATKFCQYLLDCDKRYFRGDIEQIPCMYCALREARPITVYELLF--IGTYIRTIIDDLGEKLGCGAHVIYLRRLAVCKYPVERM--VTLPMDCPACDYPVVNLPLTCCVYFKNGNPVRTCG------NGKFI-MVDTE-----------IW-------LRLMCICCLY-H--------IDAVVLQQTGLTL----------------RQAQRFLCFPRKQLAVVGCRAHCWYGER---GRLFCETLATRGVTITCGLACLLEQGGALVCEFPLDVPVVEAALRCGCLVTFGLH--WLPDA---P-ENCFYCPDQEDVALP----FPELLANVGDEVTPVDVVAERAGQPVPEVVTQLL---EL---------ELAGWIAAVPGGYVRLRRACHVRRTNVFVALCKQVLKFGE---FTLKCGRKCFFNAGLFNTGRP--Y--CFNRKEAKGEGGN--LVG-SAL---QGRVMLVDDVITAGTAIRECMEIIQANG-MATVNQLVRKPRARK------------VAKCNVPALEAC------PQKRGVCTRVYTTTPKKPNCALRKCRVRL-TNGFEVTCYIGGEG--HNLQEHCVILIRG-------GRVRDLPGVRYHTVRGALDCCGVKDRKQARCKYGVKRPKATVCMRDML-----KAGVHFGHQTRYWNPKMKP--FIFGAR--NKVHIINLEKTVPMFNEALAELNKIACRKGKILFVGTKRAACEAVKDAALCCDQFFVNHRWLGGMLTNEKLENCLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNCDPDGVDFVIPGNDDAIRAVTLYLGAVAA-TV---REGR???????????????????????????????????????????????????????????????????????????????????????????????NYIFVTGGVVCCLGKGIAAACLAAILEARGLNVTIMKLDPYINVDPGTMCPIQHGEVFVTED--------G-----AETDLDLGHYERFIRTKMCRRNNFTTGRIYCDVLRKERRGDYLGATVQVIPHITNAIKERVDVVLVEIGGTVGDIECLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAACGEVKTKPTQHCVKELLCIGIQPDILICRCDRAVPANERAKIALFCNVPEKAVICLKDVDCIYKIPGLLKCQGLPDAYKCVIEALKHDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANCTEFVPDCKYPVRCEK----SDLGGTMRLGAQQCQLVDDCLVRQLY-NAPTIVERHRHRYEVNNM-LLKQIEDAG-----LRVA----GRC-GDDQLVEIIEV--PN--HPWFVACQFHPEFTCTPRDGHPLFAKFVECVDVAVNL-GIDARK-SDQNVRGATVLPHGTG-RCVRVAVFTQGANAEAAKAAGAELVGMEDLADQIKKGEM-------NFDVVIACPDAMRVVGQ-L-GQVLGPRGLMPVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVCICTTMG--------MARYLG-----PKLKLCRREGTDLFLKCGVRAIDTKCKIEQAPGQH----GA--RKPRLVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVCHKAIMVNGRVVNIACYQVCPNDVVCILRAPHVCEKACTAMEKCNTIVLKVAKDATKAEIKAAVQKLFEVEVEVVNTKKAYVTLKEGQ--NL-DFVGGAE?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????VEAIKRGTVIDHIPAQIG--------FKLLCLFKLT--ETDQR--ITIGLNLPCGEMG-R-KDLIKIENTFLCEDQVDQLALYAPQATVNRIDNYEVVGKCRPCLPERIDNV--LVCPNCNCICHA---EPVCCCFAVR-KRANDIALKCKYC???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????MQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAIC-GQKPLITKARKCVAGFKIRQGYPIGCKVTLRGERMWEFF-ERLITIAVPRIRDFRGLCAKCFDGRGNYCMGVREQIIFPEIDYDKVDRVRGRVCTLPCIVLRLLDKNCLQLCLNNLILVTGPTGCGKCTTLYAILCALNTP-GR-NILTVEDPVEYELEGIG-QTQVNTRVDM------SFARGLRAI--------LRQDPDVVMVGEIRDTETAQIAVQACLTGH-LVLCTLHTNCACGAVTRLR---DMGVECFL--LCCCLAGIIAQRLVRRLCPQCRQFTPVCPQQ--AQMFK----YHQLA-VTTIGT--PVGCPHC-H?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????AGRLAAEVLEMIEPYVKPGVCTGELDRICNDYIVNEQHAVCACLGYHGYPKCVCICINEVVCHGIP--DDAKLLKDGDIVNIDVTVIKDGFHGDTCKMLCRITQECLYLALRMVKPGINLREIGAAIQKFVEAEGFCVVREYCGHGIGR-GFHEEPQ-VLHGMTFTIEPMVN--AGKKEIRTMKDG--VKTKDRCLCAQYEHTIVVTDNGCEILTTM---------------------VG-------KVVP-----------------------PKRHILKNICLCFFPGAKIGVLGLNGAGKCTLLRIMAGIDKDIRLDEVYALYADPDADFDKLAAEQGR-LEEIIQAHDGHNLNV-QLERAADALRLPD-WDAKIANLCGGERRRVALCRLLLEKPDMLLLDEPTNHLDAECVAWLERFLHDF-------EGTVVAITHDRYFLDNVAGWILELDGIPWEGNYCCWLEQKDQRLAQEACQEAARRKCIEKELEWVRRLLIDCLCFCIPKGAIVGIIGPNGAGKCTLFRMICG--QEQPDC------GC-------VDQFRDCMD---NCKTVWEEVLCGGERGRLHLAKLLQVGGNMLLLDEPTNDLDIE----TLRALENALLEFPGCAMVICH--------D
Haloarcula_marismortui_strain_ATCC_43049                GAE-VAITGCNPLCT-----HDAERGVDDEEYYEAIEAVIG-----HKPTITVDDGMDLVAAIHGGAEETTTGVHRLRAMDDDGELDYPVFAVNDTPMKRLFDNVHGTGECCLACIAMTTNLCWAGKTVVVCGYGD-CGKGVAKKACGQNAD-VIVTEPRRALEAHMEGYDVK-PMAEADVFITTTGNRDVIVEEHFEAMQDGVLLANAGHFDVEVDLDALCDL-AVDTYEARNG-VQT--------YEMAD-GRRLNVLAEGRLVNLATPIALGHPVEVMDQCFGVQVHAVPDRLDKEVAEIKLDAEGVDFDCLTDTQAEYMDCWDIGGLDRELEQVREMIE-LPMRHPELFQQLGIEPPKGVLLHGPPGTGKTLMAKAVANEI-----DAYFTTICGPEIMCKYYGECEEQLREVFDEACENAP------AIVFIDEIDCIAPKRGETQGDVERRVVAQLLCLMDGLEERG------QVIVIGATNRVDDIDPALRRGGRFDREIEIGVPDKKGRKEILGADLATLTKECAMNALRGPPGTGKTLLAKA---VANEAQCNFICVKGP--ELLNKFVDEIDCIAGERGGGTTDCGVGERVVCQLLTELDG--IEDMENVVVVATTNRPDLIDDALLRPGRLDRGIAHVHACFNNTIITITDQTGAETLAKCCGGTVVKQNRDEACPYAAMQMAEVVAEKALDRGVEGVDVRVRGPGGN-LQTCPGPGAQATIRALARAGLEIGRIEDVTPTPHDGTRAP---KNCGGCCGRFGARYGRVCRRRVAEIECEMNEDHACPNCGE-DRVDRQGTGIWQCCYCDYKFTGGCYKPVDAGAVCFVCDGADIMRPGITEADDDICADDLVGKVVKCLHHVGDYCYIRDAWKNPGD-GQLAELQWQRQQEWRNEGAVERIERPTRLDKARCQGYKAKQGVIVARVCVRKGCARKRRHKAGRRCKRQGVTRITR-RKDIQRVAEERACRTFPNLRVLNCYCVGQDGRQKWHEVILIDPNHPAIQNDDDLCWICADDQADRVFRGLTGAGRRNRGLVVDIEHDPARCAPVAAVEFE---DGDRRLILAPEGVGVGDELGVCAEIAPGNTLPLAEIPEGVPVCNVECCPGDGGKFARACGVNALPCGEMKRLDPQCRATIGVVAGGGRTDKPFVKAGNKHHKMKARGTKWPNVRGVAMNAVDHPFGGGGRQH-PG--KPKCICR-NAPPGRKVGDIACKRNIAIAAHVDHGKTTLTDNLLAGAGMICD--DTAGEQLAMDTEEDEQERGITIDAANVCMTHEYEDQN----HLINLIDTPGHVDFGGDVTRAMRAVDGALVVVDAVEGAMPQTETVLRQALREGVKPTLFINKVDRLICELQEGPEEMQKRLLAVIQDVNDLILDMVCEHFPNPVDAQPMRVPRIWRGDAECQLADDMRLVNEDGEVVLMVTDIGVDPHAG-EIAAGRVFCGTLEKGQELYVCGT-AGKNRIQCVGIYMGGEREEVDRVPAGNIAAVTGLKDAIAGCTECIEHICEPVITKCVEAQNMDDLPKLIETLQQVAKEDPTIQVEINEDTGEHLICGQGELHLEVIGQ-RIERNQGIPINTGEPIVVYREAPQEDC-REVEGR------SPNNHNRFYICIEPGIQHLNETMELVIEGLEEALDDGPLACEPVQGCLIRLHDARLHEDAIHRGPAQVIPAVREAVHNCLIDACIKLLEPIQQVRIDVPNDHMGAACGEIQGRRGRVDDMYQEGDL-MVVEGVAPVDEMIG-FCCDIRCATEGRACWNTENAGFQVLADPFANALCALNNAECVGHLEQTVCPACNEIGCVLEVFYDRGYIDGFCFVD-DGE-FEVELKGA---INECG-------PVKPRYCAGADEFEK---WEK-RFLP--ARDYGTLVVTTCHGIMCHYEAREQGVGGQVIAYVYGDATVALVGFPCVGKCTLLNALTPGLI-EGAAGGRGGGKEVLC-VVRTADLR-------EHGYVNALTERIWEELGLIRIYMDKPGRGVDREEPFRF-----ARVGRDHELAD----EDMATLYDVPPEELIEALTETLADE-DDIEAPDWAEFTKTGVDRELPPEQE-D-FWTRRAACLLRKVAVDG-PVGVNALRCEYGTCKQGTTRYRVRPHQKTKGCGNIIRTALQQLEDAGYVETCEN--DGRRVTGDGRCLLDDTADARDCIMGRVACQVAGET-VAVVNAERAVITGREEQIVEKYE-KRVDIGN-----DNGYFYPKRPDGIFKRTIRGMLPH-KKQRGGEANPGPPLGPELGPTPVDVQAVVQEINDQTAAFD--GTEVP-VTVKY--DDDGCFEIEVGVPPTAELIKDEAGFET------GCGEPQE-DFVADLCVDQVKQIAEQKHPDLLCYDLTNAAKEVVGTCTCLGVTIEGENPREFKERIDAGKAGMTHVVLVNDEPNCPREGMEETVPVTVIETPPMRAVALRA-YEDTPYG--QRPLTEGGEHAMNDIFRAGEYADVAGVTKGKGTQGPVKRWGVQKRK-GKHARQGWRRR-IGNLGP-WNPCRVRCTVPQQGQTGYHQRTELNGFVNYGEVDGPYTLVKGCVPGPDKRLVRFRPAVRG-GIHPREAAEHMAFARGPGLGPCLRIVATAARAVAQRFDVPLVGVNHMVAHLEVGRHRC-----GFDCP-VCLNACGANAHILGYRN-GRYRV-LGETMDTGVGNAIDKFTRHIGWCHP----GGPKVEQHAR------DG---EYHELPYVVKG-----MDFCFCGIMCETIFAMLTEVCERAGGVGQNARLQRMLGEM-CEQREAEFYAPENRFLRDNAGMIAMLGAKMYAAGRVRLAGTCPEDLDDICADVREIANKTGVELCGPVPLPTKTLEVPCRKCPDGEGTATWEHWEMRVHKRLIDI-DADERALRQLMRIQV---PNDVCIEILCFGLMDPEEYREMCATKVITADTYDDDGF-PIDMGLMDPRL-GVIDPGLECKTCGKHCGCC---NGHFGHIELAAPVIHVGFAK----LIRRLLRGTCRECPF-------CRDWFEDIPD--EDR----PEWMILTVLPVPPVTARPCITLDNGQRCEDDLTHKLVDIIRINQRFMENREAGAPQLIIEDLWELLQYHVTTFMDNEICGT------PPARHR-SGRPLKTLCQRLKGKEGRFRGCLCGKRVNFCARTVICPDPTLCLNEVGVPDRVAKEMTQTMNVTERNLEEARRYVCNGPEAHP-------GANYVCRHLVDGDIIIFNRQPCLHRMCIMAHEVVVMPYKTFRLNTTVCPYNADFDGDEMNMHALQNEEARAEARVLMRV-QEQMLCPRFGENII--GAIQDHICGTYLLTGRCLFCELLPNGYDRGELECLPGRTVDETLEMKINPAVIMAECGARGCMLNLTQMAGCVGQQAVR--------GERINRGRTLCHFEENDL-SADAHGFVEACYRCGLGPKEFFFHAMGGREGLVDTAVRTCKCGYLQRRLINALCEMGK--VAAKIKVMPECPEVDLDDLE-DVAFGLVALTPTVIVPDDT-GGTEAVEEAFANVDDVVEGDNGCVTRRLWYP-DIDVCVDGDT----VTFQCHIENMFHGVTEGWEYGMEVFYCHFPMQVNVEGDE--VVIENFLGEKAPRRTTIH-G-DTDVEI---DG-EE-LTVCGPDIEAVGQTAADIGVDEAGKGPVLGCMFAAAVDCKDIRPERRERLAKEIDETDCLVGAACIIAKVARDTHVAELAA---EYGGRARRPLLVVE---DGGLVEFIDAEEGIGAGMIPYPEHNACPRITMGCGMIKQGLPCAN-YRIRPDTRQHLLHY-PQLCVKTQTTEQIG--YDDRPA--------AQNFVVAYEGFNIEDALVMNQGCVDRALARCHFFRTYEGEERRYPGGD-RFEIP--DDEVR--GARGEEAYTHLDD-DGLVNPETKVRFL--EEPDDMGGLC--PQKRRETCRCGECGVVDTVLCKVCVRDERGDKFACRHGQKGVVGHIAPQEDMPFTENPHALPCRMGHILEMIGG-------KGKETMYCGVTGEKIDAEIFVGDIFYQKLYHMVCNKLHARCRGPVQVLTRQPTEGRAREGGLRVGEMERDVLIGHGAAMALKERLLDECDREWINVCGQ--CGYAFKLLLDEMKALGIAPRIDAGLFIDAFDGFPGPYGRVNGEIV-APRGEG-GFGFDPIF-EH-------DG---TTFAEMCTEQKKTAVARATVREGEGRVRIDELVDP-ELAQLKMLEPDVEVCVEGGGVMGQADAARTAIARLRDAFMEFDRCLLVNDVRQCEPKK--WGGPGARARYQKCYRTQ----GQPVYGERRWDPHRCKLLYLGAAAGTTVCHVADFG---GPTYAVEFAPRVATRGQARVATLNGRLL--AAIKA-----RCEDVTADPDAVFDC-VRAELVFFNPVQELN--RDDIDDDATALCEQNDVDPFGTPIPFADAAVQG-TKH--LLCVTATDTAPLCGAHFECGVRCYGAVPR-NTEFHAEMGMRVLLCAMVRTAARYDIAAR--PILCHATKHYARTYLEFDHGAKVANDCID-ELGLYGCPGIGKTCAAHALALRDLCRQE-------GVEYECDALQELAEQNCGGLRGAVKDLDPCTERYITVTPIA--HTMGRHADKQFKKCEICIVERLINRLMGKKQLATCIVTEAFELVHERTDENPIQVLVCAVENCAPREETVRLKYGGICVPKAVDVAPQRRVDQALKFLAEGVYGGC-FKTTTTAAEALAQQLIGAANDD-VQ-TYAVNQKEEKERVAAAARRG-SRTHGGGCHKNRRGAGHRGGRGDAGR---DKHEFH----NHEPL-------G--KCGFKVLGAGQVRHELTLIADDFCEGAREKVEGAGGGHTLDELQ------EMELEEVAELLPARQRRCIVR----GIRTHLRDMPVVPEMVGLTFAVHDGQNFERVKVEPEMLGHYLGEFQLTRCCVEHGQAGIGATRCCKFVPLKADNTGARELKVICVHG-Y-SGTKNRHPKAGLGDKITVCVTKGTPE---MRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIVDEN-ED-PRGTELKGPIAREVAQR-FGCVACAARLAADVLDVGKNRVWF--NPERQGDIADAITREDVRELVDEGAIQAKDKKGNCRGRARERQKKRA-YGHQKGAGCRKGKAGARQ-NCKEDWECRIRAQRTKLRELRDEGT-LCCCQYRDLYDKAGGGEFDCVADLWEPRTRLGKQVVEGEIDCMQEALNCGLPLKECEVVDQLV-PDLGRRVKFRCVVAVGNRDGLIGYAEGRDDQVGGAIQKAIDIAKLNIIDVCRGCGCWECGCGRPHTVALRTEGKAGCVEVELQPAPRGLGLAGGETVRKVLELAGIEDIWTRCCG-----NTRTTVNFAKATFNALEFFAEELGRAGYGGMDVAKT-PMGTQIVLKAEKPGMVIGKGGKNIRKITTELEDRFN-LDDPQVDVQEV---DEPDLNARIVADRLANALERGWY-FRKAGHTTIDRIMEC-GALGAEIVLCGKVTG-ARCRVEKFNRGYVKHNGEPAEEIVDCGVGVAVMKLGTIGVRVKIIPP--NAELPDLKQNLTDGARKRLNTVKMCKPQVGEQIEQQVVALARCGRVQGQIDEDQMKELLHGGTLDPKVTGCLPVLLGDAARMAQVFDNAVKEYFETDIYQKPPRKCAVRQLRCRRIHCLDI--LGTYIRKLCHDIGLAAGTGAHMGDLRRTATGTFDDGCL--STMPAERALCHLPRVTIAPCAAREVAEGAPVYAPGVVCVTPDGAAVPAVQRPEGHVPFKRKL-TWTGGVLLLYFFLTNVKLFGG--SIMQLGIGPIVTACIVLQLLGGA--DLLGLNTQDDPRDQILYQGLQKQMFV-GGVLILFMDEVICKG-----VGCGIGLFIVAGVTVLIFAVVVYAECVRVEIPPVKLIYACVLPMIFAVF--WVETTDMGP-EATAKQIHNCGMQIPGFRQNVGVIEKVLERYIPQVTVIGGALVGLLAVMANML---GTIGGV-----SGTGLLLTVCITYKLYEEIAEEQLMEMHPLRDADAVKFGE---FELCHGGTCYVDKYVFETNPP--Y--VIARKQAKGTGNR--IEG-DLT--DGEEVIILEDIATTGQCAVDAAEALREAGGKYAARKLKKDRQKHRWCDTDYARRER-GLGKKCDPLEGA------PQGRGIVLEKVGIEAKQPNCAIRKVRVQLIKNGKQVTAFCPGDGAICFIDEHDEVTIAGIGGAKG-RAMGDLCGVNYKVEK--VNGVCLIELVRGN----AEKPVRLIPVEDYL-----GAGVHIGTQQK--TQDMER--FIHRVRT-DGLYVLDVCMTDERIRTAADFLCNY--EPEQILAACCRQYGRFPAEKFAEAIGARVRTGRFIPGTLTNPDYDGYIE--------PDIVVVTDPIGDAQAVKEAITVGIPVIAMCDCNNTTCNVDLVVPTNNKGRKALCVVYWLLAN-ET---LDRRKQAIVARADIGMGEGKLAAQVAHAWKGAGQKKVVLKATCECELFELADVAEREGLPHAVVRDAGHTQLDPGTVTALAVGPAEDELVDRVTGDLPLKFIFVTGGVMCGLGKGITAACTGRLLKNAGFDVTAVKIDPYLNVDAGTMNPFQHGEVYVLKD--------G-----GEVDLDLGNYERFLDIDMTFDHNVTTGKTYQHVIEKERCGDYLGRTVQIIPHITDDIKRRIDVCIIEVGGTVGDIEGMPYLEALRQFAHEEDEDDILFTHVTLVPYCKN-GEQKTKPTQHCVKELRCIGLQPDILVGRCCDKLDIDTKEKIGLFCDVPTEAVFCNPDVDDIYHVPLMVEEEGLEDAYMCVHEALKHDAIVVPGGFGARGTEGKIEAIRYARENDIPFLGLCLGFQMAVVEYARNVLDLDDAHCAELEEDTPHPVQYEI----EDMGGTMRLGAHETEINANTLAATLY-GGECCTERHRHRYEVNPE-YIDDLEAAG-----LKFC----G---RAGNRMEILELGPED--HPYFIGTQFHPEFRCRPTRACPPFRNFRETVDLAVNLRDLDLND-PCNRVDECVVLPAGTG-QETTIVVFAEGETALRAEEV-ADDVLDEDELEELGGDDDAAKDLADDTDFFIAEKGLMQDIGRYL-GTVLGPRGKMPVQLRCGERRTFHTRVGAEDMCAENIADNIDVILRRLHADLEKGPL--NIDTVYVKTTMGMAL-GCN-TKFYET--PNHPFQGERIADEANLIGRYGLK---NKEELWRAQCELRGY-RR--EARKLLKRYGIL---NEQDQLDDVLCLDVTDVLERRLQTVVYRKGYANTPEQARQFIVHGHIVLDDARVTRPGMTVETAVECCVIKHPHVTEKAMNDMDFQNKLQFAVDDRACKGEVADAVEEQYDVTVEQVNTKKAVVRLCEDD--DAQEVACRIGIYDLDGNTDGEVDL-PDVFETPVRCDLIGKAVRAAQANRKQDYGCDEYAGLRTPA------ECFGC--GRGQAHVP-K--QDG-------R-ARRVPQAVKGRCAHPPKTEKDRCLDLNDKERQLAVRCALAATADADLVADRGHEFDR-DEV--PVVVCDDFED-LVKTQEVVCLLEALDVHADIDRADET--KIKAGQGCARGRKYRRPACILFVNLAGADVATACEVNTEDLAPGGAPGRLTVFTECAARLECHGQRFEVLVDPDAALAIK--RDDFD-DDLEDVIAAEDVFEDACRGDRPPENMLEEVFDTTEPMAIIPEVIKRGEIQITADQRREMQEQKHKQLIQRITRNAVNPQMDDAPHPPERIECALEETDFRVDPMEPVEAQVDDALDALRPVIPIRFDEVTVAVQVPADYAGCAQAQIRQFG--DLEREEWQCDGCWVGVM-TFPAGLQNDFYDVVNEHTCGVCKIQNGTVIDHIAGGQA--------LNVLAILGIDG-TCGDC--VCVAMNMPCDRLG-H-KDVVKVEGRELCQNEVDVLCLIAPAATINIIRDYEVVEKGRVERPCVVEGV--LECPNHNCITTEN--EPVDCRFAVG-----DDGVRCEYCTNPRLCCLIADLKCAARCCGGAVWGDVAERLEKPRRTHA--EVNLGRIERYAQED-----ETVVVPGKVLGCGVLQKD-VTVAAVDFCGTAETKIDQV-GEA--VCLEQAIE--NNPEGCHVRVPVRCFTCGNVVGEHWEEFKART--REAEEPEDP-----EKVLDELGVERHCCRRMLVCHLDEGCYVMI------EDTPCKINCYCTAKPGKHGCAKARIDAKGVFDGKKRCLCQPVDAKVWVPIVNRKQGQVQVMDLDTYDTDDEIEYLQY-EEQRKIKYLIHADITAAGVVDV-----VGAFGQTEGLLGDEL----DLRDLQDCKKVGRIA---AALETIEQ--------VGPCRAEIEVCEIEDVRCAKRREVVERAVADCDAIVVVEGRCD------VMQLLK--YGIKNAVAGTD--VPDAIADLTAGRTV--TCFLDGD--------RGGDL------ILKELAQV-GDVD---YVAVTPCDK-SVEDLCRCE----VMCALDVAAQR--GVDVVVAAGHG-EY-VKQPMREPRIEKVVVHMGIGHG---GRDLANAEDILGEIT-GQMPVRTKAKRTVGEFDIREGDPIGAKVTLRDEMAEEFL-QTALP--LA---E---LATCQFDDTGNFCFGVEEHTEFPCQEYDPCIGIYGRIAIARPPEITAVRP-IVKTELDDYVLICGCPGAGKCTFAQAVGEFLVDA-DY-AVKTMEKPRDLQVGP---NITQYTELGG------SMEKTADCL--------LMVRPDYTIYDEVRKTDDFEVFADMRLAGV-GMVGVVHATRAIDALQRLIGRVELGLIPQI---VDTVVYIEAGEVDTVYDVTTEVKVPQGLME--EDLAR-------PV-IMVKDF--ETNRPEF-EGRCPRKRTGG-RRRPNHK-KKKHELGKDTVETQVG--EQ--RLKTVDCRGNTQKVRAVKTDVACIAD--GAETIEATIENVVENPCNPNYARRNIITKGAILETCEGQARVTCRPGQHGQVNAVLAGEILAQVRDEAAERVEVGVCHLEVAQWAEDKIR-ELGGKPA------FP--VNICIDEEAAHATPERDDDATFGE-EMVNLDIGVHVDGWLADTAVTLAKAPEEALDAALDVAGPGVDVGQIGAAVEEVIEGYGYNPVVNLTGHGLGHWEQHTCPN-IPNGDVVAIEPFAT--DGRGKVQEGADEEILKEQDGAYVCQKEHTVIITEDGCEVTTCQ-PDRCN-YECMNYCPICEEICLGECCGICVNKCPFDAIEIINLPQELTDE-PVHRYGENAFALYGLPC-PAEGQVTGILGPNGIGKTTAVRILADEMQPNKPQ-----YVDR---IPNQF--DGK-AIELLDQTDER---G-ALDYLVEQTGIEPVVDNHIDDLCGGELQRVALVATLARDADFYFLDEITPYLDIGQRMTAARLIRELAE-E--EDRCMLVVEHDLAILDLLADNINVAYGTP--GAFGVITPPKCTKKGINEYLCG----YLENENMRIRFCLDVEAGT-IRECEVLGVVGPNGIGKCTFAKMLAG--RLEPTA------GY-------KPQYI-EID---QPMRVDAFLLCGGERQRVAIAACLCKDADLYLLDEPCAHLDVEQRVMATCAIRRYAENHDATAMVIDH--------D
Halobacterium_salinarium_R1                             GAE-IAITGCNPLCT-----HDAERGAEGEAYYDAIDAVLA-----HEPTVTVDDGGDLVFRVHGGTEETTTGVHRLRAMDDDDALEYPVFAVNDTPMKRLFDNVHGTGECALANIAMTTNLCWAGKDVVVAGYGD-CGRGVAKKAAGQNAN-VIVTEPRRALEAHMEGYDVM-PMAEADVFLTTTGNKNVITRAHFERMDDGVVLANAGHFDVEVNLDHLCEL-AVCEREAREG-VRE--------YELAD-GRRLNVLAEGRLVNLACPIGLGHPVGVMDQCFGVQVHNVPDELDIEIAEIKLAAEGVEYDALTDDQAEYMDCWDIGGLDDELEQVREMIE-LPMRHPELFGTLGIEPPKGVLLHGPPGTGKTLIAKAVANEI-----DAHFQTICGPEIMCKYYGECEEQLRDVFEEAEENAP------AIVFIDELDCIAPKREDVCGDVERRVVAQLLCLMDGLEERG------QLTVIGTTNRVDAVDPALRRPGRFDREIEIGVPDHDGREKILGADLENLVKECAMHALRGPPGTGKTLLAKA---VANEANCNFICIKGP--ELFNKYVDEIDAIACERGQGVGDCNVGERVVCQLLTELDG--LEELEDIVVIATTNRPDLIDDALLRPGRLDRGIAHVHACFNNTIMTVTDQTGAETLAKCCGGCVVKQNRDEACPYAAMQMAEQLAEEVLDQGIEKVHVRVRGPGGN-LQRCPGPGAQAAIRALARAGLEIGRIEDVTPIPHDGTRPP---KNCGGCAGRFGARYGRVCRRRVCDIEGTMNEDHACPDCGC-EAVCREGTGIWQCGKCGYKYAGGAYQPVDAGAVCFVCDGADVMRPGITAACPEITAGDLVGKVVCCLHHVGDYCHIKEAWEDPDD-GKLAELQWQRKQDWRKEGAIERVDRPTRLDKARELGYKAKQGVVVVRVCVRKGTARKCRFKAGRRTKRQGVNRIGR-AKNLQRIAEERACRKYVNLRTLNCYWVGEDGCQKWFEAILLDPEHGAIQNDDDLNWICDDCHKNRVFRGKTCAGRRARGLVIDVEHDPARCAPVARVAFE---DDDQRLVLACEGVGVGDTIGICATIEEGNTLPLAEIPEGVPVCNVECHPGDGGKFARAGGVNALPCGETKRLCPDCRATIGVVAGGGRTEKPFVKAGNKHHKMKARGTKWPRVRGVAMNAVDHPFGGGGRQH-PG--RPKCVCR-DAAPGRKVGDIACKRNIAIAAHVDHGKTTLTDNLLAGAGMICE--DTAGQQLAMDTEEDEQERGITIDAANVCMTHEYEGDD----HLINLIDTPGHVDFGGDVTRAMRAVDGALVVVDAVEGAMPQTETVVRQALREGVKPTLFINKVDRLICELQEGPEEMQERLLCVIGDVNELILDMVAEHFPNPIDAQPRRIPTVWRGDADCEIAECMRLVDEDGEVVLMVTDIGVDPHAG-EIAAGRVFCGTLEKGQELYVCGT-AGKNRVQCVGIYMGGEREEVDEVPAGNIAAVTGLKDAIAGCTECIDHICEPVITKCIEAQNMDDLPKLIETLRQVCKEDPTICIEINEDTGEHLICGQGELHLEVQTQ-RIERNQGIPVTTGEPIVVYRETPTCDC-QEVEGV------SPNRHNKFYITVEQGIQHLNETMELVVDGLTDCLEDGPLAAEPVEGALIRLHDARLHEDAIHRGPAQVIPATRDAVHRALIDADIRLLEPIQDVRIDVPCEHMGAACGEVQGRRGRVDDMYQEGDL-MVVEGIAPVDEMIG-FCCDIRCATEGRACWNTENAGFRVMADPLCDALCGIDNAECVGHLTHTVAPACNMVGCVLEVFYDRGYIDGFEFVD-NGR-FEVELKGA---INECG-------PVNPRYCVGADGFEQ---WEK-RYLP--ARDYGCLVVTTCHGIMCHYEAREAGIGGQVIAYVYGDATVALVGFPCVGKCCLINAMTPGLI-EGAAGGRGGGKEILC-VIRGADLR-------ERGFINALKERMWRALGLIRIYMDKPGRGVDREEPFRF-----ARVGRDHVLED----EDMATLYDAPVDELIDELAADLETR---LDEPDWANYAKTGAGRELPPEQC-D-FWATRAACLLRKVAIDG-PIGVKRLCEAYGCTTCGCNRYVVAPCTTTAGCRNIVRTILQQLEAEGLVEQQHD--HGRVVTGDGRCLLDETADARDCIMGRVACNVAGDR-VAVVNAEQAVITGTEDDVFCTYR-TRANLGC-----DRGPYYPKRPDGIFKRAIRGMLPY-KQDDGGQADPGPPLGPELGPTPVDVQAVVQEINDQTEAFD--GTEVP-VTIEY--EDDGCFCIEVGVPPTAALVKDEAGFDT------GCGEPQE-NFVADLCIEQLKTIAEQKKPDLLAYDARNAAKEVAGTCACLGVTIEGEDARTFNERVDDGKAGMTHVVLVDDKANAPTEGMETTVPVTVVETPPMRAAAVRL-YEDTPYG--KKPLTEGGVHAFGDVFRAGEFTDAAGITKGKGTQGPVKRWGVQKRK-GKHARQGWRRR-IGNLGP-WNPCRVRCTVPQQGQTGYHQRTELNGFPNYGEVDGPYTLVKGCVPGPEQRLVRFRPAVRG-GIHPREAAEHMAFCRGPGLGPCLRIVGCAARALAQALDVPLVGVNHMVAHLEIGRHQC-----GFQQP-VCLNACGANAHVLAYRN-GRYRV-LGETMDTGVGNAIDKFTRHVGWQHP----GGPKVETHAR------DG---EYTALPYVVKG-----MDFCFCGIMCETMFAMLTEVAERAGGVGQNDRLRGMLEAM-CAARGACFHAPEPRFLRDNAGMIAVLGAKMAAAGRVRLAGVDPDDLDNICGEVQEIADKTGVKVCGPVPLPTKTLEVPCRKCPDGEGTATWEHWEMRVHKRLIDI-DADERALRQLMRIQV---PNDVNIEIICFGLMDPEEYRDMCATKVITADTYDDDGF-PIDMGLMDPRL-GVIDPGLECKTCGQRCGGC---NGHFGHIELAAPVIHVGFCK----LIRRLLRGTCRECPH-------CRDWFEDIPG--EDR----PEWMILTVLPVPPVTARPCITLDNGQRCEDDLTHKLVDIIRINQRFMENREAGAPQLIIEDLWELLQYHVTTFMDNEICGT------PPARHR-SGRPLKTLCQRLKGKEGRFRGCLCGKRVNFCARTVICPDPTLCLNEVGVPDRVATEMTQTMVVNEQNLERARRYVRNGPEGHP-------GANYVQRHLIDGDIIIFNRQPCLHRMCIMAHEVVVMPYKTFRLNTVVCPYNADFDGDEMNMHALQNEEARAEARVLMRV-QEQILCPRFGENII--GAIQDHICGTYLLTGHQIFCELLPNGYENGDLECLPGRTVDETLEMKINPAVVMANCGARGCMLNLTQMAGCVGQQAVR--------GERINRGRTLCHFAPNDL-SCEAHGFVENCYTCGLTPKEFFFHAMGGREGLVDTAVRTCKCGYLQRRLINALCEMCK--VAAVLKVMPDCPDIDLDGLE-EVAFGLTALLTTVIVPDDC-GGTEAVEDAFGAVDDVVEGPEGCVTRRLWYP-DVDVCVEDDA----VTFECHVANMFHGVCEGWEYKLEVHYCHFPMQVDVEGEE--VVIQNFLGEKAARRTQIR-G-DTDVVV---DD-EE-VTLCGPCIEDVGQTAADIGVDEAGKGPVLGCMFAAAVDCKRLCADRRAELDDRVDDEYDLVAAACIVAKVARDAHVDALAA---AFDGRARRPLLVVE---NGGKVEFIDAEEGIGAGMIPYPEHNACPRITMGAGMMKQGLPAAN-YRIRPDTRQHLLHY-PQKAVNTQTTEQIG--YDDRPA--------GQNFVVAYEGFNIEDALVMNKGCVERALCRCHFFRTYEGEERRYPGGD-RFEIP--GDDVR--GARGEDAYTHLDD-DGLVNPETKVRFL--EEPEDMGGLC--PQKRRETCRCGEDGVVDTVLAKVCVRDERGDKFACRHGQKGVVGHLAPQEDMPFTQNPHALPCRMGHVLEMLGG-------KGKEVMYCGVCGEKIEAEIFVGTIFYHKLYHMVCNKLHARCKGPVQVLTRQPTEGRAREGGLRVGEMERDTVIGHGAAMVLKERLLDCCDREEIHVCGN--CGYAFKLLLDEMKALGIAPRLDAGLFVRGLCGFPGPYGAVQGTMV-APRGDG-GFGYDPIF-EH-------DG---TTFAEMPTDRKKTAVARATVCDGEGRVRINELVEP-EMARLKMLEPDIDIDVAGGGFAGQADAVRTAIARLRDAFREFDRCLLVNDVRQRECKK--WGGPGARARYQKCYRTR----GEPAYGERRWDAHRCKLLYLGAANGTTVCHVADFA---GPTYAVEFAPRVATRGQADVALCNGRLV--AALKA-----RCEDVTADPAAVFED-LLGRLVFFNATQELN--RDDVDADAVELATCNDIDPFGCPMPFADAAFAN-ARN--LVCVTATDTAPLCGAHFECGVRKYCATPR-NTNYHAEMGLRILLGALARTAARYDVGVT--PILCHVCDHYVRTYLELDHRATDANAAVE-QVGVHGCPGIGKTCAAHALALRDVCRRE-------DVTYEEDALAAIAEQNAGDLRCAVNDLDPCTRRYLAVTPVA--HTMGRHAQKQFKKCEICIVERLANRLMGKKQQALKIVRDAFDIVHERTDENPIQVLVCAVENAAPREETVRLKYGGICVPQAVDTAPQRRVDQALKFLADGAHCAC-FKTPTDAAEALANQLAGAADYN-VQ-TYAIGQKKEKERVAAAARRG-SRTHGGGTHKNRRGAGNRGGRGRAGR---KKHEQH----NYEDV-------G--KCGFKVLGGGQLYEQLEVTADAFCDAAVELIEGEGGGHDLDELQ------EMCLEDVAELLPARQRRTITR----GIRTHLRDMPVLPEFVGLTFAVYTGQEFERVEVQPEMIGHYLGEFQLTRCCVEHGQAGIGATRCCKFVPLKADNTGARELKITCVMG-Y-QGRKNRHPKAGLGDTITVCVTKGTPE---MRRQVLEAVVVRQRKPIRRPDGTRVKFEDNAAVIIDDL-GE-PRGTEIKGPICREVAER-YGTIACTARLAADVLDVGENRVWF--DPDAQCEIADAITREDIRELVADGTIDAEDTQGNCRGRARERDAKEC-YGHKKGAGCRKGKAGARQ-NEKREYVAGIRAQRQQLRELRDDGT-LCPAQYREMYNMANGGEFDCVRRLWQPKTRLGGLVQDGEVEDMCEALDTGLPLKEPEIVDQLL-PGLGRRVKFRCVVAIGNRDGYVGYAEGRDDQVGGAIQKAIEVAKLNIIDVCRGCGCWECGCGRPHTVALKCTGKAGCVDVELMPAPRGLGLAGGETVQHVLELAGIDDVWTRCCG-----KTRTTVNFAKATFNALEFFAEELARAGYGGMELAPT-PMGMQIVLKAEKPGMVIGKGGKNIRKITTQLEERFD-LEDPQIDVQEV---EEPDLNAQIVADRLANALERGWY-FRKAGHTTIDRIMEC-GALGAEIVLCGKVTG-NRGRVEKFNRGYIKHNGEPAEEIVDHGKGVAVMKLGTIGVNVKIIPP--NAELPDLKQNLTDGARKRLNTIRMCKPEFAEQAEQQVLALAQCGRVQGRIDEDQMKEILHAGTLDPKVTGCLPVLTGTATRIAPALLEGFKEYFTGEIYQKPPKKCAVRRLRTRTVYDLDV--LGTYIRKLCHDIGRALGTNAHMGHLRRCATTPFDDTDL--VTLPAERALTHLPRLTIADCAAHEVATGAPVYAPGVACYTAGGTAVPAVERPEGHVPFRRKM-YWTGGVLVLYFFLTNVPLWGG--TVLQLGIGPIVTACIVLQLLGGA--NLLGLDTDNDPRDQAIYQGLQKQIAA-GGILLLFMDEVICKG-----VGCGIGLFIVAGVTLFIYVVVVYAECVRVEIPPVKLIYACVLPMIFAIF--WVETADMGP-DATARQIQNCGMQIPGFRKNQGVIEKVMERYIPQVTVIGGALVGLLAVMANML---GTIGNV-----SGTGLLLTICITYKLYEEIAEEQMMEMHPLRAADAVQFGE---FELCHGGTCYVDKYLFETDPP--Y--VIARKQAKGTANR--IEG-RLD--DGEEVVVVEDIATTGQCAVDAVDALRDAGGKYAARKLKKDRQQRRWCDCEYARRER-GLGKKCDPLEGA------PQGRGIVLEKVGIEAKQPNCAIRKVRVQLIKNGKQVTAFCPGDGAICFIDEHDEVTIAGIGGAKG-RAMGDLCGVNYKVEK--VNGVCLIELVRGN----AEKPVRLIPVEDYL-----GAGVHIGTQQK--TNDMDR--FIHRVRT-DGLYVLDVCRTDDRVRTAADFLANY--DPEQILVTCCRQYGRFPAEKFAEAVGARARTGRFIPGTLTNPDYDGYIE--------PDVLVVTDPIGDCQAVKEAITVGIPVIAMCDCNNQTGNVDLVVPTNNKGRRALCVVYWLLAN-ET---LDRRKQVIAARTDIGMGQGKLAAQVAHAWKDEGQTKVVVKVGCERELYERCEEAKRAGLPTGLICDAGRTQLEPGTPTALAIGPAPDADVDQITGDLCLKFVFVTGGVMCGLGKGITAACLGRLLCNAGFDVTAVKIDPYLNVDAGTMNPYQHGEVYVLDD--------G-----GEVDLDLGNYERFLDEDMTCDHNVTTGKVYQDVIERERCGDYLGKTVQIIPHVTDDIKRRVDVCLVEVGGTVGDIEGMPFLEALRQFCHEQDDEDILFTHVTLVPYCKN-GEQKTKPTQHCVKELRCIGLQPDILVGRCEDRLDPDVREKIALFCDVPMDAVFCNPDVEDIYHVPLTVEEEGLEDAYMCIHEALKHDGIVVAGGFGCRGTAGKIDAIQHAREHDVPFLGLCLGFQLAVVEYARNVLGMTGAHCAEIDEDTEYPVQYDL----EDLGGTMRLGAHETAIEPGTLAHDLY-GATCCTERHRHRYEVNPE-YIDDLTADG-----LTFC----G---EAGNRMEIVEH--DD--HPFFFGTQFHPEYRCRPTRACPPFRNFRETVDLAVNLRDLDLND-PCQRVDEGVVLPCGTG-QETQIVVFADGETAVRADDV-ADDVLDEDDLCDLADDTDAAKDLADETDFFVAEAPMMQDIAGAL-GQVLGPRGKMPVQIRCRDRRTFHTRVGAEDMCAEDIACNIDVIMRRLHANLEKGPL--NVDCVYVKTTMGMALPGEN-TKFYET--PNHPYQGERIAEECDLLCRYGLK---NKEELWRAQCELRDY-RR--EARRLLQRIGIL---SEEERLDDVLCLEVTDVLERRLQTVVYREGLANTMGQARQFVCHGHVTVDGCRVTEPCYTVPVCEENTLIDYPLVTEKAMDEMDFQNKLQFIVDIDAAKPEIRDVVECEYDVTVVDVNTKKATVKLCAED--DAQDVACRIGVRDLDGDDAGTLDL-PRVFEEPVRPDLVKRAVLAAQANRTQEYGADEYAGLRTTA------ECQGC--GRGMAHVP-K--ANGQ--------GARVPQTVGGRKAHPPKAEKDHGLDVNDKERKAAVRAAVAATTDCELVADRGHNFDDDVEF--PLVVCDDFED-LVKTQDVVCLLEALGVHADIERADEGR-TVRAGQGTLRGRKYQEPTCILFVNLAGVDVATGREVNAEDLAPGAEPGRLTVWTECAARLETHGERFEVLVDPDAALEMR--RDEFD-GELTDVIAARDVFENACRGDRPAECDLETVFGTTEPLEIIPEVIGQGEIQITADQREAMQQRKKRCLINTICRNAINPQMDGAPHPPDRIECALDEAGFTVDPMTPADEQVDDALEALRPVIPIRFEEMTVAVQLPADYAGCGQAKLREFG--ELEREEWQADGCWVGVI-TFPAGMQDEFYGRVNEVCEGVCKIQAGTVIDHIPAGQA--------LQVLQILGTNGACDDQ---ITVGMNVTCERHH-R-KDIVKIEGRELCQDEVDVLCLIAPDATINIVRDYEVDEKRRVDRPDVVAGV--LCCPNPNCITAND--EPVRCGFDVL-----DDGMRCQYCTCPRLCCLIAELKCVARDCGADVWHDVADRLEKPRCTHA--EVNLCRIERYACED-----ETVIVPGKVLGCGALRKC-VTVAAVDFCCCAATKIEHADGEA--VHLEQAVE--QNPDGTDVRVPVRCFCCGTVVGEHWEAFKARAETHDGDE--DP-----ADVLDDLGVDRHCCRRMLIAHLQEGNYVMM------EDAACQINAYCTAKPGKHGCAKARIEAEGVFDGKKRCLCQPVDAKIWVPIVNRKQGQIQVMDLETYETDENIEYLEF-EGQRKIKYLIHADFVVDGVVDV-----VGAFGQTEGLLGDDL----AIPDLQDCAKLGRIA---AALEAVER--------IGPCRADVEVDRIEDVRAAKRREVVDRAVDCCDAVVIVEGRAD------VVTLLK--YGIKNAVAGTN--IPDAIAALCREKTA--TAFLDGD--------RGGDM------ILRELGQV-GCLD---FVARAPMGE-CVEDLCRRT----VDCALDVAAQR--GVACLIGADTD-EF-VKQPMREPRIEKVVVHMGVGQG---GVELQNAETILEAIT-GQQTVRTKAKCPEPEFGLRQGDPIGAKVTLRDDTAVDFL-ERALP--AA---D---LDRRQFDNTGNVCFGIEEHTDFPCQEYDPNIGIYGRIAICEPPEITAVRP-IVKTTMDDYVLIAGAPGAGKCTFAQAVAEFLADA-GN-VVKTMEKPRDLQLDE---EVTQYTALCG------SMEKTADCL--------LMVRPDYTIYDEVRKTDDFEVFCDMRLAGV-GMVGVVHATRPIDALQRLVGRVELGMIPQI---VDTVVYIEAGNVETVYDVTTEVKVPEGLME--EDLAR-------PV-IQVRDF--ETNVPAY-EGRCKRCKTGA-RLRPRCK-KCKCELGREPTETTVG--EP--RFRTVDVRGDAEKVRVLCTNVVNVAT--DCGAERATIEDVCANDANPNYARRNIITKGAIIETDAGTARVTCRPGQDGQVNATRAGDILTTVLCEAADRVTVGATHLEVACFAEERIR-ELGGEPA------FP--VNICVNEEACHAAPGADDDTEFGE-DMVCLDVGVHVDGHIADAATTLVEAAEECLAAAIDMVEPGVQTGALGAEIQDVVEAYGYNPVVNLTGHGMDVFDAHTGPT-VPNGDVVAIEPFVT--TGTGKVTEGAATEILKEADGELVGQDEHTLIVTEDGCEVVTCQ-PDRCN-YECCNYCPICEEICLGECCGICVEKCPFDAIEIINLPQELDDQ-PTHRYGENCFCLYGLPV-PECGKVTGLLGPNGIGKCTAVDLLAGEVTPNKPQ-----YVDE---IPAQF--DGN-TRQLLEATDER---G-VLDDLVDRLCIRPVMDQAIDCLCGGELQRVALAATLARDADFYFVDELTPYLDIGQRVTAARLVRELAE-D--ADKAVLVVEHDLAVLDMLADCIHVAYGEP--SVYGVVTPPKCVRNGINEYLRG----YLENENMRVRFTLCVEGGD-INRNEVLGVVGPNGIGKCTFAQLLAG--GLEPCCVGGEAGAY-------KPQYV-EAD---QQMRVDAFLLCGGERQRVAIAATLCKDADLYLLDEPCAHLDVEQRVLATRAIRRFAENNECTVMVIDH--------D
Halorubrum_lacusprofundi_ATCC_49239                     GAE-VAITGCNPLCT-----HDAVRGVDDEEYYDAMHACIA-----HDPTITVDDGMDMVKLVHGGAEETTTGVHRLRAMDADGELHYPVFAVNDTPMKQLFDNVHGTGECCLATIAMTTNLCWAGKNVVVGGYGQ-CGKGVAMKACGQNAN-VIVCEPRKALEAHMEGYEVL-PMVEADVFITTTGNRDVITREDFEEMQDGVLLANAGHFDVEVNLDDLDDL-AVDRFEARDG-VEG--------FEMAD-GRVLNVLAEGRLVNLAAPICLGHPVEVMDQCFGVQVHDVPDDLDREVAEIKLDAEGVEHDALTDEQREYMGCWDIGGLDNELEQVREMIE-LPMRHPELFKRLGIDPPKGVLLHGPPGTGKTLIAKAVANEI-----DANFHTICGPEIMCKYYGECEEKLREVFEEACEEAP------AIIFMDELDCIAPKREEAGGDVERRVVAQLLCLMDGLEERG------EVVVIGATNRVDAIDPALRRGGRFDREIEVGVPDRDGRKEILGADLECLAKECAMHALRGPPGTGKTLLAKA---VANECECNFICIKGP--ELLNKFVDEIDCIATERGKNCGDCGVGERVVCQLLTELDG--LECLEDVVVIATTNRPDLIDCALLRPGRLDRGIAHVYACFNNTLITVTDETGAETIAKCCGGTVVKQNRDEACPYAAMQMAEVVAERVKDAGLEGVHVRVRGPGGN-LNKCTGPGAQATIRALCRAGVEIGRIEDVTPIPHDGTKAP---KNKRGCAGRFGARYGRVCRKRVQDIEEEMQN----ATVDG-DDVKRVGTGIWVNEETGETFTGGAYRPVDAGAICFVCGGADVMRPGIVEADCAIREGDLVGKVVECIHHVGDYCHIKEAWRCPKE-GKLAELQWQRKQEWRDEGAIERIERPTRLDKARELGYKAKQGVVVARVCVRKGGCRKQRHKAGRRCKRQGVNRLCR-RKCIQRICEERACRKYRNLRVLNCYWVGEDGCQKWHEVILVDPNHPAIENDGDLGWIACDDHKGRAFRGLTCAGTKGRGQIVGIEHDPARCAPLAEIEFE---DDDRRLVLAPEGVRVGDTIGVCAEIKPGNTLPLAEIPEGVPVCNVECNRGDGGKFARACGVCALPCGEVKRLDPQCRATIGVVAGGGRTEKPFVKAGNKYHKMKARGTKYPRVRGVAMNAVDHPFGGGGRQH-PG--QPKCVCR-DAPPGRKVGDIACKRNIAIAAHVDHGKTTLCDNLLAGAGMICQ--DTAGEQLAMDTKEDEQERGITIDAANVCMTHEYEDTN----HLINLIDTPGHVDFGGDVTRAMRAVDGALVVVDAVEGAMPQTETVLRQALREGVKPALFINKVDRLICELQEGPQEMQERLMCVIADVNELILDMVCEHFPNPVDAQPRRVPRIWRGDAECELADTMRMVNEDGEVVFMVTDICMDPHAG-EIATGRVFCGTLEKGQELYVCGT-AGKNRIQCVGLFMGCEREEVDRVPAGNIACVTGLRDAIAGCTECIEHICEPVITKCVEAQNMDDLPKLIETLQQVAKEDPTIQIEINEDTGEHLICGQGELHLEVITQ-RIRDNQGIPVITGEPIVVFREQPQEAC-REVEGQ------SPNRHNKFYLTVEPGIQHLNETMELVLEGLQEALDDGPLAAEPVQGCLFRLHDAKLHEDTIHRGPAQVIPAVRNAVHRCLIDGEVRLLEPIQDVRIDVPCEHMGAACGEIQGRRGRVDDMYQEGDL-MVVEGIAPVEEMIG-FCCDIRCATEGRACWNTENAGFRVLVDPFTNALAGMDNAECVGHLCYTVEPACNIIGCVLEVLYDRGYVDGFEYVD-DGK-FEVELKGA---INECG-------AVKPRYCAGADEFEK---WEK-RYLP--ARDYGTLIVTTCHGVMCHYEAREEGIGGQVIAYVYGDATVALVGFPCVGKCTLINALTPGLI-EGAAGGRGGGKEVLC-VVRTADLR-------EYGYVNALRERLWEELGLIRIYMDKPGRGVDYEEPFKF-----ARVGKGHELAD----EDMVTIYDVPADALIEEVAARLEDR---IDEPDWVEFAKCGAGKELPPEQE-D-FWYVRCACLLRKVAQNE-PIGIERLATEYGCKKRGCNRYCVRPGEHEGGCRKLIRACLQALEEDGLVTTAAG--EGRRICDDGEAFLCEVADARDCILGRVCCKVAGET-VAVVNAERAVITGNEEATMETYH-TRAELGC-----DCGPYYPKRPDRIFKRAIRGMLPY-KTEDGGQATPGPPLGPELGPTPVDVQDVVAQINDETAAFD--GMEVP-VTVEY--DDDGCFTIEVGVPPTAELIKDEAGFET------GCGEPQV-DFVADMCIEQVKKVAEQKCTDLLAYDVKNAAKEVGGTCACLGVTIEGEDARTFDDRVDAGKAGMTHVVMVNDEANCPREGMETCVPVTVVETPPMYAVALRA-YEQTPYG--KKPVEEGGAHEFGDVFRAGQYTDVCGITKGKGTQGPVKRWGVQKRK-GKHARQGWRRR-IGNLGP-WNPCRVRCTVPQQGQTGYHQRTELNGFVNYGEVDGEYALIKGCLPGPDKRLIRFRPAIRG-GIHPREAAEHMAFCRGPGLGPCLRIVGTAARCLAGTLDVPLVGVNHMVAHLEIGRHQC-----GFENP-VCLNTCGANAHLLGYHD-GRYRV-LGETMDAGVGNAIDKFTRHVGWDHP----GGPKVEAAARRYAEGNDG-PEDLLDLPYVVKG-----MDFCFCGICCEHVFAMLTEVCERAGGVAQNDRLREMLACM-CAARGARFHAPDCRFLRDNAGMIAVLGAKMAQAGRVRLAGTCPEDLDDICADVREIADCTGVALCGPIPLPTKTLEIPCRKCPDGEGTATWEHWEMRVHKRLIDI-DADERALRQLMRVQV---PNDVCIEIIDFGLMDPETYRDMCATKVITADTYNDDGY-PIDMGLMDPRL-GVIDPGLECRTCGCHCGCC---NGHFGHIELAAPVIHVGFTK----LIRRLLRCTCRECPF-------CRDWFEDIPD--EDR----PEWMILTVLPVPPVTTRPCITLDNGQRCEDDLTHKLVDIIRINQRFMENREAGAPQLIIEDLWELLQYHVTTFVDNEICGT------PPARHR-SGRPLKTLCQRLKGKEGRFRGCLCGKRVNFCARTVICPDPTLCLNEVGVPDRVAMEMTQTLNVTERNVEEARQYVRNGPEAHP-------GANYVNRHLVDGDIVIFNRQPCLHRMCIMAHEVVVMPYKTFRLNTVVCPYNADFDGDEMNMHALQNEEARAEARVLMRV-QEQILCPRFGGNII--GAIQDHICGTYLLTGRTLFCELLPNGYEAGELECLPGRGVDETLEMKINPAVVMARCGARGCMLNLTQMAGCVGQQAVR--------GERINRGRTLCHYRPNDL-SCEAHGFVENCYRCGLTPEEFFFHAMGGREGLVDTAVRTCKCGYLQRRLINALCEMGD--VAAKIKVMPNCPDIDLDDLD-DVAFGLVALLPTVIVPDGA-GGTEAVEEAFNEVDGVVEGPNGCVTRRLWYP-DVEVTVEDGV----VTFECHVANMIHGVTDGWEYTMEVYYAHFPMQVTVEGDE--VVIENFLGERAQRRTPIR-G-DTDVQI---DG-ET-VTLCGCDKEAVGQTAADIGVDEAGKGPVLGPMVAAAVDCKRIAPCRRECIDAEIDEDDPMVGAACVVAKVARDERMADIDADYPAYDGRARRPLIVVE---NGGYVEFIDAEEGIGAGMIPYPEHNACPRITMGAGMMKQGLPCAN-YRIRPDTRQHLLHY-PQLAVKTQTCDQIC--FDKRPA--------AQNFVVAYEGFNIEDALVMNQGCVDRALTRCHFFRTYEGEERRYPGGD-RFEIP--DQDVR--GARGEDAYTHLDE-DGLVNPETKVRFL--EEPDDMGGLC--PQKRRETCRCGECGVVDTVLCKVKVRDQRGDKFACRHGQKGVVGHLAPQEDMPFTENPHALPCRMGHVLEMLGG-------KGKEVMYCGVTGEKIEAEIFVGTIFYHKLYHMVCNKLHARCRGPVQVLTRQPTEGRAREGGLRVGEMERDTIIGHGACMVLNERLLECCDAETVHVCAE--TGYAFKLLLDEMIALGIRPKLDAGMFVEGLDGFPGPYGYVPGRIV-APRGEG-GFGYDPIF-EH-------DG---ETFAEMDTDRKKTAVARATVRDGEGRVRINELVEP-EQARLKMLEPDIEVNVEGGGFCGQADATRTAIARLRDAYMNFDRTLLVNDVRQCEPKK--WGGPGARARYQKCYRTR----GPPVYGERAWDPGRCKLLYLGAACGTTVCHVADFA---GPTYAVEFAPRVATRGQAEVAVRNGRLL--LAIKA-----RCEDVTVEPETVFEG-ALDRLVFFNPTQELN--RDDVDPDAVELAAENDLDPYGTPIPFADAALAN-ARN--LVCVTATDTAPLCGAHLNCGIRKYGAVPR-NTDYHPEMGLRTLICALVRTAARYDKAAR--PIVCHVCRHYARTYLELECGAQVADDCID-ELGLHGCPGVGKTCAAHALALRDICRKE-------GIEFECDALERIAERNRGDLRGAINDLDPCTKRYMTVTPIA--HTMGRHACKQFKKCEICLVERMINRLMGKKQQATRIVRDAFDIIHERTEENPVQILVTAVENAAPREETVRLKYGGICVPKAVDVAPQRRVDQALLFICDGVANAT-YKCTTCAAEALANELITAADYD-PERCYCICQKEERERVAAAARRG-SRTHGGGTHKNRRGAGHRGGRGAAGR---AKHEF----HNYGPL-------G--KYGFKVLGGGQVRRELRVTADAFTAGAVELIEEAGGGHCLDELQ------EMDVDEVAELLPARQRRCIVR----GIRTHLRDMPILPEFVGVTFCVYNGHCFERVQVEPEMIGHFLGEFHLTRCTVEHGQAGIGATRCCKFVPLKADNTGARELKVICVAG-Y-SGTKNRHPKAGIGDKVTVCVTKGTPE---MRRQVLEAVVVRQRKPIRRPNGTRVKFEDNAAVIIDDL-DE-PRGTEIKGPVAREVAER-FGCIACTARLAADELDVGKGRIWL--DPEAQEEIEDAITREDVRDLIDQGTIRAKDAKTNCRGRARERAEKRC-YGHQCGAGTRKGKCGARQ-NTKDDWKARIRAQRARLKELRDEEDVLDACEYRTLYNKCCGGEFEDVARLWEPRTRLGRKVQNGDICCMEQALDCGLPLKEAEIVDQLL-PGLGRRVKFRCVVAVGNRDGYLGYAQARDDQVGGAIQKAIDVAKLNIIEVDRGCGCWEDQPGGTNCLTRKAEGKAGCVTVEIQPAPQGLGLAAAETVRNILELAGVEDAWTNCDG-----NTRTTVNLAKATFNALEFFADELGRAGYGGMDVAKT-PMGTQIVLKAEKPGMVIGKGGKNIRKITTELEDRFD-MDDPQIDVQEV---DEPDLNAQIVADRLANALERGWY-FRKAGHTTIDRIMDA-GALGAEIVLCGKVTG-ARCRVEKFNRGYIKHNGEPAQEVVDHGQGVAVMKLGTIGVNVKIIPP--GAQLPDLKQYLTDGARQRLNAVAMCKPEFGDKVKQQVAALAQCGRIQGQIDEDQMRDLLHAGTLDPKVTGCLPTLTGDATRAAQVFLEGCKEYFEAEIYQKPPRKCAVRRLRTRTIYDLDV--LGTYIRKLCHDIGLATGVGAHMGHLRRTATDPFDDRDL--HPLPAEDALVHLPCVTIAPCAARNVATGAPVYAPGVACHTPDGAAVPVVERPAGHVPFKRKL-MWTAGILVVYFFLTNINPFGG--SLLQVGIGPIVTACIVLQLLGGA--NLLGLDTDD-PRDQVLYQGLQKQIFI-GGVLLLFMDEIVCKG-----VGCGVGLFIIAAVTLFIFGIVVYAECVRVEIPPVKLIYACVLPMIFAIF--WVETTGMGP-EATAKQIQNCGMQIPGFRRNPQVVEKVMERYIPQVTVIGGALVGLLAVMANLL---GTIGQV-----SGTGLLLAVCITYKLYEEIAEEQLMEMHPLRAADAVRFGE---FELCHGGTCYVDKYLFETDPP--Y--VIARKQAKGTGNR--IEG-RLD--EGEEVVVLEDIATTGQCAVDAVEALREAGGKYAARKLKQDRQKRRWCDCEYARRER-GLKKKCDPLEGA------PQARGIVLEKVGIEAKQPNCAIRKVRVQLIKNGKQVTAFCPGDGAICFIDEHDEVTIAGIGGAKG-RAMGDLCGVNYKVEK--VNGVCMIELVRGN----AEKPVRLIPVEDYL-----SAGVHIGTQQK--TKDMER--FIHRVRD-DGLYVLDVCTTDQRIRTAADFLKNY--NPEQILVTCCRQYGRFPAEKFADAIGARARTGRFIPGTLTNPDYAGYIE--------PDVVVVTDPIGDAQAVKEAITVGIPVIAMCDCNNQLCNVDLVIPTNNKGRRALCVVYWLLAN-ET---LDRRKQAIVARTDIGMGEGKLAAQVAHAWQGEGQKKVVLKGDCECQLFELADKADKEGIPYAIIRDAGHTQLEPGTVTALAVGPARDDTVDRVTGDLCLKFVFVTGGVMCGLGKGITAACTGRLLANAGFDVTAVKVDPYLNVDAGTMNPYEHGEVYVLKD--------G-----GEVDLDLGNYERFLGTDMTFDHNVTTGKTYQHVIERERAGDYLGKTVQIIPHVTDDIKRRIDVCLIEIGGTVGDIECMPFLEALRQFAHEEDDEDILFTHVTLVPYCKN-GEQKTKPTQHCVKELRCIGLQPDILVGRCEDRLDPETKEKIALFCDVPTDAVFCNPDVKDIYHVPLMVEDEGLEDAYMCIHEALKHDAVVVPGGFGCRGTDGKIEAIRYARENDVPFLGLCLGFQMAVVEHARNVLGLEGAHCAEIDPDTPHPVQYET----EDMGGTMRLGAHKTDIEPGTLAARVY-DADCCTERHRHRYEVNPE-YIDRLEAGG-----LTFC----G---RADNRMEILER--AD--HPFFLGTQAHPEFRCRPDRACPPFRNFRETVDIAINLRDLDLND-PCNRIDECVVLPAGTG-QETQIVVFAEGETAVRAQEV-ADQVLDCDDLEDLGDDDDRAKDLADETDFFVAEANLMQDIGRYL-GTVLGPRGKMPVQLRCRDRRTFHTRVGAEDMGPDAICDNIDVIIRRLEACLEKGPL--NIDGIYVKTTMGMCT-GKN-TKGYET--PNHPYQGERIAEECDLLCRYGLK---NKEEFWRAQCELRCM-RR--EARRLLRRIGIL---GDNDDICAVLCLDVTDLLERRLQTVAYRQGFACCTQQARQFIVHGHITVDGARVTRPCVKVDVDDEGAIIEHPIVTEQAMNEMDFKNKLLFLVDIDATKPEVREEVQDRYDVCVVDVNTKKAIVTLCEDD--DATEIACRIGVHDLDGGDAGCVEL-PAIFETAFRPDLIGRAVCAAQANRKQAYGADEFAGLRTPA------ECFGC--GRGLAHIP-R--SENV--------ARRVPNAVCGRAAHPPKAEKDQTKCLNDKERQLAIRCAIAATADAETVAERGHAFDEDLDL--PLVVCDEFED-LNKTQEALGVLEAVGADADIERAEEGR-SVRAGRGKTRGRKYCQPKCVLVVNLCGVDVATAREVNAEDLAPGAHPGRLTLWTECAARLECHGERFEVLIDPDAALAMK--RGEFE-GNLEDVIAAEDVFENACRGDRPAEEDLETVFGTTDPLEIIPEVVERGEIQITAEQREEMMERKHNQLVTTITRNAVNPQMDDCPHPPERIERALEEAGFQIDPMEPVENQVDDALEALRPVIPIRFEEVTMAVQLPADYAGCGQAQIREFG--DLEREEWQNDGCWVGVL-TFPAGLQNDLYDLVNEVTCGVCKIRDGTVIDHVEGGQA--------LNVLAILGIDG-SEGYG--VCVGMNVPCDRLG-R-KDIVKVEERELCQCEVDVLCLIAPEATINIVRDFEVVEKNRVTRPDCVTGV--LCCPNRNCITNAG--EPIDTRFDVV-----ADGVRCDYCTNPKLQNLIADLKCVCRDCGANVWQDIAARLEKPRRTHA--EVNLGRIERYAQED-----ETVVVPGKVLGCGVLEKN-VTVAAVDFCGTARTKIDQA-GEA--VCLEQFVE--QNPEECNVRVPVRCFTCGNVVGEHWEEFKERA--REGDE--DP-----GKVLDELGVDRHCCRRMMVCHLQEGCYVMM------DCCPCKINHYCTAKPGKHGCAKARVEGKGVFDEKKRCLCQPVDAKVWVPIIQRKQGQVQVMDLDTYETDDNIEYLEY-EGQRKVKYLIHANIAADGVVDV-----VGAFGQTEGLLGDEL----DLRDLQECCRVGRIA---AALETIDR--------IGPCHACVEVTCIEDVRAAKRREVVERAVGDCDAVIVVEGRAD------VLTLLE--CGIKNAVAGTN--VPDAVADLTADRTV--TAFLDGD--------RGGEL------ILRELAQV-GDVD---YVAFAPPGE-SVEDLDRNT----VFEALDVAAQR--GVCELLGREVG-EF-VKRPMREPYLEKVVVHMGVGQG---GEPLADAEEIIEEIT-DQQCVRTTCKRTIAEFGIRKGDPIGVKVTLRGEDAHAFL-DTALE--LA---D---ICKCQFDDTGNLCFGVEDHTDFPCQEYDPNIGIYGRIAVARPPEITAVRP-IAKTTLDDYVLICGCPGAGKCTFAQAVAEFLNDN-DY-AVKTMEKPRDLQVGP---EITQYGALGG------QMEKTADCL--------LLVRPDYTIYDEVRKTNDFEVFCDMRMAGV-GMVGVVHACRAIDALQRLVGRVELGMIPQI---VDTVVYIEAGEVHTVYDVTTEVKVPAGLTA--EDLAR-------PV-IQVCNF--ETGRPEY-EGRCTRKRTGG-RLKHACN-KKRHQLGREPAETTVG--ET--RVQYIDCRGNEKKVRALCTNVAQVAD--GDAVCEAEIENVVDNPCNVNYARRNIITKGAIIETCAGRARVCCRPGQTGQVNAVLAGAVLVEAMNEAREMVEPGRTHLEVAEWTEDFIR-EQDAGLA------FP--VNICVDPEACHATPCRDDDTEFGE-EMVCLDVGVHVDGYIADAAVTLVEAAEMALEAAVDEAGPGVEVGVVGQAIEDVIRGYGYTPVLNLCGHGVERYDAHTGPT-VPNGQAVAIEPFAT--DGRGKVGEGTEEEILKEADDALVCQAEHTLLVTDDGVEITTCQ-PDRCN-YECANYCPICEEICLGETCGICVEKCPFDAIEIINLPCELDEE-PVHRYGDNAFCLYGLPT-PKPGNVTGILGPNGIGKCTAVHALAGEMVPNKPQ-----YVDQ---IPNQF--DGN-TRELLERTDER---G-ALDCLIDRLNIRPVMDQPIDCICGGELQRVAIAACLARDADFYFLDEITPYLDIGQRMIVARLIRELAD-DDAAERCMLVVEHDLAILDLLADTLHVAYGEP--GAYGVVTDPKCVRNGINEYLKG----YLDNENMRIRFELHVEGGE-INRCEVLGVVGPNGIGKCTLAKLFAG--SLEPDE------GY-------KPQYI-DID---QPMRVDVFLLCGGERQRVAIAACLCEDADLYLLDEPCAHLDVEQRVRATTAIRRYAENHDATVMVIDH--------D
'Ignicoccus hospitalis KIN4/I'                          GAE-VYLAGCNPLCT-----QDAWKGETEEEYWWAIKKIIE----EGDPDLVIDDGGDLHATIHGGTEETTTGVIRLKAMEKEGVLKYPVIAVNDAFTKFLFDNRYGTGQCTIDGILRATNILLAGKVAVVAGYGW-VGRGIAMRLRGMGAR-VVVTEPLRALEAVHDGFDVM-RMDDADLFVTATGNIHVIRKEHILKMKDGAILANAGHFNVEIDVKALEEI-AICKRRIRPY-VDE--------YKLPD-GRRIYLLAEGRLVNLVA--AEGHPCEVMDMCFANQVYKVPAEIDEEVARRKLEAMGIKIDCLTEEQVRYLNCWDIGDLEEAKERLREIVE-LPMKHPEIFRHLGIEPPKGVLLYGPPGTGKTMLAKALANEI-----GAYFIAINGPEIMCKYYGECEQRLREIFEEARKNAP------SIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLQERG------RVVVIGATNRPDAIDPALRRPGRFDREIEIPPPDKRARKAILGADLAALVKEAAMNALRGPPGTGKTLLAKA---AATECQANFIAVRGP--EILCKWVDEIDCIAARRGKD--VCGVIDRIVNQLLTEMDG--IEPLQRVTVIAATNRPDLLDPALLRPGRFDRGVAHIFCCPNNTFVHITDITGCETACRVTGGMVVKADHEKPCPYAAMIAAARAAQQAMERGITAIHIKVRAPGGY-GPKTPGPGAQAAIRALARCGFIIGRIEDVTPLPHDTIRRPGGRRGRRGIAGRFGARYGCTLRKQWKQVMEARYAPHTCPYCGIKGYVKRIAVGLWKCEKCGRVFAGAAYVPVDKGAVPYVTRGADVMRPGIICFEGDFKKGDVVGKVIKNLHYLGDYHFLREQWKRPFD-GEHGELMKQRIIKWRREPAVVRIEKPTRLDRARALGYKAKQGVVVVRVRVRKGGLNRPRPNKGRRPKRMGVYGYAP-AKCTRLIAEERAARKYPGLEVLNCYWVAEDGEYEWYEVILVDPHHPAICCDPELKWICEKQHRGRVFRGKTCAGRKMRGLVVELKHDPGRWVPLAHIVIP---NVADFWIPAAEGMYTGQKVGPNAAPVNGNILPLYAIPEGTQIFNVEIRPGDGGKLARCGGAYALPCGKVKQVNAKARATIGIAAGAGRDEKPLLKAGNAYYKWKAKAKKWPVVRGVAMNAVNHPHGGGNHQC-PG--YPTTVAR-NAPPGQKVGHIAARRNIGIIAHVDHGKTTTCDALLAHAGILCP--KLAGEARALDYLDVEQQRGITVKAANVCLYHEYKGKP----YVINLIDTPGHVDFCGKVTRCLRVLDGAILVVDAVEGVMTQTETVLRQALEELVRPLLFINKVDRLIKELKLCPQEIQQRIVQIIKDVNERILDMVVRWVPNPREAQKYRVPRLWKGDINCELGKAMLNCDPEGPLVVFINDMRLDPHTKRLVATGRVWAGTATAGKEVWLVNA-QKPGKILQVCIYMGPDREIVDYVTAGNIVAMLGLDDARAGETEQLHYVCEPVVTVAIEPKNPRDLPKLIEALRTLCIEDPNLKVTINQETGEYLLCGMGMLHIEIALT-QLKEVYGLEVKVCPPVITYRETVRKPG-EKVEGK------SPNKHNKLYITVEPGVQHLREVKDTILAGWRLAMKEGPLAKEPVRGVKVILWDAVIHEDPAHRGPAQLYPAVRNAVYACMLTDCPTLLEPWQKLDIRVPNEYIGAVTGVITKHRGKILEVIDMGGQ-ARIVAAVPIAECFE-LPMELRCVTAGRAFWGTEFYGWEPVPDTLANALTTIYNNEVRGNKEAIIMPACKLIANVLRIMQKEGYVGEFEYID-DGK-IRVRLLGR---INKCG-------AIKPRVCVCYRDLLVLPEHLR-RFLP--SKDVGILIICTCQGLMTHKEAIQKRVGGIAIAYVYGAAQVVLFGIPNCGKCCIIAATTPGVA-----PGVGWVHRCIG-LVRNADLR-------AYGIHCALGCTIFKVLDIIRVYTKKPNGPKA-EKPFKF-----AKVGLDHQVED----GDMITPREVPPERFNQRLAMYLKERFPEIRPPEWAMYAKTGCFKDRPPLDE-D-WWYYRAACILRKLYLAGRPLGIETFRTIYGGRQR--RG--VAPPHFRKAGGCHIRKILQQLEKAGLVKKVKG--QGRVLTPAGRCVLDHVADATNQIVGRMACHIAGWE-VNVINAEKAVLCGEPTRVVKGYQ-ILLNVKTHTNPYRNKIKRPRTPIAIIKDAVKGMLPK-HNTRGGNAKPAPPIKPALECVGLDPNEVVQKINEVTKRYK--GFTVT-VKVIV-DPDTKEYEIEVEPPNITELLLKLAGAKA------PCGDPIH-QKVGDLPFEKVIEAALLKAPELTAKTLKGAVKTVLGTARAIGLTVDKMDPKEVTRLVEEGKVGMTHVIMIDDREHVDTAGQEIFVPVTVIETPPMVVLGARV-YGYDPNRG-RYALTEGQLVDVEEVIEAGKFVDVIGVTKGKGFQGVIKRFGVKELP-KWHKHRKGCRR-VGARC--WGKG-TCCYVPQPGQMGYHRRTDYNGWLHYGLVKCKYVVLKGCVFGPPKRPIIMRLPVRG-GIHPREAARHHAYCAGPGLGPCLRTGAVMARALAAFYEKPLVPVNHCLAHIEIARAVT-----GFCKP-VAIYVCGGCTIICAPAI-KRYRV-YGETLDIGLGNLLDTFAREVGIGPPFVKGGVHVVELCCE------GA--EEPADLPYTVQG-----VDLCFCGLLTETAYDMVVEVGERAGGVAGCKRLQRKVALM-SEERGVCFKPIPYELARDNGAMIAWTGLLYYKHGRIKMWCTDVKCIEEVAKQIREIAERCGVEVRGPVPLPVKRLEICTLRLPHGEGTKVFDHWEMRIHKRLIDV-ELNDKVMRNIMRIRV---PCNVYIEIIKFGILCPDEIRKMAVVAVVTDQAYDEAGM-PVEGGIMDPRM-GVTCPGQRCPTCGNTLHDC---PGHFGYIELVKPVIHYEFVP----HIYDALRATCRVCPH-------CRCRLENIPD--KDR----PEWAVLTVLPVPPVTVRPCIILETGMRCEDDLTHKLADIVRTNNKLRENIECGACEAMIENLWGLLQYHVATFFDNEIPGI------PPARHR-SGKPLRTLAQRLKGKEGRFRCNLCGKRVDFCARTVICPDPNICINEVGVPIEVAKTLTVPVKVTPWNIEEMRKLVINGPDKWP-------GANYVERHLQDGDVVLFNRQPCLHRMCIMAHLVRVLPGKTFRLCPLVCPYNADFDGDEMNLHVPQCEEARAEALELMLV-EKHILCPRYGGPII--GGLQDYICGAYLLTGKQLFCVFLPDGFKNGLLEPLPGRTLEETLELMINNAVIMAKAGARGNILNLTQMAALLGQQCVR--------GERIKRGRTLPHFEWGDI-SPDARGFVKHCFYEGLTPTEVFFHAAGGREGLVDTAVRTCQCGYMQRRLINALQDMVK--VLVVAKVYPDCVERNLEEMV-PVAFGLNLLKVYVAMPEETEGGTEKLEEVLKGVEGVVRGPKGELERDFCHAKGIRIRVVEEEGKKQVTVAAHIKNMITGVTKGWRYKMKIVFCHFPICVKVVGDR--VEIHNFIGEKAPRVAKVL-P-GVTVKV---QG-RD-VIIEGTDIEKVAQTAANIGIDEAGRGPVIGCMFVALVECKMLTPNKRRYFYNLIDACCPAAAAACIVAKEARERHVCQLRA---RYGGRVMRPVFVVE---NGGIVELLDADEGVVACTIPYLEHNQCPRNCYQCAMAKQGLYAAN-FMLRTDTRGYLLHY-PEKPAQTKHLEIIG--YNKRPA--------GQNAVAAYTGYNIEDAIIMNQCCIDRGFMRATFMRLYQTEEQKYPGGD-KIEKP--KPDQRLVGMREPKAYEKLDE-DGIVEPETYVRFT--EEYKEMG-IL--ETRRRDACRHGEEGVVDTVMVKVRVRCLRGDKFACRHGQKGVIGMVLPHYDMPYCENPHAFPCRMGQLIECIAA-------KGTEVMFDGRTGEMIARPVFIGVVFYQRLYHMVCDKIHARARGPVQILTRQPTEGRTRKGGLRFGEMERDVLVAHGACQLLVERLLKCCDATKVWVCAK--CGYAFKLLIQEILCMGIAARLDCGLFVDALKGFPGPYGEVEGEIAYEPRGDK-GFGFDPIF-VP-------LGYE-KTFAELGEEVKKRAIARAIIYPGKGRVWINEIVKP-EIKRWRILEPDIKVFVKGGGFMAQAEAARMAIARLKALYEEHDRHMLCGDPRRTEPEK--WMRYCARRRKQKCYRTKNLTPGHRVYGEREWNVQRCKLLYLGAATGTTPCHICDIIGEEGRLYGVEFAPRVAQPNQAEIVADNGYML--MAIKA-----RCVDVTKCPEEVFKR-EIGVLVFYNPKAKFN--RDDADPKAVELIKYNDVDPFGCPMPFADGAIRA-ARRRGLVAFTATDTAPLTGARPQCALRKYGACVR-RTPFCKEVAIRVLIAALVRVAAVREVALK--PEAAFFKDYYVRAHLTVERGARRVEEALC-QLGLWGPPGVGKTCLVEAICLLKICEKE-------GVYCEKEAVDYIIEKNKGDLRACINDLDPCLKKYICLKPVWTPYTAGRHEKRRFGKAEVPIVERLINKLMGKKAKLYCVVERAFDLIYLMTGQNPLQVLVRAIENCAPREETTRIMYGGIVYHVAVDVCPQRRVDLALRFLTEGARMKA-FKCQKPLEETLAEEIVAAANDD-PK-SYAIQKKEEIERIALCCRRGRTRTMGWGRIGQHRRCGARGGFGRAGM---HKHFWT-WVTAKCPG-----YFG--KYGFKLLGFGKVKGCYTVIVAFACKKAIQKVKAAGGGKTLEELL------EMPLDDFIELLPARQRRCLKR----GIRTHVRDMVILPIMVGLTIEVYNGKEFVPVKIVPEMIGHYLGEFCHTTAVVKHGEPGLKATRCCLFVAAKTDNCGAKVAMIIGVPG-Y-HGRLRRIPPAGVGDMVVVTVKKGTPE---MRHQVVRAIVVRQRKPFRRPDGTWVAFEDNAVVIVCED-GT-PRGCEIRGPVAREAVER-WPRIGNVARLAAEILGVGECRIWI--DPTRLADVCEAVCKEDVRRLIEEGAIKVEPKRRNCRARWKVRHEQRK-KGRRRGYGKRKGKACARQ-DPKEAWMNRIRKIRRFLRYLRDHEV-IDRRTYRELYMKAKGGMFDCLCNLWVPRTRVGRMVKEGKITCIYELFEKNLPILEPEIVDYLV-PDLGRVTRLRVLVVIGNEDGLVGLGMGKAKQMRFAIQKALANAKLNITPVRRGCGCWECTCGEPHCVPFTVRGKCGCVEVILKPAPRGTGLVAGDVAKAVLRYAGIKDVWTHTEG-----ETRTTHNFAKATFNALEYLAYKFHCVGYCKVELQKT-PMGTRVIIYAERCGAIIGRRGQTIKQITKVLEEWFG-IPNPQVTVVKV---EEPELDARVMAFRLANALQRGFH-FRRAAYTTLRRIMGA-GAIGAQVKVCGKLRG-ERARFEKYIAGKVYKCGNQVVRLTDRAIAHVLLKVGVEGVEVIICKKCEEERPDDLKCILTCEARARLANVKLVRPELAEQVENYLIALAQAGRIARPLTDAEVKEILHGGTLDPKVTGVLPVALAEATKVIHYVMLCGKEYLVGEIYQRPPLRCCVRQLRTKKVYYIHV--LGTYMRKLAHDLGLLVGTGAHMRELRRTRCGPFHEDWNL-VRMPCEVATCHMPKIMIKDGAVDAVAHGANVCIRGVAVVCLKGELVPAVPRPKRKINLYKRL-TWTALALVAYLMMCNIPLPGG--TLMQLGIGPIVTAGLVLQLLVGA--KIIDLDLTD-PEDKKLFTLAQKLLLAGATILVIIMDEMIQKG-----LGCGICLFIAACVTVVMIAAIAYLCCVKIQVPPLNLLYVTNIPVLFGYL--WVELAGLDP-KTQARNLIECGLHVPGARCDPRHLEKILAKYIYPLTILCCIIVALLVIVADIF---GAYG-------TGTGLLLATMILQQYYTMLTYERAIETYPIQECGLVKRGT---FILCCGKRCYVDMRKLWCFPP--M--GYARPKRKGQMRL--VEG--VE--PGQKVVVVDDVTTTGGCLAKTIDALRDFGGLFAARKLERKRLKFRWCQREFKRRML-KLKEKYDPLEGA------PMARGIVLEKVGVEARKPNCAVRKVRVQLVKNGKVVTAFVPGDGGLNVICEHDEVVIVGIGGPRG-RCMGDIPGVRYKVVL--VNGVCLDAILKGK----KQKPVRLIPLEMYL-----QHGVHIGTKMV--TNYMKR--FVYKRRNIDGLAILDVRKIDQRIRVAAKFLCRF--EPEKIMVVCVRQYGHKPVTMFAQFTGAKPVIGRFVPGTLTNPALEVYYE--------PDVILVTDTRMDQQAIVEAAEIGIPVVAICDTDNKTENVDLIIPGNNKGRKCLALLYWLLTR-QV---LVER-----------MGKGKICAQVAHAWTKGGQKKVVLKVGCLKELLEIYQKARDLGLPAFLVKDAGLTQVEPGTVTAVAVGPAPEEEVDKVTGHLKL--------MLCCLGKGILTACTALFFKCMGYTTTAIKIDPYVNVDACTMNPYAHGEVFVTED--------G-----GETDLDLGHYERFLHQNLTKNNNITTGKVYLNVIEKERKGEYLGQTVQIIPHVTDEIKRMIDVAVVEIGGTVGDIEGLPFLEAARQMWVERR-GDVAFVHVALVPVLCTTGEQKTKPLQHCVQELRRIGIQPHVVVGRCTKPLEPETKRKIALYCNLPEEAVFCDPDVEFVYEVPLRLAEQGLKDCYLCIIECLKHDGAIILPGFGKRGAEGKIAVIKELRERGVPTLGICFGMQMMVVEVARHLAGLEGANCEEVDPNTPHPVQRKL----KYLGGTMRLGAKPVIIMKGTKLWEAY-KKTLVKERHRHRYDVNPK-YLDKLEEAG-----LRVC----AWC---EGVPEGVEL--EG--QEFW-GVQYHPEFKCRPLQPCPVYRNFKECVDMIVVLKDIDLKG-PEGRIREVVELPHAPK-KEVKICVVAHGDLALQAKKMGLT-VVTRDELQQM--DKKAAKKLAKRCDWVLVQTDLMGIAGKVL-GPALGPRGKAPVNLRIRKQPQVMCCIGTEDMDPKELAENAAAVLGALERKLPNPQN--QIAKVIVKTTMGMGDPRKP-RKKWCP--PGHPWVKERLIEEMKLMGEYGLR---NKREIWIAAAMLRRY-RH--RARELLYDLGLV---DENATLDDVLCLTVRDLLERRLQTVVYKKGLAKCIYHARQLVTHGHIAINGRRVTCPGYIVRRDEEELIIIRPLHTEKALMLMEKYNTLTFIVRRDATKPEIKYAVEKLYNVKVEKVNTKKAYVKLCPEY--KATDIACRIGVWDLNGNPVEEIEL-PPVFCLPVRKDLIRRAFLCAFTARLQPKGRDPMAGKRTTA------ECLGP--GHGLARVP-R--IKGTC-----R-AAFVNCARGGHLAFPPRPDKKLHEEINKKERLIAIACALAATCRRELVEARGHAICCVKEV--PLIVVDDIEN-IEKAKDLREAFVKLGVIDDVERACEW--RQRCTKGKMRGRRYKKRVGPLIIAFPGTDVVAVNLLCVKHLAPGGVPGRLTIICKKAARYEYKGHKFEILVDPDKALELK--SGK-Q-IPIEEVLIADTIYKDVGCGDRVCPETLKKVFGTDDVKKVALEIITKGEIQLTAEQRRKIIEQKKRQIINYIAKNAIDPQ-TKLPIPPARIEAAMERAKVGVDPYKCVEEQAMQIVRAICRIIPIKIAKAIIQVKIPPKYCGRAYCELKKLG--EIKCMDWKCDGCLVAEI-EIPAGLQGEIMDKLAKMTKGVCKINNGTVIDHLPPGRA--------LKVLRLLGIDG-SEGFM--VLIAMNVYCKKLGGR-KDIVKIENVYLCDEQTKALALIAPTATINIIRNGEVVEKRGVTLPDVVEGI--LTCPNCCCICRCKR-EPIKCKFLVV-SKR-PLKLKCHYCTNVLLRKTLDELWKT----KCPAWRRVYELLNRPARQRI--VVNVCKINRYANDG-----DVVVVPGKVLGCGELEKK-VTVAAFCFCYTALEKIETAGGKA--LHILELVK--ENPKGCGIKIPIRCYTCGRPLWPEYEEFLRRV--EAGE---EP-----GKVLDDLGIKRYCCRRTMLCALKPGNFIMI------DGEPCKIVEMCKAKTGKHGCAKAHVVAICLICGAKKTFVAPVDTRVEVPIIEKRVGQVQLMDMETYDTGVEVEYWVMPPGVYKIKYIIKALVEVDGPVDI-----IGAFGQTEGLL-DDF----DLRELQEKGRIGRIA---AMLECVDK--------VGPYPARICVVEIIDVRAEKIKKIIERAVERCDTIIIVEGRAD------VLNLLR--YGYDNVIAGATTKVPETIKKLAKEKIA--IAFVDGD--------RGGLM------VLKNLLCQ-ADID---YVARAPPGK-EVEDLTARE----IAKCLDVMCLK--GGRLILGRRVA-RV-SKRPMLKPRLAKVTVNIALGEC---GERLEKAYNLLEELT-GQRPVKRKAKKTIRQFGIRRGENIAVMVTLRGQRAVEFL-KKALE--AV---GWK-IKACCFDEFGNVGFGIREHIQIPGTRYDPRVGIFGRIVITRPPEITAVRP-IAKLCLEDYILIAGAPGAGKTTFAQALTEYYARK-GK-VVKTIECPRDMVLPP---SVTQYCKEHT------SVKELYAIL--------LLCRPDYTIFDEMRTDEDFKLYMDLRMAGI-GMVGVVHATTPIDAVQRLIGRVELGMIPCI---VDTVIFIDCGCVAKVYELQMTVKLPTGLRE--ADLAR-------PV-VEVRDF--LTGELEY-EGPDLKKITGG-KKRRHRKVKRKYWMGRYPTNTTLA--ENE-KRKIERVRGGNIKVRLRYAAYANVVDPNENVAKKVKILRVLETPANKELARHGIIVKGTKIETELGVAVVTCRPGQDGVINAVLCGEAVRRALERGRELIRPGACVLEICEEVEDLIR-KLCDGPA------FP--CNLCVGYEAAHYCPVPEDPKRLPEKGIVKLDLGAHVRGRIADCAICLCEAVKEALERALERARPGLCVCAIGTTICVTIRRKGFKPICNLGGHGLAPYLVHCGVC-IPNGRAYAIEPFGT--DGAGYVVEGKEVTILIEAKRGEVAQWEHTIFVTEEGVVVTTCK-PDKCN-YECIRFCPIHELVCTG--CGICIKKCPFQAIHIENLPEEVEEK-LVHRYGKNGFALYGLPV-PKRGQVTGIIGRNGAGKCTCLKILCGLLKPNKLQ-----YVAE---AAKLL--KGT-VGQLLARVDER---G-IAREVAQALNIAHLWERDVRKLCGGELQRFLIAAVLCKDADLYAFDEPAAYLDVKERINMARAIKKFVP----PNRYVLIIEHDLAILDYLCDLVHIVYGVP--GVYGIVCQPYCTRVGINHYIRG----FLPCENMRIRFVLEVNPGE-IHRGEIIGILGPNGIGKCTFIKLIAG--ILKPDN------AY-------KPQYV-THEMFGKNETVKDVLLCGGELQKLAVAVTLGKEADLYLLDEPCAFLDVEERLAVGDAIRHIVEGCGAAAFVVDH--------D
Metallosphaera_sedula_DSM_5348                          GAE-VCLAACNPLCT-----QDAWKGENEQDYYDNIRCIVE-----TKPQIVMDDGGDLHAYLHGGTEETTTGVVRLKAMEEDGVLKYPVIAVNNAFTKYLFDNRFGTGQCAIDGVLRATNILIAGKICVVAGYGW-VGRGIACRLRGLGGR-VIVVEPLRALEAVMEGFEVM-TMKEADLFITATGNIRAICKEHILNMKDGAILANAGHFNVEIDVDGLRKM-AKCRRIIRPY-TEE--------NVLCD-GRRIYLLADGRLVNLAA--GEGHPCEVMDLCFCNQVYDVPQDIDERVAKLKLDCMGIQVEQLTKEQVEYCKQWDIGDLDEVKEKLREMIE-LPMKHPELFQHLGIEPPKGVLLYGPPGVGKTLLARALANEI-----GAYFVTINGPEIMCKFYGECEQRLREIFDDADKNAP------SIIFIDEIDAIAPKREEVTGEVEKRVVCQLLTLMDGIKGRG------RIVVIGATNRPDAVDQALRRPGRFDREIEIRPPDTKARKEILGADIAALAKEAAMHALRGPPGTGKTMLAKA---VATECGANFIAVRGP--EVLCKWVDEIDCIAPMRGMG-HDCGVTERMVNQLLCEMDG--IVPLCKVVVIAATNRPDIIDPALLRPGRFDRGLARIYACQNNTIITITDITGAEVICKACGGMMVKADREKPCPYAAMLAANKAACDALDKGLMAIHIKVRAPGGA-GPKTPGPGAQPAIRCLARCGFIIGRIEDVTPIPHDTIRRPGGRRGRRRIAGRFGARYGCCLRKKWCEIMEKRYADHTCPVCKTTGKVYRIACGVWCCKKCGCKWAGQAYTPIDEGAVKAVARGADLYAPGVVEHCGDVKPGRLLGKVACALHWIGDYCFMACTWACE---EWKKTVIRQRLVEWRNQNTVTRIEKPTRLDRARALGYKAKQGIIVARVKVEKGGMDKQRPNCGRRPKRMGVYGFCP-AKCLQFIAEEKAARKFPGLEVLGCYYVAEDGKYKYYEVILVDPHNPVIMCDPQFNWLKNPANRGRVFRGLTCAGRRTRGLVVDILHNPGMTEPVAKVKLD---TGIQFFIPAVQGLICGQKIGEGCPACLGNIVPAKDLPEGVYVCNVELHRGDGGRYARTAGCYALPCGKIKEIDENALVTVGTVAGGGVLEKPLLKAGNNYWKYKVKATKWPDVRGVAMNVVCHPHGGGLHQC-VC--RCCTVAR-NTPPGRKVGHIAARRNIGIIAHVDHGKTTTCDQLLAACGIICP--KVAGEALALDYLCVEQQRGITVKAANVCLYHEVEGKG----YVINLIDTPGHVDFCGRVTRCLRVLDGCIVVVDCVEGVMTQTETVLRQCLEERVRPILFVNKVDRLVKELKLGPQEMMQKLMDIIKEVNNLILDAVIKFVPNPVDAQKYRIPKIWKGDLDNELAKCMLNADPNGPVVMMITDMKVDPHAG-LVATGRVFCGTIRPGCEVWLVNA-KAPQKVLQVCIYMGQFRELADEIPAGNIAAVLGLERARCGETEKLHYVCEPVVTIAVEPKNPKDLTKMIDALRKLCIEDPNLVVKINEETGEYLLCGMGFLHVEVCLQ-LLKDNYGVDVVTTPPIVVYRECVRNKC-QVFEGK------SPNKHNKFYICVEPGVQHLREIMDTMLQGYRLAMREGPLAHEPIRGVKVILHDATIHEDPAHRGPAQIYPAVRNAIFAAMLMCKPTLLEPLQKLDIRVPMEFVGNVTAVLCRKRGKVLNMTQCGCV-ARILAEIPVCECYE-LACDLRGCTGGRAFWGTEFCKWAPVPNTLCNALCCLYNNEMRRNKQAIIMPCCKLIVNVLRVMQKEGYVGEFEYID-DGK-ILVQLMGR---INKCG-------AITPRYCLTYREMICLPDYIR-RYLP--SKEIGVIIVCTPKGVMTHKEAARQRTGGIVLGYVYGAGQVLVLGREEL-KNPLVRRLTPQII----LDCRLIVCKLLG-LARNADLR-------EFGIKCALRRELYLCLDVIRIYTKEPMEEPT-KDPFKY-----ARVGEDHVLED----KDMITANMVPPDLLVKRLCDYIKNNVCEVQPPDWCLITKTACFKERIPDDP-QCWWYMRAACILRKLYVLE-HFGVCECTRLYGGLKR--RG--TKPPVCARAPGHCTRLIFQQLERAGLVAKTRGARKGRVLTPKGRCLLDKMADGEGQILGRLACKVVGKR-VVIVNGEKIVICGPRNRVVNGYM-LLFCVGTLFNPYKLGVRRPRTPINIVKRTIRGMLP--KTHRGGNVKPGPPLAPTLCQLGLNVGEVVKKINEATCQFK--GMTVP-VTLDV-DTDTKKYEVCVGVPTTTCLLVKKAGACG------PCGDPEH-KKIGNICMDDVIEVAICKKPCLTAKELKGAVKCILGTAKCIGLTVDNKDPKLVVREVEEGKVGMTHIFMIDEDRCCCMFGKEIYVPVTVLETPPIYVLALRA-YGLNNRGE-HCVMGEGNTLCVRDVFKEGQLMDIIGVTKGHGFQGVIKRYGVQELP-RWHKHRKGCRK-VGTKGP---SLGTPCYVPQPGQMGFHRRTEYNGFVRYGLVKNTYLLVQGCTIGCIKRPLFLRYPIRG-GMKPCEAARHHAVALGPGMGPTLRVGAVVARALCLRFNKKLVPVNHGIGHIEIGYLTT-----EAKDP-LILYLCGGNTIITTYYR-RRFRI-FGETLDIALGNMMDTFVREVGLAPPYIVDGKHKIDICAE------QG--SCIIDLPYTVKG-----EDMCFCGLLTEIAYGMLLEATERAGGVAACGCLRCKLEKL-SNDWGVGLKVVPTCFAGDNGAMIAYAGLLALKHGRIRLWCTNVNNLNYVVNQIKGIVDKTGVCMRGPIPLPTRRMEVPVMRLPHGEGRKKWEKWEMCLHKRIIDI-SADERVMRQLMRVKV---PEDVYIEIVRFGILCPDEIRKMCVTAIITADVYDEDGT-PIEGCVMDCRL-GIIEPGQKCPICGNVIGNC---PGHFGHIELVRPVIHVGFVK----HVYDLLRCTCRRCPH-------CRERLERIPD--SDR----PEWIILTVLPVPPITIRPCIMIECGIRAEDDLTHKLVDIVRINERLKECIDAGAPQLIVEDLWDLLQYHVATYFDNEIPGL------PTCKHR-SGRPLRTLAQRLKGKEGRFRGNLCGKRVDFCARTVICPDPNICIDEVGVPYDVAQILTVPEKVTKWNIERMRQYVINGPDKWP-------GANYVERHLVDGDIVIFNRQPCLHRICMMGHKVRVLPGRTFRLNLLVCPYNADFDGDEMNLHVPQCEEAIAETKELMTV-HRNILTPRYGGPII--GCAQDYICGAYLLTGKQIVCHFLPDGYEKGQLEVIPGRTLEECLECYINNAYIMARTGARGCVLNITQMAAMLGQQCVR--------GERIKRGRTLPHFKPGDI-TPEARGFIYCCFRCGLNPIETFFHAAGGREGLVDTAVRTCQCGYMQRRLINALCDMTD--VMVVLKVFPEGDETDLEKVE-PIAFGLKALVVYVCMPEKTEGGTDTLEELACCIEGVVKGKKGELCRDFCFAKFLTICLEDGK----ICIVKHIKNMFTGVQNGYRYYLKIIFTHFPITVKVVNDE--VQITNLIGEKNVRVAKIM-P-GVKVTV---KG-ED-IVVEGIDLEKVCQTAANIGIDEAGRGCLIGPMVVVGVDCKKLTRKKREELFDLIDELFVEACCACIVAKVIRDRLIECLKK---EFGGRVRRPLIVVK---HGGKIEFLDAEEGITACIIPYPEHNQCPRNTYQCAMAKQGLYAAN-YQIRTDTRAHLLHY-PQKPVQTRALEAIG--YTERPA--------GNNAIFAYTGYNMEDAVIMNKCCVDRGMFRCTFFRLYCAEEIKYPGGD-EILLP--EPGVR--GYKGKDYYRLLEC-NGIVCPEVDVRFL--QEFKEL--SP--DQAKRDTCRHGERGTVDLVLVKVRVRDLRGDKFATRHGQKGVIGMLIPQVDMPYTTNPHALPCRMGQIMEAIAG-------KGCEVVYDGRTGEKLKGRILFGIVYYQKLHHMVADKMHGRGRGPVQILTRQPTEGRAREGGLRFGEMERDCLIGYGAAMLIKDRLLDNCDRATVYVCEQ--CGYAFKLLLQELMCMVIAPKLDCGLFVEALKGFPGPYGEIFGKIAENVRGNK-GFGFDPIF-VP-------DGYG-ITFGEMELCEKKMARAKCYLFPGKGRIFVNELIPV-EVIRMKIMEPDVKIYTYGGGIMGQADAARMALARLKELYKKYDRTMMAGDPRQTEAEK--WMRYCARRWRQKCYRTKNLAKGFTVYGEREWNAFRCKLLYLGAACGTTPCHICDIVECEGKVYGVEFCPRIAQPDQTDIAIYNGHLL--LAIKA-----RCIDVTKDPTEVFKA-EAEKLVFYNPRMVFN--RDDKNPVCVELICKNDLDPFGCPAPYLFCAICC-LRRKGVLGVTATDLCALEGKCRTCCKRKYGVQGC-RLCYCKEAGLRVLLGKIVKEACVQEKGIR--PLMGFYHDYYYRLFVKMEDGAKRADRCLE-SLGLYGPPGTGKTCLAIALALKKICCGE-------KIKCEDNALDQIIEACDGDCRYAINFLDPCLKKYICLMPVYLPHCGGRHEHRRFGKARVCIVERLINELMGKKILAYNIVKATFELINARTGQNPLQVLVRAIENCAPREEVTRIMYGGIVYYVAVDVCPQRRVDIVLRNLVDGARQAA-FNNPKPIEEALADELIAAANGD-NR-SFAIRKKEEMERIALCCRRA-HRTMGWGTKGQHRDRGAEGGR-HVGM---HKEKWC-WIVKYGKD-----WYG--KHGFKLLGGGQVKAPLIVKVAVATNKAKEKIEKCGGGKCLEELL------NMPMDDFIKLLPARQRRCLRK----GIKTHVRCLVILPEMVGLKFAVYNGKQFVEFQVVPEMIGHYLGEFCIPIQKVEHGEPGLKATRCCLFMAMKCDNCGAKEAMIICVFG-Y-RGALRRVPYANVGDLVMVCVRKGAPD---VRKQKFKAVVIRQRMPFRRPDGTWICFDDNAVVIVNPD-GT-AKGTEIRGPVAREAAER-WPKVACLARLAADIKNAGVCRVRI--PPEHVDEVAGALTREEIKRLIKDGKIVILCTRGNCRGRVKERRRCRKRKGEGRRTGCKKGRKGART-GKKEEWIVKIRKIRRYLQWLRDHEI-IDTRTYRTLYIKAKGGTFKNLNDVWKPRTKIGQLVKEGKITCIKELYARNMCIAEPEIIDVLL-PNMGELCRYKVLVVMGNYDGYVCIGVGKCKQLRVAIQKAIRDAKMHVIPVRRGCGCWECTCGECHCLPFLVCGKCGCAEVVLRPAPKGTGLVAGGVLKTLLTYAGIKDVWCFCRG-----ETRTTDNFIMAGYRALEFLAKEYYNAEYAGCEICKT-PMGTRVTIYAGRPAIIIGKDGKTIKRLAQILEKYFN-LENPQITVTQP---EKPELNARVMAFRLAVTLEKGYH-FRRAAFMTIRRIMNA-GALGAEVIVCGKITC-ERAKFEKLKEGIVYKTGNNLDVMVDRAIAIATLKMGIYGVEVVITKP---LRTIDLRCILTPEARQRLCNVKLVKPELAECLEDQLIALAQCGRIRVPVTDEELKEIL-----------------------MCVVTKCGKEYFVGTIYQKPPVRCCVRRVRKRKIYCLEV--LGTYMRKICHDMGILLGCGAHMRELRRTRCGIFTEDTV--VTLPMEMAFCGIPKIIVDDETVNCLAYGCPLMAPGVALITWKGEGIPAVTKPEEKPTLNKKL-LWCIVGVVVYLLMCCVPLYGG--TLAQLGIGPIITAGLIMQILVGC--KLLNLNLND-EEDKAKFTEAQKQLIV-ATYLILLLDELIQKG-----LGCGVCLFILAGTTIGLIFLIIYLTCINVQIPPLNFLYVCCIPVIFGIV--WVEVCGLDP-ATQAQNLVDAGIEIPGMRNNPKMIEAVLAKYIYPLAFFCCLIVCVIAVGATLL---GVYG-------TGVGILLAVCIAMQYYCLLAYERCIEMYPLVKRKLLLIGN---FVLTCGKTCYIDLRRFPCYPP--M--GYVRVERKGTDKL--VEG-EVT---GRKVLVVDDVATTGGCLERACAEIVRCGGIFAARKLKLRRLKFRWCQRKFKTRVL-QLKKRFDPLQGA------PMARGVVLEKVGIECRQPNCAVRKVRVQLVKNGRVVTAFVPGDGGVNFIDEHDEVIIAGIGGTLG-RCMGDLPGVRYKVIM--VNGVCLDCLYKGK----KQKPVRLVPLENYL-----SAGVHIGTHTC--TRYMER--FIYRVRP-EGLYVLDVRKIDERLRVAAKFLCRF--QPQCILAVACRPYAFTPVQKFAEVVGARAVVGRMVPGMLTNPYLEDFIE--------PEVLLVCDPRTDTQAIKEAADMGIPVVAFCDTDAKVDYVDLVIPCNNKGRKCLALLYWALAR-QI---LRERKMVVMVRTDINMGKGKIAAQVAHAWLHEGQPKVVVKVCCLEDLLCRVDKARCQGLPTTVICDAGRTQVEPGTVTCAGIGPGPDDLIDKITGDLKLKYIVVTGGVLCCVGKGTVCACLGLILKNMGYNVCIIKVDPYINVDAGTMNPYMHGEVFVTED--------G-----AETDLDLGHYERFLNINTCKHNNITAGKVYFEVIRKEREGKYMGQTVQIIPHVTDEIKAMVDIVIVEVGGTVGDIEGLPFLEAMRELRLEEEEHNVIFVHVALVEYLCVTGELKTKPLQHCVQELRRIGIQPDIVIARCIIELDEDTKRKIALFTNVRPEYIFCCYDVETAYEVPLILQRQGLKDCYLCIKEAIYHEGIIVLPGFGCRGTEGKIKAINYARVNNVPFLGICFGLQLAVVEFARNVVGLQGAHCTEIDPNAPHPVQKKV----TQFGGTMRLGAQRICLVRGTLAHCIY-GKDVIYERHRHRYEVNPC-YVDLLQKHG-----LTIC----GIC-DNG-LVEMIEL--KD--HRFFIATQAHPEFKCRPLNPAPLFRGFTQCVELIIAFKDVDMKR-GDIKLREAIVLPKPPC-KPRNVLVVPCLEQMECAKRAEPNVILCKEELQKLQGAKRAVKKLACKNQWFLIAQDCMCLAGRIL-GPCLGPRGKFPTLVKTKDQPQTQTFVGTEDQPCGDLAENVFAVLNCIEGKI-KGPA--YIKAIYVKTCMGMGDPRKC-RRKWEG--PGMPWLCQALKCEQKIMGDYGLR---NKKEIWLARTIVTGY-RH--MARCLLYKLGLL--KCEQCTIDDILGLEEECLLERRLQTIVHRKGLARTIYQARQLIVHGHIAVGGRKITCPGYIVKRDEEDCIIKECICTEKCVRLLECNNTLVLVVDREDNKATIKCEVEKAFGVKVEKVNVKKAYVKLAPEY--KACEIAQKLGVLDLCGNKVKDVQL-PLIFCYPVRKDLIRRAFHCCFTQGLQPKGRDPMAGKRTTA------KCFGI--NLGLARVP-R--IRGAG-----E-GALAPNTAGGRLAFPPCPRERVKEDINEKEKRLAVICALACTTIKEIVTNRGHRFTG--DL--PLVVVDDLGG-IKKTAELEEILIKLGLEQELKRACYK--RIRAGKGKMRGRKYKRTVGPLLVNLPGVDVVCAKDVCVIHLAPGGHAGRLVIYTECAVKYECHGERFEILVKPKEAMEIR--EGK-S-VCLCDAVVCDTIYKDVKKGLKACPCCLKKVFGTTDFETICREIILKGEIPITAEQRKEMLEAKRKQIIDFIHRNAVDPK-TNLPIPPARLEMALEQARVQIDINKEVEAQALQIIHELTRIIPIKIARALLEVKVPQRYCGKAKQQLCCLG--SVKKTVWLDDGTLVAEI-EIPAGAQQDVIDKLNCITKGVCKIRNGTVIDHIPAGRA--------LAVLKILGIKG-IEGYR--IALVMNAECCKMG-R-KDILKIEDREIEEKEAELITLIAPEATINIIKDYEVVGKRKQEIPQEVVGL--LRCTNPCCITNNDV-EA-ITRFRTL-KRR-PLQLACEYCTNIEKRKLIQFLNKQ----DKPLWEAVAKELDVPCRKVR--TINLYKIDKYTKEG-----DIVVVPGKVLGVGNICHK-VTVFALDFCKCALNKIRCAGGKA--LPLCQGVE--EIKGKVNVRLPVRCFTCGCLIADKWDAFCTRV--RAGE---DP-----GKVLDDLNVKRLCCRRCLLTHMKEGCYIVI------DGEPCRVVEVTKAKTGKHGCAKANIIAVCIFTGAKKTLMAPVDCTVEVPIIEKRMGQVQIMDLETYETDAEVEYWEV-MGRKKIKYIIKLTFEVDGCVDV-----IGAFGQTENLFGQEF----DLRELQDKGRLGRIA---SMVECVEK--------VGPYNAKFELKEIEDVRAEKLKKIIERAVYTDPNLIIVEGRAD------IINLLR--YGYKNTVAGACGKIPQCVVELCKNKKMV-IAFLDGD--------HGGDM------ILKDLINANVKID---YVARAPVGR-EVEELTGKE----IAKCLELAACK--NVKLIIGVRIG-GI-NKKPMRNVRIAKVTVNIGLGEC---GERLQKAYQLVEELT-GAKPVYTKAKKCIKEFDVRKGAPIGVMVTLRDEKAEEFL-KRVLA--AV---NYK-IKACCFDKHGNVCFGIAEHVVIPGTRYDPEVGIFGRIVITRPPELTATRP-VARKKLEDYILIAGCPGMGKTTFAQALAEYYMKM-GK-IVKTIECPRDMHLPC---DITQYCKNYA------EIGELHDIL--------LLCRPDYTVYDEMRNDEDFRLYIDLRLAGI-GMIGVVHATTAIDAIHRFLNRVDLGTVPGI---LDTVLFINKGTVEKVYCLEMTVKVPEGLRE--ADLAR-------PV-VQIKDF--LNDRVEY-EGRDLRKITGG-KKNVCRG-KRKFEIGCQPTETKVY--SED-IREKARVLGGNAKVRLTYAAYANVINLCDGTAKKVKILEVIECCANREYARRGIIVKGCIIRTEIGKALVTCRPGQHGVINAILAGEIACRARDMGARMIKPGVKVIDVCETVEKAII-EAGAKPA------FP--CNLCINHEAAHYCPVIGDEKVIPEGAIVKLDIGAHIEGYITDTAVTLAEAAKDALKCAICNFKMGACLCDIGRVIEKTIKGYGFKPIRNLGGHLIRRYELHAGIF-VPNGNTYAIEPFAT--DGGGEVVEGKDVTILLEVRKGMVCQFEHTVYVDEKGTLVLTCK-PDKCC-IECVRFCPVYEETCIG--CNICVKKCPFEAICIVNVPDNFCKE-IIHRYGTNGFELFGLPI-LKCGYVIGLLGKNGAGKTTILKILCGEIIPNKIQ-----YVEY---ACRLL--KGE-VCQLLRKVDER---G-KLDEIRELLFMNCIWNKEICTLCGGELQKTLIAAALAREANVYAIDEPCCYLDVRERINVAKGIRELTK-----GKYVVTVDHDLIVLDYIADFVCIIYGEC--GVYGKVCKTYCTRVGINNFLNG----YLPAENMRVMFCLNTEQGF-AREGEVIGIVGPNGIGKTTFIRILVG--EIEPDC------GY-------KPQRI-VPD---YEGTVREYLLCGGELQKLYVAGALAKEAHIYLLDEPCCYLDVEERYVVAKAIKRITRERKCVCFVVDH--------D
Methanobrevibacter_smithii_ATCC_35061                   GAE-VAMTGCNPLCT-----HDGWRDQDDEEYYQTINMVLD-----HKPDVIIDDGADMIMVLHGACEETTTGVHRLEAMHKDGALKFPVVAVNDAYTKYLFDNRYGTGQCCFDAIMGTTNMLIAGKCVVVCGYGW-CGRGIALRAQGLGAN-VIVTEPIRALEARMDGYRVM-KIRDADLIITVTGNINIIHGDDFKYMKDGCMLCNCGHFNVEINRRDLEAQ-STCVREVREC-IEM--------FTMKD-GRKIYLLADGRLVNLCAARGQGHPAEIMDMCFAVQVTKAPDDIDYEVANLKLKAMDIEIDTLCDRQKEYMCCWDIGGLKDEVKKVREMIE-IPLKRPELFDKLGIAPPKGVLMHGPPGTGKTLLAKAVACEC-----DAHFIAINGPEIMCKYVGGCEENLREYFEEAEENAP------SIIFIDELDAIAPKREDTQGETERRTVAQLLTLMDGLKCRG------QVVVIGATNRPDCLDQALRRPGRFDREIEIGVPDCEEREEILGADLECLCKEAAMRVVRGVPGTGKTLLAKA---VACECEANFICIKGP--ELLCKWVDEIDCIACTRCANDCDCGVTKRVVNQLLTEMDG--LEELEDVAIIAATNRPDILDAGLMRPGRFDRGIANIYCCYNNTIITVTDITGAETICQWCGGKVVRADRQQACPFAAMAAATRIADDAKEKGFVGLHIRVRAPGGN-GHRCPGPGAQATIRALARAGIKIGKIEDITPIPHDGTGRPGGKRGRRGITGRFGARYGRKAKRCVKMIEENMKKNHVCPRCDR-PYVKRQAAGIWKCRKCGAVFTGGAYVPVDMGAIRFVCNGADIMCPGIVAADENINPEDIVGKAIETKHYVGDYKYIRDAWKNPDE-SYVRELMWERAPKWRRQCAVQRIERPTRLDRARCLGYRAKKGFVLVRTRVRRGGRRKCRFIGGRKPKRMGVNKITQ-AKCIQRIAEERVAKKYPNLEVLNCYWVWADGKYKYYEVILVDPQCPCIVNDEKINWICCKKHTNRALRGLTCAGTKGRGLVTDIVHDPARTAPIAEVKFE---NGEKKFILAPECIQIDDEIGICAPIKFGNTLPLAEIPEGTPIYDIENTPGDGGRFVRCCGTYALPCGELKYLNPRCRACIGVVAGGGRKEKPFLKAGNRWHAYKAKGKKFMTVRGVAMNAVDHPHGGGNRQH-PG--RPTTVCR-HAPPGRKVGCIAAKRNIGICAHIDHGKTTLCDNLLAGAGMICE--ELAGDQRFLDFDEQEQARGITIDAANVCMVHNYKDEE----YLINLIDTPGHVDFGGDVTRAMRAVDGAVVVVCAVEGIMPQTETVLRQALKENVKPVLFINKVDRLINELKLEPEELQKRFINIYMEANKLILGMVVEHLPCPKVCQEYRVPNIWEGDIECPAGQGMITTCPDGPLAVMVTNVCVDKHAG-EIATGRVYGGCIEKGTEVYLVGC-HCKCRVQQVGVYFGPERVNTDAVPAGNIVYVAGAKGAIAGETEGLDHICEPVVTVAVEAKNTKDLPKLIEVLRQVAKEDPTIKVEINEETGEHLVCGMGELHLEVICY-RI-KDKGVEIQTCEPIVVYRETVCQLC-PQVEGK------SPNKHNRFYITVEPGIQYLDEVKELLIEGFECALNDGPLAKEIAMGLKFKLHDAKLHEDAVHRGPAQVLPAIRNAIYACMMCAGPTLLEPMQKVFINTPQDYMGPCTREIQNRRGQIVDMGQEGDM-ATIECKVPVAEMFG-FAGDIRCAAEGRCLWCTEMCGFERLPDPLADALTNIRNNELQVKDCCVICPACKLIGEVLCTMQKENYIGNFEYID-DGQ-FKVELEGN---INKCG-------VIKPRHAVKKDEFEK---FEK-RYLP--AKNFGILIVTTPEGIMTHYEAKERGIGGRLLAYMY------------------------------------------------------------------LKETIFENLNLVRVYLKPQGRKADMNDPFRH-----AKIGPDHVLED----EDMTTVFDVPADLLIKKVAEEFKNN-DKINCPAWCNFVKTGVHKERKPEDV-D-WWYTRCACIIRRVYMDG-PVGVMCLRTFYGGKKD--RG--VTPEVFRKGCGAIVRNALHQLEDAGYVEKVVG---GRVVTPAGRCFLDKICDGEGCVLGRLACVTCGEE-VVILNAEKIMITGNKDWAYAKYK-QRVDRACICNPRDLGPKYPRRPDDIFRRTVRGMLPY-KKCKGGCATPGPPLGPALGPFGINMMQVVEEINNKCADFA--GMKVP-VKVCI-DRDTKEFEIEIGTPPTTCLIMEELGIEK------ACHEPGA-DIVADLPIDKALKIARMKFDCLLANDYKAGVKEVMGTCVCMGLCVDGKDPREAQKDVDAGKVGMTHALVTDCDKNCPTNGMDVFTPVTVLEVPPVVVMGIRA-YEKTCRG--LKVITEGNEVKACDILNEGQFVDAIATTKGKGFQGVVKRWGIRIQY-GKAVRAGKGRH-VGCIGP-WTPCRTMWTVAQAGQMGYHKRTEFNGFVKYGLVKNDYVLVKGCLPGPCKRLVILRQPIRG-GIHPRIAAEHHCFCQGPGLGPALRIVATCARTLALCLNKPIIGVNHCIGHVEVGKLDT-----GAVNP-VTLYVCGGNCQVICHEC-GRYRI-FGETLDIAAGNCLDHFGRETGLGHP----GGPVIEKLAK------KG---SYVDLPYVVKG-----MDFCFCGLLCETAFCMLVEVTERAGGVCANCRLREMLKVM-AEEHGAKFCMPEMKLCGDNGVMIAWLGLIMHNQFRIKLTGTDPEKLAYVCDQLKKIAERTGVDLCGPIPLPTKKLVVPTRKCPDGEGKACWEKWELRIHKRLVGI-GADERAMRQVMKVNV---PDNVCIEIINFGLMCPEDIREMCVVKIETPDTYDEDGY-PIENGLMDPHL-GVIDPCLKCRCCGYRGGEC---QGHFGCIELARPVIHVGFGD----IIHKILRCTCNECPH-------CRERLERICD--EDR----PEWLVLTVLPVPPVTVRPCITLDTGERCEDDLTHKLVDILRINQRLIENMEAGAPQLIVEDLWELLQYHVTTYFDNEACGV------PPARHR-SGRPLKTLAQRLKGKEGRFRCNLCGKRVNFCARTVICPDPNICINEVGVPEMIAKEVTVPAYVNDWNMDEMRTYIENGPNVHP-------GANYIERHLKDGDMVLFNRQPCLHRMCMMAHEVRVLPYKTFRLNLCVCPYNADFDGDEMNMHVFQTDECRAEAKCLMRV-QEHILCPRFGGPII--GAIHDHICGAYLLTGKELFCLLLPDGYENDYLEALPGRCLEETLEMKINHCVVMARTGARACMLNLTQITCCVGQQCVR--------GGRIHRGRTLPHFRKNEL-GAKAKGFVHCCYKKGLDPIEFFFHAMGGREGLVDTAIRTAQCGYMQRRLVNALQDMGE--VVATLKIMPECPDVDLEALE-PIAFGLVALNLIFIIEDGE-GGTECTEEAMAKLADVVKGPNGEDCRKFTYP-NVDITEVENN----VTTKAHICNMITGVTDGFEYHMKIVFAHFPMTVKVNKDV--VVIDNFLGERHPRTAKVV-G-SAKVVV---KG-DE-VTITGINKEHVGQTMANLGIDEAGRGCVLGPLVIAGVDCKRLTPNRRTILCRKLDDNYIEVCAACIIAKQERDAHIAEINKDYIKMGGRARRPLIIVK---DGGFIEYLDAEEGICAGIIPFCDHNCCPRNTMEAGMTKQGLYVCN-YALRTDTRAHLLHH-PQTPVKTRIIDCTN--YDKRPC--------GQNFVVAYEGYNMEDAMVINKGCLERGLARCCFFRAYDTAEKRYPGGD-KFEVP--DKNIK--GYRCEDAYRHLDD-DGVVNPECYVRFL--EEIDEFG-TV--AEKRRETCRHGEKGIVDAVLAKIRVRDTRGDKFACRHGQKGVLGLILCPEDVPFTENPHAIPCRMGQVLEMVAG-------KGCECLYNGVTGERIEAEIFVGVAYYQKLHHMTTDKVYARCRGPVQVLTRQPTEGRAREGGLRFGEMERDCLIAHGAALTLKERLLDECDKYEAIVCEN--CGYAFKLLLDELKCLCIFPKLDAGLFIKALKGFPGTYGKVIGEIAVEEKGDL-GFAFDPIFYVPA------EG---KTFGELTTEEKKTAIARGTVQEGTGKVRINELYCP-ELANLKLQEPDINIHVVGGGVMGQAEAARMVIAKLKDKFIHYDRTMLVGDPRRCEPKK--YGGPGARARKQKCYRTKNLTPGICVYGERIWNPRRCKLLYLGACTGTTVCHICDIV-TDGRIYAVEFCPTVAQPTQCQLFMKNVIGA--LMIKA-----RCIDVVQKPKKIFKE-EERKLVFYNPHMELN--RDDICETANEYERHNDIDPFGTPCPFLDCAGYC-SRRNCLLCVTATDTCALCGTYKEPCIRKYNAKPY-KCEYCHETGIRILAGFVALTLAKYCKCIE--VKLCHCTEHYMRLYIEVKKGCKKCDECLK-NIGLVGPPGIGKTTLAQAIALKQIAINE-------GIKANPAALKELAKKCNGDMRCAINTFDLGLVKYICLDETLVPHTCGRHVKRQFAKCKVCIIERLMNKIMGKKNKAYNIVKDALDIINKRTKKNPVQVLVTAVENTCPREETTRIKYGGIGYQVAVDICPQRRVDLCLGFLTRGTLQCA-FKNRKCVAECLADELILACEED-SR-SFALQKKEEKERVAKAAHRG-SRCNGGGCTKKRRGAGNKGGRGNAGA---SKQHWT-WTAKFDPD-----HYG--KHGFKVLAKGKITKCFIICAPQFCACAIEKIEEMGGGYTLEELQ------DMCLEEVMELFPARQRRCLKR----GIRTHCRDMIVLPEMVGTTFGIYNGQNFVEVTIEPEMIGCYFGEFAPTRQKVQHGDPGMGATRCCMFVPLKVDNTGAREIQIICVKG-F-KGVRRRLDVAGVGDLVVACVKKGTAD---MRREVVNAVVIRQKKEYMRADGLRVKFEDNAAVIITPE-GI-LKGCEVRGPVAKEAADR-WPCVGCAARLAACILKVGLNRVWI--DPERMEEVCMAITREGVKQLINNGAIKAKPQKGICCYRCKKLAEQKK-KGKRKGRGCVKGAKKARN-PKKQEWMTTIRALRKDLKEMRDANE-IDATTYRKLYKMAKGGAFRCKCYMWEPKTKMGKLVKEGTITDIDEIFEKGLPIMELEIVDALV-PDLGRKVNFRVIVAVGNKNGYVGLGQGKAKEVGPAIRKAVDNAKYNLIKVRRGCGDWGCVCGKEHTVPFKVQGKACCVCVCLMPAPAGVGLVVGDVGKTILNLAGIKDVWCQCFG-----QTQTTVNFANAIFDALEYLEKELERAGYGGMDVQIT-PLGTMVVVYAERPGMVIGRGGKNVRAITNTLKNDFG-LDNPQIEVKEV---SVPELNPKIMAYKIANMLQRGMH-FRRVAYCTIRRIMGA-GAQGVEVTICGKIRG-SRCAVAKFVEGYIKKCGEPCIRLVEEGFATVQLKPGVLGIYVRIMPP--ETVLPDIAQILTTEARCRLANLKLTKPELVNQIEIQLIQCAQAGCLRGKVTDEQLKVLLHGGTLDPKVTGVLPVGLGDATRAIQLLLTAPKEYFTGKIFQLPPVKCAVRELRCRNVYYCTI--YGTYVRTYCHNIGEAIGVGAHMAELRRTQVGCFTEDNHL-STLPMERAADYLPKVVIKDCAVDAICHGANLACGGVAIETLKGELVPEVKCPVHHEDFNEKL-KWTALILVLYFILTEIPLYGG--SILTLGIGPIVTACIVLQLLVGC--KLLDLDLCC-PEDKCQYQATQKQLVI-GAILIIYLDEVICKG-----FGCGIGLFIAAGVTAAVFFVVVYGECMRVEIPPLKFVYACNMPVIFCYL--WVEICGLNA-KKICEQLYKCGIQIPGFRCCKRQLYKILKKYIPALTIICGLYVGIIAFCADLT---GALG-------GGTGVLLTVGIIHKIYEEMAEEQLMCANPLKENGVFLKGD---FTLCCGKKCYINMKKAITDPP--L--LMIRKEKKGTCKL--IEG-ELN--EGDDVIVVEDVTTTGGCLLKAIKAIQDNGGLFAAKKLKKNRQNFKWKDVDYKRKAL-RLDVKADPLEGA------PQARGIVIEKVGIEAKQPNCAIRKVRVQLIKNGKQLTAFAPGDGAIGFIDEHDEVMIEGIGGPCG-RCMGDIPGVRWKVCK--VNNVALCEMVCGK----IEKPVRLIELDNYL-----AAGLHIGTQQK--TCDMEK--YIFRVRC-DGLYVLDIQKTDERIRQIAKLLARY--DPEDILVVATRQYGQAPVKKFGEVTGAKTIPGRFIPGTLTNPTYAKFIE--------PKIIVVTDPRCDAQAVLECKQNGIPVIALCDTENLLCFVDIAIPVNNKGRKAIALVYWLLAR-QI---LRERKQVMVVRRDLKMGKGKIAAQCCHGWECDGYAKVVCKVDCLEELLDLKKEADKNNVCNYLVVDAGRTQLPTCTTTVLGIGPDEDEIMDKITGDLKLKYIIITGGVVCCIGKGITCACMGRILRCYGLKVAAIKIDPYLNWDCGTLNPYQHGEVFVTND--------G-----METDLDLGHYERFLDVELPGLCNITTGKVYKCVICKEREGKFLGACVQVIPHITNEIKEMIDVVLIELGGTVGDIECQPFLEALRQLRNEEGHDNVMFVHVTFIPYLNAAGEFKTKPTQHCTKELRCMGINPDVIVCRCQEPIDDALEGKIAHFCDVDQKAVVNTPDAGTIYEVPLVLEENNLEDAYICIRECLQHHGILIPGGFGERGFEGKLDAVDYAIEHNVPLFGICLGMHCIVTQFARRN-GYPEANCCEFDCENPHPVQKKV----KNMGGTMRLGCYDCKLVKGTKTYEAY-NVEDIAERHRHRFEFNND-YRKDLEDKG-----LVIC----GVC-PDDFLVEIVEL--PN--HPWAVGCQFHPEFKCRPNRPHPLFRNFTQCVDMIVNIRDLDVKK-PENRFNEEVTLPNGRG-KEVKIGVIADGELIVQAKDAGVALVINKADLEELGKDRKAAKKAANCVDFFIAQADMMPLVGRFL-GPILGPRNKMPVKVGIKQQPAIQIIVGCQDMCDEDLAENIETVLTVLDRHLDKGRN--QIKCMFIKTTMGMGQPRKC-RKKYNT--PPHPWNAERIKNENKLMTKYGLK---NKKEIWKADTLVRRY-SR--EARYLLARTGVL---PEGAALEEVLNLTVEDILRRRLQTIVYKKGLARTPKEARMFVVHGHITLNGKKINCPCYVVLKGQEDEIIIKPHVTEKTMNLIDKNNEITFVVKRDANKGQIKRAFEELYEEKVARVTTKVAFIKLVEEE--MAEELAVKIGVYCMEGEVKEEIEL-PAIFNEEYRPDLIKRAVICAQTARVQPWGNDPEAGKRTCA------KGWGC--GRGTARVP-R--IKNGC-----K-AAFVPMAVGGRRAHPTRAEKNHHEKINIKERRFAIRCAVAATANKELVENRGHRLGDLEQV--PIIVEDDICC-VKTTKQTREIFQNLGVYDDITRAKEGK-RIRAGRGKTRGRKYKKVKGPLLVNHAGVDVVTVENLNAELLAPGTHPGRLTIFTKCAAKYEYCGEHFEILVDPDLAAEFRNPDGQ-D-VAIEDLLAVEEIFKDCKKGDKACEEAMLKIFETTDPIGVCKVILEKGHVQLTAEQKRQMQEDKRRLVINKICREAINPQ-SGLPHPAQRIENAVNEAKVKFDPFVCVDQQVQTALKAIKPLIPIRFEKVKVAVRLPGCCAGGAYCAIHHFG--EILNEEWQQDGCWIGIV-EMPGGLQDDFAAKMAEICCGIRAIENGTVIDHITANKC--------LHILKILGLPD-SETKN--VTVAMNVCCKEIG-R-KDIVKIENRELNHEELDQIALIAPKACVNIIRDYKPVKKDKIILPNTITGI--IKCTNCKCITNYAN-EPIAPKFNVI-NNH-PPVVRCHYCTNPNLIELINKLNKKCKTENAAIWKDVANRLGRCNRRTA--EVNLCDIARYANAD-----ETVLVPGKVLCNGDLTEK-VNVAAFKFCQKAQEKIECAGGEC--VCIDDIME--SNPKGCNIRIPIRCLCCGKPVCAYFDEYNKRL--AAGE---KC-----KDILDDLGLNRYCCRRMLICHLKVGKYIVL------GGEACKITCLTTCCPGKHGAAKARLEAVGIFDNQKRCIVKPVDTKVDIPIIDKRVGQVQLMDMENYDTGIEVDYIVA-LGNMKIKYLIHAQINANGIVDV-----VGAFGQTEGLLCNDL----DLRELQRTGRIGRIA---ACLETINR--------VGPCEAEIHTVKVEDVRAVKREQVVNRAIHTCDAIIVVEGRCD------VLNLLK--YGIKNTVAGVC--VPQCIGNLCKKRTT--TAFVDGD--------RGGEL------ILKELLQI-GDVD---YITRAPKGK-EVEDLEKDE----VLVALDVACLK--GIKRLVAFRCM-NI-VKKPMNEVQICKATVCIGVGEA---GEKLCRAITLLEQMF-DQTPVKTFCKVTNPEFGIRKRQPIACKLTLRGEKADKAI-EMVLE--GI---NKN-IKPTQFDAQGNLCFGIKEHIDIPGMKYNPDIGIFGRICMAKPPEITAVRP-VANVCLDEYILICGCPGAGKCTFVQALAKYYAEDLNK-IVKTMECPRDLQLPA---EITQYAPLEG------SMENTADVL--------LLVRPDYTIYDELRKNCDFNIFADMRMAGV-GMIGVVHATRPIDAIQRICCRVELGIITCV---VDTCIYIEDGDIKEVFETKMTVKVPCGMKE--ADLAR-------PV-IEIRDF--ETGELKN-EGKCTRLPCGA-RNVANRG-KRKAELGRDPAETRVD--EK--RLKKIRTRGGNEKLRLATANKMNLTDPATGKCQVVDVLGVIENCANPNYVRRNIITKGAIVETPEGNAKVTCRPGQDGVLNGILAGKILCQIRKEACKMIKEGTLVLDLVEFVENETI-KQGAGIC------FP--CNVCINEVAAHYTCPLNDETMIYAGDLVKLDLGTEIDGYIADCAITIIEACAAGLDAAICTVRAGVTVGEIGAAVEEAINEYKLNPIANLTGHCLEQYNLHAGIC-VPNGQAVAIEPFAT--DGIGFVNDAPGTYILKEKTGCLVCQKEHTVIVEKEGCTVTTCQ-PKKCN-FVCIDYCPICEELCEG--CGICTNRCPFDAICIINLPEAIGE--PIHRFGQNQFELFGLPC-LTEGCVLGLLGPNGIGKCTIMNILCGTLIPNKPQ-----MVDQ---LPKVV--KGK-VCDLLTNVDER---G-KLDYVCDELDLHNVLDREMKNLCGGELQRVAIAATVLREGDFYYFDEPTCWLDVCQRLNAVKVIRCLAQ-D---GKCVLVIEHDLATLDALCDNIHVLFGEP--GGYGVVCGRKGVRIGINAYING----FLAEENVRIRFKLTADAGE-IFHDEIVTAFGCNGIGKTTFAKMLAG--VEEPTC------GY-------KPQYI-VCD---FEGTVCDFLLCGGELQRLAIAATLCKDAEIYLFDEPTAFLDVEQRLIAARVIRKMVECRNAACLIVDH--------D
Methanocaldococcus_jannaschii_DSM_2661                  GAE-IAITGCNPLCT-----QDAWRGETVEEYYENLNKVLD-----HKPDIVIDDGCDLIFLLHGGCEETTTGIIRLKAMEKEGALKFPVMDVNDAYTKHLFDNRYGTGQCALDGILRATNLLIAGKTVVVAGYGW-CGRGVAMRAKGLGAE-VVVTEPIRALEARMDGFRVM-KMEKADIFITTTGCKDVIRKEHILKMRNGAILANAGHFDNEINKKHLEEL-AKCIKEVRNC-VTE--------YDLGN--KKIYLLGEGRLVNLAC--ADGHPCEVMDMCFANQVYNIPYEQDLMIACLKLKAMGIEIDELTKEQKKYLEDWDVAGHEKVKEKLKTWIE-SYLKG---------ETPKPILLVGPPGCGKTTLAYALANDY-----GFEVIELNACD------KRNCCAIKKVVGHAATCCCIFGKK-FLIVLDEVDGIC-------GKEDAGGVCELIKVIKKAKN--------PIILTAN----DAYAPCIRCLLPYVEVIQLNPVHTNCVYKVLAGDLRCAINDLEALALCEEVARAFEYLCKADRYLGRVMRRQNYCFWKYATTLMTAGVLLTKTKAEREILNKILKKIGEKTHTCCKRARFD--LQMLKLLAKENPCVAADLVDYFEIKEDELKVGIVHIYCCYNNTIIHATDITGAETIARVCGGRVTRNQRDEGCPYAAMQAAFKLAEVLKERGIENIHIKVRAPGGC-GQKNPGPGAQAAIRALARAGLRIGRIEDVTPVPHDGTTPK---KRFKGPTGRFGPRYGLKIRVRVRDVEIKAKKKYKCPVCGF-PKLKRACTCIWVCGKCGAKIAGGAYTPVDIGAIKFLINGADVMAPGIVDADENIKEEDVVGKAIKNLHYVGDYKYIREAWKRPKE-SYVRQLLWERLQQWRREPAVVRIERPTRLDRARALGYKPKQGIIVVRVRVRRGGLRKPRPKNCKKPATLGVNKITM-GKCIQRIAEERAARKYPNMEVLNCYWVGEDGKHKWYEVILVDPYHPAIKADPQLNWLCTGKHRGRAFRGLTCAGKKGRGLIVDILHDPGRCAPVAKVEYE---TGEEGLLVVPEGVKVGDIIGVCAEIKPGNILPLGAIPEGIPVFNIETVPGDGGKLVRAGGCYALPCGHIKALHCMCRATIGVVAGGGRKEKPFVKAGKKYHAMKAKAVKWPRVRGVAMNAVDHPFGGGRHQH-TG--KPTTVCRKKVPPGRKVGHICARRNIGICAHIDHGKTTLCDNLLAGAGMICK--ELAGEQLALDFDEEEAQRGITIFAANVCMVHTYEGNE----YLINLIDTPGHVDFGGDVTRAMRAIDGAIVVVCAVEGVMPQTETVLRQALRERVKPVLFINKVDRLINELKLTPEELQCRFIKIINDINNLILDMVIKHLPCPPEAQKYRIPHLWKGDLNCEAGKAMLNCDPNGPLAGVITKIIVDKHAG-AVCVCRLFCGRIKQGDEVYMVNN-QQKAKIQQVCVFMGPERIPVDCICAGNICALVGLKEACAGETEAITHICEPVITVAIEAKNTKDLPKLIEVLRQVAREDPTVKVEINEETGEHLLCGMGELHIEIITKLKIERDAGIPVEVGQPIVVYRETVTGQC-PVVECK------SPNKHNKLYFVVEPGIVHLDEVKELIIQGFKEAMRNGPLAAEKCQGVKVKLMDAVLHEDAIHRGPAQMIPAARFGIRDAMMQANPVLLEPMQFVYINTPQDFMGAAMREICNRRGQILDMEQEGDM-AIIKAKCPVAEMFG-FAGAIRGATQGRCLWCIEFAGYEKVPDPLANALNHICNCERVGKKVVYIKPACKLIGRVLKVMQDNGYIGEFEFIE-DGI-FKVELIGK---INKCG-------AIKPRFPVKKFGYEK---FEK-RYLP--ARDFGILIVCTTQGVMCHEEAKKRGLGGRLLAYVYGDATAAFVGFPCVGKCTLLNKLTPGII-VGACCGKGRGTEVLC-AVRCADLN-------EYRIHNALKEKIYEKLGFIKIYLKPQGKKPDFDEPFRY-----AQVGLDHKLED----GDMVTVYDVPADKLIQKTAEKLKEMN--IGVPEWVDFVKTGVCRERRPDQD-D-WWYIRCACILRKIYIYG-PVGVCRLRTAYGGRKN--RG--HEPEHFYKGCGNIIRKALQELEKLGLVEKTPE---GRVVTPKGRCFLDNIADAEGAILGRLACEVAGEE-IVIVNAEMVVITGNKDWIIKTYQ-EEREKKNVANPRRFGPKFPRRPDDILRRTIRKMLPY-KKPKGGRATAGPPLGPAIGPLGVNVMQVVKEINEKTKDYE--GMQVP-VKVIV-DTETRKFEIEVGIPPTTALIKKELGIET------AAHEPRH-EVVGNLTLEQVIKIAKMKKDAMLCYTLKNAVKEVLGTCGCMGVTVEGKDPKEVQKEIDAGKAGMCHAFIKEDNPKCPNAGQEVFTPITILEAPPINVCAIRV-YGRNERNY-LTTLTEGKQLNITDVFQEGELVDTIGVTKGKGFQGQVKRWGVKIQF-GKHARKGVGRH-VGCIGP-WQPKMVMWCVPMPGQMGYHQRTEYNGFLHYGVIRNNYVVLKGCVQGPAKRLIVLRRAIRQ-GINPREAADHHAFCQGPGLGPCLRVTATVARTLCLTLKKPIIGVNHCIAHIEIGKLTT-----EAEDP-LTLYVCGGNTQVIAYVC-KKYRV-FGETLDIAVGNCLDQFARYVNLPHP----GGPYIEELAR------KG--KKLVDLPYTVKG-----MDIAFCGLLTEYAFCMLTEITERAGGVAANNRLREMLKAM-CEGQNVDFYVPPKEFCGDNGAMIAWLGLLMHKNGRIKLCCTDHKVLDEICRQIKEIAEKTGVDICGPIPLPTKVLRVVTRKCPDGEGCCTFDRWTMKIHKRLIDI-DADERALRHIMKIRI---PDNVQIEIIMFGLLCPDYIRQMCVAKIVTPDTYDEDGY-PIDGGLMDTRL-GVIDPGLVCKTCGGRIGEC---PGHFGHIELAKPVIHIGFAK----TIYKILKAVCPHCPH-------CREILEKIPD--EDR----PEWMVLTVLPVPPVTVRPCITLETGERCEDDLTHKLVDIIRINNRLEENIEGGAPNLIIEDLWNLLQYHVNTYFDNEAPGI------PPAKHR-SGRPLKTLAQRLKGKEGRFRYNLAGKRVNFCCRTVICPDPCLCINEVGVPEVVAKELTVPEKVTKYNIERIRQLLRNGCEKHP-------GVNYVERHLMDGDIVLYNRQPCLHRMCIMAHRVRVLPYRTFRHNLCVCPYNADFDGDEMNLHVPQCEEARAEAEALMLV-EKHILCPRFGGPII--GAIHDFICGAYLLTGKKIFCKALPDGYERGELELLPGLNLEECREAYINHAVIMAVTGARGNILNLTQMAACLGQQCVR--------GKRIFRGRVLPHFEKGDL-GARCHGFVRCCYKKGLCPTEFFFHAMGGREGLVDQAVRTAQCGYMQRRLINALQDMAT--VLAKIKIMPTCPEVNKEKLE-PLAFGLYAIYTVIEMEERE-GGTEPIENALAEIDEVVKCGGKELRRRFEHP-KIVIKKEGDE----ITIRAHINNMIKGVTEGFTYKLKIRYAHFPMKVCVKGNE--VIIENFLGEKHPRRARIM-E-GVTVKI---SG-ED-VIVTGIDKEKVGQTAANIGIDEAGRGPVLGPMVVCAFDCKELTKNKRAYLKKLLDAKYPVVCAACIIAKAERDEIIDYYKK---IYGGRIVRPLIVVE---NGGVIEYLDAEEGIGAGVAPYPEHNCAPRITMAAAMGKQGIPMCN-IKWRLDTRGHYLHY-PQVPVRTKHQEILG--FDKRPA--------GQNFVVAYEGYNMEDAIVFNKCAIDRGLGRCTFFRTYDACERRYPGGD-RFEIP--DKGVR--GYRCEECYRYLEE-DGIVAVECHVRFL--EEHEITI-QV--KPQRRDCCRHGEEGYIDKVLVKVKVRDLRGDKFACRHGQKGVMGLTVPQEDLPFTENPHAIPCRMGQLLEMLGG-------KGKEVMYDGKTGKKFEVEIYIGIAYYQKLHHLVAGKIHARCRGPVQVLTRQPTEGRAREGGLRFGEMERDVLIGHGAAMLLKERLMDECDPYDICICCK--CGYAFKLLLDELKCMCILPRIDCGFFVEALNGFPGTYGIVKGRVCEEIRCKGYGFAYDCIF-IP-------EEEE-RTFAEMTTEEKKRAIARAVAREGKGRIRINELIEP-KYKRMKLMEPDIDVTVKGGGVMGQMDAARTAIGKLRDKFLAYDRTLLVCDARRTEPHKPCRCTKGPRAKRQKCYRTKCIVKGKKVYDERIWNPNKCKLLYLGACAGTTPCHVADIA-DKGIVYAIEYAPRVAQPNQAEILIKNGYGM--IAIKA-----RCIDVTKDPKEIFKE-QKEILVFYNPRMKTC--RDDINPKAYEKIINNDIDPFGCPAPYVEQAIRALVTRNGLLCLTATDTAALCGRCKKCCLRKYLAYPL-FGRDCHEFALRVLVGYVMRMATKYELALK--PVFCHATDHYVRVYLVTDRGAKRADKVFE-MLGLVGPPGCGKTTLAYALALKKIAEKE-------GLDVDDKTLKMIAQHCAGDLRCAINDLDPGLRNYINLTPIYVPHTAGRYTKRQFEKAKMNIVERLVNKVMGKKLKALKIVENAFEIIEKRTKQNPIQVLVDAIENAGPREDTTRICYGGIVYLQCVDCCCLRRIDVALRNIALGAYMAA-HKCKKPIEEALAEEIIAAARGDMQK-SYAVRKKEETERVAQCARRG-SRTCGGGCHKKRRGAGNKGGRGMAGG---HKHKWT-WIIKYCPD-----YFG--KYGFKVLGKGKVTIPMIVKAVEVCEKAREKIEAVGGGYTLEELQ------QMPLREFAKLLPARQRRTLLR----GIRTHCRDFVITPDMVGLTFGVYNGKEFVEVKVTPEMIGHYLGEFCLTRKPVQHGAPGMGATRCCMFVPIKADNTGAKEVEIIAVRN-Y-KGVARRLPTARVGDMVIVTVKKGTPE---MRKQVLPAVVIRQRKEIRRPDGTRVKFADNAVVIVTPD-GN-PKGCDIKGPVAKEAAER-WPGIARIARMAAEILKCGIERVWI--DPTQLDRVKMAMCKDDIRALIKEGVIKKKQKKGICCARVKKLKEQRK-KGRRRGPGCRRGAAGART-PPKERWMATIRALRKTLKQLRDCGK-IDRKVYRKLYRMAKGGAFRCRCHLWEPKTTIGRMVKEGQITDIDYILDNNLPILEPEIVDALL-PDLGRRARFRATVVVGNRNGYVGVGKGKAKEVGPAIRKAIAQAKKNIIRVKRGCGCWECGCGTPHCIPYKGYGKCGCTAIEILPAPKGVGLVAGDVAKAVLGLAGIKDVWTKTFG-----ETRTTYNFAMATFEALEYFKKELCKAGYCHCDIRKT-PIGTKIIIYAEKPGFVIGRRGCRIRELTETLAKEFG-VEKPQIDVKPV---ENPDLDAQVVAQKVAQCLERGLH-FRRVGHTAVRRVMNA-GAKGVIVIICGKLTG-ERARTEKFMAGYMKHCGEPAEELVDKGRAIAKTKPGVIGVTVKIMRP--DVLLPDLRKILTPEARERLERIRLARPEFAEAVEVQLIQLAQLGRLPIPLCDEDFKALLHGGTLDPKVTGVLPVALERATKTIPMWHIPPKEYFTGRIYQRPPLKAAVRRLRIRKIHELEL--LGTYIRKLCEDIGEALGTCAHMQELRRTKCGCFEEKDA--VYLPMEYGLRHLKKVVVKDCAVDAICHGADVYVRGVLVETLKGEAVPEVELPVKEITFKEKL-KWTGIVLVLYFIMGCIDVYTG--TLITLGIGPIVTAGIIMQLLVGC--GIIQMDLCI-PENRALFQGCQKQIAF-GCIILIYLDEIVCKG-----IGCGIGLFIAAGVTIIVFLMVVYAECMRVEIPPIKFVYVCNIPVIFGIF--WVETTGLDP-KCMAKRIGCLGMAIKGFRKCEKAIEHRLKRYIPPLTVMCCAFVGFLATIANFI---GALG-------GGTGVLLTVCIVYRMYEQLLREKVCELHPLKEVGCIRFGE---FILACGKKCYIDIKKATTNPP--L--LIVRKKPKGTKNK--IEG-ELK--EGDKVVIVEDVTTTGGCVLKAVKEIRENGGEFAGRKLRLKRKWCRWHDYNYVRRVL-KLKEKYDPLEGA------PMARGIVIEKVGLEAKQPNCAIRKVRVQLIKNGRVVTAFCPGNHAINFIDEHDEVIIEGIGGPKGPRAKGDIPGVKYKVIM--VGRNCLRELVRGR----QEKIKRLVPLDTYL-----ACGIHIGTQQK--TKDMEK--FIYRVRC-DGLYVLDVRKTDERLRIAAKFLARY--EPEDILAVCRRIYTMGPLEEFGKYTGIRTVAGRFVPGTLTNPAYKGFME--------PEVVFICDPRVDRQALKEATEIGVPIVGLCDTEHLTCFIDLVIPTNNKGKKAVALIYYLLTR-EY---LKNRKMVVVIRNDLGMGKGKMVAQGGHAWLREGQKKVVVKVNCEKELIDIYNKARCEGLPCCIIRDAGHTQLEPGTLTAVAIGPEKDEKIDKITGHLKLKFIFITGGVICCLGKGITAACLGRLLKARGFKVNMIKIDPYLQIDAGTMCPYEHGEVFVTED--------G-----GECDLDLGHYERFIDENLTKNNNITTGKIYWCVLTKERKGEYLGKTVQVIPHITNEIKDWIDITIVEIGGTVGDIECLPFLEAIRQFKKDVGKENVLYIHVCLLPYIRAAGELKTKPTQHCVKELRCIGIQPDILICRTEMPICDKIREKLALFCDVDKEAVIEARDARTIYEVPLNLEKEGLKDAYLCITEALIHDGILVPGGFGDRGVEGKINAIKYARENDIPFLGICMGMQCAVIEFARNVCGLEGANCTEFDENTKYPVQKEI----DAKGGTMRLGAYPAILMEGTLAYKLY-GRKEVYERHRHRYEVNPE-YHEILENHG-----LTIC----GKC-PDGRLAEFIEI--SK--NRYFIATQAHPEFKCRPNKPHPLFRNFTQCFEFIATLKEIDMRK-PENRIKTEVVLPHGRG-KEAKIAVIGTGDLAKQAEELGLT-VIRKEEIEELGKNKRKLRKIAKAHDFFIAQADLMPLIGRYM-GVILGPRGKMPVVINTRDKPYFQVLVGNEKMTDEQIVDNIEAVLNVVAKKYEKGLY--HIKDAYVKLTMGMGDPRRRFKKTYET--PNHPWIKERIEREKELCRKYGLR---RKREVWKAETILRKY-RR--QARRLLKKYGIL--KIENPTLDDVLCLTVEDILERRLQTLVFRKGLARTPRQARQLIVHGHIAVNGRVVTAPCYMVTVEEEDKIIKAPVVTEKTVRMIEEENKLVFYVDRRATKQDIKRAMKELFDVEVEKVNTKKAYVKLKEGY--DACKIAACLGVYNLNGEAVKEIDL-PAVFEEEYRPDLIKRAFLCAFTARLQPKGCDPLAGLRTCA------KNIGK--GHGRARVD-R--VPQGW-------AARVPQAVGGRRAHPPKVEKILWERVNKKERIKAIKCAIAATANPELVKERGHVFET-ENL--PIIVECCFEE-LQKTKDVFAVFEKLGICDDVIRAKNGI-KIRAGKGKMRGRKYKKPRCILVVNLPGVDVITAKDLGIIHLAPGGVAGRLTVWTECAARYTCHGEKFEILVDPYLAAKLK--EGQ-N-VDFDELLAIEVVFRDACKGEKAPEELLCKIFGTTDVKEIAKKIILKGQVQLTAKQREEIREQKKRQIITIICRNTINPQ-TDTPHPPHRIEKAMEELRINIDIYKCAEEQVPEIVKKLKKVLPIRFEKRDIAVKIPAEFACKAYNALYQFG--AVKQEEWQPDGCLIVLI-EIPCGIEAEFYAHLNKITKGVKKITNGTVIDHIDAGKA--------LMVFKVLNV---PKETC--VMIAINVPCKKKG-K-KDILKIEGIELKKEDVDKICLICPDVTINIIRNGKVVEKLKPQIPDEIEGT--LKCTNPNCITN--K-EKVRGKFKIE-SKN-PLKIRCYYCTNPRLVKLIEILKQECYKNQAKIWKDIARRLAKPRRRRA--EVNLCKINRYTKEG-----DVVLVPGKVLGAGKLEHK-VVVAAFAFCETAKKLIKEAGGEA--ITIEELIK--RNPKGCNVKIPIRCFCCGNVIAEVFEEYKERI--LKGE---NP-----KDVLDDLGIKKYCCRRMFICYLKVGQYVMI------DGVPCEIVDICVCKPGKHGGAKARVVGIGIFEKVKKEFVAPTCCKVEVPIIDRRKGQVQIMDLQTYETGGEVEYIEA-VGQYKIKYIIYAELIADGYVDV-----IGAFGQTEGLLGDEL----DLRELQKTGRVGRIA---ATLETIDR--------VGPCVATVKVIDIEDIRKKKREYIVERAVDCCDDIIVVEGRAD------VLNLLR--CGIKNVIAGTC--VPKTIIELCKKKIV--TVFTDGD--------RGGEL------ILKELLQV-CDVD---FVARAPPGK-EVEELCKKE----IMKCLDILYEK----TNLIFCKDA-KI-IKKPMLKPRIEKVVVNFGVGEC---GDRLTKGAQVIEELT-GQKPIRTRAKQTNPCFGIRKKLPIGLKVTLRGKKAEEFL-KNAFE--AFQKEGKK-LYDYCFDDYGNFCFGIHEHIDFPGQKYDPMIGIFGRICIARPPEVTAVRP-VVKACLEDYIFVCGPPGCGKCTFVAALAEFYRCQ-GK-IVKTMECPRDLQVCK---EITQYAPLEG------DMEKTCDIL--------LLVRPDYTIYDEVRKTRDFEIFADMRMAGV-GMVGVVHACKPIDAIQRLIGRVELGVIPQV---VDTVIFIKDGKIQKVYEIDFTVKVPYGMVE--EDLAR-------PV-IEVKDF--ETGRVEY-EGRCRRKPTGG-LYRPARK-KRKYEMGREPIETHVA--EEAFKIKKVRTRGGNLKVKVVRTGFANVLDPETGTCKKVKIITVRENKANIHYVRRNVITKGAIIETEIGLAKVTCRPGQDGTVNAILAGKIACKVREEAVKLI?PGVKLLEVAEFVENRIR-ELGGEPA------FP--CNICINEIAAHYTPKLNDNLEFKDDDVVKLDLGAHVDGYIADTAITLVKACEDALYTVIKEINPPMNIGEMGKIIQEVIECYGYKPICNLCGHVMHRYELHTGIC-IPNGDLVAIEPFAT--DGFGMVKDGNLGNILKERENGIVGQAEHTILITENGVEITTCQ-PKKCC-MECMKYCPICEVLCCG--CGICVKRCPFKAICIIGLPEELCEDKIVHCYGQNRFKLFGLVI-PRDG-VVGIIGQNGIGKCTVLRILAGELIPNKVQ-----YVDI---LPKVV--KGK-VGDLLKKVDEK---G-KFDEVVEKLELKNILDRELCQLCGGELQRVAIAAAYLRNGDIYFFDEPCCWLDIRQRFNAARLIREL--------NKVVVVEHDLIVLDYLCDYIHIMYGVP--SAYGIVCMPKCVRVGINEYLYG----ELREENIRFRFKLEVCGGT-IYKGEVIGILGPNGIGKTTFVKLLAG--VIKPDE------GY-------KPQYI-TPD---YDGTVEDLLLCGGELQRVAIAACLCRDADIYLLDEPCAFLDVEQRLRVCKVIRRIADEKEAGMFVVDH--------D
Methanococcoides_burtonii_DSM_6242                      GAE-VTITGCNPLCT-----QDAKYDCCCDEYYEAIDKVLD-----MKPDITIDDGADLIFKLHGGCEETTTGIHRLKAMEKDGALKMPVVAVNDAMTKFLFDNRYGTGQCCWDGIMRTTNLLVAGKTVVIGGYGW-CGKGVCLRACGLGAD-VIVTEPIRALEARMDGHRVM-SMAEADIFVTTTGNVDILCKKHFEVMKDGAILANCGHFNVEINLEELTAM-ACCVRTVRKN-IKE--------YNVA--GKRINVLADGRLVNLAA--GDGHPAEVMDMCFANQVHPVPHDLDMYVAELKLKCMGIEIDKLEPHQTEYMEGWDIGGLGDEIQRVREMIE-LPLKHHEIFQRLNVEPPKGVILYGPPGTGKTLIAKAVANEC-----RANFLYVAGPEIMGRFYGECEERLRKIFEEAAENAP------SIIFIDEIDCIAPKRENVTGEVERRVVAQLLTLMDGMEERG------QIVVIAATNRLDCIDPALRRPGRFDREIEIGVPDCDDRLEVLGADLLCLVQEACMRALRGPPGTGKTLIAQA---VANEANANFICIKGP--QMLCKFVDEIDCIATTRIADCETGRCCQQVVNQLLTELDG--LEPLKEVVVIAATNRPDMIDPALMRCGRFDRGVAHIKCCFNNTIITVTDLTGAETIAKCCGGMVVKAARDECCPYTAMQMATQLADILRDKGLEGVHIKVRAPGGN-KQRCPGPGAQAAIRAFARAGVRIGRIEDVTPVPHDGTRPK---GGRRRCAGRFGTRYGRRDRKLVADLEEKMHAAHKCACCAR-LTVKRVGTGIWKCKKCGYTFAGGTYIPVDAGAVKFVVNGADIMCPGIVKVDDGLNEGDLVGKAIKCIHYVGDYGYIRDAWKNPDE-TYVRDLRWERLQVWRKEGCVTRVERPTRIDRARCLGYKAKQGIVVARVKVRRGCMRKCRYIRGRRTQHTGKNKITV-GKCIQRICEERAARKYPNMEVLNCYWVGEDGKQKWYEVILVDPCHPVIKCDKNLNWICGKAHCGRVFRGKTCAGRKGRGMVIGIEHDPARCAPIAMVAFE---NGKKQFIVVPEGICVGEKLGVCAEVKPGNTLPLAEIPEGIPICNIECKPNDGGQYARCCGVYAMPCGVLKWFHPKCRATIGIVAGGGRVDRPFLKAGKKYHKMKARAAKYPRVCGIAMNVVDHPFGGGNRKH-PG--KPTTVCR-NAPPGRKVGHIAARRNIGIVAHIDHGKTTLCDNLLAGAGMICK--ELAGRQLFMDCDAEEQERGITIDCCNVCMVHEYEGKE----YLINLIDTPGHVDFGGDVTRAMRAVDGAVVVIDAVEGTMPQTETVLRQALKEHVKPVLFINKVDRLINELQVDDQEMQIRLGKLIDHVNKLINDMVIRFLPCPIDAQKGRVGAIWHGDHECGIGKQMCVADAKGDVAFMVTDICMDPHAG-EVCTGRLFCGCLCRGMEVYVCGA-SKTNRIQQVGVFMGPERLEVDAIPAGNIAAVTGLRDAFVGATECIKHACEPVVTVAVEAKHMKDLPKLVEVLRQVAKEDPTLKITLDEETGEHLMAGMGELHLEVIAH-RIERDKGVEITTTPPLVVYRETITGTA-GPVEGK------SPNRHNRFYVIVEPGIQYLNETMELIIEGFTEVMKAGPLCKEPCMGVKVKLMDAKLHEDAVHRGPAQVIPACRQAIQAAMLMADDTLFEPYQKVFIQVPQEQMGGATKEIQGRRGVIIDMTCEGDT-TVIECKAPVCELFG-FAGDIRCATEGRAMWCTEFAGFEPLPDPLADALCIIKNAEAVGKDCCTIRPACKLIGNVLKVMNDRGYIGDFEFVE-DGV-YTVELIGR---INKCG-------AIKPRYCVGVTEFER---WEK-QFLP--AKNFGVLILTTPKGVICQYEARENNVGGQLLCFVYGDATVALVGFPCVGKCTLLNKITPGLV-RGAACGRGRGREVIA-VVRNCNLG-------EYKIHNAVKDLIYDCLDFIRVYLKPQGGLADMDEPFRY-----SQVGLDHYLED----GDMTTAYDVPACDIIAKLAENLKEN-DQIKPPEWAAFVKTGVHKEHCPVDK-D-WWYIRCAAIMRTIYMQG-PVGVERLRCVYGGKKN--RG--ANPCRKAKGCGCVVREAFQQLETAGFVRKLKC---GRVIAPAGQCLLDNLCDANGLIMGRLACNVAGEE-VCIVNAERAVICGCKVTTFEEYD-VIRNMGT----REFGPYFPRRPDRILKRTVRGMLPY-KRARGGKANPGPPLGPALGPLGVNIKDVIEKINEKTKDYN--GMQVP-VKVIV--NDDKCVEIEVGTPPTCALILKELNIEK------GCGECGT-VVVGNLEIAQVAKIARMKKDDILCYCLKAAIKEVMGTCVPMGVTIENLDPRECQKAVDEGKVGMTHVIMIDDVKHCLTEGTEICVPVTIIETPAIRVAAIRA-YGKDTYG--EIAIAEGTMVEICDVFDNGKIVDVAAITTGHGTQGPVKRWGINLMK-NKHCRQGCLRQ-VGTLGP-WTPAHVCWRVPQAGQMGYHQRTDYNGFVNYGLVRGNYILIKGCVPGPCKRLIRLREPTRG-GIHPREAAQHHAFCQGPGLGACLRTVATCARALALCLDIPLVGVNHCIGHVEIGRWKT-----PAVDP-VVLYVCGGNCQVLAHRA-GKYRI-FGETLDIGIGNALDKFARGAGLTHP----GGPKVEEYAR------KA--TNYVKMPYVVKG-----MDFCFCGLCTENAFAMLVEVTERAGGVGANMRLREMLDLM-CEDRGACFYVPERRFMGDNGAMIAYTGLLMFNCGRIRLCGTCPVNLDGVCDQVKAIANRTGVCICGPVPLPTKKLVVPVRKCPCGDGTATWDHWEMRVHKRLIDI-AADERALRQLMRIQV---PKDICIEIIKFGLICPREVRKMCVTCIITADTYDDDGY-PIDMGLMDLRL-GVIDPGLKCKCCGCRAGEC---PGHFGHIELVAPVIHVGFNK----ILRKILRCVCCKCPY-------CRDRFENICD--DDR----PEWMILTVLPVPPVTVRPCITLECGQRCEDDLTHKLVDIIRINQRFQENRDAGAPQLIIEDLWELLQYHLTTYFDNEVCGV------PPARHR-SGRPLKTLTQRLKGKEGRFRGCLCGKRVNFCARTVVCPDPNLCINEVGVPLCIAQHMTIPVRVICKNIDLMREYVRRGREVHP-------GANYIERQMQDGDIVLFNRQPCLHKMCIMAHRVKVLPNKTFKLNPAVCPYNADFDGDEMNMHVLQTEECRAEACILMQV-QENILCPRFGGPII--GGIHDHICGLFLLTGKQIFCQILPDGYENKELEALPGRTLDETIEMRINCAVIMARCGARGCILNLTQMAACVGQQAVR--------GERIRRGRTLPHFDKGDL-GADAHGFVKACYKCGLNPTEYFFHAIGGREGLVDTAVRTCQCGYLQRRLVNALQDMGE--VAATMKIMPEGVDTDLDDLE-PVAFGLKALKLVVLVGDLE-GGTEPVEEAFAAVPGVACGPKGTNTRFLWYP-GVNIEVNGCE----ITYTCHITNMMKGVVDGFEYHMKVVYCHFPMQIKVNGKK--FVINNFLGEKKPRVCNIL-G-ETCVKA---SG-DE-VIVCGINKEDVGQTAANIGIDEAGKGPVIGPMCIGGVDCKKLCPKRRVHLAAQIDDLFPVVCAACILAKVRRDELIEKIKV---DMGGRARRPAIVVE---NGGYVEYLDAEEGICTGMVPYPEHNACPRNTMGAAMIKQGVCCCN-LKLRPDTRAHVLHY-PQKATRTQTCDAIH--FDERPA--------GQNFVVAYEGHNIEDALVFNKGCIQRGLGRCHFLRTFEGEERRYPGGD-KFEIP--DCEFR--GARCADAYANLDI-DGLVNPETVVRFL--EEQCDFG-IT--IEQRRECARCNEKGIVDTVLAKVKIRDERGDKFACRHGQKGVIGLIVPYHDMPFTENPHAIPCRMAHVLEMIGG-------KGKEVFCDGVTGKKIQADVFVGVILYQKLHHMVACKIHARCRGPVQVLTRQPTEGRAREGGLRFGEMERDVLIGHGAAMTLKERLLDECDKVVELVCAQ--CGYAFKLLLDEIKCLGVAPRLDCGLFINALNGFPGPYGTVEGEIAHEERGCG-GFGYDPIF-EY-------NG---NTFGELGAEEKKTAIARATVCVGTGKARINDIYEP-EFAKLKIIEPDIDVKVCGGGIMGQANAIRTAIARLRDAFMAYDRNLLVNDCRQTETKK--FGGPGARAKYQKCYRTKNANPGCNVYGERAWDARRCKLLYLGAACGTTVCHVCDML-PNGIVYAVEFCPRVAQPNQAQIAAVNGYLL--LCIKA-----RCIDTVANPCKVFKE-EVNKLVFYNPHMELN--RDDWCDDAYGLILENDLDPFGCPTPYLDAATRC-AVH--FLEVTATDTAPLCGAHFNCGMRKYAAVPL-NNEFHCEMGVRILLGKIARELAKHDKGMT--PLLCHATRHYVRTYLQVKKGAKLADKAFK-DLGLHGPAGVGKTCAAHALAMKRICVEE-------KIMCGVGVLEKLAECAGGDLRCAIKDLDAGIKRYVNLDPVIVPHTCGKHARQQFNKCDITIVERLVNNVMGKKQIALRIVDEAFDIVNCKTKKNPVQVLVEAVCNAGPREEVVRLKYGGICVPKAVDTAPQRRVDHALRNICIGCNQTA-FKCKRCAAECLACELIAACNRD-AK-CFCINRKDGKERVAKAARRG-SRTCGGGTTKNRRGAGNRGGRGRCGE---NKHHFT-RALQLG-------YIRGCERGFKVLGTGKVTKNMVVTACNFCEVARGKIETAGGGKTVAQLQ------EMCFEDFAELLPAKERRCIRR----GVRTHFRNMIIFPEMIGKNLEVYNGKEFVKIEIMPEMIGHRFGEYCPTRNRVCHGCAGVGATRCCKFVPLKVDNTGARTVEIICVKK-Y-RGVKNRMPKGGIGDMCVVCVKKGTPE---MRKQILYAVIVRQKKEFRRPDGIRVAFEDNAVVIVDDK-GI-PKGTDIKGPVAREAAER-FPKIGTTARLAAKVLGCGVHRVWL--NPEACCDIAVAITREDIRGLIACGCIKAEAVKGVCRGRARARDAKRR-YGHRKGHGCRKGTKGARN-PRKEQWMKKIRALRRKLKELRADGT-LDKCAFCKAYRKAKGGEYKNLAHMWVPQTRLGKLVFDGQVTCMDEAMDCGLPIRECKIVDLLL-PELGRRVKFRATVIVGNGDGFVGLGQAKDVQVGPAIRKAIDNAKINITRIKRGCGCWECGCGLPHTVPCEVNGKAGCVTVVLKPAPRGLGLAAGGTARKVLEKAGVKDVWTRTEG-----QTRTTLNFAKATYNALEYFAKQLCRAGYGGMDINRT-PMGTQITVYAEKPGMVIGKAGKVIRKLTRDVDRLYD-LDNPQIDAQEV---KRPELNAQMMACRLACCIERGWY-FRKAGHNTMRAVMNA-GALGCEIVICGKLTG-SRCRVEKMVNGYIKHAGKPVDDIVDDGFATAVKKLGTLGCKVRIIHP--DAVLPDLRQVMTPEARERLTRLRLCRKELVEQLECQLVMLAQNGRLQTKIDDEKLKVLLHCGCLDPHVTGLLPVMLGRATKAVCALRLCGKEYFTGPIYQTPPIICAVRQLRIRNIYYLDV--LGTYLRKLCHDIGLVLGCGGHMKQLRRTGTGPFREDTL--VCLPMEEGLCHLPKIIIRDCAVDAVCRGACLAVPGIAVFTLKGEAVPAVACPEGHVHFKNKL-MWTLGILVLYFALANIPLFGG--SLMLLGIGPIVTACIVLQLLVGA--DVIKLNMCD-PADQAFFQGAQKQICI-GGVLILFMDEIVCKG-----IGCGVGLFIVAGVTVAIFLMVVFVECTRIEIPPVKLIYACVLPMIFALF--WIETTGMGA-KPTAQKVFNCGMQIPGFRRNVGCIEKVMLRYIPKVTIIGGAFIGVLTLLACLL---GTIGGA-----GGTGLLLTVCIVYRLYEDIACEQMMEMHPLEGCGAVKFGD---FTLTCGKKCYIDIKKACCNPP--L--LLIRKATKGTGGR--FVG-DAT--KDDRIILLEDVTTCGGCVIEAIGAIREAGGKYAAHRLQQVRKDARWKDTGYCRRTL-GLDIKCDPLCGA------PQGRGIVLEKVGVEAKQPNCAIRKVRIQLIKNGRQATAFCPGDGAINFIDEHDEVTVERIGGRMG-GAMGDIPGVRFKVIA--VNNVCLREMVIGR----KEKPRRLVPIDEYL-----AAGVHIGTQQK--TQNMMK--FVYRVRT-DGLYVLDIQCTDERIRCIAHFLCMY--DPCRILVVCARQYGQYPATMFCKCVGAVCKVGRFIPGCLTNPVQEGFFE--------PDVVIVTDPAGDAQVIREAVNVGIPVVALCDTNNMTCNVDLVIPTNNKGRKALCLVYWLLAR-EI---ANERKQCIIIRDDLKLCKGKLAVQVAHAWKEGGQKKVVLRVEKLQDLFELKEKARREGLCTALITDAGLTEIAPGTVTVLGIGPARADYIDKVTGNLKLKYIIVTGGVMCGLGKGITTACVGRNLKNKGYKVTAIKIDPYINIDAGTMCPYQHGEVYVLKD--------G-----GEVDLDLGNYERFLDTELTRDHNLTTGKIYQTVIDKERKGEYLGKTVQIIPHITNEIKDRIDVCLIEVGGTVGDIECMPFLEAVRQMYREECPENIALLHVTLVP-IDCQGDQKTKPTQHCVKELRELGLTPHVIVCRCKKALMECTRCKIALFCDVPVEAVICAHDCADIYEVPLQLENEGLEDCYICIVECLKHDGILVPGGFGERGTEGKMLAIKYARENNIPYLGLCLGMQLAVIEFARNVVGLDGANCCEFDENTPYPVQEDV----VDMGATMRLGDYEATLKAGCLAECIY-GACLITERHRHRYEVNPN-YVDRIEEHG-----MIFC----G---KNKNRMEIAEV--PC--KDFYFACQFHPEFKCRPGRPCPPFRKFCECLDIAINLKNLDMCQ-PKNRVDEEIILPNGLG-KTMKIAVFAKGEVGLNAKDAGCDYILTEEDIKELGEDKCKARCLANECDFFIAEVQYMAQIGKAL-GAILGPRGKMPVRIRCKDKLTFHVCVGRRDMDVEKLAENIETVLGRLEHCLEKGKH--NLKCVYVTTTMGMAYPGKC-TKCYDT--PQHPWQAERMACEVELVKKYGLR---NKRELWKCLCVLRRF-RG--DARRLLIRFCIL---KCDCNIDDVLGLQTEAILERRLQTQVHRLGLARTARQARQFITHGHIAIDGKRVTVPGMMVTREQEMNVIRYPFITEKAMMLMD-ENKLQFVVDTRANKTQVENDVVKMYGFTVKCVCTKKALVTFNETD--AAHEIATRIGIIDLCGNCKGEIAL-PEVFCEIFRPDLIKKAVLCAQANRLQPYGTKLYAGMQTCA------HCWGC--GRGVAQVP-R--ICNGC-----R-VARIPQAVGGRRAHPPKTETDRTEKINKKEKRLAVRCAIAATIDADLVKARGHKFTA--EV--PFVADDAIEG-LVKIKEVICFLQAAGLYDDIIRAKEGK-HIRAGKGKRRGRKYKNRKCVLIVNLPGVDVATVTALNAELLAPGTHAGRLTVWTQCAARLKKGCKHYEVLVDPDGALEFK--KGG-N-VKIEDILAVECIFEDCGRGDHAAECDLTNAFQTDDVFEIAAYIIKHGEIQLTKEQRKHILEEKTRQVICTIARNAINPQ-TRAPHPPGRIEKAMEEAKVHIDPLKGVDEQVNIVMKAIRPIIPIRFEEVEIAVKIPCEYAGKCYGDIAKFG--TMLRDNWENDGCWVAVV-KIPAGMQNDFYGLVNHLTKGVHPIENGTVIDHINAGQA--------LNVLKILNIPT-SCCRV--VCVLINAPCVH-G-R-KDVVKIEGRELNVEEVDKIALIAPNATINIIRDFEVCDKDIVHIHCQIEGV--VRCINPNCICN-SN-EPVTCKFAV-SCNGQRTILRCCYCTNPRIPALICVLKDTARENDAPIWKDMAKRLEKPCRIYA--EVNLCKINRHAAEN-----DLVLVPGKVLGAGALGHA-VTVAALTFCTTAVDKITNAGGKC--MTIEQILE--ENPAGCGIRIPVRCFTCGKVIAGCWEEYKRRT--GEGE---DP-----ATVLDDLKFVRYCCRRMFLAHLKEGKYVLA------DDEPCVIKCIQKCKPGKHGCAKARIEAIGIFDGQKRCIICCVCAKTYVPIVERKCAQVQLMDMETYTTGKDITYIEA-MGKMKIKYIIHCKICADGIIDI-----VGAFGQTEGLLGCDL----DLRDLQKTGRIGRIA---ACLETIDR--------VGPCAAKIEITQVEDVRATKRKHIIERAVVECDAIVVVEGRAD------VLNLLR--YGIKNTICGTN--VPPEVAELTKKKTV--TAFTDGD--------RGGKL------IIKELLQV-ADID---YIARAPDGK-SVEDLVQRE----IVRCLDIACDK--GIENLIGVKKG-NI-AKCPMRNPKVEKVVVHMGVGEC---GQHLVDAEGILETIT-GQTVVRCYAKRTLPAFTIKKGEPIGCKVTLRGEAAEGFL-ETCLG--IV---EKR-LNECQFDIFGNVCFGVEEHTDYPGMRYDPNIGIFGRIAICTPPEITAVRP-VACVCLDDYILVCGPPGAGKCTFGAGVAIFLHEN-NY-VVKTMECPRDLQVPN---EITQYAPLEG------SMEKTADVL--------LLVRPDYTIYDEVRKTRDFEIFADMRLAGV-GMIGVVHANRAIDAVQRLIGRVELGVIPQV---VDTVIFIDKGEVAQVQTLEFTVKVPCGMLE--ADLAR-------PV-IVVCDF--ETCAPEF-EGRCRRKYTGA-KLKCARG-KRKFELGREPAATHVN--DT--KRKNVPTHGGNRKVRLLQENIANVTNPADGKTIVCAIETVVDNAANAHYVRRNIITKGCVIQTAAGNARVTCRPGQDGVVNAILAGEILCTVRCEAKEKVKIGTTLLEVADFVEQRTI-ELGGLPA------FP--CNICRNDEAAHATPLIGDETVFAE-DVVKLDLGVHIDGYIADCAITLVKACEAALYAAIDIIKNGINTAEIGAVIEDTITGHGFKPIANLTGHGVGQYLAHVPPC-IPNGDIFAIEPFAT--DGAGKVADGTLTEILKDVGGGLVCQTEHTVIVTDDGCKVTTCQ-PRRCC-HECEKYCPICEELCVG--CGICVNKCPFCAIMIIGLPEAL-DK-PTHRYGQNGFALYGLPT-PQVGKVTGILGPNGIGKCTCVQILCGALVPNKPQ-----YVDM---IPKAF--NGK-TRDLLEGTDER---G-VMDELVEKLDLGHIINRNIGELCGGELQRVAIAACAARDADFYFFDEICPYLDIYQRINCCKLIQDLAK-D----KAVLVVEHDLAILDMLCDVVQVAYGMP--SGYGVITHPKGVRIAINQYLKG----YLPEENVRVRFCLRCDCGC-LKEGEVIGIVGPNGIGKCTFVKILAG--EVEPDE------GY-------KPQYI-KVD---SFMQVRQFLLCGGELQRVAIAACLCKDADLYILDEPCAHLDVEQRCLATKAIKRFAENNGKTAMVVDH--------D
Methanococcus_maripaludis_S2                            GAK-IVITGCNPLCT-----QDAWRGETNEEYYENLNKVLD-----SNPDIIIDDGADLIFLIHGGCEETTTGIIRLKCMAEEGALKFPVVNVNDAYTKHLFDNRYGTGQCAMDGIIRTTNLLIAGKNVVVGGYGW-CGRGVACRAAGHGAN-VIITEPIRALEAKMDGFTVL-KMEEADIFVTTTGCKDILRMEHFLLMKDGAVLCNAGHFDNEINKNDLKEL-SKCVKEARFN-IEE--------YDLGN--KKIYLLGEGRLVNLAC--ADGHPCEVMDMCFANQVYEIPYEQDFKIALLKLHCMGADIDELCPEQRKYLCDWEVVGHHEIIKRLTNYVEKKCMPH--------------LLFCGCPGVGKTTAALALAKDLYGDTWRENFLELNCCD------ERGIDVIRTKVKDFARTKPIGDAPFKVIFLDECDALTCDAQ----NALRRTMEKYCDI---------------CRFILCCNYPCKIIPPIQ-----------------SRCAIFVENLKDICEKENLNLEK--PDEIKKMTQLA-------LNGKFVEAREQLYNLMIDW--------------------GEDILIQVFREVPNLDICEKEKVHLVEAIGECDF----RIVEGCNERGLVHIYACYNNTILHVTDLTGAETIAKVCGGMIVRNQRDECCPYAAMQAAFKIADLMRDKGIDQVHVKVRATGGQ-KCKNPGPGAQAAIRALCRAGIRIGRIEDATPIPHDGTTPK---RKNRGCAGRFGCRYGRKIRVRLRDVEIKQNKDYKCPVCAF-PKLKRAGTCIWVCEKCGAKIAGGAYTPVDMGAVKFIANGADIMAPGIVGADEDIKEGDIVGKAIKTIHFIGDYNYVKEAWKVPAN-SYVKELQWARMQDWRKEPCVLRIERPTRIDRARNLGYKAKQGIVVVRVCVRRGGLRKPRPKHCKKPATLGINKITM-AKCIQRIAEERAAKRYPNMEVLNCYWVGQDGKQKWYEIILVDPCHPCIKNDKCYCWLCTGNHKGRANRGLTCAGKKGRGLVIDILHDPGRCAPVAKVKFA---NDEERLVLIPEGIQVGEEIGICAEIKPGNVLPLGEIPEGIPVYNIETIPGDGGKLVRCGGCYALPCGFCKVLNPACRATVGVVAGGGRKEKPFVKAGKKYHCLCAKAVAWPKVRGVAMNAVDHPYGGGRHQH-IG--KPCCVCR-HTCPGRKVGHIACRRNMGICAHIDHGKTTLCDNLLAGAGMICK--ELAGDQLALDFDEEEAARGITIYAANVCMVHEYCGKE----YLINLIDTPGHVDFGGDVTRAMRAIDGAVVVCCAVEGVMPQTETVLRQALKEKVKPVLFINKVDRLINELKLTPEELQGRFMKIIAEVNKLILDMCIKHLPNPLTAQKYRIPNIWKGDAECTIGKCMVACDPNGPLAGVVTKIIVDKHAG-AICACRLFCGRIKQGDDLYLVGC-KQKARAQQVCIFMGAERVQVPCICAGNICALTGLREATAGETECLCHTCEPVITVAIEAKNTKDLPKLIEILRQIAREDNTVRVEINEETGEHLICGMGELHIEVITNTKIGRDGGIEVDVGEPIVVYRETIMGTC-PEIEGK------SPNKHNKLYMIAEPGIVQLDEARELIIEGFKEGVRNGPLAAEKVQGVKIRLVDATFHEDAIHRGPAQIIPAVRFGVRDAVAQAKPVLLEPMQCVYINTPQDYMGDGMKEINNRRGQILDMEQEGDM-SIIKCCVPVAEMFG-FAGAIRGATQGRCLWCVEFCGFERVPDPLANALNHVCNCECVGKNVAYLKPACKLIGRVLNVMQDQGYIGNFEYIE-DGV-YKVDLIGQ---INKCG-------AVKPRYAVKNHDFEK---FEK-RYLP--AKGFGLLIVCTPKGLMTHDEARNAGVGGRLICYIYGDATVAFVGFPCVGKCTLLNKLTPGII-SGACFGRGRGCEVLA-AVRNVDVG-------EHRIHNALKDKIFETLGFIKLYLKPQGGKADLEEPFRY-----ALVGLDHVLKD----GDMVTVYDVPANDLIAKLAEKLKEMG--VEEPEWTNFVKTGAHKERRPDDG-D-WWYVRCAAILRKVYING-PVGVERLRCVYGGRKN--RG--CAPEKFVKGCGNIIRTAFQALEAKELLTKAEK--GGRIIAPKGQCLVDNTA?????????????????????????????????????????????????????????????????????????????????????GKATAGPPLGPAIGPLGVNIMQVVQKINNMTKDYE--GMCVP-VKVIV-DTDKRTFEVEVGIPPACALIKKEIGIEK------GCQEPKH-QVAGNITMEQIVKIAKMKQDAMLAYNLKNACKEVVGTCVCVGICVEGMTPCEAQKAIDAGKAGTTHALLIENNPKCPNCCQEVFTPVTVLETPDVTVAGIRL-YEKTTKG--LKALTEGKTLAICDVFEAGEIIDTLAITKGKGFQGCVKRWGIKVQF-GKHQRKGVGRH-TGCIGP-WRPRRVMWTVPLPGQMGFHQRTEYNGFLNYGAVKNGYVVVKGTVQGPAKRLVVLRGCVRQ-GIHPREAADHHCFCLGPGLGPCLRVTATTARALCLCINKPIIGVNHCIGHVEIGKLTT-----DAVDP-LTLYVCGGNTQVLAYTG-KKYRV-IGETLDIAIGNCLDQFARHCNLPHP----GGVYVEKFAK------DG--NKFIKLPYTVKG-----MDLCLCGLLTETCFCMLTEITERAGGVAANNRLKEMLKVM-CEEQNVDFYVPEKQFCGDNGAMIAWLGILQYLNGRIKLCCTQHTELDGVCDQIKAIAEKTGVDMCGPIPLPTKALKVTTRKCTDGEGCCCFDRWTMRVHKRVIDI-EADERTMKHIMKVRI---PDTVQIEIITFGLLCPEQIRTMCVAKIVTADTYDDDGY-PIDGGLMDTRL-GVIDPGLVCKCCCGRVGTC---PGHFGHIELCKPVVHIGFAK----DIYKILKAVCPHCPC-------CREILEKIPA--EDR----PEFMVLTVLPVPPVTVRPCITLECGERCEDDLTHKLVDIIRINQRLEENINGGAPNLIIEDLWDLLQYHINTYFDNEAPGI------PPARHR-SGRPLRTLAQRLKGKEGRFRHNLAGKRVNFCARTVICPDPRLCINEVGIPKLIAKELTVPEKVTPYNIEKVRALLRNGCDNHP-------GVNYIERHLCDGDIVLYNRQPCLHRMCIMAHKVKVLPYRTFRHNLCVCPYNADFDGDEMNVHVPQCEEARAEAEKLMLV-EKHIVCPRFGGPII--GAIHDFICGAYVLTGKCLFCKTLPDGYENGTLECLPGRGVEECREAYINHAALMARTGARGCLLNITMMAACVGQQCVR--------GGRVFRGRTLPHFGKGCL-DAKCHGFVRCCYKKGLAPTEYFFHAMGGREGLVDQAVRTAQCGYMQRRLVNALQDMAT--VIAKVKVMPTCPEVEKECLE-PLAFGLYTVYVMVEMEEKE-GGMDPIEEAMNALENVVKCGAKELKRELMYP-GIEICTEDGK----VTYRCHIQNMITGVTDGFEYKLVIRYAHFPMKVCAKGNT--VMIDNFLGEKYTRTAKIM-D-GVTVKV---SG-ED-VVVCGANKEFVGQTAANIGLDEAGRGPVLGPMVIACVDCKQLCKKKREELYIIIDENYKIVCAACIIAKVTRDRVIEEYKE---TFGGRAVRPLIVVE---NGGIIEYLDAEEGIGAGVAPYPEHNCAPRITMAAAMCKQGIPMAN-IKWRMDTRGHLLHY-PQVPVRTKHQEILG--FDKRPA--------GQNFVVAYEGYNMEDAFIINKACLERGLGRCCFFRCYECFEKRYPGGD-KFEVP--EKGVR--GYRAEEAYRNLGD-DGLIDLECCVRFL--EEQEITL-QT--KCQRRDTCRHGEEGIVDLVLGKVRVRDLRGDKFACRHGQKGVIGLIVPQEDLPYTENPHAIPCRMGQVLEMIGG-------KAKEAMYDGKCGRKLECDIFVGVAYYQKLHHLVAGKIHARCRGPIQVLTRQPTEGRAREGGLRFGEMERDVLVAHGAAMLLKERLLDECDPHEDYVCAK--CGYAFKLLLDELKCMGIDPKLDCGFFIEKLNDFPGTYGIVKGTICTEIKDGGFGFAYDCIF-IP-------EGKT-KTFAEMTTEEKRTAIARATAKEGCGKIRINELMEP-KYIKMKLMEPDVDIDVKGGGIVCQMDATRTALGKLKEKFLCYDRTLLVCDARRTEPHKPCKCCKGPRAKRQKCYRTKCLVPGKRVYGERIWNPNKCKLLYLGACAGTTPCHVADIA-ENCLVYALEFAPRVAQPNQAEILVKNGYAM--ICIKA-----RCVDVTKNPREIFAE-QKKILVFYNPVMETN--RDDINPCAVKMIKENDLDPFGCPVPYLDCGIRACLTKGGLLCMTATDTAVLCGAYRKTCIRKYNAVPL-KGD--KELAVRLMIGYAVKMACKYDIGLK--PIFCHVTDHYARTFMVTERGAGKADCAIE-NLGLAGPPGCGKTTLAYAIALRRIALKE-------GFEIDEKIIKMIACHCGGDLRAAINDLDPCLKCYICVAPVLVPHTAGRNCKKCFDKCKMNIVERLANKLMGKKHETLAIVEEALTIIENRTKENPVQVLVDALENCGPREETTRICYGGIAFLQCVDVCPCRRLDTAFRNIALGACECA-HKNKKTVAQCLADELIFACKADMQK-SFAVKKKEEKERVAQCARRG-SRTCGYGEAKKHRGAGHRGGRGNAGH---QKHKWL-SVCKFNPD-----YFG--KYGFKVLGKGRICTAMVVKAVEFCEGAKEKIEAAGGGFCLEELQ------EMPIKKFMEIVPCRQRRTMAR----GIRTHCRDFVITPEMIGLTFGIYNGKEFKEIKLVEETVGRFLGEMAPTRGVVQHGCPGMGATRGCMFVPIKADNTGAKELEVIAVKN-Y-VGTVRRLPAGGVGHMVFVCVKKGTPE---MRKQVLPAIIIRQKKEYRRADGTRVKFEDNAAVIVTPE-GT-PKGCEIKGPVCKEAAER-WPGVCRLARIAAAVLDCGIDRVWI--DPENLEKVKMAITKDDIRLLINDGIIVKKQEKGICCARKKEVQEQKR-KGKRKGPGCRKGAKGART-PKKEKWMNTIRPLRKMLKELRENEK-IERCAYRKLYRMAKGGAFRCRNHMWEPKTQIGRMVKEGTICDICYIMDKGLPLLEPEIVDALL-PDLGRRARYRATVVVGNKNGYVGVGMGKCKEVGPAIRKAIAHAKLCLIKVRVGCGCWECGCGCPHCIPFTAKGACGCVKVELLPAPRGVGLVAGNVAKAVLGLAGVKDAWTKTFG-----DTRTTYNFAEATFDALEYFKTKLVRAGYCHIDFKKT-PIGTRITVFAEKPGFVIGRKGKMVKELTETLATEYC-VKNPQIEVKQV---ENPDLDPAVVGHKIACCLERGMH-FRKTAHCAIRRVMGC-GAKGVAIIVCGKLCG-ERCRTEKFMDGYMKHCGEPAEALVNKCHQLAKLKLGIVGVTVKIMRP--DVCLPDLRQILCEEARCRLARIKLAKPQFAEQVEMQLIQLAQAGKLPVPLTDEYFKGLLHGGTLDPKVTGALPVALGNTTKCVPIWHIPPKEYFTGRIHQRPPLKAAVRCLRIRKIYEIEI--LGTYLRKLVDDMGEALGTCAHMQELRRTICGPFYENEA--VYLPLEYGLQHLKKIIIKDCAVDAVCHGATLYCCGVLIETLKGEAVPEVKRPLREICFKEKL-QWTALVLVLYFILGTIDIYTG--TLITLGIGPIVTAGIIMQLLVGC--ELICLDLCK-PMNRALFQGLQKQLAL-GAILIIYLDEIVCRG-----IGCGIGLFIAAGVTILVFLVVVYVECIRVEIPPIKFIYVCNLPVIFGLF--WVETCGLDA-KCMAKKLGNLDMAIKGFRKCQKCIEQRLKRYITPITVMGCAFVGFLAAAADFT---GALG-------GGTGVLLTVCIVYRLYEQLVQEQLCELHPLKDVNCVKFGD---FTLACGKQCYVDIKKATTNPD--L--LIIRKKAKGTKNK--IEG-ELN--PGDNVIVMEDVTTTGGCVCKAVDEIRAVCGEFAGRKLLLKRKACRWHHYKYVNKAL-SLKLKADPLEGA------PMGRGIVIEKVGLEAKQPNCAIRKVRVQLIKNGRQVTAFAPGNHAINFIDEHDEVVIEGIGGPCG-QAKGDIPGVRYKVVL--VGKNCIRELVRGR----QEKVKRLTTLDTYL-----ACGIHIGTQQK--TEDMRR--FIYRVRA-DGLYVLDVRKTDERLRLAAKFLCNY--EPEDIMAVTRRVYCVGPLKEFGKVTGINTVAGRFVPGTLTNPCARKFAE--------PEVLFLCDPRVDKQALKEAIEIGIPVIGMCDTEHLTAHIDFIIPTNNKGRKCVCLMYYLIAR-EY---MKNREQAIVIRNDLKMGKGKMAAQACHAWMNEGQKKVVLKVNCEKELLEIFKNVNIEGLPCCLIRDAGRTQIEPGCLTAVGIGPEKEEKICKVKKDLKLKYIFVTGGVVCCLGKGITCCCLGRLLKARGLNVNMIKIDPYLQIDAGTMCPFEHGEVFVTDD--------G-----GETDLDLGNYERFVDIGLKADNNITTGKIYWCVLCKERKGDYLGKTVQVIPHITNEIKDRIDITIIEIGGTVGDIECLPFLEAIRQFKKDVGKENVLYIHVCLLPYIRCAGELKTKPTQHCVKELKGIGIQPDILVCRCEIPICEKIKDKLALFCDVEKEAVIECKDARTIYEVPLNLEKEGLKDCYMCIMEALGHHGILVPGGFGDRGIDGKVNAVRYAREKNIPFLGICLGMQCAVIEFARHVCGL-NANCTEFDEETEHPVQREV----TEKGGTMRLGAYPAVLTENCLACELY-GCINACERHRHRYEVNPE-YHEILKKNG-----LIIC----GMC-PDGKLAEFIEL--EN--HKYFIATQAHPEFKCRPNKPHPLFRNFTQCVDLIVNLKELDLCR-PENRLKEQIVLPCGRG-KDVAIAVIAKGDLAAQAEDMGLT-VIRQEELEELGKNKKTAKKIANAHGFFIAQADMMPLVGKCL-GPVLGPRGKMPVAINTRDKALFQVYIGTECMCDDELAANAEAILNVVCKKYEKGLY--HVKNAFTKLTMGMGDPRRL-GKKYDT--PNHPWIGERIQKEKEICQKYGLV---NKKELWKMETQLRNY-RR--QARKLLKRYAIL--IEEEPTLDHVLCLNIECILERRLQTIVFRKGLAKTPKQARQFIVHGHIAVNGKRVTAPAYLICVAENDAIIKTPIVCEKTMKLIEEENRLVFYVERKATKADVRAAIKELFDAEVADINTKKAYITLKDEY--NAGEVAACLGVYNLDGCEKGDIEL-PAVFEAEYRPDLIKRAVICCLTAKLQPKGCDAFAGYRTCA------KCIGK--GHGKARVR-R--TAQGA-------GAFVPQAVGGRRAHPPKVEKILFERINRKEKLKALACAIAACANPEIVCARGHKIEGVPCL--PLVVNAEFEC-LVKTKEVLEVFKTLKLDADLERAKDGV-KIRAGRGKLRGRKYIKPKCVLVVNLAGVDVITANDLCAIHIAPGTMAGRLTLWTENAARLQCHGEKFEILVDPYLAAKFK--EGQ-P-IGICEILAAETVYKDCGKGEKVPEDVLLKIFETLNPLEIAEQILKKGTVQLTANQRKEIQELKRKQIVCIICKNTINPQ-TDTPHPPKRIENAMEEARLCVDIYKCAEEQIPKIIKELRKLLPIKFEKRDVAVKILGEFAANAYHTLHEYG--ATKQEEWLGDGCLVLVI-EIPCGIENEFYMHLNKLTKGVKPIENGTVIDHICGCKA--------LKVYKILNI---EEKLP--ITLALNVPCKKGV-T-KDILKIEGLELCKDDVNKIALICPDATINIIKEGKVIKKFKVDIPKRIDGI--IKCTNPNCITN--K-ENIECRFCIE-QKN-TLKIRCEYCTNPKTPELIQKLKEECFKNCAPIWKDVAKKLAKPARKKV--EVNVCKICRYACEG-----DVLLIPGKVLGAGCLKVN-VTVAAFCFCETAKCAIEAVGGKC--LTIEELIA--ENPKGCKVTIPIRCFCCGNVICEVYEEYRTRL--KNGE---NP-----EEILNDLEIKKYCCRRMFACHLKVGQYVVI------DGIACRVMDTAHCKPGKHGGAKVRLTAMGIFEPVKKEHVGPACCRIDVPLIDKRKGQVQIMDLETYETGVEVEYFEA-MDRYKIKYIIYTELIADGYVDV-----IGAFGQTEGLLCNEL----DLRDLQKCGRIGRIA---ATLETIDR--------VGPCFATVKITEVEDIRVCKRQYITNRAIIHCDCIIVVEGRAD------VLNLLR--CGIKNTVAGTC--VPKCIMELTKKKTT--TAFTDGD--------RGGEL------ILKELLQT-CDID---YVARAPYGK-EVEGTCKKE----LMKCLDLLYDK---TPIIVGKEI--NV-TKKPMKKPRIQKVTVNFGVGEA---GDRLTIGAKVIEELT-GQCPVRTLAKQTNPAFGIRKKLPIGLKVTLRGKKAEEFL-KNAFT--AFKACGKT-LFACCFDQVGNFCFGVPEHIDFPGQKYDPCVGIYGRICIARPPEVTAVRP-ITKVCLEDYIFVCGAPGCGKCTFVCALAERYKNM-DK-IVKTMECPRDLQVDE---EITQYAPLEG------SMEKTCDIL--------LLVRPDYTIYDEVRKTKDFEIFADMRMAGV-GMVGVVHACKAIDCIQRLIGRVELGIIPQI---VDTVVFIENGKIGKVYEVEFNVKVPHGMKE--ADLAR-------PV-IEVVDF--LTKTPEY-EGACRRLCTGA-KVWRAAK-KHKREMGRPAAETQVC--DKI-KRKIVRCRGANLKVKLEKTNYANVFDQANKVCKKVVVTNVIDNKANKHYIRRNVMTKGAIIETEMGKAKVTCRPGQDGVVNAILAGKIACQVKEEAVKLVKPGAKLYDVAEFVENRTR-ELGAGVG------FP--CNICLNDIAAHYCPCYGDNCIFCEEDVVKLDLGCHVDGFIADTAVTLKKACEDALNTVIKEIMPEMNIGEMGKIIQEVIECYGYRPVCNLCGHVMHQYCLHCGVC-IPNGDLVAIEPFAT--DGFGQVVDGKDVYILVEREHGMVCQCEHTVLVTENGVEITTCQ-PRRCC-MECMKYCPICEELCCG--CGICTKRCPFGAIRIIGLPEELTDDRIVHCYGQNRFRLYGLIT-PRDG-VTGLLGPNGVGKCTIIKALCGEMVLNKPQ-----YVDV---LPKVV--KGK-VGELLKKVDEK---G-EFEKIINALEICNILDRTFDQLCGGELQRVAIAAACLREGDIYYFDEPTCWLDVKQRFCAAKVIREVAE-----GKKVVAVEHDLIVLDYLCDYIHIMYGIP--SAYGVVTHPRGTRVGINTYLDG----FLKEENIRFRFCLNVNGGQ-IYQGEVVGILGPNGIGKTTFVKALAG--VICPDC------GY-------KPQYI-SCD---FEGTVEDLLLCGGELQRVCIAACLCQDADLYLIDEPCAFLDVEQRLTTCRVIRRMADEKEAAMFVVDH--------D
Methanococcus_voltae_A3                                 GAE-IIITGCNPLCT-----QDAWRGETNEEYYENLNKVLD-----AKPDVVIDDGADLIFLLHGGCEETTTGVIRLKAMAQEGALKFPVINVNDADTKHLFDNRYGTGQCALDGVLRTTNLLMAGKTVVVAGYGW-CGRGVAMRADGHGAN-VIVTEPIRALEARMDGYQVM-PMCEADVFITTTGCKDILRTEHFLLMKDGAVLCNAGHFDNEINKNNLNEL-ACEVNVVRNN-IEE--------YKVNN--KRIYLLGEGRLVNLAC--ADGHPCEVMDMCFANQVYEIPYEQDAKIALLKLKCMGCEIDELTPEQKKYLNDWEIVGQKEIIERLKNYVEKQCMPH--------------LLFCGCPGIGKTTAALCLAKDLYGDDWRENFLELNCCD------ERGIDVIRTKVKDFARTKPIGDAPFKVIFLDECDALTCDAQ----NALRRTMEKYCDI---------------CRFILCCNYPCKIIPPIQ-----------------SRCAIFNITIEKCGCDAII------PDEIKKMIDLA-------INARFMEAREQLYKLMIDW----------REVPYLD-------------------IEENEKVCLIEAIAECDF----RIVEGGNDRGVVHIYACYNNTILHVTDVTGCETIAKVCGGMIVRNQRDECCPYAAMQAAFKIADLIRDKGIDHVHVKVRGAGGQ-KCKNPGPGAQAAIRALCRAGIRIGRIEDATPIPHDGTTPK---RKNRGCCGRFGPRYGRKLRVRLRNVEMKQKKAYKCPVCGF-PKLKRAGTCIWVCCKCNAKLAGGAYTPVDCGAVKFLANGADVMAPGIVNANPEIEEGCLVGKAICTLHYIGDYKHIQEAWKKPAE-SYVKDLQWVRMQDWRKEPTVVRLEKPTRIDRARNLGYKAKQGVIVVRVAVRRGGLRKPRPKHCKKPATMAVKKITM-AKCIQRIAEERAAKRYPNMEVLNCYWVGEDGKRKWYEVILVDINCPTIKNDKKYCFLADGANKCRVYRGLTCAGKKGRGLLIDVLHDPGRCAPVGKVRFE---NGEERLVLIPEGKKVGDEIGICAEIKPGNVLPLAEIPEGIPVYNIETIPGDGGKLVRAGGCYALPCGYPKVLNPCCRATIGVVAGGGRKEKPLLKAGKKFHALCAKAVAWPRVRGVAMNAVDHPYGGGRHQH-TG--KPTCVCR-HTCPGRKVGHIACRRNIGICAHIDHGKTTLCDNLLAGAGMICK--ELAGDQLALDFDEEEAARGITIYAANVCMVHQCETGE----HLINLIDTPGHVDFGGDVTRAMRAIDGAIVVCCAVEGVMPQTETVLRQALKEKVKPVLFINKVDRLINELKLTPEELQARFMRIIAEVNVLILDMVIKHLPNPVQAQKYRIPNIWKGDIECEVGKCMMVCDPNGPLAGVITKIIVDKHAG-AICACRLFCGRMKQGDELFLVGA-EQKARAQQVCVFMGAERVQVPCICAGNICAITGLKEATAGETEGLCHVCEPVITVAIEAKNTKDLPKLIEVLRQIAREDNTVRVEINEETGEHLICGMGELHIEVITNTKIGRDTGIEVDVGEPIVVYRETINGTC-PEIEGK------SPNKHNKLYFIVEPGIVQLDEARELIIEGFKEAVRNGPLAAEKVQGVKVKLMDATFHEDAIHRGPAQIIPAVRFGVRDAITQAKPVLLEPMQKVYINTPQDYMGDGMKEINNRRGQIVDMEQEGDM-SIIKGCVPVAEMFG-FAGAIRGATQGRCLWCVEFCGFEKVPDPLANALNHICNCENVGKNTAYLKPACKLIGRVLKVMQDQGYIGNFEYIE-DGV-YKVALIGQ---INKCG-------AVKPRFAVKNQEFEK---FEK-RYLP--AKGFGLLIVCTPKGLMTHDEAKDAGIGGRLICYIYGDATVAFVGFPCVGKCTLLNKLTPGII-SGACFGRGRGCEVLA-AVRNVDLG-------EYKIHNALKDKIFDTLGFIKLYLKPQGKKADMTDPFRY-----AQVGLDHVLGD----GDMVTVYEVCPNELIEKLAEELKEIG--IQEPEWTLYVKTGAHKERRPDDA-D-WWFVRCACILRKVNMNG-PVGVERLRCAYGGRKN--RG--CAPERFVKGCGNIIRKALQALECKDLILKAEN--GGRIICPKGQCLLDNVANAENAVVGRLACYVAGEE-VVIINAEKAIMTGNKEFIFQKYV-QLRNRKCICNPKKMGPKFPRRPEDILRRIIRGMLPY-KKPRGGKATAGPPLGPAIGPLGVNIMQVVNEINQKTACYE--GMCVP-VCVIV-DTEKRCFKVEVGIPPACALIMKELGIEK------ACQEPKH-QVAGNLTMEQVVKVANMKYEAMLCFNIKNACKEVIGTCVCLGVNVEGKTPREAQKAIDAGKAGVTHALYVENNPKCPNAEQEVACPVTVLETPNITIAGIRV-YKKDTNG--LKVLTEGQKLCINDVFEAGEIIDTVAVTKGKGFQGCVKRWGIKIQF-GKHQRKGVGRH-TGCIGP-WRPRRVMWCVPLPGQMGFHQRTEYNGFLNYGVLKNGYVLVKGTVQGPAKRLVMIRGAIRQ-GINPREAADHHCFCQGPGLGPCLRVCATAARALALCLNKPIIGVNHCVGHVEIGKLTT-----PAKDP-LTLYVCGGNTQILAYVG-DKYRV-IGETHDIAIGNCLDQFARCCGLPHP----GGVYIEQMAKKC----EAKDENYLKLPYTIKG-----MDLCLCGLLTETAFAMLTEITERAGGVAANDRLKEMLQKM-CEEQNVEFYVPEKQFCGDNGAMIGWLGILQYKNGRIKLCCTKHTELDGVCDQIKAIAEKTGVDLAGPIPLPTKTLKVTTRKCTDGEGCCCFDRWTMKIHKRVIDL-EADERTMKHIMKVRI---PETVQIEIITFGLLCPEQTRIMCVAKIVTADTYDDDGY-PIDGGLMDTRL-GVIDPGLVCKCCGGRVGTC---PGHFGHIELCKPVVHIGFAK----DIYKILKATCPHCPE-------CREILEKIPA--NDR----PEYMILTVLPVPPVTVRPCITLECGERCEDDLTHKLVDIIRINQRLEENINGGAPNLIIEDLWDLLQYHINTYFDNEAPGI------PPARHR-SGRPLRTLAQRLKGKEGRFRHNLAGKRVNFCARTVICPDPRLCINEVGIPELIAKELTVPEKVTAHNIDHIKELLKNGCEIHP-------GVNYVERHLIDGDVVLYNRQPCLHRMCIMAHKVKVLPYRTFRHNLCVCPYNADFDGDEMNVHVPQCEEARAEAETLMLV-EKHIVCPRFGGPII--GAIHDFICGAYVLTGRCLFGTALPDGYETGTLDPLPGRGIEECREAYINHAALMARTGARGCLLNITMMAACVGQQCVR--------GGRVFRGRTLPHFGKGCL-DAKCHGFVRCCYKKGLCPCEYFFHAMGGREGLVDQAVRTAQCGYMQRRLVNALQD??????????????????????????????????????????????????????????????VKCGGKQLEKTLNYT-GIEFCLEDDK----LTYKAHALNMIKGVTEGFDYKLAIKYAHFPMKVCVKGNI--VIIDNFLGEKHPRNAKVM-P-NVTVKV---SG-EQ-VIVCGINKEFVGQTAANIGLDEAGRGPVIGPMVIAGVDCKKLCKKKRETLYKEIDDNYKIVCAACIIAKVNRDNIIDCYNEKYEALGGRAVRPLVVVE---NGGLVEYLDAEEGIGAGVAPYPEHNCAPRITMAAAMCKQGVPMAN-IKWRMDTRGHLLHY-PQVPVRTKHQEILG--FDKRPA--------GQNFVVAYEGYNMEDAFIINKACIERGLGRCCFFRCYECFEKRYPGGD-RFEVP--EKGVR--GYRAEGAYRNLGG-DGLIELECEVRFL--EENEICL-QQ--KCQRRDTCRHGEEGTVDLVLCKVRVRDCRGDKFACRHGQKGVIGLVVPQEDLPFTENPHAVPCRMGQVLEMIGG-------KGKETVYEGKCGKKLECEVFVGVAYYQKLHHLVAGKIHARCRGPIQVLTRQPTEGRAREGGLRFGEMERDVLVAHGAALLLKERLLDECDPHEDYVCAK--CGYAFKLLLDELKCMGIDPKLDCGLFIECLREFPGTYGTVEGTICYKMKCNGYGFAYDCIF-VP-------KGCE-KTFAEMLPAEKRTAVARATAKEGNGRIRINELIDC-KYLKMKLMEPNIDIDVKGGGAVGQAEAVRTALGKLKDKYLAYDRTMLVCDARRTEPHKPCKCCKGPRAKRQKCYRTKCLVHNKRVYGERVWNPNKCKLLYLGACAGTTPCHVADVA-ENCPVYAVEFAPRVAQPNQAEILIKNGFGM--ICIKA-----RCVDVTENPKVIFEA-QKEIMVFYNPVMEIN--RDDINPNAIRAIHENDLDPFGCPAPYMDCGIRCTLTKGGIVCMTATDTAVLCGAYHKCCIRRYNCVPI-RGD--KEYAVRILIACAILNAAKYDIGLR--PLFCHCTDHYVRTFMITERGAGKAEKAME-NLGLAGPPGCGKTTLAYALALRKIALQE-------GYEVDPKAIKMIACHACGDLRAAINDLDPCLRCYICLEPVLVPHTAGRFCKKMFDKCKMNIVERVLNKLMGKKYEALAVMEEALEIIEKRTKENPVQVLVDALENAGPREETTRICYGGIAFLQCVDVCPVRRLDTAIRNICLGALNCA-RKCKKCIANCLAEEIICACKADMQK-SFAVKKKEEKERVAQCARRG-SRTCGYGEAKKHRGAGHRGGRGNAGV---QKHKWL-SICKFNPD-----YFG--RCGFKILGKGRICLAMAVCAVEFCENAVAKLEAAGGGYTLEQLQ------EMPVKKFMEIIPCRQRRTMKR----GIRTHCRDFVITPEMIGLCFGIYNGKAFKEVKLVEEAVGRFLGEFAPTRAVVQHGCPGMGATRGCMFVPIKADNTGAKELEVICVKN-Y-SGVVRRLPAAGVGQMVFVCVKKGTPE---MRKQVLPAIIIRQKKEYKRADGCRVKFEDNAAVIVTPE-GT-PKGCEIKGPVCKEAAER-WPGVCRLARIAANILDCGIDRVWV--DPENLEKVKLAITKDDIRALVKDGIIVKKQEKGICCARKKKIQEQKR-KGKRKGQGCRKGAKGART-PKKEKWINTIRPLRRMLKEMREEDK-IERTQYRKLYRMAKGGAFRCRNHMWEPKTQVGRLVKEGQITCIDEIIDKGTPILEPEIVDVLL-PELGRRARYRATAVVGNKNGYVGVGMGKAKEVGPAIRKAIAHAKLCLIRVRVGCGCWECGCGGPHCIPFTADGNCGCVKVQIIPAPRGVGLVAGNVAKCVLGLAGVKDVWTKTFG-----DTRTTYNFALAVFDCLEYFCKKLVKAGYCHIDVKKT-PIGTRITVFAEKPGFVIGRKGKMVKELTETLRTVYK-IENPQIEVKQI---ENADLDPAVVGHKIAACLEKGMH-FRKTAHCAVRRVMNA-GAKGVCIIVCGKLCG-ERCRTEKFMDGYMKHCGEPCEELVMKCHQLAKLKLGVVGVTVKIMLP--DVCLPDMRQILCEEARCRLARIKMAKPQFAEQVEYQLIQLAQCGRLPIPLDDDRFRVILHGGTLDPKVTGALPIALGNCTKCVPYWHIPPKEYFIGKMYQRPPLKACVRKLRVRKIYELKL--IGTYLRKLVDDFGEALGVCAHMQELRRVKCGPFFEEEA--IYLPVEYGLQHLQKVIIKDCAVNAICHGANLYANGVLVETLKGEAVPEVKRPDRDICFKGKL-YWTGIVLLLYFILGTIDVYTG--TIITLGIGPIVTAGIIMQLLIGC--ELVKLDMCK-PDNRALFQGLQKQLAI-GAILLIYLDEIVCRG-----IGCGIGLFIAAGVTICVFLVVVYAECIRVEIPPIKFIYVCNLPVIFGLF--WVETCGLDA-KCMAKKLGGLNMAIKGFRKCNKCIENRLKRYIKPITVMGCAFVGLLAALADFT---GALG-------GGTGVLLTVCIVYRFYEQLVQEQLCDLHPLKEVNCVKFGD---FTLACGKKCYVDIKKATTNPD--L--LIVRKKAKGTKNK--IEG-ELN--PNDNIIVMEDVTTTGGCVLKAVEELKECGGEFAGRKLFLKRKECKWHQYKFVNREL-SLKLKADPLEGA------PMGRGIVVEKVGLEAKQPNCAIRKVKVQLIKNGKVITAFAPGNHAINFIDEHDEVVIEGIGGPCG-QAKGDIPGVRYKVVM--VGKNCIRELVKGK----QEKVKRLTCLDTYL-----ACGIHIGTQQK--TEDMRR--FIYRVRA-DGLYVLDVRKTDERLRLAAKFLCNY--EPEQILAVCRRVYTVGPLEKFGKTTGIKTLAGRFVPGTLTNPACRKFME--------PEVLFLCDPRVDKQALKEAIEIGIPIVGMCDTEHLTCHIDFIIPTNNKGRKCVCLMYYLIAR-EY---MKNREQVIIIRNDLKMGKGKIAAQACHAWMNEGQKKVVLKVNCECELLEVFKNANIEGLPVGLIRDAGRTQIACGTLTAVGIGPEKEEKICKITKDLKLKYIFVTGGVVCCLGKGITCCCIGRLLKARGFKVNMIKIDPYLQIDAGTMCPYEHGEVYVTED--------G-----GETDLDLGNYERFVDLDLLADNNITTGKVYWCVLCKERRGDYLGKTVQVIPHITNEIKERIDITIIEIGGTVGDIECLPFLEAIRQFKKDIGKENVLYIHVCLLPFIRAAGELKTKPTQHCVKELRGIGLQPDILVCRTEIPMGEKMREKLALFCDVEKEAVVEARDAKTIYEVPLNLEKEGLKDAYMCITEALIHDGILIPGGFGDRGVDGKVNAVKFARENNIPFLGICLGMQCAVIEYARNVCGLECANCTEFDEKTPYPVQREI----TEMGGTMRLGAYEAHLTDGTLAKELY-GTDTAWERHRHRYEVNPE-FHEVLTNEG-----LIIC----GTC-PDGKLAEFIEL--KD--HPYFIATQAHPEFKCRFCACHPLFRNFTQCVDLIINLKELDLCR-PENRMKQQIVLPCGLG-KEINIAVIAKGDLAAQAECMGLT-VIRQEELEELGKNKKQAKKLANANQFFIAQADMMPIVGKCL-GAVLGPRGKMPICINTRDKAFFQVYVGKECMCDEELAANIETVLNTVARKYEKGLY--HVKCAFTKLTMGMGDPRRL-SKKYDT--PNHPWIGERINKERDLCQKYGLI---NKKELWKMETQLRNY-RR--QARKLLKRYGIL--NEQEPTLDHVLCLNIENILDRRLQTIVYEKGLARTPKQARQFIVHGHIAVNGRKVCCPCYLVELEECDAIIKTPIICEKTMKLIEEENKIVFYVERKATKEDVKKAMKELFEVEAKCINTKKAYITLKEEY--DACEVAANLGIFNLDGCEKGEVAI-PCVFCAEYRPDLIKRAVICCLTAKLQPKGCNLLAGHRTCA------KCIGK--GHGRARVR-R--TAQGG-------GAFVPQAVGGRRAHGPKVEKILLERINRKERLKALQCAIAACANVEIVKARGHIIPDVPAL--PLIVCEEFEC-IVKTKDALDVFKALKLDADLTRAKEGI-SIKAGKGKLRGRKYKKPRCVLVVNIAGVDVITADDLGTMHIAPGTAAGRLTLWTEGAARLQCHGEKFEIYVDPYLAAKYK--ENQ-SCADICDILACEHIYKDIAKGEKAPDELLMKVFETLDGKKIAEKILMKGQVHLTAEQRKEMQEQKKKQVICFIARNTINPQ-TDTPHPPKRIENAMNEARVCIDLYKCAEEQVNDVIKKLRLILPMKFEKREVAVKLGGEYAGTLYHCLAEYG--TIKKEEWMGDGCLVFVI-EIPCGIENEFYMFLNKITKGVKPIENGTVIDHIECCKA--------LNVYQILNM---PKDTT--LTLAMNVNCKNGA---KDILKIEGKELCECEVCKIALICPNATINIIKDCKVLKKFKVQVPDEIEGI--LICTNPNCITN--K-EKVNGKFTIE-DKE-KLKIRCNYCTNPEVHGLVQFLKEAAFKNEAPIWKDVAKRMAKPCRRRA--EVNICKINRYACEN-----DTIVVAGKVLGAGCLKQN-VTVAAFTFCNCAKLAIEAAGGKC--ITIPELVE--QNPKGCKVVIPVRCFCCGTVVCEVYGEYHERL--TNGE---KC-----DEILDDLDITKYCCRRMFACHLKEGQYVVI------DGIACRVVGTAHCKPGKHGGAKVRLTAMGIFEATKKEHVGPACCRIDVPLIDKRKGQIQLMDLETYETGVEVEYFEA-MGRYKIKYIIYAELMADGYVDV-----IGAFGQTEGLLCNEL----DLRDLQKCGRIGRIA---ATLETIDR--------VGPCLATVNITNVEDIRICKRHYITERAVIHCDAIIVVEGRAD------VLNLLR--CGIKNAVAGTC--VPKCIIELTKRKTT--TVFTDGD--------RGGEL------ILKELLQT-CDVD---YVARAPYGK-EVEETCKKE----ILKCLDKLYDK---TKLIIGKNV--NV-SKRPMKKPRIQKVTVNFGVGEA---GDRLTIGAKVIEDLT-GQAPVRTLAKQTNPAFGIRKKLPIGLKVTLRGIKAEEFL-KNAFT--AFKACGKV-LYDRCFDKVGNFCFGVPEHIDFPGQKYDPCVGIYGRICICRPPEVTAVRP-IAKATLECYIFVCGAPGCGKCTFVCALAECYQGL-DK-IVKTMECPRDLQVGN---EITQYAPLEN------NMENTCDIL--------LLVRPDYTIYDEVRKTKDFEIFADMRMAGV-GMVGVVHACKPIDCIQRLIGRVELGIIPQI---VDTVIFIEDGKVGKVYEVEFNVKVPHGMKE--SDLAR-------PI-IEVVDF--ETKCPEY-EGRCGRKCTGA-KLRRIVK-KHKREMGNCPVETHLT--DCV-KIKILRGRGGCKKVKLERTNYANVFNQETKTCKKVTITNVIDNVANKHYIRRNVVTKGAIVETEMGKAKVTCRPGQDGIVNAILAGEIACKVRGEAQNMIKPGVKLYDVAEFVENRIR-ELGGEVA------FP--CNLCINDIAAHYTPFAGDECVFGENDVIKLDLGAHIDGFIADTATTLKKACEDALKTVINCIELPMNVGEMGKIICEVIECYNLKPICNLCGHVMHQNVLHAGVC-VPNGDLVAIEPFAT--DGFGAITDGNGKYILVEKERGMVCQCEHTVYMGEDKIEITTCQ-PRRCC-MECMKYCPICEQLCCG--CGICTKRCPFGCIKIIGLPEELCDDKIIHCYGQNRFRLYGLIC-PRNG-VTGILGPNGVGKCTIIKILNGELLPNKPQ-----YVDV---LPKVV--KGK-VGDMLKKVDET---G-KFDELTKELELTNLLNREFTQLCGGELQRVAIAAACLRDGCIYYFDEPTCWLDVKQRFCAAKVIRKVCE-----DKKVVAVEHDLIVLDYLCDNIHIMYGVP--SAYGVVTHPRGTRVGINAYLDG----FLKEENIRFRFKLNVEGGE-IYQGEVVGILGPNGIGKTTFVKALAG--VIKPNA------GY-------KPQYI-LTD---FDGTVEDLLLCGGELQRVCIAACLCHDADLYLIDEPCAFLDVEQRLNACRVIRRMADEKDAAMFVVDH--------D
Methanocorpusculum_labreanum_Z                          GAE-VYITGCNPLCT-----QDAKRGCNTEEYYAAIDKVLD-----AKPTLTIDDGMDLINRVHGACEETTTGIHRLKAMQAEGKLEFPVLCVNDTPMKHYFDNVHGTGECALACIMLTTNVLIAGKHVVVAGYGY-CGRGVATKARALGAR-VIVTEPRRALQAHFDGFDVM-SMNDADLFITTTGNCDIITDHHFPLLKCGAILANAGHFNNEICIPWLETH--ACCVEHRDG-IDT--------YLIGD--KKIHLLAEGRLVNLATPKGMGHPIEVMDLCFAVQVHDIPCEIDEYIARLKLAAVGATIDELCCGQKEYMCCWDIGGLGRELCLVREMIE-YPLRHPEVFEKLGIEPPKGVLLYGPPGTGKTLIARAVANEA-----GAYFDTICGPEIICKYYGDCEEKLREIFEKAEENAP------SIIFIDEIDCIAPKREECKGEVERRVVAQLLCLMDGLKCRG------KVIVIAATNLPDCIDPALRRGGRFDREIEIGVPDKDGRREILGADLALMVKEAAMHALRGPPGTGKTLLAKA---VANECECNFICVKGP--ELMCKWVDEIDCIVPRRGCYEGCCHVTECVVCQFLTELDG--LEELKNVVVIGATNRPDMIDPALLRPGRLEQGIAHIFACFNNTIITVTDLCGAETICKCCGGMVVKQARNECCPYAAMQMAINIAQACKDKGITGLHIRVRAPGNG-RQRCPGPGAQAAIRALCRAGMRIGRIEDVTPVPHDCIRAKGGRRGRRGCAGRFGPRYGRFCRKMVNECEKICRAKHLCPMCDT-IAVKRVGTGIWECRKCGYKYAGGAYVPVDMGAIPYMINGADVMRPGIVCVTDDVKAGQPAGKAAKNLHYIGDYGYVRDAWKKPAE-SGVKKLLWERMQTWRRQGAVVRLERPTRIDRARELGYKAKQGIIVVRACIRRGGRRKCRYIRGRRTNRMGMRKATP-GKNLQCIAEERAATRYPNMEVLNCYWVGQDGKCKYYEVILVDRNCPCVLADKNLAWVADT--RGRVFRGKTCAGRRARGLVIDIEHDPARHTPIAVVKIEGKACDKKEYALITEGVGIGQELGPEATVVNGNCLPLCAIPTGVAVCNIEARPGDGGKFVRCCGVQAMPCGKPKWFNEACLATVGLVAGGGRIDKPILKAGKQYHKMKTCATRWPRVRGVAMNVIDHPFGGGGHQH-PG--KPKTVAR-GACPGRKVGCVAARRNIGIVAHIDHGKTTLCDNLLAGAGMICE--ELCGKACWMDCDEEEQARGITIDACNVCMVHKVGDHE----YLINMIDTPGHVDFGGDVTRAMRAVDGAVVVVDAVEGPMPQTETVLRQALKEGVHPVLFINKVDRLINELKVNPQEMMIRLGKVIDKVNKLILDMVVTFLPNPLQAQGKRCHIIWHGDVECPIGKAMYACDCNGPVAMMITDICFDKHAG-EVATGRLFCGTLCRGQEVFICGTAGKPNRLQGVGIFMGPTRVEVDKIVAGNIAAVTGLCDAIVGCTECLKHYCEPVMTVAVEAKNMKDLPKLIEVLHQVGKEDPTVRININEETGEHLIAGMGELHLEVVTG-RIKRDKGVEIVTCPPIVVYRETVCKPLEGTVEGK------SPNRHNRFFMCVEPGIQYLNETMELIIDGIHEALDGGPLADEQVQNVLIKLHDVKLHEDAIHRGPGQVIPAVRGGMKAALLMAGDTLLEPMQKIQITVPQDQMGAAICQIQGRRGQLCTTECEGDQ-IVVNGEAPVAELFG-FAGDIRCATEGRAMWCTEFAGFCAVPNPIADAMCAIKNAGDTGKLAVTVEPACRLFGDMLKVMQEYGYITGFEKID-DGQ-FQIALCGG---INKCG-------VITPRFCVKVEDLEC---WEI-RYLP--GKGFGIIILTTCKGVMCHEQARKLGVGGELLGYVFGDGTIVLVGFPCVGKCTLLNKLTPGLI-AGAAMGKGRGKEVIA-VVRTADLG-------ENKIMNALQDAIYEHLGFVRIYMKPYGEEADMEEPFRY-----AKIGLKHVVED----NDMTTVFDIPADLLIAKVADELKNE-SVIKAPEWAEYVKTGVHKEMPPENP-D-WWYVRCAAVLRRIYVDG-PIGVERMRCVYGGLQD--RG--SKPCHFRKGCGCIARKVMQQLEEAGYLEKVTG---GRCVCAKGRKFLDNIADGENLLLGRLCCIVAGEE-IAIINAEKVIVCGARAMVLNEYQ-VKRVRGC----VEGGPFLPRRPDHLVKRTIRGMIPY-KTRPGGRATAGPPLGPALGPLGINVKAVVDDINKKTAEFN--GMCVP-VTVMV--DDKKNVTLTVGIPPTTALVMKEAGVEK------GCGTPNT-QAVGNLPLEAVIRIAKMKMECMLCYDLKTAAKEVMGTCVCVGVTVEGKTAKQAIAAVNAGKAGMTHVIMIDDHKKCPTEGKEVMVPVTVIEIPAMTVAAIRV-YVKDTYG--KHPLTEGTDVDMKCLLCEGQFADITGITKGKGFQGAVKRFGITLRK-RKHARTKKERH-IGTLGP-WTPHHVRWQVPMPGQMGFQQRTEFNGFLHYGLVRNNYVLIKGCIPGPAKRLVRIRCATRG-GIHPREAAQHHAFCIGPGLGPCLRIAATTARTLALKLGVPLIGVNHCVAHVEIGRWYT-----KFADP-IVLYACGANTQVLGFLN-GKYRI-FGETLDIGLGNALDKFARCHNLPHP----GGPIIEKMAK------DG---SYIHLPYTVKG-----MDLAFCGLMCETAFAMCVEVTERAGGVGANARLQEMLAKM-CEERGAKFMAPPRVYMGDNGAMIAYTGKIMLEAGRIRLTGTDYEKVETVCTRIREIAERTGVNMAGPIPLPTKRLIVPIRKCPDGEGTATWDRWQMRVHKRLIDL-DADERALRQLMRIQV---PKDICIEIIEFGILCPKAIRDMCVCKVIWPDTYDDDGF-PYPKGLMDPCL-GVIDPGLRCKTCGQKQGDC---PGHFGHIDLAKPVIHVGYTR----LIRKLLRVTCRDCPY-------CRERLEKIPD--DDR----PEWTVLTVLPVPPVTVRPCIILENGQRCEDDLTHKLVDIIRINQRFKENQDAGAPQLIIEDLWELLQYHVTTYLDNEVAGC------PPARHR-SGRPLKTLCQRLKGKDGRFRGCLCGKRVNFCARTVICPDPNLCIGEVGIPLAIANEMCVPVRVTKQNLEDMRALIRIGPHRPTL--RDPCGANYIDRQLRDGDIVLFNRQPCLHRMCIMCHHIKVMNGRTFRLNPAVCPYNADFDGDEMNLHVPQTEEARAEAELLVAV-QENILCPRFGGPII--GGLHDHICGIFLLTNKQAFCMILPDGFEQGHLEPMPGRTPEETLEMQVNCAVVMAVCGARGCMLNIAQMAGCIGQQAVR--------GERIVRGRTLPHFKRCDK-GADAHGFVRNCYKCGLNPTEFFFHAIGGREGLVDTAVRTCQCGYLQRRMINALQDMGE--VVVILKIMPECPDVDLEKLE-PIGFGLCAIKIAMITEDDE-GAGDKIEGLFCQIPGIVKGCKGELTRTMYHP-AITITIADGC----VTYKAHLGVMCKGVCEGYEYHMKIVYNHFPIQVKVAGDK--VEIGNFLGEKQARYANIV-E-GVKVKV---QG-DE-LILNGINRETIGNTAANVGVDEAGKGPVLGPMITAGVDCKKLCPKKRECLFEEIDAKYAVVGAACIVAKVTRDRCIADLKE---EYGGRARRPLIVVE---NGGKIEFIDAEEGIGAAHVPFPEHNACPRVTMGAGMIKQGFAQAN-MKLRPDTRGHMLHY-AQVPVHTQAAELIG--SDNRPQ--------GQNFCVAYEGYNIEDALIFNKACVERGVGRCHFFRTYEGEERRYPGGD-RIELP--EEDVQ--GCHGIGCYANLDV-DGIINPETVVRFL--EEPTGEL-IA--VEKRRDTCRCNETGIVDTVLVKVRTRDLRGDKFACRHGQKGVCGLITPQENMPFTANPHAVPCRMGHMLEMIGG-------KGREVMYDGITGRRFQADIYIGVIYYQKLYHMVCTKMHARCRGPVQVLTRQPTEGRAREGGLRFGEMERDVMIGHGAAMALKERLLDECDAVKQYVCAR--CGYAFKLLLDEMKCMGIAPRLDTGLFIEALTGFPGPYGRVDGEITDIPRGTD-GFGYDPIF-SV-------QG---RTLAEMNMHEKKTAIARATLREGKGRVRINEVYGN-EIIRMKICEADVDIDVCGGGVMGQAEAIRTALGRIKEVYLCYDRTLLVNDCRQKEAKK--PHGRGARARFQKCYR---------VYNERVWDPYRCKLLYLGAANGTTVCHVADYV---ECVYAVEFAPRVAQPDQAEIAVKHGRLI--LMLKT-----RCVDIRKCADEVFAD-TCAELVFYNTKMEFN--RDDRDEQAVKIIKYNDLDPFGTPVPFLDAACRA-AKH--YLFVTATDTAPLCGAHFKAGCRRYFATPR-NTEYHAEVGLRMMMGTMARELVKYDRGMK--PILCYAKCHYFRCHVRVLGKVTAADETLA-QIGFTGKPGIGKTCAALALAMKEICRFE-------DIACGEDALCAIAECCAGDMRTAVNMLDAGMVRYVTITCTEVPCCCGRLTQQQFTKCEMAIVERLINRLMGKKMMCTKMVMDAFDVINKKTKQNPLQVLVDAVANAGPREETVRLKYGGINVPKCVDCAPIRRVNTALRYIALATWKGC-HKTKKPAYLVLADELIMAAKGD-AK-CFCVGKKEEVERIAKCARRG-TRTCGGGTHKNRRGAGNRGGRGAAGW---RDHNFTRWYLLGKTE-------G--KHGFKILGGGKVTHKLAITAENFCGRAVAKIEELGGGYNIEQLK------AMCMDELLAIMPCGARRKVLR----GVRTHCRCMIILPEMVGKNVAIYCGKEFINVEIPVEGVFHYFGEFALTRKKVTHGCAGIGATKCCKYVPLKADNTGARVVQIVCVFG-Y-HGVKNRQPKMGLGDLATVTVKKGTPD---MKRKLVRAVVVRQKKEFRRPNGLRVCFEENAMILLNEN-GD-PRGTDIKGPVAREVAER-FPKVGCMARIAACVLGCGENRVWF--NPEKLCDIQNAMCREDIRNLIDEGAICCHQKKGICRGRVRARMVKRC-YGHGKGPGRRCGAKGART-PCKTQWIKKIRAQRKELRAQREAGC-ITPTEYRRLYRRAAGGQFRNVAHMWVPVTGLGKKVMAGEFACFDEILACGQPIKEAGIVDAML-PDLGRRIKFRAVVVIGNKNGYVGFGQGRDVQVGTAIKKAITNAKLNIVKVRRGCGCWECGCGMKHCVPMEVTGKAGCVAVTLKPAPKGIGLVTGDVGKKVLTLAGIQDVWVNTCG-----NTRTTLNFAKATYNALQYLNKELKRAGYGGMDIVRT-PVGTQVTIFAEKPGIVIGKGGKLVRQLTTDLCTVYG-IECPQVEVQQV---ANPNLNAQIMAERLANALERGWY-FRKAGTCVIRRVMDC-GALGCEVIIAGKLTG-ARARVQKFVEGYIKHCGEPCECIVEKGYATAIKKLGIIGVQVKIVPP--GAKLPDLMQVMEPEARERLNTIRLTKPEFAACVEQQIVCLAQCGRLRQKITDEQLRQLLHCGTLDPMVCGVLVVMLGKAVRLAPLLLQHEKEYFTGRVYQRPPRRCAVRALRIRVIYRIEL--IGTYIRCVCVHIGNVLGCGGQMIELRRTKCGGFCCDEA--HTLPPEQAIGDIPKIVIRDKAAKAVANGAMLAGVGVALITQCGKLIPAVKPPEGHVHFKNKL-MWTAAVLLLYFILTNIPVFGG--TILHLGIGPIVTACIVLQLLRGA--DLIKINTCD-QRGQVLYMGLQKQICI-GGVLVMFMDEVVCKG-----IGCGVGLFIVAGVTVGLFFIIVYVECTRIEIPPVKLVYACVLPMIFAIF--WVKTAGLDC-KHVARQIQNCGMQIPGYRRCPAVLERYLDRYIPRVTVIGGVFIGLLCVMANML---GIIGFV-----GGTGLLLTVCIIYRLYEQIANEQMMEMYPLIQYKAVEFGD---FTLACGAQCYIDVKTAIMQPP--C--AVIRAAAKGKCQM--IIG-NVK---GQRVLLIEDVTTCGGCCKYGVEELRKAGGKFAARNLVRTAKKFRWCDCVYCRRAL-KLKLKADPLEGA------PIGRAIVLEKVGVEAKQPNCAIRKVRVQLIKNGRQVTAFAVGDGAINFIDEHDEVTICGIGGRAG-RCMGDIPGVRFVVCG--VNGVCLNELVIGR----AEKARRLVCVEEYL-----AAGVHIGTQQK--DNDMKD--FIYRVRC-DGLYIIDIRKTDERIKQVAKFLARY--EPAKIFVVTCRQYGQYPAQKFADTIGALCHVGRFIPGTLTNPKLPKYVE--------PCVVIVTDPIGDAQVITEAVQCGMPVIALCDINNRTNNVDLVIPTNNKGRKALCMVYFLLTK-EF---LRQKKQCLILRCDLKLCCGKMCAQAAHAWLREGQKKVALKAPCERALYELKVVAEMHGVPVCLIVDAGYTEIPPGTVTALGIGPAKAEIINKITGHLPLKYVVVTGGVMCGLGKGITAACIGRILINRGYHVTCVKIDPYLNIDAGLMNPAQHGEVFVLKD--------G-----GEADLDLGNYERFLDIELTCDHNLTTGKIYCCVICKERHGDYLGATVQIIPHITDEIKDRIEICIVEVGGTVGDIECMPFLEAVRQMHWEYGNGDFALVHVTLLP-ADTMGDLKTKPTQHCIKALRELGLEADIIVGRCNLPVCLCTKRKICCFCDVDVHAVICAQTAPDTYLVPMELEKEGVEDVYICIKEALKHDGILIPGGFGNRGIEGMICAIQYAREHKKPLLGLCLGFQLCVIEFMRNVVGYWDATCEEMGAGTH--AQEGV----EDLGGTMRLGDYPVTLDPACRLAELY-GATEIVERHRHRYEVNPT-YIDEIEAKG-----MKFV----G---KNGRRMEALEL--AD--HPYFVATQFHPEFRCRPARPCAPFRKFQECIDITINLKHVDMAQ-PKNRIDETILLPQAIG--VKKIAVLGKGDIVCQARNAGVDLIIGPDEIERLGGVPREARKMAGQYDFFLAETAVMPLVGRWL-GQRLGPRGKMPVKIRCKDRLNMCVKVGNTGMTVEEVCENIDAVVKRVVGRLECGEL--NIRCVYVKTTMGMGYPGKN-TKQYCC--PKRRFEKCRIECERVLAITYGLR---NKREIWRATEVLRKH-RC--GAREVLQRYGLL---GPDAAMDNILCLKVEDILERRLQTIVYRKGLARCPKQARQLITHGHIAINGQRVCVPCYMVCIAEEAGILAHPLVTEKAMVLLENCNQLCFIVEKEAGKACIKAAMEKNFGKKIVCINTKKAVITFEEKN--AAEEILCQLGVKAINGCVLHEIEL-PAVFDEAYRPDLIKRAILAYQCEQYQPHGADPYAGMRTCA------EGWGC--KRGEAKIP-R--IKNGC-----R-AAKVPNVKGGHPAHAPKAEKILVEKINKKEKAKAIRCAIAATVNTELVTARGHKFEG--EA--AIIVDDCFEQ-IAKTAEVKLALVALGLGADLERARLCR-NIRAGRGKTRGRKYKQAKCALIVNIAGVDCVCVNALNINVLAPGADAGRLTVWTEAAARLETHGLKFELLVDPELADKMR--HGE-D-LDIEDVVAAMYVYENACRGDKCPDEDLIKAFKTTDFTEIAKHIILKGEIHLTTEQRRHLIEEKRRRVITFIARNAVNPQ-TGLPHPVMRIEMALDQVRINYDPFKCVDDLVKEAVKALRPILPIRFEERRIAAKFPMDFAARAYAAICGAAYVTMDKNEWQNDGCWICVV-TIPAGMQEEFFNLANAAAKGICPIKNGTVIDHITPGEG--------LTVLRILGIR---DGTNVTVIVACNVPCCRGG-R-KDMVKIENRELLKDEVDKIALVAPDATICIIRNFKVCVKKPVEVPKQIIGV--IKCPNPNCITNTK--EPVQCRFVVH-----PRGFRCQYCTNPRLECLIMMLKRACRENEANIWREIAGRLNTCCKNQA--EVNVGKINRYANEN-----EIILVPGKVLAAGVIGTC-VCVAALNFCDAAREKITEAKGTC--MTIEELVA--ANPKGCRVRIPVRCFTCGKVICTVWEEYQQRK--AAGE---DP-----KEILDCLGLDRYCCRRMLLCHLKEGRYVVV------DDEPCKIQCICICKPGKHGAAKARLDVVGLFDGQKRCVVCPTCATVYAPIVERKTGQITFMDMKDFNNAQEVPYIEC-LGKRKLKYLIHIHIEAEGVVDV-----VGAFGQTEGLLGEEL----DLRDLQRCGRIGRIA---AALETIDR--------IGPCMAAIRIQNIEDLRAIKRRQIVERAVLECDAIIIVEGRAD------VLNLLK--CGINNTVAGTK--VPETVIDLCAKKNT--TVFVDGD--------RGGDL------ILRELLQV-ADID---FVAFCPRRR-SVEDMCRKE----IVKCLDQAFAK--GLTYVAANAFE-GI-VRRPMQTPFVAKVVVHMGVGEA---GERLVNAENIMADLTKGAKPIRCYARNTLPAFGIRKGQPIGCKATLRGKKAMDFL-EMALKTYAV---ENV-LHTRQFDATGNFGFGIEEHTDFPGQAYDPKIGIYGRITTTRPPEVTVVRP-TREVCFECYMLIVGTPGCGKCTLEQNIAIYLGCQ-NF-IVKTIECPRDLMVPD---SITQYTCLDG------SIAATGEVL--------TLLRPDYVIFDEMRRCEELCVFADLRLCGI-KVIGGLHAKCALDAMIRLACLVDLNLIPQI---VATMVFVKTGDICEIYNVCTGFGVPKALEQIGDPQIR-------PI-VRLTNI--ITQETAA-EGKCVRKATGG-RYHACRG-KKRFEIGRCPADTIIG--TT--RVKTIRVTGGNTKVRALRCEFANVCDKKTGKVQKVKINCVAENAANPNYVRRNLMTKGAIITTELGKAQIVCRPGQDGVINAVLAGRIAKNVLHKCAAEIKPGVGMADIFDMVLDEIC-SAGVCPC------FP--PNICLNNCAAHDTACPDEERVFAEGDLIKLDIGTHIDGYIADTAVTLCEACRAALDAAINVVAPEVVVCEIGAVVEETITCFGYKPIINLTGHALARYCLHHGLC-IPNDMVIAIEPFAC--TGCGLVHEAPRAEILCDVPECFVCQFEHTVIVTADGALVTTCH-AKKCG-KECIAYCPICEELCVG--CGICVKKCPFEALDIIQLPEELDT--PVTRYGPNAFVLYGLPQ-PVAGKVTGMLGPNGIGKCTAVKILCGQMKPNKPQ-----YIDF---IPKAF--KGT-VRCLLEQNDER---K-KLDYYAKELALDTILDKDLTYLCGGELQRVALTVALCKEANFYFLDEVTPFLDIYQRMTAARLIRELAC-----EHPVILVEHDIAILDMVAETVHIGYGKP--SAFGIICRPKGVRVGVNQYLEG----FVAEENVRIRFDLTVDGGE-VRRGEVLGIVGANGIGKCTFAKLLAG--VETPDG------GY-------KPQYV-TAD---SCDCVEFTLLCGGELQRVAIALCLCREADLYILDEPCAHLDVEQRLVTTKVIKRAAEDKGAGIMVIDH--------D
Methanopyrus_kandleri_Av19                              GAE-VAITGCNPLCT-----KDAWRGETEEEYYQNIDRVLC-----HEPDIIVDDGADCIARVHGATEETTTGVNRLHAMHREGVLKFPVIAVNDAKTKYLMDNRYGTGQCALDGLMRATNILLAGKTVVVVGYGW-CGRGIARRARGLGAN-VIVVEPIKAMEAIFDGFRVM-PMDRADIFITATGNRDVIRGEHIEKMKDGVILANAGHFDVEIDKEYLEEH-CEEKIDRRGGLVTE--------YRMPD-GKRVYLIAEGRLVNLAA--GEGHPIEIMDICFALQVYKVPKDVDKRVAELKLECMGIELEELTPEQREYMKCWDIGGLDREIELIREYVE-LPLKRPELLKELGIKPPKGVLLYGPPGTGKTLLAKAVANEC-----GAKFYCINGPEIMCKYYGECEARIREVFEEARKNAP------AIIYIDEIDAIAPKRGE-TGEVERRVVAQLLTLMDGLCEDE------RVVVLACTNRPDDIDPALRRPGRFDKEIEIGVPDKEGRKEILGADLEALCKCAGLKALRGPPGTGKTLLAKA---VANECDANFIAVRGP--EVLCKWVDEIDAIAPKRGTEVGGCRVTERIVNQLLTEMDG--IEATEDVFVIAATNRPDIIDEALLRPGRFDRGIAHIYACFNNTIITITDLTGAETFARWCGGMVVDADREECCPYAAMKAARRAAEEAMEKGITAVHVKVRAPGGH-GPKTPGPGAQAAIRALARAGLKIGRIEDVTPIPHDGTRRPGGKRGRRGPAGRFGPRYGMRIRRRVAEIECVQRQKHECPVCHK-RAVKRVGTGIWRCTKCGAEFTGGAYYPVDMGAVKPVACGADIMVPGIVEVRGEFEEGDGVGRAVRNVHHVGDYKYQREAWKRPKD-SYVGELLKERLPKWRKGPCVQRIKRPTRIERARRLGYRAKPGYVVVRVRVPKGGRRKCRPKKGRRPKRMGKNKFCP-GKCKQWIAEERAQRKYPNLEVLNCYWVGEDGQYKYYEVIMVDPYHPQIKCDHRINWICQKCQKGRVFRGKTGAGKKARGLVVELLHDPARNAPVARVRFE---DGEERLILVPEGTKVGDIIGVCAEIKPGNTLPLAEIPEGVPIFNIEGQPGDGGKFARAPGCYALPCGKVRTFDPRCRATIGVMCGGGKREKPFVKAGKKYYHMRCKGGKWPKVRGVAMNAVDHPFGGGNHQC-PG--KPTTIAR-GDPPGRKVGHIAAR????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DPLADAMATIKNNEMVGNKECVIEPACKLIGRVLKVMQEYGYIGCFEFID-DGK-FLVKLVGR---INDCG-------VIKPRHPVKKDEWEY---WEQ-RYLP--ARDFGLLIVTTPEGVMCHYEAKERGIGGRLLAYVYGAAQVALVGPPNAGKCALLRELTPPIY-EG--FTRGDGCKFVG-VIRNADLR-------DAGIHCAFKRRLYDTLGIIRVYTKKPGGKPQ-KPPLKY-----ARVGRDHVLED----GDVYDAYVVPGCELVERLAEKLK-DFEEIKPPEWAKYVKTGRHKERPPEDP-D-WWYMRAACILRRVYMDG-PVGVCRLRTYYGGRQD--RG--ARPERFRKGCGAIIRKILQQLEEAGLVEKTEE---GRVVTPEGRCLVDCTADAENAVLGRLACVVAGER-IAVINTEKAIITGKKNTIKEEWL-QKIQRGD----PKKGPFYPRRPDLIFRRVVRGMLPW-KTKRGGKADPGPPLGPALGPLGVNIQEVVEEINRKTKDFK--GMEVP-VKIIV-DTETREFEVKVGCPPTCAIIKCELGIDK------GAHEPRH-ETVGDLCMEQVIKIAKMKFDDLLCYDLKTAAKEILGTCGCMGVTVEGKDPKEVQKEIDEGKAGMTHAIMIDDWPNCPTEGEEICVPVTILDAPPMYVAAIRA-YAPTPDG--YRCVTECEEIRAKDVFDEGEIVDVCAITKGKGFQGVVKRWGVTIQD-RKTQRKQKGRH-IGCIGP-ITPCRVRWTVPMAGQVGYHQRTEHNGFVNYGVVRGDYIMIHGTVPGPKKRLIRVRPAVRGCGILPREAAEHHAYCQGPGLGPCLRVGATAARTLALTLEVPLAPVNHCVAHVEIGKLAARQDGFDFDEP-VTLYVCGGNTQVLALKA-GRYRV-FGETLDLPVGNMLDTFARKVGLPHP----GGPEIERLAE------EG---EPVELPYTVRG-----TDVCFCGLLTETAFAMLVEITERAGGVAANRRLCEMMHEM-AEDRGAEAYTVPPELAGDNGAMIAWTGILVHEHGRLRLCCTDHYKLEEVCERIKKVVEETGAQMCGPIPLPTKRLLVPTRKCPDGEGKATWDKWEMRIHKRLIDI-KGDERTIRRLMRIHI---PEEVHVEIILFGILPPDKIRKMCKVEVTCPETYDEDGY-PIEGGVMDTRM-GVIDPGLRCRTCGQPAGRC---PGHFGHIELARPVLHPRYAE----RIKDVLRATCPECPH-------CRAWLEKIPD--EDR----PEWAVLTVLPVPPVTMRPCIILETGERAEDDLTHKLVDIVRVNLRLKECLEAGAPEPIIEDQWDLLQYHVTTYIDNEIGGV------PVARHRTGGKPLKGIVQRLKGKEGRFRQNLAGKRVNFCARCVITPDPELDPFTLGVPEAIAKELTVPERVTEWNIDRLRKLVLNGPNKHP-------GANYVERHLMDGDPVMFNRQPTLHIQCELGFRVRVMPGKTFRL-PAACGFNADFDGDEMNLHVPQCEEARAEVRELMGCYVYHLWPPKNGHEDVRNCPIHEAIVGIHLLCGRQLLCVFLPDGETCNRCRIERGEMLERNIECEVNPAYIMPECGARGCITNIARMALIGGQQAVM--------GERPHRARVTPHFEKCLIPGVKEGGFVRCGFFEGLDMVEYFLHAMCGREGLIDKGFRTADCGYLHRRYVTTALDVCK--VLVDLKVLPECADVDYEELE-PIAFGLKAIRVKVVVPDAE-GGTDALEDALKEVDEVVKGPKGEVTKEFYYP-DVYLWVEDDE----VMIKAYIENMQKGVTEGHEYKLKLVYCHFPPEVKVDQKEGKVYIENFMGENVPRVAEIVDPENTEVIV---QG-QD-IIVRGIDKEAVGQTAANLGIDEAGRGPVFGPMVVAGVDCKELTRCARRRLIRALDAKYEVVCAACIVAKTYRDWIVRLLEL---EYGGRVVRPLLVVE---DGGVIEFLDAEEGTCCCCIPWPECNCAPRNTMGTNMTRQGFYAAN-HPIRMECRGHLLYY-PHRPVKTRGTEAFD--YDERPA--------GQNMIVAYEGYNMEDAIIMNECAIERGLARCFFFKTFEDEARTYPGGD-KFCIP--EKEVR--GYRCEDAYKHLGE-DGLAEVGERVRFL--EEFRPEE-LP--AEERRECCRHTDCGIVDCVLVKVRIRDERGDKFCCRHGQKGVIGMIVPEEDMPFTENPHALPCREAHILETLAG-------KGKEVMYDGRTGQKLEAEVFIGVCLYRKLYHMVKDKYHARCRGPVQVLTRQPTEGRAREGGLRFGEMERDDLVAWGACLFLKERLLDECDKYEAYICPN--CGYAFKILLDELKCFCMDAVLDCGLFIEALNGFPGPYGEIRGRIAEEPRGEE-GFGYDPIF-IP-------EGED-STFAELGVEEKKTAIARAVIREGEGRVRVNNIIEP-EMARMKIMEPDIDVKVQGGGWMCQAEAARIAIARLRDAYMAYDRHMLKGDPRRKEPKK--FGGRGARARRQKCYRTENLVPGHQVYGERVWEPRRCKLLYLGAAAGTTPCHVCDIIKECGVEYCVEFACRIAQPKQAEVVADNGYVI--VAIKA-----RCIDVTKEPEEVFED-EERKLVFYNPAMQLC--RDDLNPRAVELIEENDIDPFGPPVPFLDAAVRT-VRNRGVVGICATDVCALAGRYPRCARRKYWVEVE-RVEFYQEVAIRALICYIVRTCAKYDLAFE--PHIAFFQRHHVRVIGEIRRGARRADRALK-RLGLHGPPGTGKTCAAYALALRRICERE-------GIEYEEVALRRIAKRARGDLRAAINDLDPGLKDYICLKPMYLPHTGGRHAKKRFAKAEVPIVERLINRVMGKKHLAYNIVKRAFDIIHERTGENPIQVLVQALENAAPREETTTIIYGGICYHEAVDCCPQRRLDIALRLITEGAQQRA-FRNPKPIEECLAEEIIAAARYD-TE-CHCIRRKEEIERIAEAARRG-SRTHGGGCHKNRRGAGNRGGRGMAGC---HKHKWF-HVIKYMPD-----HFG--KRGFKVLGGGHVKRPLVVVAPEFTERAVEKLEEAGGGYTLGELM------KMPIEEFIELLPARQRRCLKR----GIRTHCRDMIILPEMVGLTIAVYNGKEFKEVKIEPEMIGHYLGEFAKTRKTVEHG--GIGATRCCLFVPLKADNTGARELQIIAVKG-Y-KGVRRRLPNAGIGDMVVCCVKEGTPD---MRKEVVNAVIVRQRKEYRRPDGTRVKFEDNAAVIVTPD-GA-PRGCEIRGPVAKEAAER-WPRIGCIARMAAEILKCGVHRIWI--DPERLEEVARAQTREDIRRLIKEGAIRKKPIKGQCRVRARKRHEQRK-KGRQRGPGRRKGAKGARM-PKKRAWIQRIRPIRRKLRELRDCGK-IDRCTYRKLYMMAKGGYFRDTCHLWEPKTKLGRMVKEGEIKTIDEVFAQGWKILEPEIVDWLL-PDLGRRVRFRVTVVVGNKDGFVGVGQGKAREVGPAIRAAIDRAKLNIIKVRRGCGCWECGCGRPHCIPFEITGKCGCVRITLKPAPRGTGLVAGETAQKVLEMAGIEDVWTKTTGGKGKGETRTTINFAKATFDALEYLEEELGRAGYGGMRLQRV-PNATKIIAYVERPAIAIGRRGRNIRRVEEEVQERFPLLGRVCIEVKEL---PCPELNPRVVARRLACALERGIH-FRRAAYGALRRIMNA-GAKGAMIILCGKLIG-ARARTEKFMEGAVKYCGEPGDEYMIEGYVQAVTKPGAIGVTVRIMPP--DVELPDLRRILTPEARERLARVRLARPQLAQAVENYLLQLAQTGQLKEKIDEDQLKRILHGGTLDPKVTGVLPIALEKATKIIQTLLPAGKEYFEGTILQRPPLRCAVRRVRPKKIYYIDI--LGTYIRKLCHDIGEALGVGAHMAELRRTRTGPFCEENA--VTLPMEEGLEHLPRIEIRDTAVDAICHGANLAAPGVAIFTLKGEAVPEVKVPDRHVPFNEKLFKYTGIPLILYFILCEIPLYGG--SILTLGIGPIVTACILLQLLVGG--DLIKLDLTN-PEDRRLFQGLQKQLAL-GGILVIFLDEVVCKG-----IGCGVGLFIVAGVAIITFLIVLYVEGMRVEIPPVRLLYTCNIPVIFAVL--WVELTGMGP-REIARHLHRAGLHIPGFRRDIRVLEKRLQKYIYPVTVMGGAFVGFLAAGADLM---GALG-------GGTGVLLTVCILYNMYEEIKQERLMEAHPLLEVGALKFGD---FVLCCGKRCYVDIKEACTHPP--M--AIVRKRKKGTGER--IVG-DVR---GRKVVLVDDVATTGGCLLEALEAIEEEGGEFAARKLREKRKKFRWKDERYKRRML-KLDEKADPLEGA------PQARGIVLEKVGVEAKQPNCAIRKVRVQLIKNGKQVTAFCPGDGAIDYIDEHDEVVIEGIGGPKG-RAKGDIPGVRYKVVK--VNDVALCELLKGK----IEKPMRLVPLNDYL-----AAGVHIGTQQK--TKDMEP--FIYRTRA-DGLHVIDVRKTDERIRIAANFLCMY--NTDEILVVCRRYYGQKPVCKFAEATGTTAIPGRFVPGTLTNPEYDGYLE--------PEVIVLTDPRADFQALVEAQCVGIPIVALCDTDNFTGNVDLAIPTNNKGRKALALVYWLLAR-EL---LKKLKQVIVVRGDLKLCRGKLAAQVAHAWLREGQKKVVLKCKDKEELLELHELAKRRGLPCFLVRDAGLTELEPGTVTCLGIGPEREEEIDRVTGDLPLKFVVITGGVVCGIGKGITTACIGRILRARELEVTAVKIDPYINVDAGTMNPFQHGEVFVTED--------G-----VETDLDLGHYERFMDVTLCGAHNITTGKIYQRVIEKERRGDYLGETVQVIPHITDEIKCWIDVVLVEIGGTVGDIEGMPFYEAVRQLQLEEGRENVMFVHLTYVPYLEHVHELKTKPTQHCVKELRCLGIQPDAIVCRCERPLDDGVKRKIALHTNVPREAVIDAHDVDLVYKVPLLLERQGLPDAYICIREALVHDGVLVPGGFGKRGVEGKIEAVRYARENDVPFLGICLGFQLVVVEYARCVLGLEDAHCTEFNPDTDHPVQRGV----KRKGGTMRLGAEPVVLEEGCLLRRLYDDREIVLERHRHRYEVNPC-YVRELEDHG-----LRFC----GHC-PDG-RMEALEL--PD--HPYFVGTQFHPEFKCRPGDPCPPFRRFLETVDMIVNVKGVDLCD-PCQRIDKEVVLPHGRG-KPVNVCVIAEGEMAREAEEAGAT-VINREKLEELAENVREAKKIARRHEFFYAQVDLMPDVGRVL-GPVLGPRGKMAARVRMRDQPVIHTVIGARNMEPEQLAENAMAVLREITCELEKCWA--QIDCVYVKTTMGMGDPKRP-RKKYET--PRHPWEAERLEYERKLMRKYGLR---RKKELWRHQTQLKRW-RE--RAKELLYDLGILDKKPEEATLDDILRLTVEDVLERRLQTIVYRKGLAKTPLQARQLVVHRHIAIGDRIVTVPCYLVCREEEEEVLLYPVATEKAMRLMEAENKLTFIVRRDANKPLIKKAVEELFDVEVEKVNTKKAYVKLKPEY--RAEDVAVDLGVFNLEGEEVDTVEL-PCFFEEPVRKDLIRRAVLAAQANRRQPYGTDPRAGFRTCA------ECWGA--GHGVAMVP-R--VKGRRHPAAGR-AARVAQAVGGQKAHAPTPEKDWTQRVNRKERRAALRCALAATAKPEFVKERGHVIDDVPHL--PVVVVDELKC-LNKAREVREFFKCVGLWADVERAKCNR-RIRAGKGKRRGRRYVKPKCVLIVNHPGVDVVEAMHLGVEHLAPGAHPGRLTVFTPGAARLEKGGERFEVLVDPEGARKFR--EGE-D-VDVEEILAVEQVFRDARKGERACEQAMEELFGTCDPIKVAEIVIKEGEIQLTAEQRRRMQEEVKRKIIHIIARRAVDPR-TGAPHPPERIERAMEEAGVHIDPMKCAEEQVKDVIKQLRPVLPMKFEEVKVAIRIPAKYTGQAMGVVREFG--DIEREEWQYDGAWVAVV-RLPAGLQDEFFEKLNEITKGVKRIEMGTVLDHLPPGTA--------PQIMRILDID--PTETT--LLVAINVECCKMG-R-KDILKIEGKILCEEEANKVALVAPNATVNIVRDYCVAEKFQVKPPERVEGF--LRCPNPNCITNDER-EPVDTVFVRE-SKK-PLEYRCRYCTNVELRKLIRDLKKAACEYNAPVWRDVAERLCRPRRQRA--EVNVGKLDGLARRGVIQEEETVLVPGKVLGDGVITQP-LRVAAWRFCRTARMKIEAAGGEC--LTIRELLE--ENPEGCYIRIPIRCFTCGRPIAHLWEKYVELI-EEEGM---EP-----GEALDELGVDRYCCRRMFLCHLKKGKYIMI------DDEPCKIVEYTTCCPGKHGCAKARIVAVGLFDGKKRTLTKPVDAKVDVPVIERKTAQVQLMDMETYETGTMVEYMEA-AGKRKIKYVIRAKLRANGYVDV-----VGAFGQTEGLLGDDL----DLRRLLKTGRIGRIA---AALEQVDR--------IGPCRAEVEVVCIDDIRKEKRERMIRRAVEDCDAIIVVEGRAD------VANLLR--CGIKNVIAGTN--VPEAIVELCKEKTV--TAFVDGD--------RGGEL------ILKELLQV-ADVD---YVAKAPKGK-EVEELTRKE----IKRALEAAREK--GVKYVVGVKEG-DLDPEIKMRKPRVGKVTVNIGVGEC---GDRLQKAYELLQELT-GQKPVYTRAKQTNPCFGIRRGQPIGVKVDLRREQAIEFL-DWTLD--AV---DRE-LHECQFDEFGNVCFGLEEHIALEGVEYDPEIGIFGRICIARPPEITAVRP-VVKVCLDDYILVAGPPGCGKCTFCAALAEFYAEQ-GK-IVKTMECPRDLQVGD---EITQYAPLDG------DMEKTADIL--------LLVRPDYTIYDEVRKTKDFEVFADMRLAGV-GMIGVVHATRPIDAIQRLIGRVELGVIPQV---VDTVIFIEDGEIKKVYDVCLTVKVPTGMTE--EDLAR-------PV-VEIRDF--ETGELEY-EGRCLRKPTGG-RIRPHRK-KRKFEMGNPPTETLVG--EER-KLKERRGMGGNVKKGLKFATHANVADPETGEVKCVRIEEVVKNPACQYYERHGVITKGAIIRTEIGLAKVTNRPGQEPVVNAVLAGKVVKRVLRRAAREIDIGDRLLEIAEYLEECVR-DQGAEPA------FP--VNLCLNEVAAHYTPCPDDEVEVCPGDILKVDIGAHVNGAIGDAAITLAEAAREALEAAIETIRPGVECREVGRAIGEVCRDRGFKPVIGLTGHQIEPWNLHAGVC-IPNGMVLAVEPFVTTEDGEGDVKPGCTVEILVEVNGEPVAQWEHTVVVTERGCRVLTCKGGCKCD-YVCQRFCPICEELCCG--CGICAQKCPFDAIKVVRLPEELEEE-CVHKYEEGGFRLYRLPV-PKPGKVTGVIGRNAIGKTTAAKILTGELKPNKPQ-----YVEA---LPKVV--KGR-VKDVLEDVDEL---G-VVDELIERLGLTEVTDRRICDLCGGELQRVAIAAALCRDADFLVFDEPCCYLDVEQRLCLARCLREIVE-D--RGIPMLVIEHDLATLDYVADVVHVLYGKR--GAYGVVCKPMGVGKGINAYLKG----YLEAENVRFRFRLEVEPGE-IRVGEIIGALGPNAIGKTTFVKLLAG--VLEPTG------GY-------KPQYL-EVD---SDEPVEQVLLCGGELQRVAVAAALCREADLYLLDEPCAYLDVEERINTARVIRRVIEARDAAAIVVDH--------D
Methanosaeta_thermophila_strain_PT                      GAE-IALTGCNPLCT-----QDAFRGENECEYYECIERALE-----LRPNVTLDDGADTIAVVHGGCEETTTGVMRLRAMADDGALAYPVIAVNDAETKMMFDNRYGTGQCTLHGIMNATNFLFAGKTVVVAGYGW-CGRGFAMRAKGLGAN-VIVVEPRKALEAAMDGYRVM-SMRCADLFVTLTGDINVIRNEHFELMKDQVILANCGHFNVEIDIPGLECM-AVCTDEIQPN-VKE--------YVMPD-GRRIYLLAEGRLINLAA--AYGHPPEVMDMCFANQVYPVPVEIDRRVAELKLKAMGIEIERLTPEQDRYLHCWCVGGLRAEVQRVREMIE-LPMKHPEVFRKLGIDPPKGVLLYGPPGTGKTLIAKAVANEC-----GACFFCIAGPEIMCKYYGECEQRLREIFEEANCNTP------SIVFIDELDCIAPKRCEVTGEVERRVVAQLLAMMDGLKERG------QLVVIGATNRIDAIDPALRRPGRFDREIEIGVPDRDDRVEILGADIAALCKEAAMKALRGPPGTGKTLIAQA---VANETNANFICVRGP--QLLCKWVDELDAIAPMRGMDEG-ARVTERVVNQLLAEMDG--LEDLKNVIVIGATNRPDMIDPALLRCGRFDRAIAHIYCCFNNTLITITDLTGAETIAKICGGMVVKAARDECCPYTAMQMAMQVAEQAKAKGIVGVHVKVRAPGGN-KQRCPGPGAQAAIRALARAGLRIGRIEDVTPIPHDGTKPKGGKRGRRRCAARFGPRYGRKIRKLVADIEEKCRVRYDCPRCNR-TRVRRVGTAIWQCCKCGYEFAGGTYLPVDCGAVRFIANGADVMGPGIVQADPEIQTGDLVGKAVECIHHVGDYGYIKDAWNCPAK-SYVGRLRAQRMIAWRREMCVQRIERPTRLDRARALGYKAKQGIVLARVRVRRGALRKCRYVRNRRTKHMAMHRQNP-GKCLQRIAEERACRRFRNMEVLNCYWVGQDGRHKWFEVILVDPNHPAIKCDRDLCWICGGCHRGRAERGKTCAGKKGRGLVEDIMHDPARTAPVALVRLE---NGEKQYVLATEGTYIGQEIGPAAEIQPGNTLPLACIPEGMPICNIECKPGHGGQFARACGVYGLPCGEMKWLNPNCLATIGVVAGGGRTEKPLVKAGKCFYKYRCKAVKWPRVRGVAMNAVDHPFGGGGRQH-PG--RPKTVCR-GTPPGRKVGCIAARRNIGIVAHIDHGKTTLCDNLLAGAGMICM--ELAGKQLFMDFDPLEQARGITIDAANVCMVHEYEGKE----YLINMIDTPGHVDFGGDVTRAMRAVDGAVVVVDAVEGAMPQTETVLRQALREGVRPVLFVNKVDRMINELKVEKKEMAIRLGRVIDNINKLINDMIIRFLPCPLEAQKNRIRVIWKGDWNCPVGKAMTACDPNGPVAFMVTKIKVDPHAG-EVATGRLFCGTLVRGMELHICGV-PHTNRIQQTGIMMGAERIEVERIPAGNIAAVTGLRDAIVGCTEIIKHVCEPVMTVAVEAKNMRDLPKLIEVLRQTAKEDPTLQITINEETGEHLMAGMGELHLEIVAT-RIQRDKGVEIKTCPPIVVYRECVTGKC-GPVEGK------SPNHHNRFYIEIEPGIQYLRETMELILEGFEEAITAGPICREPVQGIKAKLVDVKLHEDAVHRGPAQVIPAVRQAVQAGILMANPTLLEPMQYVFIQVPQDQMGGAMCEIQGRRGVILCMETEGDM-ITIKAKMPVAEMFG-FAGAIRCATEGRALWCTEFAGFEPIPDPLADAMCTIKNAENVGKPECIIKPACKLIAMTLKVMADLGYIGEFEFID-DGM-FKVKLLGR---INRCG-------VIKPRFAIKVAELEK---WER-RFLP--ARNFGVLILCTCQGVMPHTDARARGIGGHLLAYVYGDATVTLVGPVGAGKCTLVCRLTPDIT---------VCGDALC-AVRDCDLR-------EYKIHCALKDEIFERLDLIRIFMKPQGKPPDLDEPFRY-----ATVGLDHILCD----GDLTTVYDVPPADLINAVAEELK-ACGKITPPAWAAYVKTGVHTEMPPCNA-D-WWYVRCACVLRHVYVDG-PVGVCRLRTHYGGKTK--NR--VVTGRTVKGCGCIIREALQQLEKAGYVKKQKD---GRHITPEGQAFLDNIADATGLVMGRLACITAGEE-IRIVNAEKAIICGCKECVLREYR-EMLERGT----REKGPYYPKRPDRILKRTVRGMLPY-KTCRGGKATAGPPLGPALGPLGVNVAAVVAKINELTKDLN--GMQVP-VKIIV--KCRTEFEIEVGTPPTCALLLKEAGVEK------GCGD-KK-NFVGDICMDQVIKVAEIKRKNLLCCNLKCAVCEIVGTCGTLGIKIDGLTCKEVQKALACGKAGMTHVIMIDDRPRCLTEGMEICVPVTVVEVPPMCVAALRV-YEPYNGG--IRPAGEGCQVAVCNIFNVGEWIDVCAVTKGKGTQGPVKRWGIMLQK-RKHCRTGKLRH-VGNLGP-WHPARICWRVPQLGQTGYHQRTEFNGFVGYGVVRNEYMLIKGCVPGPVKRLVRMRRAIRG-GIHPREAAQHHAFCQGPGLGPCLRTVATAARVLALKLNVPLVGVNHCIAHIEIGKWKT-----GARDP-AVLYVCGGNCQVLALRR-GRYRI-FGETLDICVGNMLDKFARCVGLPHP----GGPRIEELAR------NA--KEYIPLPYTVKG-----MDFCFCGLATETAFAMLVEVTERAGGVGANRRLGEMLRLM-CEERGARFYLPERRFMGDNGCMIAYTGLVMLKCGRIRLCGTNPATLDEICNQVRGIAQRTGVHMAGPIPLPTKRLVVPCRKCPDGEGCATWDHWEMRVHKRLIDL-DADERALRQLMRIQV---PKNVNIEIIRFGLICPQEFRKMCVVKVITADTYDDDGF-PIEMGLMDPRL-GVIDPGLRCRTCGGRPGEC---PGHFGHIDLVAPVIHVGFAK----LIRKILRAICRECPY-------CRDRFERICD--EDR----PEWTILTVLPVPPVTMRPCITLECGQRCEDDLTHKLVDIIRINQRFQENREAGAPQLIIEDLWELLQYHVTTFLDNTVCGV------PPARHR-SGRPLKTLCQRLKGKEGRFRGCLCGKRVNFCARTVICPYPNLCINEVGVPIEVAKELTVPIMVTPKNIEVVRKYVMRGPDNHP-------GVNYVDRQLADGDIVLFNRQPCLHRMCIMAHRVKVMPYKTFRLNPAVCPYNADFDGDEMNLHVPQTEEARAEAEILMRV-QENILCPRFGGPII--GGIHDYVTGCFLLTGKQIFCLILPDGYRAGELEPLPGRTLEETLEMRINCGVVMAVCGARGCMLNLTQMAACVGQQCVR--------GERIKRGRTLPHFKRGDL-GAEAHGFVECCYKKGLCPTEFFFHAIGGREGLVDTAIRTCQCGYLQRRLVNALQDMGT--VAAKIRVMPECTDIDMECLR-PIAFGLKALIAVVLLDDKAGGGTEEVEEAFCKVKGVVKGPKGELCRELWYP-DIEIKREDCK----ITIAAHIKNMIRGVTDGFEYRMRVVYCHFPIQVKVADGK--VAICNFLGERKPRFATIV-G-DVNVEV---GK-DE-ILIRGMDKEAVGQTMANIGVDEAGKGPVIGCMFVAGVDCKLLCPTRRECMERKIDRKHIVVAAACIIAKVARDRCIRDLEA---ALGGRARRPLIIVE---NGGKIEYLDAEEGICTALVPYPEHNACPRNTMGAGMIKQGFPMAN-IRLRPDTRGHYLHY-PQQPVCTRTAKAIG--FDKRPA--------GQNFVVAYEGYNIEDALVMNKCAVERGLARCHFFRVCEAEERKYPGGD-KFEIP--DLEVR--GARGCETYGQLDA-DGLVNPNADVRFL--EEPTEFG-IC--PQQRRETCRCNEKGVVDLVLAKVKTRDQRGDKFACRHGQKGVVGLLLPQEDMPFCENPHAIPCRMGHVLEMIGG-------KGKEVLYDGATGERIQADIFVGVILYQKLYHMVTGKMHARCRGPVQVLTRQPTEGRAREGGLRFGEMERDVLIAHGAALALKERLVEECDKVTELVCCK--CGYAFKLLLDEIKCLGVAPRLDAGLFVEALNGFPGVYGELRGVIGFEARGTG-GFGYDPIF-EV-------DG---RTLAEMDLEEKKTAIARATFKEGKGRIRINEIIEP-ALARMKMMEPDVDVCVMGGGVMGQADAVRTALARLKEAYAEYDRNLLVCDHRQKEKKK--FGGLGARAKYQKCYRT-SPPCQEPLYGERVWDPRRCKLLYLGAANGTTVCYLGDIL-TGGMIYAVEICPRVAQRNQAEIACRNGLMV--VMIKA-----RCIDCTARCTEIFDE-EIRRLVFYNPRMKTN--RDDICPCACRRIRENDLDPFGCPAQFLAPAACC-ARC--YLFITATDTAPLCGAHLKCGVRKYLAVPL-NTEYHREMGVRILMGAVIREMARVDRRGI--PLLCYATEHYVRVHMRIKKGAREADEALE-SMGLYGPPGVGKTCAALALALREICRCE-------GIECEPEAVMHIAAMCGGDLRCAINDLDLCVKGYINLKPRIVLHTGGRHAKQQFKKCELHVVERLINKMMGQKQIAYRIVEEAFDIIHCRTKENPLCVLVRAICNAGPREEVVRLKYGGITVPKAVDTAPQRRVDTALMLIAKGAWQAC-FKCRRCIQNCLADEIIAAANYD-VK-SFAVCRKDCIERVAKAARRG-HRTY-HGKHKNQRGGGCRGGRGNAGT---CKHHWV-RCIIRGEP------MG--KHGFKVLGKGKVTRRLTVAAAAFCCCARCKIEAAGGGYRVCELA------KMRLEEIAELLPCRQRRTLRR----GAKTHLRDAIVLPEMVGKVVEIHNGKTFQRVEIIPEMIGHYLGEYALTRARVIHGAAGVGATRCCKFVPLKADNTGARTLFVVCVKK-Y-RGVKNRQPCAGIGDMVVVCVKKGTPE---MRKQIFNAVIIRQKKEFRRPDGLRVKFEDNAAVITDDA-GV-PKGCEIKGPVAREVAER-FGKIACCARLAACELGVGECRVWINPDPEVACELADAITREDIRAHIEAGNIKAKPKKGNCRARFRLRAEKRA-YGHRKGPGRRRGAKGARA-PPKEIWICRIRALRRHLREMRDCEK-IERHAYRLLYRKAKGGEYRCIAHLWIPKTRLGRLVYEGQVTTFEEAVRCGLPIKEHQIIDLLL-PGLGRRVKFRTTVIVGNRDGYIGIGHGKDVQVGGAIKKGIENAKLNVVRINRGCGCWECGCGQAHTVPYKVCGCCGCVRIYLMPAPRGLGLAAGDVAKKVMEMAGIKDVWTRTEG-----STRTTLNFAKATYNALEYLAKELDRAGYGGMVMNRT-PMGTQITVYAEKPGMVIGKGGKLIRKLTRDLERRFR-LDNPQIDVQDV---GKCDLNARVVANRLACCLEHGWY-FRKAGQCMLRRVMDC-GALGCEIVICGKLTG-PRCRVEKFLAGYIKHCGKPAEEIVDTGYAVAVKKLGAIGCQVRIVPP--GAVLPDLRAILTPEARERLCCIRMTRPEFVAQIEAQLIMLAQCGRIRCAITDEQLKAILHCGTLDPRVTGILPVLTGDATRVVEFLLTAGKEYFCGEIYQRPPLKCCVRNLRTRKIYYIDV--LGTYIRKLCYDMGLALGCGANMEELRRTKAGPFAEDETL-VTLPVERALRHLPGLVICDNAVDAICHGAPLAAPGVVIYTLKGEAVPAVERPAGHVHFKRKL-GWTVGILLLYFVLCNIPLFGG--SLMLLGIGPIVTACIVLQLLVGA--EIIKLNLRD-PRDQAIFQGTQKQVCL-GGVLILYMDEVVCKG-----IGCGVGLFIVAGVTVGIILLVVLVECTRIEIPPVKLVYACVLPMIFAIF--WIETTGMGA-KCIAAKIHACGLQIPGYRRCPVCIERLMERYIPKVTVIGGAIIGLLTVIACLL---GTLGGA-----GGTGLLLAVCIMYRLYEQIACEQIQEMYPLIKEMALEIGT---VVLCCGRTCYVDLRRIVLTPD--LCGLIVRKKAKGKRRF--IEG-PLM-EAGAKVAVVDDVVTTGNCLLRCIERLEEAGGINAARKMEDDWKKLRWCDPHYCRRAL-GLKVKADPLGGA------PRARGIVLEKVGVEAKQPNCAIRKVRIQLIKNGRQVTAFCPGDGAIGFIDEHDEVVVERIGGRMG-RCMGDIPGVRFKVVA--VNNVCLEEMVCGR----KEKPVRLIPIDEYL-----AAGVHIGTQQK--TCDMMK--YIYRVRT-DGLYVLDVQATDKRIRLAGKFLANY--EPCKILVVCARQYGQRPATMFAKAVGARANVGRFIPNTLTNPHFAGYIE--------PDVLLVTDPAGDGQAVKEAVDIGIPVVALCDTNNMTCNVDLVIPTNNKGRKALTLIYWLLAR-QV---LRERKQCIVVREDLRLCTGKLAVQVAHAWMQEGMRKIVLRGRDEEHLFQLRCEAECLGIPAAIVRDAGLTEIPPGTVTALGLGPAPDDIMDRVTGRLCLRYIVVTGGVMCGLGKGITAACIGRLLMNKGYRVTAIKIDPYINIDAGLMCPFQHGEVYVLKD--------G-----GEVDLDLGNYERFLDIELTRDHNITTGKVYCTVIEKERRGEYLGKTVQIIPHITDEIKRRIEICLIEVGGTVGDIECMPFLEAMRQLKYEEC-GNIFFVHVTLAPMTCD-GEQKTKPTQHCVKEMRELGLQPDMIVVRCKKPLLPETKAKIAHFCDVPIEAVICGHDCDDIYRVPLQLEAEGMKDAYLCIREALKHDGILVPGGFGARGTEGKMNAIRYAREKGIPYLGICFGMQLAVIEFARNVCGLEGACCTEFG-ETPHPVQEKV----RQMGATMRLGNYPAHLIEGTLAHRIY-GTTEIVERHRHRYEVNPA-YIEVLEKNG-----LLFC----G---RNGDLMEIMEI--PG--HPFFFACQFHPEMRCRPGRPCPPFRGFKECVDLAINLHNIDLTQ-PGNRVDTEVILPHGRG-RPNRIAVFAAGDTALKAKAAGADYVICPEELKLLGENRKNARKLADEYDFFIAETQFMPVIGKTL-GPILGKRGKMPVRIRCRDRPTFHIAVGRRDMDARQLAENIECVITKLEQTLKDGRR--NLKCVYVKTTMGMGYPGKC-HKTYDR--PRKPWEADRMANEVELIKTYGLR---NKRELWKAECILRKY-RR--VGRMLLCRFGIL---KDGADLDAILCLKITDILERRLQTQVYRQGLANTIRQARQFITHGHIQVAGQRVTVPCYLVKRGDEMTIIKCPYVPEKVTNMIDKDNTIEFIVDLRATKPQIKKELEDLYDVEVVDIRTKKAVVRLAGDK--TANELATRLGIIDICGNPVGEIVL-PAIFDEEYRPDLIKRAVLAAQANRLQPYGPHFYAGMNTCA------RCWGP--GHGVCRVP-R--IVTGR-----R-AAAVPMARGGRACHPPVPCKVLCEKINEKERIKAIRCAVAATAKPDIVAARGHLFCG--EL--PIVVRGEIEC-ICKTCELRRFLMAAGLWDDVMRAKNGR-KVRAGKGKIRGRRFRQPRCILIVNLPGVDFVTADRLNAELLAPGTHAGRLTVWCEPCARLKCHGAVFEVLVDPDGALAMR--RGE-D-VRIEDILAVEDVFENACRGDRCAEEDLLKAFGTTDPLAIAEIIIKKGEICLTAEQRRRVIECKKRQVIELIARNAINPQ-TRTPHPPCRIEQAMAEAKVHIDPTKCLEELVAITMKAIRPIIPIRFEEVEVAVKVPACYAAKCYGEICTFG--KLVREAWQNDGCWIGVI-RIPAGMQTEFYCLVNRLTKGVRPIRCGTVIDHIQAGQA--------LNVLKILGICG-TTGAT--VCVLMNVCCRKLG-K-KDIVKVEDRELREDEVNKIALIAPGATINIVRDYAVVEKYAVDLPDVIVGV--VRCQNPCCICNTN--EPIKPKMLVK-GKN-PVVLRCFYCTNPRLVRLICDLKAACRECKAAIWRDVAERLEKPRRNYA--AVNLCKINRHTGDD-----DTVLVAGKVLGAGEIDHR-VTVAALGFCEQAACKIICAGGRC--MKIEELIR--LHPKGTGIKIPVRCFCCGKVICCVWEEYRERI---KCE---PP-----GKVMDDLGIERYCCRRMLLCHLKEGRYIII------DDEPCIIKCIAHCKPGKHGAAKARIDAIGIFDNQKRCIVAPVTTKVYAPIVERKTGQVQLMDLKDYTTGKEVAYLCC-MGKVKMKYIIYADITADGIVDV-----VGAFGQTEGLLGCDL----DLRDLQKTGRLGRIA---AALETIDR--------VGPCMARIHVTKIEDVRAAKRKYIIDRAVLDCDAILVVEGRAD------VLNLLK--YGIKNAVAGTN--IPPTITELCCKKIA--TAFTDGD--------RGGEL------IVKELLQV-ADID---YVARAPEGK-CVEELTQKE----IIRALDIAAEK--GLDYLIGAKMG-SI-AKTPNLEPRIGKVVVHIGVGEC---GQRLVNAETILCEIT-GQTPIRCRAKKTLPAFGIKKREPIGTRVTLRGRAAEEFL-ETAFK--VA---GGV-IKKCQFDENGNFAFGIEEHTDFPGMKYDPEIGIFGRIAITRPPEITAVRP-VAKVDLDCYILIAGPPGCGKCTLAAGIAEYLLKC-NY-VVKTMECPRDLQVPP---EVTQYGPLEG------SMEACCEIL--------LLVRPDYTIYDEVRKTQDFVVFADMRLAGV-GMIGVVHANKPIDALQRLLGRVELGMIPQV---VDTVVFIERGEVTKLLDVEFVVKVPTGMVE--ADLAR-------PV-VVVKDF--ETGAVEY-EGKCARKPTGG-RLVPARG-KRKYELGREPAETLVG--PI--RVKKIRTRGGNQKLRLLKADVACVCDPVTGATKLVKIETVVDNPANRHYVRRNIITRGAVIRTEIGEARVLCRPGQDGVVNAVLAGRILADVLGKACAKIDVGVCLLGVADYVENTIR-EMGGEPA------FP--CNICRDREAAHYTPKPNDDAVFGE-EMVKLDIGVHVDGYIADAAVTLVDACRAALDAAIELVGPGVCTCEIGRAIECAIEGFGFKPVCNLTGHGLCRFNAHTEPT-VPNGDVIAIEPFAT--NGCGRICDAPLVEILWEVEGAIVCQAEHTVIVTECGCEIITCQ-PRKCA-RECEYFCPITENLCVG--CGICVRKCPFGAITITNLPEEIGA--PVHRYGCNGFALYGLPI-PVEGKVTGILGPNGIGKCTAVAILCGLLRPNKPQ-----YIDR---IPKCY--RGC-VRELLKRTNER---G-ELDALVDRLGLCHLLDREIDCLCGGELQRVAIAATAARDADFYFFDEICPYLDINQRILAARMLQDLAC-----NKAVMVVEHDLALLDLLAECVHLAYGTP--GAYGVITRPKGIRVGINQYLRG----FLPEENVRIRFELCAMPGV-IRRCEVVGILGPNGIGKCTYIKILGG--IEKPTN------GY-------KPQYL-KAE---SDVTVEALLLCGGELQRVAIIACLCMDADLYLLDEPCAHLDVEQRMMAARVMRRFAECTERCVVVVDH--------D
Methanosarcina_barkeri_str._fusaro                      GAE-VAITGCNPLCT-----QDAKYGVECQEYYKAIDQVLD-----IKPDITIDDGADLIFKLHGGCEETTTGVHRLHAMEKEGALKMPVIAVNDAMTKYLFDNRYGTGQCAWDGINRTTNLLVAGKNVVVAGYGW-CGRGVAMRACGLGAN-VIVTEPVRALEARMDGYRVM-KMADAEIFVTTTGNRDILTAENFKCMPDGAILANCGHFNVEIDMGALECL-AKCVRTVRHN-IKE--------YDLGD--RRINVIAEGRLVNLAA--GDGHPAEVMDMCFANQVHKVPLELDTFVARMKLQCMGITIDELTTTQECYMCGWDIGGLGAEIMRVREMIE-LPMKHPELFGHLNIEPPKGVILYGPPGTGKTLIAKAVANEC-----GACFHYIAGPEIVGKFYGECEERLRKIFEEATQDAP------SVIFIDEIDCIAPKRENVTGEVERRVVAQLLTLLDGMVERG------QVVVIGATNRVDAIDPALRRPGRFDREIHIGVPDTKDRYEILGADLLALVQEAAMRCLRGPPGTGKTLIAKA---VAKECNANFICVKGP--EIFCKWLDEIDCIACMPGMECTDCHTCERVLNQLLTEMDG--LECLRDVVVIAATNRPNLLDPAILRPGRFDRAVAHIKCCFNNTIITVTDITGAETIAKCCGGMVVKAARDECCPYTAMQMAGQLADQLRDKGIHGIHIRVRAPGGN-KQRCPGPGAQAAIRAFARAGIRIGRIEDVTPVPHDGTRPK---GGRRRCAGRFGARYGRKDRKLVADLEERMRAPHVCTKCAR-PTVKRIGTGIWKCCKCGHTFAGGTYIPVDKGAIRFVCNGADIMAPGIVGADPEIKEGDLVGKAIKCICHVGDYTYVRDAWKNPDE-TYVNELRWERMQVWRKQGCVTRIERPTRIDKARCLGYKAKQGIVVARVKVRRGGLGKTRPNRGRRTQKMGTCKITG-GMRIQRIAEARADRKYPNLEVLNCYWVGEDGKNKWFEVILVDPFHPVIKCDKNLKWVCDPCVRDRAARGKTCAGQKGRGMVINLEHDPARCAPIAKVVFE---TGEERLLLACEGIAVGCTIGDDADVRPGNIVPIGKVPEGFFICNIECKPNDGGRFVRCCGVYAMPCGNIKWLNPKCRAVVGIVAGGGRVDRPWLKAGKKYHKMKTRAAKYPRVCGVAMNPVDHPFGGGAWKH-PG--KPTTVCR-NAPPGRKVGLIAARRNIGIVAHIDHGKTTLCDNLLAGAGMICK--ELAGRQLFMDCDEEEQERGITIDCCNVCMVHNFDNED----YLINLIDTPGHVDFGGDVTRAMRAVDGAVVVVDAVEGTMPQTETVLRQALREHVRPVLFVNKVDRLINELKVDCQEMQIRLGKVIDHVNKLILDMVIHFLPDPIEAQKDRVKVIWHGDENCEIGTCMTHANADGDLAFMVTDICVDPHAG-EVATGRLFCGCFCRGMEVFTCGT-AKKCRVQQVCIFMGPERLEVDKIPAGNIAAVTGLKEAIVGCTECIRHVCEPVVTVAVEAKHTKDLPKLIEVLRQVAKEDPTLQITLDEETGEHLMAGMGELHLEVIAH-RIERDKNVEITTCKPIVVYRETIKKKI-EPVEGK------SPNRHNRFYIYVEPGIQYLNETMELILDGFEEVMRAGPLTREPVANVKCVLVDAKLHEDAIHRGPAQVIPACRQAIQAGMLMADDTLLEPYQKVFVQVPQLLMGGATKELQGRRGIILNMCTEGDL-AIIEARVPVAEMFG-FAGEIRCATEGRAMWCTEFGGFDIVPDPLANALCTIKNAEAIGKCCCIIRPACKNIGNVLKVMQDLGYIGEFEFID-DGI-YCVTLVGR---VNKCG-------AIKPRYCVGTGCFER---WEK-QFLP--AKNFGALIITTCCGVMCQYEAREKKIGGQLLAYVYGDGTVTLVGFPCVGKCTLLNKITPGLV-KGACCGRGRGREVIC-VIRNCDLD-------EYKIHNALKDCIYDRLGFIRVYLKPQGQCADMEEPFRY-----AQVGIDHRMQD----EDMTTVFDVPAMELIEKVAGILKEN-ENVVPPEWAKNVKTGVHKELPPNND-D-WWYIRTAAILRKIYTDG-PVGIERLRCIYGGKKD--NG--SQPYHKAKGCGCIARKAVQQLEAAGYLQKVKD---GRTVCAKGRCMLDNAADANGLILGRLACTVAGDEEIYIVNAEKAVICGCRATTLKEYR-ETRERGC----TEFGPYFPKRPDRILKRTIRGMLPY-KRARGGKANPGPPLGPALGPLGVNIKEVVEKINEKTRDYN--GMQVP-VKVIV--DDKKNVEIEVGTPPTACLIMKELGIQK------GCGNAGC-EVVGNICICQVAKIARMKKEDVLCYDLKATMKEVMGTCVPMGVTVEGVEARDCQKALDQGKVGMTHVIMVDDTKNCLTQGMEICVPVTIIETPAIRVAAIRA-YAEDTAG--EKAIAEGTLVCITDVFKTGTLIDTAAITIGKGTQGPAKRWGIQLMK-GKHCRQGCLRQ-IGTLGG-FGLRRVCWRVPQMGQTGYHQRTEFNGFINYGLVRGDYVLIKGCVPGPCKRLIRLRDPIRG-GIHPREAAQHHAFCQGPGLGPCLRTVATAARMLCICLGIPLIGVNHCIAHIEIGIWRT-----PAMDP-VVLYVCGANCQVICYMG-GRYRV-FGETLDIGLGNALDKFARGANLPHP----GGPKIEAYAK------NA--TKYIHLPYVIKG-----MDLCFCGLCTETAFAMVVEVAERAGGVGANTRLREMLNDM-CEARGAKFYVPEKRFMGDNGTMIAYTGLLMYKCGRIRLCGICPKDLDGVCNQVKCIAERTGVNICGPVPLPTKKLVVPTRKCPCGDGTATWDHWEMRVHKRLIDI-AADERALRQLMRIQV---PKDINIEIIKFGLLCPKEIRKMCCTPIITADTYDDDGF-PIDMGLMDTRL-GVIDPGLRCKTCCGRAGEC---PGHFGHIELVAPVVHVGFNK----VIRKLLRATCRKCPY-------CRDRFENIPD--DDR----PEWMILTVLPVPPVTVRPCITLECGQRCEDDLTHKLVDIIRINQRFQENREAGAPQLIIEDLWELLQYHVTTFFDNCVCGI------PPARHR-SGRPLKTLCQRLKGKEGRFRGCLCGKRVNFCARTVICPDPNLCINEVGVPMPIARILTMPCVVTPRNIEQLKIYVRNGEDIHP-------GANYVERQLKDGDIVLFNRQPCLHKMCIMAHCVKVLPNKTFRLNPAVCPYNADFDGDEMNMHALQTEECRAEAKILMQV-QENILCPRFGGPII--GGIHDHICGLFLLTGKQIFCQILPDGYQNKELEPLPGRTLDETIEMCINCAVIMARCGARGCILNLTQMAACVGQQAVR--------GERIRRGRTLPHFQKGDL-GCDAHGFVKACYKCGLNPTEYFFHAIGGREGLVDTAVRTCQCGYLQRRLVNALQDMGD--VAAKIKIMPECVDTDLGELEEPIAFGLKALIVTLIVNDEE-GGTEPAEEAFAKVCGVATGPLGTVERKLWYP-GIKIYVRDGE----VTFTCHIKNLMKGVNEGFECKMTILYAHFPMQVKVDGKT--LIIGNFLGEKKPRIAKIL-G-ETKVKV---SG-NE-VTVCGINKEDVGQTAANIGIDEAGKGPVIGPMCIGGVDCKKLTPKKREQLAAQIDATYPVVCAACIIAKVRRDELIEELKK---EWGGRARRPLIVVE---NGGCIEYLDAEEGICTGMVPYPEHNACPRNTMGAAMIKQGVATAN-QKLRPDTRAHVLHY-PQRATRTRTCEAIG--FDDRPA--------GQNFVVAYEGYNIEDALIFNKGCIERGLGRCHFLRTFEGEERRYPGGD-KFEIP--DCEYR--GARCAEAYANLDT-DGLVNPETPVRFL--EEPCDFG-IC--VEQRRECCRCNETGIVDTVLAKVKVRDERGDKFACRHGQKGVIGLKVPIADMPFTENPHAIPCRMGHVLEMIGG-------KGKEVFYDGATGKMIPADVFVGVILYQKLHHMVTCKMHARCRGPVQVLTRQPTEGRAREGGLRFGEMERDVLVGHGAAMCLKERLLDECDKVVELVCCH--CGYAFKLLLDEIKCLGVAPRLDCGIFIKVLNGFPGPYGVVEGEIAYEERGTG-GFGYDPIF-EY-------QG---ITFGELGDVEKKNATARATVTKGTGKVRINELYTP-ELVMMKICEPDINVDVRGGGIIGQANAVRTAVARIRDNFACYDRNLLVCDCRQKECKN--FGGPGARAKYQKCYRTKNLDPGKTVYGERTWDPRRCKLLYLGAACGTTVCHVCDIV-SEGAVYAVEFAPRVAQPNQAEIAARNGYLL--LCIKA-----RCIDTVAKPKEVFKA-EVKKLVFYNPEMELN--RDDWCPEAFELIKENDIDPFGTPAPFLDAACAC---VRGMLCVTATDTAPLCGAHLKAGIRKYACVPL-NTEYHCEMGLRVLLGACARELAKHEKGML--PLLCHVTRHYVRTYLEVLPGTKQTDRTLK-SMGLHGPAGVGKTCTAHALALKKVCECE-------DILCCPDAIQQIAEGAGGDLRCAINDLDLGIKRYVCLTPVIVPHCCGKHARQQFNKCEICIVERLANNLMGKKQKTLRAVEEAFDIVCKKTKQNPIQVLVDAIANAGPREEVVRLKYGGICVPKAVDTAPQRRVDTALRYICMGTNNAA-FKCKRCVAECLATELIGAANRD-TK-SFAINRKDAKERVAKAARRG-SRTCGGGTHKNRRGAGNRGGRGKAGA---CKHHFV-RAMFRGYC------YG--KHGFKVLGCGRVMKNLVVTCEGFCACAREKIEAAGGGKTVCELQ------ELCLEEFAELLPCRERRCIKR----GVRTHHRDLIILPEMIGQTIEIHNGKGFVCVDLQPEMIGHRFGEFAPTRCRVCHGCAGVGATRCCKFVPLKVDNTGAKVVEIICVKK-Y-RGVKNRMPCAGIGDMCVVCVKKGTPE---MRKQVLLAVVVRQKQEFRRPDGLRVCFEDNAMVITDEE-GI-PKGTDIKGPIAREVAER-YPKIGTTARLACKILECGLDRVWL--NPEACEEIACAITREDIRGLIENGTIKAKPIKGVCRGRARALAAKRK-YGHCKGQGCRKGKKGART-PKKEQWIKKIRALRRRLKELRADGT-LDKCVYCRLYRKAKGGEYRCVAHLWIPKTRLGKLVMEGQVACMEEAIKCGLPIREPQIIDMLL-PDLGRRVKFRATVIVGNRNGYVGLGQAKDVQVGPAIRKAIDAAKLDITYIHRGCGCWECACGLPHTVPYEVTGKAGCVCVTLIPAPRGLGIAAGNTATKVLEKAGIKDVWTKTFG-----TTRCTLNFAKATFDALEYFAEQLNRAGYGGMELNRT-PMGTQIVIYCEKPGMVIGKAGKVIRKLTRDVAARYN-LENPQIDAQEV---KKPELNAQMMACRLAACIERGWY-FRKAGHNTLRAVMNA-GALGCEVVICGKLTG-ARCRVEKFVDGYIKHCGNPVDEVVDEGFAVAIKKLGTLGCKVRIIQP--GVVLPDLRQILTPEARERLTTLKMCRPAIGEQLEMQLICLAQCGRLPCQICDEQLKTLLHAGCLDPKVTGLLPTLLGKATKAVPALRLCGKEYFTGPIYQMPPIKCAVRVIRIRTIYYLEV--LGTYIRKLCHDIGLALGCGGHMQELRRTKAGPFTEETL--VTLPMETAVCHLPKIILRDCAVDAICCGAALAVPGIALFTLKGELVPAVACPEKHVHFKDKL-WWTLGVLLLYFALANVPLFGG--SLILLGIGPIVTACIVLQLLVGA--DIIKLDLCD-PKDQCFFQGAQKQIFI-GGALILFMDEVVCKG-----IGCGVGLFIVAGITIVIFLLVVYVECTRIEIPPVKLIYACVLPMIFALF--WIETTGMGA-KPTAQKIFNCGMQIPGFRRNICCIEKVTQRYIPKVTVIGGAFIGLLTLIACLL---GTLGCT-----SGTGLLLAVCIVYRLYEDIACEQMMEMHPLKACGAVRYGN---FTLACGKKCYIDIKKACTDPP--L--LIVRKCVKGTRCR--FVG-DFK--PEDRIVMLEDVTTCGGCVRNAIEVVRETGGKYAANILKQTRKNARWKDTCYGRRVL-GLNVKADPLGGA------PQGRGIVLEKVGVEAKQPNCAIRKVRIQLIKNGRQVTAFCPGDGAVNFIDEHDEVTVERIGGRMG-GAMGDIPGVRFRVTA--VNNVCLNQMVIGR----LEKPRRLVCIDEYL-----AAGVHIGTQQK--TQDMMR--FVYRVRT-DGLYVLDIQCTDERIRVAAKLLCHY--DPCRILVVCCRQYGQHPARMFCRALCTKCMLGRFIPGLLTNPQIHGFFE--------PDIVIVTDPAGDAQVLKEACCIGVPIVALCDTNNLTCNVDLVIPTNNKGRKALCLVYWLLAR-EV---SRLNKQCIVTREDLKLCKGKFAVQVAHAWKEGGQKKIVLKVPTLNDLYELKEKARREGLPTALIQDAGLTEIPPGTVTVLGIGPAKEELIDKVTRNLKLKYIIVTGGVMCGLGKGITIACIGRNLKDKGYKVTAIKIDPYINIDAGTMCPYQHGEVFVLKD--------G-----GEVDLDLGNYERFLDTELTRDHNLTTGKIYLEVICKERRGDYLGKTVQIIPHVTNEIKCRIDICLIEIGGTVGDIECMPFLEAVRQMHREEPCENIAFIHVTLAM-EDLQGEQKTKPCQHCVKELRALGLCPEVIVVRCKCPLQECAKEKIALFCDVPQELVICAHDADDIYEVPLEIEEQGLEDCYLCILEAVKHDGILIPGGFGGRGTEGKMMAIKFARENDIPFLGICLGMQLAVIEFARNVAKLKGANCTEFDEDCPYPVQTGV----AEMGGTMRLGDYEAILTEGCIAAKIY-GTNYIVERHRHRYEVNPE-FVDRLECYG-----IVFC----G---KNKNRMEIAEI--PG--KRFFFGCQFHPEFRCRPGRPCPPFRNFCECVDLAINLKNLDMNL-PKNRVDEEVILPHGLG-KELKIGVFAKGDVGLRAKAAGAAYVICDVELDELACDKTRARTLANECDLFIAETQFMPTIGKNL-GIVLGPRGKMPIRLRCKDKLTFHVPVGRRTMCPDDLAENVEIIVCRLERVLDKGRH--NLRTVYVTTTMGMAYPGKK-SKCFET--PRHPWQEARMACEVQLVKAYGLR---NKREVWKAACTLRMY-RC--EARRLLIRYGII---KCDADIDDILCLKTENILERRLQTQVLRLGLARTVVQARQFITHGHIAINGRKATVPGMLVCKEDEMHIINYPFVTEKAMMLLD-ENKLQFIVDTRCNKKQIVEDVEKLYGFKVKCVRTKKAILTFEDPE--SAHEIATRIGTIDLTGKVVREIEL-PDVFDVDYRPDLIKKAVLAAQANRLQPYGPRLYAGMETCA------RGWGC--GRGTCHVP-R--LVNCC-----R-AARVPHARGGRRAHPPKPEADRCEKVNTKERRYAIRCAIAATRDPTLVCLRGHIFEA--EL--PIVTENALED-LDKTKQVIEFLQAIGVYEDVLRAKYGR-HIRAGRGKLRGRKYKHKKCVLIVNLCGVDVATVDCLNAELLAPGTHAGRLTIWTECAARLKRGCKHFEVLVEPEGALAYK--RGE-D-VNLEDILAVETIFEDANRGDRAAECDILNCFETTDPFKIAAVILKCGELQLTAEQRKRMLEEKKKKVIYTICRNAINPQ-TKAPHPPARIEKAMEEAKVHIDPLKCVDQLVNITMKAIRPLIPIRFEEVNIAVKIPPEYAPKAYGDICKIG--SITKEEWQRDGCWIAVV-RIPAGVQTDLYALINHLTKGIQAIENGTVIDHIKAGQA--------LNVLRILGICC-AFRAT--ICFVMNAPGAA-G-I-KDVVKIEGKELCVEELNRIALICPKATINIIRDFKVVQKNKVVLPCYVEGV--VRCINPNCICN-SC-EPIKCKFCVLQCEEEGVTLNCLYCTNPRIVCLILTLKERANTNTAPIWKDIARRLEMPCRNYA--AVNLCKINRHTAED-----DVLLIPGKVLGAGLLDHP-VTVAALTFCDCAVDKITEAGGKC--LCLEEIME--ANPKGCGIRIPVRCFCCGKVICNYWDEYKRRV--SDGE---NA-----AAVLDDLGITRYCCRRMLLCHLKEGKYVII------DDEACVIKCITKCKPGKHGAAKARVEAIGLFDGQKRCYIGCVANKIYVPIVERKTAQVQLMDMGDFCTGEEVCYITA-LGKIKLKYIIHCKINADGVIDI-----VGAFGQTEGLLGADL----DLRDLQKTGRIGRIA---ACLETIDR--------VGPCCAKIEVFQVEDVRAVKRKKIIERAVLNCDAIIILEGRAD------ILNLLR--YGIKNTICGTN--IPPEVAELTKKKTV--TAFTDGD--------RGGEL------IIRELLQV-ADID---YVARAPDGK-CVEDLVQKE----VIRALDIACCN--AIKNLIGVKIG-NI-AKVPMRTPVVEKVIVHMGVGEC---GQHLVDAEEILRNIT-GQEVVRCFAKRTLPAFCIKKNEPIGCKVTLRGQRAQQFL-ETALG--IV---DKT-LVRCQFDCLGNVCFGIEEHTDFPGMKYDPNIGVFGRIAIAHPPEITVVRP-TVVVDLEHYILIAGPPGAGKCTFAAGVARYLNDH-GQ-VVKTMECPRDLQVPP---EITQYCPLNG------RMENTADLL--------LLVRPDYTIYDEVRKTCDFLIFADMRLAGV-GMIGVVHATRAVDAIQRLIGRVELGVIPQV---VDTVIFIDKGEVAKVLVLEFTVKVPHGMTE--QDLAR-------PV-IVIADF--ETRRVEY-EGCCRRKVTGG-KVINARG-KRKFEMGRECAETRIC--EI--KRKNVHTMGGNRKVRLLQCDVANITNPKDGKTTCAPIETVLDNIANKHYIRRNILTKGCVIRTPLGTAKVTCRPGQDGVVNAVLAGRILKTVRAEAVEMVRVGNTLLQVAEFVENRTI-ELGGRPA------FP--CNICRNQEAAHATPKIGDTDVFGK-DMVKLDLGVHVDGYVADCAVTIKKAAEEALAAAIDLAKPGICTGELGAAIENCIRCYGLNPILNLTGHGLCQYEAHDDPC-VPNGDVLAIEPFAT--DGVGAVHDGNWAEILLECAGGLVAQAEHTIIVTQDGCEITTCQ-PRQCC-KECEKYCPICEELCVG--CGICVHKCPFKAIMIIGLPETLTE--PTHRYGVNGFALFGLPV-PRVGKVTGILGPNGIGKCTCVQILCGTLIPNKPQ-----YVDL---IPKAF--KGK-TCELLENTDER---G-VLDELIDYLDLNCIVDRKICELCGGELQRVAIAACAAKDAQFYFFDEICPYLDIYQRINVARLIQEICK-----DRTVLVVEHDLALLDMLADVIHIAYGEP--AGFGVVTLPKCVRVGINQYLKG----YLPEENIRIRFCLKAAGGC-LREGEVLGVVGPNGIGKCTFVKVLAG--EIKPDE------GY-------KPQYI-KAD---IPVRVQDFLLCGGELQRVAIAACLCQEADLYILDEPCAHLDVEQRCMVTKVLNRFAENNNKTALVVDH--------D
'Methanospirillum hungatei JF-1'                        GAT-VHITGCNPLCT-----QDAKRGCCVDEYYQAIDTVLD-----AKPVITIDDGMDLIHRLHGGCEETTTGIHRLRAMAADGKLLFPVIAVNDTPMKHYFDNVHGTGECALTAIMATTNCLIAGKWIVVAGFGF-CGRGLARKACALGAK-VIVTEPRRALEAHMEGFHVM-SMQEADIFITTTGNRDVITGDHMTVMKCGVILCNAGHFNIEIDGIWLCCH--ADTIEERDG-IHC--------YHIG--GKVIHLLAEGRLVNLAVPKGMGHPIEVMDLCFALQVHQVPDEIDRMVACYKLACLNLCIDKLTKDQEEYMGCWDFIGQDCIKDALTVAIT-SARKR--------NKPLDHILFCGPPGLGKTTLAHIIAQEM-----NCHIETTCGPVLDRP--GDLAALLTP-LKDRD-----------FLFIDEIHRLCPVIEEILYPAMEDYTIDLL-IGEGPCARTIQLPLERFTLIGATTRLGLLGCPFR--------------DRFGIILRLGIPITP---EGAAEIAGGTPRIANRLLKRA---------YDYAIVRGT--GCIDQNIDQ-------KGLDILDRRILEVIANDFDGGPVG--LKTICICVGEEPRTIEDVYEPYLIRIGFLKRGVAHIYACFNNTIITVTDLTGAETITKCCGGMVVKQDRNECCPYAAMQMAGNVAQAAREKGIVGLHVKVRAPGRG-KQRCPGPGAQAAIRALARAGMRIGLIEDVTPVPHDCIRPKGGRRGRRGCTGRFGPRYGRFIRKRVRDVELICKATHTCPRCDT-VCVKRKGTGIWECRKCCFKFAGGAYVPVDMGAVCYVVNGADIMRPGVVDVTPDVTAGKPVGKVARTWHHVGDYAYVRDAWKIPDD-TGVKALLWERMQDWRREGCIVRVRRPTRIDRARALGYKAKQGIVVVRVKVRRGGRRACRYVRGRRTARMGVNRKTM-GKCIQRIAEERACRKYPNMEVLNCYWVGEDGRQKWYEVILLDPHHPCIINDKTLNWICKPGHRGRCERGLTCAGVKGRGMIIDIEHDPARHTPIALVDVP---DGENTYVLVTEGMGIGDVLGADAEIRNGNTLPLQEIPTGCCVCNIEAYPNDGGKFVRACGVQAMPCGCTKWFNGQCRATIGIVAGGGRCEKPFVKAGKKYHKMKNTACNWPRVRGFAMNVIDHPFGGGGHQH-AG--RPKTVCR-GTCPGRKVGHIAARRNIGIVAHIDHGKTTLCDNLLAGAGIICE--DLAGKACWMDCDEEEQARGITIDACNVCMVHEYNGKE----YLINMIDTPGHVDFGGDVTRAMRAVDGAVVLVDAVEGTMPQTETVLRQALKERVKPVLFINKVDRLINELQVDEMEMQIRLGKVIDKVNKLILDMVVCFLPNPKEAQPRRIGVIWHGDVNCPEGKGMITCDPNAPCCLMVTDICFDPHAG-EVATGRLFCGKLCRGNEMYVMGTAKKVNRLQQVGIFMGPTRVEVPELYAGNIAAVTGLKDAIVGCTECLEHYCEPVVTVAVEAKNMKDLPKLVDVLRQVAKEDPTLRVNINEETGEHLICGMGELHLEIITG-RIKRDKGVEIITCEPIVVYRETITQELTEPVEGK------SPNRHNRFYFTLHPGIQYLNETMELIIEGIHEALDGGPLADEPVQNMLIKLVDVKLHEDAIHRGPAQVIPAVRCAIKGGMLLAGDCLLEPMQKLHITVPQDHMGCATCQIQCRRGQVFDMTCEGDT-ITVIGKAPVAELFG-FAGDVRCATEGRAMWNCEFAGFEIVPNTVADAMCTLKNACDTGRAECIVQPAGRLIGELLRIMKEAGYIKEYTRIE-DGQ-FKVVMCGL---INKCG-------CICPRYCVCLDEMEY---WEQ-LYLP--SKNIGMLMICTCKGVMGHHDARRNGVGGELLGYVYGDATVVLVGFPCTGKCTLLNVLTPGLI-AGAAMGKGRGKEVIA-VVRNADLT-------ENRIACALKDAIYNALGFIRIFLKPQAGPADMDEPFRY-----ARVGIAHNLAD----EDMTTVYDVPADKLIAKAAMELKEK-AEITAPEWAPFVKTGTHREMPPEDP-E-WWYTRAAAVLRRVYVDG-PVGVERMRCVYGGKKD--RG--SKPCKCVKGCGCILRKCLQQLEAAGFVAKQKN---GRVITPAGACFLDGIADGDGLLLGRLACNVAGEE-IAVVNAEKAVICGNRARVLGNYK-QKRQRGC----REGGPFFPRRPDHILKRTIRGMIPY-KRERGGKATAGPPLGPALGPLGINVKAVVDEINKKTACFN--GMQVP-VRVEV--DEKKNFTICVGIPPTTALIMKEAGVEK------GCGEPNT-KIVGDVPLEAAVTIAKMKLDDMLCYDLKNAVKEVVGTCVCLGITVCGKKPKDMLKEIDCGKVGMTHVIMVDDHAHCPNEGKDIMVPVTVIEVPDMRVAAIRV-YRHDTYG--NHVLTEGKDFDIRCLFKVGQYTDVTAITKGKGTQGPVKRWGVHLRK-RKHCRGKKERH-VGTLGP-WTPHHVRWQVPMMGQMGYHQRTEFNGFINYGEVRARYVLIKGCVPGPCKRLVRIRHAMRG-GIHPREAAQHHAFCQGPGLGPCLRIVGTAARALALCFDVPLIGVNHCVAHVEIGRFAC-----GFDDP-VVLYACGANTQVLGYLQ-GRYRI-FGETLDIGIGNAIDKFARCKGLPHP----GGPEIERIAK------NG---SYIPLPYTVKG-----MDLAFCGLVCETAFAMCTEVTERAGGVGMNKRLQEMLCCM-CEDRDAAFCVPNPQYLGDNGAMIAYTGRVMLECGRIRLTGTDYQKVEEVCEKIKEIAERTGVNLAGPIPLPTRKLVVPIRKCPDGEGTATWDRWQMRVHKRLIDL-DADERALRQLMRTQV---PKDIGIEIIEFGLLCPKEIRQMCVRKIIWADTYDDDGF-PYPQGLMDLHL-GVIDPGLRCKTCCQKAGEC---PGHFGHIELAKPVIHVGYTR----LIRKLLRVTCRECPH-------CRARLEKIPD--DDR----PEWTIMTVLPVPPVTMRPCIILENGQRCEDDLTHKLVDIIRINQRFKENQDAGAPQLIIEDLWELLQYHVTTYIDNEVAGC------PPARHR-SGRPLKTLCQRLKGKDGRFRGCLCGKRVNFCCRTVICPDPNLCVNEVGIPQKIANEMTIPVQVTVFNIDELRRIVRVGPDRPNL--KCPCGANYVERHLRDGDIVLFNRQPCLHRMCIMAHWVRLMDGKTFRLNPAVCPYNADFDGDEMNLHIPQTEEARVEAAMLAAV-QENILCPRFGGPII--GGIHDHICGIFLLTNKQIFCKILPDGFEDGQLEPMPGRTPEETLEMQINCAVVMAVCGARGCMLNLTQMAGCVGQQAVR--------GERIMRGRTLPHFKKHDR-GAMAHGFVMNCYKCGLNPTEFFFHAIGGREGLVDTAVRTCQCGYLQRRMINALQDMGD--VALIIKVMPECPEVNRETIE-PIGFGLVAIKVALVVPDAE-GQTETIEATLNAIDGVVKGPKGNLQRDMWYP-GIEITIGCED----VTLACHCCNMCTGVTKGYLYCMKVVYCHFPIQIKVVGET--LEIVNFLGEKYPRCARIL-P-GTTVKV---GC-DE-VTVTGIDKEVVGCTAANIGVDEAGKGCVLGPMVVAAVDCKKLCCKCREKICADIDCLFPPVCAACIIAKVERDRIIEELCK---EYGGRARRPLIVLE---NGGYIELIDAEEGIGAAHVPFPEHNACPRVTMGAGMVKQGFGCAN-MKLRPDTRGHLLHY-VQKPVYTQTCDVIG--SDDRAA--------GQNFVVAYEGYNIEDALIFNKACIDRGVGRCHFFRTYEGEERRYPGGD-RIEVP--DEDVT--GAHGCDYYANLDD-DGIINPETIVRFL--EEPTCEL-IT--VEKRRDTCRCNEHGIVDTVLVKVRTRDLRGDKFACRHGQKGVVGLITPCVDMPFTANPHAIPCRMGHMLEMLGG-------KGREAMWDGITGRRFLADIYVGVIYYQKLYHMVCCKMHARCRGPVQVLTRQPTEGRAREGGLRFGEMERDVMIGHGAAMALKERLLEECDKVTEYVCAR--CGYAFKLLLDEMKCMTIAPRLDTGLFIHALNGFPGTCGAIKGTIV-LPRGCG-GFGYDPVF-EV-------DG---KTLAEMTEEEKKTAVARATFRPGKGVVRINDVFCT-ELARMKICEPDVCIKVAGGGIMGQAEAARTALARMKDVYHVYDRCLLVNDCRQKEAKK--PHGRGARKKFQKCYRPGAVLPGDRVY--RIWDPGHCKVLYLGAAAGCTVCFLCDYA---EVVYAVEFCPRIAQRDQAEIALRNGHLI--LFLKL-----LCMGTDKKREDRIVE-VVNLLVFYNCRMALN--RDDRDQLAIDLITHNDLDPFGTPAPFIDAAIRC-SGK--YLGVTATDTAPLCGAHLKAGIRRYMARPL-NTEYHTEVGLRILLGNVARHAAVYDKGIT--PLFCYAHEHFVRLHLQLKCCACAADKCIA-RLGLYGKPGIGKTCCAWALALREICCRE-------QLTCCAQALTDIAEQCGGDIRCAVTMLDPGIARYVNLNCMMVPHCCGRLTRQEFHKANMLIVERLINQLMGKKQLAIRIVRDAFEIVHQKTKKNPIEVLCDAVANAGPREETVRLKYGGINVPKCVDTAPMRRVNTAVGLIAAGVYCAC-HKKKKPVANALAEELIAAANGD-VK-CYCVAKREERERVAKCARRG-SRTCGGGTHKNRRGAGNRGGRGRGGC---RDHKFV-RGVVHANW-----TYG--TCGFKVLGGGQVTCKMNITAEAFCQCAIQKIEAKGGGYKIDELR------AMCLEDLLPVMPCRARRKVLR----GIRTHQRDMIILPEMIGREIEIYNGKEFIRVELQPECVFHYLGEFALTRRRVTHGCAGIGATRCCKFVPLKADNTGARVVQVVCVFG-Y-HGVRRRQPKLGLADIATVCVKKGTPD---MRRKLVRAVVIRQKKEIRRPCGLRLCFEDNAVVVVDDK-NE-PRGTEIKGPVAREVAIR-YPRIGCMARLAADVLGCGVNRVWF--NPEKLTEIQQAICREDIRNLIQDGAIAAHQKRGNCRGRARAQMAKRC-YGHCKGPGRRKGAAGCRT-NCKDRWIQRIRAQRRVLRELRETGD-IDRCVYRKFYRRAAGGQFRTVCHMWVPLTGLGRMVQAGEIKCIDEILCCGKPIKEPEIVDAFL-PDLGRRVKFRAVVVVGNRDGYIGFGQGKDAQVGDAIKKAIVCAKINLVKVRRGCGCWECGCCNPHCIPMLVTGDAGCVRVTLRPAPQGIGLVTGDIGKKVLELAGIRDVWAQTQG-----QTRTTINYAKATFNALRHLGHELKRAGYGGMDLIRT-PLGTQVTIFAEKPGIVIGKGGKVVRTLTQDLATTYG-VECPQIEVQQV---DNPNLNAQIMAERLACALERGWY-FRKAGCCTLRRIMDC-GALGCEVVICGKLTG-ARGRVQKFTEGYIKHCGDPVNTLVDKGYAVAIKKLGVIGVQVRLIPP--GAQLPDLMQILEPEARERLNTIKLTKPDFARAVEQQLVMLAQCGRIKNKICDDQLKVILHTGTLDPPVCGVLVILLGRAVRLTTILHQDDKEYFTGRIYQRPPKRCAVRALRIREIHELEM--LGTYIRCLCHHIGMACGVGGAMVELRRTRCGPFCEKDC--VTLCPLEALHGFPRIQMKECAADAICHGARLCCRGVVMLA-GDDFIPAVKTPEGHVHFKNKL-AWTAAILILYFALTNIPVFGG--SIVHLGIGPIVTACIVLQLLKGA--DLIHIDTCE-IRGQIQYMGLQKQICI-GGVLIFLMDEVVTKG-----IGCGVGLFIIAGITIAIFILIVYVECTRVEIPPVKLIYACVLPMIFALF--WVKTAGLDC-KAVARQIQLCGMCIPGYRRNPAVLEKVLDRYIPRVTVIGGVFIGIMCVVANLF---GVIGAV-----SGTGLLLTVCITYRLYEQIACEQIMEMYPLICAEAIRFGD---FTLACGKKCYIDIKKAITCPP--Y--VIIRKEQKGLACL--IIG-DVA---GKRILLVEDVTTCGGCAVFGIEQLRCAGGKFAARKLKRDCARFRWCDPHFARTAG-GLKLKCDPLEGA------PQGRGIVLEKIGVEAKQPNCAIRKVRVQLIKNGRQVCAFAVGDGAINFIDEHDEVEIEGIGGRLG-RCMGDIPGVRFVVTK--VNNVCLHELVIGR----KEKPRRLVCVEEYL-----AAGVHIGTQQK--SCDMKN--FIYRVRG-DGLYILDIRETDERIKLAAKFLCQY--DPAKILVVTCRQYGQYPARRFADCIGATPIIGRYIPGTLTNPLLPRYAE--------PDVVVVTDPVCDLQVIREAIQVCIPVVALCDTNNMTCLVDVVVPTNNKGRKALCMIYFLLTK-EF---LRHKKQCIIIRNDVKMCCGKKCAQAGHAWMNEGQKKVVLKAADQKTLFELKTLAECAGIAAVLIQDAGMTEIPPGTITALGLGPAKCEDLDKITGCLCLKYIFVTGGVMCGLGKGITAACIGRLLKNRGYQVTAVKIDPYLNIDAGTMNPAQHGEVFVLHD--------G-----GEVDLDLGNYERFLDIELNCCHNITTGKVYRMVIDKERRGDYLGQTVQIIPHITDQIKDCIDICIVEVGGTVGDIECMPFLEAVRQMRCELATADRALVHVTLMPCDCM-GDLKTKPTQHCIKALRELGIFTDIIVGRCERPLNCHTKKKLCCLCDIPQNGIICAATAPDIYQVPMELEKEG-EDVYLCIKEALRHDGVLIPGGFGVRGIEGKINAIRLCREERIPLLGLCLGFQLCVVEFARNVLGIADACCCECGDGTA--VQEGV----ENLGGTMRLGDCPVEIKCGTIAYKLY-RQHEIIERHRHRYEVDPA-YICRLEDAG-----LIFC----G---RNGNRMEIAEI--ED--HPFFFATQFHPEFRCRPTCPCPPFRKFTECVDMTINLKNIDMCQ-PKNRIDETILLPHGNG-RVVKIAVLGCGDIVTQARECGVELIMGPEEIERLGGAPREARKIACEHQFFLAETQVMCLVGRWL-GPRLGPRGRMPVKIRTKDKMCFCLKVGTTAMCEEEIAENIDAVLKRILCKLEMGDF--QVRCVYIKTTMGMGYPGKN-HKQYQT--PKRPFELCRIEEETRLVIEYGLR---NKREVWIAKGALRKY-RK--AAREILQRCGML---SENADIDDVLALKVEQQLDRRLQTQVYRRGFARCPKQARQFITHGHIAIGGRRVTIPGYTVCAKEQEEILKYPYATEKACMIVERDGQLQFIVDRKACKGQIKVAIEKMFDQPVTRVRTKKAMVCFCNPK--AAEEILCRLGVLTLTGCVAHEIEL-PPVFCCEFRPDLIKKAVIAQQCRRYQPHGAYVYAGITACA------VGWGC--GRGVCHVP-R--LKNCC-----R-AAKVPQAKGGREAHPPKVEKVLIRNINQKEKRKALNCAIAATICPELVRCRGHVFTG--SL--PYVLCGDFEC-LKKTKEVIAALRAVGVYGDVERAERCR-KVRAGRGKLRGRRYKQRKCLLIVNLAGVDVCLVDNLNVELLAPGTHCARLTLWTEDAAKLECHGERFEILVDPDLAAKIR--QGE-D-IPIEDAVAALQIFENACQAERACEECLKKVFKTTEFEPIALHIIRKGEIHLTCEQRKVLTAEKRRQVITFIARNAVNPQ-TGHPHPPQRIELAMEEAKVHIDPFRCVEELVKDTMKALRPLIPIKFDEVRVAVRIPPDYAPRAYGEICAVA--AIEKEEWQKDGCWICVV-VIPAGIQTEFYDLINRICHGICTIENGTVIDHIKAGEA--------LTVLRILGITG-STREC--VCVATNVCCKAQE-K-KDVVKIEKRELKAQEVDRIALVAPNATINIIRNFRVIEKKGVIIPPVLIGV--LRCPNPCCITNTN--EPVMCRFEMH-----GKKAVCCYCCNPRLAELIRLLKQTCRENEVEIWCDIACRLEKCRKNYA--EVNVCKINRYAQEG-----ETLIVPGKVLGCGVVEAG-VTVAALCFCDAAVCKITEAKGQC--ICIEQLLC--QNPKGCRTRIPVRCFTCGKVICTAYEEFKRRR--DACE---DP-----KRILDDLGMDRYCCRRMLLTHLKEGKYLLV------DDEPCKILCICVCKPGKHGAAKARLDVVGIFDGVKRCIVQPVCAKVYAPIVERRNAQVQMMDLECFENGKETMYIYC-MEKRKIKYRIHLVVQADGVVDV-----VGAFGQIEGLLGCEL----ELRELQRQGKLGRIA---ACMETINR--------VGPCVCEIHVQCIEDVRITKRTQIIERAVLACDAIIVVEGRAD------VINLLR--AGIKNAVAGTC--IPKTIIDLCRKKTT--TAFFDGD--------RGGDL------ILRELLEV-TDVD---FVAYPTRGE-SVEDLCRKE----IIKALDQFCMH--GIRYLAAPCFT-GI-VRLPNRCVAVDKVVVHMGVGEA---GDKLVNAERIICEIT-GNTPVRCVAKQTLPAFGIRKGAPICCRVTLRGEAAEKFL-ETCIK--IV---ENK-INCRAFDKQGNFCFGIEEHTDYPGQCYDPKVGIFGRICITRRPEITAVRP-IVDLCLDDYILITGPPGCGKTTLAQAIATYLCDE-GV-IIKTMEQPREMLVPD---QITQYTALDG------SMANTADVL--------LLVRPDFVIFDELRRNEDFEVFADMRLAGI-GMIGIIHAVCPHEALQRFADRLDFCVLAQI---FGCMIYVRDGQIHQICCTAFCMKVPEGIDC--DMQIR-------PV-TTVCDV--KTNLPIF-EGRCVRKCTGG-RYCPCRG-KRRREIGCAPAETHIG--ID--RRKICRTYGGNNKVRALRCEYAAICNAKTGETKKVKIETVEENAANPNYVRRNLLTRGAIIRTELGRARITCRPGQHGVINAVLAGAAAKKILCEGAERIRVGACLLEVAEFVENCIL-DEGFGIA------FP--VNICLNEAAAHDTPCPDDTRTFAKGDMVKLDLGVHLDGYIADTACTLCEACIAARDAAIAAVRPGVAIGTLGTIVAHEIKCRGFLPVANLTGHGLDQYCLHKGPN-VPNGMVLAIEPFAC--TGTGFVHDGRREEILCDVPGCYVCQAEHTMIVTGDACIVTTCH-SRKCG-TECILYCPICEELCVG--CGICVKKCPFEAIDIITLPEELEH--PTHRYGPNCFVLYGLPA-PIEGKVTGVIGANGIGKCTCMKILCGQICPNKPQ-----YIDV---IPKVF--QGK-VWDLLKTTDER---G-ALDQYLDILCLRQILDQEICNLCGGELQRVALAAALARNADFYFLDEVTPYLDIYQRMAAACAIRDLAT-----EKPVVLIEHDIAILDMLADTVHIAYGKP--AVFGIITRPKGVRIGINQYLDG----FLPEENVRFRFCLTVHPGE-IFAGEVIGVVGQNGIGKCTFAKLLAG--VEKPDC------GY-------KPQYL-KGD---SCDTVEFFLLCGGELQRVAIAACLCQPADLYVLDEPCAHLDVEQRVRLTKIFRNQVEGKEAAILVIDH--------D
Methanothermobacter_thermautotrophicus_str._delta_h     GAE-VAMTGCNPLCT-----QDGWRGETNEEYYENIHRVLD-----HEPEILIDDGADMIFLVHGACEETTTGINRLRAMAADGALKFPVMAVNDAYTKYLFDNRYGTGQCTFDCIMGTTNMLIAGKTVVVCGYGW-CGRGIAMRAEGLGAC-VIVTEPIRALEARMDGFRVM-KVCDADILITATGNTDVVCECEFMNMKDGCVMANCGHFNVEINREALEEL-SRETGKVKED-IEV--------FIMPD-GRKIYLLAEGRLVNLACERGQGHPAEIMDMCFAMQVYRAPDEIDLMVARMKLDAMGIEIDELTEKQRLYLENWDIGGLKEEVKKVREMIE-IPLKRPELFERLGITPPKGVLMHGPPGTGKTLLAKAVANEC-----DAHFIAINGPEIMCKYVGGCEERLREFFEEAEENAP------SIIFIDEIDAIAPKREDVCGEVERRIVAQLLTLMDGLKCRG------QVVVIGATNRPDALDPALRRPGRFDREIEIGVPDREERKEILGADLECLCKECAMRVLRGCPGTGKTLLAKA---VANECQANFIAVKGP--ELLCKWVDEIDCIACVRCGCTADCGVTQRVVNQLLTEIDG--LEELQDVAVIAATNRPDILDPALLRPGRFDRGIANIYCCFNNTIITITDITGAETITQWCGGKVVRADRQECCPFAAMEAATRAADDAKEKGIVGLHIKVRAPGGN-GPRTPGPGAQAAIRALARAGMRIGKIEDVTPIPHDGTGRPGGKRGRRGITGRFGPRYGRKAKRAVKKIEEEMKRKHVCPCCDR-PGVKRECRGIWKCRKCGAVFTGGAYLPVDMGAVRFLANGADVMCPGIVDADPEICENDTVGKAVKTIHHIGDYRYVKDAWKNPKD-SYVRELMWERAPKWRRDPVIKRIERPTRIDRARALGYRAKPGYIVVRTRVRRGCQRKTRFKAGRRPTRMGVKKITT-AKCIKRIAEERVARKYPNMEVLNCYWVWEDGKYKFYEVILVDPNHLAIKNDPKIYWICVKQHRGRVFRGLICEG------VVDIMHDPGRTAPVARVKFE---NGEERLILAPEALMLNEEVGVKARVKPGNCLPLCEIPEGTPIYNIENRPGDGGKLVRCCGTYALPCGELKALNPQCRATVGVVAGGGRREKPFLKAGKKYHALRAKGKKCVTVRGVAMNAVDHPHGGGNRQH-PG--RPTTVCR-HAPPGRKVGCIAARRNIGIVAHIDHGKTTLCDNLLAGAGMICA--ELAGDQRFLDFDEQEQARGITIDAANVCMVHCYEGNE----YLINLIDTPGHVDFGGDVTRAMRAVDGAVVVVCAVEGIMPQTETVLRQALKENVRPVLFINKVDRLINELKLDACELQERFVKIIANANKLILGMVVEHLPCPAECQAYRVPIIWCGDLECEEGQAMLKTDPEGPLAVMVTDVCIDKHAG-EVATGRVYGGAIEKGCEVFLVGC-HCKARVQQVGVYMGPERVNTDKVPAGNIVAITGAKNAVAGETEGLEHICEPVVTVAVEAKNTKDLPKLIEVLRQVGKEDPTVRVEINEETGEHLICGMGELHLEIIAY-RI-NEKGVEIETCEPIVVYRETVAGTA-GPVEGK------SPNKHNRFYIEIEPGIQYLDEIKELLMDGFECAMDNGPVAKEKVMGVKIKLMDAKIHEDAVHRGPAQVLPAIRKGIFGAMMCAEPVLLEPIQKVFINVPQDYMGCATREIQNRRGQIVNMTQEGDM-VTVECTVPVAEMFG-FAGDIRCATEGRCLWCTENAGFERLPDPLANALTNIRNNEIRGNVKCRITPACKLIGRVLRTMQKEGYIGEFEYVD-DGK-FIVELEGN---INHCG-------VIKPRHAVKKDEFEK---FEK-RYLP--AKNFGIIIVCTPEGIMTHKEAKDRGIGGRLLAYVYGDCTVVLIGFPCVGKCTLLNELTPGII-TGACRGRGRGREILC-VARCADLN-------EYGIHNALREEIFNRLGLIRIYLKPQGKKADYDEPFRH-----ARVGLEHVLND----EDMTTVYDVPADLLINRVAEELK-NDCKVKCPEWVNFVKTGVHKERRPENP-D-WWYVRAAALLRRVYIDG-PVGVNCLRTHYGGKKD--RG--SRPEKFRRGCGAIIRRALQQLEECGLIKREEN---GRVITPEGRCFLDKAANGEGHILGRLACVVCGEE-VIVLNAEKILITGCKEWAYGKYK-QRIDRACICNPRRMGPKYPRRPDDIFRRTVRGMLPY-KKCKGGKATPGPPLGPAIGPLGINMMQVVEEINRKTADFE--GMKVP-VKIIV-DTDTRDFEVEVGTPPTTALIMDELKLEK------GCQDPGM-DKIADICMEQVLKIARMKFDALLCNDYKRAVKEIMGTCVCMGITVNGKDPREVQREVDQGKAGMTHVMMVDNQKNCPTEGMEVCTPVTILEVPPLTVMAVRT-YEKTCRG--LKTLGEGKDVRACEIFCEGAFVDAIAVTKGKGFQGPVKRWGIRIQY-GKAARCCKGRH-IGCLGP-WTPCRTMWTVPQAGQMGYHRRTEYNGFVRYGLVRNDYVMIKGCVPGPTKRLVVLRKAIRG-GIHPREAAEHHCFCRGPGLGPALRTVATAARTLALCLDVPIVGVNHCIGHIEIGRLTT-----GACDP-VCLYVCGGNTQVIAFNE-GRYRV-FGETLDIAVGNMLDQFARECGLGHP----GGPVIEQLAL------KA--SEYIELPYCVKG-----MDICFCGLLTETAFCMLVEVTERAGGVAVNRRLRDMLREM-CQEHHVEFHMPPPEYCGDNGAMIAWLGQLVYKYRRIKLTGTDPEKLAYVCDQLKKIAERTGVDMCGPIPLPTKRLVVPTRKCPDGEGTATWEKWEMRIHKRLVGI-EADERAMRQVMKVNV---PDNVCIEIINFGLMCPEDIRKMCVTQIVTPDTYDEDGY-PIENGLMDPRL-GVIDPCLRCRTCGAKGGEC---PGHFGCINLARPVIHVGFAD----TIHKILRCTCRKCPH-------CRERLERICD--DDR----PEWMVLTVLPVPPVTVRPCITLETGERCEDDLTHKLVDILRINQRLKENMEAGAPQLIVEDLWELLQYHVTTYFDNEACGV------PPARHR-SGRPLKTLAQRLKGKEGRFRCNLCGKRVNFCARTVICPDPNICINEVGVPEIIAREVTVPVYVTEWNIDRMREYIENGPDVHP-------GANYVERHLKDGDIVLFNRQPCLHRMCMMAHQVRVLPYKTFRLNLCVCPYNADFDGDEMNMHVFQTEECRAEAKTLMRV-QEHILCPRFGGPII--GGIHDHICGAYLLTGKEIFCMVLPDGYENGELEPLPGRCLEETLEMKINHAVIMALTGARGCMLNLTQITACVGQQCVR--------GGRICRGRTLPHFKKGEL-GAKCRGFVHCCYKEGLDPIEFFFHAMGGREGLVDTAIRTAQCGYMQRRLVNALQDMGD--VVATIKVMPECPDVDLEALE-PIAFGLVALNVMVVVGDAE-GGTEAAEECLCGIEGVVKGPKWELCRKFNHC-EICMAVEDDK----VTVRAHICNMITGVTEGFRYRMKIVYAHFPMCVKVAGDK--VVIENFLGERHPRTARFV-G-DTKVQV---KG-DE-VEITGINKEHVGQTMANIGIDEAGRGPVIGPLVVAGVDCKKLTPERRRFLARKIDTRYYPVAAACIIAKVERDLEIECIQKKNRKLGGRARRPLIIVE---DGGIIEYLDAEEGICAGIIPFANHNCCPRNTMEAGMTKQGLYACN-YDLRTDTRAHLLHH-PQVPVKTRIIDVTG--YDERPC--------GQNFVVAYEGYNMEDALILNKACLERGLARCCFFRCYEAAERRYPGGD-RFEIP--EKGVR--GYRCECDYRHLDE-DGIINPEAEVRFL--EEIDEFG-TV--AERRRETCRHGEKGIVDAVLAKIRVREQRGDKFACRHGQKGVVGLIVCQEDMPFTENPHAIPCRMGQVLEMLAG-------KGVECLYNGITGERIEAEIFIGVAYYQKLHHMTTDKVYARCRGPVQVLTRQPTEGRAREGGLRFGEMERDCLIAHGAALALKERLLDECDKYEALVCAD--CGYAFKLLLDELKCLCIFPKLDAGLFIRALKWFPGPYGVVKGRIGTEERGTM-GFAFDPLF-YP-------EGMD-KCFGELCTCEKKTAIARGTIREGKGRVRINELYTP-ELARLKIMEPDINVRVVGGGIVGQAEAARMVIARLKEKFVQYDRTMLVGDPRRCEPKK--YGGRGARARRQKCYRTINPNPGVKVYGERVWDPRRCKLLYLGACAGTTACHICDIV-TDGRVYCIEFCPRVAQPDQTRLFIENGYGL--IMIKA-----RCIDVTRCPRKIFRE-EVGKLVFYNPAMEFN--RDDINPLAVECIKNNDIDPFGTPAPFMDCAAAC-ARNNCLLAVTATDTCCLCGTYIKPCLRKYCCRPL-KTEYCHETGLRILAGFTAMNLARYRKAAC--VLLCHCCQHYMRLYIRVRRGARRADECIR-NIGLVGPPGTGKTTLAHIIGLRRICRAE-------GIECPDDVLRELAKRCRGDLRCAINDLDMGLAKYICLDCILVPHTMGRHVKRQFAKCKVCIVERLINKVMGKKNKAYKIVQEAFEIINRRTKENPVQILVKAVENTCPREETTRIKYGGIGYQVAVDICPQRRVDLCLGFITRGAMQAA-FKNKKCIEECLANEIMLAAEYD-TR-SFAIQKKEEKERIARCAHRG-SRTVGGGCCKKRRGAGHRGGRGQAGG---HKHHWT-WIVKYDPK-----HFG--KYGFKVLGCGRITRPVHLKAYEFCRCATEKIEEAGGGYTLEELQ------EMPLDDVIKLFPCRQRRCLKR----GIRTHCRDMIVLPEMVGMTFGIHNGKEFVEVKIQPEMIGCYFGEFAPTRKKVEHGDPGMGATRFCMFVPLKVDNTGAREVEIICVRG-Y-KGVRRRLAAAGVGDMVVVCVKKGTVD---MRREVLNAVIVRQKKEYRRPDGLRVKFEDNAAVIVCPE-GV-LKGCEIRGPVAKEAADR-WPCVGCAARLAADILKVGVNRIWI--DPERIDEVCRAITRDGVKQLIKDGAIKAKPKKGICCYRCKKIAQQKK-KGRRRGPGCIKGAKGARR-PKKDEWMTTIRALRKDLKEMRDNRE-INKCTYRKLYKMAKGGAFKCKCYMWEPRTQLGRLVKEGVITCIDEIFEEGHPIMELEIIDALL-PDLGRKVNFRVIVAVGNKDGYVGLGQGKAREVGPAIRKAVDDAKFNIIKVRRGCGDWGCVCGREHTVPFKVCGKCGCVRVTLIPAPGGVGLAIGDVGKTIMRLAGIDDVWCHTRG-----QTQTTVNFARATFDALEYLEKELERAGYGGMDVQVT-PMGTMVVVYAERPGMVIGRGGKTVRAITQKLKNKFD-LENPQVEVKEV---DVPELNPKIMAHKIAAMLQRGMH-FRRVAYTTMRRIMAA-GAQGVEVTICGKIRG-ARCATAKFTDGYIKKCGEPCVKHVREGFATVQLKPGVLGVYVRIMPP--DVVLPDMMQILTPEARCRLANLRLTRPDFVEQIELQLIQLAQMGRVRCKITDEQLKELLHGGTLDPKVTGVLPLGIDRATRVMQLLLEAPKEYFQGKIFQIPPLKCAVRDLRVRTIYRVDI--LGTYVRKYCHDVGEALGAGAHMAELRRTAVGPFTEEGL--VTLPMEFAVGHLPRVVILDCAVDAICHGADLARGGVAIMTLKGELVPQVKCPGYRVPFREKL-KWTGIILVLYFFLAQIPLYGG--SILTLGIGPIVCACIILQLLVGG--KILKLDLCR-HEDKAFFQGLQKQLTI-GGILIIFLDEVVCKG-----FGCGVGLFIAAGVLIAVFLVVVYAECMRVEIPPLRFIYACNMPVIFAWL--WVEICNIGP-RHVARQLYQMGMQIPGFRCCRGQFEKILKRYIPTITILGGAFVGLLAFVADLT---GCLG-------GGTGVLLTVGIVYRLYEEIAQEQLMDMHPLCEMDVVQRGK---FILCCGRECYVDIKRAVTEPP--L--LMIRKEKKGTCKL--IEG-DLQ--KGDRVAVVEDVTTTGGCLLKAVRAIQENGGLFAAKKLKCKRQKFKWKDTHYKRRCL-RLDVKADPLEGA------PQARGIVIEKVGIEAKQPNCAIRKVRVQLIKNGKQITAFAPGDGAIGFIDEHDEVVVEGIGGPCG-RCMGDIPGVRWKVTK--VNNVCLQEMVKGK----IEKPVRLIPLDKYL-----AAGLHIGTQQK--TADMEK--YIYRVRC-DGLYVLDIRKTNDRVIAACKFLCKY--EPDDILAVCTRQYGQEPVRKFGEVTGARTIPGRFIPGTLTNPNYAKFIE--------PEVLVATDPRCDCQAIIEAKQIGIPVVALCDTENLLGNVDIAIPVNNKGRKAIALVYWLLAR-QF---LREKKQVIIVRCDLKMGKGKIAAQACHAWELEGCKKVIVCVNCLDELLEIYRAVKEAGICNYLVRDAGHTQIPAGTITCLGIGPDDDEKIDKITGDLKLKYIVVTGGVVCCIGKGITAACIGRILRCYGLCVTAIKIDPYLNWDCGTLNPYQHGEVFVTDD--------G-----METDLDLGHYERFLDCDLPGEANITTGKVYMCVINKERCGDYLGCCVQIIPHITDEIKCMIEVVLVEVGGTVGDIEGQPFLEALRQLRNEEGHENVMFVHVTYVPYLRAAGEFKTKPTQHCTKELRCTGINPDMIICRCEMPIDCCLKRKIAHFCDVEEEAVVNAPDACCIYEVPLVLDCERLEDCYICIREALKHDCILIPGGFGERGIAGKLEAVRFALENRVPIFGICLGMQCMVIEFARLN-GMEGANCTEFDPETPYPVQKRI----KNMGGTMRLGCYQCRIREGTLAHEAY-GTELVGERHRHRFELNNE-FREELECKG-----LIIC----GTC-PDDFLVEMVEI--KD--HPWFLGCQFHPEFRCRPNRAHPLFRNFTQCMDVILNIKDLDVNK-PENRFDEEVCLPNGRG-KDVKIAVIADGELALQAKNAGADLVITKDELEELGKNRKEAKKLANQYEFFVAQADMMPLVGRFM-GPVLGPRKKMPVKVRIKDQPVVHTVVGTEDMDDEKLAENIEAVLQTIDRKLEKGRN--QLKCMYVKTTMGMGHPRKA-RKKYDT--PPHPWNAERIKEENRLVAKYGLK---NKKEVWKAETMVRRY-RR--DARYLLVRTGIL---NEGAKLEDVLDLTVEDVLRRRLQTLVHKRGLARTVKEARQMVIHGHIALDGRKIDAPGYIVKRGEEDKIIMKPHVTEKCMNLIDQNNELAFVVMRKCTKKDVRRAFEELFAVKVERVNTKIAYIKLAKEH--SAEDIAVKLGVYCLEGEAIDEMEL-PEIFNEEFRPDVIKRAVLCAQTARVQPWGPDPMAGKRTCA------QCYGA--GRGVAMVP-R--IKNGC-----R-AAFVPQAVGGRRAHPPRPQKNYHERINRKERRLAIRCAVAATARKDLVEARGHRIENVPQL--PLVVDDELCM-IKRTADTREVFRKLGIMDDIVRAREGK-KIRAGKGKMRGRKYRTPRGPLIVNHPGVDVVRVENLNAELLAPGTHPGRLTVFTRCAARLECHGERFEVLVDPDLAAEFR--REDCD-VCVEDVLAVQEVFRDARKGDKACEEAMRKVFETADPLEVTPVILRRGTIQLTAEQRRQMIEDKRLKIINKIAREAINPQ-NGLPHPPKRIEKAMEEARVHVDPFKTVDEQVNIVLKAIRTKIPIKFEKVRVAIKIPGERAGCAYGVICNFG--KITNEEWQNDGCWIAVV-EIPGGLQDCFYQKLCELTGGVKPIKNGTVIDHITANRC--------LNVLNILGLP----DGRCKVTVAMNMDCCQLG-S-KDIVKIENRELKPCEVDQIALIAPRATINIVRDYKIVEKAKVRLMDEVRGI--LRCPNPNCITNCD--EGVENRFYVI-SEE-PVLLRCYYCTNPNLIKLIRNLRKKCCQEGAAIWKDVARRLERPTRNRA--AVNICKINRHCDED-----ETVLVPGKVLGCGNLDHR-VQVVALCFCQTARDKIERAGGEC--LTLGKIVE--ENPAIKNIKIPVRCLCCGKPVCAYFNEYQRRV--ADGE---DP-----KDVLDDLGLKRYCCRRMLICHLKVGKYVII------DGEACKITNICTCCPGKHGCAKARVEAVGIFDNQKRCFVKPVDCKVDIPIIDKRTAQVQLMDLETYETGVEVEYIEA-LGQRKLKYLIHAQINANGIVDV-----VGAFGQTEGLLCNDL----DLREFQKTGRIGRIA---ACLETINR--------VGPCEAYIQVTKVEDVRAVKRKRVVERAVETCDAILVVEGRCD------VLNLLK--YGIKNAIAGVC--VPKTVADLTRKKTV--TAFVDGD--------RGGEL------ILKELLQV-GEID---YVTRAPKGK-EVEDLEKDE----IMMALDLCFEK--GLRYLVAVRCG-DI-VKKPMEEVRIFKVTLNIGVGEG---GEKLARAERLLEEMC-GQKPVRTHCKVTNPEFGIRKKQPIACKVTLRGERAEKVL-KMFLE--GI---GNR-LKACQFDEYGNVCMGIDEHIDIPGMKYDPEIGIFGRICIARPPEITAVRP-VARVCLEDYVLIAGCPGAGKCTFAQAVAEFYCRD-MKAVVKTMECPRDLQVGD---EITQYAPIER------DMQKTADIL--------LLVRPDYTIYDELRKTRDFRIFADMRLAGV-GMVGVVHATRPIDAIQRILGRVELGVIPCV---VDTTIFIEDGEVKAVYDVCLTVKVPTGMQE--ADLAR-------PV-IEIRDL--ECGELMH-EGKCMKKPCGG-RAKMNRG-KRKYELGREPAETKIG--DR--RVRLIRTRGGNTKVRLACDTRINVVDPETGKVEIAEIRNVVENTANPHFVRRNIITRGAVVETNLGNVRVTCRPGQDGVINGVLAGKIVCKVRREAAGIIRDGLPIIELVNYVEDRII-EEGGRPA------FP--CNVCVNEVTAHYTCPPGDDCVIGDGDLVKLDLGAHVDGFIADTAITMMDAAREALENAICTIRAGVEVGEIGRVIEETIHCHGMNPVCNLTGHCMERWILHCGLC-IPNGDVLAIEPFAT--DGVGLVTDMPQTYILREKCGAMVAQWEHTVIVEEDGCTVITCQ-PKKCN-YVCIEYCPICEELCCG--CGICTKRCPFKAICVINLPEALEN--PVHRYGQNQFELFGIPA-VTCGDVVGLIGPNGIGKCTIVRILCGELRPNKPQ-----MVDR---IPRYV--KGK-VEDLLTGIDC----D-RTDEVIETLEIREIMGREICNLCGGELQCVAIAAAALREADFYYFDEPTCWLDVRQRLNAVKVIRCLAE-A---GKCVMVIEHDMAALDAMCDYVHILYGKP--GAYGVVCNRRGVRVGINTYIRG----FLREENVRFRFKLDVDEGT-IYLNEVITAFGPNGIGKTTFAKILAG--VEKPDE------GY-------KPQYL-SCD---YTGTVEEFLLCGGELQRLAVAVALCREADLYVLDEPTAFLDVEQRLMAAKAIRRIIEGCNCCAMIIDH--------D
Mycobacterium_tuberculosis                              GAE-VRWACCNIFCT-----QDAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLGVTEETTTGVLRLYQFAAAGDLAFPAINVNDCVTKCKFDNKYGTRHCLIDGINRGTDALIGGKKVLICGYGD-VGKGCAEAMKGQGAR-VCVTEPINALQAMMEGFDVV-TVEEADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERC-GATRVNVKPQ-VDL--------WTFGDTGRCIIVLCEGRLLNLGN--ATGHPCFVMCNCFANQVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDEFIGQPRVREQLQLVIE-GAKNR--------GGTPDHILLCGPPGLGKTCLAMIIAAEL-----GCCLRVTCGPALERA--GDLAAMLCNLVEH------------DVLFIDEIHRIARPAEEMLYLAMEDFRVDVVV-GKGPGATCIPLEVAPFTLVGATTRCGALTGPLR--------------DRFGFTAHMGIELGA---DAGAEIARGTPRIANRLLRRV---------RDFAEVRAD--GVITRDVDE-------LGLDRLDRAVLCALTRCFGGGPVG--VCTLAVAVGEEAATVEEVCEPFLVRAGMVARGAAHIKCTFNNTIVTITDPQG-NVIAWACCGHVGFKGCRKCTPFAAQLAAENAARKAQDHGVRKVDVFVKG---------PGCGRETAIRCLQAAGLEVGAICDVTPQPHNGVRPP---KRRR????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????VAHIEYDPNRTARIALLHYL---DGEKRYIIAPNGLCQGDVVGANADIKPGNNLPLRNIPAGTLIHAVELRPGGGAKLARCAGCCIMPCGEIRRVDVRCRATVGEVGNAEQANINWGKAGRM--RWKGKR---PCVRGVVMNPVDHPHGGGEGKT-SGGRHP------VCPWGKPEG--RTRRNFGIMAHIDAGKTTTTERILYYTGINYKIGEVHDGAATMDWMEQEQERGITITCAATTTFW----KD----NQLNIIDTPGHVDFTVEVERNLRVLDGAVAVFDGKEGVEPQCEQVWRQADKYDVPRICFVNKMDKIGADFYFCVRTMGERLGANAVPIQLPVLDAVVDYLPCPLD-----VPPAIGHAPAKEDEEVVRKATTDEPFAALAFKIATHPFFG-KLTYIRVYCGTVECGCQVINATK-GKKERLGKLFQMHCNKENPVDRACAGHIYAVIGLKDTTTGDTECMTF-PDPVIEVAIEPKTKCDQEKLCLCIQKLAEEDPTFKVHLDCETGQTVIGGMGELHLDILVD-RMRREFKVEANVGKPQVAYKETIKRLV-QNVEYTHKKQTGGCGQFAKVIINLEPGGRIPREYIPCVDAGAQDAMQYGVLAGYPLVNLKVTLLDGAYHEV--DCCEMAFKIAGCQVLKKAAALAQPVILEPIMAVEVTTPEDYMGDVIGDLNCRRGQIQAMEERAGA-RVVRAHVPLCEMFG-YVGDLRCKTQGRANYCMVFDCYCEVPDPIADFLTRLRNANCAYHDEVCL-PHCKLKANIAQILKNEGYICDFRTED--GKCLVIQLKYG---PCRER-------SIAGLRRVCKPGLRV---YAKCTNLPRVLGGLGVAIICTCCGLLTDRQAARQGVGGEVLAYVWAGRICACLGLPERVLTQRLRTLCDCLGWLRDFLRLHTGGLVV--ICHNVDVA-------RIKFPTPLCGGEKTRLALAGLVACTANVLLL-DEPPGA-----AAATEDYWCDE---YRD???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DATDVVLGRLAVAAAGDF-VIVINADKVAICGDKLQHKMVYR-HCGYPGGLHK-RTIGELMQRHPDRVVEKAILGMLP--KNRLCGQANPAPPVGPALGQHGVNIMEFCKAYNAATENQR--GNVIP-VEITV--YEDRCFTFTLKTPPAAKLLLKAAGVAK------GCAEPHK-TKVAKVTWDQVREIAETKKTDLNANDVDAAAKIIAGTARCMGITVE--------------KLGMTQVFDECNR----------VVPVTVVKAGPNVVTRIRT-PERDGYCAVQLAYGEGQELTA-EIFADGCYVDVTGTCKGKGFAGTMKRHGFRGQG-ACHGAQAVHRR-PGCIGGCATPARVFKGTRMAGRMGNDRVTVLN------DAENGVLLIKGAVPGRTGGLVMVRCAIKG-GVVPEIACRAHAATIGPGLAGALLVGVAAAKAYCAAWGVPFYAVNHLGGHLAADVYEH-----GPLPECVALLVCGGHTHLLHVRCLGEPIIELGCTVDDAAGEAYDKVARLLGLGYP----GGKALDDLAR------TGD-RDAIVFPRGMCGPADDRYAFCFCGLKTEAVADVLTMKAVRAGGVAANCRLRELATQR-CGEAGRTLRIPCPRLCTDNGAMIAAFAAQLVAAGRIRLKAYDHEAIDACARKIVETVVRTGACVVGPVPLPTEKNVYCVIRCPHK-YKDCREHFEMRTHKRLIDIIDPTPKTVDALMRIDL---PACVDVNILRIGLATAEDIRQWCYGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPCRLGYLLDLAPKDLDR-------YRNGKGQKKL--RAC----PMGMVLDAVPVIPPELRPMVQLDGGRFATCDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQECVDALFDNGRRGR------PVTGP--GNRPLKCLCDLLKGKQGRFRQNLLGKRVDYCGRCVIVVGPQLKLHQCGLPKLMALELFKPFV--------MKRLVDLNHAQ-------------VLEEVIAEHPVLLNRAPTLHRLGIQAFEPMLVEGKAIQLHPLVCAFNADFDGDQMAVHLPLCAEAQAEARILMLC-SNNILCPACGRPLA--MPRLDMVTGLYYLTGRVMFNELLPDGFQRGALN-------HDERNEALNPIITIVDCGATGNFTQTRTLAGMKGLVTNPK-------GEFIPRP-------------------VKCCFREGLTVLEYFINTHGARKGLADTALRTADCGYLTRRLVDVCQD??????????????????????????????????????????????????????????????VKGPKGTLGLTVAEP-IKVARNDDGA----ILCRTLVCNLVTGVTQGYTTKMEIFGVGY--RVQLKGCN----LEFALGYCHPVVIEA--PEGITFAV---QAPTK-FTVCGIDKQKVGQIAANIGVDEVGRGACAGPLVVAACDCKKLCEQAREKLFPLIDAAAACIAAACVLAKVCRDRVMVALDADHPGYGGRFVEPRVLVRRKAGEAMIPFLEHDDAIDAGDVVVAEECGVIEEVCADYITVMNGTRRT-YRMRKFARCNHGTCANQCPVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAWEGHNYEDAIILCNRLVEEDVLTCIHIEEHEIDARDTKLGEITRDIP----------NICDEVLADLDE-RGIVRIGAEVRLL----RAIFG-EK--AREVRDTCPHGECGKVIGILVRVYVAQKRGDKLAGRHGNKGVIGKILPVEDMPFLANTHGVPRRMGQILETHLGWCAHCGWKGKAMLFDGRCGEPFPYPVTVGYMYIMKLHHLVDDKIHARCTGPYCMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKCDDT---------VGECFKVLLKELQCLCLNVEVDCGLEVAALGGMPGVLGEWPGTIAREPRGDG-GFGYDPVF-VP-------YGDD-RTAAQLCPAEKKEAVVRVRLVPGTGKFDLNEDYFPNKVHQQLIKAPDIFAHLGGGGPCGQAGALRLGIARDRPALKKAG--FLTRDPRATERKK--YGLKKARKAPQYCKRTMCLTPGAEFHTHLVLRPLLVDYLEAGAGCGALTLCLLRAVGPAGQVICYEQRADMLAPWE---VLDAGVLM--VYVATVTQLCRIVEALRAKQCWTEPRAWETLAFLDCTLVGD---D---SDAAELPRIAEIGTLG--------------------GFCTIWLARGAGPQGRVVTLEY--QPK-HAEVARVNLQRA--GVADRVEVVVGPALD--TLPTLAGGPFDLVFIDADKEN---------NVAFCGPRGCGKTCCARILALARICEQE-------GVVVDDAVYPLVIRAGGGCPRDTLCVLGPAPKRPLVNDPVY----------------GCQLVTQLVNKVLGKKCLAERIVYGALEQARDKTGTDPVITLKRALDNVKPALEVRCRRVGGATYQVPVEVRPDRCTTLALRWLIGYCR----QRREKTMIERLANEILDACNGL----GACVKRREDTHKMAEANR?????????????????????????????????????????????????????????????????????????????????????????????------------------------MP----RCLKK----GIKTWCRRCTIIPDFIGHTFAVHDGRKHVPVFVTECMVGHKLGEFAPTRTFKGHIKDDRKCKRR-------ADNTGAKEILCIRVLG----GCCRRY--AGIGDVIVATVKDAIPGGNVKRGDVVKAVVVRTVKERRRPDGCYIKFDENAAVIIKPD-ND-PRGTRIFGPVGRELREKRFMKIICLA???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????GTTDNRDARGDREGRRRDC----GRGCRERDGEKCNYL-----GRRFCFTALVIVGDGNGMVGVGYGKAKEVPAAIAKGVEEARKCFFRVPLIGG----------TITHPVQGEAAAGVVLLRPACPGTGVIAGGAARAVLECAGVHDILAKCLG------SDNAINVVHATVAALRLLCCGLERAGIADVEIERT-RDRVRVDIHTARPGIVIGRRGTEADRIRADLEKLTG--KQVQLNILEV---KNPECQAQLVAQGVAEQLCNRVA-FRRAMRKAIQCAMRQPNVKGIRVQCCGRLGGAEMCRCEFYREGRVPLHTLRAD--IDYGLYEAKTTFGRIGVKVWIYKG--DIVGGK?????????????????????????????????????????????????????HAGTLDPMATGVLVIGIERATKILGLLTAAPKCYLRGEIRQVPCCVCAILEARPIRIDRFEL--LGTYIRALARDLGDALGVGGHVTALRRTRVGRFELDQA--RCL----CLLMFARRDLTAAEACAAANGRCLPAVGYAACDADGRVICAFICCLRTVDLRRKI-LFTLGIVILYRVGAALPCPGLKLTVFAVGVMPYITACIIVQLLTVVIPRFEELRKEG-QAGQCKMTQYTRLVMTGGAALVMWMGELITEG-----IGNGMCLLIFVGIALIIIVGVVFVEQGQRRIPPLKVNQAGVIPVIFTYF--YVCIT-FNP-DERADEMKKFGGFIPGIRPG-RPTADYLRYVLCRITLPGCIYLGVIAVLPNLFLQIGAGGTVQNLPFGGTAVLIMIGVGLDTVKQIECQLMQRNYEVRRLCVVH-GR---VTLCCGREAYVDLRRATLHHPIDA--FVVRKCAKGMQRL--IEG-SEV--TGQRVLVVEDTCTTGNCALTAVHAVQDVG-MPTIQQLVRKGRRDK------------ICKVKTAALKGC------PQRRGVCTRVYTTTPKKPNCALRKARVKL-TCQVEVTAYIPGEG--HNLQEHCMVLVRG-------GRVKDLPGVRYKIIRGCLDTQGVKNRKQARCRYGAKKEKGVVTMKQLL-----DCGTHFGHQTRRWNPKMKR--FIFTDR--NGIYIIDLQQTLTFIDKAYEFVKETVAHGGCVLFVGTKKQAQECVAAEATRVGMPYVNQRWLGGMLTNNKLERCLGGIRDMAKVPCAIWVVDTNKEHIAVGEARKLGIPVIAILDTNCDPDEVDYPIPGNDDAIRCAALLTRVIAC-AVAEGLQAR???????????????????????????????????????????????????????????????????????????????????????????????KHLFVCGGVACCLGKGLTACCLGQLLTVRGLHVTMQKLDPYLNVDPGTMNPFQHGEVFVTED--------G-----AETDLDVGHYERFLDRNLPGCANVTTGQVYCTVIAKERRGEYLGDTVQVIPHITDEIKRRIDVVITEIGGTVGDIECQPFLEAARQVRHYLGREDVFFLHVCLVPYLAPCGELKTKPTQHCVAALRCIGITPDALILRCDRDVPEALKNKIALMCDVDIDGVICTPDAPCIYDIPKVLHREELCDAYLCVAEALRAHGVLIPGGFGIRGIEGKIGAIAYARARGLPVLGLCLGLQCIVIEAARCV-GLTNANCAEFDPDTPDPVQEEIVAGEADLGGTMRLGCYPAVLEPDCVVAQAY-QTTQVCERHRHRYEVNNA-YRDKIAECG-----LRFC----GTC-PDGHLVEFVEY--PPDRHPFVVGTQAHPELKCRPTRPHPLFTKQDATVEVAIRL-GVDPRK-ADQMVRGTVNLPHGTG-KTARVAVFAVGEKADAAVAAGADVVGCDDLIERIQGGWL-------EFDAAIATPDQMAKVGR-I-ARVLGPRGLMPINFRVDKQANLHFVIGKACFDEKLLAENYGAAIDEVLRLKPCCCKGRYLKKITVCTTTG--------MARYTG-----PVTRKCRRLRTDLVGG--------DQAFEKRPYPPGQHGRA--RIKE-VMEKQFRRYYEEAVRQPGKTGEELLKILECRLDNVIYRAGLARTRRMARQLVCHGHFNVNGVHVNVPCYRVCQYDIVDVILAPVICEKCYGLLD-DNVYTFLVRPDCNKTQIKIAVEKIFAVKVACVNTKRAIVTLAPGC--RPIDLFGAPA?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????MQIPTVTKVVVNMGVGEAARDAKLINGAVNDLALIT-GQKPEVRRARKCIAQFKLREGMPVGVRVTLRGDRMWEFL-DRLTCIALPRIRDFRGLCPKQFDGVGNYTFGLAEQAVFHEVDVDKIDRVRGKEALADPNDACTAKC---RDQLDDDMLLVGPPGTGKTTTAEALGKIYAGM-G--IVRHPEI-REVRRCD---FCGHYI---G------ECGPKTNEL--------IEKCLGRIIF-----MDEFYCLIERHQDGTPDMIG-------MEAVNQLLVQLETHRFDFC--------FIGAGYEDQVDEF---LTVNPGL-A--GRFNR-------KL-----RF--ECYCP-V-E?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????AGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLV-DNGAYPCTLGYKGFPKCCCTCLNEVICHGIP---DCTVITDGDIVNIDVTAYIGGVHGDTNATLVDRTREATMRAINTVKPGRALCVIGRVIECYANRFGYNVVRDFTGHGIGT-TFHNGLV-VLHGMTFTIEPMIN--LGA---------LDVVTKDRKWTAQFEHTLLVTDTGVEILT----------------MVFEAVTLG----------------------------------------------VNDGARIGIVGRNGDGKCCLLGLLTGQLRPDQTD-----TLDP----NRTV--GWTLIGDQPEHQWAG---NPRIRDVVAGLVCDIAWDTPVCTLCGGQRRRVQLACLLVGEWDVIALDEPTNHLDIQGITWLADHLRRRWARN---TGGLLVVTHDRWFLDEVATTTWEVHVEPFEGGYAAYVLQRVERDRLTAAAEAKRQNLLRKELAWLRRPVLRDIEWRIGPGERIGIVGANGAGKCTLLGLIAG--TVQPGV------GV-------LDQHGDDLAPF-ADDRIADVLLCGGQRRRLQLMLTLLCEPNVLLLDEPTNDVDTE----MLTATEDLLDCWAGTLIVVCH--------D
Nanoarchaeum_equitans                                   ??????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DIGGMKDVIQKVRELVE-LPLRHPEIFERLGIEPPKGVLLYGPPGTGKTLLAKAVANEC-----GAYFICINGPEIVCKYVGECEAKLREIFEEAQKNAP------AIIFIDEIDAIAPKRDEAVGEVERRLVAQLLTLMDGLKCRG------KVIVIAATNRPNALDPALRRPGRFDREIEVPVPNEEARYEILGADLAALVKEAAMNAIRGPPGTGKTLLAKA---AACECGANFIAVKGP--EILNKWVDEIDAIAPARGC--DVNRVTDRIVNQLLTEMDG--ITDRGDVIVIGATNRPDILDPALLRPGRFDRGVAHIYCCENNTIIHITDITGAETIAVGCGGMVVNADRLEGCPTAAILAAKRAAALAKERGITGLHIKVRAPGGHNGPWIPGPGACAAIKTLAREGLKIGIIEDVTPTPHDGCRRKGGKRGRRGPTGRFGPRYGLGIRKRVLTVEIKQRKKHVCPFCRC-KAVIREAYGIYRCKKCGKQFTGLAYYPVDKGAVKPILNGADIMRPGIKEYCP-FKKGDIVGKAIKNL-----YQYVRALYKDPKE--FLGELYKQRIQQWRREPPIVEVERPTRIDRARALGYKPLPGIKIVRVRVRKGTRKREEIKGGRRPK--AEYRIRPLGVNLQWIAEERANRLHRNMEVLGCYWVGEDGLYKWYEVILVDPFNPNIYNRPEYVWLLQKNQRGRVFRGKTCCARKFRGLVVALIKDCIHYAPLMVVKWE---NGAQCLLPAPLGICVGDTVGKEAPNAIGCIKPLCEIPEGTKIYMLENNPGDGGKLVRACGDFALPCGQFKTLCANARAVIGVIAGGGRKEKPFVKAGNKYYWACCRNRHWPVVNGVKKNACDHPFGGKRHCN-HC--KPFTVCK-WAPPGRKVGYIGARRNIGIIAHIHHGKTTLTDNLLAGAGMLCE--ELAGDAMFTWWHEQEREREMTIYGAAVCMVHEYEGDD----YLINLIDTPGHVEFGGEVTRAVRAIDGAVVVVDFVDGIMPQTETVLKQALREYVKPVLFINKVDRAIKELQLPPNKIMERLAEIVVGVNDLILDMVVRHLPCPKEAQKYRVPKLWHGDLNCKYGKAMLEADPNGPAVAVVTKVIVDKTCKQETAIARVWCGTIRRGMEVWLLNA-NKKVRLQQVGVFKGIQKIQIEEAKAGNIIAICGVRDLQCGETEAIKHIFDPVVTKAIEPKDPRDLPKLIEVLKLIQKEDPTLKVEIDQECGQILICGLGDLHLEIVEY-RIKNDFKVDIITCNPIVVYRECVKGQA-GPVEGK------SPNKLNKFYITVEKGIIHIGEVIDMVMDAFMQVMDHGPIAWEPCIGLIVKLTDAQLHEDAIHRGPGQVIPAVREAIKLAMKDAGLVLYEPVQVILVDVPPDYIGDVTALINCRRGAILDIQTEEDR-ALIKAKVPVREMIG-FTDTLRCATCGRGVWYLVDQVYEPVPDIVADFLCHLTNVRRKGEDKTAFFPVCNLIIKLVEIMKREGYIKNYRLVD-SKI-IEIELCEY---FNEAN-------AIKPRFPVEYCELEK---YEK-RYLP--ALNFGRLILCTCKGLITNREAKEQKIGGVLIAYVYGDIMVVLVGGPNCGKTYFINQLVPCHF-----------PKEYCYLLKNADLK-------NYGIYNAIGEEIIKRANKILVFTKDT------ENGFRF-----ARVGLDHRLEH----YDMVTVKDVPGQLMVEKLCEVLK-QYEELKPPEWAKFIKTNPANERPPDEPVEVWWYKRVACVLRRVYLLG-PIGLCRLRKYYGGTKRRRHG--MRKRHKVKGCGKLLRYILQQLEKAGLIQWVDCPRKGRAITKKGKELLDKVADAEGLVLGRLACIVAGYR-VKIVNAEKAIITGDPNMVKKEWL-QKVKRGD----YYKGPFYPKRPDNILKRVIRGMLPR-KTARGGKATPGPPIGPALCPFKINPGKVVAEINKLTKEYE--GLPVP-VEIII-NPETKEYKIIVGLPPTCALLMKAAGVTR------GPQRTVH-EWVGNVCMKDVVEIAKKKIDCMPTCCLKAAVKCVLGTARATGIKVENKDPKEVTKEVDEGKVGMTHTIL-------NINGERVFTPVTVLEAPELLVIGAKA-YKKENGA--LKEICCGKELCINDVFKEGQYVDVIAVTKGKGFQGVIKRFHVH--R-RQHKCEKGVRK-VGAIGC-RGPGRIFPTVPMPGQMGYHRRTEYNGWVRYGQVIGPTILLKGCVPGPRKRLIILREAIRGYGIHPREAAELHAVCCGPGLLPTLKLGNYIAVYLGKKLNKPVIGVNHIVAHNEFARYLA-----KAKDP-LFVYVCGANTQFLAIVN-NCWFL-VGETLDMGVGNLIDKVARDLGLEFP----GGPKIEELAK------KG--KNLIELPYTIKG-----LNLQLGGIYTEWVFALILEIAERAGGVACNNRLNDMAEQM-AKENNFKFYRLPCQYLTDNGAMIAYLGYYWYCQGRIKIYCTDLEELNRVVEKIKEIVKQTGVKMRGPIPLPTKILRVPVLRITGHRGTKIWDTYQMRIHRRIIDI-ATDDRTIKLLMRTPLITKPEKIQIQLIDLRPLDPEVIRKLCVVEVKIPEPYDRDGL-PIENGPMDPRM-GVIDPGLRCKTCGGKYGEC---LGHFGRIELARPVYHVKFLN----EIKRLLQYTCPKCPY-------CRQWLEKIPD--EDR----PEWLVLTVILVPPVTARPCIILETGERCEDDLTHKIADIVRINNRIEELLCYGAPEPILEENWEMLQYHVATYFDNELPNV------PKARHR-SGRPLKGLLQRIKGKEGRLRRNLAGKRVNFCARGVICVDPRIDIDEVGVPEQVAKELTFPEIVTEWNLDWLKQKVLNGPECLD-------GANYVERHIINGDYALFNRQPCLHKMCMMGHRCVILPGKTFRLNPATTPYNADFDGDEMNYHLVQNYEGKTEIEFLANV-REHIVTPRYGLAII--GATEDIITGLYLLCGKEVFCALLPCQYKKGEIKPLPGRTIEETLEIEIKGTMILAKCGARGKLLNLIQVVGLVGQQCIC--------GRRMEEGRVLPHFKKGDK-SAKARGFVEHGFADGLDPIEFFFHAACGKDALMDTTLRTPKCGYLYRRLVCVLRD---------MQIIPECPEVDLDKLE-PLAFGLKCLIVYFLIPETC-FNEEQFLDNIKQIEEVVCGPKGEVERKFYHP-LIKLCVNDNK----ITWRCHIKNMLEGVQNPFVYRLKVCYTHFPMRVKLEGNK--LIVENFLGEKAPIIKELPYLDKVKVKIEQNKDETE-IVVECPDKEKAGIVACMIGVDEAGRGPIIGPMVIALVDCKLLTKEQREELFNEIEED-PLVAAACIVAKVIRDREIEKIKE---QTGGRIVRPLIVVE---NGGIIEYLDAAEGILCAAVPYARFNQCARLNRGERTQRQGLYCVA-YPLRFECDVHVAQT-LQKPVRTIVHDLIR--FDERPA--------GYNMVVAYEGYNTQDALVINRNAIDFGFTRTMYFRPYEAVERKYALGD-EITVP--SPDVR--GYKGEKHYRHLEC-DGIVYPEAEVRFLEGGELALLG-AA--TLQKRDCCRCEEEGIVDCVKVRVRIRMERGDKFCCRHGQKGVIGLIVPPCDMPFTANPHGLPCRMGQIIELVAG-------KGTETMYDPITGEEYKVKIFVGVMWYHKLKFLAANKLHARARGPMAILTRQPTEGKCREGGLRFGEMETDVILCHGAAICLYERF--GCDLVKVPVCEK--CGYAFKLFLDELTCLGIWPRL??????????????????????????????????????????????????????????????????KTCIARAYFREGNGIIRINEVWQN-PLARARVKEPDINVNVFGGGWHCQTEAVRQAIARLKKAFLEYDNWLLVNDPRRKEQNK--SLRCKPRAWRQTCYRTKNLVKGQKVYTEREWIPFRCKLLYLGIACGTTACHICDIIGEEGIIFGVEFAPRVAQPHQVEIFLKNAIGF--LAVKA-----RCIDVTKDPKVIFRE-VERKLVFYNPLCCIG--RDDINPIAIEYIKKNDIDPFGCATPYLYLINNT-SK---YLAITYTDTAVWTGEKHRKAYIRYNFNVI-KTPIKHEIGVRGLVAHLINKGAEIERALI--PIYAHCAYHYYRVYMLKRKGCNRIEKLKC-QIGLYGPPGTGKTCCVYALALKKIVTNE-------KIKICDKILWDIAYKCGGDLRAAINDLDPGLRDYINLKPMLIPYCGGRHQKHRFGKAKIPIIERLAGRLMGKKYNAYKIIIRTFEIIEKRTKQNPLKVFVKAIENAAPREETTTIEYGGARYPKAVDCCPQRRVDLAIRHMVWGAFHGC-RKKPICIEEALAEEIINAYNNC-LK-SYAIKRKLEIEKTAECARKG-ERHARRGYNDRNRNAGIRGGRGKAGY---GKMKDH-KKCIYIPA-----------KGFKLIGRLTKPYPIVVKAKYIAETTKENLQCLGIGYTLQELE------QMCLEELAKIMPARQRRTLLRRLKFGIKTHARNTIILPFMVGVTVHVYNGKEYVPVQIKPEMIGHYLGEFCFTTKRPKHCAPGIGATRCCAHVCKKADNCGAKVVKLIAVKG-Y-KGRKRRLAKAGIADLVIVCVRDGKPD---MIGQIFKAVVVRMKKEWRRRDGTRIKFEDNAVALLKDDYGT-PKGTIIKTPIAKEVAER-WPDLAKIARMAAEILKVGLDRVWI--DPNHLKEVAEALTKDDIRELIKRGIIKKLPIEGQCRKRARELHEKKK-KGRRRGPGCRKGKRTARA-DPKRQWINKVRAQRKLLKELKEKKI-IDNKTYWDLYKKVKGNLFKCRCHLWQPKTKLGRLVKEGKITNIDEILCNKYVIREPEIVDVLL-PNLGNKTRYEVIAIVGDKDGHVGVGLGRCCDLLIAREKAINRAKLNIIKVARGCGCWECACGAPHCIPYQVEGKCGCVRVILKPAPKGVGIVADDEIKKIFRLAGIKDVWVRCFG-----KTKTKMNHVFAVFDALEFIRLYLRGANVCKVIIRQT-PIVNRVIIYCARPKMICEERKAHLAKL---LELKFG-LEKPVIEVLPI---ENPNLDAHVIAERLAMGIERNIRAYRRLAQRYLETIMNA-GAIGAEIVIAGRLCG-QRGKTWRFKAGNLRKTGTIGQFELDRAFNIAYLKPGVAGIHVTILKP--DAEIPDVMQYLTCEAKQRLYNIKMAHPEKYELALQILYRVIQ--QTPTIIDDTTLKKLLHGGTLDPKVTGVLPIAIGEATKVLQTLLIAGKEYFVGTIIQTPPLRCAVKRPRKKKVYCIKI--IGVYIRKLIHDIGVKLGVGAHMQELRRIKCGPFHENNC--VYLPVEEAVKHLKKIYILDCAVAAIVHGANLAVPGVCIHTLKGELVPTIKKPKYLTNL-DRL-KWCAIAVILYLLLCYTPLIGG--SIVCLGIGPIIIGYLLAELFIGC--GELNIDITT-EEGKRKFENLARQLML-GVILAYLLDDLCQKG-----FTCGINLFILATVIVLVILLCVYFYMVKIPIPEVRLIYTGNIPVIFCIY--FVLATGQDC-EGLAKQLCKMFGRI-GLKRDYRIIKHYLDKIIPCVTVLGGFIVGFLALLCYWV---SIPI-------GGTCILLATMICYMVYEQLKETGILKELT?????????????????????????????????????????????????????????????????????????????????????????????GLFAGRKLKKIRKKFRWNDYRYVRRML-RIKEKYDPLEGA------PMACGIVLEKTDVERRQPNCGRIKVRVQLKKNGKVVTAFTPGDGAIKVIDEHDEVLIVGIRGRQG-RCMGDIPGVRYKVYL--VNGQPLELLRKGK----IEKARRLVPINVYV-----KAGIHIGTRHL--TKDMKP--YVCKIRE-DGLAIFDIRKIDERLRLACKMLCYY--EPNEILVVGRRETAITPIKKFCEITKVKAFPGRYPPGTLTNPQLKYYME--------PEVILITDPIMDKNALHDAYECGITILALCDTNHTKNYIDFCIPANNRGCKCLALIYWILAR-EY---LRNRKQVIVCRK-LDIGKGKLCAQVAHAWYREGAKKVVLKVNCLEELLDIAKKAMEKGIVVCIIRDAGKTQVCPGTIICIALGPDEDEKIDQITGNLKL?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????RRFTQTFELIFNLKNVDLRK---YRLCTYIVLPRGRGKKMPILAIVGPENKELAEKYF--DIVLTREDLKQL--DKRTAKKLAKRHYHVVAQADLMPELGKCLLGRFLGIRGKMPVRVNVKKHVTFGVPIGTEDMEDEAIAENADTVINEIICQLPQGKQ--NIDCVYLKLTMGM---WRQ-RRKWEG--PCHPWQKQRLIIEKRLMKEYGLK---NKRELWIAETIARKW-RA--YARYLLKKLGVL---SENAELDDVLDLTVKDVLERRLQTMLVRKGLAKTMKQARQFIVHGHIMVNGEVVDAPCYLVKKEEEDKI-MMLLQTEKALRLLEQYNTITILVPREYTKCKIKEFFEKK-GYKVKKVNTKKAYVRFKEEG--VARKVAEELGLYNLQACQVGNIEL-PPQFNEKIRFDVIKRAFLAIQCHKRQPYGACPIAGKQHCAWTCKRRRCWRTCYGRGICRVC-RAILRRHGALFYWV-ARNIAQAVKGKKAHPPKAEKDWYEKINKKERRLAIRCALAATKELDLVKARGHIIDK--PV--PIVV-DGLEQ-LRKTKEIQQLLLKLGLEKELERVYEI--KRRAGKGKRRGRAYIERKGPLIVNIPGLDIEEVPNLNVELLAPGAKPGRLLIICKDAARLKIGKETFEVYVDFEEAIKLK--EGK-P-YDKEKLLLVPEIFRNVKTGERQCEEVLKKVFKTTDVYVIAEQIIKKGQLQIPTEYKRKIKEELKRKIIELIRKNYIDPR-TGLPYTYQRIELAMEKAKINIDITKPAEAQLECIVKELKKIIPLKGEKIRIVIKIPNEYIYKAYCYIKCF---RPQKEEFCDN--YYAIL-SLPAGIYQEFIEKIEKLTEG?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????TDVNVRKLIRQLEKT----KRPIFKYIAELLCKPKRRKKHFVVNLWKIEKHCNDG-----DTIIVPGKVLGCGELTKD-VKVVALCFCQTALEKLKD---KA--IYLENFVEQAKDKKLPNTKIPIRCFCCGKPLGHLWEEFNERV--NKGE---DP-----KKVLDDLGLERYCCRRTLLCALKVGNYIYN----EQDGEVYKIVCIETCKPGKHGCAKARIEAICVTCGKKIVIIKPTCDPIKVPQIKKIKGQIQVMDLETYEVGANVIVWD--LGVPVVKYIIKAEFEIDGIVDI-----IGAFGQTEGLLGMEL----DLRELQKQGKLGRIA---AAIETVDR--------VGPAKARFRVKEIVDVRCCKREYIRNRAVEKCDEIILVEGRAD------VVNLVK--HGILNVLGGIN--IPKCVVELCKRKKV--TLFIDGD--------RGGEL------VLRNLLAAGADID---YVAVAPPGR-EVEELTNKE----ILKALETYAKI--KGKYQLILALD----SNVNMRKIRIEKVTLNIGVGEC---GEKLDKAYELLKRLT-GQKPVKTKAKVRVEQWHIRPGLPIGVKVTLRGEKAYKILKEKLLP--AV---DFK-IKACCFTDRG-FGFGIPEYIMIPGMKYDPELGLIGRIVAVKPPEVTIVRP-VKKLCLEDYILIAGAPGMGKTTFAQALAMFYVKL-NK-VVKTIECPRDMDLGK---EVTQYCLTQG------KTREIYALL--------LLARPDYVLFDEVRTERDIKLFADLRLAGI-GMIGVIHANRAIDAIQRFIGKIELGVIPQV---VDTVIFIDKGQIAKVYTLDMVVKVPTGMKE--EDLAR-------PV-IEVRDL--YTGKLEY-EGRDNRLITGR-IHPRARK-KRKYELGREPTFTRVG--ER--KIKKIRVRGGNIKIRLKRDMYVNVYDPTQGKTVKAKIVRFLDNPCNRNFARMGILTKGAIVETELGKVKITCRPGQDGVLNGVLAGRIAKEAREYAQKLCKCITDGLELAIKVEEFIK-K-RAKLA------FP--VNVCIHNVAAHFCPI----EPIEMYGVVKIDLGANVDGYLCDTAFCLVEACKKALENACKIMRYGVTLCEIGKTIEETIKCYGFNPIKNLTGHCIEYNQLHGGLY-IPNG-LYAIEPFAT--MGKGYVRNGPPCNILIEEKP--VCQFEHTFLVLKDKTIITTCK-PNKCN-YECYNFCPIDECICIG--CGLCVKKCPFKAIKIINVPEAKGE--VVFQYGPNCFRLFCLPI-VKMGKCIGILGPNGIGKTTAIKILCGQLKPNKIQ-----EIQK---LREVF--KGKTVRELIK----------LDNPLLKEFGLDKILDRKIENLCGGELQKLLIYACLCKEGDVYIFDEPTNFLDIRERLRVALKIKAL-------NKTKIVIDHDLLILDYIVELIHIAYGQK--AAYGKFCQPKGNNTAINEYLKG----YLKCENIRIRFKLEAEKGE-VYKKEIIGIVGPNGIGKTTFIRALKGDFDVKPIE------KY-------KPQYI-EPK----EVTVRKLFLCGGELQKVITAAALLKEADLYLIDEPTAFLDIEERVRIARAIRNIIKEKGKAAFVIDH--------D
Nitrosopumilus_maritimus_SCM1                           GAT-VACCGGNPLTT-----QDAWHGQCVKEYDWCIDQVLK-----HKPTILTDDGADMNVKAHGATEETTAGVTRIRAVENQGKLRYPVILVNEAYTKHMFDNRYGTGQCTIDGYLRAMNLLMACKRVVVVGYGW-VGRGVAARCHGMGCK-VIVTEPVKALEAHMDGFEVM-PMAQADIFITCTGMTCVIRKEHILKMKDGAIMGNVGHFDVEIDCEFLLKK-SKCVKEVRPA-LDE--------CVLKN-GKKVYLIGQGRLANLVA--AEGHPPEVMAQCFCNQIINVPEEIDTQVAVDALKAMDVKIDKLTPEQVKYANCWDIGGLTDEIKKVREMIE-LPLRHPEIFEKLGIEAPKGVLLYGPPGTGKTLLAKAVANEC-----NAHFICICGPEIMCKFYGECEARLREIFKEAREKAP------SIIFVDEIDCIAPKREEVTGEVERRVVCQMLCLMDGLEARG------KVIVICATNRPNAIDPALRRPGRFDREIEIKVPDKKGRKDILGADLEYLCKEAAMKCLRGPCGTGKTLLAKA---VATQCEANFVCVRGP--ELLCKWVDEIDCIAPIRGAG-GETAVTERVVCQLLTELDG--MENMHGVVVLAATNRADMIDPALLRPGRFDK---------------MTDLTGGETVCICCGGIHVNADRYECCPFAAMKAANQVVECAKTKGFTGFHIRVRAVGGV-GCRVPGPGAQAAIRALARGGFKIGRIDDVTPIPHDTTRKKGGKRGRRG----LGARYGIKIRKQYTKIHLQLKEKRACPECGC-KTFGRDAVGIWCCKKCCFKIAGTAYDVVDMGAVKFMCKGANLMRPGIRCFT-EFEKDKLVGEVLKNLHYICDPCRQDQVWIRLWK-ENAPEL-RERVVGWRKQNAVTRIDKPCRIQRARRLGYKAKQGVIVVRMRVGTGGMRKQRPTGGRRPKHLGVTRIKA-DDNMKTVAERRVCERYPNMKLLGCYFIYKDGKHYWFEVILADPDHPRVAQDKEL--------TKR--ICQTA--------IIDLVHERGREAPLAKVRFE---DGCVCFVPAVLGAKVGETLGLKCKIEKGNVICIQNIPDGTIVCNIEKHFGDGGAIVKCAGTDALPCGKFTTLNPKNRAMIGTLAGGGACERPFMCAGGKWRNFKAKGKKYPIVRGVAQAAYVHPHGGGRHQH-VG--QCCTVCR-DTPPGAKVGCIAARRNFGVIAHVDHGKTTMCDCLLAYCGIIAP--SAAGKALAMDFDKEEQQRGITIYQANVTLLFQQKDKE----YVINMIDTPGHVDFCGRVIRCLRAIDGAVVVCDAVEGIMTQTETVTRMALEERVKPVLFINKVDRLIKELRLTPEKMQAQLAEVVCNFNQLILGMVVKHHPAPAEAVKYRIPQIWKGDLDCDVGKALLCCCDDGPTIMMIVNMVLDPAAG-PVAIGRLFCGTIKDGQTIQIIDE-KREGRVQCVNFFMGNQREQVGELGAGNIPALLGLTEARAGNTEGVKYVCEPVVQVAIEPKHPKDLPKLVEVLKQLTIEDPNLVVKIDEECGETIVAGMGVLHLDVATH-RI-QDAKVEIVTCEPLINYRETVKAGC-EPIMAK------SPNRHNKIFMKVEPGVQFVQECTDCINCGFDEVMKEGPLCKEQMRDCKFTFTHFVPHEDTAHRGLCQLGPACRRACMGALLTAGTAVLEPTLAIEVRVPTDLVGNVATVLCGKRGKVLDMAQKGAC-SIVTGEIPACETFT-LCEEMRGQTAGRATWNTCFKAWTEVPNILANLFVTLYNNETRRKGECTILPTCKLGIEVLKTLQKDGYIGEFEHID-DGK-FKIKLLAK---ITKCG-------AICPRFKVKTDEFNN---WEQ-QYLP--AYDRGMLLVTTNQGVMCHHEATQKGIGGFLIGYVYGDATVVFIGLPCVGKCTLLNRLTPGII-KGACTGKGLGKRILC-VARTADLH-------LYGIVCALKEKIYEKLKFIRIYMRPKGGETDFKEPFRY-----GMVGLCHILQD----EDMAKVYDVPADVLIGKLAEILKNED--IPAPCWIPFVKTGAHADKPPQNR-D-WWHTRCACIMRKIYLHG-PIGINELRKDYGGGKP--SG--YGAAHHKDAGGAIIRNAIHGLEKLGYLEKVEK--KGRIVCKQGMQKLDRLADATNHIAGRLCCNVAGHR-VCIVNCEKIMYCGTRCNLIKEYR-EFLEINCIINP-KHGPVHYRRPDTIITKMIRQMLPYDRKPCGGGACAGPPLGPALGPLGVNIMEVINAINDKTKDFE--GMKVP-VTVIV-DCDTKKYEIEIGIPCAAALIMKEAGIQK------GCGACGT-EWAGDVTMDAVVKVANTKLENCYACCLKCVAKTIVGTCLALGVKVEGKTPKEITAEINEGKAGCVQIVCIDDREKVPNAGKQLVCLGTVLVTPPVLILGIRG-YCKDHDG--LHAEFDGKEIKIDQIFETGACVDVAAITKGKGWQGVLKRWNVK--K-KQHKCRKTVRE-VGCLGP-ICPQCVMYTVPRAGQFGFHQRVEYDGFKHFGLVKGDFIVLKGCVPGAYRRLIKLRCQIRGEGIHPREACRHHCYAGGPGLGPCLRVGAVVARCLACFYKIPIYPVNHALGHIELGKLLT-----GATNP-LVLLVCGGHTMLLAFLN-KQWRV-FGETLDITLGQLLDQFGRCIGFACP----CGKNIEELAT------TC--SNYVTLPYCVKG-----NDVCFCGLLCETAFAMIAEAVERAGGVAANKRLCEMLQDV-CKRHGAKFFVVPLKYAGDCGCQICWTGLLECQIKRVKLTCTCLPKLDGVCGEIMGIGKKTGVKVKGPTPLPVKRLHVATRKCPCGNGTETYEKWEMKMHRRIINI-NADDKAIRQLMRLKI---PDDVYIELIRFCVWCPTEIRKYCVAEITAPETYDEDGM-PVQGGLMDGRL-GTLEPGQKCLTCGNTAARC---PGHFGHLELAEPVLHIAFID----NIYKLLQCTCRCCPH-------CRERFCQIID--EDR----PEWFVLQAFPVPPVTVRPCIILETGIRCEDDLTHKMVDIIRVNQRLKECKDAGTPPLIVQDLVDLLQYHTTTYFDNEVCGI------PQAHHR-SGRPLKTLTQRLKGKEGRFRGCLCGKRVDFCCRTVICPDPNLDLCEVGVPEAVAMKLTIPEIVTEWNIERMRKLVINGPEKFP-------GVNYVERHLADGDIVMFNRQPCLHQMCIMAHYVRVLPGKTFRLHPCVCPYNADFDGDEMNLHVPQCEEARAEAILLMRV-QDQLICPRYGGPII--GALRDFVTGAYLLTGKQLFCLFLPNGYKKGTLKLTRGMKPEEALEAYINAGKIMATTGARGCCLNVGQMAGALGQQCRR--------GNRLHEGRALTHYQEHDD-NPDAHGFVKCNYREGLCALEFFFHAMGGREGLVDTAVRTQQCGYMQRRLINALEHMAQ--LLFITKILPEGTDVDLDKLE-PLAFGLEFLKAEFVLEDKE-GQCDALENAVKNTEGVFEGPLGKTHKNFRNI-PVKIEIADGK----VTARCIIRNICEGLVEGYTIKMKVVFAHFPITVKVEGKK--ILIENFQGERAPRCTHIM-G-NTKVIP---KG-ED-VLLTGEVWTDITQTAANIGVDDAGRGCMLGPLVICGIDCKKLCPKCRELLYKQIDCRFVVVCAACIIAKVTRDRAIEKLRK---TY-GRVLRPLIIIK---DNGVLEMIDANEGAGACIIPYPEHNQCPRNTYECAMAKQGFCTPM-MNTCTYVRQHFMLY-PQVPVNTKAMKLLG--LEDRPA--------GQNCVVAFDGYNIEDAIVLCKACVDRGLGRTFFFRIYDAEAKQYPGGD-AFEIPNAEDNIR--GYKGERAYRLLEE-DGVVATEAPVRFM--EEYREFE-SC--GPYRRDTCRPCETGVVDTVMYKIRARDMRGDKFACRHGQKGVLGILAKAEDLPYTANPHAFPCRMGMMMECICG-------KGKEIMYDGRTGKCFPVEVFIGVVYYQKLHHMVADKIHARARGQVQMLTKQPTEGRARGGGLRFGEMERDCLIAYGACMILKDRLLDECDKCDIFVCER--CGYAFKLLLQEMQCLNVAPRLDDGLFIDCLNGFPGPYAKLDGTICKCQKGK--GWGYDPIF-IP-------KNCR-KTFAEI--NHKKTCCAHVYITKGQGKVRINEMIPQ-ETAREVILAPDICVRVRGGGFMGQACAVATAICRLRKRITDYDKYLICGDARRKEPKK--FGGPGARRRKQKCYRTENLVPGNQVYKERLWDPFRCKLLYLGACTGTTVCHICDIVGPCGIVFAVEHACRIAQPDQTEIAIDNGYFF--LVIKT-----RCIDVTKCPKKIVEE-ETQKLAFFNPKARLN--RDDLNPTALKMAEYCDIDPFGCPAAFFDCGIRA-TMHGGILCVAATDLQVLNGLFQCACKRKYGGVPV-RAEYGNEIAIRLVLGCLRMVAARLGVEVE--PMFVECDMHYYRTYVKVRNRPDQDE-----NIGLAGPPGIGKTTMAFLVALENILKKE-------SAKLCPGCLIKVIDKCRGDIRCMINLTDPGLKTAICLRKQILPYTFGRCALKRFNKADVNIVERLINKTMGKKTKVLNTVRTAFTIIELKTGKNPVEVLVRAVENCAPNEDTTRIVYGGTVYHVCVDVAPIRRVDLALRFIADAIKECT-FCNPKPIEEHMAEQLILAAEND-PN-APCVKKKNELERIAQACRRG-GRHMGWGQVGQHRACGHKGGLGVTGM---MKHHWC-TTLKDEPD-----HYG--HDCTKLLGGGKVCNAYCVKVTQYTACAEEKLKAVGGGIPKEELD------NMCLEKLFQLFNARQRRCLTR----GIKTHVRDLIILPYMVDVTVNVFCGKEFRPVTIRTEMIGHYLGEYVITNRKVCHGAPGVGACRCCLYVPLKADNCGAKILEVINVPR-H-RTRACRLPCACVGDFCNVVVKKGPAE---LRKQVYGAVIIRQKYPVRRLNGVRVCFEDNAAVLITPE-GE-TKGTDIKGPVAAEACEK-WPRVANLARLACRVTGVGVHRIKF--DADHLTDVADAITRENIRCLITANTIKIDCFTGTCRGRAQTKKAQRNKRGTKQ--GCKQGRKGARV-GKKEIYVAKVRCLRRLLKIAKDRKE-LTNPEFWALYKKVGGNTVRNKAHLWVPKTILGQKVACGEICCLEEIIELGLRIQEAGIIKKLL-PDLGQCTRFKAIVATGNENGYLGIGQGKCKQMRIAIEKATNAAYLNVNPIKMGCGCWECRCDQKHCVPFKVKGKGGCVTIEIIPAPRGLGLVAGGKIKRLLELAGLKDAWTTAKG-----STPTMNCTCKAILDCLDYLRDAIKEAGFCHAEICKT-PTGTRVALHVTRPGIVIGRKGCGIRDLTDKLATDFG-LKNPQICVVEI---EKPELCPCVMCNRMACHLERGTA-FRRATMWTLKQIMEN-GAMGVQITICGKLRG-DRCAFEKHTAGILPRAGHHAEVIVAEDIAHVGTAMGLIGIRIRIARK--E-KFVPLKQILVPEARMRLNNIKMVKPELADLVEQYLIGMATQGKIPGQITDDQLKQILHCGTLDPQVCGVLPLGLGEATKALGVLLFGPKEYLTGEIYQKPPQRCAVRQTRTRTIYEFEV--LGTYIRKLYYDLGEILGPGATMIELRRTRVDQFRETDGL-VTLPVEHALCELKCVVIRDCAIDAMCHGAQLAIPGVGIYTQKGEAVPQVPKPKKKIPLCTRL-LWCGVALLIYMVMGQTPLFGG--TLVELGIGPIVTAGLLMQLLRGC--DILKFDFKK-PEERGVFQTATKQLMA-ACIIIMFLDELIQKG-----LGCGICLFIMAGVTAGVILILVFTQGMKIEIPPIKMMYVCNIPVIFGRL--WVELGGLCP-KCAAQNLLDADVQIPGFRRCNKPVEALLNKYIPCVTIIGCAILGLLAGACDVL---GVFG-------SGIGVLLMVDILINYYTQLVREQVEVVMPLHQKGIIKFGD---FTLACGKKCYVDLRLVPCYPP--L--IYVRCKPKGTCKC--VEG-KIH--DGMQVVMIDDVATTGGCVVNAIKCLKEVNGLFAGRVLTTKKKRQRWAICTYKRREL-GIDKKADPLGGA------PQARGIVLEKVGVAAKQPNCAIRKVRVQLIKNGKTVTAFLPRDGAMNFIDEHDEVHIQGMGATQG-GAMGDIPGVRFKVFK--VNGTCLHELVIGK----KEKPRRTDIKKKIL-----STGIRVGTQVK--TKFMRP--FITKACP-EGLYMLDLDITLDKIKTAAKFINRL--GVENLIVCCGRQYAETPIEKFCETLGCKKLLGRFMPGTLTNPCLPYYIE--------PKLVLICDPQVDEQAITEATNAGIPVIGIANTDNITCNLDVIIPANNRGRKALATVYWLLVR-QI---LIEKKQVIVVRTDLEMGKGKIAAQVGHAWWG-GQEKVVVKVCGIKDLQEVKKHAIDLNLPWCEVTDAGHTQIAPGTTTCICIGPAPENLIDRVTGDLKLKFIFVTGGVMCGLGKGVTTCCIAKLLQLADQKVCCIKIDPYLNYDAGTMNPVAHGEVFVTDD--------G-----GECDMDIGNYERFLNQDIPKCHNITTAQVYCCVIEAERKGEYLGACVQIIPHVTDEIKNRIDFLIVECGGTVGDIECLPFLEALRQMRVEEGPEGVIFVHVTLAPCLDVVGEQKTKPTQHCAQELRRIGIQPDFLAVRCTLPLEEKTKKKIAMFTNVTAKDVLCCHDAKCIFEVPQMLYDQGLADCYVCVNHALKHDGILVPGGFGTRGCEGIIQTANYARENNIPYLGICFGFQLAVIAFGRNVLKLDDANCTEIEPNTANPIQKDV----SDMGGCLRLGANEVLIKENTNAQKIY-GTTTICKRHRHRYEINKE-YIPKFEENG-----LIFC----ADC-DNGKRMEMLEI--PC--HKFYLGVQFHPEFNCRPGFPEEAFKKFKQCIELIVNFKDIDVKK--GFALNEVVQLPKTC--SPATVCVIATGDMGTKAKAAKADCVIGNEELDKFGANKRECRKFINKYDFFLADTQIMPTVGKTL-GQLLGPRGKMPIKVRTRACLCVCCKIGDETMEDADLAINAHAVLCAIEKKLPNGEK--NMKRVMIKTTMGMGDPKYP-RRVWRK--PKRPLNYELKMEELKTLGTFGLR---TKRELWKAHTELCRV-RH--QARCLLARIGLV---SCDATLDDVLNLTANDLLCRRLQTIVTKKLGFKTPYQARQAVIHGHIMIGERKVDIPCYTVTVEEENCIILKPYITEKTFAMVENECKICFIVERCACKPEICEAVNTLYNEKVLNVNTKKAFVQFENTE--KARDLATKIGVYTTTGTKDGEVEL-PAVFCTPFRRELIHKAFTNLTCHKFQPQGRHPTAGQDVVA------DCNDPPTGQGVCRVA-R--AQGGGGGRQGQ-GAEVACTRGGRQAHPPIVEKVIYKKLNKKEKKLALCCAIAATACKDRVECRGHKVEGIECF--PIVVCDDIEC-VCKTCEVCKILDCLKLTQDVQRLETR--KARCGQCRLRGRCKKVGKCVLFVALPGVEATCVKDLCVLDLAPGCDPIRLTVYCKCAARFCFEGEKFEILVKPDPALEYK--LGK-K-KDICAILVCEDIYTDCGKGTKPCTEKLLKAFKTEDQTEIAQIIMQKGDLNLTTDQRRKMIEDKKKQIVAYIAKTYVDPK-THLPHPPLRVEQAMKDGRVCVDPQKCVDEQVKDIVDKLRCIIALKCENLQLEIIIPAQYACQCYAVLKCVG--SLKKEEWQNNGCLKAIL-EIPAAARPNVIDRLGCITKGVRRIKEGTVIDHIDEGKG--------IQVLNALRIDG-SDGCL--ITIALNVPCGKFK-K-KDIIKVENKFLKDDDTNKLAVIAPKATINMIKDYKLVEKRRVCLPNEIDRI--FRCCNPDCVTNCT--EHIECIMDVI-DKE-GRVLKCRYCTNQVVIRMAKDLKCACAKNDAPIWAKLAEYALKPCIARR--DINLNKIAKLTKEN-----DTVVFPGKVLGTGNVPHK-ITLCCFCICNCAATKIIENGGKL--ICYCELIE--QNPTGKGVVLPVRCFTCGNLIADKYDDYQNKI--KAGE---DP-----EKTLECLGIERYCCRRMLLTTLKIGCYILLPHCDQPCGEPCRIVEYDTCKPGKHGAAKARIVAEGIFDGQKRPHVGPVCMQIHVPMINKKVGQIQLMDCETFETGQNVEYWVV-MDKTKIKYHVKLCYEVDGLVDI-----IGAFGQTEGLLGPEM----NLNELQRVCKVGRIA---AGIECIDK--------VGPFDCKFTLEAIDDVRAAKKDDIVKRALADCNWVILVEGRAD------VINLLR--AGYDNALAGAK--IDECIKELCNCKETV-VAFLDGD--------RAGGF------ILKELKCV-VPID---YELRADNDV-EVEELTPQR----IDEILEGAKNA--GIECVVGHRVA-KL--SNCMKKICLEKVVLNMGVGKC---GDVIEIACRALEQIC-GKKPCARNAKETQRDWGVRKGEPIGVAVTIRGDDAKALL-KRLLE--AK---GNT-VNGRAFDNFGNYCFGIREHIDIPGVKYEPCIGILGRIAITHPPEITIVHP-IIQMCLEDYIVICGAPGCGKCTLACGLANFYHNK-GK-IVKTFECPRDLQVDP---GITQYCKLDG------SFDNTADIL--------LLVRPDYTVFDEVRRREDFRTFADLRLTGV-GMVGVVHANCPLDAIQRFIGKIELGIIPNV---LDTVVFVKDGQIKKVYDLELKVKVPCGMTE--SDLAR-------PV-IEIRDF--ADNTLEH-ENLATCKTTGG-RRHPLRI-RRKYETDRYPNEAVTG--AQ--VTVTRTVRGKNRKTAVKTIDFVNLAT-GDAKVKKAKILKVLDNTTNNDYKRRGIITKGAILETQEGKCKVVCKPGQNGIVNAILAGKIACEVREMVRVKDWVGKTVYEICEWVEDEIR-KRGAKCA------FP--VNTCINEVAAHYTAEPNDPITIKDTDLIKIDLGAQINGYIADTAVTLVQAAEEGLANAMCMIKAGVKACDIGRTIETTIKQMGYKPIANLCGHCLEQYTIHAGKC-IPNNCAYACEPFVTTCEGGGFVRNGQIKNILIEVNEQRVAQAEHTFIPTEDGVTVTTCQ-PKKCG-LECIKYCPIDEDICNG--CGICVKVCPFDAITIVNLACELATD-KIHQYGPNCFRLYKLPT-PKKGEVVGLLGRNGMGKCTVVNILCGNLKPNKPQ-----QVHQ---IAQAF--DGT-GKELIEKYDER---G-VCRELIKELGLQNCVDQCLKELCGGELQRIAVAAAACKDTEFYFFDEPCCYNDVFQRTGVARVIQCLAK-L---GKCVMVVEHDLTLLDFLCDYIEVLYGEP--SAYGIVCNILCTKVGINVFLDG----YLPNENVRFRFCVEVEPGQ-VRKGEVLGIMGANALGKTTMMKMIAG--VEKPDC------GY-------KPQYL-QND---VDVEVVALLLCGGELQKVAVACCLLQKVDLYALDEPCAFLDVEDRIAVAKFLQKFVRCFGKCAIVIDH--------D
Picrophilus_torridus_DSM_9790                           GAD-IKMACCNPLCC-----DDARKGETQEEYYDYLNKIID-----PEPDIIIDDGGDLTNLVCGGNEETTTGVVRLKAMEKCNALKFPMFDVNDAKMKHLFDNRYGTGQCALDGFMNATNILIAGKRICVIGYGW-VGRGIAMRLKGLGAI-VTICEPVKAVEALMDGFCVD-TVENADIVFTATGMKNVVPYCALLKAKNGIILGNAGHFNNEIDMECIECK-NICKERVRDY-ITE--------YRLEN-GNRINIICDGRLLNLAA--GQGHPIEIMDLCFCIQVYPVPEDIDKNVAEIKLNALGIKIDKLTDEQIMYMNCFDIGGLCDQLGRIREIIE-LPLKHPELFERLGITPPKGVLLCGPPGTGKTLIAKAVANEC-----GANFYAINGPEIMCKYYGQCEQKLREIFQKAEECEP------SIIFIDEIDCIAPKREDVQGEVERRVVAQLLTLMDGLKERG------HVIVIGATNRIDAVDPALRRPGRFDREITIGVPDKKGRKEILGADLAALTRECAMNALRGPPGTGKTLLAKA---VANECNANFICIKGP--EVLCKWVDEIDCIAPRRGAC-MDCGVTERIVNQLLTCLDG--IEVLNGVVVIAATNRPDIIDPALLRAGRFDKGIAHIYACQNNTIILVTDPTGAETIAKCCGGMVVKNDRDEACPYAAMRAADMVCEKLREREITDLIIRVRAPGGC-KCKIPGPGAQCAIRALCRAGFKILRIEEVTPIPHDGTKKKGGRRGRRGVAGRFGPRYGVTVRKEWCKYYVQKKAYYVCPKCKQ-KKVRRIANGIWECRHCCYKFAGGCYNPVDDGAVCRICNGANLFCPGIVCMDMCMKKGDITGIAAENLHYLNDYCMIRDCWKKLKK-SDIYPVQKARMVCWRKCGCVVRLDYPTRLDRARCLGYKAKQGFIIVRCRVRKGGQHRPKIMGGRRPRRLAYNKLTV-KKCIQLIAEERAADKYPNMEVLNCYYVGEDGLYKYYEVILIDRCCPAVLCDKNVCWIANCANKGRVYRGLTCAGYKCRGLIEDIIQAPGRNTPVLLIRNE---KNEKNYMIAFNGAYVNQEIGDIDCPAIGDVTYLANIPDGCYVYNIECIPGDGGKFCRAAGTAALPCGVNKEFHPRCRATVGFIAGCGARDIPILKAGTHIKYLQCKAKRPYTVRGVAMNAVNHPHGGGNHQH-VG--RPCTVGR-GTPPGRKVGRLCPKRNIDIAAHIDHGKTTLCDNLIAGAGMMCE--DLAGKQLLLDYDEQEQARGITINAANACMVHEVDGKE----YLINLIDTPGHVDFGGDVTRAMRAVDGTIIVVDCVEGVMPQTETVVRQALKEKVKPVLFINKVDRLINELKLNAEEMQKRFVKIITDVNRLILDMVIKNLPNPREAQKYRIPQIWKGDLDCEIGKAMLCCDDNGPVCMMVTKIIIDPHAG-EIAVGRLFCGIIRKGCELYVCGA-GK-TKVQVLCMMVGPDRIPIDEIAAGNIVAIIGLKGAIAGCTEPMTHYTDPVVTLAIEAKHTADLPKLIDVLRTICKADPCIQVDINQETGEHLICGMGELHLEVTIY-RIKNDYKVDVVTCEPLVVYRETVDKKG-GPFEGK------SPNKHNRFYFQVEPGIQYLDETMELLIECFNEAMDKGPLANEKVYGLKVCLMDAKLHEDCIHRGPAQVIPAGRNCIYGAMCEAGRVLLEPMQKVFICVPQEIMGCVTNELQQRRGVVEDMQQNGEE-ITIIAKVPVAGMIG-FACAIRCATGGKVIWNCENAGYQRVPDPLNDVINTIKNACRIGKCEVIIGPACVMIGRILKVMQDYNYIKCFEVIE-EGK-FRVELCDT---INNCG-------VIKPRLCVKNCNIER---YEC-RYLP--AQDFGIIILTTTKGIMCHIEARKLGIGGKLLAYVYGDATVALVGYPNVGKCCLLNKLTPGII-DNAALGAGRGREVLA-AVRNADAK-------EFKVVNGLKEKIFDNLDLIRIYMKNKCGEVDYERPFRY-----AIIGLDYELKD----EDMVDVKKVPADLLINDVACKLKCMN--IEQPEWVCYLKDGMGKQKCWDQE-D-WYYTRLACMMRKLYLYG-NLGIMHMCEEYGGKVD--RG--TKRYHPAAGCRYIVRQLFKKLEELGLVKKEKT---GRVLCPQGRCMLDKCADACNHIYGRLCCYVAGEC-ITIVNACKVVITGRKEFIIDKFN-NLRNTGC----IRKGPYYPKTADRILKRCIGDMLPK-KKTHGGKATTGPPLGPALGPLGLNLGQVVKDINEKTKNFA--GMQVP-VTVNVIDPATKKYEIIVGVPPTCALLKKELGIEK------GACKKKE-KIAGNATLEQIKKVAECKRCALLCYNMKGAVLEVLGCAVCLGITVDGRDPKEVQKMIKNGKVGMTHIQMVDYRKNCVTAGQVIMAPVTVVEVPPLTVMCIRY-YARGDNG--LEVICEGCNICFCDFCKPGNFVDVIAVTKGKGFQGVVKRFGVKLLP-RKNRK---HRRMIGTLGP-WHPDWVRNTVPQAGQVGFHQRTIHNGFLNYGIVRNDYVLLFGCVPGPAKRLIKMRDPARG-GIHPREAAVHHAFCMGPGLGPCLRVVCTAARALCIKYCKPLLGVNHPLGHVEIGRKLC-----GARDP-IMLYICGGNTQVIAHLN-GRYRV-LGETMDIGLGNMLDKFARDLGIPFP----GGPVIERMAL------DG--KDLLELPYCVKG-----MDTCFCGIYTETCFCMVVEVLERAGGVARNDRLRCMVNDM-ARDCGYKAYLTDKEYCMDNGAMIAQAGMLMYMHGRICLCGTENKIVDVVCEEIKGIAKRTGVEIHGPIPLPTKRLVVPVRKCPDGEGCPTWDRWEMRVHKRLIDV-DADERTLRQLMRICI---PDGVRIEIIKFALLCPDEIRKMCQVKVITPDTYDDDGY-PIDKGLMDLHM-GVIEPGLRCATCGGKVDEC---PGHFGHIELAMPVVHVGFVK----EIKTMLDCCCKVCPH-------CRERLERIPD--DDR----PEWMVLTVLPVPPINVRPCITLETGERCEDDLTHKLVDIIRICQRLRECRDNGCPQLIIEDLWDLLQYHVTTYFDNQTAGI------PPARHR-SGRALKTLVQRLKGKEGRFRANLCGKRVNFCCRTVICPEPFLCINEVGVPERAAREMTVPVTVNAFNIDVMREWVKRGPNPENN-GKYIAGVNYVERQLNEGDIVLFNRQPCLHRMCMMAHTVRILPGLTFRFNLAVCPYNADFDGDEMNLHVVQCEEARAEARIIMKV-QEQIMCPRFGGPII--GAIHDHITALFLLTGRDIFCLTLPDGYRKGQLQPAPGRCIEDTLEVEIDPCVIMARCGARAKMLNIAEVAGMVGQQCVR--------GGRLNRGRTLPHFKENDL-GAYARGFVKCCYRCGLCPTEYFFHCIGGREGLVDIAVRTCRCGYMQRRLINAFEDMGD--VLVVFRVLPEDVDNDLCRLE-EIGFGLKALNVQAIMPDEE-GMADRVECILAGIEGVIKGKLGEACRIFRDN-YVKAYIEGCC----VTWYCETKLLIEGVTKGFEYHMKIDFTHFPMRVCVRGDK--LIVENFLGEKCPRCAKIV-D-GCKVCV---KG-DR-ITINGIDKRKIGETAANIGIDEAGRGPVIGPMVMAMVDCKLLTRNKRCLIFNDVDRDIKIVCAACIIAKVLRDNEIEKLKC---IYGGRLRRPLLIVN---DGGAIEWLDAEEGVVACLIPYPEHNCCPRITMACAMTKQGLPAAN-YRIRVDTRGHLLHY-PQVPVKTKVMDFIK--YNNKPA--------GQNFVVAYQGYNIQDAIVMNKACIERGLGRCAFFRTYTAEEIRYPGGD-RFEIP--THDVL--GARAEEYYKNLDE-SGIIYPECEVRFL--EENADK--LG--PMRRRECCRPNECGYVDNVIVKVKVRMDRGDKFACRHGQKGVIGAVVPQEDMPFTENPHCVPCRMGHVLEMMGA-------KGEEVMYDGITGRKFKARIFIGVIYYQKLHHMVANKFHARCRGPVQILTRQPTEGRCRQGGLRFGEMERDTLIAHGACMVIKDRLLDQCDGTILYVCGNPCCGYAFKLMRDELCCLGIIMRLDTGLYIDDLNGFPGPYGILNGTICDHECGCM-NFGYDPIF-IP-------DGYD-KCLAELCICEKKTAIARAIIRKGCGKFLINELYPI-EILREKMLEPDIDVNVHGGGNTGQADATRTAMAKLEAEIRAYDRCMLVNDVRRKMPKK--PMGYGARAKRQKCYR-------KRVYGEREWDPRRCKLLYLGACTGTTVCHLCDIC-ICGRLYAVELCYDIAQRNQVQIFNQNAILI--IKIKA-------ICCKEPEKKILKE-TICCIGFYNADQKFN--RDEINKKCFEYIEKNDIDPYGCIVPYIDKAICR-IRNHGYIGITATDLTALTGCNVQKLKRRYNAFAL-NDCFRHETGIRILIAFFVRHAAAMDRGAF--PLICLWHCHYYRIFFKIENGCLNADKALC-MIGLYGDPGTGKTTTATVIACHYILKKE-------GKCLPENDIIRIIKENEPDIRCIINDLDMGLAKYINLNCYFNLHTGGRYCNYCAGKRNVNTIERLLNKLMGKKYCAYRVLKEAFEIVEQKTKQNPVQVLINAIENCAPREEVTRLKYGGIAVPKCVDVCPCRRLDEALRNICIGATCKC-FKCKVPIEECLANEIILACRND-GN-SYAVCKKEEIERVAACARRG-GHY--GRGMKAGRGKGKKGGNGMAGL---GKHRWV-WLLKYDRD-----HFG--VHGFKLLGTGDFDIKCRIKIERATEKAINKLCVHGIGHCLEELQ------NMELNELLPLLPARARRCYCR----QIKTHVRDLIVLPQFVGKTIELYNGNCYIKFEIKPEMIGHYLGEFALTRKEVKHCGPGVGATRCCKFLPLKVDNTGAKMICLIDVKA-L-HTVAKRIPAAGVGDMFIACVKKGTPE---MRCKVVYAVVVRQRRPYRRADGTMIEFEDNAAVLVTPD-GE-VRGCEIKGPVAREAAER-WPRIAAICQIAADEMKVGVCRVWI--DTNCIDQVLDATCREDVRKLIDLHIIQKKQKKGNCNYRLKKRIEQLA-KGRRRGEGCVRGTKYARF-PRKRRWICRIRALRRELRELKTNNK-IDKKTYRRYYRIIKCGCFVCRAQLWTPRTELGRLVANGEIKTICEALHCKLPLKEYQIVDYLI-PDLGRRMNYCITAVVGNGNGYVGVGRGKAKEAAPAIKKAIDNAKLNIIEIKRGCGCWECGCGKPHTLPFLVNGKCGCVCVTLKPAPQGVGLAVGDVVKVILRMAGIDDAWGFAAG-----HTKTTVNYALATFDALEYLRKENDNAGFGGMEMKRT-PYGTNITLYVNRPGLVIGRHGTKIKEMTETLEKRFA-IECPQIEVKEV---NTPDLNPQIACKKIALCLEKGWN-YRKAGNTCLRKMIDL-NAPGVLIRIGGKICG-ERARAQKFMFGKIKYCGEPARCGVEYGFCEAKLKTGIIGVCVRILKC--NYRLPDLRQILCPEARERLCRLKLVRPDLVENVENQLIQLAGMGRINKVICDNELKCILHIGTLDPGVCGVLVMALGKATKLIDIVHRECKEYFTGKIYQIPPVRCAVRELRIREIYNLEL--LGTYIRTLCTDIGYVLGCGGQMAELRRTRTGPFDECMC--HTLPMDFIFIKYPKVIVKETALKNIAHGCDIYPAGVAVYTEKNELVPAIKKAKGHVPFKYKL-MWTGLIVILYFALTNIYIYGG--SLMDLGIGPIVTACIVMQLFAGA--KIFNLDLTN-PDDKAIYQGVQKQLFF-GCYLVFLMDEVVCKG-----IGCGICLFIAADVTVLIFFIVAYFQCCKIELPPLQLLYACNIPVIFAKF--WIETTNMGA-GAVAKQIQCCGMQIPGFRRDPRVMERVLCKYIPAITVFCGAVVGLLAAAADLI---GTVGDT-----SGTGLLLAVGIVIQFYEAMGREQLMEMHPLINCGAIKFGD---FVLTCGKRCYIDIKCAYTDPP--F--VIIRKDDLGTRKR--YIG-SIN--LNEEIDIIDDVATTGGCIMKAAEIIRNNGGLNAGKKLMKCRKTYRWCDRDYKRRVL-NLKKKCDPLEGA------PQAKGIVIEKVGIEAKQPNCGIRKVKIQLIKNGRQLCAFAPGDGAINYIDEHDEVVVEGIGGRMG-RCKGDIPGVRYKVIK--VNGICLHELVKGR----KEKTVRLIPEDEYQ-----KCGIHIGTQIK--SKDMDP--YIFKIRN-DGLYILDIRKTNHALIIAGKMLARY--RPEQILAVAQRQYAFRPVCKFCEVVGCKCIIGRFIPGTLTNPALPNYCE--------AKIILVTDPLADTQAMKEAIKVGIPIIAMCDANNKTDFVDLIIPTNNKGRRCLAVIYWLLAR-EI---LKNR-MVIAVRRDLDLGKGKIAAQVAHAWINTGQKKVVIKVDNLDEIYNLKRKFDELKIINEIIVDAGYTQIDPGTVTCIGIGPADDDVLDVITGKYHLHYIVITGGVICGLGKGTITCCLCYLLKNCGFKVTNIKIDPYINYDAGTMNPYQHGEVFVLDD--------G-----SEVDLDLGNYERFLDTDLTGNNNITTGKIYKCVIERERHGDYLGKTVQIIPHITNEIKERIDIALIEVGGTVGDIECMPFIEAVRQLR---STDDVIYCHVTLVPEIN--GEQKTKPTQHCVKELRCLGICPDILFCRCEKPLGKDVIEKICLFTDVPACGIICMYNVKNVYMIPEIMMRQGLQDAYICHKEAFCHDGILVPGGFGYRGVEGKIIAARYARENRIPYLGICLGFQVCVIEICRCLLGLKGANCTEFDNNTDYPVQCNV----SDLGGTMRLGCKKVLIKDGTIAKNIY-KCDIIYERHRHRYEVNPD-YIERLEDCG-----VIFC----GTD-DEKIRMEILEL--SD--RDNYIATQYHAEFKCRPLNPCKVHRNFLECIEICINLKDVDLCD-PKKRINEEIVLPCGRG-KDLKVALICCEEMKLKAKNA--DYTFCPEDVCKFVDDKKCFKKLANKVDFFVAECTLMCCIGKNL-GVILGPRGKIPVRARCRDRRTFHVPIGTREMCDDDLYNNFVTVYKRIVCRLDKGPG--NIDCIYIKTTMGMGDQKFQ-RKKYCT--PRHPWEKDRIDAERQLLIKYGLK---NKRELWRAQTILTNF-RT--QARTLLCRLNLL---GENATLDDVLCLNIEDILERRLETLVYKKNLALTMKQARQFITHGHIKVNDRVVTIPCFMVEKCMEDCIIICPIVTEKTTLMMEKENKITFLVNRKATKEAIKNEVEARFNVKVAKVNMKKAIVTLAKDF--SAEEVGGRMGIYDLNGEIKGEIEL-PKIFEIRPREDILREAFRAITLCYRQPYGACPDAGMRRVG------QNLGP--NHGICRIP-R--LAGGC-----R-AVLLGCVVGGKCAHAPRCDKVLYKKINKRERKLARFTAIALTACREHIIKRGHRIDEDCNLTFPVIVTNDLEK-IKKTRDAVEFFKKLGLYDDILRCKENK-KIRPGRGKMRNRTYKQPKCLLIVCLPGVDIATPCCLCIRKLAPGGTGGRLTIFTECAARYECHGHRFEILIDPACVDKIR--SGN---IDVEKDMALDEIFKDARKGERAGEECLKEVFKTTDVCQIAIEIVRKGEVQLTTDQRRKMTEEKKRQIINEIVRQAINPQ-TNTPIPAIRIEEAMEEAKFHVDPFKCTEEQVQAVLKAIRPLIPIRFEKTRLAIKMCGEDYGKAYGDIAKVG--SIIKEEWCNCGDYMCII-EIPAGMQGEVIDMINKRCRGICKIRDGTVIDHICAGKA--------LEVLNILG----SNNGC--ICIGIRVNCKKMG-L-KDVLKIENVFLEKEDLDRIALIAPEATICIVKNYEIIEKFNVDMPEKIYGI--VKCCNQNCITNAN--EPVKTEFIVD-SRC-PVTLRCLYCTDCYLKDTIQKLLERCRECGCVFWRDIAIRLCCCRKNYA--TVNLGKLQRIACDD-----DIIVIPGYLLCCGVFNKK-IKVCAFKICEKALKKLNDAGCEF--VNLVDLAC--ENPKGTNIKIPVRCFCCGRVIACDYVRFTEACTKIINETGREPRGEEKAKILDDLGVKRYCCRRMILCHLKVGRYILI------DDCPCRIVDITMCKPGKHGEAKGRIVAIGVFDNQKHCVVYPVKHKVKVPVITKKNAQVQLMDCETFETGMEVPYWEA-MGQRKIKYMIKAKIVTDGVVDV-----VGAFGQTEGLLGDEL----DLRDLQKCGKIGRIA---AALETIDR--------IGPCKAKVEIECIEDVRINKRDRVIKRAIADCDCIIVVEGRND------VLNLLR--YGIKNTIAGTC--VPKTVKELCKCRTV--TLFVDGD--------HGGDL------IIKEMLQV-ADVD---FIARAPPGT-EVEELTYKQ----IIKALDIAYNI--GVKAIYGFKIG-NI-TKKPMREIVIDKVVVNIGVGAA---GERLNRAAKVLELLT-HHKPAFTCAKRTVRDFNIRKGLNIGVKVTLRKDDALCFL-KEAFY--AK---DYK-IPVYCFDKNGNAYFGICDYTDFKGMKYDPDIGIFGRIVITRPPEITAVRP-IKKLDIDDYILVCGAPGAGKCTFVTALAEFYAGK-GK-IVKTMEKPRDLQVCN---KITQYTCLEG------DMEKTGDIL--------LLVREDYTVFDEMRVTCDFKVYCDLRLAGV-GMIGVVHATKALDAIQRFIGRVELGLIPQI---VDTVIYIENGGICQVLTTEYTVKIPAGMKQ--EDLAR-------PV-IIVKDF--LCNKPVC-EGRATRKPCGG-KLRPNHC-KRRYELGREPTLTRLG--DR--ELRKIRCYGGNCKFALLRCDYANVYNPKDKTTRKVKINTVKENCADPHYVQRNIMNRGTVICTELGDARITCRPGQDGVINAVLAGKIGKMALDYAQCLIEPGALFYDVAEKTEAFIR-DNGALPC------FP--VNLCINNEAAHYTPYENDKKKFKTGDLVKVDLGAMIDGYMCDNATTLIDATREALNNAIKMIRPGIELYNIGNTIADTINCYGFNPVKNLGGHGINRYDLHCEIF-IPNDKVIAVEPFAC--TGIGMIHNGMPGNILKEHKNCYICQAEHTIMVLCDEIIVTTCH-PKKCN-HECRYYCPITENLCIG--CGICVRRCPFNAIKIVTIPDELNKK-ILHQYGLDTFRLYCIPM-LCKGKVCAILGQNALGKTTTLNILCGIIIPNKCQ-----YVDM---IPRVV--SGT-VRDILNETN-H---G-NMDEIVCELAMENYLDHDVRDLCGGELQKLAIARCLMKDGDIYLFDEMTCYLDIGERLRVCNIVKRLCE-----SKIVMIVEHDLAILDKIADEIHLVYGEP--GAYGVITQQKCPCKAINCFLEG----YLKEENVRIRFELRINPGF-INREEIIGILGENALGKTTFVKMLAG--VVTPDN------GY-------KPQYI-SCD---YDGTVYEMLLCGGELQRLCIALTLCLDADLYLIDEPCAHLDACYRINVAKIIRRAIENCKKCAIVVDH--------D
Pseudomonas_entomophila                                 GAE-VRWCCCNIFCT-----QDAWKGETEQEYEWCIEQTILKDGQPWDANMVLDDGGDLTEILHGVTEETTTGVHRLLDMLAKGELKVPAINVNDCVTKCKNDNKYGCRHCLNDAIKRGTDHLLCGKQALVIGYGD-VGKGCAQCLRQEGMI-VKVTEPICAMQACMDGFEVVCPFKDGDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKH--WAWEEVKPQ-VHKIHRTGAGTFDPQN-DDYLILLAEGRLVNLGN--ATGHPCRIMDGCFANQVEVLPKKLDEEVALEMVRGFGGVVTQLTPQQAEYIGVTEYIGQPVVREQMALFIQ-AARGR--------NECLDHTLIFGPPGLGKTTLANIIAQEM-----GVCVKCTCGPILERP--GDLAAMLTN-LEPHD-----------VLFIDEIHRLCPVVEEVLYPAMEDFQLDIM-IGEGPAARCIKLDLPPFTLVGATTRAGMLTNPLR--------------DRFGIVQRLGLPMD---DKGAFEIARGTPRIANRLLRRV---------RDFAEVRGK--GEITKAVDE-------RGFDHCDRRLLLTMIEKFDGGPVG--LDNIAAAIGEERHTIEDVLEPYLIQQGYIMRGIAHIHACFNNTIVTITDRQG-NALCWATCGGCGFRGCRKCTPFAAQIAAERAGQAALEYGLKNLDVNVKG---------PGPGRECAVRALNCCGYKIACITDVTPIPHNGCRPP---KKRR????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????VERIEYDPNRTAHIALLCYA---DGERRYIIAPKGVCAGDQLGALAPIKAGNCLQLRNIPVGCTVHGIELKPGKGAQIARCAGACALRCGEMRKVLAECRATLGEVCNCEHCLRCLGKAGAK--RWRGVR---PTVRGVAMNPVDHPHGGGEGRT-SGGRHP------VCPWGFPTKGAKTRRNIGIVAHVDAGKTTTTERILFYTGVNHKMGEVHDGAATMDWMAQEQERGITITCAATTAFWQGCTKQFADKYRFNIIDTPGHVDFTIEVERCLRVLDGAVVVFCGADGVEPQCETVWRQANKYHVPRLAYINKMDRQGADFLRVVKQIDKRLGHHPVPIQLAILDAVIDYLPAPCE-----IPAIKGTDPDHEDKHLERHADDKEPFCALAFKIATDPFVG-TLTFARVYCGVLCCGNAVLNCVK-GKKERIGRMVQMHANQRAEIKDVCAGDIAALIGMKDVTTGDTERMDF-PDPVICVAVEPKTKGDQEKMGIALCKLAQEDPCFRVKTDEETGQTIICGMGELHLDIIVD-RMRREFNVEANIGKPQVAYREKIRNTC--EIEGRFVRQCGGRGQYGHCWIRFAPGGVVPREYIPAIQKGIEEQMKNGVLAGYPLINLKAAVYDGCYHDV--DCNEMAYKIAACMATKQLCQKGGAVLLEPVMKVEVVTPEEYQGDIMGDLCRRRGMIQDGDETPAG-KVIRAEVPLGEMFG-YATCMRCMTQGRACYTMEFTRYAEAPDPLADMLTRIRNAQMAEKCVVCM-PCCTLKVAVAKVLKDEGYIAGYEV---TKPCLCIELKYF---EGR-P-------VIEELKRCCRPGLRQ---YKAVCELPKVRGGLGVCIVCTNKGVMTDRAARAAGVGGEVLCTVF--QVVALIGPNGAGKTTVFNCLT------------GHQIARKG-VVRTFQFK-------TPCFRRCLAYGQQRRLEIARCMMTQPRIIML-DEPMKL-----VMCTPDEIRGN----PD???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DAAGQTLGRLATEIAGDY-IVVINAEQVRVTGAKCCDKMYYC-HCGFPGGIKE-INFEKLIAKAPERVIETAVKGMLP--KNPLGGQANPCPPVGPALGQHGVNIMEFCKAFNARTQGQEP-GLPTP-VIITV--YCDRCFTFETKCTPACVLLKKAAGLTC------GCARPNT-VKVGTVTRAQLEDIAKAKQADLTAADLDAAVRTIAGCARCMGLNVEGV------------KAGMTRIFTEEG----------VCIPVTVIEIEPNRVTQFKT-EETDGYRAVQVTVGEGDLIKA-ELFTAGQLVDVTGQCKGKGFAGTIKRWNFRGQD-NTHGNCVCHRV-PGCIGQCQTPGRVFKGKKMCGHMGAERVTVQC------DAERNLLLIKGAVPGATGGDVVVRPAVKG-GVVPELACRDHAYTAGPGLVGALLVGACCAQALAFAWDIPAIGVHHMEGHLLAPMLEEQ----PPEFPFVALLVCGGHTQLVRVDGIGQYEL-LGECLDDAAGEAFDKTAKLIGLNYP----GGPEIARLAE------QGTPGRFV-FPRPMTD--RPGLQFCFCGLKTQAVVETLTIKCKRAGGVCANKALRACLEDMLACIKGNVYYARP-RFCTDNGAMIAYAGCQRLLAGRIRLKAFDHRLIDQCTQEIVETAKRTGAQVRGPIPLPTRKERFTVLICPHV-NKDARDQYEIRTHKRVLDIVQPTDKTVDALMKLDL---AAGVEVQIIRIGLACPEMIRCWCFGEVKKPETINYRTFKPERDGLFCAKIFGPVKDGVICEKCGVEVALAKVRRERMAHIELACPVAHIWFLKCLPCRIGLLMDMTLRDIEE-------FETKIKKLCK--RLL----PEWMVLTVLPVLPPDLRPLVPLDGGRFATCDLNDLYRRVINRNNRLKRLLDLCAPDIIVRNEKRMLQEAVDALLDNGRRGR------AITGC--NKRPLKCLADMIKGKQGRFRQNLLGKRVDYCGRCVITVGPTLRLHQCGLPKKMALELFKPFI--------FGKLEMRGLAT-------------VLAEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAYNADFDGDQMAVHVPLTLEAQLEARALMMC-TNNILCPANGEPII--VPCQDVVLGLYYMTGRALLFQVVPDGYACGLVT-------QGEKYNKVNCMYMMADCGARGCAAQIRQLAGMRGLMAKP--------DGCIIET------------------PITANFREGLCVLQYFICTHGARKGLADTALKTANCGYLTRRLVDVAQD??????????????????????????????????????????????????????????????VKGAKGTLELNVHC--SVEVTEEAGE----LTTRALVNNMVQGVCQGFERKLQLVGVGY--KAQAKGTV----LNLALGFCHPVDYEL--PAGITAET---PCQTD-ILIKGIDKQLVGQVAAEVGVDEVGRGPLCGAVVTAAVDCKKLTEAKRDALFDEIDCQVPAIAAACILAKVTRDREMCEFELIYPGYGKQLIDELVAVRHL-NECLIPFLEHDDARDCGVCVVARRGGVIDCVDACRIVVRGEAGVDIYNLTKYTRCNQNTCINQRPVCKGDVVARGDIMADGPCTDMGELALGQNMRIAWNGFNFEDCICLCERVVQEDRFTTIHIQELTCVARDTKLGEITADIP----------NVGEAALNKLDE-AGIVYVGAEVKLL----RAIFG-EK--ACDVKDTCPTGTKGTVIDVIVKVYLAIRRGDKMAGRHGNKGVVCVIMPVEDMPHDANPLGVPCRMGQILETHLG-------LGQMQLFDGRTGNKFERCVTVGYMYMLKLNHLVDDKMHARCTGCYCLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKCDDV---------NGECFNVLIKEIRCLGIDIDLDCGLAVDFLGGAPGIYGLWHGCILFEACGEH-GFGYDPLFWVP-------ERK--CCCADLAPVDKKTATARVFLRPGTGNICINDVFFGRETARMVVRQPDIYVTVCGGGVCGQAGAIRHGITRLRGALRRAG--YVTRDAREVERKK--VGLRKARKRPQYCKR?????????????????????????????????????????????????????????????????????????????????????????????????????????VFHCVAAKYDLMNDDINECMLKVGRDRQAD--AEKLPFPDNHFDCVTIAFGLRNVTHKDEAI-----------RCMLRVL-------KPGGRLLV-------LEFCKPTN--KLMCKAYDAY--------------------SFAMVGPPGTGKTLLAKAIAMRKVPVGE-------NVNAA-VIARGTPGFCGADLANLVNEARVAAKREILDDPKY----------------GCQILAKFMNHVMGKKAVAERIVYGALDTVKARKNCDPLEIFEKALDAIAPLVEVKCRRVGGATYQVPVEVRPCRRNALAMRWLVDYAR----KRGEKCMALRLAGELLDAAEGK----GAAVKKREDVHRMAEANK?????????????????????????????????????????????????????????????????????????????????????????????------------------------VP----RCLKK----GVKTWCRRCMILPQMVGLTIAVHNGRQHVPVLVNEDMVGHKLGEFAGTRTYRGH-VADKKAKR--------ADNCGARRVMCIKVLG----GCHRRY--AGIGDIIKVTVKEAIPRGKVKKGQVMTAVVVRTRHGVRRADGCIIRFDGNAAVLLNTK-QE-PIGTRIFGPVTRELRTEKFMKIVCLA???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????----------------------MANNDQKRDEGYI--------GRIFTFTALTVVGDGKGRVGFGRGKCREVPAAIQKAMEAARRNMIQVDLKGT----------TLQYATKAAHGACKVYMQPACEGTGIIAGGAMRAVLEVAGVQNVLAKCYG------STNPVNVVHATFKGLEYLQDKLKCACVCRIDIHRP-AQTARITIHTARPGIVIGKKGEDVEKLRQDLTKQMG--VPVHINIEEI---RKPELDAMLVAQCVAQQLERRVM-FRRAMKRAVQNAMRI-GAKGIKIQVCGRLGGAEIARTEWYREGRVPLHTLRAD--IDYNTYEAHTTYGVIGVKVWIFKG--EVIGGR?????????????????????????????????????????????????????HTGCLDPLATGVLPLCFGEATKFCQYLLDCDKGYFRGDILQVPPMYCALREARCVTIGRLEL--LGTYIRTLVEDIGEALGCGAYVAELRRTQAGPFALAQT--VTLPCDCGLQDWPLVLLCEHCAFYWLHGQAVRAPDVRVQDHNGRFIPLLETIAHCLTLDPAAVRWQGIGTL---------------AVTGLACACIAAAGLALA-------NLLRGQLDCCPLVRVDRRLACFNAAHHRAAVVCVLGPVTDRN-----AEALEAAVVAAGGIKVLDLTRILAGPIATRLLVAAEVTLGKRCARYGWCGPWRDRRGFDCLVQMCCGIARAGMRWRQAERPVPLPVQALDHATGYLMAAE----AIRALGERLL---TGQGCRCRLCLARTAKLLVEHGTMDEDLPLAPECADDLDPVVRQLHIPLGDVCVGKFCDGEICIIQPTCAPTNDD--L--GIIDKRRENHCEVMHIIG-DVE---GRTCILVDDMVDTAGTLCHAAKALKEHG-MATINQLVRQPRKRC------------VEKCDVPALQNC------PQRRGVCTRVYTTTPKKPNCALRKCRVRL-TNGFEVCCYIGGEG--HNLQEHCVVLIRG-------GRVKDLPGVRYHTVRGCLDTCGVKGRNQGRCKYGTKRPK-QVNMRDML-----KAGVHFGHQTRYWNPKMGK--YIFGAR--NKIHIINLEKTLPMFNDALAFVERLAQGKNKIMFVGTKRCAGKIVAEQAARCGCPYVDHRWLGGMLTNEKLDRCLGGIKDMGGLPDALFVIDVDHERIAITEANKLGIPVIGVVDTNCCPEGVDFVIPGNDDAIRAIELYMTCMAD-AV---IRGR???????????????????????????????????????????????????????????????????????????????????????????????RYIFVTGGVVCCLGKGIACACLAAILEARGLKVTMLKLDPYINVDPGTMCPFQHGEVFVTHD--------G-----AETDLDLGHYERFIRTTMTQNNNFTTGRIYEHVLRKERRGDYLGATIQVIPHITDEIKRRIDVALVEIGGTVGDIECQPFLEAIRQLRVEVGCKRAMLMHLTLVPYIATAGETKTKPTQHCVKELRCIGLQPDVLICRCDHPVDACCRRKIALFTNVEERAVICLEDVDTIYKIPGVLHAQGLLDAYKCLIEAMCHDAILVPGGFGLRGVEGKITAVQYARENKVPYLGICLGMQVAVIEFARNVMGWKDANCTEFDRNCGHPVRTEA----SDLGGTMRLGAQDCQIVAGCKVHDCY-GKDVITERHRHRYEVNNN-LLPQLMDAG-----LVVC----GRC-EDGALVEVVEC--KD--HPWFVACQFHPEFTCTPRDGHPLFAKFVECYDIAVNL-GVDPRK-SDQVVRCATVLPHGTG-KTVRVAVFTQGPAAEAALAAGADRVGMDDLAAEMKGGDL-------NYDVVIACPDAMRVVGQ-L-GQVLGPRGLMPVRYRTDKNGIIHTCVGKVGFEAGKLKENVEALIADLKRIKPACCKGIYVKRVTLCTTMG--------MARYIG-----PKCKLCRREGTDLFLKCGVRALECKCNIEAAPGIHG---QR--RGRQ-VLERQFRGYYQAAACKKGATGENLLQMLECRLDNVVYRMGFGCTRCECRQLVCHKAICVNGKTVNIPCYQVRPGDVVCVLLGPHVCEKATVLAEKKGQFVFKVATDATKLEIKKAVEGLFNVKVENVCTKKAIVCLQPGQ--D-LDFCCCAE????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????AKVLGAQRRGDGCWDVCVTWCIGHYKAVKRLLGEAR----ELVIATDADREGEMRCRADWLIGMNMCRLFTL--LGRQCGYQGVLPVGRVQTPTLRLVVDRDLGAQETLDIAQALYE------THKLIT--YPRCDCGYGEAPGILAALQRADACLAPL-QPYLDPQR-------RCRAWNDQKVCAHHGIIPTAAACD----PCRLPPKYKAVYTLI-------RARYLGKLVQRCCGMRLTITGPAA-GK-AAAPMEVPRVTKITLNMGLGEAIGDKKVIEHAVADLEKIT-GQKPVVTFARKCIAGFKVREGWPIGVKVTLRRDKMYEFL-DRLLAICLPRVRDFRGLNAKCFDGRGNYCMGVKEQIIFPEIDYDKIDALRGRVCTVPTGVMRLLDKQAGRLRLEALVLVTGPTGCGKTTCLYAALARLDAC-VC-NILTVEDPVEYDLPGIC-QIQVNARIDM------SFAVALRAI--------LRQDPDVIMIGEIRDLETAQIAVQACLTGH-LVLATLHTNDAVCAVNRLV---DMGVEPFL--LACALLGVLAQRLVRRLCPHCREPDPAT-----PGQYR-------AV-----------GCAQC-N?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????AGQLLAQVFAHLDGFIRPGVTTMQINDRAEAFIVETLKARPACKGQYGFPYALNTCVDHVVCHGMPKVGE--VLNEGCIVNVDITLEQGGYIADCCKMLVDTTYDALWKGIEQVRPGATLGDIGHAIQAHAEAAGYCVVREYCGHGIGT-QMHEAPE-VLHGMVFTIEPMIN--QGGRGTRGLRDG--VITRDHTLCAQWEHTVAVTECGYEVLT-----------------------------------------MNAAPALLAED-INHRYG-DIQALRDVAFCLPAGTRCGLIGPDGAGKCTLLGLIAGVKRLQCIRE----NIQF---FATLF---------GLGRAECR---E-RMACLLRATDLERFAERPAGKLCGGMKQKLGLCCALIHEPDLLILDEPTTGVDPLCRRRFWELVEQVRV-----QRPQLTLLVATAYMEEAEQFEHCLMGPC--QELAAVTACGKLDDAFTHFQGA------------GRFTAVNKVCFAIGRGEIFGFLGCNGCGKTTTMKVLTG--LMPACE------GF-------MCQCFCLYGELCTRQNLELHALPLGLRQRLCLAVAVLHRPEVLILDEPTCGVDPAARDGFWRLLVELCREQGVTIFLCTHFMNEALRCD
Pyrobaculum_arsenaticum_DSM                             GAQ-VVLIPCNPLCT-----QDAWRGMCDREYYNAIGFALC-----FNPTITLDDGADLTATIHGGTEETTTGVIRLRALKKAGKLLYPVIAVNECYTKYLFDNRYGTGQCTWDGVMRATNLLIAGKNVVVAGYGW-VGRGIAIRARGLGARRVIVVEPIRALEAVFDGFEVM-PMDKADIFITATGNIRAINLGHIFKMKDGAVLANAGHFNVEIDVAGLERI-AVAKRRIRPY-LEE--------YALPN-GRRVYLIGEGRLVNLVA--AEGHPCEVMDLCFANQVYKLPDEIDREVARLKLKTMGIEVEELTEEQRLYICCWDIGDLEDAKQKIRELVE-LPLRHPELFKHLGIEPPKGILLIGPPGTGKTLLAKAVANEA-----NAYFVAINGPEIMCKYYGECEARLREIFEEAKKNAP------AIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLQERG------QVVVIGATNRPDAVDPALRRPGRFDREIHIPMPDKRARREILGADIAALAKEAAMAALRGPPGVGKTLFAKA---VATECGANFIAVRGP--ELLCKWVDEIDCIAPARGCRLGDCGVTDRMVNQLLAEMDG--IGTLKNVVVMAATNRPDILDPALLRPGRFDRGIAWIYCCCNNTIITITDLTGAETVARVCGGQVVRADKDKPCPWAAMQAAYKAAQLAMARGINAVHIKVRGPGGY-GMKVPGPGACAAIRALARCGLVIGRIEDVTPIPHDIIRPPCGRKGRRGPAGRYGARYGMGIRRKITTIEVKQRGKHRCPCCRCVVRLERLAFGIWRCPKCGFTFAGGAWVPVDAGAVKRIIDGADVMRPGIKHLDGDFEKGDVVGKVLINIHYLGDYTYMAMWYRKIGR-EVHERLMRKILIEWRRAPCIVRVERPFRLERARKLGYKPKQGVVVARVRIMRGPFNRRRPDCGRRPKRMGVYGITA-WKCWRQVAEERAARKFPGLEVVNCYWVADDGVYRYFEVILIDCNQLTIRGDPLYCGICGKEVPRR---------RIMRRLVVELLHEPGLNAPVARIVTE---SGAEFFNYAAEGLYVGQVIGCGATPKAGNIMILGEIPEGTMIFNVEKRAGDGGKYARCCGTYALPCGRVIEVDARGRATVGIVAGGGRIEKPFLKAGKKYHRARAKAWKYPTVRGKAMCPYAHPHGGGCHQK-GG--TP--VPK-TAPPGQKVGFIGCRRNAGTLAHVDHGKTTTTDCLLMGAGLLCP--KVAGKALAMDFVAIEQLRQMTVKAANICLYFEYGGKP----YLVNFVDTPGHVDFTGHVTRCLRVMDGGLVVVDCVEGVMTQTETVVRQALEEYVRPVLFINKIDRLIKELRLCPQEIQQRILTIVKDFNALILTMIIEHVPPPNVAQKYRIPRLWRGDLNCEVGKAMLEADPNGPTVIAVCKVNKDPHAG-LIATGRVFCGTIREGDEVYIIGR-KMKKKVLQTYIYMGPTRIIVPYMPAGNIVALMGVDEARAGDTEKMRYIAEPVVTVAIEPKNPAELAKLVEALKDLVIEDPTLDLKIDQETGQILLCGVGTLHLEIATW-LLKERAKTEFTVCPPLIRFRETVRERC-QVWEGK------SPNKHNKLYFYVEPGIQYLREIRDYIVQGFRWAMEAGPLAQEPMRGVKVVLVDAVVHEDPAHRGPAQIMPATKNAIFAAVLCARPTLLEPLVRLDIKVAPDYIGCVTCVLNKHRGKILDMTQQEYM-AYLRAELPVLECFT-ICDELRAAAAGKIFWCMQFARWAPYPDILCNALIQIKNAEVMGKRQVTIWPVNKLTYYTLRVLQRYGYVGEIEYVD-DGK-YIVQLLGK---INDIG-------PIRPRYPVKYREIVQ---WEQ-KFLP--ARQIGILVICTCQGVVCHIEAKEKKIGGVLLAYVYGDVQVAVVGPPMCGKTALLRCLTPCLV---LDQCCDLNTVTLA-TVRNADLH-------EYGIYHALLEDILQATGRIRVFTKPVHCKWYVEKPFKY-----AIVGRDYVLCD----NDMPCVKDVPADLLIGELARYIKENVPQVKPPVWAPFVKTGANKERPPDTP-D-WWYIRAACIIRKLYLYG-PVGVGCLRTAYGYRAK--IGDKTRPERTRKAGGAVIRKILQQLEQAGFVAKTKK---GRVLTPEGRCLVDRIVDAAGHIAGRLATYIAGVR-VVVINAEKLAVTGDEKMVVEWFKKKICEWRTHYNPEKVGPKVPRRPDRVFKRIVRGMLPK-KCWTGGKVVANPQFQDTLKQLGIDPNVVIQKVQEELKRVG--KYPVQKVELEV--TCPTRYEVKVYLPPIGDLFLRLFGKDV------GAHDCRN-EVIGNLCFEQLVEIAILKKDELKCKCLKCAVKQLLCTCKAMGITVDGKRADEVLKEVDGGKAGMLHAVVVDDRPTCPLYGKEVVKAVTVLDAPPLFVWGFRL-YTLDPTNGYLRCAAEGKTVCPKDVFCPGQLVDVIAVTKGKGWQGVVKRFGVTILP-RWHKHRKGHRR-TGTIGP-QAPA-LMFTQPRPGQMGFHQRTEYNGFPHYGVIKGPYILIQGCLPGARKRLVVLRHPARGLGIHPREAADHHAYAAGPGLGPALRVGAVLARAIAIKLGVPIVPVHHGIAHIEIARYAT-----KCCDP-LVVLICGGHTVIAGYCD-RRYRI-FGETLDVAIGNAIDMFAREAGLGFP----GVPAVERCGE------SA--DRLVEFPMPIVG-----QDMCYAGLTTEAAYYMLAEVTERAGGVARCRRLREILCQV-GAYHGAEVKVVPDEYAGDNGAMIALTGYYAYKRGRIRLYGTNPADVDQVAREIVDLAKKMGVQVRGPIPLPTRRLVVTVRRAPCGQGYHTYDHWEMRICKRLIDI-EACERVLRRLMTIRV---PDTVKIELIKFGVLCPEVIRKYCVMEVTTCEVYDEGGL-PVRGGICDRRL-GVAEPGARCETCGQTHDVC---PGHFGHIELVKPVVHVGFAR----VIYDILRTTCPNCPH-------CRDRLCKIPC--EDR----PEWAILKVLPVPPPHVRPCIQLETGIRCEDDLTHKLVDIIRMNEKLKIAIETGAPTNVVDNLWDLLQYHVATYFDNELPGI------PVAKHR-GGRPLKGIAQRLKGKEGRFRGCLCGKRVNFCARTVICPDPHICINEVGVPTDIAKILTVPEKVTAWNIDVLREYVIRGPETWP-------GANYVERHLRDGDIVLFNRQPCLHRVCMMGHLVKVLPGRTFRLHLAVCPYNADFDGDEMNLHVPQTEEARAEARLLMLV-ENHIITPRYGGAII--GARQDYIIGAYLLCGKQIICHFLPDGFTCGRLEAMPGFTVEETFENKVCEGYLMAKTGARGCLVNIVQMVATLGQQTIR--------GERIRRGRTLPHFPVGDI-GAFCGGFVKHCFRCGLTPVEYFFHAAAGRDGLIDTAVRTAQCGYMQRRLINALQDCAE--VALVYRVLPDCVEVNIDKLE-EIGFGIKALRFYIRMPECEEYCCDEVEELLRCVEGVVKGPLGELVKEFRNT-PVVMNVQDGK----ITYKGILKNMFLGVTKGWRYKLKIIYTHFPVLAKVQGCQ--LVIENFLGRKCKITLDI--PKGVKVEV---KGKED-IVVEGIDRELVGTFACCIGIDEAGRGPVVGPLVLAIVDCKCLCPRAREVLYGKIEA-VPQVAAACIVAKVVRDRLVEMLRK---EVGGRIRRPLLVVE---DGGVVEYLDADEGAIACIIPFLEHNQCPRNQYEAAMAKQGLPQCN-FLYKLDCRGHMLYY-PERPVTTRGLELVG--YCKRPA--------GQNAVVAYTGYNIEDAVILNKACVERGMFRCVFYRTYETEEQRYPGGD-KIEIP--DCCVK--GYRGPEAYCHLDE-DGIAPPEVYVRFY--TTLETE--RI--LKERRDACRRGEKGIVDRVLVKVRLRELRGDKFACRHGQKGVVGMLLRQEDMPFTENPHALPCRMAQLLECMAG-------KGKEVMYCGITGEKLVADIFIGIVYYQKLHHMVADKIHARARGPVQILTRQPTEGRCREGGLRLGEMERDVLIAHGACALLYERLVECCDKYTMYVCEL--CGYAFKLLLQELIALGIYPKLDTGLYIEALGGFPGPYGEVRGTIAQVPRGTG-GFGYDPIF-VP-------EGLG-RTYAELGDDVKKTAVARAVIRPGIGRVRVNECWPI-EMARVKMQEPDIDVNVCGGGFMGQAVAVRIAIARLKELYEKYDPYMLKGDPRRTEPKK--PGIKHARCKRQKAYRTKNLTPGKRVYGEREWNPYRCKLLYLGAACGTTPCHICDIVGEKGLIYCVEFCPRVAQPAQAKILADNGYVM--LVIKA-----MCIDVTAPATETFKQ-EINTLVFYNPAMEKN--RTDICREAVELIKKNDIDPFGCPAPFLQAGFRA-LREEGVICVTATDTAVLVGRYPKKCLRRYGAVMF-KTPFYIEAGLRNLTGYVARVAACEDYGFE--PLFAYWEGHYFRLCARAVRGARDADCNFN-FIGLAGPPGVGKTTLIHALALRRICTCE-------GAKCEEEALRCIAKCCLGDLRAAINDLDPGLRRYICLRPVVLPHTEGRYQKKRFGKARIPIVERLINLMMGKKHKAYNIVKRAFDLVYYKTGKNPLQVFIDAIINTAPREEVTRIIMGGIAYAVCVDVCPQRRLDLALRWIAEGARACC-FNNPKPIEECLADELVAAAAND-PK-SYAVRKREELERIAAACRRG-SRTHGWGRVGQHRKCGGCGGKGMVGF---HKHKWC-LVMKYGECGTGWPFYG--KHGFKLLGGGCIDVPVIVYTPVACKTAVEKIQRAGGGKTLEELL------NMPMDEFIKLLPARQRRCLKR----GIKTHCRDMIILPEMVGLTIQVYNGITYIPVYICPWHIGHYLGEFALTTKIVQHGEPGLKATRCCLHIAAKADNCGAKLVRVIGVVGHYCKTVHRRIPGAGVGDMVVVVVKEGKPE---LRRQIFRGIVVRQRRPYRRPDGTWVAFEDNAVVIVTPE-GD-PKGCEIHGPVAMEATLR-WPTIANLARLAAEILGVGVCRIKI--SPEAQDKIEDVVTKDDVRCLIDQGLIWAEPEKGVCRGRWRVRHQKKK-AGRRRGPGCRKGKRTDEG----EVWKNKVRAMRRFLNTLKRRGK-LDPKTWRQLYAMVKGNYFRDLGHLWEPRTELGRMVKEGKIRTIDEVFANNYIIKEPEIVDILV-PGLGERCLFQAVVAVGNEDGYVGVGIGKARQVRQAIEKAVREAKLNLIPVRRGCGCWKCCCDEPHCVPFVVKGKCGCVEVTLIPAPKGVGLVAGDVAKAVLRLAGVKDVWTHTRG-----DTRTTLNFALAVYNALEFLEYRLCKYGYIDCEILKT-PLGTRIVIYAERPCRIIGRKGAIVKEVCNILATKLG-VENPQIDVIDVCKIEAPEMFPKVVAYRIANAMAKGVR-FRRVMFAAIRQLTEA-GAKGFEIVVCGKLCT-ERARFEKQTFGKLYKIGYDAKNRVRRAVVHVLLKPGIYGIEVRIAPA--SLQYCDLKRILTPEALARLDNIRIVRPELAEALEQQIIALACCGRVKVPIDDNTLKKILHAGTLDPKVCGVLPIAVAEGTKVLMALCRCDKVYFQGEIYQKPPLRCAVRQLRTRRVFCLEL--LGTYARKIIHDIGEVLGVGANMRELRRVAVTCFTEDEA--VTLPIEEIARHLPKIWVRDCAVDAVCHGAPLAAPGVAMFTLKGELVPTVTRPTRRLPLCKRL-FWTAVVATVYILMTITPLYGG--TLAHLGIGPIVIAGILLEVFAFC--GILNLDLNK-REDRLKFTLLLKQLLL-ATIIIMLLDDLMCKG-----IGCAICLIIFLGVTILLLYVLLYLEMMKVNIPPLRFVYVCVLPIIFAWV--WVQLAGLCA-EDQAKQFAQCQLHIPGFRQCEKIFAKILERPINALTIICGFIAGCFAALGNIL---GVWG-------SGAGLILLVEIGLQYYALVMREQIMEMYPLLEVGVVKFGD---FVLCCGLKCYIDLRAVLGHPP--F--GYVRPEAKGAGRQ--IEG-AEV--AGKRAVVVDDVLTTGKCVLGAICAVGEAGGLFAGGKLKRKRKRFKWNDVTYKRKML-GLVEKYDPLEGA------PMARGIVLEKVGVEARKPNAAVRKVRVQLVKNGKVVTAFVPLDGCLNYINEHDEVVIERIGGPEG-RCLGDIPGVRFKVIK--VNGVCLWAIWCGK----KQKPTRLVPLEKYL-----SAGVRLGTRLC--NKYLEDRGFIFAVRP-DGLRIFDIKKIDERLKIAARFIARY--PPDRVLVHTTRPYGFKPVQMFCKYVGCKALTGRFIPGTLTNPNLPHYQE--------ADLLFVVDPKLDAQAVAEAAKMGVPVIALVDTDTPHQYIDFMIPCNNKGRKCLALIFWILAR-QV---LRER-MTIAVRKDLEICCGKAAAQVGHAWLTEGQKKVVLAAEDAAHLYQIYETAKRLDLPTAVVVDAGLTELPPNTPTAVCVGPGPDDVVDKVTGCLRL---------MCCVGKGVVVACIGRILRARGLCVNAVKIDPYINVDAGTMNPYAHGEVFVTYD--------G-----GETDLDLGHYERFLDVELCRRNNITCGQVYLCVIEKERRGEYLGQTVQLIPHVTDEIKRRVDVTLVEIGGTVGDYEQLPFLEAARQLGLELG-EDVVFIHVAWVPLLKITGEFKTKPLQHCVAELRRYGIQPDAIVVRCEKPLDAPCVKKIALFANVPQWAIFNCYDVDTIYRVPLILEQQGLPDAYLCIVEAVRHDAMIVLPGFGKRGTEGMIECVRHARVHKIPFLGICFGMQLAVVEFARNVLGLKGANCTELDPETPYPVQREV----DVMGGCMILGNREIEIVPGTLACCLY-GTCVIAERHRHRYEVNLC-YLPKLAEAG-----LVVC----GWR-RDVKRVEIIEL--PC--HCYFIATQFHPEFKCRPTKPRPVFRRFRQCVELIVVLRELDLCK-PENRINLLVELPHPP--KANKIAAFAHGVFEVNAKNAGVDAIITRDQIECLCGNKRAIRKLAKQYDFFIAPPDLMPLLGRVV-GPIFGPRGKMPVRVRIRNEPVIKVRVGAEGQDQKEILANILTVLEEINRKFCLKQ---YLKEIYVKKTMGMGGLRKP-KKKYLAGKPKKIWNKQLLLEELQLMGEYGLR---NKRELWLARARLKWI-TR--RARCLLYKAGFI--EDPNVPLDRILCLDVRAILERRLQTIVYRMGLAKCIYHARQLIVHGHIAIEGRRVTCPGFLVPRELEDKIVRRILITEKTLRLAEKENKITIIVDRTATKKQIADEVARLYNVKVDKVNTKKAYVKLAEGY--NAMDLLCRLGVYGPDGAYIAEIDA-PPHFFEPVRPDLIRRAYLCALCARFQPKGVYEGAGKEHCC------ECFGV--GLGIARIP-R--YKGCLWP---R-GCFCPNTRGGRRAHPPRVEKKLHEEINKKEKNLAIRCAIAATAYRTWVATRGHVIDKVQCL--PVVVCGDAEK-IAKAKEARKLFEALGLWPDVERAAEGT-KIRAGKGKMRGRRYKEPKCVLVVNFPGVDVVPAEHLNMLVLAPGAVPGRLTLWTAPAAKLDKGGEHFEILIDPDAALEFK--MGK-P-MGIDKILIHEEIFKDAKKGLRACEQALKRIFGTTDVRKIAEIIIKEGEIPLTAEQRRRLIEDKKRQIVEWICRNCIDVR-TKTPVPPQRVENALDQVRVCIDPFKPPEEQVQEILKEIQRVLPIKVATARIALCVCCTHAQKVKGIVAKMA--KIVNERYKCDGCWEAVL-ELPAGLQDVLICKVNDVTHGVCKIENGTVIDHIPAGRA--------LAVLRVLGITG-KEGAR--VALVMNVECKKLG-R-KDIVKIEGRELTPEEVNIICAVAPTATINIIRNFEVVRKFNVTPPEVIRGR--FKCKNPTCITNAPR-EPVEPTFYLV-RRE-PPLFVCAYCTNWQLRMLARFLRKAAKCNCCNIWRVVAEFVEKPRRQRV--VVNVGKLNRIAEEG-----DVVIVPGKLLGGGQLKKK-LVVAAVGACPKAIQKVLEAGGEV--LTIPELVR--RNPKGCGVKIPVRCFTCGKPLGHLYAVFKQRV--LAGE---HP-----GKVLDDLGLVRYCCRRTLMAHLKEGCYVVI------DGEPCRVVEIEKCKTGKHGCAKARIVAVGMFDGGKRTLCLPVDAQIEVPIIEKFTAQIQLMDMRDYKTGCEVEVWQI-LDRYKIKYMIVAQIEVNGCVDI-----IGAFCQTEGLLGKDM----DLRELQMMGRIGRIA---ALVECIER--------VGPYPACVKVIEIRDLREEKRKKIIEKAVDKCDAIIIVEGRAD------VVNLVK--HGYRNVIAGICRGVPQTIIDLCKKKNV--TVFIDGD--------KGGEL------VLKELLKV-AHVD---YIARAPPGK-EVEQLTAKE----IAKALDLAAKK--GVKVIITARTG-PL-TKVPMQRIFIEKVVVNIGVGTG---GERLEKAAELLKELT-GAEPCRRRAKRCIKDFGIRKGEPIGVMVTLRRDQAVNFL-MRALQ--AV---NNR-VKRTCFDDRGNVCFGIKEHILLPGVKYDPAVGIWGRVVVVFPPEITATKP-VVRKKIEDYILVAGAPGAGKTTFAQALAEFYLCK-GK-IVKTIECPRDMVLPP---AITQICKNLA------TCEEIHDLL--------LLCRPDYTIFDEMRDTADFQLYVDLRLAGV-GMVGIVHATCPIDAIQRFIRRVELGMIPCI---IDTVIFMKDGEVRKVYALCMVVKVPAGMRE--EDLAR-------PV-ILVKDF--ITDEVEY-EGGDLKKPCGG-KKRKVRRTKKKALGGGPPQIPKLG--EED-VRIVERVRGGNIKVRLREAKYANVYIPKEKRYVKAKILCIVETPANPDFARRNYMVKGAVIRTEVGKAVITCQPGQDGIINAILVGDVVHKALKYALDLAQPDTPVLELCEKVEALIR-ANDAKPA------FP--VNVCINNVAAHYTAKRGDALTIPKCGVVKIDVGAQREGYIVDAAVTLQKAARCALECALAAAKPGVKAWQIGEAIEKAIKCYGFTPIFNLTGHKIERYLLHAGCV-IPNGDVYAIEPFVT--NGEGYVVDGREITILVEKCGGFVAQFEDTIYVGENEVVPLACQ-PKKCG-HECVKYCPICEALCIG--CGICVHKCPFEAITIVNLPDELERD-CVHRYGPCGFKLYRLPI-LKRGKIVGVLGRNALGKTTMARILAGELVPNKIQ-----YIEL---IPLYL--KGT-VGDIIKKA------G-IRDELVKRFGLDKLVCREINKLCGGELQKLAIAAALCKDADVYIFDEPATHLDVVERVKVGDAIREYTQ-----NKYVLVVEHDLTVLDFLADNVVIVYGKP--GAYGIVCHPGGAREAVNEYLCG----YICCENMRIRFQLEVCACY-IAKGEVVGVVGPNGIGKTTFLKVLVG--EVKPQC------GY-------KPQYIRDIAVKNQDVPVCLWLLCGGELQRVVVAACLLKKADIYVLDEPMAYLDVEQRITVARTIRRIIEECEVAALVVEH--------D
Pyrococcus_abyssi_GE5                                   GAK-VCAAACNPLCT-----QDAIRGECKEEYYEFMNKALD-----IRPNIIIDDGADMVCLVHGACEETTTGVIRLRAMERDKVLRFPVIAVNDCYMKYLFDNRYGTGQCTWDGIMRATNLLVAGKNVVVVGYGW-CGRGIAMRARGLGAT-VIVVEPIKALEARMDGFLVM-SMKEADIFVTATGNIKCIRREHFELMKDGAIMANAGHFDVEIWKPDLEEL-AVEICNPRPN-VTE--------YKLKD-GRRLYLLADGRLVNLVA--ADGHPAEIMDMCFALQVYVLPREIDEMVARIKLQCMGINIEELTEEQKKYLECWDIGGLKEAIEKIREMVE-LPLKHPELFERLGIEPPKGVLLYGPPGTGKTLLAKAVANEA-----NAYFIAINGPEIMCKYYGECEERLREIFKEAEENAP------AIIFIDEIDAIAPKREEVVGEVEKRVVCQLLTLMDGLKCRG------KVIVIAATNRPDALDPALRRPGRFDREIEVGVPDKQGRKEILGADLAALAREAAMVVLRGPPGTGKTLLAKA---VATECQANFIAIRGP--EVLCKWVDEIDAIAPARGTAEGE-KVTDRIINQLLTEMDG--LVENCGVVVIAATNRPDILDPALLRPGRFDRGIAHIYCCYNNTIIHITDITGAETICRWCGGMVVKADRDEPCPYAAMLAARRAAEEALEKGIVGVHIRVRAPGGC-KCKTPGPGAQAAIRALARAGLKIGRVEDVTPIPHDGTRPKGGRRGRRGCAGRFGPRYGLKIRRRVAAVEAKMRQKHVCPVCGR-RAVRRICTGIWQCKKCGAIFAGGAYLPVDEGAVPHILNGADVMAPGIVDADENIKEGDFVGKAVKVIHHARDYKYIREAWKCPKK-SYVGQLLKQRMIKWRREPAVVRIERPTRLDRARALGYQAKQGYVIVRVRVRRGGRKRPRWKGGRKPCKMGQVKYCP-KKCLQWIAEEKAARKFPNLEVLNCYWVGEDGMYKWFEVIMVDPHHPVIKCDPKIAWIALKHHKGRVFRGLTCAGKKGRGLVEEIMHDPGRTAPVARVRFE---NGMEKLIIAPEGLLVGQEIGPDAPIAIGNTLPLAKIPEGTYVYNIEGIPGDGGKYVRAGGTYALPCGELKAFNPNCRATIGVVAGGGRLEKPLVKAGKAYYKYKARNRFWPTPRGVKMNAVNHPFGGKEH-H-PG--KPTTTCR-RAPPGRKVGHIAARRNIGIAAHIDHGKTTLCDNLLAGAGMICE--ELAGKQLVLDFDEQEQARGITINAANVCMVHNYEGKD----YLINLIDTPGHVDFGGDVTRAMRAIDGVIIVVDAVEGVMPQTETVVRQALREYVKPVLFINKVDRLIRELKLTPQQMMERFCKIIMDVNRLILDMVVKHLPNPIEAQKYRIPHLWQGDINCDVGQAMLNCDPKGKMVMVVTKIIIDKHAG-EVATGRVWCGTVKCGQEVYLINT-KRKARIQQVGIYMGPERINMEAVPAGNIVAVTGLRDAMAGETEALHYVCEPVVTVAIEAKNVKDLPRLIEALRQLAKEDPTLHVKIDEETGQHLLCGMGELHLEVKLY-KLKKDWGIDIDVCEPIVVYRECITKPC-PMVEGK------SPNRHNRFYIVVEPGVQYLNEVMDLLIDGFHQAMDEGPLAKEPVMKVIVRLIDAQVHEDNVHRGPAQIYPAIRTAIHCAMMKCNPVLYEPYQKVIINIPYEYMGAVCREITQRRGQLVDMKQEGEV-MTIIAEAPVAEMFG-FAGAIRCATCGRALWCTEHAGFKRVPDPLANALCHITNCERVGKREVYIKPACKLIGEVLRVMQKYGYIGEFEFID-DGV-YRVQLLGK---INKAG-------AIKPRFPVKARDYER---WEK-RFLP--AFEFGILIVCTCQGVMCHKEAREKGIGGRLIAYVYGAAQIVLVGLPNVGKCELLRALTPGLI-EGAALGKGMGPQLLA-VIRNADLR-------EEKIHCAVKEALYDVAEIIRVFTKCPGEEPA-YPPFRY-----ARVGPDHVLED----GDMATVYDVPGDLLVERVAQRLK-EIPEIKPPEWAPFVKTGRHKERLPEQE-D-WWYYRVACILRRVYLDG-PVGIERLRTYYGGRKN--RG--HAPERFYKAGGCIIRKALQQLEAAGFVEKVPG--KGRVITPKGRCFLDKIANAEGLILGRLACRVAGEE-VVIVNAEKAVITGNREVIFCKYK-QRTGLRTLTNP-RRGPFYPKRCDEIVRRTIRGMLPW-KTDRGGKATPGPPLGPAIGPLGLNVKQVVDKINEATKEFA--GMQVP-VKIIV-DPVTKQFEIEVGVPPTCQLIKKELGLEK------GCGEPKH-NIVGNLTMEQVIKIAKMKRNQMLALTLKAAAKEVIGTALCMGVTVEGKDPREVQREIDEGKAGMTHILMIDDEPG-LTNGKEIFMPVTIIETPPLRVFGIRA-YRQGYLG--LETATEGKELRVGEVLKEGELLDVIAVTKGKGTQGPVKRWGIKL---RAHKDCKGRRK-VGCIGP-WHPARVMWTVPMAGQMGFHHRTELNGFPHYGIVRCDFMMIAGCVPGAIKRIIRVRPAIRG-GIHPKEAAEHHAFCQGPGLGPALRVVATAARALAVKYRKPIVGVNHCIAHVEITKMF------GVKDP-VGLYVCGGNTQVLALEG-GRYRV-FGETLDIGIGNAIDVFARELGLGFP----GGPKVEKLAE------KG--EKYIELPYAVKG-----MDLCFCGLLTETAFAALVEVTERAGGVAANNRLREMLRIM-TEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKAGRIKLACTNVRCLEEVANQIKQIAERTGVRMCGPIPLPTKRIRIVTRKCPDGEGCATFDRWELRIHKRLIDI-EADERAMRQIMRIRV---PEDVTIEIIEFGILCPQEIRKMCAVEVTVPDTYDDDGY-PIEGGVMDKRM-GVIDPGLRCETCGAKAGEC---PGHFGHIELARPVIHVGFAK----TIHRILECTCRECPH-------CRDRLEKIPD--KDR----PEWMVLTVLPVPPVTARPCITLETGIRAEDDLTHKLVDIIRINNRLKQNIEAGAPQLIIEDLWDLLQYHVTTYINNETCGV------PPAKHK-SGRPLKTLAQRLKGKEGRFRGNLCGKRVNFCARTVICPDPMICINEVGVPIQIAMELTVPEKVTEFNIEKLRKMVLNGPDKYP-------GANYVERHLLDGDIVLFNRQPCLHRMCIMAHRVRVMPYRTFRLNLAVCPYNADFDGDEMNLHVPQTEEAQAEARILMEV-QNHIICPRYGGPII--GGIQDHICGGYLLTGKTIFCLLLPDGYKRGELEPLPGKTLEETLECKINHTVIMAKTGARGKILNITQMAALLGQQCIR--------GKRLYRGRVLCHFKPGDL-GARAKGFVVNCYKCGLCPQEYFFHAMGGREGLVDTAVRTAQCGYMQRRLINALQDMCDFNIVGVIKVMPCDPEVNLDELE-PIAFGLVALKFYVLGKDEEGYCFDEVAEKFKEVENVVKGPKGEVERELFWP-GVKIFVEGGK----VTFKAHINNMIKGVTEGFTYKLKVVYCHFPITVKVQGDE--VIIENFLGEKAPRRAKIL-P-GVTVKV---KG-QE-IIVEGIDKEAVGQTAANIGADEAGRGPVIGPLVIVAADCKQLTPAQREKLFDEIDAKYEIVCAACILAKVIRDREIEKLKA---EYGGRVRRPLIIVE---NGGVIEYLDAEEGLPACLIPYPEHNAAPRNTYGAGMAKQGLGWAN-FRIRVDTRGHLLHY-PQIPVNCRIMKAVG--YEDRPA--------GQNFVVAYHGYNMEDAIIINKACIERGLARCTFFRTYEAEEKKYLGGD-KFEIP--SPTVR--GYRGEKYYRHLDE-DGLIFPECKVRFL--EER-GLGAVC--LQERRETCRPCERGVVDKVLVKVTVRDLRGDKFACRHGQKGVIGLIVPQEDMPWTENPHGIPCRMGQLLEAIGG-------KGREIMYDGITGKRFEADIFVGVIYYQRLHHMVADKIHARCRGPVQVLTKQPTEGRAREGGLRFGEMERDVLVGHGAAMLLIERLLEECDKTEVWVCEN--CGYAFKLLLDELKAMVIRPKLDCGLFIECLNGFPGVYGVTWGRIANEKRGEG-GFGYDPIF-IP-------EGCE-KTFAEMTTEEKKTAIARAVIREGKGRVRINELVEP-EIARFTILEPDIDVKVQGGGFMGQAEAARIAIARLKEKFIKYDRTMLVGDPRRTEPHKPNRCTKGPRAKRQKCYRTKNLVPGQRVYGERIWNPHRCKLLYLGIACGTTACHVCDVIGWEGKIFGIEFCPRVAQPTQAKILIDNGYGM--IAVKC-----RCIDVTKEPEQVFRE-VEKELVFYNPRMALN--RDDICEDAYNLMKKNDLDPFGCPMEFLDTALRC-VKRKGILGITATDGAPLCGAHPKACMRKYLAVPL-RGELCHEVGTRILVGVVARYAAKYDLGIE--VILAYYKDHYFRAFIKLKDGARKGDECLE-NLGLAGPPGCGKTTTVYALALVRILKRE-------GITVPKEVLVEIAKRACGDLRAAINDLDPCLKPYINLEPRLLPHTHGRHAKKHFGKANVHIVERLINKIMCKKVKAYEVVKEAFKIIEKRTGKNPIQVLVWAIENAAPREDTTCVMFGGIRYHVAVDICPMRRLDVALRNIALGACAKC-YRTKMCFAEALAEEIILAANKD-PK-SYAYCKKLEIERIAECCRRG-SHTHGWGCKKKHRGGGCKGGRGMAGTGKRNKCKWT-WTIKYAPD-----HLG--KRGFKVLGTGKITKPLVIKARAFCCKAEEKIKAAGGGYTLEQLM------NMCLEELAKLLPARQRRCLKR----GIRTHCRDMIVLPEMVGLTIYVHNGKEFVPVEIKPEMIGHYLGEFAPTRKRVQHGAPGIGATRCCMFVAVKADNCGAKVIQVIGVVE-Y-HGTRRRLACAGVGDMVVATVKKGRPD---MRHQVVRAVIIRQRKEYRRLDGMRIKFEDNAAVIVTPE-GV-PRGTEIRGPVAREAAER-WVRIGCIARVAAELLKCGENRIWI--DPERVDDVACAITREDIRRLIKEGVIKKKPVKGQCRYRARIRHEQKK-KGRHRGPGCRKGKKTARM-GKKELWIKTIRALRKELRKLKEQKK-IDRRTYRMLYIRAKGGQFKCKHQLWQPKTKLGMLVKEGQITDIHEIFRKGYQIKEPEIIDVLL-PEVGRRVRFRVLAAVGNRDGYVGLGIGHGREVGIAIRKAINYAKLNIIEIKRGCGCWECRCRRPHCVPFTVEGKEGCVRVKLIPGPRGLGLVIGDVGKKILRLAGIQDVWCQTLG-----ETRTTVNFAKAVFNALEFLEKELRRAGYGGLDIKKT-PLGTKVIIFAANPGYVIGRGGRRIRELTRILERQFG-LENPQIDVQEI---KNPYLNAKVQAVRIAQALERGIH-FRRAAYAAMRAIMCN-GARGVEIRICGKLTG-ERAKCVRFYQGYLAKVGNPAETLVCKGYAQALLKLGVIGVKVAIMPP--DARLPDLRKILTPEARERLARVRLVRPELARQVELILVQLYQAGQITERIDDAKLKKILHGGTLDPKVCGVLPVALERATRVVQALLPAGKEYFEGEIIQRPPLRCAVRRLRTRKVYYIEI--LGTYIRCLIHHIGLALGVGAHMAELRRTRCGPFKEDETL-VTLPMEKAVEHLPKIWIKDCAVAAVAHGANLTVPGVAIMTLKDELVPEVERPKKHVPLKEKF-MWTGLALILYYVLAEIPVYGG--SILTLGIGPIVTAGIILQLLVGC--EIIKLDLAN-PEDRRFYQALQRQLAF-GGIILIVLDELVCKG-----IGCGICLFIAAGVTIIVFLVVVYFECMRVEIPPIRFLYVCNIPIIFGFL--WVELTGLDA-RTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGCLTVALIAVLADFL---GALG-------TGTGILLTVGILYRFYEEIAREQICEMFPIIDCGCIKFGH---FILTCGKECYIDIKCLITNPP--L--LIIRKKKKGTGKL--IEG-EIC--PGDRVLLVEDVTTTGGCVIRAAKILKEHGGEFAGRKLKLKRKKFRWCDIRYKRRVL-RLKEKCDPLEGA------PQARGIVLEKIAVEAKQPNCGMRKVRVQLIKNGKVVTAFCPGDGAIKFIDEHDEVIIEGIGGPKG-GCMGDIPGIRYKVVK--VNRVCLKELVKGR----KEKPRRLVPLDQYL-----AAGVHIGTQQK--TKDMKK--FIYRVRQ-DGLYVLDVRKTDERLKVAGKFLARF--DPQCILAVCVRLYGQKPVKKFGEVTGARAIPGRFLPGTMTNPAVKNFFE--------PDVIIITDPRADHQAMKEAIEIGIPIVALVDTENLLCYVDLAIPTNNKGRKALALIYWILAR-EI---LYNRKQVIVVRKDLKLCKGKLAVQVAHGWFHEGQKKVVVKVECLDELFKLKAEAEKLNLPTALIQDAGLTEIPPGTITVLAIGPGPCEIIDKVTGHLKLKFIFVTGGVVCGLGKGITCACIGLLMKARGYKTTNIKIDPYINYDAGTMNPYQHGEVFVLDD--------G-----GEVDLDLGNYERFLDTCLTFDHNITTGKVYCTVIEKERRGEYLGATVQVIPHITDEIKRRIDIVVVEIGGTVGDIECMPFLEAARQMQLEEGRENVAFVHVTYVPKLRVVGEQKTKPTQHCVKELRCLGIQPDAIVARCEDPLEEGARKKICLFTNVPEEAVICAYDVEDTYEVPLLLEREGLTDCYLCIKEALKHDGIIVPGGFGARGAEGKIMTIRYARENDIPFLGICFGFQLTVVEFARNVLGMKGAHCTEIDPQTPYPVQRNL----DKLGGTMRLGAYPVKIKKGTLAYELY-KKDLVYERHRHRWEVNPD-YIEAFEKAG-----LVFC----GIAGDDERRMEILEL--PD--KRYFIATQFHPEFKCRPMKPAPVFRNFTQCVEVAVNLKDIDLKR-PENRFKLEVVLPHGRG-KDVKIAVIADGAVAEAARRLGLD-VICCAELEEIAQCPRQARKLAKKYDFFIAEAPLMPKIGRYL-GKYLGPRNKMPVRIQLKNNPVVHAPVGTEKMCDEEIAENIETVLNAIIGKLERGEC--QIKCVYVKTTMGMGDPKRQ-RKKYET--PPHPWIKERLDRERVLMDKYELK---NKKELWKHETQLKNF-RR--RARRLLKRLGLL---PEDAVLDDVLCLTIEDILERRLQTIVYKKGLARTMRQARQLIVHGHIEVNGQIIRCPCYLVLKEEEDTIIIRPVITDKAICLIEKENKLTFIVDRRATKQDIKRAIEEIFNVKVEKVNTKKAYVKLKPEY--SACEIAARLGVFDLNGQPVDEIEL-PKVFFTPFRPDLIRRAVIACWTHRIQPQGRDPMAGKRRVT------ENIGK--GHGMARVE-R--LKTPP-----RYAAFVPFARGGRRTHPPKVEKIIWEGINKKERRLAIMCAIAATANYDIVKARGHIIDNVPQL--PLIVVDDLQK-VCKTRETREIFKKLGIWDDIERAKEKT-GIRAGKGKMRGRRYKKAKGPLIVNHPGVDVVVVDNLGVEHLAPGTHPGRLTVWTVCAARLKVHGETFEILVDPYLARDFK--EGK-E-VPIEEILATPYVFKDAHKGDKACEKEMEKIFGTCDPYEVAKIILRKGEVQLTAQQRREMLEEKKRQIATIIHRHAVDPR-TGYPHPVDRILRAMEEVGVRVDIFKDAEAQVQDVIKAIRRILPLRIEMKVIAVKIPCEYVGRAYGEVRKFG--RIKKEEWACDGCWLFLI-EIPGGVEEEFYEKLNALTKGVCAIKEGTVIDHIPAGKG--------LKVIEILKLGKLTNGGA--VLLAMNVPCKKLG-R-KDIVKVEGRFLCEEEVNKIALVAPNATVNIIRDYKVVEKFKVEVPDVIEGI--LRCGNPNCITN--H-EYVTTKFYVI-SRE-PLKVRCHYCTDPNLRRLIRYLRKKCNEEKVKIWKDIAWRLERPRRQRA--EVNVCRINRYAKDG-----DMIVVPGCVLGAGKIEKK-VIVAAWKFCETARRKIEEAGGEA--ITIEELIK--RNPKGCGVIIPVRCFTCGKVIGDKYYEFKRRV--EAGE---DP-----EKVLDDLGLERYCCRRMLLCHLKPGRYIII------DDEPCRIVNITVCCPGKHGCAKARIEAVGIFDGKVRCIVKPTCAEVDVPIIDKKTAQVQIMDMETYEMGINVEYWET-LGRVKIKYIIYAEFEANGVVDV-----VGAFGQTEGLLGDDL----DLRELQKTGRIGRIA---AALETIDR--------VGPCEAKIRVVKIEDVRACKRKYIIERAVPFCDCIIVVEGRAD------VLNLLR--HGIKNAIAGTC--IPETIIKLCKERIV--TAFTDGD--------RGGEL------ILKELLQV-ADID---YVARAPEGK-EVEELTKKE----IIKALDVVCEK--GVRYLIGAKKA-NV-VRRPMRKPRIEKVTINIGVGEC---GERLTKAEIMLERLT-GQKPIRRKAKKTNRDFGIRRGEPIAVKVTLRGPKAYEML-KRLLA--AV---DNR-LKACCFDEHGNVCFGIDEHINIPGVEYDPEIGIFGRIVIAKPPEITAVRP-IKKLCIEDYILVAGPPGAGKTTFVQALAEWYACM-GK-IVKTMEKPRDLQVCE---EITQYTALNG------SMEKTGDVL--------LLVRPDYTIFDEMRKTCDFLIYTDLRLAGV-GMVGVVHATKPIDAIQRFIGRVELGMIPQI---VDTVIFIKGGKVAKVLTLEYKVKVPTGMKE--EDLAR-------PV-IEVRDF--ETGQLEY-EGRCLRKPCGG-RIVLARK-KRKRELGREPCNTRVA--EQD-KRKIIRTYGGNKKVRLTAAAYANVFD-KCGKGRKVRIIRVIENPANRQFARRNIITKGAIIETEIGKAKVTCRPGQDGVVNAILAGKIAKKVREEAVKLAKPGVCLLELAEKIEGRII-ELGAKPA------FP--VNLCLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTLMEAAREALECAICVARAGVEIKELGRAIEDEIRKRGFNPIVNLCGHKIERYKLHAGIC-IPNGDVFAIEPFAT--TGAGQVIEVPPTLILREIRNGLVTQFEHTIIVEKDCVIVTTCN-PDKCGHFLCERVCPIQEACCTG--CGICVHKCPFNAICIVNLPEQLDED-CVHRYGVNAFVLYRLPI-VKDGMVVGIVGPNGTGKTTAVKILAGQLIPNKPQ-----YVDL---LPKAV--KGK-VRELLKKVDEV---G-KFEEVVKELELENVLDRELHQLCGGELQRVAIAAALLRKAHFYFFDEPCCYLDIRQRLKVARVIRRLAN-E---GKAVLVVEHDLAVLDYLCDVIHVVYGEP--GVYGIFCKPKGTRNGINEFLQG----YLKDENVRFRFKLEVEPGE-IRKGEVIGIVGPNGIGKTTFVKMLAG--VEEPTE------GY-------KPQYI-KAE---YEGTVYELLLCGGELQRVAIAATLLRDADIYLLDEPCAYLDVEQRLAVCRAIRHLMEKNEKTALVVEH--------D
Staphylothermus_marinus_F1                              GAEDVVLAACNPLCT-----QDAWRGMCCEEYYWCINQVVK-----SDPDIVLDDGGDLHATIHGGTEETTTGVIRLKALERDGLLKYPVIAVNNAYTKYLFDNRYGTGQCTFDGILRATNILVAGKVVVVAGYGW-VGRGIAMRARGLGARRVIITEPIRALEAVFDGFEVM-PMIKADIFITATGNKAVIRKEHIEKMKDGAILANAGHFNVEIWIPDLECL-SMNKRVIRPN-VTE--------YKLRD-GRRIYLLAKGRLVNLVA--AEGHPCEVMDMCFANQVFNPPLELDRRVARLKLECMNIEIDKLTKEQEEYLKCWDIGDLEEAKQKIREIVE-LPLKHPELFKHLGIEPPKGILLYGPPGTGKTLLAKALANEI-----GAYFTAINGPEIMCKFYGECEQRLREIFEEAERNAP------AIIFIDEIDCIAPKREEVTGEVEKRVVAQLLALMDGLKERG------KVIVIGATNRPDALDPALRRPGRFDREIEIPPPDKRARREILGADLAALVKEAAMAALRGPPGTGKTLLAKA---VATECGANFIAVRGP--EILCKWVDEIDCIAPARGYRHDTCGVTDRIVNQLLTELDG--IEPLRKVVVIAATNRPDILDPALLRPGRFDRGVAHIYCCLNNTIIHITDLTGAETVCRWCGGMVVKADREKPCPYAAMIAACRAAAEAMDKGITALHIKVRAPGGH-GPKTPGPGAQAAIRALARAGFIIGRIEDVTPIPHDTTRRPGGRRGRRGIAGRYGARYGCTLRKKVRDILEKRYAPHTCPFCGAKGTVKRLCTGIWYCRKCGNKWAGGAYVPVDMGAVKPLLRGADLMAPGIREIIGVFGKGDVVGRVVENIHRIGDYHYIAQLWKRPYE-GDMLTLMRQRLIKWRREPAIIRIEKPTRLDRARALGYKAKQGFIIVRVRVRKGGLRKQRPNKGRRPKRMGIYGFAP-SKCLRLIAEERAARKYPNLEVLNCYYVGEDGNYKWYEVILVDPHHPAICNDPDIKWICEKQHRRRVFRGLTCAGKKMRGLIIDLLHDPGRWVPLAKIVLE---DGTTFLTPAVEGMYVGQIIGPDAHICNGNILPIGKIPEGTQIANIEKRPGDGGKFVRCCGTYALPCGKIIEVPNNARATIGVIAGGGRDEKPLLKAGNAYHKWKVKAKKWPKVRGVAMNAVCHPHGGGCHQH-VG--KPCTVAR-ETPPGRKVGHIAARRNIGITAHVDHGKTTLCDCLLAAAGIICE--KIAGEALALDYLDVEQRRGITVKCANICLYHEYKGKP----YVINLIDTPGHVDFCAKTTRAMRVIDGAILVVDAVEGVMTQTEMYLRAALEERVRPVLFINKVDRLIKELRLCPQEIQQRFVQIIKEVNQLILDMVVKFIPNPREAQKYRLPKIWHGDLNCEIGKAMLETDPNGPLVMLVNDVRIDPHAG-LVATGRVFCGTLRAGEEVWLVNA-RMKQKVLQVCLYMGPYRELADEIVAGNIAAVLGLDKARAGETEKLRMICEPVVTVAIEPKNPRDLPKLIDALHKLCIEDPCLVVRINEETGEYLLCGMGPLHIEIALT-FLKENYGLDVIACQPIIVYRECIRDKC-RVFEGK------SPNKHNKLYICVEPGVQHLREVKDTIIQGFRLAMREGPLAMEPVRGVKVILHDAIIHEDPAHRGPGQIYPAVRNAIYAGMLTAKPTLLEPIQKLDIKAPMEYLGNITTIITKKRGKILQVLQQGAV-ARIIAEIPVAETFD-LAEQLRGATAGKAIWGQEFCRWAPVPDTLANALATIQNAEMRAKCEALIWPACKLIINVLRVMQREGYIGEFEYID-DGK-IKVQLLGR---INKTG-------VIKPRFPVKLRDLERMPHWLR-KYLP--AYNIGILILCTPHGVLCHKEAIAKKTGGVLLAYVYGAAQIVVIGLPNCGKCTLVKQLTPPLR----PGGGPWNNRVIG-LVRNCDME-------SYRVYNALGEILFKLLGIIRVYTKQPNGPIA-DKPFKY-----AKIGLDHIVMD----GDMVTALEVPADKLIARLATYLKENVPEVKPLPWAYFVKTGAHKERPPQDP-D-WWYYRAACILRKLYKCGEPIGIETFRTIYGGRKN--YG--SAPEHFVKCGGCIIRRILQQLEQARLVRKIRG--RGRILTPQGRALLDRLADATNQILGRLACIIAGYR-VIVVNAEKAVVCGERVRVIQGYK-LIEKVTTHYNPYKTGVRRPKCPHNILKRTVRGMLPM-DKPKGGKANPGPPLGPTLCPLRVNVMEVVKAINEATKDFE--GLTVP-VEIIV-DTCTRKFEVKVGIPTTTALLLKEVGVKQ------PPGDPAH-QKIGDLPIDKIIKIAILKKEQLTAKTLKAAVKTILGTARCIGITVDGKDPKIVQKEIDEGKAGMCHAIIIDDRPHTFTCGKEIAIPVTVLDAPPILILGLRG-YKIHPMHG-LLCFGEGNYVTVDQVFREGQFIDIIGVTKGKGFQGVIKRFGVKELP-RWHKHRKGCRK-IGCRCP---GFGTMCETPQPGQMGFHRRTEYNGFLGYGIVYGPYIMLHGCIIGPRKRLLVLRHPIRG-GIHPREAALHHAVALGPGLGPCLRVGACLARFLCCYYNIPLIPVNHAVAHIEIGKFLF-----GFKDP-LIIYVCGGNTLIAIQRK-KRYRI-LGETLDIPIGNLLDTFAREIGLAPPYIVNGKHQVDICAE------WG--SEFICLPYTVKG-----SDLCFCGLLTETAFNMLVEVAERCGGVACNKVLRKKLELM-ACLHGAKYAGTPPEYCGDNGAMIAYTGLLGYLHNKIKIWCNNINILNEFMNKITDIVKRTGVKMCGPIPLPTKRLVVRTLKLPHGEGKKKWEKWEMRIHKRLLYI-AADERVMKQLIRVRV---PPEIWMEIIKFGILCPEEIRKMCVTTIITCEVYDNDGA-PIDGGVMDRRL-GAIEPREVCPVCGNTRECC---PGHFGHIELARPVIHVCFVK----HIHMYLKTTCRVCPH-------CRARLEKILD--EDR----PEWMVLTVLPVPPRCVRPCILLETGIRCEDDLTHKLVDIIRINNRLREHIECGAPNAIIEDEWELLQYHVTTYFDNEAPGI------PVARHR-SGKVLKGLAQRLKGKEGRFRGNLRGKRVDFCARTVICPDPNICINEVGVPEVVAKILTVPERVTPWNIEEMRRLVLNGPDKWP-------GANYVERHLRDGDIVLFNRQPCLHRICIMAHVVRVLPYKTFRLNLLVCPYNADFDGDEMNLHVPQCEEARAEARMLMLV-EKHILTPRYGGPII--GGLQDYICGAFLLTGKQLICLFLPDGYHRGELEPRPGRTIEETLEDEINPVIIMARTGARGNPINLTQMAALLGQQTIR--------GRRITRGRTLPHFKPGDL-GPEARGFVAHGFVDGLNPIEVFFHAAAGREGLTDTAVRTCQCGYMQRRLINALQDMAK--VLVLLKVLPEDINIDLEELE-PIAFGLKALRLYIFMPEETEGGTEPLENTVMNVEGVVNGPKGCIERDFCHVRNIILRKENCK----ITIACHIENMIKGVLKGYRYKLKIIYCHFPITVEVDDRNRIVRIKNFLGEKCDRIAKII-GEDVKVTV---KG-ED-IIVEGIDIEHVGQTAANIGIDEAGRGPLIGDLVIAVLDCKQLTRHTRLIMAKKIDQKYPVVCAACILAKTIRDKNIDFLKK---IYGGRIRRPLLVVE---NGGIIEYLDADEGITACIIPYAEHNQCPRNCYEAAMAKQGLYCAN-FQQRMDTRGHLLHY-PQKPVQTRAMEVNG--YNERPA--------GQNMVVAFTGYNIEDALIMNKCCVDRGLARCTFFRLYTTVEYRYPGGD-RIMIP--PCNVR--GYRGPKAYEKLDE-DGIVCPETPVRFMTAQEYTV---GA--GITRQDACRHGEKGIVDVVLVKVRVRDLRGDKFACRHGQKGVIGLLVPQQDMPFTENPHAFPCRMGQLIECIAG-------KGYETMYDGRTGEILKTPIFIGIVYYQKLHHMVADKIHARARGPVQILTRQPTEGRAKEGGLRFGEMEVDCLVGHGACLLLKEQMLDKCDKTTIYVCEL--CGYAFKLLVQELMCMCIMPRLDAGLFIDALKGFPGPYEKTCGIITRNPRGEQ-GFGFDPIF-IP-------KGCC-RTFAEMCIDEKKTCIARAVIKPGEGRVWINEIWPI-ELARLKMYEPDIYVNVRGGGVMCQADAVRMAIARLRKIFTEYDRYMLCGDPRRTEPEK--WGRYCARRRWQKCYRTKNLVPGHRVYGEREWNLYRCKLLYLGVATGTTACHICDIVGPTGRIFCVEFAPRIAQPEQAAIVADNGYLL--LAIKA-----RCIDVTKEPCEIYRR-EINTLVFYNPIMRVN--RDDVDPICYYYIRRNDIDPYGCPIPFIDCAVKP-LGKKCLLGITATDTGPLNCCHKNKALRRYGIRCI-KTDFCRELGLRILLYNIVFRAACLDVALY--PLICYCHKHYYRAIFQAERTGRKCYEIIDKCRGLYGPAGCGKTCLVEAAALKRICQLE-------KLECEDAALREIARRCEGDLRCAINDLDPGLKRYLCLKPVFLPHTGGRHEHRRFGKAEVPIVERLINKIMGKKHLAYNIVKKAFDLIYLKTGENPIQVLVRAIEYAAPREETTRIMYGGIVYHVAVDIAPQRRIDLALKHLTDGARNKC-FNNPLPIEEALAEEIILAANND-PR-SYAIQKKEEIERIALCCRRGRTRCMGWGRIGQHRKCGARGGFGAVGF---HKHKWI-WVLKYAPN-----WYG--KHGFKVLGRGKVTLPLKIITKCICKRAREKITAVGGGKTLEELL------NMPMDEFIGLLPARQRRCLKR----GIKTHVRDMIILPEMIGLTIAVYNGKEFIPVRIVPEMIGHYLGEFCPTTKRVQHGEPGLKATRCCMFICLKADNCGAKLVKIIGVPG-Y-KGRLRRIPPAGIGDLVVVTVKKGTPE---MRKQVVKAVIVRQKRPFRRPDGTWVAFEDNAVAIVTPE-GT-PKGCEIRGPIAKEVAER-WPQLANIARLAAEILGVGECRIWI--DPERIDEVADAITREEIKALIKDRVIQVKPIHGNCRERWKIRHMQRK-KGRRRGYGKRKGKKTARK-DRKEEWMNRIRKIRRFLRYLRDHGV-ITRKDYRRLYMLAKGGTFHCLACLWVPRTRVGKMVVEGKITCLKEIFDRNLPLLEPEIVDYLL-PDLGRRCRFRVVVVVGNEDGFVGVGCGKARQYLVALRKALRNAKLNITPVRRGCGCWECRCGEPHCIPFTVQGKCGCVVVVLKPAPKGTGLVAGDTAKAVLRMAGIKDVWTETFG-----KTKTTLNFAKAVVNALEFLANYFKDAGYAGMELYKT-PTGYRVVIYAEYPGRIIGRGGCIIRKLMTIMQTHFG-LENVNITVCPV---PDPDLNARIVAFRIVRALEKEIP-YRRVAMAMLRRVMEA-GAVGAEIIICGKLRC-ERARYEKLKAGRIYKAGDMVDYVVDRAVGKALLKRGVYGVEVVIVRP--HLKPPDLRRILTPEARCRLANLRLVKPELANIVEQQLITLAQCGRVPVPITDNFLKKLL--------VTGVLPVALANATKVIGNVIHTIKEYFTGVIYQRPPLRCCVRVIRTRRIHYIDL--LGTYMRKLAHDIGLLLGVGAHMRELRRTRTGPYKEDETL-VRMPVETAIAHLPKIIIRDTAVDAVAHGAHLAVPGVAILTLKGELVPTVEKPKAKPGLYERL-LWTAIALIVYVIMANTPLYGG--TLMELGIGPIVTAGLIMQILVGA--KMINLDMCN-PDDRRRFTAAQKQLFI-ATYIVILLDEMIQKG-----IGCGVCLFILTGVTFVIIFLLVYLEGMKVEIPPLKFLYVTNIPVLFGIM--WVEICGLCA-SAQAEELIKCGMEIPGIRRNPKILERILCRYIFPLTVLCCLIVALIAVTADLM---GAYG-------TGTGILLAVGIVQQYYTMIAYERTLEAYPLYRNKLFKIGE---YRLTCGKICYIDLRILPCYYP--V--GYVRKKPKGTKRL--VEG-IVA---DRNVLVVDDVATTGGCLEHAVNAVRCMGGLFAARKLRRKRLKFRWCQREFKIKML-GLKKKHDPLEGA------PMARGIVLEKVGVEARQPNCAVRKVRVQLAKNGKVVTAFVPFDGGINYIDEHDEVIIEGIGGPRG-RCMGDIPGVRYKVIM--VNGVCLKALYLGK----KQKPVRLIPLEKYL-----AAGVHIGTHIC--TKFMEP--FVYRVRN-DGLYILDVRKIDERIRIAAKFLCRY--EPCKIAAVCVRTYGQKPVVKFCNYVGCKPFTGRFMPGTFTNPCLKWYFE--------PDIVLLTDPRADCQALKEAAEIGIPIVCLADTDNRTEYIDLIIPANNKGRKCLALIYWLLAR-QI---LRERKQVIIVRTDIKMCKGKLAVQVAHAWWATGQKKIVVKGGCERDLLKYAEMAKKKDLPVAIIRDAGLTELPPNTLTAVGIGPGPCRKIDEITGDLKLKYVFITGGVLCGLGKGVITACTGLLLKCIGYCVTAIKIDPYVNVDAGTMNPYMHGEVFVTED--------G-----GETDLDIGHYERFLNQNLTKKHNITTGQIYYCVIMKERRGEYLGKCVQIIPHVTDEIKERIDIVLVEIGGTVGDIEGLPFLEAIRQMRIEEGYGNTVAIHVALAPIICT-GEQKTKPVQHCIQELRRIGIQPDIVVVRCPRELEEENRAKIALYCNLCKEAVYCDPDVDIIYRVPIILHRQGLHDCYLCIIEALKHDGAVILPGFGKRGAEGKIKAIRFLRENNKPLLGICFGMQLMVVEYARNVVGLERAHCTEIDPNTPYPVQYNV----KHLGGTMRLGAHPIHIKKNTIAWQIY-RREIVYERHRHRYEVNPK-YIDKLENAG-----LKIC----GW--SPEKYPEFIEL--PK-YRTLYFGCQPHPEFKCRPLTPAPIYRNFKQCVELIVVLKDVDPRC-PEGRIRETIFLPKGLG-KDKIICVVADGEMAEKARAGGAHRVITRDEL--LALCKKDAKKVAQECDWVLVRTDLMANAGRIL-GPALGPRGKIPILLRNKDQPQLMTRIGTEDMNPEDLVINAQTILCRLETKLPNGAH--NIAKIVVKTTMGMGDPKKP-RKKWEG--PRHPWRKEVLVQELKLLGTYGLR---NKRELWRAQTIVRKF-RH--QARCLLYRLGLL---HENACLEDVLGLTVEDLLERRLQTIVYKKGLARTIYHARQLIIHGHIAIAGRRITCPGYIVCREEEDLVIIRPVHCEKALNLIDKENTLTFIVDRNACKKDIKDAVELVFGVKVLKVRTKKAYVKLAPEH--RACEIACQLGVFCCDGEKVEEITL-PPIFCLPVRKDLIRRAFLCAFTCMLQPKGRDPLAGKRTTA------RCWGV--GRGLARVP-R--LPNCR-------AAFICFARGGHAAFPPRPDERIHERINKREKAYAVACAIAATAKVDLVRGRGHVFQQ-DKL--PVVLLDDVEDKICKARDAKELLIKLGLWCDIVRCYERI-RIRAGKGKMRGRRYVEPRCILFVNFPGVDVATPNNLGILHLAPGGVPGRLTVFTRCAARYEAKGHRFEILVNPDLALKVK--EGK-T-VNIDELLVGDYVYKDARKGLKACPECLKAVFGTDDIKKVALEIIKRGEIHLTAEQRRKIIENKRRQIICLIARNAIDPK-TKLPIPPKRIELAMEQARVCIDPFKCPECQVEEIVCKIARIIPIKIAKAYIAVKVPPQFCGKAYKVLCCIG--EIKKCNWLCDGCLLVEI-EIPAGMQEEFIERINKLTHGVCKIRNGIVIDHIPAGKA--------LKVLRVLGITG-SEGLR--VALVMNVECRKLG-R-KDIVKIEEKFLCMKELCLIALIAPTATINVIKEYKVVEKQRVEPPCIVKGL--IKCPNPTCICRKKN-EPIKCLFKLK-STN-PIMLECQYCTNIVLRKTIRELKKLCKQYKTAIWKAVAEELEKPRRQRR--AVNICRINRHTCCG-----DVVVVPGKVLGCGNIDHP-VTVAAVCFTKTAIEKIEIAGGKA--IHILDLAR--ENPRGCNVKIPVRCFTCGAPIGHLWEEFKKRV--EAGE---DP-----GKVLDDLGVKRYCCRRMFLCHLKPGNFIII------DGEPCRIVEMCKAKTGKHGCAKAHVVAIGLFTGNKKTLVAPVDQRVEVPVIEKRVGQIQVMDMETFETGVEVEYWVV-MGKRMIKYLINARVEVDGVVDI-----IGAFGQTEGLFGEQF----DLRTLQDKNRIGRIA---AMIECVDR--------VGPYCARIEVVDIIDVRLEKIKKIIDRAVDECDTIIIVEGRAD------VINLLR--YGFTNVIAGARK-VPNTIKNLAKKKKV--IVFLDGD--------HGGDL------ILKELLRT-IKVD---FIARAPEGR-EVEELTGKE----IREALDKACEK--KVKMIIAAKIG-RI-NYKPMYKPRLAKVTVNICVGAA---TERLCKAMQVLEELT-GQKPVPRRAKRTIKDFGIRKGENIAAKVTLRREKAVAFL-KRVLE--AV---NYR-IKACCFDDNGNVCFGIKEHIMIPGVKYDPEIGVFGRIIITRPPEITAVRP-LKKLCLEDYILIAGAPGMGKTTFAQALAEYYMRQ-GK-VVKTIECPRDMNLPP---EITQYCKNYA------DLGELHDIL--------LLCRPDYTVFDEMRCDEDFKLYADLRLAGI-GMIGVVHATTPIDAIQRFIGRVELGMIPCL---IDTVIFIKNGYVDKVYEVRMTVKLPTGLKE--AELCR-------PV-VEVRDF--LTDELEY-EGNDLRKPTGG-KKTRHRK-KRKHELGRPPTMTRFC--VKE-AQKIIRVRGGNLKIRLKRAVYVNVAVPNEGKVTKTRILEVVETPCNPQYARGNYITKGTIVRTELGLVKITCRPGQDGVLNGILAGEIAKKVREEAARIAEPGMKLFELAEYVERRIR-ELGGEPA------FP--VNLCINEVAAHYTPVVDDNTIIPDNAVLKIDLGVHIDGYIADTCVTLLEACRMALEKALEIVGPGIRVNTIGKVIEETITCYGYKPIRNLCGHCIDRYLIHAGKC-IPNG-VYAIEPFAT--NGVGLVREGPIATILIERGGGLVCQFEHTFIIHGKDVIVTTCK-PNKCN-LECIRFCPIYEDICIG--CGICVKKCPFNAICIVNLPDELEKN-VVHRYGENMFKLYNLPI-PRLGNIMGIIGRNGCGKTTCIKILCGLLKPNKIQ-----YVEL---VKRRL--KGR-VGELLKKADER---G-IDREVVDKLAIKHVLDRKICELCGGELQKFLVAAVLVKEADAYFFDECCCYLDVKERLRVAQAIREFIDVC---KKYVMVVEHDLMVLDYICDQVCIIYGEP--GVYGIVCKPYGVRTGINHYLEG----YLPAENMRIRFKLFIEAGE-AYPGEVLGIIGPNGIGKTTFIKLLGG--VLEPDE------GF-------KPQEL-SPKIF-PEETVAANLLCGGELQKLAVAVALAKQADLYLLDEPCAYLDVEERLTVAKVIRRIIEEKRKTAMIVEH--------D
Sulfolobus_acidocaldarius_DSM_639                       GAE-IALAGCNPLCT-----QDAWRGETEKDYYDNIREILK-----YEPHVIMDDGGDLHAYVHGGTEETTTGVIRLKAMEEEKVLKYPVIAVNNAFTKYLFDNRIGTGQCTIDGILRATNILIAGKVAVVIGYGW-VGRGIACRFKGMGAR-VIVVEPFRALEALMDGFDVM-TMNRADIFVTATGNLNVVCRDHILRMKDGAVLANCGHFNVEIDVKGLKEI-SVETREVRQN-LEE--------YKLRN-GKRIYLLADGRLVNLVA--AEGHPCEVMDLCFCNQVYNVPIEIDEQVARLKLKALGIEIEELTIEQKEYIKQWDIGGMKEIIQKIRELVE-LPLRHPELFKRLGIEPPKGILLYGPPGVGKTLLAKAVANET-----DAYFTCINGPEIMCKFYGECEQRLREIFEDAKKHAP------AIIFIDEIDAIAPKRDEVIGEVERRVVAQLLTLMDGLENRG------NVIVIAATNRPNAVDPALRRPGRFDREIEIPLPDKQGRLEILGADLCALVREAAMNALRGPPGTGKTMLAKA---VATECGANFIAVRGP--EILCKWVDEIDCIAPIRGLC-TDCGVTERIVNQLLAEMDG--IEKLENVVVIAATNRPDILDPALLRPGRFDRGNARIYACQNNTIITITDITGAEIICKACGGMVVKADREKPCPYAAMLAANKAANDAFDKGICAIHIKVRAQGGY-GCKTPGPGAQPAIRALARAGFIIGRIEDVTPLPHDTIRRPGGRRGRRGIAGRFGARYGCCTRKKWKEVMERRYMPHQCPYCKTTGKVVRIACGIWYCRKCETKWAGLAYTPVDEGAVKRVTDGADLFVPGIVCYNCECKEGDVVGKFGVNLHYVCDYHYIEQTWQNK---DWRRCILRKRLIEWRRQPAITRIDRPTRLNRARALGYKAKQGFVMVRVRVRRGGLNKPRPNCGRRPKRMGVYGYGP-SKGYRWIAEERAARKFPNLEVLGCYYVAEDGMYKYYEVIMVDYCHPVIRCDPELKWLQDCVNRKRVFRGLTCAGQKCRGLIIDILHNPGVTAPVVKVKLD---NGLQFYIPAVQGVAVGQEIGKNATICNGNIVEVGQLPEGTVICNVEKLKGDGGKFARAAGCYALCCEKIVEVCQNARATVGIIAGGGFVEKPLLKAGNNYWKYRVRAVKWPVVRGVAMNAVCHPHGGGLHQC-VC--RPCTVCR-NAPPGRKVGHIACRRNIGIIAHVDHGKTTTCDTLLAACGIICQ--KVAGEALALDYLCVEQQRGITVKAANICLYHEIDGKG----YVINLIDTPGHVDFCGRVTRCLRVLDGCIVVIDAVEGIMTQTETVLRQCLEERVRPILFINKVDRLIKELKLCCQEIQKRLIDLIIEVNNLILDAVIKFVPNPRDCQKYRIPKIWKGDLDCEIAKAMINADPNGPIVMMINDMKVDPHAG-LVATGRVFCGTLRAGEEVWLVNA-KRQQRILQVCLYMGAIRELAEEIPVGNIAAALGMDAARCGETEKLHYICEPVVTICVEPRNPKDLTKMIDALRKLCIEDCNLVVKINEETGEYLLCGMGFLHLEVCLQ-LLKENYGLDVVTTPPIVVYRECIRNKC-QVFEGK------SPNKHNKLYICVEPGVQHLREIMDTLLQGFRLAMKEGPLAFEPVRGVKVVLHDAVVHEDPAHRGPAQLYPAVRNAIFAGILTCKPTLLEPLQKLDIRIPMEYLGNVTAVITRKRGKVINVVQTGNV-ARVYAEIPVGECFE-LACELRACCAGRAFWGTEFCRWAPVPNPLANALATLYNNEMRRNKQALITPACKLIICVLRVMQKEGYIGEFEYID-DGK-IIVQLLGR---INKCG-------PICPRYPLDYNGLLRLPDYIR-KYLP--SKEIGIIIICTPKGVMCHRDGIREKIGGVTLGYVYGAGQVVLLGDHEL-KNRLMRELTPPLI----FEAKCLIGRVLG-LTKNCDLE-------GFGIRNALREAIFKILDVIRVYTKEPKDKPC-MEPFGY-----ARVGADHVLED----GDMITVQMVPADILIPKLAEYLKNNVKELNPPNWVYFAKTACFKERVPDDI-ENWWYIRAACLLRHLYIYKEPIGLQKTRKLYCGCKR--RG--TKPPRCVKAPTHCIRTILQQLEKAGLVTKTRR---GRILCPKGRCLLDKLADATNQILGRMCTHIAGKK-VYVVNAEKAIICGPRCRVLEGYC-LLFTVKTMQNPYRQGIRRPRNPINIVKRTVRGMLP--KNKLGGCAKPGPPLGPTLCQLGLNVQEVVKKINDVTAQFK--GMCVP-VTIEI-DCCTKKYDIKVGVPTTTCLLLKAINAQE------PCGDPAH-KKIGNLDLEQIADIAIKKKPQLCAKTLTAAIKCLLGTARCIGITVEGKDPKDVIKEIDQGKAGMTHVYMIDDKPTCPNYGKEVYTPVTIVECPPILGLALRA-YHIDCKGE-LCVLVDGKQIPVRDVFREGQLTDIIGVTKGKGFQGVIKRYCVVEFP-RWHKHRKGCRK-IGARGP---SICTPCYVPQPGQLGFHRRTEYNGIVNYGLVKNTYLVIEGCVLGCRKRPLFLRYPIRG-GMKPCELARHHAVALGPGIGPALRVGATVARALALCFNKKLIPVNHGIAHIEIGMYCT-----NAKDP-LILYLCGGNTIICIFFD-RKYRV-FGETLDIALGNMIDVFVREAGLAPPYVVNGVHQIDICAD------KG--KEYVELPYIVKG-----QDMCYCGLLTEIAFDMLLEATERAGGVAACVCLKCKLEKL-AADRGAELKIVPCQYCGDNGAMIAYTGLLAAKHRRIRLWCCNIDCLNFVVNQIRNMAQKTGIQVCGPIPLPTTRMEVPVMRLPHGEGKKKWEHWEMKVHKRIIDI-AADERVMRQLMRVRV---PDDVYIEIVKFGVLCPNEIRQMCVTAIITCEVYDEDGT-PIEGGVMDPKL-GVIEPGQKCPVCGNTLAGC---PGHFGHIELIKPVIHIGYVK----HIYDFLRCTCWRCPH-------CRDRLERIPD--SDR----PEWMILTVLPVPPITIRPCITIECGIRAEDDLTHKLVDIIRLNERLKECIEAGAPQLIIEDLWDLLQYHVATYFDNEIPGL------PPAKHR-SGRPLRTLAQRLKGKEGRFRGNLCGKRVDFCARTVICPDPNLCIDEVGIPYTIARMLTVPERVTNINIERIRQYIINGPDKWP-------GANYVERHLVDGDVVLFNRQPCLHRICMMAHKVRVLPGRTFRLNLLDCPYNADFDGDEMNLHVPQCEEAIAEARELMLV-HKNIITPRYGGPII--GGGQDYICGAYLLCGKQVICLFLPDGFNEGQLEPIPGRTIEECLECYINNVYIMAITGARGCELNITQMTALLGQQCVR--------GERIRRGRTLCLFKYGDI-APEARGFVKNCFMRGLCPYEMFFHAAGGREGLVDTAVKTCQCGYMQRRLINALCD-AD--VLVILKVFPECDEINLTQLE-PIAYGLKALIAYIQMPENTEGGTDKLEELVNGIEGVVKGPKGEVIKDFCYAKGIRIQLNEGK----ICIIAHIKNMITGTINGYRYYLKVICTHFPICVKVCGDE--VQVCNLIGEKNIRRAKIL-P-GVKVTV---KG-ED-IVVEGCDIYNVAQTAANIGIDEAGRGCLIGPMVVAGVDCKKLTRKKREYLFGVIDVKYVEVCAACIIAKVVRDNIINELKK---TYGGRVRRPLIIVN---NGGKIEFIDAEEGIIACIIPYPEHNQCPRNTYQCAMAKQGLYACN-YQIRTDTRAHLLHY-PQMPVQTRMLGVIG--YNDRPA--------GANAILAYTGYNMEDCIIMNKCCIERGMYRCTFFRLYCTEEVKYPGGD-KIVTP--EAGVK--GYKGKDYYRLLED-NGVVCPEVEVRFL--QEFKEL--SP--EQAKRDTCRHGENGIVDLVLVKVRVRDLRGDKFATRHGQKGVVGILIDQVDMPYTANPHALPCRMGQIMEAIGG-------KCTEVVYDGRTGQKLKCRILFGIVYYQKLHHMVADKMHARARGPVQILTRQPTEGRAREGGLRFGEMERDCLIGFGTAMLIKDRLLDNCDKAVVYICDQ--CGYAFKLLIQELMCMVICPRLDCGLFIEALNGFPGPYGRVYGCICTEIRGTK-GFGYDPIF-IP-------DGVN-LTFGEMCTEEK????????????????????????????????????????????????????????????????????????????????????????????????????TKNLCPGHNVYGEREWNAFRCKLLYLGAACGTTPCHICDIVELQGKVYCVEFCPRIAQPNETEIAMYNGYMM--IAIKC-----RCIDVTKDPREIYNA-EAKKLVFYNPKMILN--RDDIDCDAVELIKKNDIDPFGCPAPFLLCCFCA-AKCKQYVAITATDLAALMCCCKTCARRKYGLICN-KMCFCRELGLRGLICKAITEAAVVEKAVT--PVFCFYNDYYYRVIFKVERGAKKVDRQLC-KLVLYGPPGVGKTTLAEALALKRICEKE-------KIVCIDEALDHIIEQCEGDARYCINMLDPCLKKYIDLMCIYLPHTGGRHEHRRFGKCRIPIVERLINNLMGKKMLAYNIVKTTFDIIAVKTGQNPIQVLVRAIENAAPREEVTRIMYGGIVYYVAVDVAPQRRVDLALRHLVTGACEAC-FNNPKPIEEALAEEIIAAANND-NK-SVAIRKKEEIERIALCCRRG-YRTHGWGTKGQHRDRGAQGGR-QIGM---HKEKWC-WTVKFGEG-----WYG--KHGFKLLGGGNLRLPLVIKVAKATEKAKERVKEIGGGKCLEDLL------NMPMDEFIKLLPCRQRRCLKR----GIKTHVRNMVILPEMVGLRFAVYNGKEFVEFQVVPEMIGRYLGEYCITTKKVEHGEPGLKATKCCLFLAMKADNCGAKEAVIIGIYG-Y-RGVLRRVPFANIADLVMVCVRKGCPD---VRKQKFKAVIVRQRMPFRRPDGTWICFEDNAVVIINPD-GT-PKGTEVRGPIAREAAER-WPKIACVARLAADIAGVGLNNIKF--NPERLEEVEEALTREDIKKLIKERAVIVNPKRGICCGRLKERKHKRRCKGEGRKHGCRKGKCGART-GDKEIWINKIRKIRRYIRWLRDNNV-IDKHTYRLLYKRAKGNYFKNLCDVWKPRTKVGQLIKEGKINCMKELFERNLPIVEPEIVDVLL-PKLGELCRYKVLIVMGNMDGYICYGTGKAKQLRVAIQKAIRDAKMRIIPVRRGCGCWECTCGECHCLPFIVCGKAGCVEVTLLPAPKGTGLVVGCVLKTFLCLAGLKDVWCRTKG-----STYTHENFIKAAYIALEYLAKQFYNAEYAGVEIVKT-PIGTRVIIYAGRPPLIIGKGGKTIKQLAQVLEKFFG-LENPQITVTAA---ENPELNARVMAFRLAIALEKGYH-FRRAAFITIRRIMCC-GAVGAEVIVCGKLTC-ERAKYEKLKEGTVYKCGQQLEKIIDRAIGIAMLKPGVYGVEVVITKP---TRCIDLRTILTPEARQRLTNVKLVRPELAEAIENQLIALAQCGRIQAQITDDELKQILHGGTLEP---------------VMNYICKCGKEYFVGEIYQKPPVRCCVRRIRKRRIYAIDI--LGTYMRKLCHDVGVIAGCGCHMRELRRIRCGIFTEKTNM-VTLPMEYGVCGIPKVIVCDTAVNAITYGAKLNLPGVAVLTLKGELVPAVCKPKDKPTLTRKL-LWTFIGLIVYLLMACIPLYGG--TLAQLGIGPVITCGLIMQILVGC--KLINVDLTT-QEGKCKFTQAEKQLII-ACYIILLLDEMIQKG-----LGCGVCLFIMAGITVGLTILIVYLVNTNIYIPPLNFLYVCCIPVIFGML--WIDVAGLDP-KTQAEQMIRCGIEIPGMRTNPRIIEGILCKYIYALGFFCCLIVGLIAVVATFL---GTYG-------TGVGLLLAITIAMQYYNLLAYERTLEMYPLLDKKLLLIGN---FMLTCGKVCYLDLRKLPNHPP--M--GYIRAEKKGTERL--LEA-DVD---GKKVIVVDDVATTGGCILKAVEEVRKAGGLFAARKLRLKRLKFCWCQRCFKRRML-ALKEKFDPLEGA------PMARGIVLEKVGIECRQPNCAVRKVRVQLVKNGRIVTAFVPGDGGVNFIDEHDEVVIAGIGGTLG-RCMGDLPGVRYKVVM--VNGVCLDALYKGK----KQKPVRLVPLDTYL-----SAGVHIGTHTC--TRYMER--FIYRVRP-EGLYVLDVRKIDERLRVAAKFICRF--RPEAVLTVACRPYAFTPVQKFCEVVRGKEICGRFPPGTLTNPYLDNYIE--------PEVLIVTDPRTDLQAIKEACKVGIPIVAFTDTDARVDFIDVIIPANNKGRKCLALLYWVLAR-QI---LRERKMAVLVRTDLDMGKGKIAAQVAHAWINQGQPKIVLKVKNLDELLEKYNKALQCGLPATIIQDAGKTQIEPGTITCAGIGPGPEEMIDNITGDLKLKYIIVTGGVLCCVGKGTIVACIGFLLKCCGYNVTAIKVDPYLNVDAGTMNPYMHGEVFVTDD--------G-----AETDLDLGHYERFIGINTTRYNNITAGRVYFEVIRKEREGKYLGQTVQIIPHVTDEIKGLVEIAIIEIGGTVGDIEGLPFLEAVRQMKLEEE-ENLMFIHVALVEYLRVTGELKTKPLQHCVQELRRIGIQPDMIIARCILPLDEETKKKIALFTNVKPDYILCNYDVELTYEVPLILEKQNLKDCYLCIKEAIYHNGIIVLPGFGARGVEGKIQAIKFARENNIPFLGICFGMQLAIVEYARNVLGLKEANTTEVNPNTKYPIQKKI----VQVGGTMRLGAQKIILKEGTLAYCIY-NCPHIYERHRHRYEVNPE-YVDLLQKYG-----MIIC----GVC-ENG-LVEIIEL--KN--HKFFLGTQAHPEYKCRPLCPCPVFRNFTQCVEIILTFKGIDMKK-GDLKLREIVPLPKQPC-KAKRVLVVPCFEQLEYAKKACPNVVITREELQKLQGQKRPVKKLARQNEWFLINQECMALAGRIL-GPALGPRGKFPVLVKTKDQPQVQVFIGTEDMKPEDLAENAIAVLNAIENKAKVET---NLRNIYVKTTMGMGDPRKC-KKKWMG--PCHPWIKINLGKEQILIGKYGLR---NKKEIWIAQTMIRNF-RH--QARCLLYRMGIL--EKDNCTLDDILCLTEENYLERRLQTIVYKKGLARTIYQARQLITHGHIAICGRKVTCPGYVVLRGEEDLIIKEFLATEKAVKLIECQNTLTIIVNRNTTKKDIKNEVEKLFCVKVEKINTKKAYVKLKQEY--KACDVAHKLGVLDLKGNQLEEIEL-PLFFCYPVRKDLIRRVFLCEFTKCLQPKGRDPLAGKRTCA------LCFGI--NLGIARVP-R--VKGCG-----E-AALAPNTVGGRLAFPPTTEKRLVEEVNLKEKKLGIICALAATADPNFVKARGHRFTC-NNV--PIILVDDFEN-ICKAKEIMDILKCIGVVDDIKRVKECK-GVRAGKGKMRGRRYQIAKGPLIVNIPGVNVVCANLVCVIHLAPGGHPGRLTIYTKCCARYEHCGERFEILVKPKEAMDLR--NGK-S-VCICDAVVCDTIYKDIKKGLKACPCCLKKVFGTLDFEEIAKQIILKGEIPLTAEQRREILENKRKQIIDYICRNCIDPK-TNLPIPRTRIELAMEQARIQIDPNKDVEAQALQIVRELAKLIPIRIARALMEIKVGPKFCCKIKCQLANLG--EVKRCNWLNDGTLIAEL-EIPAGAQQDVIDKLNCLTKGVCKIKNGTVIDHIPAGRA--------FAVLNVLGIKG-HEGFR--IALVINVDCKKMG-K-KDIVKIEDKEICDTEANLITLIAPTATINIVREYEVVKKTKLEVPKVVKGI--LKCPNPYCITCNDV-EAI-PTFKTL-TEK-PLKMRCEYCTNIMLRKLITCLKKQ----DKAIWVRVAEELEAPRRKRA--YINIYKINRYCKAN-----DIIVVPGKVLGVGNLDHP-VTVVALCFCKPAKEKILRCGGKV--MCLYKAIQELNDFKGKTVRLPIRCFTCGAVVADKWEPFCNRV--MGGE---DP-----EKVLTELGVNRYCCRRMLLCHLKVGCYVMI------DGEPCRVVEITKAKTGKHGCAKANVVAIGLFTGQKRCLMAPVDQQVEVPIIEKHVGQITIMDLECYETGAEIEYWCV-MGRRKIKYNIVFKFNVEGIVDV-----IGAFGQTENLFGDDF----DLRELQDKGRLGRIA---AMIENVDK--------VGPYNAEFKLIDIVDIREEKIKKIIGRAVDKDPELIIVEGRAD------VINLLR--YGYKNVIAGATGKIPQTLVDLTKQKKAV-IAFLDGD--------HGGDL------ILKELLCCNIKLD---YVARAPTGK-EVEELTGKE----IAKCLDLACAK--NIKMLIGARIG-GI-NRRPMRRVVLDKVTVNIGVGEC---GERLQKAYQLVQELT-GVKPVYTKGRKCIREFGVRKGAPIGVKATLRRQAAVEFL-KKVLP--AV---NFR-LKQCCFDNYGNVCFGIAEHVLIPGTRYDPEIGIFGRVVIIRPPEVTITRP-VVKKKLEEYILIAGCPGMGKTTFAQALAEFYTRM-NK-VVKTIECPRDMHLPP---EVTQYCKNYA------EVGELHDIL--------LLCRPDYTVYDEMRNDEDFKLYIDLRLAGI-GMIGVVHATCPIDAIHRFINRIDIGTIPNI---LDTVVFINCGNVAKVYGLDITVKVPTGLKE--ADLAR-------PV-VEVKDL--ICDKAEY-EGNDCRKITGG-QKGKNRD-KRKYELGCPPTETKIC--DKD-IKEKDRVAGGNFKLRLRYACYANVYDPQCKTAKKVKIICVLECPANREYARRGIIVKGTLIQTELGKAKVTCRPGQDGIINALLAGKIACKARDFGAKMIKPGVKVIDVCDTVEKIIE-EEGAKPA------FP--CNLCINVEAAHYCPIINDTKIIPENAVVKLDIGAHINGYITDTAVTLVEACREALQAAIRTIRNGVDIGEIGRHIERTIKCYGFKPIRNLGGHLIRRYELHAGIF-IPNGCTYAIEPFAT--DGEGYVIEGKEVTILLEAKKGIVAQFEHTVLVLKDRVEVITCK-PDKCR-LECIAFCPIYEETCIG--CGICIKKCPFDAIDIVNLPDEYGKD-ETHRYKVNGFKLFGMIT-PKKGCIIGILGKNCTGKCTILRILCGELIPNKIQ-----YVEY---ACKYL--KGC-VKDLLTKVDQR---G-KIDEVKCMLNLTPFWEKDVCVLCGGELQKLLVCACLLRDADVYLFDEPCCYLDIRERINLAIAIRELTK-----GRYTIVVEHDLIVLDYLADVIHIIYGKC--SVYGRVCKCYCCRVGINNFLHG----YLPAENIQIRFCLCIEEGN-AREGEIIGIVGPNGIGKTTFMRILVC--EITPDH------GY-------KPQRL-APN---YEGTVQEYLLCGGELQKLYVAGALAKEADIYVIDEPCCYLDVEERYIVAKAIKRVCRERKCVTFVVDH--------D
Thermococcus_kodakarensis_Kod1                          GAE-VCAAACNPLCT-----QDAIRGEDREQYYEFMHKALD-----VKPNIIIDDGADMVCTVLGACEETTTGVIRLRAMEKDGVLKFPIIAVNDCYTKYLFDNRYGTGQCTWDGIIRTTNLLVAGKNVVVVGYGW-CGRGIAMRARGLGAT-VIVVEPIRALEARMDGFLVM-DMMEADIFITATGDINCIRKEHFELMKDGAILANAGHFDVEICKPDLEAL-AVEICEPRPN-ITE--------YKMAD-GRRLYLLAEGRLVNLAA--ADGHPAEIMDMCFALQVYVLPREIDEMVARIKLACMGIKIEELTEEQKKYLECWDIGGLCDAIQKIREMVE-LPLKHPELFERLGIEPPKGVLLYGPPGTGKTLLAKAVANEA-----NAHFIAINGPEIMCKFYGECEERLREIFKEAEENAP------SIIFIDEIDAIAPKREEVVGEVEKRVVCQLLTLMDGLKCRG------KVIVIAATNRPDALDPALRRPGRFDREIEVGVPDKQGRKEILGADLAALAREAAMVVLRGPPGTGKTLLAKA---VANECQANFIAIRGP--EVLCKWVDEIDAIAPARGCE--GDRVTDRLINQLLTEMDG--IQENCGVVVIGATNRPDIIDPALLRPGRFDRGVAHIYCCYNNTIIHITDLTGAETICRWCGGMVVKADRDEPCPYAAMIAARRAAEEAMEKGITGVHIKVRAPGGC-KCKCPGPGAQAAIRALCRAGLRIGRVEDVTPIPHDGTRPKGGRRGRRGCAGRFGPRYGLKIRRRVAAVEARMKQKHVCPVCGR-KAVRRICTGIWQCQKCGATFAGGAYLPVDEGAVPYILNGADVMAAGIVDADENINEGDFVGKAVKNIHHAKDYKYIREAWKCPKK-SYVGELLKKRMIQWRRDPVVKRIERPTRLDRARCLGYQAKQGYVVVRVRVRRGGRKRPRWKGGRKPCKMGMVKYCP-KKCLQWIAEEKAARKFPNLEVLNCYWVGEDGMYKWFEVIMVDPHHPVIKCDPKIAWIAGKAHKGRVFRGLTCAGKRCRGLVEEILHDPGRTAPVARVKFE---DGTKKLIIAPEGVLVGQEIGPEAPIAIGNTLPLAKIPEGTYVYDIEGVPGDGGKYVRAGGTYALPCGELKAFNPMCRATIGVVAGGGRLEKPIVKAGKAYYIAKARNRFWPKPRGVKMNAVNHPHGGKEH-H-IG--RPCTVCR-RAPPGRKVGHIAARRNMGIAAHIDHGKTTLCDNLLAGAGMICE--ELAGKQLVLDFDEQEQARGITINAANVCMVHNYEGND----YLINLIDTPGHVDFGGDVTRAMRAIDGAIIVVDAVEGVMPQTETVLRQALREYVKPVLFINKVDRLIKELKLTPQQMQERFVKVITDVNRLILDMVVKHLPNPLEAQKYRIPHLWRGDINCDVGQAMMNCDPKGPMTMVVTKIILDKHAG-EVATGRVWCGTVKTGQEVYLINC-KRKARIQQVGIYMGPERINMEAVPAGNIVAVTGLRDAMAGETEALHYTCEPVVTVAIEAKNVKDLPKLVEALRQLAKEDPTLHVKIDEETGQHLLCGMGELHLEVKLH-RLKTEWKLDVEVCPPIVVYRECVTKQC-PIVEGK------SPNKHNRFYITVEPGIQYLNEVMDLLVDGFHQAMDEGPLAKEPVMKVIVRLHDAKIHEDNVHRGPAQIYPAIRCAIHCAMMKAGPVLYEPYQKVIINVPYEYMGAVCRELNQRRGQLIDMRQEGEV-MIIIGEAPVAEMFG-FAGAIRGATCGKALWTTEHAGFKRVPDPLANALCHITNCERVGKKEVYIKPACKLIGEVLRVMLENGYIGEFELID-DGI-YRVQLIGK---INKAG-------AIKPRFPVKARDYEK---WEK-RFLP--AFEFGILIVCTCQGVMTHKEALEKGIGGRLIAYVYGAAQIVLAGLPNVGKCCLMRALTPGLV-EGAALGKGMGPQLLC-VIRNADLR-------EERIHCALKDELYELAGIIRVFTKCPGEEPA-YPPFRY-----ARVGADHVLED----GDMATVYDVPGDLLVERVAKALK-EVPEIKPPEWAPFVKTGRHKERLPEQE-D-WWYYRVACVFRKVYIDG-PVGIERLRTWYGGRKN--RG--HAPEHFYKAGGCIIRKALQQLEAAGFVQKVPG--EGRIVTPKGQCFLDKIANAEGLILGRLACKVAGEE-VVIVNAEKAIITGNREDIFAKYK-QRTELRTRTNP-RRGPFYPKRCDEIVRRTVRGMLPW-KTDRGGKACPGPPLGPAIGPLGLNVKQVVDEINKATKEFE--GMQVP-VKIIVEDPKKKTFRIEVGIPPTCQLIKKELGIPK------GCCEAGH-TPAGNLTMEQVIKIAKMKIDQMLAPNLKAAAKEVIGTALCMGVTVEGKDPREVQREIDEGKAGMTHILMIDDCPG-LTKGKEIFVPVTIVEVPPLFVYGIRA-YKQGYLG--LETATEGKELRAGEVLHEGELLDVIAVTKGKGTQGPVKRWGVKVQF-HKAQRAGKGRH-IGNLGP-WHPARVMWTVPQAGQMGFHHRTEFNGFPHYGIVRCDFLMIEGTIPGCFKRIIRVRPAIRG-GIHPKEAAEHHAFCQGPGLGPALRVVATAARALAIKYNKPIVGVNHCIAHVEITKMF------GVKDP-VGLYVCGGNTQVLALEG-GRYRV-FGETLDIGIGNAIDTFARELGIGFP----GGPKIEKLAL------KG--EKYIELPYAVKG-----MDLCFCGVLTETAFAALVEVTERAGGVAANNRLREMLKIM-AEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYRGGRIKLACTNIKALNEVTDQIKQIAERTGVRMCGPIPLPTKRIRITTRKCPDGEGCATFDRFELRVHKRLVDI-EADERAMRQIMRIRV---PEDVTIEIIEFGILCPQEIRKMCAAEITVPDTYDDDGY-PIEGGLMDKRL-GVIDPGLRCETCGARAGEC---PGHFGHIELARPVIHVGFAK----TIHRVLECTCRECPH-------CRDRLEKIPD--KDR----PEWMVLTVLPVPPVTMRPCITLECGIRAEDDLTHKLVDIIRINNRLKCNIEAGAPQLIIEDLWDLLQYHVTTYINNETCGV------PPAKHK-SGRPLKTLAQRLKGKEGRFRGNLCGKRVNFCARTVICPDPMICINEVGVPLAVAMELTVPEKVTEFNYEKLKQRVLNGPEKYP-------GANYVERHLEDGDVVLFNRQPCLHRMCIMAHRVRVMPYRTFRLNLPVCPYNADFDGDEMNLHVPQTEEAQAEAKILMEV-QNHIICPRYGGPLI--AGIQDHICGGYLLTGKTIFCLLLPDGYKRGELEPLPGKTLEETLECKINHAVIMAKTGARGKILNITQMAAMLGQQCIR--------GKRLYRGRVLTHFKPGDL-GARARGFVTNCYKCGLTPQEYFFHAMGGREGLVDTAVRTAQCGYMQRRLINALQDMCDYNLVGVIKVMPTDPDVNLDELE-PIAFGLVALKFYVLGRDEEGYCFDEVADIFRQVENVVKGPKGELQRELKYP-GVQIFTEDGK----VTFKAHINNMIKGVTEGFKYRLKVVYCHFPMTVKVQGDE--VVIENFLGEKNPRRAKIL-P-GVTVKV---KG-SE-IEVEGIDKEAVGQTAANIGIDEAGRGPVIGPMVIAAVDCKKLTPKRREKLFNEIDDIFPVVCAACILAKVTRDRAVEKLKE---EYGGRVRRPLIVVE---NGGVIEYLDAEEGIPACLVPYPEHNAAPRNTYGAGMAKQGLGWAN-FRIRVDTRGHLMHY-PQVPVNCRIMKAVG--FEDRPA--------GQNFVVAYHGYNMEDAVIINKACIERGLARCTFFRTYEAEEKRYLGGD-NFEVP--SPNIQ--GYLGEKYYRHLDE-DGLIFPECKVRFI--EEQCCLGCMV--LQGRRETCRPCEKGVVDKVLVKVTVRDLRGDKFACRHGQKGVIGLIVPQEDMPWTENPHGIPCRMGQLIEAIGG-------KGREIMYDGITGRRLEADIFIGVIYYQRLHHMVADKMHARCRGPVQVLTKQPTEGRAREGGLRFGEMERDVLIGHGAAMLLIERLLEECDKTEVWVCEC--CGYAFKLLLDELKAMVIRPCLDCGLFVEALKGFPGVYGRVDGKIATEPRGCG-GFGFDPIF-IP-------EGFD-RTFAEMTTEEKKTAVARATIREGKGRVRINEIIEP-EIARFTIMEPDIDVKVEGGGFMGQAEAARVAIARLKEKFMKYDRTMLVGDCRRTEPHKPNRCTKGPRAKRQKCYRTKNLVPGQRVYGERIWNPTRCKLLYLGVACGTTACHVCDIVGWEGKVFGVEFCPRVAQPTQAKILIDNGYGM--ICVKC-----RCIDVTKEPEQVFKE-VEKELVFYNPVMCLN--RDDICEEAYGLMKKNDLDPFGCPVEFLDTALRC-VRRNGVLAVTATDTGVLCGAYRNACLRKYLAEPI-RGPLCHEAGLRILIGTVVRYAAKYDLGVE--VLLAYHRDHYFRAFLKLKCGAKKADKCLC-QLGLAGPPGVGKTTTVYALALVRILKRE-------GLEVPKEVLYEIAKRANGDLRAAVNDLDPCLKPYINLDARILPHCHGRYAKKPFGKANVHIVERLINKVMCKKMKAYEVVKEAFMIIERRTKQNPIQVLVKAIENCAPREDTTTIAFGGIRYHMCVDVCPLRRLDIALKNIALGACIKC-YRNKTTYAQALAEEIIAAANKD-PK-SFAYCKKEEIERIAQCCRRG-SHTHGWGCKKKHRGGGCKGGRGMAGTGKRKDQKWT-WTIKYAPD-----RLG--KRGFKILGTGKLTRALVVKAYYVTPKAEEKIKAAGGGYTLDELL------NMCLEEFAKLLPCRQRRCLKR----GIRTHCRDMIVLPEMVGMTIHVYNGKEFVPVEIKEEMIGHYLGEFAMTRKVVQHGCPGVGATRCCMFVAVKADNCGAKVIQIIGVVG-Y-KGTRRRLAAAGVGDMVVATVKKGRPD---MRHQVVRAVVVRQRKEYRRLDGMRVKFEDNAAAIVTPE-GV-PRGTEIRGAIAREAAER-WVRLGCIARIAAELLKCGENRIWI--DPERIEDVAAAITREDIKRLIHDGVIKKKPIKGQCRARARAFQEARK-KGRHRGPGCKKGKKTARM-GKKEVWMMTIRALRKELRKLKAEGK-LDAHTYRRLYIRAKGGQFKNKRQLWEPKTKLGRLVKEGQITDIHEIFRKGYQIKEPEIVDVLL-PEVGRRIRFRVLAAVGNRDGYVGLGIGHGREVGIAIRKAINYAKMNIIEIKRGCGCWECRCRRPHCIPFAVEGKEGCVRVKLMPGPRGLGLVIGDVGKKILTLAGVQDVWCQTLG-----ETRTTVNFAKAVFNALEFLEKELRRAGYGGLDIKKT-PLGTKVTIFAANPGYVIGRGGRRIRELTRILEKQFG-LENPQIEVEEI---KNPYLNAKVQAVRLAQALERGIH-FRRAAYCAIRAIMRN-GARGVEIRLCGKLTG-ERAKCVRFYQGYLAKVGNPAETLVCRGYAQAQLKLGVIGVKVCIMPP--DAKLPDMRKILTPEARERLGRVKLVKPELARQVELLLVQLYQAGQIRERIDDAKLKRILHGGTLDPKVCGVLPVALERATRVVQALLPAGKEYFQGEIIQRPPLRCAVRRLRTRKVYYIDV--LGTYIRCLIHHIGLALGVGAHMAELRRTRCGPFKEDETL-VTLPMEKAVEHLPKVWIRDCAVAAVTHGADLAVPGVAIMTLKDELVPEVERPKRHVPLKEKF-MWTGIALLLYFVLAEIPLYGG--SLLTLGIGPIVTACIIMQLLVGC--EIVRLDLCN-PEDRRFYQATQRQLGL-ACTLLILLDELVCKG-----IGCGICLFIAAGVTIVVFLVVVYLECMRVEIPPIRFMYVCNIPIIFGFL--WVELTGLDA-RCIARQLQNAGLQIPGFRRDPRILERVLQRYIPYVTFWGCFTIALVAVLADFL---GALG-------TGTGILLTVGILYRFYEEIAREQATEMFPFFDEEAILFGR---FILTCGKECYINVKKLCTKPP--L--VIVRKKPKGTGCQ--LEG-EVK--AGDKVLLVEDVTTTGGCVLRAAEVLEREGGEFAGRKLKLKRKKFRWCDIRYKRRVL-RLKEKCDPLEGA------PQARGIVLEKIAVEAKQPNCAMRKVRVQLIKNGKVVTAFTPGDGAINHIDEHDEVIIEGIGGPKG-GCMGDIPGIRYKVVK--VNRVCLKELVKGR----KEKPRRLVPLDQYL-----AAGVHIGTQQK--TKDMKK--FIYRVRQ-DGLYVLDVRKTDERLRVAGKFLAKF--DPECILAVCVRLYGQRPVKKFGEVTGAKAIPGRFLPGTMTNPQVKNFIE--------PDVLIVTDPRADHQALKEAVEIGIPIVALVDTENFLCYVDIAIPTNNKGRKALALIYWILAR-EV---LYNRKQVIVARKDLKLCKGKFAVQVAHGWFHEGQKKVVVKAENLEELFKLKAEAEKLGLPTALIKDAGLTEIPPGTVTVLAIGPGPEEVVDKVTGHLKLKFIFVTGGVVCGLGKGITCACIGMLFKARGFRTTNIKIDPYLNYDAGTMNPYQHGEVFVLDD--------G-----GEVDLDLGNYERFLDTCLCFDHNITTGKVYCAVIEKERKGEYLGATVQVIPHITNEIKERIDVVVVEIGGTVGDIECMPFLEAARQMQIEEGRENVAFVHVTYVPRLRVVGEQKTKPTQHCVKELRCLGIQPDAIVARCEDPLEDCARRKICLFTNVPEEAVICAYDVEDTYEVPLMLEKEGLADCYLCIKEALKHDGIIVPGGFGARGTEGKMMAIRYARENNIPFLGICFGFQLTVVEFARNVLGLEGAHCTEIDPQTPYPVQRDL----DRLGGTMRLGAYPVHIKPNTLARRLY-GREIVYERHRHRWEVNPD-YVEKFEEAG-----LVFC----GIAGDDERRMEILEL--PG--HCYFIATQFHPEFKCRPMRPAPVFRNFTQTVEMAVNLKDVDLRK-PENRFKLEVVLPHGRG-KEPKIAVIADGAVAEAAKKLGLD-VICGEELEELAKCPRQARKLAKKYDFFIAAAPLMPKIGRYL-GRYLGPRNKMPVRIQLKNNPVVHAPIGTEDMDDEKLAENAEAVLNAIINKLERGEN--QVKCVYIKTTMGMGDPKRQ-RKKYET--PCHPWIKERLDRERVLKRNYALK---NKKELWRHETQLKEF-RR--RARRLLYRLGLL---PADAVLDDVLCLTVEDVLERRLQTIVYRKGLARTMKQARQLIVHGHIEVNGQVIRCPGYLVLREEEDTIIIRPLVTEKAVCLIERENKLTFIVDRRATKQDIKRAVEEMFNVKVAKVNTKKAYVKLKPEY--DACEIAARLGVFNLEGEPVEEIEL-PKVFCTPFRPDLIRRAVIACWTHRIQPQGRDPQAGKRRVT------ENIGK--GHGMARVE-R--IKTCP-----RFAAFVPFAVGGRRTHPPKVEKIIWEDINKKERRLAIMCAIAATANYDLVRARGHVVDNVVQI--PLVVTDDLQK-VFKTAQTREIFKKLGVWDDIERAKKNT-KIRAGKGKMRGRRYKKAKGPLIVNHPGVDVVTVDNLGVEYLAPGTHPGRLTIWTKGAARLKTHGETFEILVDPYLARDFK--EGK-D-VPIEEILATPYVFKDAHKGDKACEHEMEKIFGTCDPYEVAKIILRKGEVQLTAEQRRQMLEDKKRYIATVIHRHAVDPR-TGYPHPVDRILRAMEEAGVHIDIFKDAEAQVPQVIKAIRPILPLKLEVKVIAVKIPGDYVGRAYGEVRKFG--NIKREEWGCDGCWMFVI-EIPGGVEEEFYEKLNALTKGIEVIPEGTVIDHIPAGKW--------LKVIEILGLTK-PNGGT--LLIACNVPCKKLG-R-KDIVKVEGRYLCEEEVNKIALIAPMATVNIVKDYKIIEKFNVEIPDEITGI--LKCPNPNCVCN--H-EYVTPRFHVE-SRE-PLKLRCHYCTDINLRRLIRTLRKKCNEEGVKIWKDIAWRLERPRRQRA--EVNICKINRYTKEG-----DVVIVPGCVLGAGRLEHK-VVVAAWKFCEAARRKIIEAGGEA--ICIEELME--RNPKGCGVIIPVRCFTCGKVLADKYYEFKKRV--EAGE---DP-----GKVLDDLGVERYCCRRTLLCHLKPGRYIII------DGEPCRIVNVTVCCPGKHGCAKARIEAVGIFDGKVRCIVKPTCAEVDVPIIDKRVGQIQLMDMETYETGITVEYWET-LGRIQIKYVIYAEFEANGVVDV-----VGAFGQTEGLLGDDL----DLRELQKTGRIGRIA---AALETIDR--------VGPAEARIKVLRIEDVRATKRKYIIERAVPFCDCIIVVEGRAD------VLNLLK--HGIKNAIAGTC--IPETIIKLCKERIV--TAFTDGD--------RGGEL------ILKELLQV-ADVD---YVARAPEGK-EVEELTKKE----IVKALDTVCEC--GVKYIVGARKY-NV-VRRPMRKPRIAKVTINIGVGEC---GERLTKAETMLEQLV-GQKPIRRRAKQTNRDFGIRRGEPIAVKVTLRGEKAYQML-DRLLE--AV---DRK-LKACNFDEHGNFCFGIQEHINIPGVEYDPEIGIFGRIVIAKPPEITAVRP-ITKLCIEDYILIAGAPGEGKTTFAQALAEWYACM-GK-IVKTMEKPRDLQVCE---EITQYTALKG------SMELTGDIL--------LLVRPDYTIFDEMRKTCDFKIYCDLRLAGV-GMIGVVHATKPIDAIQRFIGRVELGMIPQI---VDTVIFIKAGRVAKVLTLEYLVKVPCGMKE--EDLAR-------PV-IEVRDF--ETGELEY-EGRCLKKPCGG-RIILARK-KRKRELGREPANTKVG--EDREKRKIIRTYGGNRKVRLVEALYANVFE--GGKGKKVKILNVVENPANRQYARRNIITKGAIIETEIGKAIVTCRPGQDGVVNAVLAGEIARQVKKEVVDLIKPGAKLYDIAEFVERRIV-ELGGKPA------FP--CNLCINEIAAHYTPYKGDGTVLKEGDYLKLDIGVHVDGYIADTAVTLMEAAREALENAIATVRAGVMIRDVARAIEETIRGKGFNPIVNLCGHKVERYKLHAGVC-VPNGDVFAIEPFAT--TGAGQVIEVPPALILREVRGGMVAQFEHTVIVEKEGAYITTCN-PDKCGHFLCERVCPIQEACCTG--CGICVHKCPFNAITIVNLPEELEEG-CVHRYGINAFVLYRLPV-VKEGMVVGVLGPNGTGKTTAVKILCGQLIPNKPQ-----YVDL---IPKAV--KGK-VRDLLKKADET---G-KFDEVVKELELENILDREIQQLCGGELQRVAIAAALLRNAHFYFFDEPCCYLDIRQRLRIAKTIRRLAE-S---GKNVLTVEHDLALLDYMCDIIHVVYGKP--GAYGIFCQPKCTRNGINEFLRG----YLRDENVRFRFRLEVEGGE-LYVGEVVGIVGPNGIGKTTFVKMLAG--VEKPTE------GY-------KPQYI-KTD---YEGTVFDLLLCGGELQRVAITACLIRDADIYLIDEPCAHLDVEQRLAVCKAIRCLMAKNEKTALIVEH--------D
Thermofilum_pendens_strain_Hrk_5                        GAE-IALAACNPLCT-----QDAWKGMTEREYFECIARAAC-----IEPDITMDDGGDLTVMLHGGTEETTTGVIRLRALEREGKLLYPVIAVNDCMTKYMFDNRFGTGQCTLDGILRATNILLAGKNVVVAGYGW-VGRGIAWRARGMGAR-VIVVEPIKALEAYYEGFYVT-DMREADVFITATGNRDVVREEHFLEMRDGAILANAGHFNVEICVEDLERI-STCKRRINEN-VEE--------YTLRN-GKKLYLLCEGRLVNLAA--AEGHPCEVMDLCFGNQVYRLPAQLDRRIALIKLKCLGVRIERLTPKQVEYLRCWDIGDLEEAKQKIREMVE-LPLRHPELFKRLGIDPPKGILLYGPPGTGKTLLAKAVANET-----DAYFIAINGPEIMCKFYGECEQRLREIFEEAKEHAP------AIIFIDEIDAIAPKREEVTGEVEKRVVAQLLALMDGLEARG------DVIVIGATNRPNALDPALRRPGRFDREIEIGIPDKRGRLEIFGADIAALCREAAMKALRGPPGTGKTLLAKA---VATECEANFVCIKGP--EVYCKWVDEIDALAPMRGLVTCDCGVTERVVCQLLTEMDG--LERLEGVVVIAATNRPDIIDPALLRPGRFDRGIAWIYACYNNTIIHITDLCGAETIAFACGGMVAKADRDKPCPWAAMQAAARAAKIALDKGIRVVHVKIKAPGGY-GPKTPGPGAGPAIRALVRAGLMVDRIEDVTPLPTDCIRKPGGRRGRRGPAGRFGARYGATLRKKVAAIERKMKARHKCPRCQAVGTVKRECIGIWVCRKCGYKFAGGAWLPVDCGAVPRILNGADVMVPGIKKIDGEFKPGDRVGKAVRNIHYLGDYKYMAEIWKRPFK-GEHGQLMRERFMLWRREPTVVRIPRPTRINRARALGYKAKQGYIVARVRVRKGGLNRPRPCCGRRPKRMGVYGYCP-HKCAQQIAEERAARKFPNLVVLGCYYVGEDGVYKWYEVVMVDPHHPAVKRDIERRWVAGFKKKAGV--------KVTRDLVKDLLHEPGRGAPLALVEFE---DGTKMYMIPPEGLAVGQKIGAKAPAVLGCIVEIGNVPEGTIVCNIEIRPGDGGKLARCCGAYALPCKKVKEVCCEARATIGMVAAGGRIEKPMLKAGKMWHWCRAKCFKYPTVRGKAMCAYAHPAGGGHHPK-GL--TP--APR-NAPPGRKVGHIAPRRNIGTLAHVDHGKTTTCDCLLMGAGILCP--KAAGQALALDYVEIEQLRQMTVKAANVCLYHEWEGKP----YVINLVDTPGHVDFTGHVTRCLRMMDGGIVVVDAVEGVMTQTETVVRQALCEYVRPLLYINKVDRLIKELRLEPREIQQRFVEIVKEFNALILDMVVEHIPNPREAQKYRVPKLWKGDLNCEIGKAMLECDPDGPTVVAVCKITVDPHAG-HVATGRVFCGTVTEGQEVYLLNA-KDCAKVLQVGLYMGPYREKTEQICAGNIVAMLGLDKARAGETEHLAYVAEPVVTIAVEPKKCCDLPKLVDVLRKLAIEDPTLKVYINQETGEYLLCGVGTLHLEITLW-ELKQRTGIEIVTCPPIVRYRETVREKG-QVFEGK------SPNKHNKLYFYVEPGIQYLREVKDTIIQGFRWTMEAGPLAQEPVRGVKVVLVDAVLHEDPAHRGPAQIMPATKNCIMACLLCAKPTLLEPILKVDVKVPTQHVCGVLTVLNRHRGRILCMEERGMV-MRVLAELPVAECFN-IADEMREATQGRAFFAYEFYKWAPVPDTLANALCTIMNNEVRGKKQCVIYPCCKLIVAVLDTLKRCGYIGDFELID-DGK-IVVNLLGR---INKIG-------VIKPRYPVKKNEFEA---WER-EYLP--SRDVGLLIVCTPKGVMTHREAKEKGLGGVLLAYVYGDVQVVLIGCLGCGKTCLFRCLTPGFL------GFTDPGRLMA-LARNADLR-------EYNVYHAIATYIFRELDLIRVYTRNPKTGNVEKRPFRY-----AKVGKDFVLED----GDMVNAKFVPPRLLIEELAAYLKENVKEIQPPEWALYAKTGPTRERPPQDP-D-WWYKRCAALLRKIYLEG-PVGLERLRTAYGGRTK--NT--VKRKHFKKAGGCAIRKALQQLECAGLVAKTPR---GRVITEKGRALVDTTADGTGHIAGRLACVVAGDR-VVVVNAEKIVITGKPKRVVEKYLKRWVEWKTYYNPELRGPKYPKTPDRLFKRMVRGMLPM-EKTIGGKATAGPPIGPALGPLGLNVMQVVKRINELTADYA--GMRVP-VKVTV-DVEKKTFEVEVGTPTTAALIIKELKVEK------GAHQPCR-ENVGNLTLQQVIKIAKIKKKDMGACTLKAAVKTVAGTAQCMGVTIEGKPPKVFIEEVEKGKVGMLHVIGVEMNKNCPFYGQERFYAATVIEVPPLKVVAVRV-YEKTPYG--KKTLCEGKDLTICDVFKEGDYIDVIAVTKGKGFQGCVKRFGVEEMP-RWHKHRKGHCR-IGCVGP-QKPA-IMFYTPFPGQLGFHQRTEYNGWPHYGLVRCQFIIVEGCVPGAVKRLVRLRHAIRG-GIKPTEAAEHHAVALGPGMGPCLRVGATLARYLALKFGKPLVPVNHAIAHLEICRLTT-----GLEDP-VFVYVAGGNTMVTTFNE-GRYRV-FGETLDIPLGNCLDTFAREVGLGFP----GVPRVEELAL------KG--REYIPLPYTVKG-----QDVCYCGLLTETAYCMLVEVAERAGGVARCRILLEKLRRM-VEDRGGVLGVVPPEYAGDNGAMIAYTGALAFCHGRIRLCCTNIEDLNAVCEEIRQIAQKTGVKMRGPIPLPVKRMRVVTRRAPCGQGYETFDRFELRIHKRLIDL-DADERATRLLLRTRV---PPTVRVEIIKFGILCPEMIRKIAVLRIETCELYDEEGF-PIPGGLMDRRM-GCIEPGAVCQTCGNRFTNC---PGHFGYIELARPVIHPCFAP----YIAILLKATCNRCPH-------CWERLCRIPE--GDR----PEWMVLRVIPVVPPCVRPCITLECGDRCEDDLTHKLVDIIRVNQRLKENIDAGCPCLVIEDLWNLLQFHVATYFDNELPGI------PPARHR-SGRPLRTLAQRLKGKEGRFRGCLAGKRVDFCCRTVICPDPNLCINEVGVPIDVAKVLTVPEKVTPWNIEKLRKLVINGPDVWP-------GANYVERHLMDGDVVLFNRQPCLHRICIMAHIVKVLPYKTFRLNLLVTPYNADFDGDEMNLHVPQCEEARAEARELMLV-QEHIMTPRYGAPII--GGLHDYICGCYLLTGKQIVCMFLPDGYECGELQPMPGKTRKETLEDLINHAVIMAKTGARGCMLNLTQMAAVVGQQCVR--------GKRIERGRALPHFVKGDL-SPLAKGFVYCCFRRGLCPVEFFFHAICGREGLVDTAVRTAQCGYMYRRLQCAMQDMCK--VAVLLRVLPDDAETKPEELE-PIAFGLEALRMVILMPEETEGGTEELETIIQCVQGVVEGPLGKVEKDFCHARRICIRVEGNC----VTIACIINNMIIGVTKGYRYKLKIVYAHFPMCLKVEKDK--IIIENFLGERGKRIAGIM-P-GAKVKI---EK-DD-VIVEGIDLDAVAQTAANIGIDEAGRGPMLGPMVVAIVDCKALCPRRRLLLCRAIDEKYTIVGAACIVAKETRDEIINALKK---TYGGRIRRPLIVVE---NGGIVEYLDAEEGIIAMTIPFIEYNQCPRNCYQAAMAKQGIPHYN-FKLRMDPRMHVMYY-PQKPVKTRIFDLLP--LDNLPY--------GTNMVVAGGGYNIQDAVVINKAAIERGMCRCVFFRTYEAEERRYPGGD-RFEKPCLEKDLL--DVKPPQAYEAIDPVDGIAYVEAELRFY--TCTLEP--RV--MTKRKDTCRHGEKGIIDRVLAKVRVRDLRGDKFACRHGQKGVVGMLVPQEDMPFTENPHAIPCRMGQLLEAITG-------KGKEVLYDGVTGEKLEAEIFIGVVYYEKLHHLVADKMHARARGRVQILTRQPTEGRAREGGLRFGEMEKDCLVGHGACMLLRERLLECCDKTTIWVCEN--CGYAFKLLLQELTGLGLCVRLDAGLFVKALNGFPGPYGEAAGVITEEERGTG-GFGFDPVF-RP-------RGCE-KTFAEMTTEEKKTARARVILRDGRGRVFVNEILEP-EVIRLKIMEPDIYAEAEGGGIVCQACAIRTAIARLKKLYLAYDRRLLVEDPRQAEPKK--PRGRCARAKRQKCYRTVNLAPGVKVYDERTWNPYRCKLLYLGVACGTTPCHVCDIIGPKGVLFGVEFAPRIAQPFQAKYVADNGYIM--MAIKA-----MCIDVTATPCETYKR-EITHLVFYNPRMRCC--RDDINPRAVEIIRQNDLDPFGCPAEYVDPALRC-LKHKGLLCVTATDLPPLLGKYPKTCVRKYFCKCI-ETEFCRELAVRILLYFIAREAAKLGRTIV--PLYCYYMEHHVRVCVLVLKTECRYGGLTD-SIGLYGPPGCGKTCIVHATALENICCKE-------GVECCREVLCAIADNAKGDLRAAINDLDPGLKKYICLKPVLVPHCEGRHAKKRFAKARVCIVERLANNLMGKKMLALNIVKRAFEIIELKTGKNPIQVLVWAIENACPREETTRVIYGGILYHVCVDVCPQRRVDLALRFITEGARACA-FNNPKPIEECLADEIVAAAYGD-PN-SYALRKKEEVERVALAARRG-SRTHGWGRVGQHRKCGCRGGRGLVGY---HKHKWC-WTVKYAPD-----WYG--KHGFKLTGCGQVRNKIIVKVPVATKRAICKIEAQGGGYTLEELR------QMPIEKLAEIMPARQRRCLLRVFKQGIKTHLRDFIILPEMVGLTIHVHNGKEFVPVEITPEKIGHYLGEFALTTKKVEHGEPGLKATRCCMFVALKADNCGATLAKVIGVPH-Y-KAVWRRIPGAAVGDIVIVCIRAGKPE---LRKQVMRAIVIRQRRPYRRPDGCWIAFEDNAVVIITPE-GE-PKGTEIRGPLAKEAAER-WPKLCAMARLACEVLGVGECRIWI--DPDKLDEVCAAICRCDVRRLIKDGVIRVLPPCTPCRGRVRERRLKRK-KGRGRGPGCKKG---PRV-DEKRAWINRVRAQRRYLKFLKEKGQ-IDTKTFRYLYRLVKGGMFRCLCHLWQPRTLLGRLVVEGKIKCIDEVFARNMPIREVEIIDTLL-PGLGEVCQYQVTVAVGNEDGYVGVGMGKCRQIGIAIEKATRRAKLNIVPVRRGCGCWECLCGEPHCIPFKVEGKAGCVKIELIPAPKGVGLVACDVAKTVLRLAGIKDVWCRCYG-----ETRTTHNMAKAVYEALEYLQRQLVRANYVHAQFFKT-PIGTKVIVYAGVPGLVIGRKGANIKAIAEVLEREFG-IENPQIDVVEV---PNQDLNAKIMAYRVARALVRGVR-FRRAALVALNRIMAA-GARGAEIVICGKLTC-QRHRTEKFTRGYVPKCGEPGEELVDEAIVHVLLKLGMYGVKVRIMKP--A-KMPDLRRILTPEARARLCNLKLVKPELVEALEIQLIQLAECRCVRVPIDDETLKQILHAGTLDPKVCGVLPITLNNAVRVLPVLLKEDKEYFKGRIYQRPPLRCAVREVRIRQIYDIRL--LGTYMRKLCHDIGEILGVGAHMQELRRIRCGCLYEDRNC-STMPVEAAIQHLPKVWIRDCAVDAVCHGAPLAVPGVAILTLKGELVPEIEKPRRKPPLCERL-LWTALVLVAYFVMGQTPLYGG--TLIELGIGPIVTCGIVWELLVGC--RIVNLDLTT-PEGRRTFAGLQKQLFV-ACTFVILMNDMLEKG-----IGCAVCLFIAAGVMVVMLLLLTYMECMKITIPPLKFLYVCVMPVIFGVA--WILTCGMDP-ETQAEQLAKAQLQIPGFRKCEKVIACMLKRYIWGLTILCCIIIGVIAVVCDIF---RVMG-------GGTGILLLVGIIVQYYCILACERALEMYPLWEIGAVKTGE---FRLTCGKVCYIDLRKLPCHPP--L--IYARREKKGTMKQ--LEG-DYA--RGMKVLLVDDVATTGGTLLDIARLLKCEGGMFAARKLELKRKKFRWCDLEYKRRIL-QLKKKVDPLEGA------PQARGIVVEKVGIECRQPNCAVRKVRVQLLKNGKVVTAFLPGDGALLFVNEHDEVVIEGIGGPEG-RAYGDLPGVRWKVIK--VNGVCLKEILRGR----KQKPTRLIPLEMYL-----AAGIRIGTKMK--SKFMEP--FIYCARP-DGLYLLDVKKTDERIRIAAKMIARY--DPCKFVVVCGRQYGHRPVRKFCGLVGCKPMLGRVLPGTFTNPALCHFTE--------ADLMMVTDPRVDEQAVVEAGTMGIPVIALCDTDCPICNVDLIIPTNNRGRKALALIFWLLAR-EV---LRIRKQVIVLRRDLDMGKGKMVAQGCHAWVEEGQRKIVVRVDCEEELLCVYRKALELGLVAVLVEDKGLTQLPPGTPTAVGIGPADEEIIDKVTGHLKLRYVFVTGGVVCGLGKGAVAACIGKLMQLRGFKVDMIKIDPYLNVDPGTLNPVEHGEVFVCEEVWEFEPAPGYRFTIAEIDQDFGTYERFLDVNMHPCNNITCGQVYLCVILKERMGEYLGRTIQVIPHVTEEIKRRIDVLVVEVGGTVGDIEAMPFLEAIRQFRLEYPPGYTALVHVTLVPYLCCLGQLKTKPTQHCVKELQCMGLQPDVVIGRCDRPLPEDIRRKIALYCCVPLEAVFCDPDLECVYLLPVVLEEQGIQDCYICINEALCHHGILLTPGFGCRGVEGMIQAARYALDTGKPFLGICFGAQLLFVAFMRYRVGLAGAHCTEIDPETPHPVQKGV----AFKGGTMRLGAHPVKVVPGTRLFEAY-KCELIYERFRHRYHINPA-YRELAERHG-----LVVC----STD-PCGRIINCIEV--AG--DAWIVGVQFHPEFKCRPARPCPVYRRFTQCVEMIVTLRDVDVKK-PENRLNTVVALPHPAPGKLAKVAVIACGDTALKAKEAGADIVVDKDELQKIGNDKKAAKKLAKRYDFFLAQPDLMPLVGRVL-GKYLGPRGKMPVRIRMKDEPQIACRIGVETQPVEHLAENARAVLAEILKKFPPP----NIDRIYFKLTMGMGDPKKP-RKKWQG--PCHPWRKETLLEEMQLVGEYGLR---NKRELWIAKCLLREI-RA--KARKLLYKMGLL--PCEDACLDDVLCLTVRDVLERRLQTIVYRKGLATTIRHARQLITHGHIAVNCRRVRCPGYLVCRDEENFIIVKPYLTEKTLRLMEETNTLVFIVDRRACKPEIKRAVEALYNVKVAKVNTKKAYVKLCKEY--SAADVACRIGVYDLNGAAVERIKL-PCFFKCPVRPDLIRRVYIALFTCRLQPKGTDPLAGLRTTA------ECLGV--GHGIARVA-R--IKGGL-----R-AARVVQAVKGRRAHPPRVEKIIREEVNRKEKRKALLCALAAVACRDFVLKRGHVVPDIP-L--PVVVADDLEC-ICKARDLRAFLEKLGLWKDVERAQTNT-RVRAGKGKMRGRRYKKPKCLLIVNMPGVDVVTYKELCVLHLAPGGNPGRLTVFTKCAARLERGGKRYEIIVDVEKAWLYK--NGE-K-LNVREIMEGEFIYYDANRGLKACECELKKVFGTDNIYCVAEIILKQGELLLTTEQRRELIEQKKRQIIELICRNAVDPR-TNAPIPAKRIELALEEARVCIDPFKPAELQVPDVIKALRMTLPMKIMKAIMAVYIPAAYVGKAYHAVCKMG--KVLRENYRCDGCLDLEI-EVPAGLQCCIVEKVACLTKGVRKIREGTVIDHIPAGRA--------LNVLKILGLTG-REGLT--IAVVMNVPCRKLG-V-KDIVKVEKRFLEPCEVDKIALIAPCATINIIRDFQVACKRRVEPPAVVTGI--LRCPNPNCVTNCER-EPVTPRFVRV-SLC-PLKLKCAYCTNIHLRLLIHKLRKYCRLYKAPVWRDVAEYLERPRRKRV--EVNLCRIDRHIKEG-----DVVVVPGKVLGGGCITKCNVVIAAWRFCRCALERLD---GRVKAICIEELLE--QNPEGKNVKIPIRCFTCGALIGDKWNEYCTRV--ANGE---DP-----NKVLDDLGITRYCCRRMFLCHIKVGCFIVI------DGEPCKVVEVEKCKTGKHGCAKARIVGIGFFDGGKRCIVVPTDARVEVPIIKKFTAQVQLMNLEDYCTGVEVEVWEV-MGRHKIKYVIKAKMEIKGCVDI-----IGAFGQAEGLLGCEL----DLRELQKTGRVGRIA---ATIECIDK--------VGPYPAKTEVVCIEDVRAEKRQKIIERAVETCDTVILVEGRAD------VQNLLR--HGYKNVIAGAT--IPKCIKCLVENKKV--ILFVDGD--------RGGEL------IARNVINA-LKVD---FVARAPPGR-EVEDLTAKE----IARALDVAYTK--GLKCLIGVRIG-EI-IRKPMRRVFIGKVVVNIGVGEG---GERLMKAAKLLEELT-GQKPCLRPAKKTVREFGVKKGENIGVMVTLRGEKAINFL-KKALA--AV---DYK-IHEKCIDRHGNVAFGVKEHILIPGVKYDPEVGIFGRIVITKPPEITATRP-VARLRLEDYILIAGAPGMGKTTFAQALAEYYYRK-GK-VVKTIECPRDMHLPA---DITQYCRNYA------TCEEIHDVL--------LLCRPDYTFFDEMRDTKDFELYADLRLAGV-GMVGVVHATCPIDAVQRFIGRVELGMIPCI---IDTVIYVKHGRVEKVYCLETTVKIPHGLKE--EDLAR-------PV-VVVRDF--MTGEPEY-EGNDLRKITGG-IKGRHVKTKRKYLCGRYPILTVPG--QAT-EVKVVKARGNTYKLKVKVACEVNVYIPKEGKTVRAQIIKVLDNPCNKDFARRGIICKGAILQTCVGKVKVTCRPGQDGVVNGVLAGDVAREALKLAVDICHEGVPLIEIAERVEEFIR-SRGALPA------FP--VNLCINQVAAHYTPCCNDELRVPKGCVLKIDVGVHVDGYIADCAVTLALAAFEALKCAALALKPRCTAYDVGKVVEGAIRKYGYKPIENLTGHKIERYNLHAGKC-IPNGEVYAVEPFAT--NGVGQVIDCGWCNILVEAGGGLVCQFEDTFIVDQDCAKPIVCR-PCKCN-QECVKFCPICEELCVG--CGICVKKCPFCAICIVNLPEKLAED-LVHRYGPNGFELFRLPV-PKEGRCLGILGCNGVGKCTCLKILAGITRPNKPQ-----AVDA---LAKVT--L-S-VGEALKKVDEK---G-VAREVAEELGLLHLWDRPVKALCGGEMQKVAIAATIVKDANVFLIDEPCCYLDVKERLRVADAIRRLAR-P---GVYLVVVEHDLAVLDYVCDLVCIIYGEP--GVYGVVGTVKGVRAGINTYIDG----YLREENVRFRFCLEVCAGE-IHKGEVIGILGPNGIGKTTFVKILAG--ILEPDA------GY-------KPQFLGEVK---VAGTVREFLLCGGELQRVLIVAALGREADLYLLDEPMAYLDVEQRYAVCRVIRRLTAEKGVATFVVEH--------D
Thermoplasma_volcanium_GSS1                             GAN-VRMACCNPLCC-----DDARKGETQEEYYENLQRTLE-----KPPDIIIDDGGDLTKLVHGGNEETTTGVVRLKAMEKAGVLLFPMFDVNDANMKHLFDNRYGTGQCTLDGIMNCTNLLIAGRNVVVAGYGY-CGRGIAMRLKGMGAN-VIVTEPIKANEAIMDGFQVR-RMNDADMVITATGMKDVVKYEDALVAKKNIVLANAGHFDNEVAVKEIEKH-SLEKREVREF-VKR--------YRLEN-GNTVDVIADGRLVNLAA--GQGHPVEIMDLCFALQVYPVPPEIDRYVAEIRLKQFGGELDTLTEDQIKYLNCWDIGGLCEQLGKIREMIE-LPLKHPELFERLGITPPKGVILYGPPGTGKTLIARAVANEC-----GANFLCINGPEIMCKYYGQCEQKLREIFCKAEETAP------SIIFIDEIDCIAPKREEVQGEVERRVVAQLLTLMDGMKERG------HVIVIGATNRIDAVDPALRRPGRFDREIEIGVPDRNGRKEILGADLAALVRECAMNALRGPPGVGKTLLAKA---VATECNANFICIKGP--EVLCKWVDEIDCIAPRRGTT-SDCGVTERIVNQLLTCLDG--IEVMNGVVAIGATNRPDIMDPALLRAGRFDKGIAHIYACQNNTIIHVTDPTGAETIAMVCGGMVVKNDRDQACPYAAMKAADMVCETLKEHEITDLIIKVRAPGGN-KCKIPGPGAQAAIRALCRAGLKIVRIEEVTPIPHDGTKKKGGKRGRRGAAGRFGPRYGVTIRKEWNEIYKQKIALYTCPCCKK-KRVKRLAAGIWVCRHCGYKFAGGAYNPVDAGAEPHIINGCNVFAQGILCIDCCIKKGDIVGLAVRLIHHPDDYQEIREEWKCLKK-SEIYDVEKCRMIGWRHGPCVVRLDHPTRIDRARALGYKCKDGFIVVRCRVRRGGCNREKIMGGRRPRRLAYNKLTR-KKCLKLIAEERAADKYPNLEVLNCYYVGEDGLYKYYEVILVDKCHPNIYNDPHICWICEPQNTGRVYRGLTCAGYKVRGLVKDIIHAPGRNCPLLELVDC---TGKKVYQIAFTGAYVGQKIGNVDTINPGTTTVLANIPDGCYVYNIECCPGDGGEFCRCAGTFALPCGCMRDFDPRCRATVGVVAACGIIDAPILKAGTHVHYLRCKAKRPYTVRGVAMNAVNHPHGGGNHQH-VG--RPCTVGR-NAPPGRKVGRLCPKRNIGIVAHIDHGKTTLCDNLIAGAGMMCE--ELAGKQLVLDYDEQEQARGITINAAVACMVHAFQGKE----YLINLIDTPGHVDFGGDVTRAMRAVDGVIVVVDCVEGVMPQTETVIRQALREYVKPVLFINKIDRLINELRLNCDEMQKRFTKIICDVNKLILNMVIRHLPDPKTAQCYRIKQIWKGDLETEVGKCMVCCDFKGPVAMMVTKIIIDPHAG-EIAIGRLFCGTVKKGTDLYICGD-GK-GKVQTLAMMVGPDRIPVEEVTAGNIAAIVGLKGAIAGCTEPMIHYCEPVVTLAIEAKHTADLPRLIDVLRDICKADPCIQVDINQETGEHLICGMGELHLDVTLY-RIKNDYKIEVETCEPIVVYRETVEKKG-GPFEGK------SPNKHNRFYFEVEPGIQYLDETMELLIEAFTEVMNRGPLANEKVFGVKARLVDAKLHEDCIHRGPAQVIPAGRNCIYGAMCEAKRILLEPVQKVFINVPQEEMGCAINEVQQRRGVIEDMTQEGEE-VCLVARIPVCGMFG-FACAIRCATGGKVLWCFENAGYQKVPDTLNDVINCIKNACRLGRREIIAEPAAKLIGKVLKVMQDYNYIKCFEVID-EGK-FKIVLNTT---INNCG-------VIKPRFPVKNENLEK---YEC-RYLP--AEDFGILILTTTKGVMCNIEARKLGIGGKLLAYVYGDATVALVGFPNVGKCCLLNVLTPGII-ENACYGAGRGREILC-TVRCADMK-------EFKLVNALREGIYRCLKLLRVYLRNKAGVVDFDKPFRY-----AIIGIDYPLLD----EDMVCVKYVPCDMLINYVCGKLK-EEKKIKEPNWVKFVKTGVCKEKPPLQD-D-WIYVRAACMLRKLYING-YLGICRMCCEYGGKVD--RG--SKRYHAACGCRCITRFLFHELECAGLVQKTQK---GRCLCPQGMCLLDNACDACNTVYGRLCAYVAGEE-VVIVNACKAVITGDRKFIIDKFK-QRLDIGC----VRKGPYYPKTPENILRRCIGDMLPK-KITRGGKATTGPPIGPALGPLGLNVAQVVKEINEKTKEFQ--GMQVP-VTVTVIDPETKKYEITVGVPPTCALLKKELGLEK------GACKKKE-AVAGNATLEQIKNVAIKKMPCMLAKDLKCAVLEVLGTCVAMGINVEGKDPKEVQKLIKCGKVGMTHVEMVDYRKTCVTAGQPIFVPVTVIEVPPLDVIGIRL-YDEDEEGN-MVVVYEGKTIRFEDFCKPGKFVDVLCVTKGKGFTGHVQRFGVKLLP-RKNRK---HRRMIGTLGP-WHPDWVRNTVPQAGQMGYQQRTICNGFLHYGLVKNDYVLLFGCVPGPAKRLIKMRDPARG-GIHPTQAAAHHAFCMGPGLGPCLRVTCTAARTLAVTLKRPIIGVNHPLGHIEIGKRLC-----GAQDP-VMLYVCGGNTQVIAHLN-GRYRV-LGETLDIGIGNMIDKFARYAGIPFP----GGPEIEKLAK------DG--RKLLTLPYCVKG-----MDTCFCGILTETAFCMLVEVLERAGGVALNNRLREMVCEM-GREVDATTYMTDKNYCMDNGAMIAQAGLLMYKCGRICLCGTEHKIVDMVCCEIKEIACRTGVEIHGPMPLPTKKLVVPVRKCPDGEGTNTWDHWEMRIHKRLIDV-DADERTLRQLMRIPI---PDGVQIEIIKFALLCPDEIRKLCQVKVITADTYDDDGY-PIEHGLMDLHM-GVIEPGLRCATCGGKVDEC---PGHFGHIELAMPVVHVGFVK----EIKMFLDATCKCCPH-------CRERLERIPD--DDR----PEWMILTVLPVPPINVRPCITLETGERCEDDLTHKLVDIIRICQRLRECRDNGCPQLIIEDLWDLLQFHVTTYFDNQTPGI------PPARHR-SGRALKTLVQRLKGKEGRFRCNLCGKRVNFCCRTVICPEPYLCVNEVGVPEKAARELTVPVIVNQFNIDEMREFIKRGRNPRDKYGKYMAGVNYVERQLMEGDIVLFNRQPCLHRMCMMGHTVRVLPGQTFRFNLAVCPYNADFDGDEMNLHVIQKEEARAEARIIMKV-QEQIMCPRFGRPII--GGIHDHVTAMFLLTGRNIFCTILPDGYKRGELQPAPGRCVEDTLEIEIVPCVIMARCGARATMLNICEVAGIVGQQCVR--------GGRLNRGRTLPHFKRGDI-GADARGFVKCCYMTGLTPTEYFFHCIGGREGLVDTAVRTCRCGYMQRRLINAFEDMAD--VLVCFKLLPCDCDVDTCVMK-DIGFGLKYIHLEVIVEDKE-GEVDRIEKVLCMVKGVMTFGNKKLEKKFADN-YVRLLVEDNK----ITWACEICNMVKGLKEGFQYEMKIDYCHFPMRVCVKGKT--VVIENFFGERCPRTAEIV-G-ETQVCV---KG-DR-LFLNGPCKKDVGETAANIGIDEAGRGPVIGPMVICIVDCKMLCRKRREYLFDKIDCIYPAVCAACIVCKVIRDREIDKIAE---KYGGRLRRPLLVLK---DGGALEWLDAEEGVVACIIPYPEHNCCPRITIACAMAKQGFAQCN-VRIRPDTRGHLLHY-PQVPVRTRVMEYTH--YDRRPA--------GQNFVVAYEGYNIQDALVINKAAIDRGLGRCTFFRTYCAEERRYPGGD-KFEIP--THDVI--GARAEEYYKNLDE-SGIIYPEAYVRFL--EEGEER--LG--PQRRRECCRPNECGYVDNVVVKIKVRCERGDKFACRHGQKGVIGLVVPQEDMPFTENPHCIPCRMGHILEMIGG-------KGTEVMYDGITGRKFRADIFVGVIYYQKLHHMVAGKFHARCRGPVQILTRQPTEGRCRQGGLRFGEMERDTLIAHGAAMVIKDRLLDQCDGTVLYVCGNPCCGYAFKLMRDELICLGVVMRLDTGLYIECLNGFPGPYGKVIGEICKEIRGKN-GFGYDPIF-IP-------NGCE-RTFAEMETCEKKTAVARAVVKKGKGIITINELYPV-EVLRNKILEPDVTVKVKGGGVTGQADACRTAIARLENLFRQYDRTLIVNDVRIKLPKK--PGGRGARAKKQKCYRTETETP-QRVYGEREWDPRRCKPLYLGACTGTTICHICDIC-PAGTIYGVEVCYEICQRNQIQIFKNNGFLV--LKI-------RCVKCTEDCRCILNT-AMDQLGFYNADQVLN--RDEICPCCCEIIKQNDVDPYGCPVPYLDAAIMN-VRKGGYLGITATDQCTLTGCTLNKTRRRYGAYIV-NDIYRHEMGIRTLIGYIARRAAAFDRYIE--PQLCIWNHHYYRVFVKVGKGVNGADKMIE-NIGLYGVQGCGKTCAAYAIAIKWIINQE-------GFCLPDDIINCIIDKNAPDIRCIINDVDPGMVKYINVKCALNLHTGGRFCCYYAGKINMNVVERLINKLMGKKYCAYKITKDAFDIIADKTKQNPLQILINAIENAGPREEVTRLKYGGIAVPKCVDVCPCRRVDEALRNIATGATNAC-FKCKKCIVNCLADEIMLAAKND-AC-SFAICKKEEIERVAQCARRG-GHY--GRGMKAGRGKGKKGGRGNAGM---GKHKWI-WMVKYDPL-----HFG--GKGFKLLGCGNFCVKCRIIIDKATEKAICKLCAIGCGYTLEQLQ------EMCLEELIKILPARARRCLCR----EIKTHVRDVIILPCYVGKIVEVYNGNCYCKFEIKPEMIGHYLGEFVMTRKEVKHCGPGVGATRCCKFMPLKADNTGARCICLIDVKA-Y-HGKARRIPAAGVGDMFIACVKKGTPE---MRCKVVYAVVIRQKRPYRRPDGTMVEFEDNAAVLVTPD-GE-VRGCEIKGPVAREAAER-WPRIAAIARIVCDLKGVGTCRVYI--DTNKLDKIDEAATRCDILALIEQDVVKIKQKKGICNGRLKKRIKQLC-KDRRRGPGCLRGTRNARY-KRKERWIDTIRALRDELRKLKKDGK-IDPAVYRKYYRIIKCGCIKCRAQLWTPRTQLGKLVACGQIKTICEALKTKLPLKEYEIVDYLL-PNIGRRMTYCITVVVGNEDGYIGLGIGRCKEAAPAIRKALINAKLNIMEIRRGCGCWECGCGRAHTLPFLVEGKCGCVRITLKPAPRGVGLAVGNVAKIILRMAGIEDAWGFAAG-----HTKTTVNYALAVYNALEYLVKETENAGFGKMCMKRT-PFGTNITLYVNRPGLVIGRRGCKVQQMTETLEKKYA-IETPQIEVKDV---KDPDLNPCVIAKKIALCLEKGWC-YRKAGNTCLKRTIDA-GARGVLIKICGKICG-ERARYQKFIYGNVKYCGEPGCKGMLVGFCTAKLKVGILGVTVKILNP--EYKLPDLRQILDPCARERLNNVRLVRPDLADNVENQLIQLACMGRINRIIKECDIIDILHIGTLDPNVTGVLVMAIGKAVRLIDVVHEKPKEYFTTRIYQLPPVRCAVRKVRIKTIYELDM--IGTYIRTLCTDIGYVCGKGGQMVDLRRICTGPFKEDIA--ITLDMTYAFIDYPKIVAKKCAVENIAHGCDLYVGGVCVLCEDNELLPAVKKAKGHVEFKYKM-LWTAVIVILYFALCNIYIYGG--SLMDLGIGPIVTACIVMQLFVGA--KIFNLDLQN-SEDKAIYQGVQKQLFF-GCYLVFLMDEVVCKG-----IGCGICLFIAADVTLLIFFLVAYFQCCKIELPPLQLLYACNIPVIFAIF--WIETTNMGA-SAVAKQIQCCGMQIPGFRRDPRVMERVLKKYIPAITIFCGAAVGLLAAGANLI---GTVGDT-----SGTGLLLAVGIIIQFYEAMGREQLMEMHPLVKCGAIKFGD---FILTCGKRCYVDIKEAATDPP--Y--VIVRKE-RGTLCL--IVG-RLN--RGEEVDVIEDVVTTGNCVLKAINVLRENGGLNAGRKLLENRKKFRWCDRDYKRRVL-QLKRKCDPLEGA------PQAKGIAIEKVGIEAKQPNCAIRKVKVQLIKNGRQITAFAVGDGAINYIDEHDEVTVEGIGGRMG-RCKGDIPGVRYKVVA--VNGICLKELVKGR----KEKTVRLIPEEEYQ-----KCGVHIGTQVK--SCDMKP--YIFKIRN-DGLYILDVKKTNCKLIAAGKMLARF--DPQDILVVAQRQYAFRPVAKFAEVTGAVCITGRFNPGTLTNPCLKFYKE--------VKVIVVTDPLADVQAMKEAIKIGIPIIALCDANNKTDFVDLVIPTNNKGRRCLAVIYWLLAR-EI---LKNRKLVVAVRKDLDMGKGKIAAQVAHAWMDEGQKKIVVKVPNVDEIYIIKKKADCMGIINEVIQDRGYTQVEPGTVTCIGLGPDYEVYLDDITGKYKLQYIVVTGGVICGLGKGTITCCIGHILKDCGFKVCCVKIDPYINYDAGTMNPYQHGEVFVLDD--------G-----SEVDLDLGNYERFMDINLCWKNNITTGKVYLEVIEKERHGDYLGKTVQIIPHITDEIKRRIDFVLIEVGGTVGDIECMPFLEAVRQLKREE--NNVIFAHVTLVPEIGPTEEQKTKPTQHCVKALREIGIQPDIIFARCKNRLLEETKKRICLFTDVPEGGIICVYDVENVYLLPEVMVNEGLHDAYICHKEAFCHDAILIPGGFGYRGVEGKIAATRFALENHIPFLGICLGFQVAVIEIARDIIGLQNANCTEFDPATKYPVQKGI----KDLGGTMRLGCKKVLIKDGTLAKRIY-GTDTIYERHRHRYEVNPN-YICIIEKAG-----FVFC----GTD-EDGIRMEILEK--KG--DECFIATQYHCEFKCRPLNPCRVHRKFEECVEIAINLKDIDMTN-PKNRINEEILLPNGRG-KDVKVVIFGCEELKAKAKGV-ADYIFGPEDICKFAEDKKAFKKIVNDAYFFIAEATLMANIGKCL-GQVLGPRGKMPVKARCRNCLTLHVPVGTRCMDTQKICENIMAILNRITGKLERGHC--NIKNVYVKTTMGMGDPKFH-HKKYCT--PRHPWEKDRIDEENKILVKYGLK---NKREIWRCEAMLCCI-RC--QARYLLCRYKIL---SDKATLDDVLCLTVENILDRRLQTIVFKKNLALCEKQARQLITHGHITVNGRRVTVPGMLVEAQYEDTIILCPVCTEKTALLAEKENKLTLIVDRKATKEDIKREVECRFCVKVEGINIKKAIVKLAKEY--SAEEIAERIGIYCINGEKRGEIDL-PEIFNYCVREDLIRKAFRAICLCLRQPYGCCPLAGLRRVG------HTTKP--GLGICRMP-R--IAGGC-----R-VVGIACAVGGKCAHCPRCTKKLYVGINEKERKMAKFCAIAMTACADAVRKRGHRFCECLPL--PVVVEDAVCG-IKKTKDAVNLLKCIGLYEDILRCKEGK-HIRAGRGKMRNRRYKVPKCLLIVCLPGVDVACMDCLCIRKLAPGGVGGRLTVYTECAARLECHGYKFEILVDPDAIERIR--KGN---IDIENDLAMPEVYKDARKGEKACEECLKEAFKTTDIAQIVVDIVKKGQIQLTTEQRREMYDERRKQIVNIIAREGINPQ-TNTPHTPYRICQAMEEAKVKIDPFKCAEEQVQGVLKAIMPIIPIRFEKAKLAVKLVGDAYGKLYGELAKCG--YITKEEWGKDGCWMGIL-EVPAGIQGDIIECLCRRGGDICKIKDGTVIDHIPCGKA--------LRVLCILGIRD-DVDYT--VCVGMHVPCCKME-Y-KDVIKIENRCLDKNELDMICLTAPNATICIIKNYEICEKFKVELPPKLIGI--IKCKNQNCITN-TR-EPVKPEFEIV-SRH-PLVLRCVYCENEALVNEIRCLVEICRQNCAKIWRDMAERLANGRRRYA--SINLYKIDKFAKDG-----DVIVVPGCVLGVGKITKK-VTIGAVHFCRAATEKLVRCGCAF--MCLCDVAK--ANPKGTNVKIPVRCFCCGRVIACDYGRYLRRINEIRCEGR-EPTAEEIEKIFDDLGVERYCCRRMIICHLKVGRYILI------DDVPCKIVEITMCKPGKHGEAKGRIVAIGVFDNQKRCVVYPVKHKVKIPIIEKKNAQVQLMDCETFETGMEVPYWEA-MGVRKIKYMIKAKIYTDGVVDV-----VGAFGQTEGLLGDDL----DLRDLQKCGKIGRIA---AALETIDR--------IGPCKAKVEIANVEDVRVQKRQKIIERAINDCDCIIVVEGRND------VLNLLK--YGIKNTIAGTN--IPETVKKLCKERTV--TVFLDGD--------RGGDL------ILKEMLQV-AEVD---FVARAPPGT-EVEELTYKQ----IVKALDVAYNA--GIKNIYGLKLG-HI-TKKPMQEIIIDKVVVNIGVGQA---GDRLTKAAKVLEMLT-GHKPTQTLAKKCVRDFNIRKRLPIGVKVTLRKDDAVNFL-NKALY--VK---DYK-IPDYCFDKHGNAYFGICDYTDFKGMKYDPDIGIFGRIVITRPPEITAVRP-IVKLGIDYYILVAGCPGAGKCTFVQALAEFFNAR-GK-IVKTMERPRDLDVCK---DITQYTELEG------SMEMTGDIL--------LLVRPDYTIFDEMRVTDDFKVYADLRLAGV-GMVGVVHATRAIDALQRFIGRIELGLIPQI---IDTIIYICNGQVAQVLCTEYTVKIPYGMTQ--EDLAR-------PV-IVVCDL--ITGKDLY-EGKCGKKPTGG-NLKQAKK-KRRFELGREPTLTKLG--TKV-ERKVIRTMGGNCKAILFTADTANVYDIHEKKIKKVKIITVKENPANCHYVQRNIINKGTIICTEIGEAIVTCRPGQDGVINAKLAGRIGREALELARTLIEPGTKLLDVAEAMEKFVI-EQGAKPA------FP--VNLCINNDAAHYTPACGDKKVFKTGDVVKVDFGAHIDGYMCDTAITLIDATREALDAAICLVRPMRCVNEIGGRIADVIGCFGFKPVRNLGGHGVERYDLHATLF-IPNDHAIAIEPFAC--TGIGMIHCGPPGNILREHNNTLICQAEHTILVLNDEIIVTTCH-PKKCH-HECQYYCPICETLCIG--CGICIRRCPFGAIRIVTLPDELNKN-VFHRYGVNGFRIYCLPT-VVPGKVCAILGQNGLGKTTTLNILCGITVPNKNQ-----YVDY---IPKVV--SGT-IGEILRKNNEN---G-NFDEVVCLLNLENALCKDVKECCGGELQKLAIGTTLEKEADIYLFDEMTCYLDIGERLNVCNIVQDLCK-----KKTVIVVEHDLAILDWLADCVNIVYGDP--GVYGIFCEPLCTNRAINAYLCG----FLREENVRIRFCLDVHAGQ-IHTGEICGVLGRNALGKCTFVMMLAG--VMNPDE------GY-------KPQYI-STD---FKGTVCDLILCGGEMQRLCIAITLCREADVYLIDEPCAHLDCCYRMVVAKVIRRVMENTKKTALVVDH--------D
Thermoproteus_neutrophilus_V24Sta                       GAR-VVVIPCNPLCT-----QDAWRGMCERDYYNAIGFALC-----FQPTVTLDDGADLTCTIHGGTEETTTGVLRLRALKCAGKLLYPIIAVNECYTKYLFDNRYGTGQCTWDGVLRATNLLIAGKNVVVAGYGW-VGRGIAMRARGLGARRVIVVEPVRALEAVFDGFEVM-PMDEADIFITATGNIRAINLGHIFKMKDGAVLANAGHFNVEIDVAGLERV-AVAKRQIRQY-LEE--------YTLPN-GRRVYLIGEGRLVNLVA--AEGHPCEVMDLCFANQVYKLPDELDREVARLKLKTMGIEIEELTEEQRQYLTCWDIGDLEDAKQKIRELVE-LPLRHPELFKHLGIEPPKGILLIGPPGTGKTLLAKAVANEA-----NAYFVAINGPEIMCKYYGECEARLREIFEEAKKNAP------AIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDGLQERG------QVVVIGATNRPDAVDPALRRPGRFDREIHIPMPDKRARREILGADLAALAKEAAMAALRGPPGVGKTLFAKA---VATECGANFIAVRGP--ELLCKWVDEIDCIAPARGCRLGDCGVTDRMVNQLLAEMDG--IGTLKNVVVMAATNRPDILDPALLRPGRFDRGIAWIYCCCNNTIITITDLTGAETVARVCGGMVVRADKDKPCPWAAMQAAYKAAQLALARGINAVHIKVRGPGGY-GMKVPGPGACAAIRALARCGLVIGRIEDVTPIPHDIIRPPCGRKGRRGPAGRYGARYGMGIRRKITAIEVKQRGKHRCPCCRCLVRLQRIAFGIWKCPKCGFTFAGGAWTPVDPGAVARIVNGADVMRPGIQQFIGDFNKGDVVGKVLLNVHHLGDYGYMAMWYRKIGR-EVHERLMRKILIEWRRAPCIVRVERPFRLEKARKLGYKAKQGVVVVRVRLMRGPFNRRRPDCGRRPKRMGVYGITT-WKCWRQVAEERAARRYPNLEVLNCYWVADDGVYRYYEVILVDCNQPTVRADPLYCGICGREVPCR---------RITRRLVVDIIHVPGLNAPVAKIRLE---NGLEFLNYAAEGLYVGQEIGEAACPKTGNVVVLGKAPEGTMVFNVEKRPGDGGKFARCGGTYALPCGRTMEVDARGRATVGLVAGGGRIEKPMVKAGKKYYRARAKAWKYPLVRGKAMCPYAHPHGGGCHQK-GG--TP--VCK-TAPPGQKVGFIGCRRNAGTLAHVDHGKTTTCDCLLMGAGLLCP--KVAGKALAMDYVPIEQLRQMTVKAANICLYFEYGGKP----YLINFVDTPGHVDFTGHVTRCLRVMDGGLVVVDAVEGVMTQTETVVRQALEEYVRPVLFINKIDRLIKELRLCPQEIQQRILTIVKDFNALILTMIIEHVPPPNVAQKYRIPRLWRGDLNCEIGKALLEADPNGPTVIAVCKVNKDPHAG-LIATGRVFCGTIREGDEIYIIGR-KMKKKVLQTYIYMGPCRIIVPYMPAGNIVALMGVDEARAGDTEKMRYICEPVVTVAIEPKNPAELARLVEALKDLVIEDPTLDLKIDQETGQILLCGVGTLHLEIATW-LLKERTKTEFTVCPPLIRFRETVRERC-QVWEGK------SPNKHNRLYFYVEPGIQYLREIRDYIVQGFRWATEAGPLAQEPMRGLKVVLTDAVVHEDPAHRGPAQIMPATKNAIFAAVLCARPTILEPLMKLDIKVAPDYIGAVTCVLNKHRGKILDMTQQEYM-AYLRAELPVLECFT-ICDELRAAAAGKIFWCMQFCRWAPMPDLLCNALIQIKNAEAMGKRQVAIWPVNKLIYYTLRVLQRHGYVGEVEYID-DGK-YVVQLLGK---INDIG-------PIKPRYPVKYREIVQ---WEQ-KFLP--ARQIGILVICTNQGVMCHVEAKEKKIGGVLLAYVYGDLQVAVVGPPCCGKTALLTCLTPCIV---LDQQCDLNTIALA-TVRNADLN-------EYGIYHALLEDILKATGRIRVFTKPVHCKTYVEKPFKY-----AVVGRDYALCD----NDMTCVKDVPADLLIAELARYIRENVPQVKPPVWAPFVKTGANKERPPMTQ-D-WWYVRAACLMRKLYLYG-PVGVGCLRTAYGYRAK--IGDKTRPERTRKAGGAIIRKLLQQLEQAGFVAKTKG---GRVLTPEGKCLVDRLANAEGHIAGRLATYIAGLR-IVVVNAEKLVVTGDEKMVVEWFKRKICEWGTHYNPEKAGPKIPRRPDRVFKRMVRGMLPK-RAECGGKVAPNPQFQDCLKQMGLDPNAVLQRVQEEVKKYG--KYPIQKVEVEV--VPPAKYDVKVHLPPIGDLFLKLFGKDT------GAHDARN-EVIGDLTFEQLVEIAVLKRDELKCRCLKAAVKQLLCTCKAMGITVGGKPAGEVLKEVDAGKAGMLHAVVVEDRPTCPLYGKEVVRPVTVLDAPPLFIWGFRL-YTLDPTNGYRRCIAEGKTVCPKEVFTAGQLVDVIAVTKGKGYQGVIKRFGVTILP-RWHKHRKGHRR-TGTIGP-QAPA-LMFTQPRPGQMGFHQRTEYNGFLHYGVIRGPYILIQGTVPGAKKRLVVLRHPARGGGIHPREAAEHHAYAAGPGLGPALRVGAVLARALAIRLGVPVVPVHHGVAHIEVARYAT-----GACDP-LVVLICGGHTVVAGYCD-GRYRV-FGETLDVAIGNAIDMFAREVGLGFP----GVPAVEKCAE------SA--ETVVPFPMPIVG-----QDLCYAGLATETAYYMLAEVVERAGGVARCRRLKEILRAV-GEEHGAVVKVVPDEYAGDNGAMIALTGYYAYRRGRIRLYGTNPTDVDQVAREIVDLAKKMGVQVRGPIPLPTRRLMVTVRRAPCGQGYHTFDHWEMRICKRLIDI-EACERVLRRLMTIRV---PDTVKIELIKFGILCPEMIRKYCVMEVTTCEVYDEGGL-PVRGGIADRRL-GVAEPGARCETCGQTHDVC---PGHFGHVELVKPVIHVEYAR----IIYDVLRTTCPNCPH-------CRDRLAKVPN--EDR----PEWAILKVLPVPPPHVRPCIQLETGIRCEDDLTHKLVDIIRMNEKLKIAIETGAPTNVVDNLWDLLQYHVATYFDNELPGI------PVAKHR-GGRPLKGIAQRLKGKEGRFRGCLCGKRVNFCARTVICPDPHICINEVGVPYDIAKILTVPERVTEWNVDVLREYVMRGPETWP-------GANYVERHLVDGDIVLFNRQPCLHRVCIMGHIVKVLPGRTFRLHLAVCPYNADFDGDEMNLHVPQTEEARAEARTLMLV-EKHIITPRYGGAII--GARQDYIIGAYLLCGKQVICHFLPDGFRCGRLEAMPGFTVEETFENKITEGYLMAKTGARGCIVNIVQMVATLGQQTIR--------GERIRRGRTLPHFPPGDI-GPHAGGFVGRCFRCGLTPVEYFFHAAAGRDGLIDTAVRTAQCGYMQRRLINALQDCAE--VALVYRVLPECVEVDIEKLE-EIGFGIKALRFFIRMPECDEYCCDEVEELLRCVEGVVKGPLGEIAKEFRNT-PVAMEVRDGK----VTYKGVLRNMFLGVTKGWRYKLKVIYTHFPMLVKVQGCQ--LVIENFLGRKCKIVVAI--PKGVKVEV---KGKED-IVIEGIDRDVVCQLAAAIGVDEAGRGPVVGPMVIAVVDCKRLCPERRERLYQLIEC-VPQVAAACIVAKVVRDRLVALLKK---EVGGRIRRPLLVVE---GGGVIEYLDADEGAVGCIIPYLEHNQCPRNQYEAAMAKQGLPQCN-FLYKLDCRGHMLYY-PERPVTTRGLELVG--YCRRPA--------GQNAVVAYTGYNIEDAVILNKACVERGMFRCVFYRTYETEEQKYPGGD-KIEIP--DCCVK--GYRGPEAYCHLDE-DGIAPPEVYVRFY--TTLEAE--RI--LKERRDACRRGEKGIVDRVLVKVRLRELRGDKFACRHGQKGVVGMLLRHEDMPFTENPHALPCRMAQLLECMAG-------KGKEVMYCGITGERLVADIFIGVVYYQKLHHMVADKIHARARGPVQILTRQPTEGRCREGGLRLGEMERDVLIAHGACALLYERLVECCDKYTMYVCEL--CGYAYKLLLQELIALGIYPKLDTGLYVDALGGFPGPYGETRGRICEEPRGCG-GFGFDPVF-IP-------EGFD-KTYAELGDEVKKTAVARAVIKPGVGRVRINELWPI-EMARLKMCEPDIDVNVAGGGYMGQATAVRIAIARLKEVYEKYDPYMLKGDPRRAEPKK--PGIKHARCKRQKAYRTRNLTPGKRVYGEREWNPYRCKLLYLGAACGTTPCHMCDIVGERGLIYCVEFCPRVAQPAQAKILADNGYVM--LVIKA-----MCIDVTAPATETFKQ-EINTLVFYNPAMEKN--RTDICRDAAELIKKNDIDPFGCPAPYIHAAFRA-LRDEGLLCATATDTAVLVGRYPRKCLRRYWCTVR-KTPFYIELGLRNLVGFIARVAACEDFCIR--PLMCYWEGHYFRTCVAVARGARDADDALQ-NVGLAGPPGIGKTTVVHALALRRICTAE-------GAKCEEEALRCIAKCCLGDLRAAINDLDPGLRRYICLKPVVLPHTEGRYQNYRFGKARIPIVERLINLMMGKKHKAYNIVKRAFDIVYYKTGQNPIQVFIDAIVNTAPREEITRIIMGGIAYCVCVDVCPQRRLDLALRWITEGARACC-FNNPKPIEECLADELVAAAAND-PK-SYAVRKREELERIAAACRRG-SRTHGWGRVGQHRKCGGCGGKGMVGF---HKHKWC-LVMKYGECGTGWPFYG--KHGFKLLGGGDVDLPIVVYTPAACRCAVEKIEKAGGGKTLEELL------NLPMDEFIKLLPARQRRCLKR----GIKTHCRDMIILPEMVGLTIHVYNGITYIPVFICPWHIGHYLGEFALTTKVVQHGEPGLKATRCCLHIAAKADNCGAKLVRVIGVVGHYCKTVHRRIPGAGVGDMVVVVVREGKPE---LRKQVFRAIVVRQRKPFRRPDGTWVAFEDNAVVIVTPE-GD-PKGCEIHGPVAMEATLR-WPTIANLARLAADILGVGVCRVKI--SPEAVEKLDEVVTKDDVRALIDQGLIWAEQERGVCRGRWRVRHVKKR-EGRRRGHGCRKGRRTDEE----EVWKNKVRAMRRFLNTLKRCGR-LEPRVWRQLYEMVKGNYFRDLGHLWEPRTELGRLVKEGKIRTIDEVFANNYIIKEPEIVDVLV-PGLGERNQFQAVVVVGNEDGYVGVGIGKARQVRQAIEKATREAKLNLTPVRRGCGCWKCCCDEPHCVPIVVRGKCGCVEVTLIPAPKGVGLVAGDVAKAVLRLAGVRDVWTKTRG-----DTRCTLNFAMAVYNALEFLEYRLCKYGYIDCEILKT-PLGTRIVIYAERPCRIIGKKGAIVKEICNILMNKLG-VENPQIDVIDVCKIEAPEMFPKVVAYRIANAMAKGVR-FRRVMFVAVRQLMEA-GAKGFEIVVCGKLCT-ERARFEKHTYGKLYKIGYDAKNRVRRAVVHVLLKPGIYGIEVRIAPA--ALQYCDLKKILTPAALARLDNIRVVRPELAEALEQQLIALACCGRVRVPIDEDTLKEILHAGTLDPKVCGVLPIAVAEGTKVLLALCRCDKVYFQGIIYQRPPLRCAVRQLRTRQVYCIEL--LGTYARKLIHDIGEVLGVGANMRELRRVAVCCYTEEET--VTLPIEEIARHLPKIWVRDCAVDALCNGAPLAAPGVAYFTLKGELIPTVCRPPGRVPLCRRL-FWTAVVATVYILMTITPLYGG--TLAHLGIGPIVIAGILLEVFAFC--GLLNLDLNK-REDRLKFTLLLKQLLV-ATVIIILLDDLMCKG-----IGCAICLIIFLGVTVLLGYIILYLEMMKVNIPPLRFVYVCVLPIIFAWV--WVQLAGLCA-EDQARQFTQCQLHVPGFRQCEKILAKLLERPINALTVICGFVAGAFAALGNIL---GVWG-------GGTGLILLVEIALQYYALVMREQIMEMYPLVELGVVKFGL---FKLCCGLECYVDLRLVLGDPP--V--SYVRPEAKGLGRQ--IEG-AEV--RGRRVVVVDDVLTTGKCVVGAVNALKNAGGLFAGGKLKRKRQKFRWNDVTYKRKML-GLVEKYDPLEGA------PMARGIVLEKVGVEARKPNAAVRKVRVQLVKNGKVVTAFVPLDGCLNYINEHDEVVIERIGGPEG-RCLGDIPGVRFKVVK--VNGVCLWAIWRGK----KQKPTRLVPLEKYL-----SAGVRLGTRLC--NRYLEERGFIFAVRP-DGLRIFDIKKIDERLKIAAKFIARY--PPDRVLVHTTRPYGFKPVQMFCKFVGCRALTGRFIPGTLTNPNLPHYQE--------VDLLFVVDPKLDAQAVTEAAKMGIPVVALVDTDTPHQYIDLMVPCNNKGRKCLALIFWILAR-QI---LRERKMCIVIRRDLRICCGKAAAQAGHAWLAEGQKKIVLAAENLEHLYELYKKAACLDLPAAVVVDAGLTEIPPGTPTALCVGPAPDELVDAVTGCLKLKLIVITGGVMCGVGKGVVVACIGRILRARGVCVNAVKIDPYINVDAGTMNPYAHGEVFVTYD--------G-----GETDLDLGHYERFLDVELCKRNNITCGQIYLCVIEKERRGEYLGQTVQLIPHVTDEIKRRIDVTLVEIGGTVGDYEQLPFLEAARQLRLELG-HDVLFIHVALVPLLKTTGEFKTKPLQHCVAELRRYGIQPDAVVVRCEKPIDAGCVKKIALFTNVPQCAIFNCYDVDTIYRVPLLLEEQGLPDAYLCIIEALKHDAMVVLPGFGKRGTEGMIECVRYARVEKIPFLGICFGMQLAVVEFARNVLGLKGANCTELDPDTPHPVQREV----DVLGGCMILGDREVDIVQGTLAACLY-GAPHTVERHRHRYEVNLC-YLPKLADAG-----LRVC----GWR-RDVKRVEIIEL--PG--HPYFIATQFHPEFKCRPTKPRPVFRRFRQCVELILVLREVDLCK-PENRINLLVELPHPP--KPNKVAAFAHGAFEVQAKNAGVDAVICRDQVEGLCGNKRAIRKLAKQYDFFIAPPDLMPLLGRVV-GPIFGPRGKMPVRVKLRNEPVIKVRIGAEGQKPEEVLENALAVLEDVNRKFCLRQ---YLKDVYIKKTMGMGGLKKP-KKKYLAGKPKKIWNKQLLLEELQLMGEYGLR---NKKELWLARAHLKWI-VR--RARCLLYKMGFI--EDPNVPLDRVLCLDVRAILERRLQTIVYRMGLAKCIYHARQLIVHGHIAVAGRRVCCPGFLVPRELEDKIIKRFVVTEKALRLAERENKLTVVVDRCATKKQIADEIQRLYNVKVEKVNTKKAYVKLEREY--NAIDLLCKLGVYGPDGAYIADIDP-PLHFMEPVRPDLIRRAYLCALCARFQPKGVYEGAGREHCC------ECFGV--GLGIARIP-R--YKGCLWP---R-GCFAPNTRGGRRAHPPKVEKKLHEEINRKEKNLAIRCAIAATAYRCWVAARGHVVDKIPAL--PLVVVGDAEK-VGRAKEARKLLEALGLWPDVERAAAGV-KIRCGKGKRRGRRYKEPKCVLVVNFPGVDVVPVDGLNMLVLAPGGAPGRLTLWTVPAAKLDRGGDHFEILIDPDAALELK--LGK-P-LGIDKVLIHEEIYKDAKKGLRACEQCLKKAFGTTDVRKIAEIIIKEGEIPLTCEQRRKLVEDKKRQIVEWICRNCIDVR-TKTPVPPQRVENAIEQARVCIDPFKCVEEQVQEVLKEIQRIIPIKVATARVCLCVCCCHAQRVKGLVAKMA--KIVCERYRPDGCWEAVL-EMPAGIQDMLICRVNDITHGVCKIERGTVIDHIPAGRA--------LAVLRVLGITG-REGVR--VALVMNVECKKLG-R-KDIVKIEGRELTPEEVNIICAVAPTATINIVRDYTVVRKFKVCPPEVVKGR--FRCKNPTCITNAPR-EPVEPTFLLV-RRE-PPLFVCTYCTNRQLRMLARFLRKAAAANCARIWRVVAELIERPRRCRV--VVNVGKLNRVAEDG-----DVVVVPGKLLGGGELRKK-VTVAAVKVCPKAAQKVVEAGGEL--LTIPELVR--RVPKGTRVKVPVRCFTCGRPLGHLYPIFKRRV--LAGE---RP-----GEVLDCLGVYRYCCRRTLLCHLKEGCYVVI------DGEPCRVVEIEKCKTGKHGCAKARIVAVGVFDGGKRTLCLPVDAQVEVPIIEKFTAQVQLMDMRDYKTGAEVEVWQI-LDRFKIKYMIVAQIEVNGCVDI-----IGAFCQTEGLLGKDM----DLRELQMMGRIGRIA---ALIECIER--------VGPYLANIKVLEIKDLREEKRRRIIEKAVEKCDCVIIVEGRAD------VVNLVK--HGYRNVIAGICRGIPQTVIDLCKKKCV--TVFIDGD--------KGGEL------VLRELLKV-AHID---YIARAPPGK-EVEQLTAKE----IAKALDLAAKK--GVKVIVTARVG-PL-TKVPMQRIYIEKVVVNIGVGTG---GEKLEKAADLLKELT-GAEPCKRRAKRCIKDFGIRKGEPIGVAVTLRRDKAVEFL-TKALQ--AV---NNR-VKRTCFDERGNVCFGIKEHILLPGVKYDPAVGIWGRIIIVFPPEITAAKP-VVRKCIWDYILIAGAPGAGKTTFAQALAEFYLCK-GK-IVKTLECPRDMVLCP---AITQICKNLA------TCEEVHDIL--------LLCRPDYTIFDEMRDTADFQLYVDLRLAGV-GMVGVVHATCPIDAVQRFIRRVELGMIPCI---IDTVIFMKDGEVKKIYALCMVVKVPAGMRE--EDLAR-------PV-ILVKDF--LTDEVEY-EGGDLKKPCGG-KKRRVRRTKKKALGGGPPQIPKLG--END-VRVVERVRGGNIKVRMREARFANVYVPKEKRYVKARIVCIVCTPANPDYARRNFIVKGAVIQTEVGKAVVTCRPGQDGVINAVLVGDVVHRALKYAIDLAQAETPVLEICEKVEGFIR-ANDAKPA------FP--VNVCINEVAAHYTARRGDVLRLPKTGVVKIDVGAQRDGYIVDAAVTLAKAARAALETALGAVKPGVKAWQVGECVERVIKCFGFNPIYNLTGHKIERYILHAGYV-VPNGDVYAVEPFAT--NGEGYVTDGRDITILVERCRGYVAQFEDTVYVCEDGAVPLACQ-PKKCG-QECVKYCPICEALCIG--CGICVHKCPFQAITVVNLPDELEKD-CVHRYGPCGFKLYRLPL-LKRGKVIGVLGRNALGKTTMAKILAGELVPNKIQ-----YIEL---IPMYL--KGP-VADVVKKA------G-IREDVLKRFGLDRLLDRRVEDLCGGELQKLAIAAALCKDAEVYIFDEPATHLDIVERVKIADAIRDLTA-----DKYVLVVEHDLTVLDFLADNIVIVYGKP--GAYGIVCYPAGAREAINEYLCG----YIPCENMRIRFRLEVACCY-ICKGEVVGVVGPNGIGKTTFLKVLVG--EVKPAK------GY-------KPQYIRDIAVRNQDVPVCLWLLCGGELQRVVVAAALLKKADLYVLDEPMAYLDVEQRITVARTIRRIIEECEAAMLVVEH--------D
Thermotoga_maritima                                     GAK-VVITGCNPLCT-----QDARRTHDECIYRENLMKVLD-----ERPDFIIDDGGDLTVICHGVCEETTTGVRRLKALEETGKLRVPVIAVNDCKMKYLFDNRYGTGQCTWDAIMRNTNLLVAGKNVVVAGYGW-CGRGIALRAAGLGAR-VIVTEPVKAVEAIMDGFTVM-PMKEADFVITACGNTDVLCKEDILCLKDGAVLANAGHFNVEIPVRVLEEI-AVEKFEARPN-VTG--------YTLEN-GKTVFLLAEGRLVNLAA--GDGHPVEIMDLCFALQVYMLPDEIDERVARMKLDCLGVKIDELTEKQRRYLRCWEFIGQENVKKKLCLALEAAKMRG---------EVLDHVLLAGPPGLGKTTLAHIIACEL-----QTNIHVTCGPVLVKQ--GDMAAILTC-LERGD-----------VLFIDEIHRLNKAVEELLYCAIEDFQIDIM-IGKGPCAKCIRIDIQPFTLVGATTRCGLLCCPLR--SRF------------GIILELDVEIEDAAAEMIAKRCRGTPRIAIRLTKRV---------RDMLT------------VDD-------EGLDEFDRKILKTIIEIYRGGPVG--LNALAACLGVEADTLCEVYEPYLLQAGFLARGVVHIKCTFNNTIITLTDKDG-NTLTWACGGTVGFEGTRKGTPYAAQLAADKVAREALRMGIKKVDVLVKG---------PGPGREPAIRTLQGAGLEINQIKDVTPIPFNGCRPK---KRRR????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????VLAIEYDPNRCARIALLLYA---DGEKRYILAPKGVNVGDTLGPDAEIRPGNALPLEKIPVGTLVHNVEFTPGKGGQIARAAGTYCMPCGELRKVHIKCYATVGVVGNEDHKNEVHGKAGRV--RWLGRR---PHVRGVAMNPVDHPHGGGEGRG-KGH-HP------TCPWGLPTKGYKTRRNIGIMAHIDAGKTTTTERILYYTGRKHFIGDVDEGNTTTDWMPQEKERGITIQCAATTCFW----KG----YRINIIDTPGHVDFTAEVERALRVLDGAIAVFDATAGVEPQCETVWRQADKYNVPRIAFMNKMDKVGADFYMAVETLVTKLRANPIPVQMPILDAVIDYLPCPLDLPPVKGWRVCDGEV------VYRKPDENEPFTALVFKVQVDPYIG-KLVYFRVYCGRLEKGCYVYNCTK-GQRERICRIVFMHADKREEVDYVRPGDIAAGVGLKVCQTGDTEKIDF-PEPVICLAVEPVTKADEEKLVKALLALCEEDPTLQVRVDKETGETIICGMGELHLEIVVD-RLKREFGVNVRVGQPQVAYRETIKKCA--EAEGKYIRQTGGRGQYGHVILRIEPGGVIPKEFMPAIEAGIKEAMMAGPLAGYPVVRVRAIVLDGCYHEV--DCCEMAFKIAACMAFKEAMKKAQPVLLEPIMKLEITTPEEYMGNIICDLNCRRAKVECLETRGHL-KVIVAKVPLCETFG-YATVLRCLCQGRACYIMQFCHYQEVPDPIADMLTRIRNANMVFKEYTDI-PACNLKKKICEILKREGFIADYKYIE-DGI-LRVYLKYKGGRKNRER-------VIHGIVRVCHAGRRI---YVDKDHIPKVKNGLGIAILTTCKGVLTDKEARQLGVGGEVIAYVW??????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DACGKVLGRLATRIAGDY-VIVVNADKVVLTGKKLDQKVYYW-HCGYPGGLKC-LTARQMLEKHPERLIWLAVKRMLP--KNRKGGKATPAPPVGPALGQHGVNIMEFCKRFNAETADKA--GMILP-VVITV--YEDKCFTFIIKTPPACFLLKKAAGIEK------GCCEPKR-KIVGKVTRKQIEEIAKTKMPDLNANCLEAAMKIIEGTAKCMGIEVVD-------------KIGMTRVFVGND-----------SVPVTVIKAGPCVVVQKKT-VEKDGYNAVQLGFEKGQVIKV-DVFEKGEYVDVTGWTKGRGFAGAMKRWGFCGGP-KCHGCK-FHRE-LGCVGQHTEPAKIWKGKKMPGRYGNERVTVRN------DPENDLLVVKGGVPGARGGLVLIRCAKAG-GVVPEVAARHHAATYGPGLIGALLVGLCAAKGLAICLEKPFVGVNHVEAHVQAVFLANP----DLKPPLVVLMVCGGHTQLMKVDEDYCMEV-LGETLDDCAGEAFDKVARLLGLGYP----GGPVIDRVAK------KGDPEKY-SFPRPMLD--DDCYNFCFAGLKTKAVVDILVEKTFRLGGVAANCMLREEVRKR-AERWNYEVFFPPLELCTDNALMVAKAGYEKAKRGRIKLKAYDHELLDECAKKIVEVAKCTNCKVCGPIPLPTERTLYCVLRCPMK-HKDCREHFEKRVHKRLIDIIDPCPKTIDALMRINL---PAGVDVEIIQIKIACPEVIRCWCGGEVKKPETINYRTFKPERDGLFCERIFGPVKDGTVCERCGVRVECREARRKRMGHIELAAPAVHIWYLECIPCVLGTLLNMCTCDLPVFEGALVYVEAELKKLPC--SCK----PEWMVLEVVPVIPPDLRPMIQIEGGRFATTDLNELYRRLINRNNRLKKLLELGAPEIILRNEKRMLQEAVDALIHNGCDCEGKRCRRAVLKDR-NGRPLKCLTDLLKGKKGRFRRNLLGKRVDYCGRAVIVVGPNLKIHQCGIPKKMAMELFKPFV--------LAKLLGEGCCCKT-----------VLEEVIKGCVVLLNRAPTLHRMCIQAFEPKLVEGNAIQLHPVVCPFNADFDGDQMAVHVPLCAAAQAEARFLMLC-RYNIICPAHGKPIC--LPTQDIIIGCYYLTGRVIFNGILPDGYEKGFLT-------EEQRKCEINPIYMMVNCGARGNIDQVKQLAGIRGLMIKAYDPRCREIKCKIFKGQAIHEALTFDY-------PVDKNLREGVDILQFFICTYGARKGQVDTAMNTCFAGYLTRRLVDVAQC??????????????????????????????????????????????????????????????VKGPKGELCQEFLP--YVKIEVEGNE----VTYWCLIRNMVVGVTEGYKKELEIVGIGY--RAQLQGNT--LVMNL--GYAHPVVYEI--PCDVKIEV---PAPNR-IIVCGIDKQRVGQVAAEIGVDEAGRGCLAGPVVAAAVDCKQLCPAKRERLLDEIDQKCKLIGAACIVAKVFRDRLMCEFHRMYPQFCGNIIPERVVAR---MGCLIPFLEHDDAKNCGYVILAEHDGIVKEVDAARVVVHGNPVVDEYRLLKFVRCNQDTMINQKPVNEGDFVKKGDPIADGPATDMGELALGRNILVAWEGYNYEDAILVCQELLEEDVFTCIHIEVYETQARETRLGEITADIP----------NVCKELLKNLDE-NGIIRVGAYVKII----RCVFG-ER--GRDVKDTCPHGVEGRVIRVLVRVYVACRKGDKLAGRHGNKGVVCNILPKEDMPFLPNPLGIPCRMGQILETHLG-------WGKVVLRDGRTGEPFDNPVVVGYMYMLKLIHIAKEKIHARCTGPYCLIHQQPLGGKCHFGGQRLGEMEVWALEAYGAAHTLAEMLTIKCDDI---------KGECFRVLIKELRGLALDVRLDCGLVIYCLGGFPGVMDRVEGRIANEIRGTG-GFGYDPFF-IP-------DGYD-KTFGEI-PHLKKTAVARVYLRPGEGKVKVNNDYFKNPAWTKHAIEPDLVIRVNGGGLCGQCGAVRLGIARLRPVLKKYK--MLTRDPREVERKK--YGLKKARRAPQFCKRTKCY-PLCYVYEDCT--SCQPCLLEIGGGTGYNAAVMCRVVGEKGLVVCVEYCRKVIVPINLKLCRRQPYLVGNYKLET-----RFITAGGNLGNLLER-NRKLLGFFNFAIEED----D------------D-EKITTPKDWI---------------VELEPFEIVEG---------IFIDPT------EKINRRDAIVIKLCPGVAFGTGLH--PTTRMCV-FFLKKYL--KEGNTVLDVGC--GTGLYGPPGCGKTCVFCLLKLKKATEVL-------NIDLEECVEKAIVRHCEGDARKLLNTLRRAEKRQIPPDPVF----------------GDVLVAKLINRVMGKKTIAQKIVYGAFDIIREKTKKDPLEVFRQAVENVKPVLEVRPRRVGGATYQVPIEVQEPRRTCLALRWIVEAAR----AKKGRPMKEKLAEEIIAAYNNT----GTAIKKKEDTHRMAEANRKRVGRGPGCG-HGKTCGRGHKGQKARGCG---KVHIW--FEGGQTPL-----QRRLPKRGFKILGDGELTKPLVVKAHAFCKCAVEKIECAGG------------------------------RCRKK----GIKTWCRACMIIPEMVGHTIAVYNGMKHIPVYITENMIGHRLGEFAPTRRFGGH------ADKKAKKGELKADNCGAKKLRVIRVIG----GFHKKY--GTVGDIVVCCVREAIPNCDVKKGDVVRAVIVRTKKEIRRNDGTYIRFDDNAAVLIDKF-NA-PRGTRIFGPVARELREKGFMKIVCLA???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????----------------------------VETQGVMKEIQYEEFGKNLCFRVVAIVGNKNGKVGLGIGKAREVPEAIRKAICAAKRNIVEVPVING----------TIPHEVIGRQDACKVLLKPAAPGTGIIAGGTVRAVVELAGIQNILTKCLG------STNPLNLALATMNGLKIIKNKYYHAGICEIYVERPDAERINITVKTARPGIIIGRKGCEITCLREELERKFN--RRVVINIEEI---KTPELDAQLVAECIACRIEKRAC-YKVAMKRAIMNAMRK-GAQGIKVMVAGRLGGAEIARREWYLRGRLPL--QKIKAIIDYGTATAWTKYGTIGIKVWIYKG--DADI--?????????????????????????????????????????????????????HGGTLDPFACGVLIIGVNQGTRILEFYKDLKKVYFVGEYDQVPPAYCAKLPPKRVKIFKIWD--VGTYIRCLCMDIGYKLGCGATAVELVRECVGPHTIEEC--LNVPLEKCLEWLPRVVVHQECTKMILNGCQIHLEMVRVFNEEGRLL?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????LEKTGALMEGH---FILCCGKHCYVQCARLFEFPR--S--LFAEREN-GVMKL--RRG-FFV-KPGEKVAVVEDVVTTGGCVKEVIELLKEYG-MPTINQLIRYGRKPK------------KKKCKAPALQGN------PQKRGVCIKVCTMTPKKPNCALRKARVRL-SNGIEVTAYIPGIG--HNLQEHCVVLVRG-------GRVKDLPGVRYKIIRGALDAAGVEGRRQCRCKYGAKRPKDVVTMKQLL-----EAGVHFGHRTRRWNPKMAP--YIYTER--KGIYIIDLQKTQQLLEEAYYFVREKACEGATILFVGTKKQAQGVIKAEAERCGAFYVNNRWLGGLLTNEKLRKNLGGLKEMRRLPDIIYIVDPRKEKIAVAEANKLGIPIVAIVDTNCDPDPIDYVIPGNDDAIRCIKLITCVIAD-AY---LEGR???????????????????????????????????????????????????????????????????????????????????????????????KYVIVTGGVLCGIGKGIFCACLARLMKEHGVDVNVLKIDPYLNVDAGTMNPNQHGEVFVTED--------G-----YEADLDLGHYERFLGRDMTRQNNMTAGQVYLRVIEKERQGKYLGNTVQIVPHLTEEIKDRIELLVVEIGGTVGDIEGEVFLEAVRELQMEEGKENFLFAHVTYVPYLRTTNEFKTKPTQQCVQLLRRIGITPDMVIVRCEFPLDVPCMNKVALFCGVPRDFVINLPDTKNVYEVPEILRDMGTDDAYKCIIECVFLDALIIPGGFGRRGVEGKIKAIKYARENKKPILGICLGMQLMVIEFARNVFGYKEANCTEFDPNTPYPVQKRI----LKLGGTMRLGAQKVKIFPKTKLYEVYGGVEEVYERHRHRYEANEEAFPELFKKPGEEGYKLVVC--------AKCDFIEAVEL--ED--HPFFVGVQFHPEYKCKVGAPHPIFAKFDETIELHIQT-GIDYRK-PEQHIRGTIVLPHGTG-KEVKVLVFAKGEKAKEALEAGADYVGAEDLVEKIEKEGFL------DFDVAIATPDMMRIIGR-L-GKILGPRGLMPIEVRTDKTGNIHIPVGKRCFDNEKLKENIIAAIKQIMQMKPAGVKGQFIKKVVLACTMG--------MARYTG-----PLCKLCRREGMKLYLK-GERCYTDKCAFDRRPYAPGQH-GQ--RRTKLILERQFERYVEKAMQKAGDTRENLIQILEARLDNVVYRMGFAINRRQARQLVNHGHFLVNGKKVNIPCYLLRPNDVVEVLIRPIITEKALILRE-QRKYVFEVNPLANKNLVKEAVEKLFNVKVEKVNIKKAVVTLKEGY--TIKELEGEH-?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????IKPIENGTVIDHIAKGKTPEEIYCTILKIRKILRLYD--------VDCADGIFRCCDG-SFKGYICLPDRYLCKKEIKKLCAICPNTTVNIIKNCTVVEKYRIKLPPTIYGFEELRCKNENCITNPAHGENACPCFVRN-EKG---QFICEYC??????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????LYLIRH----------------GEIWNEKGLWQ------------------GVTA---NCLKRVD-----------------------AIYCCPLKRCLETAIREYP-----------------VEFKK--WCCDPNFGGLE-----SMRNVQNR-------------------------------VVKAIMKI-V----------------SQEKLNGCENVVIVCHCLDTCHLK--------------EC-----HQVPKLVKIVINMGIGEGCRNYDLIERHANELAKIT-GQKPIVTRARKCICNFKIRKGMPIGLKVTLRGARMYNFL-YKLINIVLPKVRDFRGLDPNCFDGRGNYCFGLCEQLVFPELNPDEVRRIQGRVCTMPCTVMRILKVCDANKRLEELILVTGPTGCGKCTTLVAMINYLKCE-SV-NIVTAEDPVEYTIEGVT-QCQVFPEIGL------TFARYLRAF--------LRQDPDIIMVGEIRDRETAQLAVEACLTGH-LVLCTLHTNTAAGAVCRLI---EMGIDPHL--LGACLIGIIGQRLVRKLCDEC--KMPGEVRD--EQVKCYFEQFFGKV-PDQIYYPCEEGCPAC-K?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????AGKAVAVALREVRKVIVPGKTAWDVETLVLEIFK-KLRVKPA------FKYATCVCVNEEVVHGLPL--KEKVFKEGDIVCVDVGAVYQGLYGDAAVTLVRVTREVLEKAIKMIKPGIRLGDVCHCIQETVECVGFNVIRDYVGHGVGR-ELHEDPQ-IPNGMTLAIEPMVC--EGDWRVVVKEDG--AVTVDGCRCAHFEHTILITENGAEILT--------------VFP------KG----------------------------IVKRF-PGVVAVDNVDFEVYENEIVCLIGENGAGKCTLIKILTGVLKPDNI------FLAY-----EAV--RGQ-KRTLCCRVDENYMYT-RCKELLDLIGAKFCPDALVRNLTTAQRQMVEICKALVKEPRIIFMDEPTCCLTVEETERLFEIIEMLKC-R---GICVVFVCHRLDEVMRICDRIVVM-RDG--KRIGELKKGEFDVDTIIKMMVGREVEFFP-HGIETR-------SFEVRKGEVLGFAGLVGAGRTETMLLVFG--VNQKEC------GIGLIPEDRKLQGL-VLRMTVKDNIVLPCLLCGGNQQKVVLAKWLATNADILIFDEPTRGIDVGAKAEIHRMIRELA-AQGKAVIMICC--------E
Thermus_thermophilus                                    -------------------------GR-------------------WAP--------------------------RLCDLE--------------------------------------------GKRVLLLGYGC-IGKAVAERLRPFGVA-LFPVAPRPGVYTREDLPALL-PRADA-LLPLTPETRGIVDRDFLARMKEGALLVNAGRGGL-VDTEALLE--ALEAGRVRAF-LDV--------TDPEP---------------L----PRDHP-----------VAGLCEGFCRRVARFLAEQVGRYL-----RGEPLLNVVEYIGQERLKQKLRVYLE-AAKAR--------KEPLEHLLLFGPPGLGKTTLAHVIAHEL-----GVNLRVTCGPAIEKP--GDLAAILANCLEEGD-----------ILFIDEIHRLCRQAEEHLYPAMEDFVMDIV-IGQGPAARTIRLELPRFTLIGATTRPGLITAPL--LCRF------------GIVEHLGVRIT---EEAALEIGRGTMRVAKRLFRRV---------RDFAQVAGE--EVITR--DE-------LGLEKRDREILEVLILRFGGGPVG--LATLATALCEDPGTLEEVHEPYLIRQGLLKRGRAYIHACYNNTIVTITDPDG-NPITWCCGGVIGYKGCRKGTPYAAQLAALDAAKKAMAYGMQCVDVIVRG---------TGAGREQAIRALQACGLQVKCIVDDTPVPHNGCRPK---KKFR????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????VAAIEYDPNRCARIALLHYV---DGEKRYIIAPDGLQVGQQVGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTCALPCGELRKVHGECYATVGAVGNADHKNIVLGKAGRC--RWLGRR---PHVRGAAMNPVDHPHGGGEGRAPRG--RPP-----ACPWGWQTKGLKTRRNIGIAAHIDAGKTTTTERILYYTGRIHKIGEVHEGAATMDFMEQERERGITITAAVTTCFW----KD----HRINIIDTPGHVDFTIEVERCMRVLDGAIVVFDCCQGVEPQCETVWRQAEKYHVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPILDAVVDYLPCPLD-----IPPIKGTTPEGEVVE--IHPDPNGPLAALAFKIMADPYVG-RLTFIRVYCGTLTCGCYVYNTTK-GRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTECIEV-PEPVIDVAIEPKTKADQEKLCQALARLAEEDPTFRVCTHPETGQTIICGMGELHLEIIVD-RLKREFKVDANVGKPQVAYRETITKPV--DVEGKFIRQTGGRGQYGHVKIKVEPGGVIPKEYIPAVQKGIEEAMQCGPLIGFPVVDIKVTLYDGCYHEV--DCCEMAFKIAGCMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNA-QVIRAFVPLAEMFG-YATDLRCKTQGRGCFVMFFDHYQEVPDPIADMLTRIRNATRVYKECTDV-PACRFKEEILRILAREGFIKGYERVDVDY--LRVYLKYG---PRRQGPDPRPEQVIHHIRRICKPGRRV---YVGVKEIPRVRRGLGIAILCTCKGVLTDREARKLGVGGELICEVW-MLAVGIVGLPNVGKCTLFNALTAGLV-KGAHKGEGLGNQFLA-HIREVALK-------ETPLLTALARAGYRALDLLTFFTAGEKE----VRAFIR-----AEVGKDYEVQD----GD???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????DAEGKTLGRLATKIAGDF-VVVVNADKIRVTGKKLEQKIYTR-YCGYPGGLKK-IPLEKMLATHPERVLEHAVKGMLP--KGPLGGKATPAPPVGPALGQHGANIMEFVKAFNAATANMG--DAIVP-VEITI--YADRCFTFVTKTPPACYLIRKAAGLEK------GAHKPGR-EKVGRITWEQVLEIAKQKMPDLNTTDLEAAARMIAGCARCMGVEVVGAP------EVKDAKVGMTRIFRDDR-----------AVPVTVILAGPCPVVQRRT-PEKDGYTAVQLGF--GDTVTV-EIFKPGERVDVTGTCKGRGFAGVMKRWNFAGGP-DCHGAHKIHRH-PGCIGNRKTPGRVYKGKKMAGHYGAERVTVMN------IPEENLLLVKGAVPGPNGGLVIVRETKKG-GVVPELACREHAATRGPGLIGALLVGYTFAKGMAFALDRPFYAVHHLEGHIAAA-WPE-----GLPPPFLALVACGGHTHLYEVLDLGRYRL-LGATRDDAAGEAFDKVARLLGLGFP----GGPEVERLAE------EA--EEAIPFPVPLRG--QEGYDFCFCGLKTEAAIAHLAEVVLKAGGVAANRALQERFKEA-----GLEVHFPPRGLCQDNGAMIALAAWRRHQRGRIKLRGFDHKTLDACAQKIVEAARRCGAQVCGPIPLPTRVRRFTVIRGPFK-HKDCREHFELRTHNRLVDIINPNRKTIEQLMTLDL---PTGVEIEI----LACPEKIRCWCYGEVEKPETINYRTLKPERDGLFDERIFGPIKDGKVCERCGVEVTKCIVRRYRMGHIELATPAAHIWFVKDVPCKIGTLLDLCATELPFEDDVEVCTHPCRARRAKARKRR----PEWMILEAVPVLPPDLRPMVQVDGGRFATCDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGA------PVTNPG-SDRPLRCLTDILCGKQGRFRQNLLGKRVDYCGRCVIVVGPQLKLHQCGLPKRMALELFKPFL--------LKKMEEKGIAPNV-----------ALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQCIQLHPLVCAFNADFDGDQMAVHVPLCCFAQAEARIQMLC-AHNLLCPACGEPLA--KPCRDIILGLYYITGRILFARIVADGYEMGFLT-------DRERYDQINPLYVMAQCGARGNPQQIRQLCGMRGLMQKP--------SGETFEV------------------PVRCCFREGLTVLEYFICCHGARKGGADTALRTADCGYLTRKLVDVTHE??????????????????????????????????????????????????????????????VKGPKGELEVPVCP--EMRVVVEEGV----VLTRTLIANAVKGVCEGYCKELLIKGIGY--RARLVGRA----LELTVGFCHPVVVEP--PEGITFEV---PEPTR-VRVCGIDKQKVGQVAANIGLDEAGRGAWAGPIVVGVVDCKLLCPRARERLAEKVDEKCPTVAAACILAKVHRDRIMAELDRLYPGYGNRIAAERVVARR--KGNLIPFLEHDDVRDCLAALYAEEDGEVAKVDGNRIVVRDGRLVE-YPLRRFYRCNQGTALDQRPVVVGQRVRKGDLLADGPACENGFLALGQNVLVAFDGYNFEDAIVICEELLKRDFYTCIHIERYEIEARDTKLGRITRDIP----------HLCEAALRDLDE-EGVVRIGAEVRLL----RCIFG-EK--ARDVKDTCPPGEGGIVVRTVVRVYVAQKRGDKLANRHGNKGVVAKILPVEDMPHLPNPLGVPCRMGQILETHLG-------LGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARCTGPYCLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKCDDI---------EGECFRVLVKELQALALDVQTDCGLEVYALGGEPGVYGCVEGVILEAPRGEG-GFGYDPLFYVP-------EAG--KTFAEMGLEEKKEAVARVFLRPGNGKVTVNNEYFQGLVRAVAALEPDAYITVRGGGKCGQIDAIKLGIARYRAKLKPLG--FLTRDARVVERKK--YGKHKARRAPQYCKRTLKLCPEA--FQRYYPEEARPGPLDLAAAPGGKTTHLAAHMGGKGLLLANEVDGKLFAPGVPEWGEGNGHLY--LLPEG---LPALLGLRAPAPGLYLG-KVQKGV-----------RE---PDRRELVDRF----YGAEPP---------IPREERFRLT----------------RRF------REEFPGGVAEVLARGYVPPKPLLLFDGLRGEGEVAYALEHLPRARFVLLHAREAT------RLKLVGPPGTGKTLLARAVAMRGKPIAE-------DVDAL-ELAHLTPGFCGADLRNLVNEARRAEVRQLQPDLVY----------------GDVLVTAFINKIMGKKNLAARIFYDACKIIQEKTGQEPLKVFKQAVENVKPRMEVRCRRVGGANYQVPMEVCPRRQQCLALRWLVQAAN----QRPERRAAVRIAHELMDAAEGK----GGAVKKKEDVERMAEANR?????????????????????????????????????????????????????????????????????????????????????????????------------------------MP----RCLKK----GIKTWCRRCTIVPEMVGHTIAVYNGKQHVPVYITENMVGHKLGEFAPTRTYRGHGKEAKATKKK-------ADNTGARKIMCIRVLK----GCNAKY--ATVGDVIVACVKEAIPRGAVKEGDVVKAVVVRTKKEVKRPDGCAIRFDDNAAVIINNQ-LE-PRGTRVFGPVARELREKGFMKIVCLA???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????------------------------------MPE-------TDFGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNG----------TIPHEIEVEFGACKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELG------SRNPINIAYATMEALGLLEKELYCAGLARVDIERA-ADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTG--KNVALNVQEV---QNPNLCAPLVAQRVAEQIERRFA-VRRAIKQAVQRVMEC-GAKGAKVIVCGRIGGAEQARTEWAAQGRVPLHTLRAN--IDYGFALARTTYGVLGVKAYIFLG--EVIGGQ?????????????????????????????????????????????????????HTGTLDPLATGLLLLVTNECTKLVPFLCGEDKEYFLEVREQVPPLYCAILGPRPVRYLEVEL--LGTYVRAFARDLGEMLGTKAFLCGLVRTRVGRVGLERA--VALP-------FPVVELCHTEARRVLEGMPLPIPAVTLVDCKRRLLKAFWCALQIPELRQRV-LFTLLVLAAYRLGAFIPTPGERFCIFALGIMPYITAAIIMQILVTVVPALEKLCKEG-EEGRRIINQYTRTQVA-GIALLLWMAERITEG-----IGNGTCLIIFAGIIVLAFAGMAAVQQAERRIPPIKLNAAGVIPIIFTYV--YTAVQ-FDP-KRIAECLREYGGFIPGIRPGEPTV-KFLEHIVCRLTLWGALFLGLVTLLPQII---QNLTGIQCIAFCGIGLLIVVGVALDTLRQVECQLMLRCYERRELPIVQVGP--------G---AVALLNLLGDTP--Y--VVARKTEKGKPQLLVLDGADIPRVRGKKVAIVDDVVCTGCTLAGLRELIECVG-LPTINQLVRKGREKV------------RKKCKVPALKGA------PFRRGVCTVVRTVTPKKPNCALRKAKVRL-TCGYEVTAYIPGEG--HNLQEHCVVLIRG-------GRVKDLPGVRYHIVRGVYDAAGVKDRKKCRCKYGTKKPKEEITVKELL-----EAGVHFGHERKRWNPKFAR--YIYAER--NGIHIIDLQKTMEELERTFRFIEDLAMRGGTILFVGTKKQAQDIVRMEAERAGMPYVNQRWLGGMLTNERLQKYLCGFRLLKRLPDAIFVVDPTKEAIAVREARKLFIPVIALADTDCDPDLVDYIIPGNDDAIRCIQLI---LCR-AVDLIIQAR???????????????????????????????????????????????????????????????????????????????????????????????KYVFITGGVVCCLGKGILTCCLGALLRARGYRVTAIKIDPYVNVDAGTMRPYEHGEVFVTAD--------G-----AETDLDIGHYERFLDMDLCRGNNLTTGQVYLCVIQKERRGEYLCQTVQVIPHITDEIKERIEIVVVEVGGTVGDIECLPFLEAIRQFRFDEGEGNTLYLHLTLVPYLETCEEFKTKPTQHCVATLRGVGIQPDILVLRCARPVPEEVRRKVALFTNVRPGHVFCCPTVEHLYEVPLLLEEQGMPDAYLCLLEALRHCGILVPGGFGVRGIEGKVRAAQYARERKIPYLGICLGLQIAVIEFARNVAGLKGANCTEFDPYTPHPVQLEV----EGLGGTMRLGDWPMRIKPGTLLHRLY-GKEEVLERHRHRYEVNPL-YVDGLERAG-----LVVCATTPGMRGRGAGLVEAIEL--KD--HPFFLGLQCHPEFKCRPMRPCPPFAKFDETVEVHAKL-GIDPRR-SDQNVRGTVCLPHGLG-KQVRVLAIAKGEKIKEAEEAGADYVGGEEIIQKILDGWM-------DFDAVVATPDVMGAVGCKL-GRILGPRGLLPIEFRNDKTGAIHAPVGKACFPPEKLADNIRAFIRALEAHKPEGAKGTFLRCVYVTTTMGMG--------RYIG-----PVCRLCRREGVKLYLK-GERCYCPKCAMERRPYPPGQHGQK--RARRPICERQFRNLFEEACKKKGVTGCVFLGLLECRLDNVVYRLGFAVCRRQARQLVRHGHITVNGRRVDLPCYRVRPGDEIAVILAPVLCEKAYAGFA-EGKYTFWVHPKATKTEIKNAVETAFKVKVVKVNTKKAIVQVAPGQ-----KIEALEG?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????WEVPRLEKVVINQGLGEAKEDARILEKAAQELALIT-GQKPAVTRAKKCICNFKLRKGMPIGLRVTLRRDRMWIFL-EKLLNVALPRIRDFRGLNPNCFDGRGNYNLGLREQLIFPEITYDMVDALRGRVACVGTLTLRIIYPTGVRLGLTELLFVTGPTGCGKTTTLYAALEQLYTK-EK-TFVTIEDPVEFPLEGVV-QIPVQPKIGL------TFAEALRTV--------LRLDPDVILVGEVRDAETLDTALRAALTGH-LVLATLHANDAIAALTRLL---EMGAERPL--LAATLIGTVAQRLVRRVCPQCARPMPV------PEEARLYLGERAPE-VEKRGV----GCPYC-R?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????AGALLTEVVEEVARHVEPGVCTWELDQIAYEAIR-KRKAKPA------FPATLCTCVNEVVVHGIP---SKEPLKEGDILCVDVGLIYQGFAADMARTLIRDTEAAFWEGMKYLRPGFRLGDVGHAIQTFLECRGYGVVREFVGHGVGR-EIHEDPQ-VPNGMTLALEPMVT--LRPAPVVILDDG--ACAGRGNLAAHYENTVLVTEEGPELLT----------------------MDG----------------------ELRAQGLRKRYGPKEVVRGVDLA-LRRGEIVALFGPNGAGKTTTFYMVVGFIRPT---------ITA---LPMYK--RAR-------------------------LGLG------------------------------YLPQEPCAF------------------------RRMTALENLLAVLE------------------------------------------------------------------------------------------FQPLC---------------KKERLEKAK------------LCGGERRRLEIARALATDPDFLLLDEPFTGVDPKNVREIQKVIAELRERRGVGVFITDH--------A
Uncultured_crenarchaeote_74A4                           ?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????RV?LTCICLPKLDTVCDEIMGIGKKTGVKVKGPTPLPVKRLHIATRKCPCGCGTETYEKWEMRMHRRIINI-SADDKAIRQLMRLKI---PDDVYIEL?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????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'Uncultured marine crenarchaeote KM3-34-D9'             ?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????RNFGVIAHVDHGKTTMCDCLLAHCGIIAP--SCAGTALALDYMKAEQERGITIVQANVTLHYKHDECE----YVINMIDTPGHVDFCGRVIRCLRAIDGAVVVCDAVEGIMTQTETVTRMALEERVRPVLFINKIDRLIKELRLTPEQMQERLAIVVTNFNTLLLGMVVKHHPPPHVAQKYRVPKIWKGDLDCDIGKAILNCDDNGPAIMMIVNMQLDPAAG-PIAIGRLFCGTLKDGQLVNIIDT-KREGRIQCVNFFMGNQREMVGELCAGNIPALLGLDDARAGQTEGIKYVCEPVVQMAIEPKHPKDLPKLVETLKRLTIEDPNLVIKIDEECGETIIAGMGVLHLEIATC-LI-HDAGLEIITCEPLINYRETVCVAC-EPIMAK------SPNRHNKIFMKVEPGVQFIDECCDCILTGFDDVMKEGPLAREQMRNCKFTFTHFVPHEDTAHRGLCQLGPACRRACLGCAILAKPVVLEPILGIEVRVPQDLVGNVACVICGKRGKVLDIQQKGIV-NIVIGEVPACETFD-LCQIMRGQTQGKAMWNTFFKCWCPIP???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????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;
END;

BEGIN CHARACTERS;
[! TreeBASE Matrix URI: http://purl.org/phylo/treebase/phylows/matrix/TB2:M8627]

	TITLE Archaea_rRNA;
	LINK TAXA = Taxa2;
	DIMENSIONS NCHAR=3719;
	FORMAT DATATYPE=DNA SYMBOLS= "A C G T" MISSING=? GAP= -;

MATRIX
[                                                               10        20        30        40        50        60        70        80        90        100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460       470       480       490       500       510       520       530       540       550       560       570       580       590       600       610       620       630       640       650       660       670       680       690       700       710       720       730       740       750       760       770       780       790       800       810       820       830       840       850       860       870       880       890       900       910       920       930       940       950       960       970       980       990       1000       1010       1020       1030       1040       1050       1060       1070       1080       1090       1100       1110       1120       1130       1140       1150       1160       1170       1180       1190       1200       1210       1220       1230       1240       1250       1260       1270       1280       1290       1300       1310       1320       1330       1340       1350       1360       1370       1380       1390       1400       1410       1420       1430       1440       1450       1460       1470       1480       1490       1500       1510       1520       1530       1540       1550       1560       1570       1580       1590       1600       1610       1620       1630       1640       1650       1660       1670       1680       1690       1700       1710       1720       1730       1740       1750       1760       1770       1780       1790       1800       1810       1820       1830       1840       1850       1860       1870       1880       1890       1900       1910       1920       1930       1940       1950       1960       1970       1980       1990       2000       2010       2020       2030       2040       2050       2060       2070       2080       2090       2100       2110       2120       2130       2140       2150       2160       2170       2180       2190       2200       2210       2220       2230       2240       2250       2260       2270       2280       2290       2300       2310       2320       2330       2340       2350       2360       2370       2380       2390       2400       2410       2420       2430       2440       2450       2460       2470       2480       2490       2500       2510       2520       2530       2540       2550       2560       2570       2580       2590       2600       2610       2620       2630       2640       2650       2660       2670       2680       2690       2700       2710       2720       2730       2740       2750       2760       2770       2780       2790       2800       2810       2820       2830       2840       2850       2860       2870       2880       2890       2900       2910       2920       2930       2940       2950       2960       2970       2980       2990       3000       3010       3020       3030       3040       3050       3060       3070       3080       3090       3100       3110       3120       3130       3140       3150       3160       3170       3180       3190       3200       3210       3220       3230       3240       3250       3260       3270       3280       3290       3300       3310       3320       3330       3340       3350       3360       3370       3380       3390       3400       3410       3420       3430       3440       3450       3460       3470       3480       3490       3500       3510       3520       3530       3540       3550       3560       3570       3580       3590       3600       3610       3620       3630       3640       3650       3660       3670       3680       3690       3700       3710         ]
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Aeropyrum_pernix_K1                                     GGTTGATCCTG-CCGGACCCGACCGCTATCGGGGTAGGGCTAAGCCATGGGAGTCGGCGGACGGCTGAGTAACACGTGGCTAACCTACCCTCGGGACGGGGATAACCCCTCGG-GAAACTGGGGCTAATCCCCGATAAGGGTCCTCCGCCGAAACGCCCGAGGATGGGGCTGCGGCCCATCACGGTAGTTGGCGGGGTAATGGCCCGCCAAGCCTACGACGGGTAGGGGCCGTGAGAGCGG-GAGCCCCCAGATGGGCACTGAGACAAGGGCCCAGGCCCTACGGGGCGCACCAGGCGCGAAAACTCCGCAATGCGGGCAACCGTGACGGGGCTACCCCGAGTGCTTTTCCCCGCTGTAAGAATAAGCGGGGGGCAAG-ACTGGTGTCAGCCGCCGCGGTAATACCAGCCCCGCGAGCGGTCGGGGTGCTTACTGGGCCTAAAGCGCCCGTAGCCGGCTCGACAAGTCCCCGCCTAAAGCCCCGGGCTCAACCCGGGGAGTGGC-GGGGATACTGTCG-GGCTAGGGGGCGGGAGAGGCCGAGGGTACTCCCGG-GGTAGGGGCGAAATCCATTAATCCCGGGAGGACCACCAGTGGCGAAGGCGCTCGGCTGGAACGCGCCCGACGGTGAGGGGCGAAAGCCGGGGGAGCGAACCGGATTAGATACCCGGGTAGTCCCGGCTGTAAACGATGCGGGCTAGGTGGTGCCGCAGGGAAGCCGTTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAAGGGGTGGA-GCCTGCGGCTTAATTGGAGTCAACGCCGGGAACCTCCACCGGGGGCGACAGCAG-GATGACGGCCGCTGAAGGCCTGAGGGGAGATGCATGGCCGTCGCCAGCTCGTGCCGTGAGGTGTCCTGTTAAGTCAGGCAACGAGCGAGACCCCCGCCCCTAGTTGCCAGGGGGGCACACTAGGGGGACTGCCGCCGC-TAAGGCG-GAGGAAGGAGGGGGCAACGGCAGGTCAGCATGCCCCTAAACCCCCGGGCTGCACGCGGGCTACAATGGCGGGGACAGCGGGTGCCGACCCCGAAAGGGGGAGGCAATCCCTCAAACCCCGCCTCAGTTGGGATCGAGGGCTGCAACTCGCCCTCGTGAACGTGGAATCCCTAGTAACCGCGCGTCATC-ATCGCGCGGTGAATACGTCCCTGCTCCTTGCACACACTGCCCGTCGCTCCACCCGAGGGGGCGAACCCCCTCCCCCCGAGGGGGGAGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGGCTCGGCTC-GGGCGCCGAGGAAGGGCGTGGCAAGCTGCGATAAGCCCGGGGTAGGCGC-AGGCAGCCGTCGAACCCGGGATCCCCGAATGGGACCCCCCGAAAGGAAGCATCTGAGTAGGGGGAGGAGAAGAAACCAACA-GGGA-TCCCCTGAGTAGGGGCGACCGAAAGGGGGA-GAGCCCAAACAGCCGAAG-TGGGCTGGAACGTAGAGGGTGATAGCCCCGTAGGCGAA-CAGAGTACCACGGCTTG---GTATTGCCGTGGGAAGCTGGGAGGAACC-GACTTCCAAGGCTAAATACGTCCCGA-GACCGATAGCGAACTAAGTACCGTGAGGGAAAGCTGAAAAGAACCCCG-GGAGGGGGGTG-AAAAGAGCCTGAAACCGGGCGGCGATCGCACCGTCCGTCTTGAAACACGGGCCGGGGAGTTCA-CGGCCGTGGCGA-GCTTAAGTAGGCGCAGGGAAACCGACAGGCCCGCAAGTCAC-GGCCGTGAGACCAGAAACCGGGCGATCTAGGCGGGGGCAGGGCGAAGCCGGG-GGAAACCCCGGTGGAGGCCCG--CAAGGGTGCTGACGTGCAAATCGCTCCCCTGACCCCCGTCTAGGGGTGAAAGGCCAATCTAGCCCGGAAGATAGCTGGTTCCCGCCGAAGTGGCTCGCAGGCCAGCCCCGCCGGAGGTAGAGCTACTGATTGGGGGGCGTAAAGCCCCCGGCGCCCAGTCAAACTCCGAAGG-AGTGGGGTTCCCC-GGGGTAAGCCCGGG-GGCCGAGAG-GGGAACAACCCAGACCGG-GGTTAAGGCCCCTAAGTGCCGGCT-AAGTGCC--AAGCCAAAGGGCGTCCCCCGCCTAAGACAGCGGGGAGGTGGGCCTAACAGCAGCCA-TCCTCTAAGGAGTGCGTAACAGCTCACCCGCC----GAGGCGGGGGGCCCCGAAGATTGGTCGGGGCTTAAGCCGGCCGCCGAGACCCCGGGTAGGCGG-GCGTCGGG-GTGGCGTAGAAGCC-GGGCCGCGAGGTCCGGTGGAGCGGATCCCGGCGGTAGTA-ACAGCG-AAGCGGGGTGAGAATCCCCGCCGCCGGAAAGGGC-AAGGGTTCCCC-GGCAATG-GTCGTCAGCCGGGGGTCAGCCGGTC--CTAACCGGGACCG--AAGGGGAAACGGGTTAACATTCCCGTGCCCGCCTCGGGGTAG-GGGAGTGCCGTACGGCGAGAACCGGCC-GAAACCCCTGGGGCCCTTGAAACGTACCGAGAACCGACACAGGTGCCCCTGGGTGAGCA-GCCCAAGGCGTCTGGGGGCTAACCCG-GGCCAGGGAACTCGGCAAATTGGCCCCGTAACTTCGGGAGAAGGGGTGCCGCAGGTCGCAGTGCCTAGGGGGGCCTGACTGTTTAACAAAAACATAGCTCCCCGCTAGCCCGAAAAGGGTGTGTACGGGGGGTGAGCCCTGGCCACTGGCGGTCCGTGAAACCGGGGTACAAAAGCGCCGCTGAAGGCCGGGAGTAACCCTGACTCTCTTAAGGTAGCCAAATGCCTTGCCGGGTAAGTTCCGGCGCGCATGAACGGGTCAACGAGGTCCCCACTGTCCTGGCCCGGGGCCCCGTGAACCCCC--TGAGCCGATGCACAGTCCGGCATCCCCCCGCAGGGAGAGAAGACCCCGTGGAGCTTTACCGCAGCCCGGCGTTGGGCGGGGGTGCGTAGCGTAGGTGGGAGCCGATG---AGAGGCGTCCATGAAACACCACCCGACAGCGTCGGGTGGGCGGTTTGGCTGGGGCGGCACGCCCGCGAAAGGGTAACACGGGCGCCCAAAGGTCGGCTCAGGCGGGTCAGAACTCCGCCGTAGAGTG-CAAGGGCAAAAGCCGGCCTGACCGGACCCCTGAAAGCAAGGGGTCCGGCCGGGAAACCGTGGCCTAGCGCACGCTCGTG---CCCCCTCGGTGGGGGCCGGGCACGACAGA--AAAGTTACCCCGGGGATAACAGAGTCGTCGCGGGCGAGAG-CCCCCATCGACCCCGCGGTTTGCTACCTCGATGTCGGCTCTTCCCATCCTGGGGGTGCAGCAGCCCCCAAGGGTGGGGCTGCCCGCCCATTAAAGGGGAACGTGAGCTGGGTTCAGACCGTCGTGAGACAGGTCGGTCTCTACCCGCGGGGGGTGTG-GGCCGCCTGAGGGGAAGGTGCCCTTAGTACGAGAGGAACGGGGCGCCGCGGCCTCTGGTGTACCGGTTGTCGGCA-ACGCCGGGCAGCTAAGCCGTAGGGGG-TAACCGCTGAAAGCATCTAAGCGGGAACCCCTCCCCGAA-AAGAGGCGGCAGGGC-TCCCGTAGAAGACGGGGTTGATGGGGCGGGGGTGTGAGGGGTGTAGCCCGCCGCTCCCAA
Agrobacterium_tumefaciens                               GTTTGATCCTGGCTCAGAACGAACGCTGGCGGCAGGC--TTAACACATGCAAGTCGGCAGACGGGTGAGTAACGCGTGGG-AACATACCCTTTCCTGCGGAATAGCTC--CGG-GAAACTGGAATTAATACCGCATA-CGCCCTACGGGGGAAACGGGGAAGGATTGGCCCGCGTTGGATTA-GCTAGTTGGTGGGGTAAAGGCCTACCAAGGCGACGATCCATAGCTGGTCTGAGAGGAT-GATCAGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGCAAGCCTGATCCAGCCATGCCGCGTGGCTCTTTC-ACCGGAGAAAGAAGCCCCGGCTAAC--TTCGTGCCAGCAGCCGCGGTAATACGAAGGGGGCTAGCGTTGTTCGGAATTACTGGGCGTAAAGCGCACGTAGGCGGATATTTAAGTCAGGGGTGAAATCCCAGAGCTCAACTCTGGAACTGCC-TTTGATACTGGGT-ATCTTGAGTATGGAAGAGGTAAGTGGAATTCCGAG-TGTAGAGGTGAAATTCGTAGATATTCGGAGGAACACCAGTGGCGAAGGCGGCTTACTGGTCCATTACTGACGCTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGAATGTTAGCCGGTGGCGCAGCTAACGCATTAAACATTCCGCCTGGGGAGTACGGTCGCAAGATTAAAACTCAAAGGAATTGACGGGGGCCCGC-ACAAGCGGTGGA-GCATGTGGTTTAATTCGAAGCAACGCGCAGAACCT-TACCAGCTCTTGACATTC----GGGGTTTGGAGACATTGTAACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTCGCCCTTAGTTGCCAGTTGGGCACTCTAAGGGGACTGCCGGTGA-TAAGCCGAGAGGAAGGTGGGGATGACGTCAAGTCCTCATGGCCCTTACGGGCTGGGCTACACACGTGCTACAATGGTGGTGACAGTGGGCAGCGAGACAGCGATGTCGAGCTAATCTCCAAAAGCC-ATCTCAGTTCGGATTGCACTCTGCAACTCGAGTGCATGAAGTTGGAATCGCTAGTAATCGCAGATCAGC-ATGCTGCGGTGAATACGTTCCCGGGCCTTGTACACACCGCCCGTCACACCATGGGAGTTGGCCACGGTAGGGTCAGCGACTGGGGTGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCT--------------------------------------------------------------------------------------------------ACGCAGGGAACTGAAACATCTAAGTACCTGCAGGAAAGGACATCAACC-GAGA-CTCCGCAAGTAGTGGCGAGCGAACGCGGAC-CAGGCCAG--AAGCGGAA-CGATTTGGAACATAGAGGGTGATAGCCCCTTACGCGTACTTGAGTAGGGCGGGACACGTGAAATCCTGTCTGAACATGGGGAG-ACC-ACTCTCCAAGCCTAAGTACTCGTGCATGACCGATAGCGAACA-AGTACCGTGAGGGAAAGGTGAAAAGCACCCCGACGAGGGGAGTGAAATAGAACCTGAAACCGGATGCCTATGACGGCGTACCTTTTGTATAATGGGTCAACGACTTA-GTGTAACTAGCAA-GCTTAAGTAGGCGCAGCGAAAGCGAG-TCTGAATAAGTTAGTTGCATTA-GACCCGAAACCGAGTGATCTAGCCATGAGCAGGCTGAAGGTTGG-GTAACACCAACTGGAGGGCCG---AACCCGTATCTGTTGCAATAGATTGGGATGACTTGTGGCTAGGGGTGAAAGGCCAATCAAACTCGG-AAATAGCTGGTTCTCCGCGAAATCTATTTAGGTAGAGCGTCGAC-CGAGTAGAGC-ACTGGATGGGGACTCACCGTCTTACTGATCCTAACCAAACTCCGAAGGCAGACACACGGCGG-GTGCTAACGTCCGT-CGTGAAAAG-GGCAACAACCCTGACCTCCAGCTAAGGTCCCCAAGTCATGGCT-AAGTG-------GGAAAGGATGTGAGGATCCCAAAACAACCAGGATGTTGGCTTAGAAGCAGCCA-TCATTTAAAGAAAGCGTAACAGCTCACTGGTCTAAATAAGGGTCTTGCGCCGAAAATGTAACGGGGCTAAAGCCATGCACCGAAGCTGAGGGTAGCGGA-GCGTTCCGTAAGTCTGTGAAGGCGGACCCGTGAGGGCTGCTGGAGCGAATGTTGACATGAGTA-ACGATA--AAGGGAGTGAGAGACTCCCTCGCC-GAAAGACC-AAGGGTTCCTG-CTTAAAG-TTAATCTGAGCAGGGTTAGCCGGCC-CCTAAGACGAGGCGTCGATGGGAACCACGTTAATATTCGTGGGCCCGGA----------T--------------GGTTGTGCGGC--GAA---------TTCCAGGAAACGTACCCGAAACCGACACAGGTGGTCAGGTA-GAGTA-TACCAAGGCGC-TTGAGAGAACTATG--TTGAAGGAACTCGGCAAATTGCACGCGTAACTTCGGAAGAAGCGTGACCTGGGGTGGCACAGACCAGGGGGTAGCGACTGTTTATCAAAAACACAGGGCTCTGCGAAGTAG-CAATACGACGTATAGGGTCTGACGCCTGCCCGGTGCTGGAAGGTTAAAGGGAGGGGTGCAAGCCCCAGTAAACGGCGGCCGTAACTATAACGGTCCTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCTGCACGAATGGCGTAACGACTTCCCCGCTGTCTCCAACATAGACTCAGTGAAATTGA--ATTCCCCGTGAAGATGCGGGGTTCCTGCGGTCAGACGGAAAGACCCCGTGCACCTTTACTATAGCTTTACACTGCCAAGGCATGTGTAGGATAGGTGGTAGGCTTTG---AGAGCCATCCTTGAAATACCACCCGACAGTGTATGGTGGGTAGTTTGACTGGGGCGGT-CGCCTCCGAAAGAGTAACGGAGGCGCGCGATGGTTAGCTCAGACCGGTCGGAAATCGGTCGTCGAGTG-CAATGGCATAAGCTAGCCTGACTGCGAGACTGA---CAAGTCGAGCAGAGACGAAAGTCGGTCATAGTGATCCGGTGGTC---CCGTGTGGAAGGGCCATCGCTCAACGGATAAAAGGTACGCCGGGGATAACAGGCTGATGACCCCCAAGAG-TCCATATCGACGGGGTTGTTTGGCACCTCGATGTCGACTCATCGCATCCTGGGGCTGGAGCAGGTCCCAAGGGTATGGCTGTTCGCCATTTAAAGCGGTACGTGAGTTGGGTTCAGAACGTCGTGAGACAGTTCGGTCCCTATCTGCCGTGGGTGTA-GGAATATTGACAGGA-TCTGTCCCTAGTACGAGAGGACCGGGATGGACGTATCTCTGGTGGATCTGTTGTCGGCAT-AGCAGAGTAGCTATATACGGAATGGATAACCGCTGAAGGCATCTAAGCGGGAAACCAACCTGAAA-ACGAGTGTTCCAGAGCCGTGGAAGACGACCACGTTGATAGGACGGGTGTGGAATGTGTGAAGCTTACCGTTACTAA
Anaeromyxobacter_dehalogenans                           -TTTGATCCTGGCTCAGAACGAACGCTGGCGGCGTGC--CTAACACATGCAAGTCGGCGCACGGGTGCGTAACACGTGGGTAATCTGCCCTAGAGTCCGGAATAACTC--GCC-GAAAGGCGTGCTAATGCCGGATGGGCTCCTGCGGGAAAAGCGCTCTAGGATGAGCCCGCGGCCCATCA-GCTCGTTGGCGGGGTAATGGCCCACCAAGGCAACGACGGGTAGCTGGTCTGAGAGGAC-GATCAGCCACACTGGAACTGAGACACGGTCCAGACTCCTACGGGAGGCAGCAGTGGGGAATCTTGCGCAATGGGCGAAAGCCTGACGCAGCAACGCCGCGTGGCACTGTC-GCGAGGGAAGGAAGCACCGGCTAAC--TCTGTGCCAGCAGCCGCGGTAATACAGAGGGTGCGAGCGTTGTTCGGAATTATTGGGCGTAAAGCGCGTGTAGGCGGCCTAGCAAGTCGGATGTGAAAGCCCTCGGCTTAACCGAGGAAGTGCG-TTCGAAACTACTG-GGCTTGAGTACCGGAGAGGGTGGCGGAATTCCCGG-TGTAGAGGTGAAATTCGTAGATATCGGGAGGAACACCAGTGGCGAAGGCGGCCACCTGGACGGATACTGACGCTGAGACGCGAAAGCGTGGGTAGCAAACAGGATTAGATACCCTGGTAGTCCACGCTGTAAACGATGAGCGCTAGGTGGTGCCGCAGCTAACGCATTAAGCGCTCCGCCTGGGAAGTACGGCCGCAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGC-ACAAGCGGTGGA-GCATGTGGTTTAATTCGACGCAACGCGCAGAACCT-TACCTGGTCTTGACATCCTCG-GAATCCCGATGAGGGGGTGACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCCTGCCGTTAGTTGCCAGTTGGGCACTCTAACGGGACTGCCGGCGT-CAAGCCG-GAGGAAGGTGGGGATGACGTCAAGTCCTCATGGCCTTTATGACCAGGGCTACACACGTGCTACAATGGCCGGTACAGAGGGTCGCCAAGTCGCGAGACGGAGCTAATCCCAGAAAACCGGTCTCAGTTCGGATTGGAGTCTGCAACTCGACTCCATGAAGTCGGAATCGCTAGTAATCGCGGATCAGC-ACGCCGCGGTGAATACGTTCCCGGGCCTTGTACACACCGCCCGTCACACCATGGGAGTCAGCTAAGGAGTGGCTGGTAACTGGGGTGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGCCTTGGCTCTAGGAGGCGACGAAGGACGTGGGTAGCTGCGATAAGCTACGGGGAGCCGCTAACCAGGCTTTGATCCGTAGATTTCCGAATGGGACCCGGGGAAGTGAAACATCTCAGTACCCGGAGGAAAAGAAAGCAAACAGCGA-TTCCGTCAGTAGTGGCGAGCGAACGCGGAACTAGCCCAAACAGGTG-AG-CCGTCTGGAACACAGAGGGTGACAGTCCCGTAACCGAACCCAAGTAAGGCGGGACACGTGTAATCCTGCCTGAATCTGCGAGG-ACC-ATCTCGTAAGGCTAAATACTACCTAGAGACCGATAGTGAACA-AGTACCGCGAGGGAAAGGTGAAAAGAACCCCTGTTAGGGGAGTCAAA-AGAACCTGAAACCGCATGCCTATGAGGGCGTACCTTTTGCATCATGAATCGGCGACTTAATGGTT-GTGGCGA-GCTTAAGGAGGCGCAGCGAAAGCGAG-TCCGAAACAGTCGCAATCATTATAACCCGAAGCCAGGTGATCTACTCATGGCCAGGTTGAAGCGCGG-GTAAAACCGCGTGGAGGACCG---AACTCATGGAGGTTGAAAACTTCTGGGATGAGCTGTGAGTAGGGGTGAAAGGCCAATCAAACTTGG-TGATAGCTGGTTCTCCCCGAAAGATATTTAGGTATCGGCTCGGGAAATGTAGAGC-ACTGGAACGGTCCT-ACCAGATTACCAACCCGTACCAAACTCCGAAGGGACGCAGTCGGTGG-GTGATAACATTCAT-CGGCGAGAG-GGGAATAACCCAGATCGTCGGCTAAGGTCCCAAAGTCCATGCT-AAGTGAT--CACAAAAAGGATGTGGTAGCGCTTTGACAATCAGGAGGTTGGCTTAGAAGCAGCCA-TCCTTTAAAGATAGCGTAATAGCTCACTGATC----AAGCGAGACTGCGCCGAAAATGTATCGGGTCTCAAGCATGGCACCGAAGCCACGGGTAGGGGA-GCATAGAA-CGGACGGTGAAGCCAG-ACCGCAAGGACTGGTGGAGCTGATGCCGATATGAGTA-GCGACA--AAACGAGTGAGAAACTCGTTCGCC-GTAAGCCC-AAGGTTTCCTG-GGGAAGG-TTAATCCGCCCAGGGTTAGTCGGGC-CCTAAGCCGAGGCGGTGATGGACAACAGGTTAATATTCCTGTACCCGGAGAAGGGTAG-CGTGACGCCGT-TAACGCCGAGAGGT--GATATCCCATGCTTCCTAGAAACGTACCGCAAACCGACTCAGGTGGGCGAGGA-GAAAA-TCCTAAGGCGC-TTGAGAGAACTCTG--GTCAAGGAACTCTGCAATTTTCCACCGTAACTTCGGAAGAAGGTGGGCCCTGGGTCGCAGCGAAATGGCGGTAGCGACTGTTTAACAAAAACACAGGACTCTGCAAACACGTCAAGTGGATGTATAGGGTCTGACGCCTGCCCGGTGCCGGAAGGTTAAGGAGATTCGTCAAAGCCCCGGTAAACGGCGGCCGTAACTATAACGGTCCTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCTGCACGAAAGGCGTAACGACTTCCGCGCTGTCTCGACCAGGGACTCAGCGAAATTGA--AATAGCTGTGCCGATGCAGTTTACCCGCGGCAAGACGGAAAGACCCCATGAACCTTTACTACAACTTGCCACTGGAATTGATTGTGTAGGATAGGTGGGAGCCTATG---AGAGGCAACGGTGAAATACCACCCGACAATGGCTGGTGGGTAGTTTGACTGGGGCGGT-CGCCTCCCAAAAGGTAACGGAGGCGCGCTATGGTTCCCTCAGCCTGATTGGAAACCAGGCGTCGAGTG-CAATGGCATAAGGGAGCTTGACTGCGAGACCGA---CAGGTCGAGCAGGTGCGAAAGCAGGTCATAGTGATCCGGTGGTT---CTGTATGGAAGGGCCATCGCTCAACGGATAAAAGGTACTCTGGGGATAACAGGCTTATCGCGTCCAAGAG-TTCACATCGACGACGCGGTTTGGCACCTCGATGTCGGCTCATCGCATCCTGGGGCTGGAGCAGGTCCCAAGGGTTTGGCTGTTCGCCAATTAAAGCGGTACGCGAGCTGGGTTCAAAACGTCGTGAGACAGTTTGGTCCCTATCTGCCGTGGGCGTA-GGAGAAGTGAGAGGA-TCTGTCCTTAGTACGAGAGGACCGGGATGGACGCACCGCTGGTGTACCAGTTGTCGGCAT-CGCTGGGTAGCTATGTGCGGAACGGATAACCGCTGAAAGCATCTAAGCGGGAAGCCAACCTCAAG-ACGACTTCTCAAGCCCCCTCGAAGACGACGAGGTCGATAGGCCGGAGGTGTAAGGCGCTCAGCTGACCGGTACTAA
Aquifex_aeolicus                                        GTTTGATCCTGGCTCAGCGCGAACGCTGGCGGCGTGC--CTAACACATGCAAGTCGGCAAACGGGTGAGTAACACGTGGGTAACCTACCCCCAGGAGGGGGATAACCC--CGG-GAAACCGGGGCTAATACCCCATAAGGCGCGGTGGCCAAAGCGCCTGGGGATGGGCCCGCGGCCCATCA-GGTAGTTGGTGGGGTAACGGCCCACCAAGCCTATGACGGGTAGCCGGCCTGAGAGGGT-GGCCGGCCACAGCGGGACTGAGACACGGCCCGCACCCCTACGGGGGGCAGCAGTGGGGAATCGTGGGCAATGGGCGAAAGCCTGACCCCGCGACGCCGCGTGCCCCTGTC-GGGGGGGAAGGAAGGGACGGCTAAC--TACGTGCCAGCAGCCGCGGTAATACGTAGGTCCCAAGCGTTGCGCGAAGTCACTGGGCGTAAAGCGTCCGCAGCCGGTCGGGTAAGCGGGATGTCAAAGCCCACGGCTCAACCGTGGACCGGCA-TCCCGAACTGCCC-GACTTGAGGCACGCCCGGGCAGGCGGAATTCCCGG-GGTAGCGGTGAAATGCGTAGATCTCGGGAGGAACACCGAAGGGGAAGCCAGCCTGCTGGGGCTGTCCTGACGGTCAGGGACGAAAGCCGGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCCGGCCGTAAACCATGGGCGCTAG---GGCTCGCAGCTAACGCGTTAAGCGCCCCGCCTGGGGAGTACGGGCGCAAGCCTGAAACTCAAAGGAATTGGCGGGGGCCCGC-ACAACCGGTGGA-GCGTCTGGTTCAATTCGATGCTAACCGAAGAACCT-TACCCGGGCTTGACATGCCGGGGAGACTCGTTGTGGAAGTCACAGGTGGTGCATGGCCGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCCTGCCCCCAGTTGCTAGG-GAGCACTCTGGGGGGACCGCCGGCGA-TAAGCCG-GAGGAAGGGGGGGATGACGTCAGGTCAGTATGCCCTTTATGCCCGGGGCCACACAGGCGCTACAGTGGCCGGGACAATGGGATGCGACCCCGTAAGGGGGAGCTAATCCC-TAAACCCGGTCATGGTGCGGATTGGGGGCTGAAACTCGCCCCCATGAAGCCGGAATCGGTAGTAACGGGGTATCAGCGATGTCCCCGTGAATACGTTCTCGGGCCTTGCACACACCGCCCGTCACGCCACGGAAGTCGGCGATGGCCGGGCCGGCGACTGGGGCGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGCCTCGGCTCCCGGAGCCGATGAAGGGCGTGCAAAGCTGCGATAAGCCGGGTGGAGGCGC--AAGAGCCGTTGAGGCCCGGATGCCCGAATGGGACCGGCCGAAGCAAAACCTTTTAGTAGGCCGAGGAAAGGAAATCAATT-GAGA-CGCCCTGAGTAGCGGCGAGCGAAAGGGGCT-CAGCCCAAACAGCCGAAG-TCCCCTGGAACATAGAGGGTGAAAGCCCCGTAGGCGAACCCAAGTACCGCGGCCCACGTGAAAGGTCGCGGGAATCCGGGGGG-ACC-ACCCTCCAAGGCTAAGTACTCCCGGGAGACCGATAGCGCAT--AGTACCGTGAGGGAAAGGTGAAAAGAACCCCTGG-CGGGGAGTGAAATAGAACCTGAAACCCCGGGTCCACGACTGCGTGCCTTTTGCAGAATGAGCCGGGGAGTTG-TCCTCAGGGGCGA-GGCTAAGAAGCCGTAGCGAAAGCGAG-TCCGAATAAGTCCCTGGGGGCA-GACGCGAAGCCGGGCGATCTACCCTTGCCCTGGGTGAAGGCCGG-GTAACACCGGCTGGAGGCCCT---AAGGGGTCGGTGCTGCAAAACCGTCCCGTGAGGTGAGGGTAGCGGTGAAAAGCCAATCGCGCCCGG-GGATAGCTCGTTCTCCCCGAAATGCATCGAAGTGCAGCGTCGCC-CGTGTAGAGC-ACTGCTGGGGCCCCGAAAGGGGTACCGAACCCCGGCAAACTCCGAAGGCAGTGAGTCCTCGG-GGGATAAGCTCCGA-GGACAAGAG-GGAAACAGCCCAGACCGCCGGCTAAGGCCCCAAAGTCCGGGCT-AAGTG-------GTAAAGGAAGTCCCCGTCCTAAGACAGCCGGGAGGTTGGCTTAGAGGCAGCCA-TCCTTTAAACAGTGCGTAACAGCTGACCGGTC----GAGGGCGGGGGCGCCGAAAATTTAGCGGGGCTTAAGCCCGGCGCCGAAGCCGCGGGTAGGGGA-GCGTTCCC-AGCGCGCTGAAGCCCAAGCCGTGAGGCAGGGTGGAGAGAATCCCGGCATGAGTAGGAGCGA--AGGCAGGTGAGAAACCTGCCCGCC-GGAAGCCC-AAGGGTTCGGC-GGCAATG-GAAATCAGCCGCCGGTTAGCCGGGACCCTAAGGCGAGGCGCCGATGGGAAGCGGGTCAACATTCCCGCGCCCGCAGGAGGCTAG-GGCAAATCCGTATA-CCCCGAGAGCC--GATACGCCACACTGCCAAGAAACGTACCGGAAACCGACACAGGTGGGCTGGGT-TAGGA-GCCTAAGGCG--TCGGGGGAACTCCC--CTCAAGGAACTCGGCAAGTTGGCCCCGTACCTTCGGAAGAAGGGGTGCCGTGGGTCGCAGTGACAGGGCGGTGCCGACTGTTTACCAAAAACACAGGACTACGCAAACCCG-AAAGGGGATGTATGTGGTCTGAAGCCTGGCCAGTGCCCGAAGGTGAAGGCCCCCGGTGAAAGCCCGGGTAAACGCCGGCCGTAACTATGACGGTCCTAAGGTAGCGAAATTCCTTGCCGGGTAAGTTCCGGCCTGCATGAATGGCCCAACGAGTGCCGCACTGTCTCGAGGGGAGTCCCGCCGAAATTGT--AATGCCGGTCAAGATGCCGGCTACCCGCGGCAGGACGGAAAGACCCCGTGAAGCTTCACTGCAGCCTGGCATTGGCCTGTCCTGCGCAGGATAGGTGGGAGCCTGGG---AGAGGCGCCGGTGAGATACCACCCGACAGTGCTAGGTGGGCAGTTTAGCTGGGGCGGC-TGCCTCCTAAAGAGTAACGGAGGCGCCCAAAGGTCCCCTCAGGCGGGTCGGAAATCCGCCGTAGAGTG-CAAGGGCATAAGGGGGCCTGACTGTGAGGCCGA---CGGGCCGAGCAGCCGCGAAAGCGGGGCCTAGTGACCCACCCGCT---CCACGTGGGAGGGCGGGTGATCAGCGGATAAAAGCTACTCCGGGGATAACAGGCTAATCGCCCCCGAGAG-CCCACATCGACGGGGCGGTTTGGTACCTCGATGTCGGCTCCCCCCATCCTGGGGCTGAAGCAGGTCCCAAGGGTTGGGCTGTTCGCCCATTAAAGGGGGACGCGAGCTGGGTTCAGAACGTCGCGAGACAGTTCGGTCCCTATCCGCCGCGGGCGCA-GGAGCCTTGAGGGGG-TCCGTCCCTAGTACGAGAGGACCGGGACGGGGCAGGCACTGGTGTACCGGTTGTCGGCAG-CGCCGGGTAGCCATCCTGCTACGGGATAAGCGCTGAAAGCATCTAAGCGCGAAGCCCACCCCAAG-ATAAGGGCTCAAGGGCCCCGGGAGACTACCGGGTTGATAGGCCGCAGGTGGAAGGGGTGAAGCCGAGCGGTACTAA
Archaeoglobus_fulgidus_DSM_4304                         GGTTGATCCTG-CCAGAGGCCGCTGCTATCCGGCTGGGACTAAGCCATGCGAGTCGGCGGACGGCTCAGTAACACGTGGACAACCTGCCCTCGGGTGGGGGATAACCC--CGG-GAAACTGGGGCTAATCCCCCATAATGTCCCATCTCCGAAACGCCCGAGGATGGGTCTGCGGCGGATTA-GGTTGTTGGTGGGGTAACGGCCCACCAAGCCGAAGATCCGTACGGGCCATGAGAGTGG-GAGCCCGGAGATGGACCCTGAGACACGGGTCCAGGCCCTACGGGGCGCAGCAGGCGCGAAACCTCCGCAATGCGGGAAACCGCGACGGGGTCAGCCGGAGTGCTGTCGGGGTGCCTAAAAGCAAGGGCCGGGCAAG-GCCGGTGGCAGCCGCCGCGGTAATACCGGCGGCCCGAGTGGCGGCCACTTTTATTGGGCCTAAAGCGTCCGTAGCCGGGCTGGTAAGTCCTCCGGGAAATCTGGCGGCTTAACCGTCAGACTGCCGGAGGATACTGCCA-GCCTAGGGACCGGGAGAGGCCGGGGGTATTCCCGG-AGTAGGGGTGAAATCCTGTAATCCCGGGAGGACCACCTGTGGCGAAGGCGCCCGGCTGGAACGGGTCCGACGGTGAGGGACGAAGGCCAGGGGAGCGAACCGGATTAGATACCCGGGTAGTCCTGGCTGTAAACGATGCGGACTAGGTGGTGCCGGAGGGAAGCCGTTAAGTCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACTACAACGGGTGGA-GCCTGCGGTTTAATTGGATTCAACGCCGGGAAGCT-TACCGGGGGAGACAGCGG-GATGAAGGTCGCTGAAGACCTGAGAGGTGGTGCATGGCCGCCGTCAGTTCGTACTGTGAAGCATCCTGTTAAGTCAGGCAACGAGCGAGACCCGCGCCCCCAGTTGCCAGCCGGGCACACTGGGGGGACTGCCGGCGC-TAAGCCG-GAGGAAGGTGCGGGCAACGGCAGGTCCGTATGCCCCGAATCCCCCGGGCTACACGCGGGCTACAATGGCCGGGACAATGGGTACCGACCCCGAAAGGGGTAGGTAATCCCCTAAACCCGGTCTAACCTGGGATCGAGGGCTGCAACTCGCCCTCGTGAACCTGGAATCCGTAGTAATCGCGCCTCAAA-ATGGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCAAGCCACCCGAGTGGGCGAGCCCAGGGTCCGCGAGGGGGGCTAAGTCGTAACAAGGTAGCCGTAGGGGAATCTGCGGCTGGATCACCTGGATGGCTCGGCTC-GGGCGCCGACGAAGGGCGTGCCAAGCTGCGAAAAGCCCGGGGGAGGCGC-AAGGAGCCTTAGAACCCGGGATTCCCGAATGGGACGCGGGGAAAGGAAACATCTGTGTACCCGCAGGAAAAGAAAGCAAAC-GCGA-TGCCGTGAGTAGGGGCGACCGAAAGCGGCA-CAGCCCAAACAGCCGAAG-TGGTCTGGAACGTAGAGGGTGATAGCCCCGTAGGCGTACCTGAGTACCGTGGGTTG---GAATTCTCGCGGGAAGCTGGGGGTCATC-AACCCCCAAGGCTAAATACGTCCCGA-GTCCGATAGCGCAAT-AGTAGGGTGACCGAAAGCTGAAAAGAACCCCGAGAAGGGGAGTG-AAAAGAGCCTGAAATCGGCCGGGGATCACTGCGTACGTTCTGAAGAACGGGCCAGGGAGTGTA-CGGCAGGGGCGA-GGCTAAGAAGCCGGAGGGAAACCGAC-AGCCCGCAAGTCCC-TGCCGTACGACCCGAAGCCGGGCGATCTAGGCGGGGGCAGGGTGAAGCGGTG-CGAAAGCGCCGTGGAGGCCCG--CAGGGGTGTTGATGTGCAAATCGCTCCTCTGACCCCCGTCTAGGGGTGAAAGTCCAATCGAGCCCGG-GGATAGCTGGTTCCCCCCGAGACATACCGCAGTATGACCCGTCCGGAGGTAGAG-CACTGATAGGGGGGTG--ACACCCTCGCCCTCCTGTCAAACTCCGAAGG-AGTCAGGGGCAG--GGGGTAAGCTCCTG-TTCCGAGAG-GGAGACAACCCAGACCGG-GGTTAAGGCCCCTAAGTGCCGGCT-AAGTGTA-AACGATAAAGGAGGTCCCGGGTCGAAGACAGCGGGGAGGTAGGCTTAGAAGCAGCCA-CCCTTTAAAGAGTGCGTAACAGCTCACCCGCC----GAGACTCGGGGCGCCGAAAATGGAC-GGGGCTCAAGCCGGCCGCCGATACCCCGGGTAGGGGG-GCGTGCCG-ATGGCGCAGAAGCCTGAGGCGTAAGCTCGGGTGGAGAATATCCTGGCGGTAGTA-GCAGCA-TAGTCGGGTGAGAATCCCGACCGCC-GGAAGGGC-AAGGGTTCCAC-GGCAATG-TTCGTCAGCCGTGGGTGAGTCGGTC--CTAAGGTGGCCCGA-AAAGGGAAGCCGGTTAATATTCCGGCACCCGCCTCGGGATAG-GGGAGATCCGTATGGAGAGAAGGGGGT-GAAACTCCTGGGGCCCGTGAAACGTACCGAGAACCGACACAGGTGCCC-TGGGTGAGTA-GCCTAAGGCGTGGCGGAAC-ATTCCG-GCCGAGGGAATTCGGCAAGTTGGCCCCGTATCTTTGGTAGAAGGGGTGCCGCAGGTCGCAGTGACTAGGGGGGAGCGACTGTTTACTAAAAACACAGGGGGCTGCAATCCGG-CAACGGTTTGTACAGCCCCTGAGTCCTGCCCAGTGCGGGTACCTGAAACCAGGGTACAAAAGGGCCCGTAAACGGCGGGGGTAACTATGACCCTCTTAAGGTAGCGTAATACCTTGCCGCTTAATTGGCGGCTTGCATGAACGGATTAACGACTCCCCCACTGTCCCCGGCCGGAAGCCGGCGAACCCGA--CATCCCAGTGAAGAGTCTGGGGACCCCCGTTGGGAAGCGAAGACCCTGTGGAGCTTTACTGCAGCCTGCCGTTGGCTGGGGGTGCGCAGGGTAGGCGGGAGGCTTCG---AGAGCCGTCGATGAGACACCGCCCGACATCGGTAGGTGGGCAGTTTGGGTGGGGCGCCACTCCCCCGAAAAGGTATCGGGGGAGCCCAAAGGTCGGCTCAGGCGGGTCAGAAATCCGCCGTAGAGTG-CAAGGGCAAAAGCCGGCCTGACGTGAACCCGCAAAATAAGGGTTCACGAGCCGAAAGGCGGGCCTAGCGAACCACCCTG---GCCTTTTGGTGAGGCCGGGTGACGACAGA--AAAGCTACCCCAGGGATAACAGAGTTGTCCCCGGCGAGAG-TACATATCGACCCGGGGGCTTGCTACCTCGATGTCGGCTCTCCCCATCCTGGCCGTGCAGCAGCGGCCAAGGGTGAGGTTGTTCGCCTATTAAAGGGGATCGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGTTGCTATCTAACGGGGGTGTCAGGGCGGCTGAGGGGAAGGAGGCTCTAGTACGAGAGGAACGAGCCTCCGGCGCCACTGGTTTACCGGTTGTCGGCA-TCGCCGGGCAGCTACGCGCCACGCGGTTAAAGGCTGAAAGCATCTAAGCCTGAAACCGCCCCCGAA-AAGAGCCGCCAGGGC-TCCCGTAAAAGACGGGGTTGATAGGACCGGGGTGTAAGCCGTTCAGCCCGCGGTCACTAA
Bacillus_subtilis                                       GTTTGATCCTGGCTCAGGACGAACGCTGGCGGCGTGC--CTAATACATGCAAGTCGGCGGACGGGTGAGTAACACGTGGGTAACCTGCCTGTAAGACTGGGATAACTC--CGG-GAAACCGGGGCTAATACCGGATGATGGTTCAAACATAAAACACTTACAGATGGACCCGCGGCGCATTA-GCTAGTTGGTGAGGTAACGGCTCACCAAGGCAACGATGCGTAGCCGACCTGAGAGGGT-GATCGGCCACACTGGGACTGAGACACGGCCCAGACTCCTACGGGAGGCAGCAGTAGGGAATCTTCCGCAATGGACGAAAGTCTGACGGAGCAACGCCGCGTGGCTCTGTT-GTTAGGGAAGAAAGCCACGGCTAAC--TACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTTTCCGGAATTATTGGGCGTAAAGGGCTCGCAGGCGGTTTCTTAAGTCTGATGTGAAAGCCCCCGGCTCAACCGGGGAGGGTCA-TTGGAAACTGGGG-AACTTGAGTGCAGAAGAGGAGAGTGGAATTCCACGTTGTAGCGGTGAAATGCGTAGAGATGTGGAGGAACACCAGTGGCGAAGGCGACTCTCTGGTCTGTAACTGACGCTGAGGAGCGAAAGCGTGGGGAGCGAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGAGTGCTAAGTGGTGCTGCAGCTAACGCATTGAGCACTCCGCCTGGGGAGTACGGTCGCAAGACTGAAACTCAAAGGAATTGACGGGGGCCCGC-ACAAGCGGTGGA-GCATGTGGTTTAATTCGAAGCAACGCGAAGAACCT-TACTAGGTCTTGACATCCTCT-GACAATCGATAGGACGTCGACAGGTGGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGATCTTAGTTGCCAGTTGGGCACTCTAAGGTGACTGCCGGTGA-CAAACCG-GAGGAAGGTGGGGATGACGTCAAATCATCATGCCCCTTATGACTTGGGCTACACACGTGCTACAATGGACAGAACAAAGGGCAGCGAA-CCGCGAGGTTAAGCCAATCCCACAAATCTGTTCTCAGTTCGGATCGCAGTCTGCAACTCGACTGCGTGAAGCTGGAATCGCTAGTAATCGCGGATCAGC-ATGCCGCGGTGAATACGTTCCCGGGCCTTGTACACACCGCCCGTCACACCACGAGAGTTTGCGAAGGTGGGACAGATGATTGGGGTGAAGTCGTAACAAGGTAGCCGTATCGGAAGGTGCGGCTGGATCACCTGGATGCCTTGGCACTAGGAGCCGATGAAGGACGGGACGAACACCGATATGCTTCGGGGAGCTGT-AAGCAAGCTTTGATCCGGAGATTTCCGAATGGGACCCGGGGAACTGAAACATCTAAGTACCCGGA-GAAGAGAAAGCAAAT-GCGA-TTCCCTGAGTAGCGGCGA-CGAACACGGGATCAGCCCAAACAGATGAAG-AGGTCTGGAACATAGGAGGTAACAGCCCTGTAGTCAAACCTGAGTACGGCGGAACACGTGAAATTCCGTCGGAATCCGGGAGG-ACC-ATCTCCCAAGGCTAAATACTCCCTAGTGACCGATAGTGAACC-AGTACCGTGAGGGAAAGGTGAAAAGCACCCCGGA-AGGGGAGTGAAAGAGATCCTGAAACCGTGTGCCTATGATGGCGTGCCTTTTGTAGAATGAACCGGCGAGTTA-CGATCCCGTGCAA-GGTTAAGGAGCCGCAGCGAAAGCGAG-TCTGAATAAGTACGTGGTCGTA-GACCCGAAACCAGGTGATCTACCCATGTCCAGGGTGAAGTTCAG-GTAACACTGAATGGAGGCCCG---AACCCACGCACGTTGAAAAGTGCGGGGATGAGGTGTGGGTAGGGGTGAAATGCCAATCGAACCTGG-AGATAGCTGGTTCTCTCCGAAATAGCTTTAGGGCTAGCCTCAAG-GTAGTAGAGC-ACTGATTGGGCCCTCACCGGGTTACCGAATTCAGTCAAACTCCGAAGGGAGTCAGACTGCGA-GTGATAAGATCCGT-AGTCGAAAG-GGAAACAGCCCAGACCGCCAGCTAAGGTCCCAAAGTATACGTT-AAGTG-------GAAAAGGATGTGGAGTTGCTTAGACAACCAGGATGTTGGCTTAGAAGCAGCCA-CCATTTAAAGAGTGCGTAATAGCTCACTGGTC----GAGTGACTCTGCGCCGAAAATGTACCGGGGCT-AAACGTATCACCGAAGCTGCGGGTAGGAGA-GCGTTCTA-AGGGCTGTGAAGCCAG-ACCGGAAGGACTGGTGGAGAGAATGCCGGTATGAGTA-GCGAAA--AGAGGGGTGAGAATCCCTC-CACC-GAATGCCT-AAGGGTTCCTG-AGGAAGG-CTCGTCCGCTCAGGGTTAGTCGGGA-CCTAAGCCGAGGCGGCGATGGACAACAGGTTGATATTCCTGTACCCGCAGGAGGATAGGGGCAAATCCGTATAAGGCTGAGCTGT--GATATTCCACACTGCCAAGAAACGTACCGCAAACCGTCACAGGTAGGCGAGGA-GAGAA-TCCTAAGGTGA-TCGAGAGAACTCTC--GTTAAGGAACTCGGCAAAATGACCCCGTAACTTCGGGAGAAGGGGTGCTGAGAGCCGCAGTGAATAGGCCCAGGCGACTGTTTAGCAAAAACACAGGTCTCTGCGAAGCCG-TAAGGCGAAGTATAGGGGCTGACGCCTGCCCGGTGCTGGAAGGTTAAGAGGAGCGCTTAAAGCCCCAGTAAACGGCGGCCGTAACTATAACGGTCCTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCCGCACGAAAGGCGCAACGATCTGGGCGCTGTCTCAACGAGAGACTCGGTGAAATTAT--AGTACCTGTGAAGATGCAGGTTACCCGCGACAGGACGGAAAGACCCCGTGGAGCTTTACTGCAGCCTGATATTGGTACAGCTTGTACAGGATAGGTAGGAGCCTTGG---AGAGGCATCGGTGGGATACTACCCGACAGTGTCAGGTGGGCAGTTTGACTGGGGCGGT-CGCCTCCTAAAAGGTAACGGAGGCGCCCAAAGGTTCCCTCAGAATGGTTGGAAATCATTCGCAGAGTG-TAAAGGCACAAGGGAGCTTGACTGCGAGACCTA---CAAGTCGAGCAGGGACGAAAGTCGGGCTTAGTGATCCGGTGGTT---CCGCATGGAAGGGCCATCGCTCAACGGATAAAAGCTACCCCGGGGATAACAGGCTTATCTCCCCCAAGAGCTCCACATCGACGGGGAGGTTTGGCACCTCGATGTCGGCTCATCGCATCCTGGGGCTGTAGTCGGTCCCAAGGGTTGGGCTGTTCGCCCATTAAAGCGGTACGCGAGCTGGGTTCAGAACGTCGTGAGACAGTTCGGTCCCTATCCGTCGCGGGCGCT-GGAAATTTGAGAGGA-GCTGTCCTTAGTACGAGAGGACCGGGATGGACGCACCGCTGGTGTACCAGTTGTTGGCAT-CGCTGGGTAGCTATGTGCGGACGGGATAAGTGCTGAAAGCATCTAAGCATGAAGCCCCCCTCAAG-ATGAGATTTCAAGATCCCTGAAAGATGATCAGGTTGATAGGTCTGAGGTGGAACACATGGAGCTGACAGATACTAA
'Caldivirga maquilingensis IC-167'                      GGTTGATCCTG-CCGGACCCGACCGCTATCGGGGTGGGGCTTAGCCATGCGAGTCGGCGCACGGCTCAGTAACACGTGGCCAACCTACCCTCGGGAGGGGGATAACCC--CGG-GAAACTGGGGCTAATCCCCCATAAGGCCCCCTCCCCGAAACGCCCGAGGATGGGGCTACGGCCCATCATGGTAGCTGGCGGGGTAACGGCCCGCCAGGCCGAAGACGGGTGGGGGCCGTGAGAGCGG-GAGCCCCGAGATGGGCACTGAGACAAGGGCCCAGGCCCTATGGGGTGCAGCAGGCTCGAATACTCCGCAATGCGGTAACCCGCGACGGGGCCACCCCGAGTGCTTTTCCCCCGTGTAAGAATAAGCGGGGGGCAAG-TCTGGTGTCAGCCGCCGCGGTAATACCAGCTCCGCGAGTGGTCGGGGTGTTTACTGGGCCTAAAGCGCCCGTAGCCGGCCCGGTAAGTCACCCCTGAAATCCATGGGCTCAACCCATGGGCCGGG-GGTGATACTGCCG-GGCTTGGGGGTGGGAGAGGCCGAGGGTACTCCCGG-GGTAGGGGCGAAATCCGATAATCCCGGGAGGACCACCAGTGGCGGAAGCGCTCGGCTGGAACACGCCCGACGGTGAGGGGCGAAAGCTGGGGGAGCAAAGGGGATTAGATACCCCTGTAGTCCCAGCTGTAAACGATGCGGGCTAGCTGGTGGCGTAGGGAAGCCGTTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGGGCACCACAAGGGGTGAA-GCTTGCGGCTTAATTGGAGTCAACGCCGGAAACCT-CACCCGGGGCGACAGCAG-GATGAAGGCCGCTAACGACCTGAGAGGAGGTGCATGGCCGTCGCCAGCTCGTGCCGTGAGGTGTCCAGTTAAGTCTGGCAACGAGCGCGACCCCCGCTCCCTGTTGCTAGGGGGGCACACAGGGAGGACTGCCGGCG--TAAGCCG-GAGGAAGGAGGGGGCCACGGCAGGTCAGTATGCCCCGAAACCCCGGGGCTGCACGCGAGCTGCAATGGCGGGGACAGCGGGTTCCGACCCCGAAAGGGGGAGGCAATCCCGTAAACCCCGCCCCAGTAGGAATCGAGGGCTGTAACTCGCCCTCGTGAACGTGGAATCCCTAGTAACCGCGTGTCACC-AACGCGCGGTGAATACGTCCCTGCCCCTT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CTGG----------------GTCCCGTGCCC---------------------------------------------------------------------------------------------CT--------------AGAGCTGAAAAGAACCCCG-CGAGGGGTGTG-AAAAGAGCCTGAAACCGGACGGTTATCGCCGCTTACGTCCAGAAACACGAGCCAGGGAGTTCC-CATCTGTGGCGA-GTCTAAGGAGGCGTAGGGAAACCGAA-GGCCCGCAAGCCAC-AGGTGGGAGACCAGAAACCGAGCGATCTAGCCCGGGGTAGGGTGAAGCGGGG-CGAAAGCCCCGTGGAGGCCCG-ATTGGGGTTCTGACGTGCAAATCGTTCCCGTGACCCTGGGCTAGGGGCAAAAGACCAATCAAGCTCGG-TGATAGCTGGTTCCCCCCGAAGCAGCTCTTAGGCTGGCCTCCCTGGAGGTAGAG-CACTGATCCGGGGCCG-AAAGGCTCCGGTCCCGGGTCAAACTCCGAAGG-AGACGGGTTCCCCGGGGGTAAGCTTGGG-GGCCGAGAG-GGAAACAACCCAGACCGG-GGTTAAGGCCCCAAAGTGCGGGCT-AAGTGTC-AATCTAGAAGGGTGTCTCCCACCGAAGACGGCGGGACCGTAGGCCCAGCAGCAGCCA-TCGGCTAAGCAACGCGTAACAGCGGACCCGCT----GAGGTGGGAGGCCCCGAAGACGCACAGGGACTCAAGCCCGCCGCCGAGACCCCGGGTAGGGGG-GCGTCGCC-GTGGGGCGGAAGCC-GGGCCGTGAGGTCCGGTGGAGAGGATCCTGGCGGTAGTA-GCAGCG-AAGAGGGGTGGGATACCCCTCCGCCGGAAAGGCC-CAGGGTTCCAT-GGTAATG-TTCATCAGCCATGGGTTAGCCGGTC--CTAAGGTGGGGCG--AAAGGGAAACGGGTTAATAATCCCGTGCCCGTCTCAGGATAG-GGGAGTGCCGTATGGCGAGAACCGGTT-GAAACTCCTGGGGCCCATGAAACGTACCGAGAACCGACACAGGT-CGCCTGGGTGAGAA-GCCCAAGGCGGGTCGGGTC-ACGCCA-GGCTAGGGAACTCGGCAAATTAGCCCTGTAACTTCGGGATAAAGGGTGCCGTGGGTCGCAGTGGCAAGGGGGACCTGACTGTTTAACAAAAACATAGGTCCCCGCGAGCCCG-TAAGGGTTTGTACGGGGGCTGAATCCTGGCCACTGGCGGTACGTGAAACCCGGGTTCAAAAGCGCCGCTGAAGGCCGGGGGTAACTCTGACCCTCTTAAGGTAGCCAAATGCCTTGCCGGGTAAGTTCCGGCGTGCATGAATGGATCAACGAGGTCCCCACTGTCCCAGCCTGGTGCCCGGCGAACCCAC---CTCCAGGTGCAGAGTCCTGGGACCCCCGACGGGGCGAGAAGACCCTGTGGACCTTTACTGCAGCCCGTCGTTGGGAGGGGGTGCATAGTGTAGGTGGGAG-CGATG---AGATGCGTCAATGAAACACCACCCGACAGCGGCGGGTTGGCAGTTTGGCTGGGGCGGCACACCTCTGAAAAGATATCAGGGGTGCCCTAAGCTCCGCTCAGGTCGGTCAGAAACCGACCGTAGAGGG-TAAGGCCAAATGCGGGGCTGACTGCCCCCTTGAACGCTAGGGGGGCAGGGGGGAAACCCGGGCCTAGCGAACGCTCGTGC--CCCCACTGGAGGGGGCCGGGCATGTCGGA--AAAGGTACCCCAGGAGTAACCGGCTCGTCGCGGGTGAGAG-TTCCCATCGACCCCGCGGTTTGGTACCCAGACGTCGTCTCTTCCCATCCTGGCGGTGCAGCAGCCGCCAAGGGTGGGGCTGCCCGCCCATTAAAGGGGAACGTGAGATGGGTTCAGACCGTCGTGAGACAGGTCGGTCTCTACCTGTCGGGGGTGCT-GGCCGCCTGAGGGGAAGGTGCCCTCAGTACGAGAGGAACGGGGCGCCGCGGCCTCTAGTCTACCGGTTGTCGGCA-GTGCCGGGCAGCCACGCCGCTTGGGG-TAACCGCTGAAGGCATCTAAGCGGGAAACCCGCCCCTAA-AATAGGCGGCAGGGC-TCCCGTAGAAGACGGGGTTGATGGGGTGGTGGTGTAAGGGGG-GAGCCTGCCACTCCCAA
Candidatus_Korarchaeum                                  ---------------GAGGGAACCCCTATCGGGCTCGCACTAAGCCATGCGAGTCGGCGCACGGCTCCGTAATACACGGTCAACCTGTCCTGGGGACCGGGATAACCT--CGG-GAAACTGAGGTTAATACCGGATAATGGGTCCACCCCTAAAGGCCCCAGGGTGGGACCGTGGCCTATCA-GGTAGTAGGTGGGGTAACGGCCCACCTAGCCTAAGACGGGTACGGGCTCTGAGAGGAG-GAGCCCGGAGATGGGCACTGAGACAAGGGCCCAGGCCCTACGGGGCGCAGCAGGCGGGAAACTTCCCCAATGCGCGCAAGCGTGAGGGAGTGAGCCCGAGTGCTGTTCCCCTGTGTAAAAGGAAGGGGAGGGTAAG-GCTGGTGCCAGCCGCCGCGGTAAAACCAGCTCCCCGAGGGGTTCCCACGCATACTGGGCCTAAAGCGTCCGTAGCCGGCCCCGTAAGTCCTCGGTTAAATCCGCCTGA-AGACAGGCGGACCGCC-GAGGATACTGCGG-GGCTAGGGAGCGGGAGGGGCCGAGGGTATTCCGGG-GGGAGCGGTAAAATGCGTAGATCCCCGGAGGACCACCAGTGGCGAAGGCGCTCGGCTGGAACGCGTCCGACGGTGAGGGACGAAAGCTGGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCCAGCCGTAAACGATGCCGGCTAGGTGGTGTCGAAGCGAAGGCATTAAGCCGGCCGCCTGAGGAGTACAGCCGCAAGGCCGAAACTTAAAGGAATTGACGGGGGGGCACCACAAGGGGTGAATGCCTGCGGCTCAATTGGACTCAACGCCGGGAATCT-TACCGGGGGCGACAGCAG-GATGAAGGTCGCTGAAGACCTGAGGGGTGGTGCATGGCCGTCGCCAGCTCGTGCCGTGAGGTGTCCTGTTAAGTCAGGCAACGAGCGAGACCCCCGCCCTCAGTTGCCAGCCGGGCAAACTGGGGGGACTGCCGGCGA-AGAGCCG-GAGGAAGGAGGGGGCTACGGCAGGTCAGTATGCCCCTAATCCCCCGGGCCGCACGCGGGCTGCAATGGGCGGGACAGCGGGATGCGACCCCGAGAGGGGGAGCAAATCCCTGAAACCCGCCCGTGGTTGGGATCGAGGGTTGCAACTCGCCCTCGTGAACCCGGAATCCCTAGTAACCGCGGTTCTCC-ATACCGCGGTGAATACGTCCCTGCCCCTTGTACACACCGCCCGTCAACCCACCCGAGTGGACGAGCTTTGGGTCCGCGAGGGGGGGTAAGT------------------------------------------GGATGGCTCGGCTC-GGGCGCCGAGGAAGGGGGTGGCAAGCTGCCATAAGCCCCGGGGAGCCGC-AGGCAGGCTTCGATCCGGGGATCCCCGAATGGCACCCCCCGAATTGAAGCATCTCAGTAGGGGGAGGAGGAGAAACCAACC-GGGA-TGCCCTGAGTACCGGCGAGGGAAAGGGGCT-GAGCTCAAACAGCCGAAG-TGGCCTGGAACATAGAGGGTGAGAGCCCCGTAGGCGTACCCGAGTACCGTGGGTTG---GAATACCCGCGGGAATCCGGGGGTCATC-GACCTCCAAAGCTAAATACGTCCCGA-GACCGATAGCGAACTGAGTACCGTGAGGGAAAGCTGAAAAGCACCGCT-GGCGCGGGGTG-AAAAGAGCCTGAAACCAGGCGGTCATCGCCCCGTACGTCTTGAAACACGCGCCGGGGAGTTCA-CGGGCGTGGCGA-GCCTAAGAAGGCGGAGCGAAAGCGAGGACCCCGCAAGTCAC-GCTCGTGAGACCAGAAGCCGGGCGATCTACTCCTGGGCAGGGCGAAGCCGGGTCGCGAGCCCGGTGGAGGCCCG-ATAGGGATGGTGAGGTGCAAATCCCTCCCGTGACCTGGGAGTAGGGGCAAAAGACCAATCTAGCCCGG-CAATAGCTGGTTCCCGCCGAAGCCTCCCGCAGGAGGATCTCCGCGGAGGTAGGG-CAACGATTGGGGGCTC----CGCCCCGCCACCCTCTCGAACCCCGAAGG-AGCCGGG--CGGCGGGGGGAAGCTCCGT-CGCCGAGAG-GGGAACAACCCGGACCGG-GGTTAAGGTCCCCAAGTCCTGGCT-AAGTGCCGAAATCCGAAGGGCGTCTCCCTCCTAAGACAGCGGGGAGGTAGGCTCAGAAGCAGCCA-TCCTTTAAAGAGTGCGTAAAAGCTCACCCGCC----GAGGAGGGAGGCCCCCAAAATGAGTCGGGGCTGAAGCCAGGCACCGATACCCCGGGTAGGCGG-GCGCGCAC-ACCGGGCGGAAGCC-GGGGCGTGAGCTCCGGTGGAGCAAATCCCGGCGGTAGTA-GCAGCG-AAGTGGGGTGAGAATCCCCACGGCC-GAAAGCGC-CAGGGTTCGCC-GGCAATGCTTCGTCAGCCGGCGGTTAGCCGGTC--CTAAGGCGGCACG--AAAGGGAAGCCGGTTAATATTCCGGCGCCCGCCTCGGGCTAG-GCGAGAACCGTATGGTGAGAAGCGGCT-GAAATGCCTGGGGACCTTGAAACGTACCGAGATCCGACACAGGTGCGC-TGGCTGAGAAGGCCTAAGGCCTATCGGTCCTAACGCG-GGAGAGGGAACTCGGCAAATTGGCCCCGTAACTTCGGGAGATGGGGTGCCGCAGGTCGCAGTGACAAGGGGCGCCCGACTGTTTAACAAAAACATAGTTCCCCGCGAGCCCG-CAAGGGTGTGTACGGGGGATGAGGCCTGGCCAATGCCGGTACCTGAAGCCCCGGTACAAAAGGGCCGGTGAAAGCCGGGAGTAACTCTGACTCTCTTAAGGTAGCCATATGCCTTGCCGAATAAAAATCGGCGTGCATGAATGGCTTAACGAGGTGCCCGCTGTCCCCTCCCGCGGGCCGGTGAACCCGC---ATCCCGGTGTACAGACCGGGACGCCCCAACGGGGAGAGAAGACCCTGTGGAGCTTCACTGCAGCCTGGTCTTGGCTGGGGATGCAGAGGGTAGGCGGGAGCGAT-----GGAAGCGACGATGGAACACCGCCCGACAGGGCCAGGTGGGCAGTTTGGCTGGGGTGGCACGCCCCTGCAAAGGTATCAGGGGCGCCCTAAGGCGAGCTCAGGCGGGACAGAAACCCGCCGTAGAGGG-CAAGGCCAAAAGCTCGCCTGACTGGATCCCTAAACGCGTGGGATCCAGGGGTGAAAGCCGGGCCTAGCGAACACTCGAG---CCCTCTCGGTGAGGGCCGGGTACGACAAA--AAAGTTACCCCAGGGGTAACGGAGCTGTGGCGGGCGAGAG-TCCCCATCGGCCCCGCCGCTTGCTTCCCCGACGTCGGCACTGCCCATCCTGGGGGTGCAGCAGCCTCCAAGGGTGGGGATGTTCGCCCATTAAAGGGGAACGTGAGCTGGGTTCAGAACGTCGCGAGCCAGTTCGGTTTCTCCCTGTTGGGGCTGCAAGGCCGCCTGAGGGGAAGGGACCCTTAGTACGAAAGGAACGGGGTGTCGGGGCCTCCGGTGTACCGGTCGTCGGCG-ACGCCGGGTAGCCGCGCCCCAGCCGA-TAAGGGCTGAAAGCATCTAAGCCCGAAGCGGCCCCCGAA-AATAGGCGGC---GCCCCTCG----------------TGGGGTTAGGGCGCG------------------------
Cenarchaeum_symbiosum                                   GGTTGATCCTG-CCGGACCTGACTGCTATCGGATTGATACTAAGCCATGCGAGTCGGCAGACGGCTCAGTAACACGTAGTCAATCTAACCTATGGACGGGGATAACCT--CGG-GAAACTGAGAATAATATCCGATAATGGTTTGTGGCCCAAACGCCGTAGGATGGGACTGCGGTCTATCA-GCTTGTTGGTGAGGTAATGGCCCACCAAGGCTATAACAGATACGGGCTCTGAGAGGAG-AGGCCCGGAGATGGGTACTGAGACACGGACCCAGGCCCTATGGGGCGCAGCAGGCGAGAAAACTTTGCAATGTGCGAAAGCACGACAAGGTTAATCCGAGTGCTTTTACCGGTCTTAAAAATAAGGGGTGGGCAAGTTCTGGTGTCAGCCGCCGCGGTAAAACCAGCACCTCAAGTGGTCAGGAGGATTATTGGGCCTAAAGCATCCGTAGCCTGCCGTGTAAGTTTTCGGTTAAATCTATGCGCTCAACGCATAGGCTGCC-GGAAATACTGCAC-GGCTAGGGAGTGGGAGAGGTAGACGGTACTCGGTA-GGAAGGGGTAAAATCCTCTGATCTATCGATGACCCCCTGTGGCGAAGGCGGTCTACTAGAACACGTCCGACGGTGAGGGATGAAAGCTGGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCCAGCTGTAAACAATGCAAACTCAGTGGTGCCGCAGGGAAGCCGTTAAGTTTGCCGCCTGGGAAGTACGTACGCAAGTATGATACTTAAAGGAATTGGCGGGGGAGCACCACAAGGGGTGAA-GCCTGCGGTTCAATTGGAGTCAACGCCAGAAATCT-TACCCGGAGAGACAGCAG-TGTGAAGGTCGCTGAAGACTCGAGAGGTGGTGCATGGCCGTCGCCAGCTCGTGCCGTGAGATGTCCTGTTAAGTCAGGTAACGAGCGAGATCCTTGCCTCTAGTTGCCAGTGGGGCGAATTAGCGGGACCGCCGCAGT-TAATGCG-GAGGAAGGAAAGGGCCACGGCAGGTCAGTATGCCCCGAAACTCTGGGGCCACACGCGGGCTGCAATGGTAGTGACAATGGGTTCCATATCCGAAAGGAGGAGGTAATCCCC-AAACGCTACCACAGTTATGACTGAGGGCTGCAACTCGCCCTCACGAATCTGGAATCCCTAGTAACCGCGCGTCATT-ACCGCGCAGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCGTTTCATTGAAGTTTGCGAACTTGAGGTAAGCGACAAGGGAAAAGTCGTAACAAGGTGACCGTAGGGGAACCTGCGGTCGGATCACCTGGATTGCTAGGCTT-GAGGAGAGAAGAAGGACGTGGCAAGCTGCGATAAGCTCGGGGTAGGTGC-ACGCACCCGTTGATCCCGAGATTTCCGAATAGGACCGTGGGAATTGAAGCATCTTAGTACCACGAGGAAGAGAAATCAATA-GAGA-TTTCCCAAGTAGAGGCGATCGAAAAGGAAA-GAGCCCAAACAGTTGAAG-TGTTCTGAAACTTAGAGGGTGATACCCCCCTAGACGAACCCGAGTAGTTGTCCTTG---GCAGTGGGCAGCGAAGATTGGTGAAAGT-AGCATCAAAGGCTAAATATCTCTCAA-GACCGATAGTGTACT-AGTACCGTGAGGGAAAGCTGAAAAGTACCCCG-GAAGGGGGGTG-AAAAGTGCATGAAACCTATTGCTTATCATGCGTTCCGTCTCGAAACACGGGCCAGGGAGCTTG-CTGTCATGGCGA-GGTTAAGTAGCCGAAGGGAAACCGAA-TTCTCGCAAGTCAT-GGCGGTAAGGCTAGAAGCCAGTCGATCTATTCCTGAGCAAGATGAAGGTGGG-CGAAAGCCCACTGGAGGTCTG--CAGCAGTTCTGACGTGCAACTCGTTTGTGTGACTTGGGAATAGGGGTCAAAAACCAATCTAGACTGG-CGCTTGCTAGTTCCAACCGAAGCGTCTCGCAGGGCGTGCTATGTGGAGGTAGAG-CACTGATAGGGGGAAG-AGATTCCTCACCATCCATTCAAACTCCGAAGG-ACACGGGTTCGTGTGACGTAAGGTTCAC-GACCGAGAG-GGGTTTAACCCAGACTGG-AGTTAAGGTCCCCAAATTTCTGCT-AAGTGTC--AAGCCAAAGTGCGTGTCATCGCCAAGACAGCAGGGAGGTAAGCTCAGAAGTAGCTA-TCCTTCAAAAAGTGTGTAACAACTTACCTGCC----GAGCGAGGGCGCCACAAAAACGGAC-GGGGCTAAAGCAGAGTACCGATACTCCAGGTAGGTTG-GCGTAGTG-ATTGGGACGAAGCA-GGGCGGTGACGTCCTGTGGAGCAGATCCTGGTGGCAGTA-ACAGCA-TAGTGCGGTGAGAATCCGCACCACC-GTAAGCGC-AAGGGTTTCCA-GGCAATGCGTCGTCAGCCTGGAGTTAGTCGATC--CTAAGGACTGCCG--AATGGGAAACCAGTTAATATTCTGGTACCCGCTTCCGGATAG-GGGAGTGTCGTATGACGAGAACAGGCC-CGAATTCCAGGAGACCATGAAACGTACCCAGATCCGACACAGGTGCGC-TGGTTTAGTA-AACTAAGGTGCTACGGGTATACCGTATGGCGAGGGAATTCGGCAAATTAGTCCTGTAGCTTAGGTATAAGGGATGCCGCAGGTTGCAGTGACAAGGGGGTTTCGACTGTTTAATAAAAACACAGGCGACTGCTAGCCCG-AAAGGGTATGTATAGTCGCTGAATCCTGGCCGGTGCCGGTATCTAAAACTTGGGTTCAAAAGGACCGGTTAACGCCGGGAGTAACTCTGACTCTCTTAAGGTAGCCAAATGCCTTGTCGGGTAAGTTCCGACGTGCATGAATGGAACAACGAGAGCCCCACTGTCCCCGCCTACAACCCGGTGAAGCCACATAAGGTGGACGAACAGTCCATCATCTTCCATCGGGGAGAGAAGACCCCGTGGAGTTTTACTGCAGCTTGTGCTTGGCAGGGAGTGCATAGCGTATCTGGGAGTCATTTCCTGGGGACGCCGATGTAACACCAGACGACATGTGCAGGTGGGCAGTTCGGCTGGGGCGGCACCCCTTTGAAAAGATATCAAAGGGGCCCAAAGTTTAGTTCAAGCGGGTCAGAAATCCGCTGAAGAGGG-CAAAGCCAAAAACTAGACTGAATGGATTTCCAAACGCACGGAATTCATAGACGAAAGTCTGGCTTAGCGATCCTTCGTGT--GCCCACTATTGGGGCCCGGAGGTGACAGA--AAAATTACCCCAGGGATAACAGGCTCGTCGCGGGCGAGAG-CTCCTATCGACCCCGCGGTTTGGTACCTCGATGTCGGCTTTTCCTATCCTGGTCCTGCAGCAGGGGCCAAGGGTGAGGCTGCTCGCCTATTAAAAGGGAACATGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGCCTCTGCCTGATGGAAGCGC--GAATATCTGAGGGGAAGTCGCTCTTAGTACGAGAGGAACAGAGAGGCGTGGCCACTGGTCTACCGGTTGTCGGCA--GGCCGGGCAGCTAAGCCATCTAGGC-TAAGTGCTGAAAGCATCTAAGCACGAATCCTATCCCGAG-ACAAGATATTAAGGTTCGCAGAAGAAGACTGCGTTGATAGGAAGGTGGTGTAAG-TGGTGAGCCAGCCTTTACTAA
Cytophaga_hutchinsonii                                  ---------------------------GGCGAC----------------------GGCGCACGGGTGCGTAACACGTATGCAACCTACCTTAAACTGGGAGATAGCCC--GGG-GAAACTCGGATTAATACCCCATAATGACATGATTGTTAAACGGTTTAAGATGGGCATGCGTTCGATTA-GCTAGTTGGTGAGGTAATGGCTCACCAAGGCTACGATCGATAGGGGGTCTGAGAGGAT-GATCCCCCACACTGGTACTGAGATACGGACCAGACTCCTACGGGAGGCAGCAGTAGGGAATATTGGTCAATGGAGGCAACTCTGAACCAGCCATGCCGCGTGCTACTTTTGATTGGGAAAATAAGCCACGGCTAAC--TACGTGCCAGCAGCCGCGGTAATACGTAGGTGGCAAGCGTTGTCCGGATTTATTGGGTTTAAAGGGTGCGTAGGCGGCTTAATAAGTCAGTGGTGAAAGCCGATCGCTTAACGATCGAACTGCC-ATTGATACTGCTA-GGCTTGAGTATAGATGAGGTAGGCGGAATTGACAG-TGTAGCGGTGAAATGCATAGATATTGTCAAGAACACCAATTGCGAAGGCAGCTTACTAAGTTATAACTGACGCTGAGGCACGAAAGTGCGGGGATCAAACAGGATTAGATACCCTGGTAGTCCGCACCGTAAACGATGATCACTCGCTGGCGGCCAAGCGAAAGCGATAAGTGATCCACCTGGGGAGTACGCCCGCAAGGGTGAAACTCAAAGGAATTGACGGGGGTCCGC-ACAAGCGGTGGA-GCATGTGGTTTAATTCGATGATACGCGAGGAACCT-TACCTAGGCTAGA-ATGTGAA-GGAATGTAATGGTGCAGTACAAGGTGCTGCATGGCTGTCGTCAGCTCGTGCCGTGAGGTGTTGGGTTAAGTCCCGCAACGAGCGCAACCCCTATCTTTAGTTGCCAGTCGGGGACTCTAGAGAGACTGCCTGTG--TAAACAGAGAGGAAGGAGGGGACGACGTCAAGTCATCATGGCCCTTACGCCTAGGGCTACACACGTGCTACAATGGCGCATACAGAGTGTTGCAAGCTAGTGATAGCAAGCCAATCACAAAAAGTGCGTCTCAGTTCGGATTGAAGTCTGCAACTCGACTTCATGAAGCTGGAATCGCTAGTAATCGCGTATCAGCAATGACGCGGTGAATACGTTCCCGGACCTTGTACACACCGCCCGTCAAGCCATGAAAGTCTGTCAGGGTAAAACAGGTAATTAGGGCTAA-----------------------------------------------------------------------------------------------------------------------------------------------------GAACTGAAACATCTAAGTAACTGGAGGAAGAGAAAATAACTAATGA-TTCCCTAAGTAGTGGCGAGCGAACAGGGAA-GAGCCCAAACAACTGGAA-ATGTCTGGGACATAGCGGGTGAGAGCCCCTTACAGGTACCTGAGTAGGGCGGGACCGGAGAAATCCCGTTTGAAACTGCCGGC-ACC-ATCCGGTAAGGCTAAATACTCCTGAGAGACCGATAGTGAACC-AGTACCGTGAGGGAAAGGTGAAAAGTACCCTGAATAAGGGGGTGAAATAGAACCTGAAACCATACGCTTATGACGGCGTGCCTTTTGCATAATGATCCTACGAGTTACTCCTCACTGGCAA-GGTTAAGTAGCCGGAGCGAAAGCGAG-TCTGAATAAGTCAGTGGGGGTA-GACGCGAAACCTTGTGATCTACCCATGGCCAGGATGAAGTTGCA-GTAACATGCAATGGAGGTCCG---AACTGGTAAACGTTGAAAAGTTTTCGGATGAGCTGTGGGTAGGGGTGAAAGGCTAATCAAACTGGG-AAATAGCTCGTACTCCCCGAAATGTATTTTGGTACAGCGTCGGGGTAAGTAGAGCTACCAATAGGGGAGTCAA-ATCCTACCAAATCCTGATGAACTCCGAAGGCAGTGAGGGCTTGG-GTGCTAAGGTCCAA-GTCCGAGAG-GGAAAGAACCCAGACTAACAGCTAAGGTCCCAAAATCTATCCT-AAGTT-----GAACAAAGGAGGTCCAGTTGCAGAGACAGCCAGGATGTTTGCTCGGAAGCAGCAATTCATTTAAAGAGTGCGTAACAGCTCACTGGTC----GAGCGACAGGGCATCGATAATA-AACGGGCATCAAGGGTAGTACCGAAGCTTTAGGTAGGGGA-GCATTCCA-AGGCCGGTGAAGGCGA-AACGCGAGTTTTGCTGGAGCAAATGTAGGAATAAGTA-ACGATA--ATAAGGGTGAGAATCCCTTACACC-GATAGACT-AAGGTTTCCTG-ATCAACG-TTCGTCGGATCAGGGTTAGTCGGGA-CCTAAGGCAAATCGTCGATGGACAACTGGTTAATATTCCAGTACTCGGAGTAGTGAAAAGGCAAATCCGC------TCGAGATGTC-GAATAAACAGACTTCCAAGAAACGTACCGCAAACCGACACAGGTAGTCAAGGA-GAGAA-TCCTGAGGTGC-GCGAGTGATTCACG--GCTAAGGAACTCGGCAAATTAACCCTGTAACTTCGGGAGAAGGGGTGCTAGAAGCCGCAGTGAAAAGTCTCAGGCGACTGTTTAACAAAAACACATGGCTCTGCGAAATCG-AAAGATAAAGTATAGGGCCTGACACCTGCCCGGTGCCGGAAGGTTAAGAGGGGGGCTTAAAGCCCCGGTAAACGGCGGCCGTAACTATAACGGTCCTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCTGCACGAATGGTGTAACGATCTGAGAACTGTCTCAGCCGTGAGCTCGGTGAAATTGT--AGTAGCGGTGAAGATGCCGCTTACCCGTCACGGGACGGAAAGACCCCGTGCACCTTTACTATAGCTTTGCATTGGTAAATGATGTGTAGGATAGGTGGGAGGCTTTG---AGAGCCAACGTTGAAATACCACCCAACAGTGCATGGTGGGTAGTTTGACTGGGGTGGT-CGCCTCCAAAAAAGTATCGGAGGCTTCTAAAGGTTCCCTCAGTACGCTTGGTAACCGTACGTAGAGTG-CAATGGCATAAGGGAGCTTGACTGTGAGACAAA---CAAGTCGATCAGGTACGAAAGTAGAGCATAGTGATCCGGTGGTT---CCGCATGGAAGGGCCATCGCTCAAAGGATAAAAGGTACGCCGGGGATAACAGGCTGATCTCCCCCAAGAG-CTCACATCGACGGGGAGGTTTGGCACCTCGATGTCGGCTCGTCACATCCTGGGGCTGGAGAAGGTCCCAAGGGTTCGGCTGTTCGCCGATTAAAGTGGCACGCGAGCTGGGTTCAGAACGTCGTGAGACAGTTCGGTCCCTATCTGTGATGGGCGTA-GGAAGTTTGAGTGGA-CCTGACCTTAGTACGAGAGGACCGGGT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Desulfurococcus_kamchatkensis                           GGTTGATCCTG-CCGGTCCCGACCGCTATCGGGGTGGGGCTAAGCCATGGGAGTCGGCGGACGGCTGAGTAACACGTGGCTAACCTACCCTCGGGAGGGGGATAACAC--CGG-GAAACTGGTGCTAATCCCCCATAAGGGTCCCTCCTCGAAACGCCCGAGGATGGGGCTACGGCCCATTA-GGTAGTTGGCGGGGTAACGGCCCGCCAAGCCGATAATGGGTAGGGGCCGTGAGAGCGG-GAGCCCCCAGATGGGCACTGAGACAAGGGCCCAGGCCCTACGGGGCGCACCAGGCGCGAAACCTCCGCAATGCGGGAAACCGTGACGGGGCCACCCCGAGTGCTTTTCCCCGCTGTAGGAATAAGCGGGGGGCAAG-TCTGGTGTCAGCCGCCGCGGTAATACCAGCCCCGCGAGTGGTCGGGACGATTATTGGGCCTAAAGCGCCCGTAGCCGGCTCGACAAGTCTCCTCCTAAATCCTCGGGCTCAACCCGAGGATTGGA-GGAGATACTGTCG-AGCTAGGGGGTGGGAGAGGCCGAGGGTACTCCCGG-GGTAGGGGCGAAATCCTATAATCCCGGGAGGACCACCAGTGGCGAAGGCGCTCGGCTGGAACACGCCCGACGGTGAGGGGCGAAAGCCGGGGGAGCGAACCGGATTAGATACCCGGGTAGTCCCGGCTGTAAACGATGCGGGCTAGGTGGTGCCGCAGGGAAGCCGTTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTCAAAGGAATTGGCGGGGGAGCACCACAAGGGGTGGA-GCCTGCGGTTCAATTGGAGTCAACGCCGGGAATCT-CACCGGGGGAGACAGCAG-GATGACGGCCGTTAAAGGCCTGAGAGGAGGTGCATGGCCGTCGCCAGCTCGTGCTGTGAAGTGTCCGGTTAAGTCCGGAAACGAGTGAGACCCCCACCCCTAGTTGCGACCGGGGCACACTAGGGGGACTGCCGCCGTTTAAGGCG-GAGGAAGGAGGGGGCCACGGCAGGTCAGCATGCCCCGAATCCCCCGGGCTACACGCGGGCTACAATGGCGGGGACAATGGGATCCGACCCCGAAAGGGGGAGGCAATCCCTCAAACCCCGCCGTAGTTGGGATCGAGGGCTGCAACTCGCCCTCGTGAACGAGGAATCCCTAGTAACCGCGTGTCAAC-ATCGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCGCTCCACCCGAGGGGACGAACTCCCCCTCCCTGAGGGGGGAGAAGTCGTAACAAGGTAGCCGTACCGGAAGGTGCGGCTGGATCACCTGGATGGCTCGGCTC-GGGCGCCGAGGAAGGCCGTGGCAAGCTGCGATAAGCCCGGGGTAGGCGC-AGGCAGCCGTTGAACCCGGGATCGCCGAATGGGACCCCCCGAACGGAAACATCTTAGTAGGGGGAGGAAAAGAAACCAAAC-GGGA-TCCCCTGAGTAGGGGCGACCGAAAGGGGGA-GAGCCCAGACAGCCGAAG-TGACCTGGAACGTAGAGGGTGATAGCCCCGTAGGCTAA-CAGAGTACCACGGCTTG---GTTTTGCCGTGGGAAGTCGGGGGTCACC-GACCTCCAAGGCTAAATACGTCCCGA-GACCGATAGCGAACTAAGTACCGTGAGGGAAAGCTGAAAAGCACCCCG-CAAGGGGGGTG-AAAAGAGCCTGAAACCGGGCGGCTATCGTGCCGTCCGTCTTGAAACACGGGCCGGGGAGTCCA-CGGCAGTGGCGA-GCCTAAGTAGGCGTAGGGAAACCGACAAGCCCGCAAGTCAC-TGCCGTGGGACCAGAAACCGGGCGATCTAGGCGGGGGCAGGGTGAAGCCGGG-GGAAACCCCGGTGGAGGCCCG--AAAGGGTTCTGACGTGCAATTCGTTCCCATGACCCCCGTCTAGGGGCAAAAGACCAATCTAGCCCGG-TGATAGCTGGTTCCCGCCGAAGTGGGTCTCAGCCCAGCCCCGCCGGAGGTAGAGCTACGGATCGGAGGCCG-AAAGGCCTCGGTCCCCGGTCCAACTCCGAAGG-AGTGGGGTTCCCC-GGCGTAAGGCTGGG-GGCCGCGAG-GGGAACAACCCAGACCGG-GGTTAAGGCCCCAAAGTGCCGGCT-AAGTGCC-AATGCAAAAGGGCGTCCTACGGCTTAGACAGCGGGGAGGTGGGCCTAACAGCAGCCA-TCCTTTAAAGAGTGCGTAACAGCTCACCCGCA----GAGCCGTAGGGCCCCGAAGATTAGTCGGGGCTCAAGCCGGCCGCCGAGACCCCGGGTAGGCGG-GCGCCGGG-TCGGGGCAGAAGTC-GGGCCGTGAGGTCCGATGGAGAAGATCCCGGCGGCAGTA-ACAGCG-AAGAGGGGTGGGAATCCCCTCCGCCGGAAAGGGC-AAGGGTTCCTC-GGCAACG-GTCGTCGGCCGAGGGTTAGCCGGTC--CTAACCCGGGCCG--AATGGGAAACGGGTTAATATTCCCGTGCCCGCCTCTGGATAG-GGGAGTACCGTATGGTGAGAAGGGGCC-GAAATTCCAGGGGCCCTTGAAACGTACCGAGAACCGACACAGGTGCCCCTGGGTTAGAA-GCCCAAGGCGTGTGGGGGCTAACCCA-GGCCAGGGAACTCGGCAAATTGGCCCCGTAACTTCGGGAGAAGGGGTGCCGCAGGCCGCAGTGCCTAGGGGGGCCTGACTGTTTAATAAAAACATAGGTCCCCGCAAGCCCG-AAAGGGTTTGTACGGGGGCTGAATCCTGGCCACTGGCGGTCCGTGAAACCGGGGTCCAAAAGCGCCGCTGAAGGCCGGGAGTAACTCTGACTCTCTTAAGGTAGCCAAATGCCTTGCCGGGTAAGTTCCGGCGCGCATGAATGGATCAACGAGGTCCCCACTGTCCTGGCCTGGGGCCCCGTGAATACAC--GGAGCCGGTGCATAGGCCGGCAACCCCCCGCAGGGCGATAAGTCCCCGTGGAGCTTTACCGCAGCCTGGCGCTGGGTTGCGGTGCGTAGCGTAGGTGGGAGCCTGTG---AGAGGCGTCAATGAAACACCACCCGACAACGCCAGGTGGGCGGTTCGGCTGGGGCGGCACGCCCGCGAAAAGATAACACGGGCGCCCAAAGGTCGGCTCAGGCGGGTTAGAGCTCCGCCGTAGAGTG-CAAGGGCAAAAGCCGGCCTGACCGGACCCTTGAACACAAGGGGTCCGGCCGGGAAACCGTGGCCTAGCGAACGCTCGTGC--CCCCCTCGGTGGGGGCCGGGCATGACAGA--AAAGTTACCCCGGGGATAACAGAGTCGTCGCGGGCGAGAG-CTCCCATCGACCCCGCGGTTTGCTACATCGATGTCGGCTCTTCCCATCCTGGGGGTGCAGCAGCCTCCAAGGGTGGGGCTGCCCGCCCATTAAAGGGGAACGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGACTCTACCCGCGGGGGGTGCG-GGCCGCCTGAGGGGAAGCTACCCTCAGTACGAGAGGAACGGGGTGGCGCGGCCTCTGGTTTACCGGTTGTCGGCA-ACGCCGGGCAGCCACGCCGCAAGGGG-TAACCGCTGAAAGCATCTAAGCGGGAACCCCTCCCCGAA-AAGAGGCGGCCGGGC-TCCCGTAGAAGACGGGGTTGATGGGGCGGGGGTGTAAGGGGTTCAGCCCGCCGCTCCCAA
Escherichia_coli                                        GTTTGATCATGGCTCAGATTGAACGCTGGCGGCAGGC--CTAACACATGCAAGTCGGCGGACGGGTGAGTAATGTCTGGG-AAACTGCCTGATGGAGGGGGATAACTA--CTG-GAAACGGTAGCTAATACCGCATAACGTCGCAAGACCAAAGTGCCATCGGATGTGCCCAGATGGGATTA-GCTAGTAGGTGGGGTAAAGGCTCACCTAGGCGACGATCCCTAGCTGGTCTGAGAGGAT-GACCAGCCACACTGGAACTGAGACACGGTCCAGACTCCTACGGGAGGCAGCAGTGGGGAATATTGCACAATGGGCGCAAGCCTGATGCAGCCATGCCGCGTGGTACTTTC-AGCGGGGAAAGAAGCACCGGCTAAC--TCCGTGCCAGCAGCCGCGGTAATACGGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCACGCAGGCGGTTTGTTAAGTCAGATGTGAAATCCCCGGGCTCAACCTGGGAACTGCA-TCTGATACTGGCA-AGCTTGAGTCTCGTAGAGGGGGGTAGAATTCCAGG-TGTAGCGGTGAAATGCGTAGAGATCTGGAGGAATACCGGTGGCGAAGGCGGCCCCCTGGACGAAGACTGACGCTCAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGTCGACTTG---CTTCCGGAGCTAACGCGTTAAGTCGACCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGC-ACAAGCGGTGGA-GCATGTGGTTTAATTCGATGCAACGCGAAGAACCT-TACCTGGTCTTGACATCCACG-GAAGTTTGATGAGAATGTGACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTTGTGAAATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTATCCTTTGTTGCCAGCCGGGAACTCAAAGGAGACTGCCAGTGA-TAAACTG-GAGGAAGGTGGGGATGACGTCAAGTCATCATGGCCCTTACGACCAGGGCTACACACGTGCTACAATGGCGCATACAAAGAGAAGCGACCTCGCGAGAGCAAGCGGACCTCATAAAGTGCGTCGTAGTCCGGATTGGAGTCTGCAACTCGACTCCATGAAGTCGGAATCGCTAGTAATCGTGGATCAGA-ATGCCACGGTGAATACGTTCCCGGGCCTTGTACACACCGCCCGTCACACCATGGGAGTGGGCCACTTTGTGATTCATGACTGGGGTGAAGTCGTAACAAGGTAACCGTAGGGGAACCTGCGGTTGGATCACCTGGATGCCCTGGCAGTCAGAGGCGATGAAGGACGTGCTAATCTGCGATAAGCGTCGGTAAGGTGATATGAACCGTTATAACCGGCGATTTCCGAATGGGACCGGGGGAACTGAAACATCTAAGTACCCCGAGGAAAAGAAATCAACC-GAGA-TTCCCCCAGTAGCGGCGAGCGAACGGGGAG-GAGCCCAGA-TAGTGGAA-GCGTCTGGAAGATACAGGGTGACAGCCCCGTACACAAA--TGAGTAGGGCGGGACACGTGGTATCCTGTCTGAATATGGGGGG-ACC-ATCCTCCAAGGCTAAATACTCCTGACTGACCGATAGTGAACC-AGTACCGTGAGGGAAAGGCGAAAAGAACCCCGGCGAGGGGAGTGAAAAAGAACCTGAAACCGTGTACGTATGACTGCGTACCTTTTGTATAATGGGTCAGCGACTTA-TATTCTGTAGCAA-GGTTAAGGAGCCGAAGGGAAACCGAG-TCTTAACTAGTTGCAGGGTATA-GACCCGAAACCCGGTGATCTAGCCATGGGCAGGTTGAAGGTTGG-GTAACACTAACTGGAGGACCG---AACCGACTAATGTTGAAAAATTAGCGGATGACTTGTGGCTGGGGGTGAAAGGCCAATCAAACCGGG-AGATAGCTGGTTCTCCCCGAAAGCTATTTAGGTAGCGCCTCGTG-AATGTAGAGC-ACTGTTTCGGGTCATCCCGACTTACCAACCCGATGCAAACTGCGAAGGGAGACACACGGCGG-GTGCTAACGTCCGT-CGTGAAGAG-GGAAACAACCCAGACCGCCAGCTAAGGTCCCAAAGTCATGGTT-AAGTG-------GGAAACGATGTGGGAAGGCCCAGACAGCCAGGATGTTGGCTTAGAAGCAGCCA-TCATTTAAAGAAAGCGTAATAGCTCACTGGTC----GAGTCGGCCTGCGCGGAAGATGTAACGGGGCT-AAACCATGCACCGAAGCTGCGGGTAGGGGA-GCGTTCTGTAAGCCTGTGAAGGTGG-CCTGTGAGGGTTGCTGGAGCGAATGCTGACATAAGTA-ACGATA--AAGCGGGTGAAAAGCCCGCTCGCC-GGAAGACC-AAGGGTTCCTG-TCCAACG-TTAATCGGGGCAGGGTGAGTCGACC-CCTAAGGCGAGGCGTCGATGGGAAACAGGTTAATATTCCTGTACTCGGAGAAGGCTAT-GGCAAATCCGG-CAAGGCTGAGGCGT--GATATGCCCTGCTTCCAGGAAACGTACCCCAAACCGACACAGGTGGTCAGGTA-GAGAA-TACCAAGGCGC-TTGAGAGAACTCGG--GTGAAGGAACTAGGCAAAATGGTGCCGTAACTTCGGGAGAAGGCACGCTATCAGTCGAAGATACCAGCTGGCTGCAACTGTTTATTAAAAACACAGCACTGTGCAAACACG-AAAGTGGACGTATACGGTGTGACGCCTGCCCGGTGCCGGAAGGTTAATTGATGGGGTTAAAGCCCCGGTAAACGGCGGCCGTAACTATAACGGTCCTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCTGCACGAATGGCGTAATGATGGCCAGGCTGTCTCCACCCGAGACTCAGTGAAATTGA--ACTCGCTGTGAAGATGCAGTGTACCCGCGGCAAGACGGAAAGACCCCGTGAACCTTTACTATAGCTTGACACTGAGCCTTGATGTGTAGGATAGGTGGGAGGCTTTG---AGAGCCGACCTTGAAATACCACCCGACAGTGTCTGGTGGGTAGTTTGACTGGGGCGGT-CTCCTCCTAAAGAGTAACGGAGGAGCACGAAGGTTGGCTAATCCTGGTCGGACATCAGGAGGTTAGTG-CAATGGCATAAGCCAGCTTGACTGCGAGCGTGA---CGGCGCGAGCAGGTGCGAAAGCAGGTCATAGTGATCCGGTGGTT---CTGAATGGAAGGGCCATCGCTCAACGGATAAAAGGTACTCCGGGGATAACAGGCTGATACCGCCCAAGAG-TTCATATCGACGGCGGTGTTTGGCACCTCGATGTCGGCTCATCACATCCTGGGGCTGAAGTAGGTCCCAAGGGTATGGCTGTTCGCCATTTAAAGTGGTACGCGAGCTGGGTTTAGAACGTCGTGAGACAGTTCGGTCCCTATCTGCCGTGGGCGCT-GGAGAACTGAGGGGG-GCTGCTCCTAGTACGAGAGGACCGGAGTGGACGCATCACTGGTGTTCGGGTTGTCGGCAC-TGCCCGGTAGCTAAATGCGGAAGAGATAAGTGCTGAAAGCATCTAAGCACGAAACTTGCCCCGAG-ATGAGTTCTCAAGGAACGTTGAAGACGACGACGTTGATAGGCCGGGTGTGTAATGCGTTGAGCTAACCGGTACTAA
Haloarcula_marismortui_ATCC_43049                       GGTTGATCCTG-CCGGAGGCCATTGCTATCGGAGTCCGATTTAGCCATGCTAGTTAGCATATAGCTCAGTAACACGTGGCCAAACTACCCTACAGACCGCGATAACCT--CGG-GAAACTGAGGCCAATAGCGGATAGTGTCGAGAGTGAGAAACGCTGTAGGATGTGGCTGCGGCCGATTA-GGTAGATGGTGGGGTAACGGCCCACCATGCCGATAATCGGTACAGGTTGTGAGAGCAA-GAGCCTGGAGACGGTATCTGAGACAAGATACCGGGCCCTACGGGGCGCAGCAGGCGCGAAACCTTTACACTGCACGACAGTGCGATAGGGGGACTCCGAGTGCTTTTCTGAACCGTAAGAACAAGGACTGGGCAAG-ACCGGTGCCAGCCGCCGCGGTAATACCGGCAGTCCAAGTGATGGCCGATATTATTGGGCCTAAAGCGTCCGTAGCTTGCTGTGTAAGTCCATTGGGAAATCGACCAGCTCAACTGGTCGGCGTCCGGTGGAAACTACAC-AGCTTGGGGCCGAGAGACTCAACGGGTACGTCCGG-GGTAGGAGTGAAATCCTGTAATCCTGGACGGACCACCAATGGGGAAACCACGTTGAGAGACCGGACCCGACAGTGAGGGACGAAAGCCAGGGTCTCGAACCGGATTAGATACCCGGGTAGTCCTGGCTGTAAACAATGCTCGCTAGGTAGTGCCGTAGTGAAGACGATAAGCGAGCCGCCTGGGAAGTACGTCCGCAAGGATGAAACTTAAAGGAATTGGCGGGGGAGCACCACAACCGGAGGA-GCCTGCGGTTTAATTGGACTCAACGCCGGACATCT-CACCGGTCCCGACAGTAGTAATGACAGTCGTTGACGACTTGAGAGGAGGTGCATGGCCGCCGTCAGCTCGTACCGTGAGGCGTCCTGTTAAGTCAGGCAACGAGCGAGACCCACACTTCTAGTTGCCAGTTGGGTACACTAGGAGGACTGCCATTGC-TAAAATG-GAGGAAGGAATGGGCAACGGTAGGTCAGTATGCCCCGAATGGACCGGGCAACACGCGGGCTACAATGGCTATGACAGTGGGATGCAACGCCGAAAGGCGAAGCTAATCTCC-AAACGTAGTCGTAGTTCGGATTGCGGGCTGAAACCCGCCCGCATGAAGCTGGATTCGGTAGTAATCGCGTGTCAGA-AGCGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCAAAGCACCCGAGTGGGCGAATCTGGGCTCCGCAAGGGGGCTTAAGTCGTAACAAGGTAGCCGTAGAGGAATCTGCGGCTGGATCACCTGGATTGCTCGGCTC-AGGCGCTGATGAAGGACGTGCCAAGCTGCGATAAGCCATGGGGAGCCGC-ACGGAGGCGAAGAACCATGGATTTCCGAATGAGACCCCGAGAACTGAAACATCTCAGTATCGGGAGGAACAGAAAACGCAATGTGA-TGTCGTCAGTAACCGCGAGTGAACGCGATA-CAGCCCAAACCGACGAAG-TCTCTTGGAAGATACAGGGTGACAACCCCGTACTCGAGCCAGAGTAGCGGGGGTTG---GATATCCCTCGCGAATAACGCAGGCATC-GACTGCGAAGGCTAAACACAACCTGA-GACCGATAGTGAACA-AGTAGTGTGAACGAACGCTGCAAAGTACCCTCAGAAGGGAGGCGAAATAGAGCATGAAATCAGTTGGCGATTCTGTCGTACGTTTTGAAAAACGAGCCAGGGAGTGTG-TCTGTATGGCAA-GTCTAAGGAGGCACAGGGAAACCGACATGGCCGCAAGCCAT-GTGGACACGACCCGAATCCGGACGATCTACGCATGGACAAGATGAAGCGTGC-CGAAAGGCACGTGGAAGTCTG-TTAGAGTTGGTGTCCTACAATACCCTCTCGTGATCTATGTGTAGGGGTGAAAGGCCCATCGAGTCCGG-CAACAGCTGGTTCCAATCGAAACATGTCGAAGCATGACCTCCGCCGAGGTAGAGCGACCGATTGGCCTCCGAGAGGAGTCGGCACACCTGTCAAACTCCAAAGG-ATTCCGGTGCGC--GGGGTAAGCCTGTG-TACCAGGAG-GGGAACAACCCAGAGATA-GGTTAAGGTCCCCAAGTGTGGATT-AAGTGTAATCCTCTGAAGGTGGTCTCGAGCCCTAGACAGCCGGGAGGTGAGCTTAGAAGCAGCTA-CCCTCTAAGAAAAGCGTAACAGCTTACCGGCC----GAGGTTTGAGGCGCCCAAAATGATC-GGGACTCAAATCCACCACCGAGACCTGTCGTAGATTG-GCGCTCTA-ATTGGATGGAAGCA-GGGGCGAGAGCTCCTGTGGAGAAAATCCTGGCCATAGTA-GCAGCGATAGTCGGGTGAGAACCCCGACGGCC-TAATGGAT-AAGGGTTCCTC-AGCACTG-CTGATCAGCTGAGGGTTAGCCGGTC--CTAAGTCTCACCGA-AATGGGAAACAGGTTAATATTCCTGTGCCCGCCCTGGGGTCG-AGGA-AGCCGTATGGCAGGAAGCGGAC-GAA--ACCTGGGGCCCATGAAACGTACCGAGAACCGACACAGGTGTCCATGGCGGCGAA-AGCCAAGGCCTGTCGGGAGCAACCAA-CGTTAGGGAATTCGGCAAGTTAGTCCCGTACCTTCGGAAGAAGGGATGCCGCAGGTCGCAGTGACTCGGAAGCTCGGACTGTCTAGTAACAACATAGGTGACCGCAAATCCG-CAAGGACTCGTACGGTCACTGAATCCTGCCCAGTGCAGGTATCTGAACACCTCGTACAAAAGGACCTGTCAACGGCGGGGGTAACTATGACCCTCTTAAGGTAGCGTAGTACCTTGCCGCATCAGTAGCGGCTTGCATGAATGGATTAACCAGAGCTTCACTGTCCCAACGTTGGGCCCGGTGAACTGTA--CATTCCAGTGCGGAGTCTGGAGACACCCAGGGGGAAGCGAAGACCCTATGGAGCTTTACTGCAGGCTGTCGCTGGTCGCCGATGTGCAGCATAGGTAGGAGTCGTTACAGACAGACAACAGTGAAATACTACCCGACACCGATAGCCGGGCAGTTTGACTGGGGCGGTACGCGCTCGAAAAGATATCGAGCGCGCCCTATGGTCATCTCAGCCGGGACAGAGACCCGGCGAAGAGTG-CAAGAGCAAAAGATGACTTGACAGTGTTCTTCCCAACGAGGAACGCTGACGCGAAAGCGTGGTCTAGCGAACCAATTAG---CCTGCTTGATGCGGGCAATTGATGACAGA--AAAGCTACCCTAGGGATAACAGAGTCGTCACTCGCAAGAG-CACATATCGACCGAGTGGCTTGCTACCTCGATGTCGGTTCCCTCCATCCTGCCCGTGCAGAAGCGGGCAAGGGTGAGGTTGTTCGCCTATTAAAGGAGGTCGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGCTGCTATCTACTGGGTGTGTAATGGTGTCTGACAAGAACGACCGTATAGTACGAGAGGAACTACGGTTGGTGGCCACTGGTGTACCGGTTGTTAGCACGTGCCGGGTAGCCACGCCACACGGGG-TAAGAGCTGAACGCATCTAAGCTCGAAACCCACTTGGAA-AAGAGACA-CAGGTC-CCGCGTACAAGACGCGGTCGATAGACTCGGGGTGTGAGACGTTAAGCCCACGAGCACTAA
Halobacterium_salinarium_R1                             GGTTGATCCTG-CCGGAGGCCATTGCTATCGGAGTCCGATTTAGCCATGCTAGTTAGCGGAAAGCTCAGTAACACGTGGCCAAGCTACCCTGTGGACGGGAATACTCT--CGG-GAAACTGAGGCTAATCCCCGATAAGGGGCAAAGCCGGAAACGCCACAGGATGCGGCTGCGGTCGATTA-GGTAGACGGTGGGGTAACGGCCCACCGTGCCCATAATCGGTACGGGTTGTGAGAGCAA-GAGCCCGGAGACGGAATCTGAGACAAGATTCCGGGCCCTACGGGGCGCAGCAGGCGCGAAACCTTTACACTGTACGAAAGTGCGATAAGGGGACTCCGAGTGCTTTTGTACACCGTAAGAATAAGGACTGGGCAAG-ACCGGTGCCAGCCGCCGCGGTAATACCGGCAGTCCGAGTGATGGCCGATCTTATTGGGCCTAAAGCGTCCGTAGCTGGCTGAACAAGTCCGTTGGGAAATCTGTCCGCTTAACGGGCAGGCGTCCAGCGGAAACTGTTC-AGCTTGGGACCGGAAGACCTGAGGGGTACGTCTGG-GGTAGGAGTGAAATCCTGTAATCCTGGACGGACCGCCGGTGGCGAAAGCGCCTCAGGAGAACGGATCCGACAGTGAGGGACGAAAGCTAGGGTCTCGAACCGGATTAGATACCCGGGTAGTCCTAGCTGTAAACGATGTCCGCTAGGTGGTGCCGTAGGGAAGCCGAGAAGCGGACCGCCTGGGAAGTACGTCTGCAAGGATGAAACTTAAAGGAATTGGCGGGGGAGCACTACAACCGGAGGA-GCCTGCGGTTTAATTGGACTCAACGCCGGACATCT-CACCAGCCCCGACAGTAGTAATGACGGTCGTTGATGACCTGAGAGGAGGTGCATGGCCGCCGTCAGCTCGTACCGTGAGGCGTCCTGTTAAGTCAGGCAACGAGCGAGACCCGCACTCCTAATTGCCAGCTGGGTACATTAGGTGGACTGCCGCTGC-CAAAGCG-GAGGAAGGAACGGGCAACGGTAGGTCAGTATGCCCCGAATGGGCTGGGCAACACGCGGGCTACAATGGTCGAGACAATGGGAAGCCACTCCGAGAGGAGGCGCTAATCTCCTAAACTCGATCGTAGTTCGGATTGAGGGCTGAAACTCGCCCTCATGAAGCTGGATTCGGTAGTAATCGCGTGTCAGC-AGCGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCAAATCACCCGAGTGGGCAAATCTGGGCTCCGCAAGGGGGATTAAGTCGTAACAAGGTAGCCGTAGGGGAATCTGCGGCTGGATCACCTGGATAGCTCGGCTC-GGATGCCGACGAAGGACGTGCCAAGCTGCGATAAGCCTGAGGGAGCCGC-ACGGAGGCTAAGAACTCAGGATCTCCTAATGGGACGGCCGGAATTGAAGCATCTCAGTACGGCCAGGAAGAGAAATCGAAT-GAGA-CGCCGTTAGTAATGGCGAATGAACGCGGCA-CAGTCCAAACGTGTGAAG-TCTCCTGAAAGATACAGGGTGACAGCCCCGTATCACGGCCAGAGTAGCGGGGGTTG---GAAATCCCTCGTGAATGTGGCAGGCATC-GACTGCCAAGACTAAGTACTCTCCGA-GACCGATAGTGAACA-AGTAGTGTGAACGAACGCTGAAAAGCACCCCACAAAGGGGGGTGAAATAGGGCTTGAAATCAGGTGGCGATTCCGTCGTACGTTTTGAAAAACGAGCCAGGGAGTGTG-CCTGTTTGACGA-GTCTAAGAAGGCGTAGGGAAACCAATATGGCCGCAAGTCAA-ACGGGCACGACCCGAAACCCGGTGATCTACGCGTGGGCAAGGTGAAGCATGG-CGAAAGCCATGTGGAGGCCTG-TTAGGGTTGGTGTCTTTCAACACCCTCCCGTGACCTACGTGTAGGGGTGAAAGGCCCATCGAACCGGG-CAACAGCTGGTTCCAACCGAAACATGTCGAAGCATGACCTCTGCCGAGGTAGAGCGACCGATTGGACTCCGAGAGGAGTTGTCTCCCCTGTCAAACTCCAAAGG-AATCCGGTGTGC--GGGGTAAGCCTGTG-CACCGTGAG-GGAGACAACCCAGAGTTA-GGTTAAGGTCCCAAAGTGCGAGCT-AAGTGCG----ATTGAAGGTGGTCTCGAGCCCTAGACAGCCGGGAGGTGAGCTTAGAAGCAGCTA-CCCTCTAAGAAAAGCGTAACAGCTTACCGGCC----GAGGTTCGAGGCGCCCAAAATGATC-GGGGCTCAAGTTCGCCACCGAGACCTAACGTAGGTTG-GCATTCTG-TTCGGGTGGAAGCT-CGGGTGAGAACTCGAGTGGAGAAAATCCTGGCCATAGTA-GCAGCGTTAGTCGGGTAAGAATCCCGATGGCC-GAAAGAGC-AAGGGTTCCTC-GGCAATG-CTTATCAGCCGAGGGTTAGCCGATC--CTAAGGCCCGTCA--AAAGGGAAACTGGTTAATATTCCAGTGCCCGCCTCGGAGCAG-CGGA-AGCCGTATGGCAGGAAGCGAAC-GAAAT--CTGGGGCCCGTGAAACGTACCGAGATCCGACACAGGTGCTC-TGGCAGAGGA-AGCCAAGGCCTGTCGGGAATAACCGA-CGTTAGGGAATTCGGCAAGTTAGTCCCGTAAGTTCGCGATAAGGGATGCCGCAGGTCGCAGTGACTCGGAGGCTCCGACTGTCTAATAACAACATAGGTGACCGCAAATCCG-CAAGGACGCGTACGGTCACTGAATCCTGCCCAGTGCGGGTATCTGAACACCCAGTACAAAAGGACCCGTTAACGGCGGGGGTAACTATGACCCTCTTAAGGTAGCGTAGTACCTTGCCGCTTCAGTAGCGGCTTGCATGAATGGATCAACGAGAGCCTCACTGTCCCAACGTTGGGCCCGGTGAACTGTA--CGTTCCAGTGCGGAGTCTGGAGACCCCCAAGGGGAAGCGAAGACCCTATAGAGCTTTACTGCAGGCTGTCGCTGGTCGCTGATGTGCAGAGTAGGTAGGAGACGTTACACAGAGTCACACATGAAACACTACCCGACACCGGTAGCCGGGCAGTTTGACTGGGGCGGTACGCGCTTGAAAAGATATCGAGCGCGCCCTAAGCCTATCTCAGCCGAGTCAGAGACTCGGCGAAGAGTG-CAAGAGCATAAGATAGGCTGACAGTGTCCTACACAACGAGGGACGCTGACGCGAAAGCGTGGTCTAGCGAACCAATTAG---GCTGCTTGATGCGGCCAATTGCTGACAGA--AAAGCTACCTTAGGGATAACAGAGTCGTCACTCGCAAGAG-CACATATCGACCGAGTGGCTTGCTACCTCGATGTCGGTTCCCTCCATCCTGCCCGTGCAGAAGCGGGCAAGGGTGAGGTTGTTCGCCTATTAAAGGAGGTCGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGCTGCTATCTATTGGGGGTGTTTTGGTGCTTGACAGGAACGTTCGTATAGTACGAGAGGAACTACGAACGGGTGCCACTGGTGTATCGGTTGTCGGCATGTGCCGAGCAGCTACGCACCACGGGG-TAAGAGCTGAATGCATCTAAGCTCGAAACCCACCTGGAA-AAGAAGCA-CAGACC-GCTCGTAGAAGACGAGTTCGATAGACTTGGGGTGTAAGACGTTTAGCCCGCGAGTACTAA
Halorubrum_lacusprofundi_ATCC_49239                     GGTTGATCCTG-CCGGAGGCCATTGCTATTGGGATTCGATTTAGCCATGCTAGTCGGCGAATAGCTCAGTAACACGTGGCCAAACTACCCTTCGGAGCACGATACCCT--CGG-GAAACTGAGGTTAATAGTGCATAATGAGGATTGTGCCAAACGCCGAAGGATGTGGCTGCGGCCGATTA-GGTAGACGGTGGGGTAACGGCCCACCGTGCCAATAATCGGTACGGGTCATGAGAGTGA-GAACCTGGAGACGGAATCTGAGACAAGATTCCGGGCCCTACGGGGCGCAGCAGGCGCGAAACCTTTACACTGCACGCCAGTGCGATAAGGGAATCCCAAGTGCTTTTGTACACCGTAGGAATAAGGGCTGGGCAAG-ACCGGTGCCAGCCGCCGCGGTAATACCGGCAGCCCGAGTGATGGCCGATCTTATTGGGCCTAAAGCGTCCGTAGCTGGCCGCGCAAGTCTATCGGAAAATCCACCCGCTCAACGGGTGGGCGTCCGGTAGAAACTGCGT-GGCTTGGGACCGGAAGGCGCGACGGGTACGTCCGG-GGTAGGAGTGAAATCCTGTAATCCTGGACGGACCACCGATGGCGAAAGCACGTCGCGAGGACGGATCCGACAGTGAGGGACGAAAGCCAGGGTCTCGAACCGGATTAGATACCCGGGTAGTCCTGGCCGTAAACAATGTCTGTTAGGTGGTGCCGTAGGGAAGCCGCTAAACAGACCGCCTGGGAAGTACGTCCGCAAGGATGAAACTTAAAGGAATTGGCGGGGGAGCACTACAACCGGAGGA-GCCTGCGGTTTAATTGGACTCAACGCCGGACATCT-CACCAGCGTCGACTGTAATAATGACGATCGTTGATGACCTGAGAGGAGGTGCATGGCCGCCGTCAGCTCGTACCGTGAGGCGTCCTGTTAAGTCAGGCAACGAGCGAGACCCGCATCCTTACTTGCCAGCTGGGGACAGTAGGGAGACCGCCGTGGC-CAACACG-GAGGAAGGAACGGGCAACGGTAGGTCAGTATGCCCCGAATGCGCTGGGCAACACGCGGGCTACAATGGTCGAGACAAAGGGTTCCAACTCCGAAAGGAGACGGTAATCTCAGAAACTCGATCGTAGTTCGGATTGTGGGCTGCAACTCGCCCACATGAAGCTGGATTCGGTAGTAATCGCGTGTCATA-AGCGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCAAAGCACCCGAGTGAGCGAATCTGGGCTTCGCAAGGGGGCTTAAGTCGTAACAAGGTAGCCGTAGGGGAATCTGCGGCTGGATCACCTGAATGGCTCGGCTC-GAGAGCCGATGAAGGACGTGCCAAGCTGCGAAAAGCTCATGGGACCCGC-ATGGAGGGGAAGAACATGAGATATCCGAATCGGACTCCCTGAATTGAAACATCTCAGTAAGGGAAGGAAAAGAACGCAATA-GCGA-TGTCGTCAGTAACCGCGAGTGAACGCGACA-CAGCCCAAACATCTGAAG-TCTCCTGGAAGAGACAGGGTGACAACCCCGTAAGATGACCAGAGTAGCAGGGGTCG---GATATCCTCTGTGAACGACTCAGGCATC-CCCTGAGAAGGCTAAACACTCCTCGA-GACCGATAGCGAACA-AGTAGCGTGAGCGAACGCTGAAAAGCACCCCGAGAAGGGCGGTGCAATAGGGCCTGAAATCAGTTGGCGATCGTGTCGTGCGTTTTGAAAAACGACCCAGGGAGTGCA-CTTGATTGGCGA-GTCTAAGAAGGCGTAGGGAAACCGATACGGCCGCAAGTCAA-TTGGGTGCGACCCGAAACCAGGCGATCTATACACAGGCAGGGTGAAGCGTGG-CGAAAGCCACGTGGAGGCCCG-TTAGAGTTGGTATTCTACAATATCCTCTCGTGATCTGTGCATAGGGGTGAAAGGCCCATCGAGCCTGG-CAACAGCTGGTTCCAACCGAAACATGTCGAAGCATGACCTCTTCCGAGGTAGAGCTACCGATTGGCCTCCGAGAGGAGTCGGCCATCCTGTCGAACTCCAAAGG-AGTCCGGTGCGC--GGGGTAAGCCTGTG-TACCGTGAG-GGGAACAACCCAGAGCCG-GGTTAAGGTCCCAAAGTGTAGATT-AAGTGCG---ATTCGAAGGTGGTCTCAAGCCCTAAACAGCCGGGAGGTGAGCTTAGAAGCAGCTA-CCCTCTAAGAAAAGCGTAACAGCTTACCGGCC----GAGGTTTGAGGCGCCCAAAATGATC-GGGGCTCAAATCTACCACCGAGACCT--GGTAGGTTG-GCGTTCTG-TTCGGATGGAAGCA-CGGGTGAGAACTCGTGTGGAGACAATCCTGGTCACAGTA-GCAGCGATAGTCGGGTGAGAACCTCGACGGCC-TGAAGAGC-AAGGGTTCCTC-GGCACTG-CCACTCAGCCGAGGGTCAGCCGGTC--CTAAGATGCACC---AACGGGAAACTGGTTAAGATTCCAGTGCCCGCCGTGTGGAAC-GGGA-AGCCGTACGGCACGAAGCGAGCGAAA-TACATAGGGCCCGTGAAACGTACCAAGATCCGACACAGGTGCTC-TGGCAGCGCA-AGCCAAGGCCTGTCGGGAG-AACCGA-CGTTAGGGAATTCGGCAAGTTAGTCCCGTACCTTCGGAAGAAGGGATGCCGCAGGTCGCAGTGACTCGGGCGCTCCGACTGTCTAATAACAACACAGGTGACCGCAAATCCG-CAAGGACTCGTACGGTCACTGAATCCTGCCCAGTGCGGGTATCTGAACACCTCGTACAAAAGGACCCGTCAACGGCGGGGGTAACTATGACCCTCTTAAGGTAGCGTAGTACCTTGCCGCTTCAGTAGCGGCTTGCATGAATGGATAAACGAGAGCGCCACTGTCCCAACGTTGGACCCGGTGAACTGTA--CGTTCCAGTGCGGAGTCTGGAGACCCCCAAGGGGAAGCGAAGACCCTATAGAGCTTTACTGCAGGCTGTCGCTGGTCGCCGATGTGCAGCATAGGTAGGAGTCATTACACAGAGACAACATTGAAATACTACCCTACACCGGTAGCCGGGCAGTTTGACTGGGGCGGTACGCGCTCGAAAAGATATCGAGCGCGCCCGAAGATCATCTCAGCCGGGTCGGGAATCCGGCGAAGAGCG-CAAGAGCACAAGATGGTCTGACAGTGTCATTCCCAACGAGTGACGCTGACGCGAAAGCGTGGTCTAGCGAACCTACGAG---GCTCCGGAATGGGGCCCGTAGATGACAGA--AAAGCTACCTTAGGGATAACAGAGTCGTCACCCGCAAGAG-CACATATCGACCGGGTGGCTTGCTACCTCGATGTCGGTTCCCTCCATCCTGCCCGTGCAGAAGCGGGCAAGGGTGAGGTTGTTCGCCTATTAAAGGAGGTCGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGCTGCTATCTATTGGGGGTGTCAAGGTACTTGACGTGAACAAACGTATAGTACGAGAGGAACTACGTTTGGTCGCCACTGGTGTACCGGTTGTGCGCA-ATGCCGGGTAGCCACGCGACACGGGG-TAAGAGCTGAACGCATCTAAGCTCGAAACCCACATGGAA-AAGAAGTAC-AGGTC-ACTCGTAGAAGACGAGTTCGATAGACTCGGGATGTAAGGTGTTGAGTCCACGAGCACTAA
'Ignicoccus hospitalis KIN4/I'                          -------------CGGACCCGACCGCTATCGGGGTAAGGCTAAGCCATGGGAGTCGGCGGACGGCTGAGTAACACGTGGCTAACCTACCCTCGGGAGGGGGATAACAC--CGG-GAAACTGGTGCTAATCCCCCATAAGGGTTCCGCCCCGAAACGCCCGAGGATGGGGCCGCGCCCCATCA-GGTAGTTGGCGGGGTAATGGCCCGCCAAGCCGAAGACGGGTAGGGGCCGTGGGAGCGG-GAGCCCCCAGATGGGCACTGAGACAAGGGCCCAGGCCCTACGGGGCGCACCAGGCGCGAAAACTCCGCAATGCGGGCAACCGTGACGGGGTTACCCCGAGTGCTTTTCCCCGCTGTAAAAATAAGCGGGGGGCAAG-TCTGGTGTCAGCCGCCGCGGTAATACCAGCCCCGCGAGTGGTCGGGACGATTATTGGGCCTAAAGCGCCCGTAGCCGGCCTGGTGGCCCCCCTCCTAAAGCCCCGGGCTCAACCCGGGGACTGGA-GGGGGTAGCGCCA-GGCTAGGGGGCGGGAGAGGCCGAGGGTACTCCCGG-GGTAGGGGCGAAATCCGATAATCCCGGGAGGACCGCCAGTGGCGAAGGCGCTCGGCTGGAACGCGCCCGACGGTGAGGGGCGAAAGCCGGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCCGGCTGTAAACGATGCGGGCTAGGTGGTGCCGCAGGGAAGCCGTTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAAGGGGTGGA-GCCTGCGGCTTAATTGGAGTCAACGCCGGGAACCT-TACCGGGGGCGACAGCAG-GATGAAGGTCGCTGAAGACCTGAGAGGAGGTGCATGGCCGTCGCCAGCTCGTGCCGTGAGGTGTCCGGTTAAGTCCGGCAACGAGCGAGACCCCCGTCCCCAGTTGCTACCGGGGCACACTGGGGAGACTGCCGCCGTATAAGGCG-GAGGAAGGAGGGGGCTATGGCAGGTCAGCATGCCCCGAAACCCCCGGGCTGCACGCGGGCTACAATGGCGGGGACAGCGGGTTGCGACCCCGAAAGGGGGAGCCAATCCCTGAAACCCCGCCGAGGTTGGGATCGAGGGCTGCAACTCGCCCTCGTGAACGCGGAATCCCTAGTAACCGCGCGTTAGC-ATCGCGCGGTGAACACGTCCCTGCTCCTTGCACACACCGCCCGTCGCTCCACCCGAG-----------------------GGGGGAGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGGCTCGGCTC-GGGCGCCGACGAAGGGCGTGGCAAGCTGCGATAAGCCCGGGGGAGGCGC-ACGCAGCCGTCGAACCCGGGATCCCCGAATGGGACCCCCCGAACGGAAACATCTTAGTAGGGGGAGGAAGAGAAACCACCACGGGA-TCCCCCGAGTAGGGGCGACCGAAAGGGGGG-TAGCCCAAACACCCGAAC-TCCGGTGGAACGTAGAGGGTGACAGCCCCGTAGGGGAA--TGAGTACCACGGCTTG---GTATTGCCGTGGGAAGCTGGGTGGCACC-AGCATCCAAGGCTAAACACGTCCCGA-GACCGATAGCGAACTAGGTACCGTGAGGGAAAGCTGAAAAGCACCCCT-GGCGGGGGGTG-AAAAGAGCCTGAAACCGGGCGGTCATCGCACCTTTCGTCTTGAAACACGGGCCGGGGAGTGCA-CGGCCGTGGCGA-GGCTAAGTAACCGCAGGGAAACCGACGAGCCCGCAAGTCAC-GGTCGTGCGACCCGAAACCGGGCGATCTAGGCGGGGGCAGGGTGAAGCCGGG-CGAAAGCCCGGTGGAGGCCCG--CAAGGGTTCTGACGTGCAATTCGTTCCCCTGACCTCCGCCTAGGGGTGAAAGGCCAATCTAGCTCGG-TGATAGCTGGTTCCCGCCGAAGTGGGTCTAAGCCCAGCGTCCCCGGAGGTAGAGCTACTGATGGGGGGGCGTAGGCCCCCCGGCCTCCCGTCAAACTCCGAAGC-AGTGGGGCGCCCC-GGGGTAAGCCCGGG-GGCCGAGAG-GGGAACAACCCAGACCGG-GGTTAAGGCCCCCAAGTGCCGGCT-AAGTGCC--AACCGAAAGGGCGTCTCGGGCCTCAGACAGCGGGGAGGTGGGCCTAACAGCAGCCA-CCCTCTAAGGAGTGCGTAACAGCTCACCCGCC----GAGGCCCGAGGCCCCGAAGATTGGTCGGGGCTTAAGCCGGCCGCCGAGACCCCGGGTAGGCGG-GCGTCGGG-GCGGCCCAGAAGGC-GGGCCGTGAGGTCCGCTGGAGCCGATCCCGGCGGTAGTA-ACAGCG-AAGAGGGGTGAGAATCCCCTCCGCCGGAAAGGGC-AAGGGTTCCCC-GGCAACT-GTCATAGGCCGGGGGTGAGTCGGTC--CTAACCCGCCTCG--AAAGGGAAGCCGGTTAATATTCCGGCACCCGCCTCGGGGTAG-GGGAGGGCCGTACGGCGAGAAGGGGCC-GAAATCCCTGGGGCCCATGAAACGTACCGAGAACCGACGCAGGTGCCCCTGGGTGAGAA-GCCCAAGGCGGCTGGGGGTTAACCCG-GGCCAGGGAACTCGGCAAATTGGCCCCGTAACTTCGGGAGAAGGGGTGCCGCAGGTTGCAGTGCCTAGGGGGGCCTGACTGTTTAATAAAAACATAGGTCCCCGCAAGCCCG-AAAGGGTGTGTACGGGGGCCGAATCCTGGCCACTGGCGGTCCGTGAAACCGGGGTTCAAAAGCGCCGCTGAAGGCCGGGAGTAACTCTGACTCTCTTAAGGTAGCCAAATGCCTTGCCGGGTAAGTTCCGGCGCGCATGAATGGATCAACGAGGTCCCCACTGTCCCGGCCCGGGGCCCCGTGAACCCCC--TGAGCCGGTGCACAGTCCGGCAACCCCCCGTAGGGAGAGAAGACCCCGTGGAGCTTTACTGCAGCCCGGCGTTGGGTGGGGGTGCGTAGCGTAGGTGGGAGCCGGTG---AGAGGCGCCCATGAAACACCACCCGACAGCGCCGGGTGGGCAGTTTGGCTGGGGCGGCACGCCCGCGAGAGGGTAACACGGGCGCCCTAAGGTCGGCTCAGGCGGGTCAGAAACCCGCCGTAGAGTG-CAAGGGCAAAAGCCGGCCTGACCGGACCCCTAAAGGCAGGGGGTCCGGCCGGGAAACCGCGGCCTAGCGAACGCTCGTGT--CCCCCCTGGTGGGGGCCGGGCATGACAGA--AAAGTTACCCCGGGGATAACAGAGTCGTCGCGGGCGAGAG-CCCACATCGACCCCGCGGTTTGCTACCTCGATGTCGGCTTTTCCCATCCTGGGGGTGCAGCAGCCCCCAAGGGTGGGGCTGCCCGCCCATTAAAGGGGAACGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGACTCTACCCACGGGGGGTGTC-GGCCGCCTGAGGGGAAGGTGCCCTCAGTACGAGAGGAACGGGGCGCCCCGGCCTCTGGTGTACCGGTTGTCGGCA-GAGCCGGGCAGCTACGCCGGAAGGGG-TAACCGCTGAAAGCATCTAAGCGGGAACCCCACCCCGAA-AAGAGGCGGCAGGGC-TCCCG-------------------------------------------------------
Metallosphaera_sedula_DSM_5348                          GGTTGATCCTG-CCGGACCCGATCGCTATAGGGGTAGGGCTAAGCCATGGGAGTCGGCGGACGGCTGAGTAACACGTGGCTAACCTGCCCTTGGGATCTGGATAACCC--CGG-GAAACTGGGGCTAATCCGGAGCGATGATCTCTTGCCTAAACGCCCAAGGATGGGGCTGCGGCCCATCA-GGCTGTTGGGGGAGTAAAGGTCCCCCAAACCGATAACGGGTAGGGGCCGTGGGAGCGG-GAGCCCCCAGTTGGGCACTGAGACAAGGGCCCAGGCCCTACGGGGCGCACCAGGCGCGGAACGTCCCCAATGCGGGAAACCGTGAGGGCGTTACCCCTAGTGCTTTTCTCCACTCCAGAAATAAGCGGGGGGCAAG-ACTGGTGTCAGCCGCCGCGGTAATACCAGCCCCGCGAGTGATCGGGACGTTTATTGGGCTTAAAGCGCCCGTAGCCGGCCTGTAAAGTCACCGTTTAAAGACCCGGGCTCAACTCGGGGAACGGC-GGTGATACTTACA-GGCTAGGGGGCGGGAGAGGTCGGAGGTACTCCCGG-AGTAGGGGCGAAATCCTCAGATCCCGGGAGGACCACCAGTGGCGAAAGCGTCCGGCTAGAACGCGCCCGACGGTGAGGGGCGAAAGCCGGGGTAGCAAATAGGATTAGATACCCTAGTAGTCCCGGCTGTAAACGATGCAGGCTAGGTGGTGCCGCAGGAAAACTGGTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAAGGGGTGGA-ACCTGCGGCTCAATTGGAGTCAACGCCTGGAATCT-CACCGGGGGAGACCGCAG-GATGACGGCCGCTAACGACCTGAGAGGAGGTGCATGGCCGTCGCCAGCTCGTGTTGTGAAATGTCCGGTTAAGTCCGGCAACGAGCGAGACCCCCACTTCTAGTTGGTAACGGTCCACACTAGAAGGACTGCCGGTGT-TAAACCG-GAGGAAGGAGGGGGCCACGGCAGGTCAGCATGCCCCGAAACTTCCGGGCCGCACGCGGGTTACAATGGCAGGGACAGCGGGATCCGACCCCGAGAGGGGAAGGCAATCCCACAAACCCTGCCTCAGTTGGGATCGAGGGCTGAAACTCGCCCTCGTGAACGAGGAATCCCTAGTAACCGCGGGTCAAC-AACCCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCGCTCCACCCGAGTGGACGAGCTTCTCCTCCGCGAGGGGGGAGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGGCTCGGCTC-AGGGGCCTAAGAAGGGCGCGGCAAGCGGCGAAATGCCCAGGGGAGGCGC-ACGCAGCCTTAGATCCTGGGATCCCCGAATGGGACCCCCCGAACGGAAGCATCTTAGTAGGGGGAGGAGGAGAAATCAATT-GAGA-TTCCCTGAGTAGGGGCGACCGAAAGGGGAA-CAGCCCAAACAGCCGAAT-TCACCTGGAACATAGAGGGTGACAGCCCCGTAGGCGAA-CAGAGTACCATCCCCTG---GTTTGGGGGTGGGAAGATGGGAGACACG-TGCTTCCAAGGCTAAATACTTCCTGA-GACCGATAGCGAACTCAGTACTGTGAAGGAAAGCTGAAAAGCACCCCG-GAAGGGGAGTG-AAAAGTGCCTGAAACCGGGCGATTATCTTGCTTTTCGTCTTGAAACACGGGCCGGGGAGGTCA-CGTCAGTGGCGA-GCCTAAGAAGGCAAAGGGAAACCGAG-GATCCGCAAGTCAC-TGGCGTGAAACTAGAAACCGGGCGATCTAGACCTGGGCAGGTCGAAGTCGGG-GGAAACCCCGATGGAGGACCGAATAGGGGTTCTGACGTGCAATTCGTTCCCTTGACCTGGGTCTAGGGGCAAAAGACCAATCTAGCCCGG-TGATATCTAGTTCCCTCCGAAATGCGTCCTAGCGCAGCCTCCCTGGAGGTAGAGATACTGATTGG-TGACG-AAAGTCAGGGGAACCCAGTCAAACTCCGAAGG-AGT--GGATCACCCGGCGTAAGGTTGGG-TGGTAAGAG-GGGAACAACCCAGACCCG-GGTTAAGGTCCCCAAGTACTGGCT-AAGTGCG-AATCTGGAAGGGCGTCCCATGCCTAAGACAGCGGGAAGGTGGGCCCAGCAGCAGCCA-TCCTCTAAGGAGTGCGTAACAGCTCACCCGCC----GAGGCCTGGGGCCCTGCAGACTAGTCGGGGCTCAAGCCAGTCACCGATACCCGGGGTAGGGGG-GCGCCGCG-GTGGGCGAGAAGGT-GGGCCGTGAGGTCCACTGGAGCAGATCCCGGCGGCAGTA-ATAGCG-AAGGAGGGTGAGAATCCCTCCCGCC-GAAAGGGC-AAGGGTTTCCC-GGCAATG-TTCGTCAACCGGGAGTTAGCCGGTC--CTAAGGCAGGGCG--AAAGGGAAAGGGGTTAATATTCCCCTGCCCGGATCGAGGTAC-GGGAGAGCCGTATGGTGAGAAGGGGAC-GAAATCCTTGGTCCCCATGAAACGTACCCAGAACCGACACTGGTGCCCCTGGGTGAGAA-GCCCAAGGCGTCTGGGGGGTAACTCA-GGCTAGGGAACTCGGCAAAATGGTCCCGTACCTTCGGAAGAAGGGATGCCGTAGGTCGCAGTGACCAGGGGGATCTGACTATTTAATAAAAATATAGGTCCCCGCTAGCCCG-AAAGGGTGTGAACGGGGGCTAAATCCTGGCCACTGGCGGTCGGTTAAACCCGGGTCCAAAAGCCCCGCTGAAGGCCGGGGGTAACTCTGACCCTCTCAAGGTAGCCAAATGCCTTGCCGGGCAAGTTCCGGCGCGCATGAATGGATCAACGTGATCCCCACTGTCCCAGCCTGGGGCCCCATGACCGCCC--AGAGTGGGTTCACAGTCCCGCAACTCCTCACACCGAGAGAAGACCCCGTGGAGCTTCACCGCAGCCTGGCGCTGGGCGTTCATGCGTAGCGTAGGTGGGAGGCGTCG---AGAGCCGCAAGTGAAACACCACCCGACAACGTCAGGTGGGCGGTTCGGCTGGGGCGGCACTCCCGCGAAAAGATAACACGGGAGCCCAAAGGTCAGCTCAGGCGGTACAGAACGCCGCCGTAGAGTG-CAAGGGCAAAAGCTGGCCTGACGAGACCCTTCAAAGTACGGGGTCTCGACGCGAAAGCGCGGCCTAGCGAACGCTCATGC--CCCCACACGTGGGGGCTGGGCATGACAGA--AAAGTTACCCCGGGGATAACAGGGTCGTCGCGGGCGAGAG-CTCCCATCGACCCCGCGGTTTGCTACATCGATGTCGGCTCTTCCCACCCTGGAGGTGCAGCTGCCTCCAAGGGTAGGGCTGCCCGCCCGTTAAAGGGGAACGTGAGCTGGGTTTAGACCGTCGCGAGACAGGTCGGACTCTAAGGGTGAGGGGTGCA-CGCCGCCTGAGGGGAAGGTACTCCTAGTACGAGAGGAACAGGGTATCGGGGCCTCTAGTTTGCCGGTTGTCGGCA-GCGCCGGGCAGCCACGCCCTAGGGGG-TAACCGCTGAAAGCATCTAAGCGGGAACCCCTCCCCGAA-AAGAGGCGGCGAGCCCTCCCCAAGAACAGGGGGTTGATGGGGTGGGGGTGTAAGGGGTTCAGCCTGCCACTCCCAA
Methanobrevibacter_smithii_ATCC_35061                   GTTTGATCCTG-GCAGATGCTACTGCTATTGGGATTCGATTAAGCCATGCAAGTCGGCGTACGGCTCAGTAACACGTGGATAACCTACCCTTAGGACTGGGATAACCC--TGG-GAAACTGGGGATAATACTGGATAATGGTTTTTTGTTTAAACGCCTAAGGATGGGTCTGCGGCCGATTA-GGTAGTTGGTTAGGTAATGGCTTACCAAGCCTTTGATCGGTACGGGTTGTGAGAGCAA-GAGCCCGGAGATGGAACCTGAGACAAGGTTCCAGGCCCTACGGGGTGCAGCAGGCGCGAAACCTCCGCAATGTGAGAAATCGCGACGGGGGGATCCCAAGTGCTTTTCATTAGTGTAAAAATAAGAGCTGGGCAAG-ACCGGTGCCAGCCGCCGCGGTAACACCGGCAGCTCTAGTGGTAGCAGTTTTTATTGGGCCTAAAGCGTCCGTAGCCGGTTTAATAAGTCTCTGGTGAAATCCTGCAGCTTAACTGTGGGAATTGCTGGAGATACTATTA-GACTTGAGATCGGGAGAGGTTAGAGGTACTCCCAG-GGTAGAGGTGAAATTCTGTAATCCTGGGAGGACCGCCTGTTGCGAAGGCGTCTGACTGGAACGATTCTGACGGTGAGGGACGAAAGCTAGGGGCGCGAACCGGATTAGATACCCGGGTAGTCCTAGCTGTAAACGATGCGGACTTGGTGGTGCCGAAGGGAAGCTGTTAAGTCCGCCGCCTGGGAAGTACGGTCGCAAGACTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAACGCGTGGA-GCCTGCGGTTTAATTGGATTCAACGCCGGACATCT-CACCAGAGGCGACAGCTG-TATGATAGCCGTTGATGACTTGAGAGGAGGTGCATGGCCGCCGTCAGCTCGTACCGTGAGGCGTCCTGTTAAGTCAGGCAACGAGCGAGACCCACGCTCTTAGTTACCAGCCGGGCACACTAAGGGGACCGCCTATGA-TAAATAG-GAGGAAGGAGTGGACGACGGTAGGTCCGTATGCCCCGAATCCTCTGGGCAACACGCGGGCTACAATGGCTGAGACAATGGGTTCCGACGCCGAAAGGCGGAGGTAATCCTCTAAACTTAGTCGTAGTTCGGATTGAGGACTGTAACTCGTTCTCATGAAGCTGGAATGCGTAGTAATCGCGTGTCACA-ATCGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCACGCCACCCAAAAAGGCGAATCTAGTTTTTTTAAGGAGGGCGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCT----------------------------------------------------------------------------------------TCCGTGTA--ACCCGCCGAATTGAAACATCTTAGTAGGCGGAGGAAAAGAAAGCAATATGCGA-TGTCGTTAGTAACGGCGAGCGAAATCGACT-TAGAACAAACAATCGAATTTTATTTGGAACGTAGAGGGTGATAGTCCCGTAGATATACTTGAGTAGGATCCGTTG---GATATCGGGTTTGAATGTGGGAGGCATC-AACTTCCAATTCTAAATACGTCTCAA-GACCGATAGAGTATT-AGTACCGTGAGGGAATGCTGAAAAGTACCCCT-ATAGGGGGGTG-AAAAGTACCTGAAACCAGATAGTGATTGCATCGTCCGTCTTGAAACACGGGCCAGGGAGTTCT-TTGTTGTGGTGA-GGCTAAGTAGTCGTAGGGAAACCGATATGCCCGCAAATCAC-AGCATTGAAACCCGAAGCCGGTCGATCTATTCCTGAGCAGGATGAAGTCGCT-CTTACGAGCGATGGAGGTTCG--CAGGGTTGTTGTTCTGCAAAACACTCTTTTGACTTGGGAATAGTGGTGAAAGGCCAATCAAGGCCGG-CGACAGCTGGTTCCACTCGAAATGACTCTAAGGTCAGCCTGACTGGAGGTAGAG-CACTAATTGGGGAGGG-AAACTTCTCGGCGTACTGTAAAACTCCGAAGG-AGTGAGGGGCGC--GGGGTAAGCTTGTG-TCCCGAAAG-AGAAACAACTCAGACTAT-GGTTAAGGCCCCTAAATACTGGAT-AAGTGTA---------AGGGAGTCTTTGGCCCAAGACAATGGGAAGGTGGGCTTAGAAGCAGCCA-CCCTTTAACGAGTTCGTAACAGATCACCCATC----GAGGTCAGAGGCACCTAAAATGGAC-GGGAATTAATCCAGTTGCCGATACCATGGGTAGAGTG-GCGACCTG-TGTGGGTTGAAGAG-GGGGCGTGAGTTCCTTTGGAGTGGATCCTGGTAGTAGTA-GCAGCA-AAGTGAGGTGAGAATCCTTACCGCC-GGAGGGGC-TAGGGTTCCTT-GGCAATG-TTCGTCAGCCAAGGGTTAGTCGATC--CTAAGGTCAGTCG--AAAGGGAAGCAGGTTAATATTCCTGTACACACTTCGAGATAT-GGGAGAGGTGTATAGCGAGAACCAGGT-GTAATTCATGGAGTCCTTGAAACGTACCGAGATCCGTCACAGGTGCCCCTAGCTGAGTA-GGCTAAGGCGTTTTAAGGT-AAACTA-GCTAAGGGAAATCGGCAAAATGGCCCCGTAACTTTGGAAGAAGGGGTGCCGCTGGTCTCAGTGACTAGGGGGGCCCGACTGTTTAATAAAAACATAGCTCTCTGCTAGCCCG-TAAGGGTGTGTACAGAGGGCGACACCTGCCCAGTGCTGGCACGTGAAGCTGGAGTTCAGAAGCGCCAGTAAACGGCGGGGGTAACTATAACCCTCTTAAGGTAGCGAAATGCCTTGTCGGACAAGTACCGACCTGCATGAATGGTAGAACGAGGTCCCCACTGTCCCTAGCTAGAACTTAGTGAACCTGC--TATTCTGGTGCACAAGCCAGAGTCTTCCATTGGGAAGCGAAGACCCCGTAGAGTTTTACTGCAGTCTGTCGTTGGTTATAGGTATGCAGTGTAAGTGGGAGAATTCG---AGATTCGTTCTTGAGACACCACTTGACATCGGTAGATGGGCAGTTCGGCTGGGGCGGCACGGGCTTGAAATGGTATCAAGCCCGCCCAAAGGTCAACTCAGGTGGGACAGAGATCCACCGTAGAGTG-TAAGGGCAAAAGTTGGCCTGACTGTATTTCGATCAGCAAGAAATCCAGAGGCGAAAGCCGGGCCTAGCGAACCTCAGAGT--CCTCCTTGATGGGGGCCTGAGATGACAGA--AAAACTACCTCGGGGATAACTGGGTGGTCGCAGGCAAGAG-CCCATATCGACCCTGCGGCTTGCTACTTCGATGTCGGTTCTTTCCATCCTGGGTGTGCAGCAGCACCCAAGGGTGGGGTTGTTCGCCCATTAAAGGGGAACGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTTGGTTGCTATCTAATGGATGTGTT-AGTAGTCTGAGGGGAAGGTGGCTCCAGTACGAGAGGAACGAGTTGTCGGCGCCTCTGGTCGACCGGTTGTCGGCA-GTGCCGGGCAGCTACGCGCTAGGTGA-TAAAGGCTGAAAGCATCTAAGCCTGAGGTATCCCCTGAA-AATAGATTGCAGGAC-GCGAGTAGAAGACTTGTTTGATGGGGTAGGGATGTAAGTTGTTTAGTCCGCTACTTCCAA
Methanocaldococcus_jannaschii_DSM_2661                  GGTTGATCCTG-CCGGAGGCCACTGCTATCGGGGTCCGACTAAGCCATGCGAGTCGGCGCACGGCTCAGTAACACGTGGCTAACCTACCCTCGGGTGGGGGATAACCT--CGG-GAAACTGAGGCTAATCCCCCATAATGATCCCTCCCCGAAATGCCCGAGGATGGGGCTGCGGCGGATTA-GGTAGTTGGTGGGGTAACGGCCCACCAAGCCTACGATCCGTACGGGCCCTGAGAGGGG-GAGCCCGGAGATGGACACTGAGACACGGGTCCAGG-CCTACGGGGCGCAGCAGGCGCGAAACCTCCGCAATGCGCGAAAGCGCGACGGGGGGACCCCGAGTGCTTTTCCGGAGTGTAAAAATAAGGGCTGGGCAAG-TCCGGTGCCAGCAGCCGCGGTAATACCGGCGGCCCAAGTGGTGGCCACTGTTATTGGGCCTAAAGCGTCCGTAGCCGGCCCGGTAAGTCTCTGCTTAAATCTGC-GGCTCAACCGCAGGGCTGGC-AGAGATACTGCCG-GGCTTGGGACCGGGAGAGGCCGGGGGTACCCCAGG-GGTAGCGGTGAAATGCGTTGATCCCTGGGGGACCACCTGTGGCGAAGGCGCCCGGCTGGAACGGGTCCGACGGTGAGGGACGAAGGCCAGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCTGGCTGTAAACTCTGCGGACTAGGTGGTGCCGAAGGGAAGCCGTTAAGTCCGCCGCCTGGGGAGTACGGTCGCAAGACTGAAACTTAAAGGAATTGGCGGGGGAGCACTACAACGGGTGGA-GCCTGCGGTTTAATTGGATTCAACGCCGGGCATCT-TACCAGGGGCGACGGCAG-GATGAAGGCCGTTGACGACCTGAGAGGTGGTGCATGGCCGTCGTCAGCTCGTACCGTGAGGCGTCCTGTTAAGTCAGGTAACGAGCGAGACCCGTGCCCCATGTTGCTAGGAGGGCACTCATGGGGGACCGCCGGCGC-TAAGCCG-GAGGAAGGTGCGGGCAACGACAGGTCCGCATGCCCCGAATCCCCTGGGCTACACGCGGGCTACAATGGCCGGGACAATGGGACGCGACCCCGAAAGGGGGAGCGAATCCCCTAAACCCGGTCGTAGTCCGGATCGAGGGCTGTAACTCGCCCTCGTGAAGCCGGAATCCGTAGTAATCGCGCCTCACC-ATGGCGCGGTGAATGCGTCCCTGCTCCTTGCACACACCGCCCGTCACGCCACCCGAGTTGACGAACTTGGGTTCAGCGAGGGGGGCGAAGTCGTAACAAGGTAGCCGTAGGGGAA-CTGCGGCTGGATCACCTGGATGGCTCGGCTCGGGGCGCCGAGGAAGGGCGTGGCAAGCTGCGATAAGCCCGGGGGAGGCGC-AGGCAGCCGTGGAACCCGGGATCCCCGAATGGGACGCGGGGAAAAGAAGCATCCGAGTACCCGCAGGAAAAGAAACCAACA-GGGA-TGCCGGGAGTAGGGGCGACCGAAACCGGCA-CAGGGCAAACAGCCGAAG-TCCCCTGGAACATAGAGGGTGAAAGCCCCGTAGGCGTACCTGAGTACCGCGCGTTG---GATATCGCGCGGGAAGCTGGGAGACATTAGGCTTCCAACCCTAAATACGTCCCGA-GACCGATAGCGAACT-AGTACCGTGAGGGAAAGCTGAAAAGCACCCCT-TGCGGGGGGTG-AAAAGAGCCTGAAACCAGGTGGGTATCGTGCCGTCCGTTTCGAAAAACGGGCCGGGGAGTGTA-CGGGTGTGGCGA-GCCTAAGGAGGCGTAGGGAAACCGACATGCCCGCAAGTCAC-ACCCGTACGACCCGAAACCGGGCGATCTAGGCCGGGGTAGGGTGAAGCCCCT-CGCCAGAGGGGTGGAGGCCCG--CAGGGGTGTTACCGCGCAAAGTGCTCCTCTGACCCCGGTCTAGGGGTGAAAAGCCAATCGAGCCCGG-AGATAGCTGGTTCCCCCCGAAATAACTCGCAGGTTAGCCGGGGGTTAGGTAGAGCCACGGATAGGGGGGCG-AGAGCCCTCGGCACCCTGTCAAACTCCGAA---AGTGAGGGCATAC--GGGTAAGCCGTAT-GTCCGAGAG-GGGAACAACCCGGACCCG-GGTTAAGGCCCCTAAGTGCCGGCT-AAGTGTA--AATGAGAAGGGAGTCCCTGGCCTAAGACAGCGGGGAGGTTGGCTTAGAAGCAGCCA-TCCTTTAAAGAGTGCGTAACAGCTCACCCGTC----GAGGTCAGGGGCCCCGAAGAT-AACGGGGGCT-AAGCCGGCCGCCGAGACCCGGGGTAGGGGG-GCGTCCCG-CGGGGGTAGAAGCT-CGGCCGTGAGGTCGGGTGGAGAGAATCCCGGCAGTAGTA-ACAGCA-AAGTGGGGTGAGAATCCCCACCGCC-GAAGGGGC-CAGGTTTCCAC-AGCAACG-GTCGTCAGCTGTGGGTTAGCCGGTC--CTAACCCCCGGGG--AAAGGGAAGCGGGTTAATATTCCCGCGCCCGCTTCGGGGTAG-GGGAGTGCCGTATGGCGAGAACCGGGC-AAAAGCCCTGGAGCCCGTGAAACGTACCCAGAACCGACACAGGTGCCCCTAGGCGAGTA-TCCTAAGGCGTGTCGGGAG-AATCCG-GCCCAGGGAAGTCGGCAAATTGGCCCCGTAACTTCGGGAGAAGGGGTGCCGCAGGTCGCAGTGGCCAGGGGGGTCCGACTGTTTAATAAAAACACAGGTCTTGGCTAGCCCG-TAAGGGTGTGTACCAAGGCCGACGCCTGCCCAGTGCCGGTACGTGAAACCCGGGTACAAAAGCGCCGGTAAACGGCGGGGGTAACTATAACCCTCTTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCTGCATGAATGGCGTAACGAGACCCCCACTGTCCCGGGCCGGAACCCGGTGAACCTAC--CATTCCGGTGCAAAGGCCGGAGACCCCCAGTGGGAAGCGAAGACCCCGTGGAGCTTTACTGCAGCCTGTCGTTGGCCGTGGGTGCACAGCGTAGGTGGGAGCCGTCG---AGAGGCGCCCATGGGACACCACCCGACACCGGCAGGTGGGCAGTTTGGCTGGGGCGGCACCCCCCTGAAAAGGCATCAGGGGGGCCCAAAGGTCGGCTCAGGCGGGTCAGAACTCCGCCGTGGAGTG-CAAGGGCAAAAGCCGGCCTGACTTGGTCGGTAAAAGAGGCCGACCAAGAGGCGAAAGCCGGGCCTAGCGAACCCCTGTG---CCTCACCGATGGGGGCCAGGGATAACAGA--AAAGCTACCCCGGGGATAACAGAGTTGTCGCGGGCAAGAG-CCCATATCGACCCCGCGGCTTGCTACATCGATGTCGGTTCTTCCCATCCTGGGCCTGCAGCAGGGCCCAAGGGTGGGGCTGTTCGCCCATTAAAGGGGATCGTGAGCTGGGTTTAAACCGTCGTGAGACAGGTTGGTTGCTATCTGCTGGGGGTGTT-GGCCGCCTGAGGGGAAGGTGGCTCTAGTACGAGAGGAACGAGCCGCCGGCGCCTCTGGTCTACCGGTTGTCGGCA-TTGCCGGGCAGCTACGCGCTAAGGGA-TAAGGGCTGAAGGCATCTAAGCCCGAAACCCTCCCCGAA-AATAGGCGGCAGGGC-TCTCCTATAAGAGGAGGTTGATAGGCCGGGGGTGTA------------------------
Methanococcoides_burtonii_DSM_6242                      GGTTGATCCTG-CCAGAGGTTACTGCTATCGGTGTTCGACTAAGCCATGCGAGTCGGCGGACTGCTCAGTAACACGTGGATAACCTGCCCTTAGGTTTGGCATAACTC--CGG-GAAACTGGAGATAATTCCGAATAATGCTTTTTGATCAAAATGCCTAAGGATGGATCTGCGGTCTATCA-GGTTGTAGTGGGTGTAACGTACCTACTAGCCTACGACGGATATGGGTTGTGAGAGCAA-GAGCCCAGAGATGGATTCTGAGACATGAATCCAGGCCCTACGGGGCGCAGCAGGCGCGAAATCTTTACAATGCGGGAAACCGCGATAAGGGGACACCGAGTGCTGTCCACATGTGTAAAAGCAAGGGCCGGGCAAG-ACCGGTGCCAGCCGCCGCGGTAACACCGGCGGCCCGAGTGGTAATCACTTTTATTGGGTCTAAAGGGTCCGTAGCCGGTTTGATCAGTTCTTCGGGAAATCTGACAGCTCAACTGTTAGGCTTCCGGGGAATACTGTCA-GACTTGGGACCGGGAGAGGTAAGAGGTACTACAGG-GGTAGGAGTGAAATCTTGTAATCCCTGTGGGACCACCAGTGGCGAAGGCGTCTTACCAGAACGGGTCCGACGGTGAGGGACGAAAGCTGGGGGCACGAACCGGATTAGATACCCGGGTAGTCCCAGCCGTAAACGATGTTCGCTAGGTGGTGCCGTAGGGAAGCCGTGAAGCGAACCACCTGGGAAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACTACAACGGGTGGA-GCCTGCGGTTTAATTGGACTCAACGCCGGAAAACT-CACCGGGGGCGACAGCAA-AATGTAGGTCGCTAAAGACTTGAGAGGAGGTGCATGGCCGTCGTCAGTTCGTACTGTGAAGCATCCTGTTAAGTCAGGCAACGAGCGAGACCCGTGCCCACTGTTGCCAGATGGGTACTCTGTGGGGACCGCTGGTGC-TAAACCA-GAGGAAGGTGCGGGCTACGGTAGGTCAGTATGCCCCGAATCTCCCGGGCTACACGCGGGCTACAATGGTTGGGACAATGGGTTCCTACACCGAAAGGTGATGGCAATCTCCTAAACCCAACCGTAGTTCGAATTGAGGACTGTAACTCGTCCTCATGAAGCTGGAATCCGTAGTAATCGCGTTTCAAC-ATAGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCAAACCACCCGAGTGAGCGAACCTAAATTTCGCAAGGGGGGTTAAGTCGTAACAAGGTAGCCGTAGGGGAATCTGCGGCTGGATCACCTGGATGGCTCGGCTC-AAGCGCTGATGAAGGACGTGCCAAGCTGCGATAAGCTCAGGGTAGGTGC-ATGGAACCTATGAACCTGAGATTTCCTAATGAGACGCCCCGAATTGAAACATCTTAGTAGGGGCAGGAAGAGAAATCGAA--GAGA-TGCCGTTAGTAATGGCGAATGAACACGGCA-CAGTTCAAACAGCTGAAC-TTTTCTGGAACATAGAGTGTGATAGTCACGTAAGCAATCCTGAGTATCGTGTGTTG---GAAATCACGCGAGAATTTGGGAGGCACC-AACTTCCAAAACTAAATACGTCTTGA-GACCGATAGCGAAAT-AGTAGGGTGACCGAAAACTGAAAAGTACCCCCAAAAGGGAGGTT-AAAAGTGCCTGAAACCTGATGGTGATCATATCATACGTTTTGAAGAACGGGCCAGGGAGTGTA-ACTAAGTGGCGATGGCTAAGAAGCCGAAGCGAAAGCAACATGCGTGCAAGTCAC-TAAGTTACGACCCGAAGCCGGGTGATCTAGGCGTGGGCAGGTTGAAGCGTGG-CGAAAGCTACGTGGAGGACCG-CAAGCGGTATTGATCTGCAAATCATTCGTGTGACCTGCGTCTCGGAGTGAAAGGCTAATCTAACCCGG-CATCAGCTGGTTCCTTCCGAAACATGTCGTAGCATGACCTAACTGGAGGTAGAG-CACTGATTGAGGGAAG-AAATTCCTCATCCGTCTGTCAAACTCCGAAGG-AGTCCGGACTACT-GGGGTAAGCCTGTA-GTCCGTAAG-GGAGACAACCCAGCCCGT-GGTTAAGGTCCCTAAGTGTCGACT-AAGTGTT-AATACTAAAGGGCGTCCCAAGCCCTAGACAGCTGGAAGGTTAGCTTAGAAGCAGCTA-TCCTTTAAAGAGTGCGTAACAGCCCACCAGTC----GAGGTTTGGGGCCCCGAAAATGGAC-GGGGCTCAAGTCGACCACCGATACCACGGGTAGGAAG-GCGTTGCG-TTTGGGTAGAAGCA-GGGCTGTGAAGTCCTGTGGAGAAAATCCTGGTAATAGTA-GCAGCA-TAGTTAGGTGAGAATCCTAACCGCC-GAAGGGGC-TAGGTTTCCTC-GGCAATG-ATCGTCAGCCGAGGGTTAGTCGGTC--CTAAGTTGTACCA--AAAGGGAAACAGGTTAATATTCCTGTACTCGTTTTGGGGCAG-GGGAGAGCCGTATGGCGAGAAGCAGAC-GAACACCCCGGAACCCGTGAAACGTACCGAGATCTGACACAGGTGCCCCTAGCTGAAAA-GGCTAAGGCGTGTCGGAAT-AATTTG-GCTAAGGGAATTCGGCAAATTGGCTCCGTAACTTCGGGAGAAGGAGTGCCGCAGGTCGCAGTGACCAGGGAACTCTAACTGTCTAATATCAACATAGGAGATCGCAAACCCG-TAAGGGCTAGTACGATCTCTGAATCCTGCTCAGTGCAGGTACCTGAAACTTCGGTTCAAAAGGGCCTGTAAACAGCGGGGGTAACTATGACCCTCTTAAGGTAGCGTAGTACCTTGTCGCTTAATTGGCGACTTGCATGAATGGATCAATGAGAGTTCTACTGTCCCTAGCCAGAGTCCGGTGAAGCTTA--CATTCTAGTGCAGAGTCTAGAGACCTCTAGGGGGAAGTGAAGACCCCGTGGAGCTTTACTGCAGCCTGTCGCTGATTTTGGATGTACAGTGTAGGTAGGAGACGTCG---AGAGTCGCAATTGGGACACTACCCGACCCCGATAGGTGGGCAGTTTGCCTGGGGCGGGACGCCCTTGAAAAGATATCAAGGGCGCGCAATGGTTAACTCAAGTGGGTCGGAAACCTACTGAAGAGTG-CAAGAGCATAAGTTAGCCTGACGTGATTCAGCACAGTAGTGGATCACGAGACGAAAGTCGGTTCTAGCGAACCTTTATGT--CCCGCTTGGTGCGGGCTAAAGATGACAGA--AAAGTTACCCCGGGGATAATTGAGTCGTTGCCGGCAAGAG-CACATATCGACCCGGCAGCTTGCTACCTCGATGTCGGTTCTTTCCATCCTGGCTGTGCAGCAGCAGCCAAGGGTGAGGTTGTTCGCCTATTAAAGGAGATCGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGTTACTATCTACTAGAGGTGTA-TGTGGTCTGAGGGTAAGTTGCTTTTAGTACGAGAGGAACAGAGCAACGGCGCCACTGGTCGATCGGTTGTCGGCA-CTGCCGAGCAGCTACGCGCTAAGGAA-TAAGAGCTGAATGCATCTAAGCTCGAAATCTAACCTAAA-AAGAGACCACAGGGT-TCCGGTAAAAGACCGGATCGATAGGAATGGGATGTAAGGTGTTCAGTCCGCATTTACTAA
Methanococcus_maripaludis_s2                            GGTTGATCCCG-CCGGAGGCCACTGCTATTGGGATTCGACTAAGCCATGCGAGTCGGCGGACGGCTCATTAACACGTGGTTAACATACCCTCAGGTGGGGGATAACCT--TGG-GAAACTGAGGATAATACCCCATAATGATTCTTTTTCGAAACGCCTGAGGATTGGACTGCGCTCGATTA-GGTAGTTGGTGGGGTAATGGCCCACCAAGCCTACGATCGGTACGGGCCTTGAGAGAGG-GAGCCCGGAGATGGGGACTGAGACACGGCCCCAGGCCCTACGGGGCGCAGCAGGCGCGAAACCTCCGCAATGCACGAAAGTGCGACGGGGGGATCCCAAGTGCTTTTATCAAGTGTAAAAATAAGGGCTGGGCAAG-TTCGGTGCCAGCAGCCGCGGTAACACCGACGGCCCAAGTGGTGGCCACTCTTATTGGGCCTAAAGCGTCCGTAGCCGGTCCAGTAAGTCCCTGTTTAAATCCTGCGGCTTAACCGCAGGACTGGC-AGGGATACTGCTG-GACTTGGGACCGGGAGAGGACAAGGGTACTTCAGG-GGTAGCGGTGAAATGTGTTGATCCTTGAAGGACCACCTATGGCGAAGGCACTTGTCTGGAACGGGTCCGACGGTGAGGGACGAAAGCCAGGGGCGCGAACCGGATTAGATACCCGGGTAGTCCTGGCCGTAAACTCTGCGAACTAGGTGGTGCCGAAGGGAAGCCGTTAAGTTCGCCGCCTGGGGAGTACGGTCGCAAGACTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAACGGGTGGA-GCCTGCGGTTTAATTGGATTCAACGCCGGGCATCT-CACCAGGAGCGACAGCAT-GATGACGGCCGTTGACGACCTGAGAGGTGGTGCATGGCCATCGTCAGCTCGTACCGCGAGGCGTCCTGTTAAGTCAGGTAACGAGCGAGACCCGTGCCCTATGTTGCTA---AGGCACTCATAGGGGACCGCTGGCGC-TAAGTCA-GAGGAAGGAGCGGGCAACGATAGGTCCGCATGCCCCGAATCTCCTGGGCTACACGCGGGCTACAATGGCTAGGACAATGGGCCGCAACCCTGAAAAGGGACGCAAATCTCCTAAACCTAGTCGTAGTTCGGATCGTGGGCTGTAACTCGCCCACGTGAAGCTGGAATCCGTAGTAATCGCAGTTCATA-ATACTGCGGTGAATGTGTCCCTGCTCCTTGCACACACCGCCCGTCACACCACCCGAGTTGGCGAACTTGGGCTCAGCGAGGGGGGTGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGAATGGCTTGGCTTGGAACGCCGATGAAGGACGTGGTAAGCTGCGATAAGCCCAGGCGAGACGC-ATACAGTCATTGAACCTGGGATTTCCGAATGGGACGCGGGGGATTGAAGCATCTTAGTACCCGCAGGAAGAGAAATCAATA-GAGA-TTCCGTTATTAGAGGCGATTGAACGCGGAT-CAGAGCAAACAGCTGAAG-TTGACTGGAATATAGAGGGTGAAAGTCCCGTAAGCGTACCTGAGTACCGTGCGTTG---GATATCGCGCGGGAATTTGGGAGGCATC-AACTTCCAACTCTAAATACGTTCCAA-GACCGATAGTGTACT-AGTACCGCGAGGGAAAGCTGAAAAGCACCTTT-AATCGGGTGTG-AAAAGAGCCTGAAACCAGATAGGTATTGTGTCGTCCGTTTCGAAAAACGGGCCGGGGAGTATA-TTGTTGTGGCGA-GCTTAAGTAGGCGTAGGGAAACCAACAAGTCCGCAAGTCAC-AGCAATATGACCCGAAACCGGGCGATCTAGGCCGGGGCAAGGTGAAGTCCCT-CAACTGAGGGATGGAGGCCTG--CAGAGTTGTTGCCGTTCGAAGCACTCTTCTGACCTCGGTCTAGGGGTGAAAGGCCAATCGAGCCCGG-AGATAGCTGGTTCCCTCCGAAGTGACTCTCAGGTCAGCCGGAGTTTAGGTAGAG-CACTGATAAGGGGAAG-AAATTCCTCGCTGTTTTGTCAAACTCCGAACG-AGTGAGGGCATAC--GGGTAAGCTGTAT-GTCCGAGAC-GGGAATAGCCGAGACTTG-GGTTAAGGCCCCTAAGTGCCGATT-AAGTGTG--AACACGAAGGGCGTCCTTGGTCTAAGACAGCAGGGAGGTTGGCTTAGAAGCAGCCA-TCCTTTAACGAGTGCGTAACAGCTCACCTGTC----GAGATCAAGGGCCCCGAAAATGGAC-GGGGCT-AAATCGGCCGCCGAGACCCAAGGTAGGGGG-GCGTTCTG-CGAGGGCAGAAGTT-CGGCTGTGAAGTCGAGTGGAGAAGATCCCGGTAGTAGTA-ACAGCATAAGTGGGGTGAGAATCCCCACCGCC-GAAGGGGC-AAGGGTTCCAC-AGCAATG-TTTGTCAGCTGTGGGTAAGCCGGTC--CTAACTCTCGAGG--AAAGGGAAACAGGTTAATATTCCTGTGCCCGCTTCTGGGTAG-GGGAGAGTTGTATAACGAGAACCGGAT-GAAATCTCTGGAGCCCGTGAAACGTACCCAGAACCGACACTGGTGCCCCTAGGTGAGTA-TCCTAAGGCGTAGCGGATG-AATCTA-GTCGAGGGAAGTCGGCAAATTGGCTCCGTAACTTCGGGAGAAGGAGTGCCGCTGGTCGCAGTGACCAGGGAGGTCCGACTGTTTAATACAAACATAGGTCTTAGCGAGCCTG-AAAAGGTGTGTACTAAGGCCGACGCCTGCCCAGTGCTGGTACGTGAACCCCGGTTCCAAAAGCGCCAGTAAACGGCGGGGGTAACTATAACCCTCTTAAGGTAGCGAAATTCCTTGTCGGGCAAGTTCCGACCTGCATGAATGGCGTAACGAGACCTCCACTGTCCCCGACTAGAATCCGGTGAACCTAC--CATTCCGGCGCAAAGGCCGGAGACTTCCAGTGGGAAGCGAAGACCCCGTGGAGCTTTACTGCAGCCTGTCGTTGGTTGTGAGTGTACAGTGTAGGTGGGAGCCATCG---AGAGGCGATCCTGGGACACCACCCGACACCGGTAGGTGGGCAGTTTGGCTGGGGCGGTACCCTCCTAAAAATGCATCAGGAGGGCCCAAAGGTTGGCTCAAGCGGGTCAGGACTCCGCTGTTGAGTG-TAAGGGCAAAAGCCAGCCTGACTTTGTTGCCAACAAAACGCAACGAAGAGGCGAAAGCCGGGCCTAACGAACCCCTGTG---CCTCACTGATGGGGGCCAGGGATGACAAA--AAAGCTACCCCGGGGATAACAGAGTTGTCGCGGGCAAGAG-CCCATATCGACCCCGCGGCTTGCTACCTCGATGTCGGTTTTTCCCATCCTGGGTCTGCAGCAGGACCCAAGGGTGGGGCTGTTCGCCCATTAAAGGGGATCATGAGCTGGGTTTAGACCGTCGTGAGACAGGTTGGTTGCTATCTGCTGGATGTGTT-GGCTGTCTGAGGGAAAGGTGGCTCTAGTACGAGAGGAACGGGCCGTCGGCGCCTCTAGTCGATCGGTTGTCGGCA-TTGCCGAGCAGCCACGCGCCAAGAGA-TAAGAGCTGAAAGCATCTAAGCTCGAAATTCATCCTGAA-AATAGACAGCAGAAC-TCCCGTAGAAGACGGGTTTGATAGGCTAGGGGTGTAAGATGTTCAGCCCGCTAGTACTAA
Methanococcus_voltae_A3                                 GGTTGATCCCG-CCGGAGGTCACTGCTATTGGGGTTCGACTAAGCCATGCGAGTCGGCGGACGGCTCATTATCACGTGGTTAACTTACCCTCAAGCGGAGGATAACCT--TGG-GAAACTGAGGATAATACTCCATAATAATCTTTTTCTGAAACGCTTGAG?ATAGGACTGCGCTCGATTA-GGTAGTTGGTGGGGTAATGGCCCACCAAGCCTACGATCGATACGGGCCTTGAGAGAGG-GAGCCCGGAGATGGGGACTGAGACACGGCCCCAGGCCCTACGGGGCGCAGCAGGCGCGAAACCTCCGCAATGCACGAAAGTGCGACGGGGGGACCCCAAGTGCTTTTAGTAAGTGTAAAAATAAGGGCTGGGCAAG-TTCGGTGCCAGCAGCCGCGGTAACACCGACGGCCCAAGTGGTGACCACTCTTATTGGGTCTAAAGCGTCCGTAGCCGGTTTAGTAAGTCCTTGTTTAAATCCTCTGGCTTAACCAGAG?ACTGGC-AGGGATACTGCTA-GACTTGGGACCGGGAGAGGACAAGGGTACTCCAAG-GGTAGCGGTGGAATGTGTTGATCCTTGGAGGACCACCTATGGCGAAGGCACTTGTCTGGAACGGGTCCGACGGTGAGGGAC??AAGCCAGGGGCGCGAACCGGATTAGATACCCGGGTAGTCCTGGCCGTAAACTTTGCGAACTAGGTGGTGCCGAAGGGAAGCCGTTAAGTTCGCCACCTGGGGAGTACGGTCGCAAGACTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAACGGGTGGA-G?CTGCGGTTTAATTGGATTCAACGCCGGGCATCT-CACCAGGAGCGACAGCAT-TATGATGACCGTTGACGACCTGAGAGGTGG?GCATGGCCATCGTCAGCTCGTACCGCGAGGCGTCCTGTTAAGTCAGGTAACGAGCGAGACCCGTGCCCTATGTTGCTAG?ACAGCACTCATAGGAGACCG?TGGCGC-TAAGTCA-GAGGAAGGAGCGGGCAACGATAGGTCCGCATGCCCCGAATCTCCTGGGCTACACGCGGGCTACAATGGCTGGGACAATGGGATGCTACCCTGAAAAGGGACGCAAATCTCCTAAACCCTGTCGTAGTTCGGATCGTGGGCTGTAACTCGCCCACGTGAAGCTGGAATCCGTAGTAATCGCAGTTCATA-ATACTGCGGTGAATGTGTCCCTGCTCCTTGCACACACCGCCCGTCACACCATCCGAGTTGGCGAACCTGGGTTCAGC?AGGAGGG???????GTAACAAG????????????GAACCTG??????GATCACCTGAATGGCTTGGCTTGGAACGCCGACGAAGGACGTGGTAAGCTGCGATAAGCTTAGGCGAGGTGC-ATACAACCTTTGAACCTAAGATTTCCTAATGGGACGCGGGGAATTGAAGCATCTTAGTACCCGCAGGAAGAGAAATCAAAT-GAGA-TTCCGTGATTAGAGGCGATTGAAAGCGGAT-TAGGGCAAACAACTGAAG-TTGACTGGAACATAGAGGGTGAAAGTCCCGTAAGTGAACCTGAGTACCGTGCGTTG---GATATCGCGCGGGAAATTGGGAGGCATC-GACTTCCAACCCTAAATACGTTCCAA-GACCGATAGCGTATT-AGTACCGCGAGGGAAAGCTGAAAAGTATCCTT-AATAGGATGTG-AAAAGTGCCTGAAACCAAGTAGGTATTGTGTCGTCCGTTTCGAAAAACGGGCCGGGGAGTGTA-TTGTTGTGGCGA-GCTTAAGTAGGCGAAGGGAAACCAACAAGTTCGCAAGTCAC-AGCGATACGACCCGAAACCGGGCGATCTAGGCCAGGGCAAGGTGAAGTCCCT-CAACTGAGGGATGGAGGCCTG--CAGAGGTGTTGCCGTTCGAAGCACTCTTCTGACCTTGGTCTAGGGGTGAAAGGCCAATCGAGCCCGG-AAATAGCTGGTTCCCCCCGAAGTGACTCTCAGGTCAGCCGAAGTTTAGGTAGAG-CACTGATAGGGGGAAG-AAATTCCTCGCTTTTCTGTCAAACTCCGAA---AGTCAGGGCATAC--GGGTAAGCTGTAT-GTCCGAGAC-GGGAATAGCCGTGACCTG-GGTTAAGGTCCCTAAGTGCCGATT-AAGTGTG--AACACGAAGGGTGTCCTTGGTCTAAGACAGCAGGGAGGTTGGCTTAGAAGCAGCCA-TCCTTTAACGAGTGCGTAACAGCTCACCTGTC----GAGATCAAGGGTCCCGAAAATGGAC-GGGGCTAAAATCGGCCACCGAGACCCAGGGTAGGGGG-GCGTTCTG-CGAGGGCAGAAGTT-CGGCTGTGAAGTCGAGTGGAGATGATCCCGGTAGTAGTA-ACAGCATAAGTGGGGTGAGAATCCCCACCGCC-GAAGGGGC-AAGGGTTCCAC-AGCAATG-TTCGTCAGCTGTGGGTAAGCCGGTC--CTAACTCTCGAGG--AAAGGGAAACAGGTTAATATTCCTGTGCCCGCTTTGGGATAA-GGGAGAATTGTATAATGAGAATCGGAT-GAAATTCCTTGAGCCCGTGAAACGTACCCAGAACCGACACTGGTGCCCCTAGGTGAGTA-TCCTAAGGCGTAGCGGAAT-AATCTA-GTCGAGGGAAGTCGGCAAAATGGCTCCGTAACTTCGGGAGAAGGAGTGCCGCTGGTCGCAGTGACCAGGGAGGTCCGACTGTTTAATACAAACATAGGTCTTAGCGAGCCTG-AAAAGGTGTGTACTAAGGCCGACGCCTGCCCAGTGCTGGTACGTGAACCCCGGTTCCAAAAGCGCCAGTAAACGGCGGGGGTAACTATAACCCTCTTAAGGTAGCGAAATTCCTTGTCGGGCAAGTTCCGACCTGCATGAATGGCGTAACGAGACCTCCACTGTCCCCGACTAGACTCCGGTGAACCTAC--CATTCCGGCGCAAAGGCCGGAGACGTCCAGTGGGAAGCGAAGACCCCGTGGAGCTTTACTGCAGCCTGTCGTTGATTGTGGGTGTACAGTGTAGGTGGGAGCCATCG---AGAGGCATCCATGGGACACCACCCGACACCGGTAGGTGGGCAGTTTGGCTGGGGCGGTACCCTCCTAAAAATGCATCAGGAGGGCCCAAAGGTTGGCTCAAGCGGGTCAGGACTCCGCTGTTGAGTG-TAAGGGCAAAAGCCAGCCTGACTTTGTTGCCAACAAAACGCAACGAAGAGACGAAAGTCGGGCCTAACGAACCTCTGTG---CCTCACCGATGGGGGCCAGAGATGACAAA--AAAGCTACCCCGGGGATAACAGAGTTGTCGCGGGCAAGAG-CCCATATCGACCCCGCGGCTTGCTACCTCGATGTCGGTTTTTCCCATCCTGGGTCTGCAGCAGGACCCAAGGGTGGGGCTGTTCGCCCATTAAAGGGGATCATGAGCTGGGTTTAGACCGTCGTGAGACAGGTTGGTTGCTATCTGCTGGATGTGTT-GGCTGTCTGAGGGAAAGGTGGCTCTAGTACGAGAGGAACGGGCCGTCGGTGCCTCTAGTCGATCGGTTGTCGGCA-TTGCCGAGCAGCCACGCACCAAGAGA-TAAGGGCTGAAAGCATCTAAGCCCGAAGTTCATCCTGAA-AATAGACAGCAGGAC-TCCCATAGAACATGGGTTTGATAGGTTAGGGGTGTAAGGCATTAAGCCCGCTAATACTAA
Methanocorpusculum_labreanum_Z                          GGTTGATCCTG-CCAGAGGCCATTGCTATCAGGGTTTGACTAAGCCATGCGAGTCGGCATACTGCTCAGTAACACGTGGTTAACCTGCCCTAAGGTGGAGAATACTCC--CGG-GAAACTGGGGCTAATGCTCCATAATGGTATATCCTCGAAACGCCTTAGGATGGGACTGCGTCCGATTA-GGTTGTTGGCGGGGTAACGGCCCACCAAGCCTTTTATCGGTACGGGTTGTGGGAGCAA-GATCCCGGAGATGGATTCTGAGACATGAATCCAGGCCCTACGGGGCGCAGCAGGCGCGCAAACTTTACAATGCGAGCAATCGTGATAAGGAAACCCTGAGTGCTGTTCATATATCTAAAAGAAAGGGCAGGGCAAG-ACCGGTGCCAGCCGCCGCGGTAATACCGGCTGCTCGAGTGATGGCCACTATTACTGGGTTTAAAGCGTCCGTAGCTTGACTGTTAGGTCTCTTGGGAAATCTTCGCGCTCAACGTGAAGGCGTCTAAGAGATACCGGCA-GTCTTGGAACTGGGAGAGGTAAACCGTACTTCGGG-GGTAGGAGTGAAATCTTGTAATCCTCGAGGGACGACCTATGGCGAAGGCAGTTTACCAGAACAGCTTCGACAGTGAGGGACGAAAGCTGGGGGAGCAAACGGGATTAGATACCCCGGTAGTCCCAGCCGTAAACAATGTGCGTTAGGTGGCGCCGAAGAGAAATCGTGAAACGCACCACCTGGGAAGTACGGTCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAACAGGTGGA-GCCTGCGGTTTAATTGGATTCAACGCCGGACATCT-CACCGGATAAGACAGCTG-AATGATTGTCTCTGAAGGTTTGAGAGGAGGTGCATGGCCGTCGTCAGTTCGTACTGTGAAGCATCCTGTTAAGTCAGGCAACGAGCGAGACCCACGCCGACAATTGCCAGCTGGGGACATTGTCGGGACCGCCTCTGC-TAAAGGG-GAGGAAGGAATGGGCAACGGTAGGTCAGCATGCCCCGAATTATCCGGGCTACACGCGGGCTACAATGGACGGGACAATGGGTAACAACACCGAAAGGTGCAGTCAATCTCCGAACCCCGCCCTTAGTTAGGATTGCGGGTTGCAACTCACCCGCATGAATCTGGAATCTGTAGTAATCGCGTTTCACT-ATAGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCAAACCATCCTAGTGGGCGAATCTAGGTTCCGTGAGGAGGGTTAAGTCGTAACAAGGTAGCCGTAGGGGAATCTGCGGCTGGATCACCTGAATGGTTCGGTTT-GAGAGCTGATGAAGGGCGTGCCAAGCAGCGAAATGCCCCGGGAAGACGC-AAGGAGTCTGTGATCCGGGGATCCCCTAATAGGACCCCCCGAAGTGAAACATCTCAGTAGGGGGAGGAAGAGAAATCAATT-GAGA-TTACGTTAGTAGAGGCGATCGAACCCGTAA-TAGTCTAAACAATGAAAG-TAGCTTGGAACTTAGAGGGTGACAGTCCCGTACGTGGTCCTGAGTAGCGCGGGTTG---GAATTCCCACGTGAATATGGGGGTCACCTAACCTCCAAGACTAAATACTCCTCAA-AACCGATAGCGAAAT-AGTAGCGTGAGCGAAAACTGAAAAGTATCCCTGAAAAGGAAATG-AAAAGTGCCTGAAACTAACCGGTGATCGTAACTTACGTTTTGAAGAACGGGCCAAAGAGTGTA-TTCCGCTGGCGA-GGTTAAGCAGCCGCAGCGAAAGCGACAAGCGCGTAAGTCAA-CGGGATACGACCTGAAACCTGGTGATCTATGCCTGAGCAGGTTGAAGCGTGC-CGAAAGGTGCGTGGAGGACCG-CATGCGGTATTGATATGCAAATCATTCGCGTGACTTGGGTATAGGAGTGAAAGATTCATCGAACCGGG-TGTCAGCTGGTTCCTCTCGAAACATGTCTAAGCATGACCTCGACCGAGGTAGAG-CACCTATTGGGGGAAG-AAATTCCTCGCTTTCCTGTAAAACTCCAAAGGCAGTCCGGGCTAC--GGGGTAAGCTTGTA-GTCCGTAAG-GGAGACAACCCAGACCAT-GGTTAATGCCCCCCAATGTAGGCT-AAGTGTC-AACACTGAATGAAGTCCTAGGTCAAAGACAACTGGAAGGTGAGCTCAGAAGCAGCTA-TCCTTTAAAAAGTGCGTAACAGCTTACCAGTC----AAGATTTAGGGCGCAGAAAATGGAC-GGGGCTCAAGCCTACTGCAGATACCATGGGTAGAGAG-GCGTCCTG-TATGGGCTGAAGCA-GGGGTGTAAGTTCCTGTGGAGAGAATTTTGGCAGTAGTA-GAAGCA-AAGAATGGTGAGAATCCATTCCGCC-GAAGGGGC-TAGGTTTCCTC-GGCAATG-TTCGTCAGCCGAGGGTTAGTCGGTC--CTAAGCTGCATCA--AAAGGGAAACAGGTTAATATTCCTGTACCCGCATCGGGTTAT-GGGAGTACCGTATGGTGAGAATTGAGT-GAAACACCTGGTGCCCGTGAAACGTACCGAGAACCGACACAGGTGCCCCTAGTTGAAAA-GACTCAGGCGTGTCGGAATTATTTGT-GGTAAGGGAACTCGGCAAAATGGCTCCGTACCTTCGGAACAAGGAGTGCCGCAGGTCGCAGTGACCAGGGAGCTCTAACTGTCTAACAACAACATAGCAGACTGCAACTCCG-TAAGGACTAGTATAGTCTGTGAATCCTGCCCAGTGCGGGTATCTGAACACTGATTACAAAAGGACCCGTAAACGGCGGGGGTAACTATGACCCTCTTAAGGTAGCGTAGTACCTTGTCGCTTAATTGGCGACTTGCATGAATGGATTAATAAGGGCTCTACTGTCCCTACCGCAAATCCGTTGAACCTTT--TATCCTTGTGCAGAGGCAAGGGACTCCCATCGGGAAGTGAAGACCCCATGGAGCTTTACTGCAGCCTGTCGTTGGTATTACATGCGCAGCGTAGATAGTAGGTGTTA---AGAGCCACAGTTGAGACACTATCCGACATCGGTAGGTAGGCAGTTTGGGTGGGGCGCCACACCCTCGAAAAAATATCAAGGGTGCCCTATGGTCAACTCATGTGAGTCAGCAACTCACAGGAGAGTGTCAAGAGCATAAGTTGGCTTGACGTGATTTCGCATAGCAAGAAATCACGAGTGGAAACACGGGTCTAACGAACCAATACG---CCTTTTTGGTGAGGGCTATTGACTACAGA--AAAGCTACCCTGGGGATAACAGAGTCGTCGCCGGCAAGAG-CACATATCGACCCGGCGGCTTGCTACCTCGATGTCGGTTCTTTCCATCCTGGCTGTGCAGCAGCAGCCAAGGGTGAGGTTGTTCGCCTATTAAAGGGGATCGTGAGCTGGGTTCAGACCGTCGTGAGACAGGTCGGTTACTATCTGATGGGAGTGTT-CGAAATCTGAGAGCAAGAATGAAATAGTACGAGAGGAACTTTCATTCGTCACCTCTGGTGTATCGGTTGTCGGCA-GTGCCGAGCAGCTACGTGGCACGAGA-TAAAAACTGAAAGCATCTAAGTTTGAAACTTCGCTTGAA-AAGAGATTTCAGAGC-ACCGGTAAAAGACCGGGTTAATAGGCTTGGGATGTAACGTGTTTAGTCCGCAAGTACTAA
Methanopyrus_kandleri_AV19                              GGTTGATCCTG-CCGGAGGCCACCGCTATCGGGGTCCGACTAAGCCATGCAAGTCGGCGGACGGCTCAGTAACACGTGGGTAACCTACCCTCGGGACGGGGATAACCC--CGGCGAAAGTGGGGCTAATCCCCGATAACGGTCCTCCGCCGAAACGCCCGAGGATGGGCCTGCGGCCGATTA-GGTAGTTGGCGGGGTAACGGCCCGCCAAGCCGATAATCGGTACGGGCGGTGAGAGCCG-GAGCCCGGAGACGGGGACTGAGACAAGGCCCCGGGCCCTACGGGGCGCAGCAGGCGCGAAACCTCCGCAATGCGGGCAACCGCGACGGGGGGACCCCGAGTGCTGTACCGGGGTGTAAAAGAAAGCGGCGGGCAAG-ACCGCTGCCAGCCGCCGCGGTAATAGCGGCGCCGCAAGTGGTGGCCGCTTTTATTGGGCCTAAAGGGGCCGTAGCCGGTCCCGTGGGTCCCCGCCGAAAGCCCGCGGCTTAACCGCGGGAGTCGGCGGGGAAACTGCGG-GACTTGGGACCGGGAGAGGCCGGAGGTACCCCCGG-GGTAGGGGTGAAATCCTGTCATCCCGGGGGGACCGCCAGTGGCGAAGGCGTCCGGCTGGAACGGGTCCGACGGTGAGGGCCGAAAGCCGGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCCGGCTGTAAACGATGCGGACTAGGTGGTGCCGTAGGGAAGCCGTTAAGTCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAACCGGTGGA-GCCTGCGGTTTAATTGGATTCAACGCCGGAAACCT-TACCGGGGGCGACAGCAG-GATGAAGGCCGTTGACGACCTGAGAGGAGGTGCATGGCCGCCGTCAGCTCGTGCCGTGAGGTGTCCTGTTAAGTCAGGTAACGAGCGAGACCCCCGCCCGCAGTTGCCAGCCGGGCACTCTGCGGGGATCGCCGCCGT-TAAGGCG-GATGAAAGTGGGGGCGACGGCAGGTCCGTATGCCCCGAAACCCCCGGGCTACACGCGGGCTACAATGGCGGGGACAATGGGATCCGACCCCGAAAGGGGGAGGAAATCCCCTAAACCCCGTCGTAGTTCGGATTGCGGGCTGCAACTCGCCCGCATGAAGGTGGAATCGGTAGTAACCGTGCCTCAGA-ATGGCACGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCACGCCACCCGAGCCCCCGAGCCCCCGGGGGGTGAGGGGGGCGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGCCTTGGCTC-GGGCGCCGAGGAAGGCCGTGGCAAGCTGCGATAAGCCCGGGCGAGGCGC-ATGCAGCCGTGGAACCCGGGATCGCCGAATGGGACCCGCCGAACTGAAACATCTTAGTAGGCGGAGGAAAAGAAAGCAACACGCGA-TGCCGTGAGTAGGGGCGACCGAAAACGGCA-GAGGGCAAACGGCCGAAG-TGCCCTGGAACGGAGAGGGTGACAGCCCCGTAGGCCGCCCTGAGTACCGTCGGTTG---GATATCCGGCGGGAATCTGGGGGACATC-GGCCCCCAACCCTAAATACGTCCCGA-GTCCGATAGCGAACA-AGTACCGTGAGGGAAAGGTGAAAAGAACCCCG-GAAGGGGAGTG-AAAAGAGCCTGAAACCCGACGGCGATCCCGGCGTTCGTTTTGAAACACGAGGCGGGGAGTCCG-CGGCCGCGGCGA-GTCTAAGAAGGCGTAGGGAAACCGACACGCCCGCAAGCCGC-GGCCGCGGGACCCGAAACCGGCCGATCTAGCCCGGGGCAGGGTGAAGCGGCC-CTAAAGGGCCGTGGAGGCCCG-CTAGGGGTGCTGTAGTGCAAAACGCTCCCGTGACCCCGGGCTAGGGGTGAAAGGCCAATCGAGGCCGG-AGACAGCTGGTTCCCCCCGAAACGGCCCGCAGGTCGGCCCGGCCGGAGGTAGAG-CACTGATTCCGGGCCG-AGAGGCCCCGCCGGGGAGTCAAACTCCGAAGG-AGTTGGGGCCGGC--GGGTAAGCCGCCG-GTCTGAGAG-GGGAATAACCCAGACCGG-GGTTAAGGCCCCAAAGTGCCGGCT-AAGTGTT-AAATAGAAAGGGAGTCCCCGGCCGAAGACAGCGGGGAGGTAGGCTTAGAAGCAGCCA-TCCTTTAAAGAGTGCGTAACAGCTCACCCGTC----GAGGTCGGGGGCCCCGAAAATGGAC-GGGGCTGAAGCCGGCCGCCGAGACCCCGGGTAGGGGG-GCGCCCCG-GCGGCTCAGAAGCC-GGGCCGTGAGGTCCGGTGGAGAGAATCCCGCCGGTAGTA-GCAGCA-AAGCGGGGTGAGAATCCCCGCCGCC-GGAGGGGC-CAGGGTTCCTC-GGCAATG-TTCGTCAGCCGAGGGTAAGTCGGCC--CTAAGGCCGGCGG--AAAGGGAAACGGGTTAATATTCCCGTACCCGCCTCGGGGTAG-GGGAGTCCCGTATGGGGAGAACCGGCC-GAAATCCCCGGGGCCCGTGAAACGTACCGAGAACCGACACAGGTGCCCCTGGGTGAGAA-GCCTAAGGCGCGGCGGGGT-AACCCG-GCCGAGGGAAATCGGCAAATTGGCCCCGTAACTTCGGGAGAAGGGGTGCCGCGGGTCGCAGTGACTAGGGGGGGCCGACTGTTTAATAAAAACATAGGTCCCGGCTAGCCCG-AAAGGGCTGGTACCGGGGCCGACGCCTGCCCAGTGCCGGTACGTGAAGCCCGGGTACAAAAGCGCCGGTAAACGGCGGGGGTAACTATAACCCTCTTAAGGTAGCGAAATGCCTTGCCGGTTAAGTACCGGCTTGCATGAATGGCGTAACGAGCCCCCCACTGTCCCCGGCCGGGACCCGGTGAACCCGC--CATCCCCGTGCAGAGGCGGGGGACCCCCGGCGGGAAGCGAAGACCCCGTGGAGCTTTACCGCAGCCTGCCGTTGGCTGCGGGTGTATAGCGTAGGTGGGAGCCGTTACTCAGAGGCGCCCATGGAACACCACCCGACAGCGGTTGGTGGGCGGTTTGGCTGGGGCGGCACGCCCCCGAGAAGGCATCGGGGGCGCCCAAAGGTCGGCTCAGGCGGGTCAGAAATCCGCCGTAGAGTG-CAAGGGCAAAAGCCGGCCTGACTGGGTCCCGCACAATAAGGGACCCAGGCGGGAAACCGTGGCCTAGCGAACCCCGGTG---CCGCCCCGGTGGCGGCCCGGGATGACAGA--AAAGCTACCCCGGGGATAACAGGGTGGTCGCGGGCAAGAG-CCCACATCGACCCCGCGGCTTGCTACCTCGATGTCGGCTCTCCCCATCCTGGCGGTGCAGCAGCCGCCAAGGGTGGGGTTGTTCGCCCATTAAAGGGGAACGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGTCGCTATCTGCCGGGGGTGTT-GGCCGCCTGAGGGGAAGGACCGCCTAGTACGAGAGGAACGGCGGTCCGCGGCCTCTGGTGGACCGGCTGTCGGCA--AGCCGGGTAGCTACGCCGTATCCGA-TAAGGGCTGAAAGCATCCAGGCCCGAAGCGGTCCCCGAA-AATAGGCGGCAGGCC-TCGGGTAAAAGACCCGGTTGATGGGGCGGGGGTGTAAGGGCCTGAGCCCACCGCTCCCAA
Methanosaeta_thermophila_PT                             GGTTGATCCTG-CCAGAGGTTACTGCTATCGGGGTCCGACTAAGCCATGCGAGTTAGCGCACTGCTCAGTAACACGTGGACAACCTGCCCTGAGGACTGGAATAATCC--CGG-GAAACTGGGGGTAATTCCAGATAATGGGTTCTGGCAGAAACGCCTCAGGATGGGTCTGCGGCCTATCAGGGTAGTAGTGGGTGTAACGTACCTACTAGCCTACGACGGGTACGGGTTGTGAGAGCAA-GAGCCCGGAGATGGATTCTGAGACATGAATCCAGGCCCTACGGGGTGCAGCAGGCGCGAAAACTTTACAATGCGGGCAACCGCGATAAGGGGACCTCGAGTGCTGTTGGGCTGCCTAAAAGCAAGGGCCGGGCAAG-ACCGGTGCCAGCCGCCGCGGTAACACCGGCGGCTCGAGTGGTAACCGCTATTATTGGGTCTAAAGGGTCTGTAGCCGGCCGACTAAGTCTCTTGGGAAATCTGGCATCTCAAGTGTCAGGCTGCCAGGGGATACTGGTC-GGCTTGGGACCGGGAGAGGTGAGAGGTACCTCGGG-GGTAGGGGTGAAATCTTGTAATCCTCGAGGGACCACCAGTGGCGAAGGCGTCTCACCAGAACGGATCCGACGGCAAGGGACGAAAGCTAGGGGCACGAACCGGATTAGATACCCGGGTAGTCCTAGCCGTAAACGATACTCGCTAGGTGGTGCCGTAGGGAAGCCGTGAAGCGAGCCACCTGGGAAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAACGGGTGGA-GCCTGCGGTTTAATTGGATTCAACGCCGGAAAGCT-TACCGGGGGCGACAGCAA-TATGAAGGTCGCTGAAGACCTGAGAGGTGGTGCATGGCCGTCGTCAGTTCGTACTGTGAAGCATCCTGTTAAGTCAGGCAACGAGCGAGACCCACGCCCACAGTTGCCAGGCGGGTACTCTGTGGGGACCGCCGCTGC-TAAAGCG-GAGGAAGGAGTGGGCAACGGTAGGTCAGTATGCCCCGAATCCCCCGGGCTACACGCGGGCTACAATGGTCGGTACAATGGGTATCGACCCCGAAAGGGGTAGGCAATCCCCTAAAACCGATCGTAGTTCGGATTGAGGGCTGAAACTCGCCCTCATGAAGCTGGAATCCGTAGTAATCGCGTTTCAAC-AGAACGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCAAACCACCCGAGTAGGCGAATCCGGGCTTTGCAAGGGGGGTTAAGTCGTAACAAGGTAGCCGTAGGGGAATCTGCGGCTGGATCACCTGGATGGCTCGGCTC-GAGCGCTGATGAAGGGCGTGCCAAGCTGCGATAAGCCCCGGCGAGGCGC-AGGGAGCCTTTGAACCGGGGATGCCCTAATGGGACGCCCCGGATTGAAACATCTTAGTAGGGGCAGGAGAAGAAATCAAAACGAGA-TGCCGTCAGTAACGGCGAGTGAACGCGGCA-GAGCCCAAACATCCGAAG-TGGCCTGGAACAAAGAGTGTGATAGCCACGTAGGAGCACTTGAGTACCGTGAGTCG---GATATCTCGCGGGAAGTTGGGGGTCACC-AACCTCCAAGGCTAAATACGTCTCGA-GACCGATAGCGCAGT-AGTAGGGTGACCTAAAGCTGAAAAGAACCCTGGATAGGGGTGTG-AAAAGAGCCTGAAATCGGCTGGCGATCGTGACTTACGTTTTGAAGAACGGACCAAGGAGTGCA-TCTGGCTGGCAA-GGTTAAGTAGCCGAAGCGAAAGCGACATGCGCGCAAGTCAG-CTGGATGCGACCCGAAGCCGGGCGATCTAGGCGTGGGCAGGTTGAAGCGTGG-CGAAAGCTGCGTGGAGGACCG-CTAGCGGTGCTGATATGCAAATCGCTCGCGTGACCTGCGTCTAGGGGTGAAAGTCCAATCGAGCCCGG-AAATAGCTGGTTCCTCCCGAAACATGTCGCAGCATGACCTGGCCGGAGGTAGAG-CACTGATTGGGGCGGG-AAACCGCTCGCTCTCCTGTCAAACTCCCAAGGAAGTCCGGGCTGGT--GGGTAAGCTACTA-GTCCGTGAG-GGAGACAACCCAGACCGT-GGTTAAGGTCCCAAAATGTCGGCT-AAGTGTT-AACACTGAAGGGCGTCCTAGACCTAAGACAACTGGGAGGTTAGCTTAGAAGCAGCTA-CCCTTTAAAGAGTGCGTAACAGCTCACCAGTC----GAGGCCTAGGGCCCCGAAAATGGAC-GGGGCT-AAGCCGACTACCGATACCACGGGTAGGGAG-GCGCCGCG-CGTGGGTGGAAGCA-ACTCCGTGAGGAGTCGTGGAGAAAATCTTGGTAGCAGTA-GCAGCA-AAGTCGGGTGAGAATCCCGACCGCC-GTAAGGGC-CAGGGTTCCTG-GGCAACG-ATCGTCAGCCCAGGGTTAGTCGGTC--CTAAGGTGTGCCA--AATGGGAAACAGGTTAATATTCCTGTACCCGCTTCCGGATAT-GGGAGAGCCGTATGGCGAGAAACGGAC-GAAATTCCGGGAGCCCGTGAAACGTACCGAGAACCAACACTGGTGCCCCGAGCTAAGAA-GGCTCAGGCGTGTCGGAAGTAATCCG-GCTAAGGGAATTCGGCAAATTAGCCACGTAACTTCGGGATAAGTGGTGCCGCAGGTCGCAGTGACGAGGGGGCTCTGACTGTCTAATAACAACATAGGTGGTTGCAGACCCG-AAAGGGCAAGTACAACCACTGAATCCTGCCCAGTGCGGGTACCTGAAAACCCGGTACAAAAGGGCCCGTCAACGGCGGGGGTAACTATGACCCTCTTAAGGTAGCGTAGTACCTTGCCGCTTAATTGGCGGCTCGCATGAATGGATCAACGAGAGCCCCACTGTCCCTAGCCGGAACCCGGTGAACCTTA--CGTCCCAGTGCAGAGTCTGGGGACCCCTGATGGGAAGTGAAGACCCCGTGGAGCTTTACTGCAGCCTGCCGCTGGTTCTGGATGTAGAGCATAGGTAGGAGGCGTCG---AGAGCCACCACTGGAATACTACCCGACACCGGTAGGTGGGCAGTTTGGGTGGGGCGCCACTCCCTAGAAAAGATATCTAGGGAGCCCTAAGGTCGACTCAGTTGGGTCGGAAACCCAACAAAGAGTG-TAAAAGCATAAGTCGGCCTGACGTCATCCCGCATAGCAAAGGATGACGAGACGAAAGTCGGGTTTAGCGAACCTCTCAG---CCCCCTTGGTGGGGGCGTTAGATGACAGA--AAAGCTACCCCGGGGATAACAGAGTCGTCACCGGCAAGAG-CACATATCGACCCGGTGGCTTGCTACCTCGATGTCGGTTCTCTCCATCCTGGCCGTGCAGCAGCGGCCAAGGGTGAGGTTGTTCGCCTATTAAAGGAGATCGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGTTACTATCTGTCAGGGGTGCTTCGCGGTCTGAGGGCAGGCTGGCTTTAGTACGAGAGGAACAAGCCAGCGGCGCCACTGGTCGATCGGTTGTCGGCA-CGGCCGAGCAGCTACGCGCCACAGGGATAAGGGCTGAAAGCATCTAAGCCCGAAACCCAACCCGAA-AAGAGACCGCAGGGC-CCTCGTAAAAGACGAGTTCGATAGAGTCGGGGTGTAAGGTGCTCAGCCCGCGACCACTAA
Methanosarcina_barkeri_str._fusaro                      GGTTGATCCTG-CCAGAGGTTACTGCTATCGGTGTTCGTCTAAGCCATGCGAGTTGGCGTACTGCTCAGTAACACGTGGATAACCTGCCCTTGGGTCCGGCATAACCC--CGG-GAAACTGGGGATAATACCGGATAATGCTTTATGCGTAAAATGCCCAAGGATGGGTCTGCGGCCTATCA-GGTAGTAGTGGGTGTAATGTACCTACTAGCCTACAACGGGTACGGGTTGTGAGAGCAA-GAGCCCGGAGATGGATTCTGAGACATGAATCCAGGCCCTACGGGGCGCAGCAGGCGCGAAAACTTTACAATGCGGGAAACCGTGATAAGGGGACACCGAGTGCTGTCCAGGTGTGTAAAAGCAAGGGCCGGGCAAG-ACCGGTGCCAGCCGCCGCGGTAACACCGGCGGCCCGAGTGGTGATCGTGATTATTGGGTCTAAAGGGTCCGTAGCCGGTTTGGTCAGTCCTCCGGGAAATCTGATAGCTCAACTATTAGGCTTTCGGGGGATACTGCCA-GACTTGGAACCGGGAGAGGTAAGAGGTACTACAGG-GGTAGGAGTGAAATCTTGTAATCCCTGTGGGACCACCTGTGGCGAAGGCGTCTTACCAGAACGGGTTCGACGGTGAGGGACGAAAGCTGGGGGCACGAACCGGATTAGATACCCGGGTAGTCCCAGCCGTAAACGATGCTCGCTAGGTGGTGCCGCAGGGAAGCCGTGAAGCGAGCCACCTGGGAAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACAACAACGGGTGGA-GCCTGCGGTTTAATTGGACTCAACGCCGGACAACT-CACCGGGAACGACAGCAA-TATGTAGGTCGCCGAAGACCTGAGAGGAGGTGCATGGCCGTCGCCAGTTCGTACTGTGAAGCATCCTGTTAAGTCAGGCAACGAGCGAGACCCGTGCCCACTGTTACCAGATGGGTACTCTGTGGGGACCGCCGGTGT-TAAATCG-GAGGAAGGTGCGGGCCACGGTAGGTCAGTATGCCCCGAATTTCCCGGGCTACACGCGGGCTACAATGAATGGGACAATGGGTCCCTCCCCTGAAAAGGGCTGGTAATCTCACAAACCCATCCTTAGTTCGGATCGAGGGCTGTAACTCGCCCTCGTGAAGCTGGAATCCGTAGTAATCGCGTTTCAAT-ATAGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCAAACCACCCGAGTGAGCGAACCTGTGCTTTGCAAGGGGGGTTAAGTCGTAACAAGGTAGCCGTAGGGGAATCTGCGGCTGGATCACCTGGATGGCTCGGCTC-AAGAGCTGATGAAGGACGTGCCAAGCTGCGATAAGCCCGGGGTAGGTGC-AAGGAGCCTATGAACCCGGGATTTCCGAATGGGACGCTCCGAATTGAAACATCTCAGTAGGAGCAGGAAAAGAAATCAACC-GAGA-TACCGTGAGTAACGGCGAGTGAAAACGGCA-CAGTTCAAACAACAGAAC-TTGCCTGAAACGTAGAGTGTGACAGTCACGTATGTGTACCTGAGTACCGTGCGTTG---GATATCGTGCGGGAATCTGGGGGGCACC-AACCTCCAAAACTAAATACTACTTGA-GACCGATAGCGAAAT-AGTAGGGTGACCGAACGCTGAAAAGTACCCCGAGAAGGGAGGTG-CAAAGTGCCTGAAACCTGATAGTGATCGTATCTTACGTTTTGAAGAACGGGCCAGGGAGTTTA-TCTCAGTGGCAATGGCTAAGCAGCCGAAGCGAAAGCAACATGTGCGCAAGTCAC-TGGGGTAAGACCCGAAGCCGGGTGATCTAGGCGTGGGCAGGTTGAAGCGTGG-CGAAAGCTACGTGGAGGACCG-CAAGCGGTATTGATCTGCAAATCATTCGTGTGACCTGCGTCTCGTAGTGAAATGCTAATCTAACCCGG-CATCCGCTGGTTCCTTCCAAAACATGTCGCAGCATGACCTGACTGGAGGTAGAG-CACTGATTGGGGGGGG-AAACTCCTCGCTCGCCTGTCAAACTCCAAAGG-AGTCCGGACTGCT-GGGGTAAGCTTGTA-GTCCGTAAG-GGAGACAACCCATCCCGT-GGTTAAGGTCCCCAAGTGTCGACT-AAGTGTT-AATACTAAAGGGCGTCCCAAGCCCAAGACAGCTGGAAGGTTAGCTTAGAAGCAGCTA-CCCTTTAAAGAGTGCGTAACAGCTCACCAGTC----GAGGTTTGGGGCCCCGAAAATTGAC-GGGGCTCAAGTCGACCACCGATACCACGGGTAGGAAG-GCGTTGCG-TTCGGGCCGAAGCA-GGGCTGTAAAGTCCTGTGGAGAAAATCCTGGTAATAGTA-GCAGCA-AAGCAGGGTGAGAATCCCTGCCGCC-GAAGGGGC-CAGGTTTCCTC-GGCAATG-ATCGTCAGCCGAGGGTTAGTCGGTC--CTAAGACGTACCG--AAAGGGAAACAGGTTAATATTCCTGTACCCGTCTCTGGGCAG-AGGAGAGCCGTATGGCGAGAATCGGGC-GAACACCCCGGGACCCGTGAAACGTACCAAGATCTGACACTGGTGCCCCTAGCTGAAAA-GGCTAAGGCGTGTCGGAGT-ACTTCA-GTTAAGGGAATTCGGCAAATTAGCTCCGTAACTTCGGGATAAGGAGTGCCGCAGGTCGCAGTGACCAGGGGGCTCTAACTGTCTAATACCAACATAGGAGATTGCAAACCCG-TAAGGGCTAGTACAATCTCTGAATCCTGCTCAGTGCAGGTACCTGAAACCCCGTTTCAAAAGGGCCTGTAAACAGCGGGGGTAACTATGACCCTCTTAAGGTAGCGTAGTACCTTGTCGCTTAATTGGCGACTTGCATGAATGGATCAATGAGAGCCCTACTGTCCCTAACTGGAATCCGGTGAAGCTTA--CATTCTAGTGCACAGTCTAGAGACCTCTAGGGGGAAGTGAAGACCCCGTGGAGCTTTACTGCAGCCTGTCGCTGGTTCTGGATGTACAGAGTAGGTAGGAGGCATCG---AGAGCCGCAATTGGGACACTACCCGACCCCGATAGGTGGGCAGTTTGCCTGGGGCGGGACGCCCTTGAAAAGATATCAAGGGCGCGCAATGGTTGACTCAAGCGGGTCGGAAACTCGCTGAAGAGTG-CAAGAGCATAAGTCAGCCTGACGTTATTCAGCATAGCAGTGGATGACGAGACGAAAGTCGGCTCTAGCGAACTTTTGAG---CCTCCTTGGTGGGGGCCAAAAATGACAGA--AAAGTTACCCCGGGGATAATTGAGTCGTTGCCGGCAAGAG-TACATATCGACCCGGCAGCTTGCTACCTCGATGTCGGTTCTTTCCATCCTGGCCGTGCAGCAGCGGCCAAGGGTGAGGTTGTTCGCCTATTAAAGGAGATCGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGTTACTATCTACTAGAGGTGCA-CGAGGTCTGCGGGTAAGCTGCTTTTAGTACGAGAGGAACCAAGCAGCGGCGCCACTGGTGTACCGGTTGTCGGCA-TAGCCGGGCAGCTACGCGCCAAAGAA-TAAGAGCTGAATGCATCTAAGCTCGAACTCTCACCTAAA-AAGAGACCTCAGGAT-TCCGGTAGAAGACCGGTTTGATAGAAACGGGATGTAAGGTGTTCAGTCCGCGTTTACTAA
'Methanospirillum hungatei JF-1'                        GGTTGATCCTG-CCAGAGGCCACTGCTATCGGGGTTTGACTAAGCCATGCGAGTCGGCGTACTGCTCAGTAACACGTGGACAATCTGCCCTGAAGAGGAGGATAATCC--CGG-GAAACTGGGGGTAATACTCCATAATGTTATGCGAACGAAACGCTTCAGGATGAGTCTGCGGCCGATTA-GGTAGTTGTTGGGGTAACGGCCCAACAAGCCTGTCATCGGTACGGGTTGTGGGAGCAA-GAGCCCGGAGATGGATTCTGAGACACGAATCCAGGCCCTACGGGGCGCAGCAGGCGCGAAAACTTTACCATGCGGGCAACCGTGATAAGGAAACCCCGAGTGCTGTCCACCAGTGTAAAAGAAAGGGCCGGGCAAG-ACCGGTGCCAGCCGCCGCGGTAATACCGGCGGCTCGAGTGGTGGCCGCTATTACTGGGCTTAAAGGGTCCGTAGCTGGATATACAAGTCCCTTGAGAAATCCGCCGGCTTAACCGGTGGGCGTTCAGGGGAAACTGTAT-TTCTAGGGACCGGGAGAGGTGAGAGGTACTGCCGG-GGTAGGAGTGAAATCCTGTAATCCCGGTGGGACCACCTATGGCGAAGGCATCTCACCAGAACGGGTCCGACAGTGAGGGACGAAAGCTGGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCCAGCTGTAAACGATGCGCGTTAGGTGGTGCCGAAGGGAAACCGTGAAACGCGCCGCCTGGGGAGTACGGTCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAACGGGTGGA-GCCTGCGGTTTAATCGGACTCAACGCCGGAAATCT-CACCGGATAAGACAGCTG-AATGATAGTCGATGAAGACTCGAGAGGAGGTGCATGGCCGTCGTCAGTTCGTACTGTGAAGCATCCTGTTTAGTCAGGCAACGAGCGAGACCCACGCGAGCAGTTGCCAGATGGGGACACTGCTCGGACCGCCTCTGC-TAAAGGG-GAGGAAGGAATGGGCAACGGTAGGTCAGCATGCCCCGAATTATCCGGGCTACACGCGGGCTACAATGGACAGGACAATGGGTTTCGACACCGAGAGGTGAGGATAATCTCCTAAACCTGTCCGAAGTTCGGATTGCGGGTTGTAACTCACCCGCATGAAGCTGGAATCCGTAGTAATCGCGTTTCAAC-ATAGCGCGGTGAATATGTCCCTGCTCCTTGCACACACCGCCCGTCAAACCACCCGAGTGAGCGAATCTGGGTTTTGCAAGGGGGGTTAAGTCGTAACAAGGTAGCCGTAGGGGAATCTGCGGCTGGATCACCTGGATGGCTCGGTTC-GGGTGCCGACGAAGGGCGTGCCAAGCTGCGATAAGCTCCGGGTAGACGC-ATGGAGTCATTGAACCGGAGATCCCCGAATAGGACGCCCCGAATTGAAACATCTTAGTAGGGGCAGGAGAAGAAACCAACC-GGGA-TGTCGTTAGTAGAGGCGATCGAACACGACA-GAGTTCAAACAACTGAAG-TTGCCTGGAACAGAGAGGGTGACAGTCCCGTATGTGTACCTGAGTAGCGTGGGTCG---GAATTCCCGCGTGAATGTGGGGGTCATC-AACCTCCAAAACTAAATACTCCCCGA-AACCGATAGCGTAGT-AGTAGCGTGAGCGAAAGCTGAAAAGCAACCCTGGAAAGGTGTTG-AAAAGTGCCTGAAACTGACAGGTTATCGTATCGTACGTTTTGAAGAACGGGCCAGAGAGTTTA-TTCTGTTGGCGACGGTTAAGAAGCCAGAGGGAAACCAACAAGTCCGCAAGTCAG-CAGGATAAGACCCGAATCCCGGCGATCTATGCGTGGGCAGGTTGAAGCGTGC-CGAAAGGTGCGTGGAGGACCG-CAAGCGGTTTTGATATGCAAATCATTCGCGTGACCTGCGTATAGGAGTGAAAGATTAATCGAGCCGGG-CATCAGCTGGTTCCTCTCGAAACATGCCGTAGCATGACCTGATCTGAGGTAGAG-CACTGATTGGGGGAAG-AAATTCCTCACTCTCCTGTCAAACTCCAAAGGAAGTCCGCATTAC--GGGGTAAGCTTGTA-ATGCGTAAG-GGAGACAACCCAGACCGT-GGTTAATGTCCCTCAGTGCAGGCT-CAGTGTA-AACACTGAAAGTAGTCCTGGGTCAAAGACAACTGGGAGGTGAGCTTAGAAGCAGCTA-CCCTTTAAAAAGTGCGTAACAGCTTACCAGTC----AAGATTCAGGGCGCTGAAAATGGAC-GGGGCTTAAGCCTGCCACAGATACCACGGGTAGAGAG-GCGTCCTG-CATGGGCGGAAGCA-GGGTTGCAAGATCCTGTGGAGAAAATTCTGGCAGTAGTA-GAAGCTTAAGATTGGTGAGAATCCAATCCGCC-GCAGGGGC-TAGGTTTCCTC-GACAATG-TTCGTCAGTCGAGGGTTAGTCGGTC--CTAAGACGTACCG--AAAGGGAAACAGGTTAATATTCCTGTACCCGCTTTCGGATAG-GGGAGTACCGTATGGTGAGAATTTTTC-AAAATTCCAGGAGCCCGTGAAACGTACCGAGAACTGACACAGGTGCCCCTCGCTGAGAA-GGCGAAGGCGTGTCGGGAGTAAATGT-GTTAAGGGAACTCGGCAAATTAGCCCTGTAACTTTGGGATAAGGGGTGCCGCAGGTCGCAGTGACAAGATCGCTCCGACTGTCTAATAACAACATAGCAGACTGCAACTCCG-AAAGGACTCGTATAGTCTGTGATTCCTGCCCAGTGCGAGTATCTGAACACCGGGTTCAAAAGGACTCGTAAACGGCGGGGGTAACTATGACCCTCTTAAGGTAGCGTAGTACCTTGTCGCTTAATTGGCGACTTGCATGAATGGAATAACGAGAGCGATACTGTCCCTAACACATACCCGTTGAACCTTT--TGTACTAGTGCAGAGACTAGTGACTCCTTATGGGAAGTGAAGACCCCGTGGAGCTTTACTGCAGCCTGTCGTTGGTATTACCTGCGCAGGGTAGATGGGAGACGTCG---ATAGTCACCGATGAGACACCATCCGACATCGATAGGTAGGCAGTTTGGGTGGGGCGCCACACCCTCGAAAAAATATCAAGGGTGCCCTAAGGTCAACTCAAGCGGGTCAGAAACCCGCTGAAGAGTGTCAAGAGCAAAAGTTGGCCTGACGCGATTTCGCATAGCAAGAAATCGCGAGAGGAAACTCGGGTCTAACGAACCAATACG---CCCTGTTGATGAGGGCTATTGACTACAGA--AAAGCTACCCCGGGGATAACAGAGTCGTCGCCGGCAAGAG-CACATATCGACCCGGCGGCTTGCTACCTCGATGTCGGTTCTTTCCATCCTGGCTGTGCAGCAGCAGCCAAGGGTGAGGTTGTTCGCCTATTAAAGGGGATCGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGTTACTATCTATAAGGAGTGTT-GGAAGTCTGAAGGCAAGAATGAAATAGTACGAGAGGAACTTTCATTCGGCGCCACTGGTCTACCGGTTGTCGGCA-ACGCCGGGCAGCTACGCGCCAAGAGA-TAAAAGCTGAAAGCATCTAAGCTTGAAACTCAGCCTGAACAAGAGACTTCAAGAC-ACGGGTAAAAGACCCGGTTGATAGGTTCGGGATGTAACGTGTTCAGTCCGCGAATACTAA
Methanothermobacter_thermautotrophicus_str._delta_H     GTTTGATCCTG-GCGGAGGCTACTGCTATTGGGGTTCGATTAAGCCATGCAAGTCGGCGAACGGCTCAGTAACACGTGGATAACCTGCCCTTGGGACTGGGATAACCC--CGG-GAAACTGGGGATAAACCTGGATAATGGTGCTTCACCGAAATGCCCAAGGATGGGTCTGCGGCCGATTA-GGTAGTTGGTAGGGTAACGGCCTACCAAGCCCATCATCGGTACGGGTTGTGAGAGCAA-GAGCCCGGAGATGGAACCTGAGACAAGGTTCCAGGCCCTACGGGGCGCAGCAGGCGCGAAACCTCCGCAATGCACGCAAGTGCGACGGGGGAACCCCAAGTGCTTTTCAGAAGTGTAAAAATAAGGGCTGGGCAAG-ACCGGTGCCAGCCGCCGCGGTAACACCGGCAGCTCAAGTGGTAGCCGCTTTTATTGGGCCTAAAGCGTCCGTAGCCGGTCTGATAAGTCTCTGGTGAAATCCCGCAGCTTAACTGTGGGAATTGCTGGAGATACTATCATGACTCGAGGTCGGGAGAGGCTGGAGGTACTCCCAG-GGTAGGGGTGAAATCCTGTAATCCTGGGAGGACCACCTGTGGCGAAGGCGTCCAGCTGGAACGAACCTGACGGTGAGGGACGAAAGCTAGGGGCGCGAACCGGATTAGATACCCGGGTAGTCCTGGCCGTAAACGATGTGGACTTGGTGGTGCCGAAGGGAAGCTGTTAAGTCCACCGCCTGGGAAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAACGCGTGGA-GCCTGCGGTTTAATTGGATTCAACGCCGGACATCT-CACCAGGGGCGACAGCAG-TATGATGGCCGTTGATGACCTGAGAGGAGGTGCATGGCCGCCGTCAGCTCGTACCGTGAGGCGTCCTGTTAAGTCAGGCAACGAGCGAGACCCACGCCCTTAGTTACCAGCCGGGCACACTAAGGGGACCGCCAGTGA-TAAACTG-GAGGAAGGAGTGGACGACGGTAGGTCCGTATGCCCCGAATCCCCTGGGCAACACGCGGGCTACAATGGCCTGGACAATGGGTTCCGACACTGAAAGGTGGAGGTAATCCCCTAAACCAGGTCGTAGTTCGGATCGAGGGCTGTAACTCGCCCTCGTGAAGCTGGAATGCGTAGTAATCGCGTGTCATT-ATCGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCACGCCACCCAAAAAGGCGAATCTGGGTTCTTTGAGGAGGGCGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGGCTTGGCTTGAGTCGCTGATGAAGGCCGTGGCAAGCTGCGATAAGCCCAGGGGAGGAGC-ATGCATCCTTGGATCCTGGGATTGCCGAATGGGACCCGCCGAACTGAAACATCTTAGTAGGCGGAGGAAGAGAAAGCAAATTGCGACTGCCGTGAGTAATGGCGAATGAAAGCGGTG-CAGGACAAACTGTTGAACTTGGGCTGGAACGTAGAGGGTTAAAGCCCCGTAGATGCCCCTGAGTAGCGTCCATTG---GATATTGGGCGTGAAGCTGGGAGGCATC-GACTCCTAATCCTAAACACGTCTCAA-GTCCGATAGCGAACT-AGTACCGTGAGGGAAAGCTGAAAAGTACCCCTGATAGGGGTGTG-AAAAGTGCCTGAAACCAGGCGGTGATCGTGTCGTCCGTCTTGAAACACGGGCCAGGGAGTTTAGTGGTTGTGGCGA-GGCTAAGTAGTCGTAGGGAAACCGACAGGTCCGCAAGTCAC-AGCTCTAAAACCCGAAGCCGGTCGATCTAGCCCTGGGTAGGGTGAAGTCGCT-CTTACGAGTGATGGAGGCCCG--CAGGGGTGTTGTCGTGCGAAACATTCCTCTAACCTGGGGTTAGTGGTGAAAGGCCAATCAAGGCCGG-TGACAGCTGGTTCCACCCGAAATGGCTCGTAGGCCAGCCTGACTGGAGGTAGAG-CACTTATTGGGGGGAG-AGATCCCTCGGCATCCTGTAAAACTCCGAAGG-AGTCAGGGGCGC--GGGGTAAGCCTGTG-TCCCGAGAG-AGGAACAACTCAGACTGG-GGTTAAGGTCCCTAAATGCCGGCT-AAGTCTA---------AGGGGGTCTTTGGCCCTAGACAATGGGAAGGTGGGCTTAGAAGCAGCCA-TCCTTTAAAGAGTTCGTAACAGATCACCCATC----GAGGTCAAAGGCACCGAAAATGGAG-GGGAATTAAGCCGGCTACCGATACCTCAGGTAGGGTG-GCGTCCGG-TTGGGGTTGAAGTG-GGGGCGTGAGCTCCTGTGGAGAGGATCCTGGTAGTAGTA-GCAGCG-AAGTGAGGTGTGAATCCTTACCGCC-GGAGGGGC-TAGGGTTCCTT-GGCAATG-TTCGTCAGCCAAGGGTTAGTCGGTC--CTAAGGCCGTGGG--AAAGGGTAACGGGTTAATATTCCTGTACGCGCTTTGGGGTAG-GGGAGAGCCGTATGGCGAGAACCATGGTGAATGCCCTGGAGTCCTTGAAACGTACCGAGATCCGACACTGGTGCCCCTAGCTGAGTA-GGCTAAGGTGTGTTGGGGT-AACCTG-GCTAAGGGAAATCGGCAAATTGGCCCCGTAACTTTGGGAGAAGGGGTGCCGCTGGTCGCAGTGACAGGGGGGGCCCGACTGTTTAATAAAAACATAGCTCCTAGCTAGCCCG-TGAGGGTGTGTACTGGGGGCGACACCTGCCCAGTGCCGGCACGTGAAGCCCTGGTTCAAAAGCGCCGGTAAACGGCGGGGGTAACTATAACCCTCTTAAGGTAGCGAAATGCCTTGCCGGATAAGTACCGGCCTGCATGAATGGTTGAACGAGGTCCCTACTGTCCCTAGCCAGGACCTAGTGAAGCTGC--TGTTCTGGTGCACAAGCCAGAGACTCCCAGTGGGAAGCGAAGACCCCGTAGAGCTTTACTGCAGTCTGCTGTTGGTCATGGGTATGCAGTGTAGGTGGGAGGCGTCG---AGAGTCGGTCATGAGACACCACCTGACATCGGTAGATGGGCAGTTTGGCTGGGGCGGCACGCGCTTGAAATGGTATCAAGCGCGCCCTAAGGTCGGCTCAGGCGGGACAGAGATCCGCTGTAGAGTG-TAAGGGCATAAGCCGGCTTGACTGTGCTCCTACTAGTAGGGGGTGCAGGTGCGAGAGCAGGGCCTAGCGAACCCCAGAGT--CCTCGTCGGTGGGGGCCTGGGATGACAGA--AAAGCTACCTCGGGGATAACTGGGTGGTCGCAGGCAAGAG-CCCATATCGACCCTGCGGCTTGCTACTTCGATGTCGGTTCTTTCCATCCTGGGTGTGCAGCAGCACCCAAGGGTGGGGTTGTTCGCCCATTAAAGGGGAACGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTTGGTTGCTATCTACTGGGAGTGTGTGGTTGCCTGAGGGGAAGGTGGTTCCAGTACGAGAGGAACGGACCGTCGGCGCCTCTGGTTTACCGGTTATCGGTA-TTGCCGGGCGGCTACGCGCTATGATTATAAAGGCTGAAGGCATCTAAGCCTGAGGTTTTCCCTGAA-AATAGGTGGCTGGACTGCGGGTAGAAGACCTGTTTGTTGGGGCGGGGGTGTGAGTTGTTTAGCCTGCCGTTTCCAA
Mycobacterium_tuberculosis                              GTTTGATCCTGGCTCAGGACGAACGCTGGCGGCGTGC--TTAACACATGCAAGTCGGCGAACGGGTGAGTAACACGTGGGTGATCTGCCCTGCACTTCGGGATAAGCC--TGG-GAAACTGGGTCTAATACCGGATAATGTCTTGTGGTGGAAACGGTGTGGGATGAGCCCGCGGCCTATCA-GCTTGTTGGTGGGGTGACGGCCTACCAAGGCGACGACGGGTAGCCGGCCTGAGAGGGT-GTCCGGCCACACTGGGACTGAGATACGGCCCAGACTCCTACGGGAGGCAGCAGTGGGGAATATTGCACAATGGGCGCAAGCCTGATGCAGCGACGCCGCGTGCCTCTTTC-ACCATCGAAAGAAGCACCGGCCAAC--TACGTGCCAGCAGCCGCGGTAATACGTAGGGTGCGAGCGTTGTCCGGAATTACTGGGCGTAAAGAGCTCGTAGGTGGTTTGTCGCGTTGTTCGTGAAATCTCACGGCTTAACTGTGAGCGTGCG-GGCGATACGGGCA-GACTAGAGTACTGCAGGGGAGACTGGAATTCCTGG-TGTAGCGGTGGAATGCGCAGATATCAGGAGGAACACCGGTGGCGAAGGCGGGTCTCTGGGCAGTAACTGACGCTGAGGAGCGAAAGCGTGGGGAGCGAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGGTGGGTACTAGGTGGTGCCGTAGCTAACGCATTAAGTACCCCGCCTGGGGAGTACGGCCGCAAGGCTAAAACTCAAAGGAATTGACGGGGGCCCGC-ACAAGCGGCGGA-GCATGTGGATTAATTCGATGCAACGCGAAGAACCT-TACCTGGGTTTGACATGCACA-GGA-CGCGATAGG--CGTTGCAGGTGGTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTCTCATGTTGCCAGGTGGGGACTCGTGAGAGACTGCCGGGGT-CAACTCG-GAGGAAGGTGGGGATGACGTCAAGTCATCATGCCCCTTATGTCCAGGGCTTCACACATGCTACAATGGCCGGTACAAAGGGCTGCGATGCCGCGAGGTTAAGCGAATCCTTAAAAGCCGGTCTCAGTTCGGATCGGGGTCTGCAACTCGACCCCGTGAAGTCGGAGTCGCTAGTAATCGCAGATCAGCAACGCTGCGGTGAATACGTTCCCGGGCCTTGTACACACCGCCCGTCACGTCATGAAAGTCGGCGAAGGTGGGATCGGCGATTGGGACGAAGTCGTAACAAGGTAGCCGTACCGGAAGGTGCGGCTGGATCACCTGGATGCCTTGGCATCGAGAGCCGATGAAGGACGTGGGAGGCTGCGATATGCCTCGGGGAGCTGTCAACCGAGCGTGGATCCGAGGATTTCCGAATGGGACGCGGGGAAGTGAAACATCTCAGTACCCGTAGGAGGAGAAAACAATT-GTGA-TTCCGCAAGTAGTGGCGAGCGAACGCGGAA-CAGGCTAAACAGCGGAAG-TGGCCTGGGACGTAGACGGTGAGAGCCCGGTACGCGAACCCGAGTAGCAGCGGGCCCGTGGAATCCGCTGTGAATCCGCCGGG-ACC-ACCCGGTAAGCCTAAATACTCCTCGATGACCGATAGCGGATT-AGTACCGTGAGGGAATGGTGAAAAGTACCCCGGG-AGGGGAGTGAAAGAGTACCTGAAACCGTGTGCCTATGATGGCGTGCCTTTTGAAGAATGAGCCTGCGAGTCAGGGACATGTCGCAA-GGTTAAGTAGCCGCAGCGAAAGCGAG-TCTGAATAAGTGGCGTGTTCTG-GACCCGAAGCGGAGTGATCTACCCATGGCCAGGGTGAAGCGCGG-GTAAGACCGCGTGGAGGCCCG---AACCCACTTAGGTTGAAGACTGAGGGGATGAGCTGTGGGTAGGGGTGAAAGGCCAATCAAACTCCG-TGATAGCTGGTTCTCCCCGAAATGCATTTAGGTGCAGCGTTGCG-TGGGTAGAGCTACTGGATGGGCCCT-ACTAGGTTACTGACGTCAGCCAAACTCCGAAGGCAGTGAGACGGCGG-GGGATAAGCTCCGTACGTCGAAAG-GGAAACAGCCCAGATCGCCGGCTAAGGCCCCCAAGCGTGTGCT-AAGTG-------GGAAAGGATGTGCAGTCGCAAAGACAACCAGGAGGTTGGCTTAGAAGCAGCCA-CCCTTGAAAGAGTGCGTAATAGCTCACTGGTC----AAGTGATTGTGCGCCGATAATGTAGCGGGGCTCAAGCACACCGCCGAAGCCGCGGGTAGGGGA-GCGTCCCT-CATTCAGCGAAGCCAC-CGGGTGACCGGTGGTGGAGAGAATGCAGGCATGAGTA-GCGACA--AGGCAAGTGAGAACCTTGCCCGCC-GAAAGACC-AAGGGTTCCTG-GGCCAGG-CCAGTCCGCCCAGGGTGAGTCGGGA-CCTAAGGCGAGGCGTCGATGGACAACGGGTTGATATTCCCGTACCCGCAGGAAGGTAG-CGCAAATCCGTCTAATCCTGAGAGGT--GACATCCTCTGCTGCCAAGAAACGTACCCCAAACCGACACAGGTGGTCAGGTA-GAGCA-TACCAAGGCGT-ACGAGATAACTATG--GTTAAGGAACTCGGCAAAATGCCCCCGTAACTTCGGGAGAAGGGGGACCTCCGGTCGCAGAAACCAGTGAGGAGCGACTGTTTACTAAAAACACAGGTCCGTGCGAAGTCG-CAAGACGATGTATACGGACTGACGCCTGCCCGGTGCTGGAAGGTTAAGAGGACCCGTTAAAGCCCCAGTAAACGGCGGTGGTAACTATAACCATCCTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCTGCACGAATGGCGTAACGACTTCTCAACTGTCTCAACCATAGACTCGGCGAAATTGC--ACTACGAGTAAAGATGCTCGTTACGCGCGGCAGGACGAAAAGACCCCG-GGACCTTCACTACAACTTGGTATTGGTACGGTTTGTGTAGGATAGGTGGGAGACTGTG---AGAGTCGTTGTTGAAATACCACTCGACAGTGCCTGGCGGGTAGTTTAACTGGGGCGGT-TGCCTCCTAAAATGTAACGGAGGCGCCCAAAGGTTCCCTCAACCTGGACGGCAATCAGGTGGCGAGTG-TAAATGCACAAGGGAGCTTGACTGCGAGACTTA---CAAGTCAAGCAGGGACGAAAGTCGGGATTAGTGATCCGGCACCC---CCGAGTGGAAGGGGTGTCGCTCAACGGATAAAAGGTACCCCGGGGATAACAGGCTGATCTTCCCCAAGAG-TCCATATCGACGGGATGGTTTGGCACCTCGATGTCGGCTCGTCGCATCCTGGGGCTGGAGCAGGTCCCAAGGGTTGGGCTGTTCGCCCATTAAAGCGGCACGCGAGCTGGGTTTAGAACGTCGTGAGACAGTTCGGTCTCTATCCGCCGCGCGCGTC-AGAAACTTGAGGAAA-CCTGTCCCTAGTACGAGAGGACCGGGACGGACGAACCTCTGGTGCACCAGTTGTCGGCAC-CGCTGGATAGCCACGTTCGGTCAGGATAACCGCTGAAAGCATCTAAGCGGGAAACCTTCTCCAAG-ATCAGGTTTCAAGGCCCCCCGCAGAACACGGGTTCAATAGGTCAGACCTGGAATGGGTGTAGGGAACTGGTGCTAA
Nanoarchaeum_equitans                                   CGTTGATCCTG-CGGGAGGCCACCGCTATCTCCGTCCGGCTAACCCATGGAAGGCGCCGCACGGCTGAGTAACACGTCGGTAACCTACCCTCGGGACGGGGATAACCC--CGG-GAAACTGGGGCTAATCCCCGATAAGGCCCCATCCCCGAGACGCCCGAGGATGGGCCGGCGGCCCATCA-GGTAGTTGGCGGGGTAATGGCCCGCCAAGCCGAAGACGGGTAGGGGCCGTGAGAGCGG-GAGCCCCCAGATCGGCACTGAGACAAGGGCCGAGGCCCTACGGGGCGCACCAGGGGCGAAACCTCCGCAATGCGGGAAACCGTGACGGGGGGACGGAGAGTGCTTTTGGGGAGTGTAAGAATAAGCGGTGGGCAAG-AGGGGTGGCAGCCGCCGCGGGAACACCCCCACCGCGAGCGGTGGCCGTGATTATTGGGCCTAAAGGGGCCGTAGCCGGGCCGGTGTGGCTCCGGTGAAATCCTCGGGCTCAACCCGAGGGCGCGCCGGAGCTACTACCG-GCCTAGGGACCGGGAGGGGCCGACCGTACTCCCGG-GGGAGCGGTGAAATGCTGTAATCCCGGGAGGACGACCCGTGGCGAAAGCGGTCGGCCAGAACGGGTCCGACGGTGAGGGCCGAAGGCCGGGGGCTAGAACGGGATTAGAGACCCCGGTATTCCCGGCTGTCAACGCTGCGGGCTACCTGGTGGGGTAGGGAAGCCGTTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATAGGCGGGGGAGCAC-ACAAGAGGTGGG-GTGCGCGGTTTAATTGGATTCGACGCCGGGAACCT-CACCGGGGCTGACAGCAC-AATGATGGTCCCTGAAGGGCCGAGAGGAGGTGCATGGCCGCCGTCAGCCTGTGCCGTGAGGTGCCCTGTTAAGTCAGGAAACAGGCGAGACCCGCGCCCGCAGTTGCGAGGCCGGCACACTGCGGGGACTGCCGGGG--AAACCCG-GAGGAAGGTGCGGGCGACGGCAGGTATGCATGCCCCGAATGCCCCGGGCTACACGCGCGCATCAATGGGCGGGACAGGGGGCCGCGACCCCGAAAGGGGGAGCAAATCCCC-AAACCCGCTCTCAGTCCAGATCGAGGGCTGCAACTCGCCCTCGTGACGGCGGAATCTCTAGTAGTCGGACGTCACC-AGCGTCCGGCGAATACGTCCCTGCTCCTTGCACTCACCGCCCGTCAAGCCACCCGAGCTGGCGAGCTAGGCCCCGGCGAGGGGGGCTAAGTCGACACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGCCTGGGCTC-GGGAGCCGAAGAAGGGCGTGGCAAGCTGCGATAAGCCAGGGGGAGGCGC-ACGCAGCCGTTGATCCCTGGATCCCCGAATGGGACGCGGGGAAGTGAAACATCTCAGTACCCGCAGGAAAAGAAAGAGAAATTCGA-TGGCGGGAGTAGGGGCGACCGAAACCGCCG-TAGCCCAAACACCCGAAC-TCCGGTGGAACGTAGAGGGTGACAGCCCCGTAGGGGTACCAGAGTACCGCGCCTCG---GATATGGCGCGGGAAGCTGGGGGACACA-CGCCCCCAAGGCTAAATACTCCCCGA-GTCCGATAGCGGACT-AGTAGGGTGACCGAAAGGTGAAAGAGAACCCGTGGAAGGGAGTGAAAAAGAGCCTGAAACCGGGCGGGGATTCCACCGTACGTTCGGGAGCACGTGCGGGGGAGTGTG-CCCGAGTGGCGA-GGTTAAGAAGCCGTAGGGAAACCGAA-GGCCCGCAAGTCAC-TCGGGCACGACCAGAAGCCCGGCGATCTACCCCGGGGCAGGGTGAAGCGGGG--TTTTTCCCCGTGGAGGCCCG--AAGGGGTGGTGGCCT---ATCCCCTCCTCTGACCCCGGGGTAGGGGCGATATACCAATCGAGCCGGG-TGATAGCTGGTTCCCGCCGAAATGGGCTGCAGTCCAGCCTCGGCGGAGGTAGAGCGACGGATTCCGGGGTT-AACCCCACCACGGG--AGTCCAACTCCGAAGG-AGACGGGGGCGGC--GGATAAGCCGCCG-TTCCGAGAC-GGGAACAACCGAGACCGG-GGTTAAGGCCCCTAAGTGCCGGCT-AAGTGGC-----TGGAAGGGTGTCCGCTCCCTAAGACACCGGGGATGTGGGACTAGTAGTGTCCA-TCATCTAAGGAGTGTGCAACAACTCACCCGGC----GAGGGAGCGGGCCCCGCAGATGGAC--GGGCCTAAGCCGGCCGCCGAGACCCCGGGTAGGCGG-GCGTCCCG-GTGGCCTAGAAGGC-GGGCCGTGAGGTCCGCTGGAGAGAATCCCCGCGTGAGTA-GGAGCA-AAGAGGGGTGAGAAGCCCCTCCGCC-GAAAGGGAAAAGGGTTCCCT-GGCAATG-ACCATCAGCCAGGGGTGAGTCGGTC--CTAAGGCCGGCGG--AAAGGGAAAGGGGTTAATATTCCCCTACCCGCCTGGGGCTAG-GGGAGTGCCATATGGCGAGAACCGGCCTAAAAGGCCCTGGGCCCATGAAACGTACCGAGAACCGTGACAGGTTCCC-TGGGTGAGCA-GCCTAAGGCG-GTGGGGTATAACCTG-GCCGAGGGAAATCGGCAAATTGGCCCCGTATCTTCGGTAGAAGGGGTGCCGCAGGTCGCAGTGACAAGGGCGGGCCGACTGTTTACTAAAAACATAGCCTCCGGCAAGCCCG-AAAGGGTGTGTACCGGAGGTGACGCCTGCCCAGTGCCGGTACCTGAACCCCCCGTCCAAAAGGGCCGGTAAACGGCGGGAGTAACTGTAACTCTCTTAAGGTAGCGTAGTCCCTTGCCGGTTAAATGCCGGCTC-TGCGAACGGCGTAACGAGCTCGCCACTGTCCTCGGCCAGGGCCCCCTGAAAACGC--CGTTCCCGTGGATAGGCGGGAGAGGCCCGGTGGGAAGAGAAGACCCCGTGAAGCTTAACCGCAGCCTGTCGTTGGTCCCCCACGCTCAGCGTAGCGGGGAG-CGATG---AGATGCGCCCATGAGACACCCGCCGACAGCGGCAGGTGGGCGGTTTGGCTGGGGCGGCACACCGCCGAAAAGATATCGGCGGTGCCCAAAGGTCGGCTCAGGCGGGTCAGAAATCCGCCGTAGAGTG-CAAGGGCAAAAGCCGGCCTGACACGGCCCTTTA---CAAGGGGCCGTGGCGGGAAACCGCGGCCTAGCGAACCCCGGTA---GCCCCCGTGTGGGGCTTCGGGACGACGGA--AAAGCTACTCCGGGGGTAACAGCTTGGTCGCGGGCGAAAG-TTCCCATCGACCCCGCGGTTTGAGACCTCGATGTCGGCTCTTCTCACCCTGGCCGTGCAGCAGCGGCCAAGGGTGGGGGTGTTCACCCATTAAAGAGGAACGTGAGCTGGGTTTAG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Nitrosopumilus_maritimus_SCM1                           GGTTGATCCTG-CCGGACCTGACTGCTATCGGATTGATACTAAGCCATGCGAGTCGGCAGACGGCTCAGTAACGCGTAGTCAACCTACCCTATGGACGGGAATAACCT--CGG-GAAACTGAGTATAATGCCCGATAATGGTTTGTGTTCCAAACGCCGTAGGATGGGACTGCGGCCTATCA-GTTTGTTGGTGAGGTAATGGCCCACCAAGACTATTACAGGTACGGGCTCTGAGAGGAG-TAGCCCGGAGATGGGTACTGAGACACGGACCCAGGCCCTATGGGGCGCAGCAGGCGAGAAAACTTTGCAATGTGCGAAAGCACGACAAGGTTAATCCGAGTGCTTTTGACAGTCCTAGAAATAAGGGGTGGGCAAGTTCTGGTGTCAGCCGCCGCGGTAAAACCAGCACCTCAAGTGGTCAGGATGATTATTGGGCCTAAAGCATCCGTAGCCGGCTCTGTAAGTTTTCGGTTAAATCTGTACGCTCAACGTACAGGCTGCC-GGGAATACTGCAG-AGCTAGGGAGTGGGAGAGGTAGACGGTACTCGGTA-GGAAGGGGTAAAATCCTTTGATCTATTGATGACCACCTGTGGCGAAGGCGGTCTACCAGAACACGTCCGACGGTGAGGGATGAAAGCTGGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCCAGCTGTAAACTATGCAAACTCAGTGGTGCTGCAGGGAAGCCGTTAAGTTTGCCGCCTGGGAAGTACGTACGCAAGTATGAAACTTAAAGGAATTGGCGGGGGAGCACCACAAGGGGTGAA-GCCTGCGGTTCAATTGGAGTCAACGCCAGAAATCT-TACCCGGAGAGACAGCAG-AATGAAGGTCGCTGAAGACTTGAGAGGTGGTGCATGGCCGTCGCCAGCTCGTGCCGTGAGATGTCCTGTTAAGTCAGGTAACGAGCGAGATCCCTGCCTCTAGTTGCCAGTGGGGCGAATTAGCGGGACCGCCGTAGT-TAATACG-GAGGAAGGAAGGGGCCACGGCAGGTCAGTATGCCCCGAAACTCTGGGGCCACACGCGGGCTGCAATGGTAACGACAATGGGTTTCGAATCCGAAAGGATGAGGTAATCCTC-AAACGTTACCACAGTTATGACTGAGGGCTGCAACTCGCCCTCACGAATATGGAATCCCTAGTAACTGCGTGTCATT-ATCGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCGTTTCATTGAAGTGAGCGAACTTGAGGTTCGTGACAAGGGAAAAGTCGTAACAAGGTGACCGTAGGGGAACCTGCGGTCGGATCACCT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGCTGAAA-TGTTCTGAAACATAGAGGGTGATATCCCCGTAAGCGAACCCGAGTAGTTGTCCTTG---GTAGTGGGCAATGAATACAGGTGAAAGT-AGCATCTGAGGCTAAATATCTCTCAA-GACCGATAGTGGACT-AGTACCGTGAGGGAAAGCTGAAAAGTACCCCG-GAAGGGGGGCG-AAAAGTGCATGAAACCTATTACTTATCATGCGTTCCGTCTCGAAACACGGGCCAGGGAGCTAA-CTGTCATGGCAA-GCTTAAGTAGGCGAAGGGAAACCGAG-TTCTCGCAAGTCAT-GGCGGCTAGGCTAGAAGCCAGTCGATCTATTCCTGGGCTAGATGAAGGCGGG-CGAAAGCCCGCTGGAGGTCTT--AAGACGTTCTGACGTGCAAATCGTTGTTGTGACCTGGGAATAGGGGTCAAAAACCAATCTAGACTGG-CGCTCGCTAGTTCCAACCGAAGCGTCTCGCAGGGCGTGCTTTGTGGAGGTAGAG-CACTGATAGAGGGGAG-AAATCCCTCACCGCTCATTCAAACTCCGAAGG-ACACGGGTTCATGTGGCGTAAGGCTCAT-GACCGAAAG-GGGTTTAACCCAGACTGA-AGTTAAGGTCCCCAAATTTTTGCT-AAGTGTC--AAGCTAAAGAGCGTGTTCTCGCCAAGACAGCAGGGAGGTAAGCTCAGAAGCAGCTA-TCCTTTAAAAAGTGTGTAACAACTTACCTGCC----GAGGGGGGATGCCTCAAAAACGGAC-GGGGCTAAAGCAAAGTACCGATACTTTAGGTAGGTTG-GCGTAGTG-ATTGGGTCGAAGCA-GGGCGGTAACGTCCTGTGGAGCAGATCCTGGCGGCAGTA-ACAGCA-TAGTATGGTGAGAATCCATACCACC-GTAAGCGC-AAGGGTTTCCA-GGCAATGCGTTATCAGCCTGGAGGTAGTCGATC--CTAAGATGTACCG--AATGGGAAACTAGTTAATATTCTAGTACCTGCTTCCGGATAG-GGGAGTGTCGTATGACGAGAACCAGTT-CGAATTCCAGGAGACCATGAAACGTACCCAGAACCGACACAGGTGCGC-TGGCTTAGTA-AGCTAAGGTGCTACGGGTATACCGTATGGCGAGGGAATTCGGCAAATTAGTCCTGTAGCTTAGGTATAAGGGATGCCGCAGGTTGCAATGACAAGGGGGTTTCGACTGTTTAATAAAAACACAGGCGACTGCTAGTCCG-AAAGGATTTGTATAGTCGCTGAATCCTGGCCGGTGCCGGTACCTAAAACTTGGGTTCAAAAGGGCCGGTTAACGCCGGGAGTAACTCTGACTCTCTTAAGGTAGCCAAATGCCTTGTCGGGTAAGTTCCGACGCGCATGAATGGAACAACGAGAGCCCCACTGTCCCCGCCTACAACCCGGTGAAGCCACATAAGGTGGACGAACAGTCCATCGCCTTCCATCGGGGAGAGAAGACCCCGTGGAGTTTTACTGCAGCTTGTGCTTGGTAAGAATTGCACAGGGTATCTGGGAGCCATGCTTAAGAAGCAACGATGTAACACCAGACGACACGTGCAGGTGGGCAGTTCGGCTGGGGCGGCACCCCTTTGAAAAGATATCAAAGGGGCCCAAAGTTGAGTTCAAACGGGGCAGAAATCCGTTGAAGAGGG-CAAAGCCAAAAACTCGACTGAATGGATTTCCAAACGCACGGAATTCATAGACGAAAGTCTGGCTTAGCGATCCTTCGTGT--GCCCACTATTGGGGCCCGGAGGTGACAGA--AAAATTACCCCAGGGATAACAGGCTCGTCGCGGGCGAGAG-CTCCTATCGACCCCGCGGTTTGGTACCTCGATGTCGGCTTTTCCTATCCTGGTCCTGCAGCAGGGGCCAAGGGTGAGGCTGCTCGCCTATTAAAAGGGAACATGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGTCTCTGCCTGATGGAAGCGT--GAATAACTGAGGGGAAGTTGCTCCGAGTACGAGAGGAACAGAGCAGCGTGGCCACTGGTTTACCGGTTGTCGGCA--GGCCGGGCAGCTAAGCCGTTTAGGC-TAAGTGCTGAAAGCATCTAAGCACGAATCCTATCCCGAG-ACAAGTTATTAAGGTCGGCAGCAGAAGACTGCGTTGATAGGAAGGTGGTGTA------------------------
Picrophilus_torridus_DSM9790                            GGTTGATCCTG-CCGGCGGCCACTGCTATCAAGTTCCGACTAAGCCATGCGAGTCGGCGTACCGCTCAGTAACACGCGGATAATCTACCCTCGGGAAGGGCATAACCT--CGG-GAAACTGAGGCTAATTCCCTATAATGTTTGGATGGTGAAGCGCCCGGGGATGAGTCTGCGGCCTATCA-GGTAGTAGGTGGTGTAACGGACCACCTAGCCTAAGACGGGTACGGGCCCTGGGAGGGG-TAGCCCGGAGATGGACTCTGAGACACTAGTCCAGGCCCTACGGGGCGCAGCAGGCGCGAAACCTGTGCAATGCGCGCAAGCGCGACACGGGGAGCTTGAGTGCTTTTCTTATGCCTAAAAATAAGGGCTGGGTAAG-ACGGGTGCCAGCCGCCGCGGTAACACCCGCAGCTCAAGTGGTGGTCACTTTTACTGAGCCTAAAGCGTTCGTAGCCGGCTTTGTAAATCTCCAGGTAAATTCTAGCGCTTAACGTTAGATCTCCT-GGAGAGACTGCAA-AGCTTGGGACCGGGTGGGGTTGAACGTACTTTCAG-GGTAGGGGTAAAATCCTGTAATCCTGGAAGGACGACCGGTAGCGAAGGCGTTCAACTAGAACGGATCCGACGGTGAGGAACGAAGGCTAGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCTAGCTGTAAACTCTGCCCACTTGGTGGTGCCGGAGCGAAGGTGTTAAGTGGGCCGCTTGGGGAGTATGGTCGCAAGACTGAAACTTAAAGGAATTGGCGGGGGAGCACCGCAACGGGAGGA-ATGTGCGGTTTAATTGGATTCAACGCCGGAAAACT-CACCGGGAGCGACCTGTG-GATGAGAGTCCCTGACGAGTTGAGAGGTGGTGCATGGCCGTCGTCAGCTCGTACCGTAGGGCGTTCACTTAAGTGTGATAACGAGCGAGACCCCCATCTCCAATTGCAAGGTAAGCACTTTGGAGAGACCGCCAGCGC-TAAGCTG-GAGGAAGGAGGGGTCGACGGCAGGTCAGTACGCCCCGAATCTCCCGGGCTACACGCGCATTACAAAGGGCAGGACAATGCGTTGCAACCTCGAAAGGGGAAGCTAATCGCC-AAACCTGTCCGTAGTTAGGATTGAGGGCTGTAACTCGCCCTCATGAATCTGGATTCCGTAGTAATCGCGGGTCAAC-AACCCGCGGTGAATATGCCCCTGCTCCTTGCACACACCGCCTGTCAAACCATCCGAGCTGGCAAATCTGATGTCAGTGAGGAGGGTTAAGTCATAACAAGGTATCTGTAGGGGAACCTGCAGATG--------GGATGGTTTGGCTT-GAGAGCCGAAGAAGGACGTGCCAAGCTGCGAAATGCTCTGGGGAGGCGC-ATGGAGCCTTAGATCCAGAGATCTCCGAATGGGACCCCGGGAATCGAAACATCCTAGTACCGGGAGGAAAAGAAATCAATC-GAGA-TACCGTGAGTAAAGGCGATCGAAAGCGGTA-GAGGGCAAACATTCGAA--TAAGCTGGGACATAGAGGGTGATAGCCCCGTAGAAGAACCTGAGTACCATGCGTCG---TTATTCGCGTGGGAATACGGGTGGCATG-AACATCCAACCCTAAATACATCTCAA-GTCCGATAGCGAACA-AGTACCGTGAGGGAAAACTGAAAAGCAACCCG-GAAGGGCTGTG-AAAAGAGCCTGAAACCAGACAGTGATCCTATAGTCCGTGTTGAAGAACGGGCCAGGGAGTTGC-GACGGTTGGCAA-GGCTAAGGAGCCGTAGCGAAAGCGAT-TACCCGCAAGTCAG-CCGTGGCAGACCCGAAGCCGCTCGATCTACGCCTGAGTAGGTTGAAGCTTAG-CGAAAGCTAGGTGGAGGACCG--AACCGGTTCTGATGTGCAAATCGTTCGGATGACTTGGGTGTAGGGGTTAAAGGCTAATCTAGAGCGG-CAATAGCGGGTTCCCCCCGAAACTACCCGCAGGTAGACCTCCATGGAGGTAGAGCGACCGATTGGTAGTCG-AAAGACTGCGCCGGCCTATCAAACTCCGAAGGTGCTAGGGCATA---GGGATAAGCTTTAT-GCCCGTGAA-GGGAACAACCTAGACCTG-GATTAAGGCCTCTAAATACTGGCT-AAGTGCG----ATCTAAAAAGGTTTGCGGCCGAAGACAGTGGGGAGGTTGGCTTAGAAGCAGCCA-TCCTTTAAAGAGTGCGTAACAGCTCACTCACC----GAGGCTACATGCCTTGAAGATGGAA-GAGGCTAAAGCCAGTTGCCGAGATCCAGGGTAGGGGG-GCGTGCTG-TATGGGACGAAGCT-TCTTCGAGAGGAGGAGTGGAGCGGATCCTGGTAAAAGTA-GCAGTC-AAGAGTGGTGAGAATCCACTCCGCC-GAAAGGGC-AAAGGTTCCTT-GGCAATG-TTCGTCAGCCGAGGGTTAGCCGATC--CTAAGGCCATTCG--AAAGGGAAGCTGGTTAATATTCCAGCGCC-GCTTCGGGATAG-GGGAGAGTTGTATGACGTAAAGTCTGC-GAAATTCCTGGAGCCCATGAAACGTACCAAGAACCGACACAGGTGCCCCTGGATGAGAA-GTCCAAGGCGTTT-GGGAATAATGGA-CGCGAGGGAACTCGGCCAAATAGCTCCGTATCTTAGGTAGAAGGAGTGCCATAGGTCGCAGTGGCAAGGGGACCCCGACTGTTTACCAAAAACACAGATCACTGCTAGTCCG-TAAGGATGTGTATAGTGGTCGAAACCTGCCCAGTGCTGGTACCTGAAAGCTCCGCTCAAAAGGGCCAGTAAACGGCGGGGGTAACTATGACCCTCTCAAGGTAGCGTAATACCTAGCCGCTTAATTGGCGGCTTGCATGAA-GGTTCAACGAGAGTCCCACTGTCCCCGCGTTCAGCCCCGTGAAATTAA--TGTACTGGTGCACAATCCAGTCTCTCCCACGTGAAAGCGAAGTCCCCGTGGAGCTTTACTGCAGCCTGTAGCTGATTCTCAATGCGTAGGGTAGGAAGGAGCCATCG---AGAGGCGACGATGAAACACTTCCCGACAACTATTGGTGGGCAGTTTGGGTGGGGCGCCACGCCTCTAACAATCCAACAGAGGCCTCCAAAGGTCAGCTCAGGAGGGTCAGAAATCCTCCGTAGAGTA-TAAAGGCAAAAGCTGGCTTGACAGTGTTCCAGACAATAAGGAACGCTGATGCGAAAGCAGGGCTTAGCGAACCACCTTGTCTCCCTCTTCATGAGGGCAGGTGATAAGAGA--GAAGTTACCCCAGGGATAACTGAGTTGTCCTCGGCAAGAG-TACACATCGACCCGAGGGTTTGCTACTTCGATGTCGTCTGTTCCTATCCTGGCGCTGCATAAGACGCCAAGGGTGGGGCTGTTCGCCCATTAAAAGGGATCCTGAGATGGGTTCACTACGTCGCGAGACAGTAGGGTTGCTTCTCCGTGGGAGTGCT-CGATGCCTGAAGGGAAGGAGCCTTTAGTACGAGAGGAACGGGGGTTCGTGGCCTCTGGTTTACCGGTTGTCGGCAGTTGCCGGGTAGCTACGCCATACGCGAATAAAGGCTGAAAGCATCTAAGCCTGAAGTCGCCCCTGAA-AAGAGGCATCAGGTC-CCTCCTAAAAGAGGAGCTTGATAGGACCGGGATGTAAGGCATTAAGTCCACGGTTACTAA
Pseudomonas_entomophila                                 -----ATCATGGCTCAGATTGAACGCTGGCGGCAGGC--CTAACACATGCAAGTCGGCGGACGGGTGAGTAATGCCTAGG-AATCTGCCTGGTAGTGGGGGACAACGT--TTC-GAAAGGAACGCTAATACCGCATA-CGTCCTACGGGAGAAACGCTATCAGATGAGCCTAGGTCGGATTA-GCTAGTTGGTGGGGTAATGGCTCACCAAGGCGACGATCCGTAACTGGTCTGAGAGGAT-GATCAGTCACACTGGAACTGAGACACGGTCCAGACTCCTACGGGAGGCAGCAGTGGGGAATATTGGACAATGGGCGAAAGCCTGATCCAGCCATGCCGCGTGGCACTTTA-AGTTGGGAAATAAGCACCGGCTAAC--TCTGTGCCAGCAGCCGCGGTAATACAGAGGGTGCAAGCGTTAATCGGAATTACTGGGCGTAAAGCGCGCGTAGGTGGTTCGTTAAGTTGGATGTGAAAGCCCCGGGCTCAACCTGGGAACTGCA-TCCAAAACTGGCG-AGCTAGAGTATGGTAGAGGGTGGTGGAATTTCCTG-TGTAGCGGTGAAATGCGTAGATATAGGAAGGAACACCAGTGGCGAAGGCGACCACCTGGACTGATACTGACACTGAGGTGCGAAAGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCCGTAAACGATGTCAACTAGCCGGTGGCGCAGCTAACGCATTAAGTTGACCGCCTGGGGAGTACGGCCGCAAGGTTAAAACTCAAATGAATTGACGGGGGCCCGC-ACAAGCGGTGGA-GCATGTGGTTTAATTCGAAGCAACGCGAAGAACCT-TACCAGGCCTTGACATGCAGA-GAACTTTGATGGATTGGTCACAGGTGCTGCATGGCTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGTAACGAGCGCAACCCTTGTCCTTAGTTACCAGGTGGGCACTCTAAGGAGACTGCCGGTGA-CAAACCG-GAGGAAGGTGGGGATGACGTCAAGTCATCATGGCCCTTACGGCCTGGGCTACACACGTGCTACAATGGTCGGTACAGAGGGTTGCCAAGCCGCGAGGTGGAGCTAATCTCACAAAACCGATCGTAGTCCGGATCGCAGTCTGCAACTCGACTGCGTGAAGTCGGAATCGCTAGTAATCGCAAATCAGA-ATGTTGCGGTGAATACGTTCCCGGGCCTTGTACACACCGCCCGTCACACCATGGGAGTGGGCCACGGTGTGATTCATGACTGGGGTGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGCCTTGGCAGTCAGAGGCGATGAAAGACGTGGTAGCCTGCGATAAGCTTTGGGGAGTCGGCAAACAGACTGTGATCCAGAGATCTCTGAATGGGACCAGGGGAACTGAAACATCTAAGTACCCTGAGGAAAAGAAATCAACC-GAGA-TTCCCTTAGTAGTGGCGAGCGAACGGGGAC-CAGCCCTTA--AGTGGAA-CGCTCTGGAACATAGTGGGTGATAGCCCCGTACACGAAATCGAGTAGGACGGAGCACGAGAAACTTTGTCTGAACATGGGGGG-ACC-ATCCTCCAAGGCTAAATACTACTGACTGACCGATAGTGAACC-AGTACCGTGAGGGAAAGGCGAAAAGAACCCCGGAGAGGGGAGTGAAATAGAACCTGAAACCGTATGCGTATGACTGCGTACCTTTTGTATAATGGGTCAGCGACTTA-TATTCAGTGGCGA-GCTTAAGGAGGCGTAGCGAAAGCGAG-TCTTAATAAGTCGCTGGGTATA-GACCCGAAACCGGGCGATCTATCCATGGGCAGGTTGAAGGTTAG-GTAACACTGACTGGAGGACCG---AACCGACTACCGTTGAAAAGTTAGCGGATGACCTGTGGATCGGAGTGAAAGGCTAATCAAGCTCGG-AGATAGCTGGTTCTCCTCGAAAGCTATTTAGGTAGCGCCTCATG--TAGTAGAGC-ACTGTTTCGGGTCATCCCGACTTACCAAACCGATGCAAACTCCGAAGGGAGACACACGGCGG-GTGCTAACGTCCGT-CGTGAAAAG-GGAAACAACCCAGACCGTCAGCTAAGGTCCCAAAGTCATGGTT-AAGTG-------GGAAACGATGTGGGAAGGCTTAGACAGCTAGGAGGTTGGCTTAGAAGCAGCCA-CCCTTTAAAGAAAGCGTAATAGCTCACTAGTC----GAGTCGGCCTGCGCGGAAGATGTAACGGGGCTCAAACCATGCACCGAAGCTACGGGTAGAGGA-GCGTTCTGTAAGCCTGTGAAGGTGA-GTTGAGAAGCTTGCTGGAGCGAATGCTGACATGAGTA-ACGACA--ATGCGAGTGAAAAACTCGCACGCC-GAAAGACC-AAGGTTTCCTG-CGCAACG-TTAATCGACGCAGGGTTAGTCGGTC-CCTAAGGCGAGGCGTCGATGGAAAACAGGTTAATATTCCTGTACTCGGAGAAGGCTAG-GGCAAATCCGG-CAAGGCCGAGAGCT--GATATGCCATGCTTCCAAGAAACGTACCCCAAACCGACACAGGTGGTTAGGTA-GAGAA-TACCAAGGCGC-TTGAGAGAACTCGG--GTGAAGGAACTAGGCAAAATGGCACCGTAACTTCGGGAGAAGGTGCGCCGCCGGTCGAAGATACCAGGCCGCTGCGACTGTTTATTAAAAACACAGCACTCTGCAAACACG-AAAGTGGACGTATAGGGTGTGACGCCTGCCCGGTGCCGGAAGGTTAATTGATGGGGTTAAAGCCCCGGTAAACGGCGGCCGTAACTATAACGGTCCTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCTGCACGAATGGCGTAACGATGGCGGCGCTGTCTCCACCCGAGACTCAGTGAAATTGA--AATCGCTGTGAAGATGCAGTGTATCCGCGGCTAGACGGAAAGACCCCGTGAACCTTTACTATAGCTTTGCACTGAGCTTGCTTGTGTAGGATAGGTGGGAGGCTTTG---AGAGCCATCCTTGAAATACCACCCGACAGTGTATGGTGGGTAGTTTGACTGGGGCGGT-CTCCTCCCAAAGAGTAACGGAGGAGTACGAAGGTGCGCTCAGACCGGTCGGAAATCGGTCGTAGAGTA-TAAAGGCAAAAGCGCGCTTGACTGCGAGACAAA---CACGTCGAGCAGGTACGAAAGTAGGTCTTAGTGATCCGGTGGTT---CTGTATGGAAGGGCCATCGCTCAACGGATAAAAGGTACTCCGGGGATAACAGGCTGATACCGCCCAAGAG-TTCATATCGACGGCGGTGTTTGGCACCTCGATGTCGGCTCATCACATCCTGGGGCTGAAGCCGGTCCCAAGGGTATGGCTGTTCGCCATTTAAAGTGGTACGCGAGCTGGGTTTAGAACGTCGTGAGACAGTTCGGTCCCTATCTGCCGTGGACGTT-TGAGATTTGAGAGGG-GCTGCTCCTAGTACGAGAGGACCGGAGTGGACGAACCTCTGGTGTTCCGGTTGTCGGCAT-TGCCGGGTAGCTATGTTCGGAAGAGATAACCGCTGAAAGCATCTAAGCGGGAAACTTGCCTCAAG-ATGAGATCTCAAGGGCCGTCGAAGACTACGACGTTGATAGGTTGGGTGTGTAAGGCGTTGAGCTAACCAATACTAA
Pyrobaculum_arsenaticum_DSM                             GGTTGATCCTG-CCGGACCCGACCGCTATCGGGGTAGGGCTAAGCCATGCGAGTCGGCGCACGGCTCAGTAACACGTGCCCAACCTACCCTCGGGAGGGGGACACCCC--CGG-GAAACTGGGGCCAATCCCCCATAAGGCCCCTTCCCCAAAACGCCCGAGGATGGGGGCACGGCCCATCA-GGTAGTTGGCGGGTTAAAGGCCCGCCAAGCCGAAGACGGGTAGGGGCGGTGAGAGCCGCGAGCCCCGAGATCGGCACTGAGACAAGGGCCGAGGCCCTACGGGGTGCAGCAGGCGCGAATACTCCGCAATGCGGGCAACCGCGACGGGGCTACCCCGAGTGCTTTTGCCCGGTCTAAAAATAAGTGGGGGGCAAG-TCTGGTGTCAGCCGCCGCGGTAATACCAGCCCCACGAGTGGTCGGGGTGTTTACTGGGCTTAAAGCGCCCGTAGCCGGCCCGGCAAGTCGCTCCTGAAATCCCCGGGCCCAACCCGGGGGCGGGG-GGCGATACTGCCG-GGCTAGGGGGCGGGAGAGGCCGCCGGTACTCCGGG-GGTAGGGGCGAAATCCGTTAATCCCCGGAGGACCACCAGTGGCGAAAGCGGGCGGCCAGAACGCGCCCGACGGTGAGGGGCGAAAGCCGGGGGAGCAAAGGGGATTAGATACCCCTGTAGTCCCGGCCGTAAACGATGCGGGCTAGCTGGTGGCGAAGGGAAACCGTTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGGGCACCACAAGGGGTGAA-GCTTGCGGCTTAATTGGAGTCAACGCCGGAAACCT-CACCCGGGGCGACAGCAG-GATGAAGGCCGCTAACGACCTGAGAGGAGGTGCATGGCCGTCGTCAGCTCGTGCCGTGAGGTGTCCGGTTAAGTCCGGCAACGAGCGAGACCCCCGCCCCTAGTTGCTAGGGGGGCACACTAGGGGGACTGCCGGCG--TAAGCCG-GAGGAAGGAGGGGGCCACGGCAGGTCAGTATGCCCCGAAACCCCGGGGCTGCACGCGAGCTGCAATGGCGGGGACAGCGGGAACCGACCCCGAAAGGGGGAGGCAATCCCGTAAACCCCGCCCCAGTAGGGATCGAGGGCTGCAACTCGCCCTCGTGAACGTGGAATCCCTAGTAACCGCGTGTCACC-AACGCGCGGTGAATACGTCCCTGCCCCTTGCACACACCGCCCGTCGCACCACCCGAGGGAGCGAGCAGGGGGCTCCCAAGGGGGGTGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGGCTCGGCTC-GGGCGCCGAAGAAGGGCGTGGCAAGCTGCGATAAGCCCGGGGGAGCCGC-AGGCAGGCTTAGAACCCGGGATCCCCGAATGGGACGCGGGGAACGGAAACATCTTAGTACCCGCAGGAAGAGAAGCCAACA-GGGA-ACCCCTGAGTAGGGGCGACCGAAAGGGGGA-GAGCCCAAACAGCCGAAG-TGGGCTGGAACGTAGAGGGTGACAGCCCCGTAGGCTAACCGGAGTACCACGGCTTA---GTTTTGCCGTGGGAACACGCCGGCCACT-GGCCGGCAAGGCTAAGCACGTCCCGA-GTCCGATAGCGCACT-AGTACCGTGAGGGAAAGCTGAAAAGAACCCCG-GAAGGGGGGTG-AAAAGAGCCTGAAACCGGGCGGCTATCCGCCCTTACGTCTAGAAACACGGGCCGGGGAGTGCA-CGGCCGTGGCGA-GCCTAAGGAGGCGCAGGGAAACCGAC-AGCCCGCAAGTCAC-GGCCGTGCGACCAGAAACCGGGCGATCTAGCCCTGGGCAGGGCGAAGCGGGG-CGAAAGCCCCGTGGAGGCCCG--AAGGGGTTCTGATGTGCAAATCGTTCCCATGACCTGGGGCTAGGGGCAAAAGACCAATCAAGCCCGG-TGATAGCTGGTTCCCCCCGAAGCGGGTCCCAGCCCGGCCTCCCCGGAGGTAGAG-TACTGATCGGGAGCCG-AAAGGCTCCGGCCCCCGGTCAAACTCCGAAGG-AGGCGGGGGCGGT-GGGGTAAGCCTCCG-CTCCGAGAC-GGGAATAACCGAGACCGG-GGTTAAGGCCCCCAAGTGCGGGCT-TAGTGTC-AATCTCGAAGGGCGTCCTCCGCCCAAGACAGCGGGACCGTGGGCCTAACAGCAGCCA-TCGGCTAAGCAACGCGTAACAGCGGACCCGCC----GAGGCGGGGGGCCCCGAAGATGTACAGGGACT-AAGCCCGCCGCCGATACCCCGGGTAGGGGG-GCGCGGCC-GTGGGGCAGAAGCC-GGGCCGTGAGGTCCGGTGGAGAAGATCCCGGCGGTAGTA-GCAGCG-AAGAGGGGTGAGAAGCCCCTCCGCCGGAAAGGAC-CAGGGTTTCCT-GGCAACT-TCAATAGGCCAGGAGTTAGCCGGTC--CTAAGGCGGGGCG--AAAGGGAAACGGGTTAATATTCCCGTGCCCGCCTCGGGATAG-GGGAGTGCCGTACGGCGAGAACCGGCC-GAAATTCCTGGGGCCCGTGAAACGTACCGAGAACCGACGCAGGTGCTCCTGGGTGAAAA-GCCCAAGGCGGCTCGGGTG-ACCCCG-GGCCAGGGAACTCGGCAAATTGGCCCCGTAACTTCGGGAGAAGGGGTGCCGCAGGTCGCAGTGGCAAGGGGGACCTGACTGTTTAACAAAAACATAGGTCCCCGCGAGCCCG-TAAGGGTGAGTACGGGGGCTGAATCCTGGCCACTGGCGGTACGTGAACCCCGGGTACAAAAGCGCCGCTGAAGGCCGGGGGTAACTCTGACCCTCTTAAGGTAGCCAAATGCCTTGCCGGGTAAGTTCCGGCGTGCATGAATGGATCAACGAGGTCCCCACTGTCCCGGCCCGGGGCCCGGCGAACCCAC---CTCCAGGTGCACAGTCCTGGGACCCCCGACGGGGCGAGAAGTCCCTGTGGAGCTTCACAGCAGCCTGTCGTTGGCGGGGGGTGCAGAGCGTAGGTGGGAG-CGATG---AGATGCGGCCCTGGAACACCACCCGACAGCGGCAGGCGGGCTGTTCGGCTGGGGCGGCACACCCCTGAAAAGATATCGGGGGTGCCCAAAGCTCGGCTCAGGCGGGTCAGAAATCCGCCGTAGAGTG-TAAGGGCAAAAGCCGGGCTGACTGGGCCCTTGAACGCAAGGGGCCCAGGCGGGAAACCGGGGCCTAGAGAACGCTCGTGC--CCCCACCAGTGGGGGCCGGGCATGACAGA--AAAGTTACCCCAGGAATAACCGGCTCGTCGCGGGTGAGAG-TCCCCATCGACCCCGCGGTTTGGTACCCAGACGTCGTCTCTTCCCATCCTGGCGGTGCAGCAGCCGCCAAGGGTGGGGCTGCCCGCCCATTAAAGGGGAACGTGAGATGGGTTCAGACCGTCGCGAGACAGGTCGGTCTCTACCTGTCGGGGGCGTT-GGCCGCCTGAGGGGAAGGTGCCCTCAGTACGAGAGGAACGGGGCGCCGCGGCCTCTAGTGTACCGGTTGTCGGCA-CTGCCGGGCAGCCACGCCGTGTGGGGATAACCGCTGAACGCATCTAAGCGGGAAGCCCTCCCCGAG-ACGAGGCGGCAGGGC-TCCCGTAGAAGACGGGG-------------------------------------------
Pyrococcus_abyssi_GE5                                   GGTTGATCCTG-CCGGAGGCCACTGCTATGGGGGTCCGACTAAGCCATGCGAGTCGGCGGACGGCTCAGTAACACGTCGGTAACCTACCCTCGGGAGGGGGATAACCC--CGG-GAAACTGGGGCTAATCCCCCATAAGGTCCCCAGGCCGAAACGCCCGAGGATGGGCCGGCGGCCGATTA-GGTAGTTGGTGGGGTAACGGCCCACCAAGCCGAAGATCGGTACGGGCCGTGAGAGCGG-GAGCCCGGAGATGGACACTGAGACACGGGTCCAGGCCCTACGGGGCGCAGCAGGCGCGAAACCTCCGCAATGCGGGAAACCGCGACGGGGGGACCCCCAGTGCTTTTCCGGAGTGTAAAAATAAGGGCTGGGCAAG-GCCGGTGGCAGCCGCCGCGGTAATACCGGCGGCCCGAGTGGTGGCCACTATTATTGGGCCTAAAGCGGCCGTAGCCGGGCCCGTAAGTCCCTGGCGAAATCCCACGGCTCAACCGTGGGGCTCGCTGGGGATACTGCGG-GCCTTGGGACCGGGAGAGGCCGGGGGTACCCCCGG-GGTAGGGGTGAAATCCTATAATCCCGGGGGGACCGCCAGTGGCGAAGGCGCCCGGCTGGAACGGGTCCGACGGTGAGGGCCGAAGGCCAGGGGAGCGAACCGGATTAGATACCCGGGTAGTCCTGGCTGTAAAGGATGCGGGCTAGGTGGTGCCGTAGGGAAGCCGTTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACTACAAGGGGTGGA-GCGTGCGGTTTAATTGGATTCAACGCCGGGAACCT-CACCGGGGGCGACGGCAG-GATGAAGGCCGCTGAAGGTCTGAGAGGAGGTGCATGGCCGCCGTCAGCTCGTACCGTGAGGCGTCCACTTAAGTGTGGTAACGAGCGAGACCCGCGCCCCCAGTTGCCAGGGAGGCACTCTGGGGGGACTGCCGGCGA-TAAGCCG-GAGGAAGGGGCGGGCGACGGTAGGTCAGTATGCCCCGAAACCCCCGGGCTACACGCGCGCTACAATGGGCGGGACAATGGGTGCCGACCCCGAAAGGGGGAGGTAATCCCCTAAACCCGCCCTCAGTTCGGATCGCGGGCTGCAACTCGCCCGCGTGAAGCTGGAATCCCTAGTACCCGCGCGTCATC-ATCGCGCGGCGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCACTCCACCCGAGCGGGCGAGCCTAGGCTCCGTGAGGGGGGAGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTACGGCTCGATCA---GGATGGCTCGGCTCGGGGCGCCGACGAAGGGCGTGGCAAGCTGCGATAAGCCCCGGCGAGGCGC-AGGCAGCCGTCGAACCGGGGATTCCCGAATGGGACGCGGGGAATTGAAACATCTTAGTACCCGCAGGAAAAGAAAGCAAAA-GCGA-TGCCGTGAGTAGGGGCGACCGAAAGCGGCA-CAGGGCAAACAGCCGAAG-TCCGCTGGAACGGAGAGGGTGATAGCCCCGTAGGCGTACCTGAGTACCGTCGGTTG---GATATCCGGCGGGAAGCTGGGAGGCATC-GGCTCCCAACCCTAAATACGTCCCGA-GACCGATAGCGAACT-AGTACCGTGAGGGAAAGCTGAAAAGCACCCCG-GGAGGGGGGTG-AAAAGAGCCTGAAACCGGGCGGCGATTGCACCGTCCGTCTTGAAACACGGGGCAGGGAGTTCG-CGGCCGTGGCGA-GGTTAAGTAGCCGTAGGGAAACCGACATGCCCGCAAGTCAC-GGCCGCGAGACCCGAAACCGGTCGATCTAGCCCGGGGCAGGGTGAAGTCCCT-CAACAGAGGGATGGAGGCCCG-CTAGGGGTGCTGATGTGCAGTTCGCTCCCGTGACCCCGGGCTAGGGGTGAAAGGCCAATCGAGGCCGG-AGATAGCTGGTTCCCGCCGAATCATCCCGCAGGATGGCCTCCCCGGAGGTAGAG-CACTGATTGGGGGGCG-AAAGCCCCCGGCCCCCTGTCAAACTCCGAAGG-AGTAGGGTGGC---GGTGTAAGCC-GTC-CACCGAGAG-GGGAACAACCCAGACCGG-GGTTAAGGCCCCAAAGTGCCGGCT-AAGTGTT--ACTCCAAAGGGTGTCCCGGGCCTTAGACAGCGGGGAGGTAGGCTTAGAAGCAGCCA-TCCTTTAAAGAGTGCGTAACAGCTCACCCGTC----GAGGTCCGGGGCCCCGAAAATGGAC-GGGGCTCAAGCCGGCCGCCGAGACCCCGGGTAGGCGG-GCGTGCCG-GTGGCGTAGAAGCC-GGGCCGTAAGGTCCGGTGGAGCGGATCCTGCCGGGAGTA-GCAGCG-TAGTCGGGTGAGAATCCCGACCGCC-GGAGGGGC-CAGGGTTCCACAGGCAATG-GTCGTCAGCCGTGGGTTAGTCGGTC--CTAACCCCGCCCG--AAAGGGAAACGGGTTAATATTCCCGTACCCGCCTCGGGGTAG-GGGAGTGCCGTATGGCGAGAACCGGGT-GAAATCCCTGGGGCCCGTGAAACGTACCGAGAACCGACACAGGTGCCCCTGGGTGAGAA-GCCTAAGGCGTGTCGGGGGAAACCCG-GCCGAGGGAACTCGGCAAACTGGCCCCGTAACTTCGGGAGAAGGGGTGCCGCAGGTCGCAGTGACTAGGGGGGCCCGACTGTTTAATAAAAACACAGGTCCCAGCTAGCCCG-AAAGGGTTTGTACTGGGGCCGACGCCTGCCCAGTGCCGGTATGTGAAGCCCGGGTACAAAAGCACCGGTAAACGGCGGGGGTAACTATAACCCTCTTAAGGTAGCGAAATTCCTTGTCGGTTAAATGCCGACCTGCATGAATGGCGTAACGAGGTCCCCGCTGTCCCCGGCCGGGGCCCGGCGAAACCTC---TGCCTGGCGCGCATGCCAGGGACCCCCGGTGGGAAGCGAAGACCCCATGGAGCTTTACTGCAGCCTGCCGTTGGCGAGGGGTGCGCAGCGTAGGCGGGAGGCGTCG---AGAGCCGTCCATGAGACACCGCCCGACAGCGGTAGGTGGGCAGTTTGGCTGGGGCGGCACGCCCCCGAAAAGGTATCGGGGGCGCCCTAAGGTCGGCTCAGGCGGGTCAGGAATCCGCCGTAGAGTG-CAAGGGCAAAAGCCGGCCTGACTGGACCCGTAACAGAGGCGGGTCCAGCCCCGAAAGGGTGGCCTAGCGAACCCCTGTG---CCTCCCCGGTGGGGGCCAGGGATGACAGA--AAAGCTACCCTGGGGATAACAGAGTCGTCTCGGGCGAGAG-CCCATATCGACCCCGAGGCTTGCTACCTCGCTGTCGGCTCTTCCCATCCTGGCCCTGCAGCAGGGGCCAAGGGTGGGGGTGTTCACCCATTAAAGGGGAACGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGATGCTATCTACCGGGGGTGTT-GGCCGCCTGAGGGGAAGGTGCCCTTAGTACGAGAGGAACAGGGCGCCGCGGCCTCTGGTCTACCGGTTGTCGGCA-TCGCCGGGCAGCTACGCCGCAGCCGA-TAAGGCCTGAAGGCATCTAAGGCCGAAGCGGCCCCCGAA-AATAGGCGGCAGGGC-TCGGGTAGAAGACCCGGTTGATGGGGCGGGGATGTAACCCGCTTAGTCTGCCGCCCCCAA
Staphylothermus_marinus_F1                              GGTTGATCCTG-CCGGACCCGACCGCTATCGGGGTGGGGCTAAGCCATGGGAGTCGGCGGACGGCTGAGTAACACGTGGCTAACCTACCCTCGGGAGGGGGATAACAC--CGG-GAAACTGGTGCTAATCCCCCATAAGGGTTCCTCCCCGAAACGCCCGAGGATGGGGCTGCGGCCCATCA-GGTAGTTGGCGGGGTAACGGCCCGCCAAGCCGATAACGGGTAGGGGCCGTGAGAGCGG-GAGCCCCCAGATGGGCACTGAGACAAGGGCCCAGGCCCTACGGGGTGCACCAGGCGCGAAACCTCCGCAATGCGGGCAACCGTGACGGGGTCACCCCGAGTGCTTTTCCCCGCTGTAGGAATAAGCGGGGGGCAAG-TCTGGTGTCAGCCGCCGCGGTAATACCAGCCCCGCGAGTGGTCGGGACGATTATTGGGCCTAAAGCGCCCGTAGCCGGCCTGGCAAGTCCCCTCCTAAATCCCCGGGCTCAACCCGGGGAGTGGA-GGGGAAACTGCCA-GGCTAGGGGGCGGGAGAGGCCGAGGGTACTCCCGG-GGTAGGGGCGAAATCCTATAATCCCGGGAGGACCACCAGTGGCGAAGGCGCTCGGCTGGAACGCGCCCGACGGTGAGGGGCGAAAGCCGGGGGAGCGAACCGGATTAGATACCCGGGTAGTCCCGGCTGTAAACGATGCGGGCTAGGTGGTGCCGCAGGGAAGCCGTTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAAGGGGTGGA-GCCTGCGGTTTAATTGGAGTCAACGCCGGGAACCT-CACCGGGGGCGACAGCAG-GATGACGGCCGCTAACGGCCTGAGAGGAGGTGCATGGCCGTCGCCAGCTCGTGCCGTGAGGTGTCCGGTTAAGTCCGGCAACGAGCGAGACCCCCGCCCCTAGTTGCGACCGGGGCACACTAGGGGGACTGCCGCCGTATAAGGCG-GAGGAAGGAGGGGGCCACGGCAGGTCAGCATGCCCCGAATCCCCCGGGCTACACGCGGGCTACAATGGCGGGGACAGCGGGATCCGACCCCGTAAGGGGGAGGCAATCCCTCAAACCCCGCCGCAGTTGGGATCGAGGGCTGCAACTCGCCCTCGTGAACGTGGAATCCCTAGTAACCGCGCGTCATC-ATCGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCGCTCCACCCGAGGGAGCGAACTCTCCCCTCCCAAGGGGGGAGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGGCTCGGCTC-GGGCGCCGAGGAAGGCCGTGGCAAGCTGCGATAAGCCCGGGGTAGGCGC-ATGCAGCCGTTGAACCCGGGATCGCCGAATGGGACCCCCCGAACGGAAACATCTTAGTAGGGGGAGGAGGAGAAACCACCACGGGA-TCCCCTGAGTAGGGGCGACCGAAAGGGGGA-GAGCCCAAACAGCCGAAG-TGGCCTGGAACGTAGAGGGTGAAAGCCCCGTAGGCTAACCAGAGTACCACGGCTTG---GTTTTGCCGTGGGAAGCCGGGAGGCACC-GGCTTCCAAGGCTAAATACGTCCCGA-GACCGATAGCGTACTAAGTACCGTGAGGGAAAGCTGAAAAGTACCCTG-GAAAGGGGGTG-AAAAGAGCCTGAAACCGGGCGGCTATTGCGCCGTCCGTCTTGAAACACGGGCCGGGGAGTCCA-CGGCAGTGGCGA-GCCTAAGTAGGCGTAGGGAAACCGACAAGCCCGCAAGTCAC-TGCCGTGGGACCAGAAACCGGGCGATCTAGGCGGGGGCAGGGTGAAGCCGGG-GGAAACCCCGGTGGAGGCCCG--CAAGGGTTCTGACGTGCAATTCGTTCCCCTGACCCCCGTCTAGGGGCAAAAGACCAATCTAGCCCGG-TGATAGCTGGTTCCCGCCGAAGTGGCTCTCAGGCCAGCCCCGCCAGAGGTAGAGCTACGGATTGGGGGGCG-AAAGCCCCCGGCCCCCTATCCAACTCCGAAGG-AGTGGGGCTCCCC-GGGGTAAGCCCGGG-GGCCGAGAG-GGGAACAACCCAGACCGG-GGTTAAGGCCCCAAAGTGCCGGCT-AAGTGCC-AAGCCCAAAGGGCGTCCCGCGGCTTAGACAGCGGGGAGGTGGGCCTAACAGCAGCCA-TCCTCTAAGGAGTGCGTAACAGCTCACCCGCC----GAGCCGCGGGGCCCCGAAGATTGGTCGGGGCTCAAGCCGGCCGCCGAGACCCCGGGTAGGCGG-GCGCCGGG-TCGGGGCAGAAGCC-GGGCCGAGAGGTCCGGTGGAGTGGATCCCGGCGGCAGTA-GCAGCG-AAGAGGGGTGGAAATCCCCTCCGCCGGAAAGGGC-CAGGGTTCCTC-GGCAACG-GTCGTCGGCCGAGGGTTAGCCGGCC--CTAACCCGGGCCG--AAGGGGAAACGGGTTAATATTCCCGTGCCCGCCTCCGGATAG-GGGAGAACCGTATGGTGAGAAGGGGCC-GAAACTCCGGGGGCCCATGAAACGTACCGAGAACCGACACAGGTGCCCCTGGGTGAGTA-GCCCCAGGCGTCTGGGGGATAACCCG-GGCCAGGGAACTCGGCAAATTGGCCCCGTAACTTCGGGAGAAGGGGTGCCGCGGGTCGCAGTGCCTAGGGGGGCCTGACTGTTTAATAAAAACATAGGTCCCCGCAAGCCCG-AAAGGGTGTGTACGGGGGCTGAATCCTGGCCACTGGCGGTCCGTGAAACCGGGGTACAAAAGCGCCGCTGAAGGCCGGGAGTAACTCTGACTCTCTTAAGGTAGCCAAATGCCTTGCCGGGTGAGTTCCGGCGCGCATGAATGGATCAACGAGGTCCCCACTGTCCTGGCCCGGGGCCCCGCGAATACAC--GGAGCCGGTGCACAGGCCGGCAACCCCCCGCAGGGCGATAAGACCCCGTGGAGCTTCACCGCAGCCTGGCGTTGGGCTGCGGCGCGTAGCGTAGGTGGGAGCCAGTG---AGAGGCGCCAATGAAACACCACCCGACAGCGTCAGGTGGGCGGTTTGGCTGGGGCGGCACGCCCGCGAAAAGGTAACACGGGCGCCCAAAGGTCGGCTCAGGCGGGTCAGAGCTCCGCCGTAGAGTG-CAAGGGCAAAAGCCGGCTTGACCGGACCCCGGAACACAACGGGTCCGGCCGGGAAACCGCGGCCTAGCGAACGCTCGTGC--CCCCCTCGGTGGGGGCCGGGCATGACAGA--AAAGTTACCCCGGGGATAACAGAGTCGTCGCGGGCGAGAG-CTCCCATCGACCCCGCGGTTTGCTACATCGATGTCGGCTCTTCCCATCCTGGGAGTGCAGCAGCTCCCAAGGGTGGGGCTGCCCGCCCATTAAAGGGGAACGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGACTCTACCCGCGGGGGGTGTG-GGCCGCCTGAGGGGAAGGTGCCCTCAGTACGAGAGGAACGGGGCGCCGCGGCCAATGGTGTACCGGTTGTCGGCA-TAGCCGGGCAGCCACGCCGTAGGGGG-TAACCGCTGAAAGCATCTAAGCGGGAACCCCTCCCCGAA-AAGAGGCGGCAGGGC-TCCCGTAGAAGACGGGGTTGATGGGGCGGGGGTGTAAGGGGTTTAGCCCGCCGCTCCCAA
Sulfolobus_acidocaldarius_DSM_639                       ----GATCCTG-CCGGACCCGACCGCTATCGGGGTAGGGATAAGCCATGGGAGTCGGCGGACGGCTGAGTAACACGTGGCTAACCTACCCTCGGGACGGGGATAACCC--CGG-GAAACTGGGGATAATCCCCGATAATGGTTCCTTCCCTAAACGCCCGAGGATGGGGCTACGGCCCATCA-GGCTGTCGGTGGGGTAAAGGCCCACCGAACCTATAACGGGTAGGGGCCGTGGAAGCGG-GAGCCTCCAGTTGGGCACTGAGACAAGGGCCCAGGCCCTACGGGGCGCACCAGGCGCGAAACGTCCCCAATGCGCGAAAGCGTGAGGGCGCTACCCCGAGTGCTTTTCCCCGCTCTAAAAATAAGCGGGGGGCAAG-TCTGGTGTCAGCCGCCGCGGTAATACCAGCTCCGCGAGTGGTCGGGGTGATTACTGGGCCTAAAGCGCCTGTAGCCGGCCCACCAAGTCGCCCCTTAAAGTCCCCGGCTCAACCGGGGAACTGGG-GGCGATACTGGTG-GGCTAGGGGGCGGGAGAGGCGGGGGGTACTCCCGG-AGTAGGGGCGAAATCCTTAGATACCGGGAGGACCACCAGTGGCGGAAGCGCCCCGCTAGAACGCGCCCGACGGTGAGAGGCGAAAGCCGGGGCAGCAAACGGGATTAGATACCCCGGTAGTCCCGGCTGTAAACGATGCGGGCTAGGTGGTGCCGCAGGGAAGCCGTTAAGCCCGCCGCCTGGGGAGTACGGTCGCAAGACTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAAGGGGTGGA-ACCTGCGGCTCAATTGGAGTCAACGCCTGGAATCT-TACCGGGGGAGACCGCAG-TATGACGGCCGCTAACGACCTGAGAGGAGGTGCATGGCCGTCGCCAGCTCGTGTTGTGAAATGTCCGGTTAAGTCCGGCAACGAGCGAGACCCCCACCCCTAGTTGGTACAGAACCACACTAGGGGGACTGCCGGCG--TAAGCCG-GAGGAAGGAGGGGGCCACGGCAGGTCAGCATGCCCCGAAACTCCCGGGCCGCACGCGGGTTACAATGGCAGGGACAACGGGATGCTACCTCGAAAGGGGGAGCCAATCCTT-AAACCCTGCCGCAGTTGGGATCGAGGGCTGAAACCCGCCCTCGTGAACGAGGAATCCCTAGTAACCGCGGGTCAAC-AACCCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCGCTCCACCCGAGCGAGCGAACTCCTTTCCCGCGAGGGGGGAGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCAC------GGCTCGGCTC-GGGCACCGAAGAAGGGCGCGGCAAGCAGCGAAATGCTCGGGTGAGGCGC-AAGCAGCCGTTGACCCCGAGGTCCCCTAATGGGACCCCCCGAACGGAAACATCTTAGTAGGGGGAGGAAAAGAAATCAATT-GAGA-TCCCCTGAGTAGGGGCGACCGAAAGGGGGA-CAGCCCAAACAGCCGAAC-TCCCCTGGAACATAGAGGGTGAAAGCCCCGTAGGCTAAGTAGAGTACCATCCCCTG---GTTTGGGGGTGGGAAGTTAGGGGACACG-TGCCTCTAAGGCTAAATATGTCCCGA-GACCGATAGCAAACTAAGTACCGTGAGGGAAAGCTGAAAAGAACCCCGGAAGGGGGAGTG-CAAAGAGCCTGAAACCGGGTGGTTATCACGCCTTTCGTCTTGAAACACGGGCCGGGGAGTTCA-CATCAGTGGCGA-GCTTAAGAAGGCATAGGGAAACCAAG-TGCCCGCAAGCCAC-TGATGTGAGGCTAGAAACCGGGCGATCTAGTCCGGGGCAGGCTGAAGGTGGG-GGAAACCCCACTGGAGGGCCGAATAGGGGTTCTGACGTGCAATTCGTTCCCTTGACCTCGGACTAGGGGCAAAAGACCAATCTAGCCCGG-TGATAGCTAGTTCCCCCCGAAATGCGTCCTAGCGCAGCCTCCCTAAAGGTAGAGTGACAGATCGG-AGGCG-AAAGCCTGGGGCTTCCGGTCTAACTCCGAAGG-AGT--GGGTCACTCGGCGTAAGGTTGGG-TGGCAAAAG-GGGAACAACCCAGACCTG-GGTTAAGGCCCCAAAGTCCCGGCT-AAGTGCC---AACGAAAAGGCGTCTCCAGCCTTAGACAGCGGGAAGGTGGGCCCAGCAGCAGCCA-TCCTCTAAGGAGTGCGTAACAGCTCACCCGCC----GAGGCTGGAGGCCCTAAAGATTGGTCGGGGCTCAAGCCGGGCGCCGAGACCCAGGGTAGGGGG-GCGCTGTG-ATGGGGTAGAAGGT-GGGTCGTGAGATCCACTGGAGCAGATCCCGGCGGTAGTA-ACAGCG-AAGGGGGGTGAGAATCCCCCTCGCC-GGAAGGGC-AAGGGTTTCCC-GGCAACG-TTCGTCAGCCGGGAGTTAGCCGGTC--CTAAGGTAGGGCG--AAAGGGAAAGGGGTTAACATTCCCCTGCCCGGATTGGGGTAG-GGGAGAGCCGTACGGTGAGAAGAGGGC-GAAATCCCTAGTCCCCATGAAACGTACCTAGAACCGACACTGGTGCCCCTGGGTGAGAA-GCCCAAGGCGTCTGAGGGGTAACCCA-GGCTAGGGAACTCGGCAAATTAGCCCCGTAACTTCGGGAGAAGGGGTGCCATAGGTCGCAGTGACCAGAGGGACCTGACTGTTTAATAAAAACATAGGTCCCCGCTAGCCCG-AAAGGGTGTGTACGGGGGCTAAATCCTGGCCACTGGTGGTTGGTTAAATCCGGGTTCAAAAGCCCCACCGAAGGCCGGGGGTAACTCTGACCCTCTTAAGGTAGCCAAATGCCTTGCCGGGTAAGTTCCGGCGCGCATGAATGGATCAACGCGGTCCCTACTGTCCCAGCCTGGGGCCTCGTGAACGCCC--TGAGCCGGTGCACAGTCCGGCATCTCCCTACACCGAGAGAAGACCCCGTGGAGCTTCACCGCAGCCTGGCGTTGGGCGTTTATGCGTAGAGTAGGTGGGAGGGGTCG---AGACCCGAAAGTGAAACACCACCCAACAACGTCAGGTGGGCGGTTCGGCTGGGGCGGCACTCCCGCGAAAAGATAACACGGGAGCCCAAAGGTCGGCTCAGGCGGTACAGAACGCCGCCGTAGAGCG-CAAGGGCAAAAGCCGGCCTGACGTGACCCTTCCAAGTACGGGGTCACGACGCGAAAGCGGGGCCTAGCGAACGCTCGTGC--CCCCACACGTGGGGGCCGGGCATGACAGA--AAAGTTACCCCGGGGATAACAGGGTCGTCGCGGGCGAGAG-CTCACATCGACCCCGCGGTTTGCTACATCGATGTCGGCTCTTCCCACCCTGGAGGTGCAGCTGCCTCCAAGGGTAGGGCTGCCCGCCCGTTAAAGGGGAGCGTGAGCTGGGTTTAGACCGTCGCGAGACAGGTCGGACTCTAAGGGTAGGGAGTGCG-GACCGCTTGAGGGGAAGGAACCCCTAGTACGAGAGGAACAGGGTTCCGGGGCCTCCAGTTTACCGGTTGTCGGCA-ATGCCGGGCAGCCGCGCCCTGAGGGG-TAACCGCTGAAAGCATCTAAGCGGGAACCCCTCCCCTAA-AAGAGGCGGTGGGCCTTCCCCTAGAAGAGGGGGTTGATGGGGTGGGGATGTAAGGAGTTTAGTCCGCCACTCCCAA
Thermococcus_kodakarensis_Kod1                          GGTTGATCCTG-CCGGAGGCCACTGCTATGGGGGTCCGACTAAGCCATGCGAGTCGGCGGACGGCTCAGTAACACGTCGGTAACCTACCCTCGGGAGGGGGATAACCC--CGG-GAAACTGGGGCTAATCCCCCATAAGGTCCTCAGGCCGAAACGCCCGAGGATGGGCCGGCGGCCGATTA-GGTAGTTGGTGGGGTAACGGCCCACCAAGCCGAAGATCGGTACGGGCCATGAGAGTGG-GAGCCCGGAGATGGACACTGAGACACGGGTCCAGGCCCTACGGGGCGCAGCAGGCGCGAAACCTCCGCAATGCGGGCAACCGCGACGGGGGGACCCCCAGTGCTTTTCCGGAGTGTAAAAATAAGGGCTGGGCAAG-GCCGGTGGCAGCCGCCGCGGTAATACCGGCGGCCCGAGTGGTGGCCGCTATTATTGGGCCTAAAGCGTCCGTAGCCGGGCCCGTAAGTCCCTGGCGAAATCCCACGGCTCAACCGTGGGGCTTGCTGGGGATACTGCGG-GCCTTGGGACCGGGAGAGGCCGGGGGTACCCCTGG-GGTAGGGGTGAAATCCTATAATCCCAGGGGGACCGCCAGTGGCGAAGGCGCCCGGCTGGAACGGGTCCGACGGTGAGGGACGAAGGCCAGGGGAGCGAACCGGATTAGATACCCGGGTAGTCCTGGCTGTAAAGGATGCGGGCTAGGTGGTGCCGGAGGGAAGCCGTTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACTACAAGGGGTGGA-GCGTGCGGTTTAATTGGATTCAACGCCGGGAACCT-CACCGGGGGCGACGGCAG-GATGAAGGCCGCTGAAGGTCTGAGAGGAGGTGCATGGCCGCCGTCAGCTCGTACCGTGAGGCGTCCACTTAAGTGTGGTAACGAGCGAGACCCGCGCCCCCAGTTGCCAG--AGGCACTCTGGGGGGACCGCCGGCGA-TAAGCCG-GAGGAAGGAGCGGGCGACGGTAGGTCAGTATGCCCCGAAACCCCCGGGCTACACGCGCGCTACAATGGGCGGGACAATGGGATCCGACCCCGAAAGGGGAAGGGAATCCCCTAAACCCGCCCTCAGTTCGGATCGCGGGCTGCAACTCGCCCGCGTGAAGCTGGAATCCCTAGTACCCGCGTGTCATC-ATCGCGCGGCGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCACTCCACCCGAGCGGGCGAGCCTGGGCTCCGTGAGGGGGGAGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTACGGCTCGATCACCTGGATGGCTCGGCTCGGGGCGCCGACGAAGGGCGTGGCAAGCTGCGATAAGCCCCGGCGAGGCGC-AGGCAGCCGTCGAACCGGGGATGCCCGAATGGGACGCGGGGAATTGAAACATCTTAGTACCCGCAGGAAAAGAAAGCAAAA-GCGA-TGCCGTTAGTAGGGGCGACCGAAAGCGGCA-CAGGGCAAACAGCCGAAG-TCCGCTGGAACGGAGAGGGTGAAAGCCCCGTAGGCGTACCTGAGTACCGTCGGTCG---GATATCCGGCGGGAAGCTGGGAGGCATC-GGCTCCCAACCCTAAATACGTCCCGA-GACCGATAGCGAACT-AGTACCGTGAGGGAAAGCTGAAAAGCACCCCG-GGAGGGGGGTG-AAAAGAGCCTGAAACCAGGCGGCGATTGCACCGTCCGTCTTGGATCACGGGGCAGGGAGTTCA-CCCGAGCGGCGA-GGTTAAGAAGCCGCAGGGAAACCGACAGGTCCGCAAGTCGC-TCGGGTGAGACCCGAAGCCGGTCGATCTAGCCCGGGGCAGGGTGAAGTCCCT-CAACAGAGGGATGGAGGCCCG-CTAGGGGTGCTGACGTGCAATTCGCTCCCGTGACCCCGGGCTAGGGGTGAAAGGCCAATCGAGGCCGG-CGATAGCTGGTTCCCGCCGAATTATCCCCCAGGATAGCCCGGCCGGAGGTAGAG-CACTGATTGGGGGGCG-AAAGCCTCCGGCTCCCTGTCAAACTCCGAAGG-AGTAGGGGGGC---GGTGTAAGCC-GTC-ACCCGAGAG-GGGAACAACCCAGACCGG-GGTTAAGGCCCCAAAGTGCCGGCT-AAGTGTT--ACTCCAAAGGGTGTCCCTGGCCTTAGACAGCGGGGAGGTAGGCTTAGAAGCAGCCA-TCCTTTAAAGAGTGCGTAACAGCTCACCCGTC----GAGGTCAGGGGCCCCGAAAATGGAC-GGGGCTTAAGCCGGCCGCCGAGACCCCGGGTAGGCGG-GCGTGCCG-ATGGGGCGGAAGCC-GGGCCGTGAGGTCCGGTGGAGCGGATCCTGCCGGGAGTA-GCAGCA-TAGCCGGGTGAGAATCCCGGCCGCC-GTAGGGGC-CAGGGTTCCAC-GGCAATG-TTCGTCAGCCGTGGGTTAGTCGGTC--CTAACCCGACCCG--AAAGGGAAACGGGTTTATATTCCCGTACCCGCCTCGGGGTAG-GGGAGTGCCGTATGGCGAGAACCGGGT-GAAATCCCTGGGGCCCGTGAAACGTACCGAGAACCGACACTGGTGCCCCTGGGTGAGAA-GCCTAAGGCGTGTCGGGGGAAACCCA-GCCGAGGGAACTCGGCAAATTGGCCCCGTAACTTCGGGAGAAGGGGTGCCGCAGGTCGCAGTGACTAGGGGGGCCCGACTGTTTAGTAAAAACACAGGTCCCAGCTAGCCCG-AAAGGGTTTGTACTGGGGCCGACGCCTGCCCAGTGCCGGTATGTGAAGCCCGGGTACAAAAGCACCGGTAAACGGCGGGGGTAACTATAACCCTCTTAAGGTAGCGAAATTCCTTGTCGGTTAAATGCCGACCTGCATGAATGGCGTAACGAGGTCCCCACTGTCCCCGGCTGGGGCCCGGCGAAACCTC---TGCCAGGCGCATATGCCTGGGACCTCCGGTGGGAAGCGAAGACCCCATGGAGCTTTACTGCAGCCTGCCGTTGGCGGGGGGTGCGCAGCGTAGGCGGGAGGCGTCG---AGAGCCGCCCATGAGACACCGCCCGACAGCGGTAGGTGGGCAGTTTGGCTGGGGCGGCACACCCTCGAAAAGGTATCGAGGGTGCCCTAAGGTCGGCTCAGGCGGGTCAGGAATCCGCCGTAGAGTG-CAAGGGCAAAAGCCGGCCTGACTGGACCCGTAACAGAGGCGGGTCCAGCCGCGAAAGCGTGGCCTAGCGAACCCCTGTG---CCTCCCCGGTGGGGGCCAGGGATGACAGA--AAAGCTACCCTGGGGATAACAGAGTCGTCTCGGGCGAGAG-CCCATATCGACCCCGAGGCTTGCTACCTCGCTGTCGGCTCTTCCCATCCTGGCCCTGCAGCAGGGGCCAAGGGTGGGGGTGTTCACCCATTAAAGGGGAACGTGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGATGCTATCTACCGGAGGTGTT-GGCCGCCTGAGGGGAAGGCTCCCCCAGTACGAGAGGAACAGGGAGCCGCGGCCTCTGGTCTACCGGTTGTCGGCA-TAGCCGGGCAGCTACGCCGCAGCCGA-TAAGGCCTGAAAGCATCTAAGGCCGAAGCGGCCCCCGAA-AACAGGCGGCAGGGC-CCGGGAAGAAGACCCGGTTGATGGGGCGGGGATGTAACCCGTTCAGTCTGCCGCTCCCAA
Thermofilum_pendens_HRK_5                               GGTTGATCCTG-CCGGACCCGACCGCTATCGGGGTGGGGCTAACCCATGGAAGTCGGCGGACGGCTCAGTAGCACGTGGCTAACCTACCCTCGGGAGGGGGATAACCC--CGG-GAAACTGGGGATAAACCCCCATAATGGGTCCGCGCTGAAACGCCCGAGGATGGGGCTGCGCCCTATCA-GGTAGTTGGCGGGGTAACGGCCCGCCAAGCCGATAACGGGTGGGGGCCGTGAGAGCGG-GAGCCCCGAGATGGGCACTGAGACAAGGGCCCAGGCCCTACGGGGTGCACCAGGGGCGAAACTTCCGCAATGCGGGAAACCGTGACGGAGTCACCCCGAGTGCTTTTGCCCGGTCTAAAAATAAGCGGGGGGCAAG-CTTGGTGTCAGCCGCCGCGGTAATACCAACCCCGCGAGTGGTCGGGACGTTTATTGGGCCTAAAGCGTCCGTAGCCGGCCCGGTAAGTCCCTCCTTAAAGCCCACGGCTCAACCGTGGGAGCGG--AGGGATACTGCCG-GGCTAGGGGGCGGGAGAGGCCGGGGGTACTCCTGG-GGTAGGGGCGAAATCCTATAATCCCAGGAGGACCACCAGTGGCGAAGGCGCCCGGCTAGCACGCGCCCGACGGTGAGGGACGAAAGCTGGGGGAGCAAAGGGGATTAGATACCCCCGTAGTCCCAGCTGTAAACGATGCGGGCTAGGTGGTGCCGTAGGGAAGCCGTTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACCACAAGGGGTGAA-GCTTGCGGTTTAATTGGAGTCAACGCCGGAAACCT-TACCGGGGGCGACAGCAG-GATGAAGGCCGCTGACGACCTGAGAGGAGGTGCATGGCCGTCGCCGGCTCGTGCCGTGAGGTGTCCTGTTAAGTCAGGGAACGAGCGAGACCCCCGCCCCTAGTTGCTACTGGGGCACTCTAGGGGGACTGCCGGCGA-TAAGCCG-GAGGAAGGTGGGGGCTACGGCAGGTCAGTATGCCCCGAAACCCCCGGGCTACACGCGAGCTGCAATGGCGGGGACAGCGGGTTCCGACCCCGAAAGGGGGAGGTAATCCCTTAAACCCCGCCTCAGTAGGAATCGAGGGCTGCAACTCGCCCTCGTGAACGTGGAATCCCTAGTAACCGCGTGTCACC-AACGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCGCTCCACCCGAGGGAGCGAACCTGGGCCTCCCAAGGGGGGAGAAGTCGTAACAAGGTGGCCGTAGGGGAACCTGCGGCCGGATCACCTGGATGGCTCGGCTC-GGGCGCCGAGGAAGGCCGTGGCAAGCGGCGATACGCCCCGGGGAGCCGC-ATGCAGGCTTCGATCCGGGGATCGCCGAATGGGACCCCCCCAACGGAAACATCTTAGTAGGGGGAGGAGAAGAAACCAATT-GGGA-TCCCCTGAGTAG-GGCGACCGAAAGGGGGA-GAGCCCAAACAGCCGAAG-TCGGCTGGAACGTAGAGGGTGACAGCCCCGTAGGCTAACCTGAGTACCACGGCTTG---GTTTTGCCGTGGGAAGCTGGGGGGCACC-GACCTCCAAGGCTAAATACGTCCCGA-GACCGATAGCGAACTAAGTACCGTGAGGGAAAGCTGAAAAGCACCCCG-GAAGGGGGGTG-AAAAGAGCCTGAAACCGGGTGGCGATCGCGCCTTACGTCTAGAAACACGGGCCGGGGAGTTCA-CGGCTGTGGCGA-GCCTAAGAAGGCGTAGGGAAACCGACAAGCCCGTAAGTCAC-AGCCGTGAGACCAGAAACCGAGCGATCTAGGCCGGGGCAGGGTGAAGCCCGG-CGAAAGCCGGGTGGAGGCCCG--AAGGGGTTCTGACGTGCAATTCGTTCCCATGACCTCGGCCTAGGGGCAAAAGACCAATCAAGCTCGG-TGATAGCTGGTTCCCCCCGAAGCGGATCCCAGTCCGGCCCGCCCTGAGGTAGGG-CACTGATTGGGGACCG-AAAGGTCCCAGCTCCCTTTCAAACCCCGAAGG-AGACGGGTTCTGG-CGGATAAGCCGCCA-GGCCGAGAG-GGGAACAACCCAGACCGG-GGTTAAGGCCCCCAAGTGCCGGCTAAAGTGTC-AAGCCAGAAGGGTGTCCCCCGCCTTAGACAGCGGGGCCGTAGGCTTAGAAGCAGCCA-TCGGCTAAGAAGTGCGTAACAGCTTACCCGCC----GAGGCGGGGGGCCCCGAAGATTACC-GGGACT-AAGCCGGCCGCCGAGACCCCGGGTAGGGGG-GCGTCCAG-GTGGACTGGAAGCC-GGGCCGTGAGGTCCGGTGGAGAAAATCCCGGCGGTAGTA-AGAGCGCAAGAGGGGTGAGAATCCCCTCCGCC-GAAAGGGC-AAGGGTTCCTC-AGCAACG-GTCGTCGGCTGAGGGTTAGCCGGTC--CTAAGGCGGCCCG--AAAGGGAAAGGGGTTAATATTCCCCTGCCCGCCTCGGGATAG-GTGAGTGCCGTATGGCGAGAAGCGGGT-GAAACTCCTGGGGCCCGTGAAACGTACCGAGAACCGACACAGGTGCCCCTGGGTGAAAA-GCCCAAGGCGTGGCGGGGT-AACCCA-GGCTAGGGAACTCGGCAAATTAGCCCCGTAACTTCGGGAGAAGGGGTGCCGCAGGTCGCAGTGACAAGGGGGACCCGACTGTTTAATAAAAACATAGGTCCCCGCGAGCCCG-AAAGGGTGAGTACGGGGGCTGAATCCTGGCCACTGGCGGTACGTGAAACCCGGGTACAAAAGCGCCGCCGAAGGCCGGGAGTAACTCTGACTCTCTTAAGGTAGCCAAATGCCTTGCCGGGTAAGTTCCGGCGCGCATGAATGGATCAACGAGGTCCCCACTGTCCCAGCCTGGGACCCGCTGAACCCGC---AACCAGGTGCAGAGTCCTGGGAGTCCCGGTGGGGCGAGAAGACCCCGTGGAGCTTCACAGCAGCCTGGCGTTGGCTGCGGGTGCGTAGCGTAGGCGGGAG-CAATG---AGATGCGGCCATGAAACACCGCTCGACAGCGCCAGGTGGGCTGTTCGGCTGGGGCGGCACACCCCTGAGAAGGTATCAGGGGTGCCCAAAGCTCGGCTCAGGCGGGTCAGAACTCCGCCGTAGAGGG-CAAGGCCAAAAGCCGGGCTGACTGCGCCCTTAAACGCGTGGGGCGCAGGCGGGAAACCGGGGCCTAGCGAACGCTCGTGC--CCCCTTCGGTGGGGGCCGGGCATGACAGA--AAAGTTACCCCGGGAGTAACCGGCTCGTCGCGGGCGAGAG-TTCACATCGACCCCGCGGTTTGGTACCCAGACGTCGTCTCTTCCTAGCTTGGCCCTGCAGCAGGGGCCAAGAGTGGGGCTGCTCGCCCATTAAAAGGGAACGTGAGATGGGTTTAGACCGTCGCGAGACAGGTCGGACTCTACCTGCCGGGACCGTT-GGCCGCCTGAGGGGATGGTCCGCACAGTACGAGAGGAACTGCGGGCCGTGGCCTCTAGTGTACCGGTTGTCGGCA-CTGCCGGGCAGCCACGCCGCAAGGGG-TAACCGCTGAAGGCATCTAAGCGGGAAACCCACCCCGAG-ACGAGGCGGCAGGGC-ACCCGTAGAAGACGGGGTTGATGGGGTGGCGGTGTAAGGCGC-GAGCCGGCCACTCCCAA
Thermoplasma_volcanium_GSS1                             GGTCGATCCTG-CCGGCGGTCACTGCTATCAGGTTCCGACTAAGCCATGCAAGTCGGCGAACAGCTCAGTAACACGTGGATAATTTACCCTCAGGTGGGGTATAACCT--CGG-GAAACTGAGGCTAATCCCCCATAACGTTGTAATGATGAAACGCCTGAGGATAAGTCTGCGGCCTATCA-GGTAGTAGGTGGTGTAAAGGACCACCTAGCCTAAGACGGGTACGGGCCCTGAAAGGGG-GAGCCCGGAGATGGACTCTGAGACAACAGTCCAGGCCCTACGGGGCGCAGCAGGCGCGAAAACTGTGCAATGCGCGAAAGCGCGACACGGGGAACCTGAGTGCTTTTCTGATGCCTAAAAATAAGGGCTGGGCAAG-ACGGGTGCCAGCCGCCGCGGTAACACCCGCAGCTCGAGTGGTGATCACTTTTATTGAGTCTAAAGCGTCCGTAACCGGTCTTATAAATCTTCAGATAAATTCTCCCGCTTAACGGAAGAACTTCT-GAAGAGACTGTAA-GACTTGGGACCGGGTGAGGTTGAATGTACTTTCAG-GGTAGGGGTAAAATCCTGTAATCCTGAAAGGACGACCGGTGGCGAAAGCGTTCAACTAGAACGGATCCGACGGTGAGGGACGAAGGCTAGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCTAGCTGTAAACGCTGCCCACTTGGTGGTGCCGTAGCGAAGGTGTTAAGTGGGTCACTTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGAGCACCGCAACGGGAGGA-GCGTGCGGTTTAATTGGATTCAACGCCGGAAAACT-CACCGGGAGCGACCTTCG-GATGAGGGTCCCTGACGAATTGAGAGGTGGTGCATGGCCGTCGTCAGCTCGTACCGTAGGGCGTTCACTTAAGTGTGATAACGAGCAAGACCCCCATCTCTAATTGCTAAAGCTGCACTTTAGAGGGACCGCCAGCGC-TAAGCTG-GAGGAAGGAGGGGTCGACGGCAGGTCAGTACGCCCCGAATCTCCCGGGCTACACGCGCGCTACAAAGGACGGGACAATGAGTTGCAACCTCGAAAGGGGAAGCTAACCTCG-AAACCCGTTCGTAGTCAGGACTGAGGGCTGTAACTCGCCCTCACGAATGTGGATTCCGTAGTAATCGTAGGTCAAC-AGCCTACGGTGAATATGCCCCTGCTCCTTGCACACACCGCCCGTCAAACCATCCGAGCTGGCGAATCTGATGTCAGTGAGGAGGGTTAAGTCGTAACAAGGTATCCGTAGGGGAACCTGCGGATGGATCACCTGGATGGCTTGGTTC-GGGCGCCGAAGAAGGACGTGCCAAGCTGCGATATGCCTTGGGGAGGCGC-ATGGAGCCATAGATCCAAGGATTTCCGAATGGGACCCGGGGAATTGAAACATCTTAGTACCCGGAGGAAAAGAAATCAATC-GAGA-TACCGTTAGTAAAGGCGATCGAAAGCGGTA-AAAGGCAAACAGATGAA--TCTTCTGGAACAAAGAAGGTGATAGCCCTGTAATCGAACCAGAGTACCATGCGTCG---TTTTTCGCGTGGGAATGTGGGTGGCACT-AACATCCAACCTTAAATACGTCCCGA-ATCCGATAGCGAACTAAGTACCGTGAGGGAAAGCTGAAAAGTAACCCG-AAAGGGTGGTG-AAAAGAGCCTGAAACTAGGCAGAGATCCTATTGTCCGTGTTGAAGAACGGGCCAGGGAGTTCT-GACGGGTGGCAA-GGTTAAGAAGCCGTAGCGAAAGCGAT-TACCCGCAAGTCAC-TCGTGAGAGACCCGAAGCCGGTCGATCTACACCTGAGTAGGTTGAAGCTCAG-TGAAAGCTGGGTGGAGGACCG--AACCTATTCTGATGTGCAAATCGTTTGGATGACTTGGGTGTAGGGGTTAAAGGCCAATCTAGGCCGG-CAATAGCGGGTTCCCCCCGATACTACCCGCAGGTAGACCTCGACGGAGGTAGAGCGACCGATTGGCAGTCG-AAAGGCTGCGCCGACTTGTCAAACTCCGAAGGTGCTAGGGGGCA---GGGATAAGCTTTGC-TTCCGTGAT-GGAAACAACCAAGACGAG-GGTTAAGGTCCCTAAATTCTGGTT-AAGTGCA------CTAAATAGGTTTGTGGCCAAAGACAGCGGGGAGGTAGGCTTAGAAGCAGCCA-CCCTTTAAAGAGTGCGTAACAGCTCACTCGCC----GAGGTCACATGCCTAGAAGATGGAA-GGGGCTAAAACCAGATACCGAGACCTTCGGTAGGGGG-GCGTGCCA-TGTGGGCAGAAGTT-TCTTCGAGAGGAGGAATGGAGCGGATCCTGGTAAAAGTA-GCAGAG-AAGAACCGTGAGAATCGGTTCCGCC-GAAAGGGCTAAGGGTTCCTT-GGCAATG-TTCGTCAGCCGAGGGTTAGTCGATC--CTAAGGTCATACG--AAAGGGAAGCCGGTTAATATTCCGG----AGGTTCGAGGTAG-GGGAGAGTCGTATGACGAGAAGTTCGT-GAAATCCTTGGATCCCATGAAACGTACCAAGAACCGACACAGGTGCCCCTAGGTGAGAA-GCCTAAGGCGTTTTGGGAT-AATGGA-CGCGAGGGAAATCGGCAAAATAGCTCCGTATCTTCGGTATAAGGAGTGCCATAGGTCGCAGTGGCGAAGGGACTCCGACTGTTTACCACAAACACAGATCGCTGCTAGTCCG-TAAGGATGTGTATAGCGGTTGAAACCTGCCCAGTGCTGGTACCTGAAAGCCCCGCACAAAAGGGCCAGTAAACGGCGGGGGTAACTATGACCCTCTTAAGGTAGCGTAATACCTAGCCGCTTAATTGGCGGCTTGCATGAA-GGTTCAACGTGGGTCCCACTGTCCCCGCGTTCAGCCCAGTGAAATTGA--TGTACTGGTGCACAATCCAGTCTCTCCCACGTGAAAGCGAAGTCCCCGTGGAGCTTTACTGCAGCCTGTAGCTGATCCTGAATGCGTAGCGTAGGAAGGAGCCGTCG---AGAGGCGCCAATGAAACACTTCCCGACAACTATTGGTGGGCAGTTTGGGTGGGGCGCCACGCCCCTAACAATGTAACAGGGGCCCCCAAAGGTCAGCTCAGGAGGGTCAGAAATCCTCCGTAGAGTG-TAAAAGCAAAAGCTGGCTTGACTGTGTTGCAGACAACTAGCAACGCAGATGCGAAAGCAGGGTTTAGCGAACCACCCAGTT-CCTCCTTAGTGGGGGCGGGTGATAAGAGA--GAAGTTACCCCAGGGATAACTGAGTCGTCCTCGGCAAGAG-TACACATCGACCCGAGGGTTTGCTACTTCGATGTCGTCTGTTCCTATCCTGGTGCTGCATAAGGTGCCAAGGGTGGGGCTGTTCGCCCATTAAAAGGGATCCTGAGATGGGTTCACTACGTCGCGAGACAGTAGGGTTGCTTCTCCGTGGGAGTGCT-CGATGTCTGAGGGGAAGGGGCCTTTAGTACGAGAGGAACAAGGGCTCGTGACCTCTAGTTTACCGGTTGTCGGCA-TCGCCGGGTAGCCACGTCATACGCGGATAAGAGCTGAAGGCATCTAAGCTCGAAGCCGCCCCCGAA-AATAGACATCAGGCC-GCCTCTAAAAGAGAGGTTTGATAGGGCCGGGATGTAAGATTTTAAGTCCACGGCTACTAA
Thermoproteus_neutrophilus_V24Sta                       GGTTGATCCTG-CCGGACCCGACCGCTATCGGGGTAGGGCTAAGCCATGCGAGTCGGCGCACGGCTCAGTAACACGTGCCCAACCTACCCTCGGGAGGGGGACACCCC--CGG-GAAACTGGGGCCAATCCCCCATAAGGCCCCCTCCCCCAAACGCCCGAGGATGGGGGCACGGCCCATCA-GGTAGTTGGCGGGTTAAAGGCCCGCCAAGCCGAAGACGGGTAGGGGCGGTGAGAGCCGCGAGCCCCGAGATCGGCACTGAGACAAGGGCCGAGGCCCTACGGGGTGCAGCAGGCGCGAATACTCCGCAATGCGGGCAACCGCGACGGGGCTACCCCGAGTGCTTTTGCCCGGTCTAAAAATAAGCGGGGGGCAAG-TCTGGTGTCAGCCGCCGCGGTAATACCAGCTCCGCGAGTGGTCGGGGTGTTTACTGGGCTTAAAGCGCCCGTAGCCGGCCCGGCAAGTCGCTCCTGAAATCCCAGGGCCCAACCCTGGGGCGGGG-GGCGATACTGCCG-GGCTAGGGGGCGGGAGAGGCCGCCGGTACTCCGGG-GGTAGGGGCGAAATCCGTTAATCCCCGGAGGACCACCAGTGGCGAAAGCGGGCGGCCAGAACGCGCCCGACGGTGAGGGGCGAAAGCCGGGGGAGCAAAGGGGATTAGATACCCCTGTAGTCCCGGCCGTAAACGATGCGGGCTAGCTGGTGGCGAAGGGAAACCGTTAAGCCCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTTAAAGGAATTGGCGGGGGGGCACCACAAGGGGTGAA-GCTTGCGGCTTAATTGGAGTCAACGCCGGAAACCT-CACCCGGGGCGACAGCAG-GATGAAGGCCGCTAACGACCTGAGAGGAGGTGCATGGCCGTCGTCAGCTCGTGCCGTGAGGTGTCCGGTTAAGTCCGGCAACGAGCGAGACCCCCACCCCTAGTTGCTAGGGGGGCACACTAGGGGGACTGCCGGCG--TAAGCCG-GAGGAAGGAGGGGGCCACGGCAGGTCAGTATGCCGGGAGACCCCGGGGCTGCACGCGAGCTGCAATGGCGGGGACAGCGGGATCCGACCCCGAAAGGGGGAGGCAATCCCGTAAACCCCGCCCCAGTAGGGATCGAGGGCTGCAACTCGCCCTCGTGAACGTGGAATCCCTAGTAACCGCGTGTCACC-AACGCGCGGTGAATACGTCCCTGCCCCTTGCACACACCGCCCGTCGCACCACCCGAGGGAGCGAGCAGGGGGCTCCCAAGGGGGGTGAAGTCGTAACAAGGTAGCCGTAGGGGAACCTGCGGCTGGATCACCTGGATGGCTCGGCTC-GGGCGCCGAAGAAGGGCGTGGCAAGCTGCGATAAGCCCGGGGGAGCCGC-AGGCAGGCTTAGAACCCGGGATCCCCGAATGGGACGCGGGGAACGGAAACATCTTAGTACCCGCAGGAGGAGAAGCCAAAA-GGGA-TCCCCTGAGTAGGGGCGACCGAAAGGGGGA-GAGCCCAAACAGCCGAAG-TGGGCTGGAACGTAGAGGGTGATAGCCCCGTAGGCGAACCGGAGTACCACGGCTTA---GTTTTGCCGTGGGAATACGCCGGCCACT-GGCCGGCAAGGCTAAACACGTCCCGA-GTCCGATAGCGCACT-AGTACCGTGAGGGAAAGCTGAAAAGAACCCCG-GAAGGGGGGTG-AAAAGAGCCTGAAACCGGGCGGCTATCCGCCCTTACGTCTAGAAACACGGGCCGGGGAGTTCA-CGGCCGTGGCGA-GCCTAAGGAGGCGTAGGGAAACCGAC-AGCCCGCAAGTCAC-GGCCGTGAGACCAGAAACCGGGCGATCTAGCCCTGGGCAGGGCGAAGCGGGG-CGAAAGCCCCGTGGAGGCCCG--AAGGGGTTCTGATGTGCAAATCGTTCCCATGACCTGGGGCTAGGGGCAAAAGACCAATCAAGCCCGG-TGATAGCTGGTTCCCCCCGAAGCTGGTCCCAGCCAGGCCTCCCCAGAGGTAGAG-TACTGATCGGGAGCCG-AAAGGCTCCGGCCCCCGGTCAAACTCCGAAGG-AGGCGGGGGCGGT-GGGGTAAGCCTCCG-CTCCGAGAC-GGGAACAACCGAGACCGG-GGTTAAGGCCCCCAAGTGCGGGCT-TAGTGTC-AATCTCAAAGGGCGTCCCCCGCCCAAGACAGCGGGGCCGTGGGCCTAACAGCAGCCA-TCGGCTAAGCAACGCGTAACAGCGGACCCGCC----GAGGCGGGGGGCCCCGAAGATGTACAGGGACT-AAGCCCGCCGCCGAGACCCCGGGTAGGGGG-GCGCGGCC-GTGGGGCAGAAGCC-GGGCCGTGAGGTCCGGTGGAGAAGATCCCGGCGGTAGTA-GCAGCG-AAGAGGGGTGAGAAGCCCCTCCGCCGGAAAGGAC-CAGGGTTTCCT-GGCAACT-TCAATAGGCCAGGAGTTAGCCGGTC--CTAAGGCGGGGCG--AAAGGGAAACGGGTTAATATTCCCGTGCCCGCCTCGGGATAG-GGGAGTGCCGTATGGCGAGAACCGGCC-GAAAATCCTGGGGCCCGTGAAACGTACCGAGAACCGACGCAGGTGCTCCTGGGTGAGAA-GCCCAAGGCGGCTCGGGTG-ACCCCG-GGCCAGGGAACTCGGCAAATTGGCCCCGTAACTTCGGGAGAAGGGGTGCCGCAGGTCGCAGTGACAAGGGGGACCTGACTGTTTAACAAAAACATAGGTCCCCGCGAGCCCG-TAAGGGTGTGTACGGGGGCTGAATCCTGGCCACTGGCGGTACGTGAACCCCGGTTACAAAAGCGCCGCTGAAGGCCGGGGGTAACTCTGACCCTCTTAAGGTAGCCAAATGCCTTGCCGGGTAAGTTCCGGCGTGCATGAATGGATCAACGAGGTCCCCACTGTCCCGGCCCGGGGCCCGGCGAACCCAC---CTCCAGGTGCACAGTCCTGGGACCCCCGACGGGGCGAGAAGTCCCTATGGAGCTTCACAGCAGCCTGTCGTTGGCGGGGGGTGCAGAGCGTAGGTGGGAG-CGATG---AGATGCGGTCCTGGAACACCACCCGACAGCGGCAGGCGGGCTGTTCGGCTGGGGCGGCACACCCCTGAAAAGATATCGGGGGTGCCCAAAGCTCGGCTCAGGCGGGTCAGAAATCCGCCGTAGAGTG-TAAGGGCAAAAGCCGGGCTGACTGGGCCCTTGAACACAAGGGGCCCAGGCGGGAAACCGGGGCCTAGAGAACGCTCGTGC--CCCCACCAGTGGGGGCCGGGCATGACAGA--AAAGTTACCCTAGGAATAACCGGCTCGTCGCGGGTGAGAG-TCCCCATCGACCCCGCGGTTTGGTACCCAGACGTCGTCTCTTCCCATCCTGGCGGTGCAGCAGCCGCCAAGGGTGGGGCTGCCCGCCCATTAAAGGGGAACGTGAGATGGGTTCAGACCGTCGCGAGACAGGTCGGTCTCTACCTGTCGGGGGCGTT-GGCCGCCTGAGGGGAAGGTGCCCTCAGTACGAGAGGAACGGGGCGCCGCGGCCTCTAGTGTACCGGTTGTCGGCA-CTGCCGGGCAGCCACGCCGTGGGGGA-TAACCGCTGAAAGCATCTAAGCGGGAAGCCCTCCCCGAG-ACGAGGCGGCAGGGC-TCCCGTAGAAGACGGGGTTGATGGGGGGGCGGTGTAAGGGGG-GAGCCGGCCCCTCCCAA
Thermotoga_maritima                                     GTTTGATCCTGGCTCAGGGTGAACGCTGGCGGCGTGC--CTAACACATGCAAGTCGGCGGACGGGTGAGTAACACGTGGGTAACCTGCCCTCCGGAGGGGGATAACCA--GGG-GAAACCCTGGTTAATACCCCATATTG----GTGGAGGAAACGCCGGAGGAGGGGCCCGCGGCCCATCA-GGTAGTTGGTGGGGTAACGGCCCACCAAGCCGACGACGGGTAGCCGGCCTGAGAGGGT-GGTCGGCCACAGGGGCACTGAGACACGGGCCCCACT-CTACGGGAGGCAGCAGTGGGGAATCTTGGACAATGGGGGAAACCCTGATCCAGCGACGCCGCGTGCCGCTGTG-GCGGGGGAAGAAAGCCCCGGCTAAC--TACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTACCCGGATTTACTGGGCGTAAAGGGGGCGTAGGCGGCCTGGTGTGTCGGATGTGAAATCCCACGGCTCAACCGTGGGGCTGCA-TCCGAAACTACCA-GGCTTGGGGGCGGTAGAGGGAGACGGAACTGCCGG-TGTAGGGGTGAAATCCGTAGATATCGGCAGGAACGCCGGTGGGGAAGCCGGTCTCCTGGGCCGACCCCGACGCTGAGGCCCGAAAGCCAGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCTGGCTGTAAACGATGCCCACTAGGTGGTGCTGAAGCTAACGCGTTAAGTGGGCCGCCTGGGGAGTACGCCCGCAAGGGTGAAACTCAAAGGAATTGACGGGGGCCCGC-ACAAGCGGTGGA-GCGTGTGGTTTAATTGGATGCTAAGCCAAGAACCT-TACCAGGGCTTGACATGCCGGTGGTACCTAGGGGTAGGGACACAGGTGGTGCACGGCCGTCGTCAGCTCGTGCCGTGAGGTGTTGGGTTAAGTCCCGCAACGAGCGCAACCCCTGCCCCTAGTTGCCAGCCGGGCACTCTAGGGGGACTGCCGGCGA-CGAGCCG-GAGGAAGGAGGGGATGACGTCAGGTACTCGTGCCCCTTATGCCCTGGGCGACACACGCGCTACAATGGGCGGTACAATGGGTTGCGACCCCGCGAGGGGGAGCCAATCCC-CAAAGCCGCCCTCAGTTCGGATCGCAGGCTGCAACCCGCCTGCGTGAAGCCGGAATCGCTAGTAATCGCGGATCAGCCATGCCGCGGTGAATACGTTCCCGGGCCTTGTACACACCGCCCGTCACGCCACCCGAGTCGGCGAGGGAGAACCTGGCGAGGGGGGCGAAGTCGTAACAAGGTAGCCGTACCGGAAGGTGCGGCTGGATCACCTGGATGCCTTGGCGGCGGGAGGCGATGAAGGGCGTGGCAAGCTGCGATAAGCCCGGGGGAGCCGC-AAGCAGGCGTTGATCCCGGGATTCCCGAATGGGACCGGGGGAAGTGAAACATCTCAGTACCCCGAGGAAAAGAAATCAACC-GAGA-TTCCCCTAGTAGCGGCGAGCGAACGGGGAG-GAGCCCAAACAGCCG-AA-CCACCTGGGACGGAGAGGGTGACAGCCCCGTAGGCGAACCCGAGTACCACGGGACACGTGGAATCCCGTGGGAAGCTGGGGGG-ACC-ACCCTCCAAGGCTAAATACTACCCGCCGTCCGATAGCGCACC-AGTACCGTGAGGGAAAGGTGAAAAGCACCCCGGA-AGGGGAGTGAAAGAGGACCTGAAACCGCGTGCCTATGACGGCGTGCCTTTTGATTAATGAGCCCGCGAGTTG-CCGTCGGTGGCGA-GGTTAAGTAGCCGTAGCGAAAGCGAG-TCCGAACAAGTCACCGGCGGCA-GACCCGAAGCCGGGTGAGCTACCCCTGGGCAGGGTGAAGGTGGG-TTAAAACCCACTGGAGGCCCG---AACCGGTGGACAGTGAAAAGTCCTCGGATGACCTGGGGGTAGGAGTGAAAAGCTAACCGAACCCGG-TGATAGCTGGTTCTCCCCGAAATGCATTGAGGTGCAGCCTCGGG-CGGGTAGAGC-ACTGATGGGGGGTTTCCT------CCGAACCCCGTCAAACTCCGAAGGGAGTGAGCCCGCGG-GGGATAAGCTCCGC-GGACGAGAG-GGGAACAACCCAGACCGCCGGCTAAGGGCCCGAAGAGGTGGCT-AAGTG-------GTAAAGGATGTGGAGCGCCTAAGACAGCTGGGATGTTGGCTTAGAAGCAGCCA-TCATTTAAAGAGTGCGTAACAGCTCACCAGCC----GAGGCGCTCTGCACCGAAAATGTAACGGGGCTCAAGCCACCCCCCGAAGCCGCGGGTAGGGGA-GCTTTCCGCTGTAGGGTGAAGGCGGACCCGCGAGGGCCGCTGGAGAGAATGCGGGCATGAGTACGCGA-A--AGGAGGGTGAGAATCCCTCCCCCC-GTAAGCCC-AAGGGTACCTG-GGGAAGG-TTCGTCCGCCCAGGGTTAGCCGGGACCCTAAGGTGAACCGCCGAAGGGAAGCCGGTTAATATTCCGGCGCCCGCAGGAGGGTAG-GGTAAATCCGC--GAGCCTGAGCCGT--GATACCCCACACTGCCGAGAAACGTTCCGCAAACCGACACAGGTGGGCGGGCT-GAGAA-GGCTCAGGGGA-GCGGGTTAACCCTC--GCCAAGGAACTCGGCAAATTGGCCCCGTAACTTCGGGAGAAGGGGTGCCGGCGGTCGCAGTGACAAGGCCCTGGCGACTGTTTACCAAAAACACAGGTCTCTGCTAACTCGAAAAGAGGAAGTATAGGGACTGACGCCTGCCCAGTGCCGGAAGGTTAAGGGGAGGGGTGAAAGCCCCGGTAAACGGCGGCCGTAACTATAACGGTCCTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCTGCATGAATGGCGTAACGACTGGGGCACTGTCTCGGCGGGGGGCCCGGCGAAATTTC--AGTCTGGGTGAAGATGCCCAGTACCCGCGGCTAGACGGAAAGACCCCGTGGAGCTTTACTGCAGCCTGGTATTGGTGCATCGTGTATAGCATAGGTGGGAGGCTGTG---AGAGCCGCCAGTGGAATACCACCCGACAGTGCCAGGTGGGCAGTTTGACTGGGGCGGT-CACCTCCTAAAAGGTAACGGAGGTGTGCAAAGGTCGGCTCAGGTGGGTTGGAAATCCACCGCAGAGTG-CAAGGGCATAAGCCGGCCTGACTGCGAGGCCGA---CAGGCCGAGCAGGGGGGAAACCCGGCCCTAGTGACCCGGCGGTC---CCGTGTGGAAGGGCCGTCGATCAACGGATAAAAGTTACCCCGGGGATAACAGGCTGGTCCCGCCCGAGAG-TTCACATCGACGGCGGGGTTCGGCACCTCGATGTCGGCTCATCCCATCCTGGGGCTGAAGCAGGTCCCAAGGGTTGGGCTGTTCGCCCATTAAAGGGGTACGTGAGCTGGGTTCAGACCGTCGTGAGACAGGTCGGTCCCTATCTGCCGCGGGCGTA-GGAGGCTTGAGGGGG-GTCCTCCCTTGTACGAGAGGACCGGGAGGAGGGGGCCTCTGGTGTACCGGCTGTCGGCATACGCCGGGTAGCTACGCCCCTAAGCGATAACCGCTGAAAGCATCTAAGCGGGAAGCGCGCCCCAAG-ATTAGGCCTCAAGGCCGGTCCGAGAAGAGGACCTTGATAGGCCGGGGGTGTAA-GCGTTGAGCCCACCGGTACTAA
Thermus_thermophilus                                    GTTTGATCCTGGCTCAGGGTGAACGCTGGCGGCGTGC--CTAAGACATGCAAGTCGGCGGACGGGTGAGTAACGCGTGGGTGACCTACCCGGAAGAGGGGGACAACCC--GGG-GAAACTCGGGCTAATCCCCCATGTTGGGGTGTGTCCAAAGCGCTTCCGGATGGGCCCGCGTCCCATCA-GCTAGTTGGTGGGGTAATGGCCCACCAAGGCGACGACGGGTAGCCGGTCTGAGAGGAT-GGCCGGCCACAGGGGCACTGAGACACGGGCCCCACTCCTACGGGAGGCAGCAGTTAGGAATCTTCCGCAATGGGCGCAAGCCTGACGGAGCGACGCCGCTTGCTCCTGA--ACCCGGGAAAT-AGCGCCGGCCAAC--TCCGTGCCAGCAGCCGCGGTAATACGGAGGGCGCGAGCGTTACCCGGATTCACTGGGCGTAAAGGGCGTGTAGGCGGCCTGGGGCGTCCCATGTGAAAGACCACGGCTCAACCGTGGGGGAGCG-TGGGATACGCTCA-GGCTAGACGGTGGGAGAGGGTGGTGGAATTCCCGG-AGTAGCGGTGAAATGCGCAGATACCGGGAGGAACGCCGATGGCGAAGGCAGCCACCTGGTCCACCCGTGACGCTGAGGCGCGAAAGCGTGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCACGCCCTAAACGATGCGCGCTAGGTCGGGCCGAAGCTAACGCGTTAAGCGCGCCGCCTGGGGAGTACGGCCGCAAGGCTGAAACTCAAAGGAATTGACGGGGGCCCGC-ACAAGCGGTGGA-GCATGTGGTTTAATTCGAAGCAACGCGAAGAACCT-TACCAGGCCTTGACATGCTAG-GGAACCCAGCCTGGGGTGCACAGGTGCTGCATGGCCGTCGTCAGCTCGTGCCGTGAGGTGTTGGGTTAAGTCCCGCAACGAGCGCAACCCCCGCCGTTAGTTGCCAGCCGGGCACTCTAACGGGACTGCCCGCG---AAAGCGGGAGGAAGGAGGGGACGACGTCTGGTCAGCATGGCCCTTACGGCCTGGGCGACACACGTGCTACAATGCCCACTACAAAGCGATGCCACCCGGCAACGGGGAGCTAATCGCAAAAAGGTGGGCCCAGTTCGGATTGGGGTCTGCAACCCGACCCCATGAAGCCGGAATCGCTAGTAATCGCGGATCAGCCATGCCGCGGTGAATACGTTCCCGGGCCTTGTACACACCGCCCGTCACGCCATGGGAGCGGGCGAGGGTAGGGCCCGTGACTGGGGCGAAGTCGTAACAAGGTAGCTGTACCGGAAGGTGCGG-----------GGATGCCTCGGCACCC-GAGCCGATGAAGGACGTGGCTACCTGCGATAAGCCAGGGGGAGCCGG-TAGCGGGCGTGGATCCCTGGATGTCCGAATGGGACCTGGGGAACTGAAACATCTCAGTACCCAGAGGAGAGGAAAGAGAAA-TCGA-CTCCCTGAGTAGCGGCGAGCGAAAGGGGAC-CAGCCTAAACAGCCGAAG-CTGT-TGGGACAGAGAGGGTGAAAGCCCCGTAGGCGAACCCGAGTACCCCGTGGTTCGTGGAGCCATGGGGGAATCTGGGCGG-ACC-ACCGCCTAAGGCTAAGTACTCC-GGGTGACCGATAGCGCACC-AGTACCGTGAGGGAAAGGTGAAAAGAACCCCGGG-AGGGGAGTGAAATAGAGCCTGAAACCGTGGGCTTATTGTGGCGTGCCTATTGAAGCATGAGCCGGCGACTCA-CGGTCGTGGGCGA-GCTTAAGGAGGCGTAGGGAAACCGAG-TCCGAACAAGTCCGCGGCCGTG-GACCCGAAACCGGGCGAGCTAGCCCTGGCCAGGGTGAAGCTGGG-GTGAGACCCAGTGGAGGCCCG---AACCGGTGGGGGATGCAAACCCCTCGGATGAGCTGGGGCTAGGAGTGAAAAGCTAACCGAGCCCGG-AGATAGCTGGTTCTCCCCGAAATGACTTTAGGGTCAGCCTCAGG-CGCGTAGAGC-ACTGATAGGGGCCC-ACCAGCCTACCAAACCCTGTCAAACTCCGAAGGGAGTGAGGGCGCGA-GCGATAACGTCCGC-GTCCGAGCGCGGGAACAACCGAGACCGCCAGCTAAGGCCCCCAAGTCTGGGCT-AAGTG-------GTAAAGGATGTGGCGCCGCGAAGACAGCCAGGAGGTTGGCTTAGAAGCAGCCA-TCCTTTAAAGAGTGCGTAATAGCTCACTGGTC----GAGTGGCGCCGCGCCGAAAATG-ATCGGGGCTCAAGCCCAGCGCCGAAGCTGCGGGTAGGGGA-GCGTTCCCGATGCCGATGAAGGCCGACCCGCGAGGGCGGCTGGAGCGAATGCCGGCATGAGTA-ACGATA--AAGAGGGTGAGAATCCCTCTCGCC-GTAAGCCC-AAGGGTTCCTA-CGCAATG-GTCGTCAGCGTAGGGTTAGGCGGGA-CCTAAGGTGAAGCGCCGAAGGGCAGCCGGTTAATATTCCGGCCCTCGCTCTAGGCTAGGGGCAAATCCGCAAAGCTCTGCGTGGT--GGGAAGCCAGGGAGCCAAGAAACGTACCGCAAACCGACACAGGTGGGCGGGTGCAAGAG-CACTCAGGCGC-GCGGGAGAACCCTC--GCCAAGGAACTCTGCAAGTTGGCCCCGTAACTTCGGGAGAAGGGGTGCTGGGAGCCGCAGTGAACAGGCTCTGGCGACTGTTTACCAAAAACACAGCTCTCTGCGAACTCG-TAAGAGGAGGTATAGGGAGCGACGCTTGCCCGGTGCCGGAAGGTCAAGGGGAGGGGTGCAAGCCCCGGTGAACGGCGGCCGTAACTATAACGGTCCTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCTGCACGAAAAGCGTAACGACCGGAGCGCTGTCTCGGCGAGGGACCCGGTGAAATTGA--ACTGGCCGTGAAGATGCGGCCTACCCGTGGCAGGACGAAAAGACCCCGTGGAGCTTTACTGCAGCCTGGTGTTGGTCGCGCCTGCGTAGGATAGGTGGGAGCCTGTG---AGAGGCGCCGGTGAAATACCACCCGACAGCGCTTGGCGGGCAGTTTGACTGGGGCGGT-CGCCTCCTAAAAGGTAACGGAGGCGCCCAAAGGTCCCCTCAGGCGGGACGGAAATCCGCCGGAGAGCG-CAAGGGTAGAAGGGGGCCTGACTGCGAGGCCTG---CAAGCCGAGCAGGGGCGAAAGCCGGGCCTAGTGAACCGGTGGTC---CCGTGTGGAAGGGCCATCGATCAACGGATAAAAGTTACCCCGGGGATAACAGGCTGATCTCCCCCGAGCG-TCCACAGCGGCGGGGAGGTTTGGCACCTCGATGTCGGCTCGTCGCATCCTGGGGCTGAAGAAGGTCCCAAGGGTTGGGCTGTTCGCCCATTAAAGCGGCACGCGAGCTGGGTTCAGAACGTCGTGAGACAGTTCGGTCTCTATCCGCCACGGGCGCA-GGAGGCTTGAGGGGG-GCTCTTCCTAGTACGAGAGGACCGGAAGGGACGCACCTCTGGTTTCCCAGCTGTCGGCATAAGCTGGGTAGCCATGTGCGGAAGGGATAACCGCTGAAAGCATCTAAGCGGGAAGCCCGCCCCAAG-ATGAGGCCTCAAGGACCCGGGAAGACGACCCGGTGGATGGGCCGGGGGTGTAAGGCGTTGAGCCGACCGGTCCCAA
Uncultured_crenarchaeote_74A4                           GGTTGATCCTG-CCGGACCTGACTGCTATCGGATTGATACTAAGCCATGCGAGTCGGCATACGGCTCAGTAACGCGTAGTCAACCTAACCTATGGACGGGAATAACCT--CGG-GAAACTGAGAATAATGCCCGATAATGGTTTGTGTTCCAAACGCCATAGGATGGGACTGCGGCCTATCA-GTTTGTTGGTGAGGTAATGGCCCACCAAGACTATTACAGGTACGGGCTCTGAGAGGAG-TAGCCCGGAGATGGGTACTGAGACACGGACCCAGGCCCTATGGGGCGCAGCAGGCGAGAAAACTTTGCAATGTGCGAAAGCACGACAAGGTTAATCCGAGTGCTTTTGTTAGTCCTAGAAATAAGGGGTGGGCAAGTTCTGGTGTCAGCCGCCGCGGTAAAACCAGCACCTCAAGTGGTCAGGATGATTATTGGGCCTAAAGCATCCGTAGCCGGCTCTGTAAGTTTTCGGTTAAATCTGTACGCTTAACGTACAGGCTGCC-GGGAATACTGCAG-AGCTAGGGAGTGGGAGAGGTAGACGGTACTCGGTA-GGAAGTGGTAAAATGCTTTGATCTATCGATGACCACCTGTGGCGAAGGCGGTCTACCAGAACACGTCCGACGGTGAGGGATGAAAGCTGGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCCAGCTGTAAACTATGCAAACTCAGTGGTGCTGCAGGGAAGCCGTTAAGTTTGCCGCCTGGGAAGTACGTACGCAAGTATGAAACTTAAAGGAATTGGCGGGGGAGCACCACAAGGGGTGAA-GCCTGCGGTTCAATTGGAGTCAACGCCAGAAATCT-TACCCGGAGAGACAGCAG-AATGAAGGTCGCTGAAGACTTGAGAGGTGGTGCATGGCCGTCGCCAGCTCGTGCCGTGAGATGTCCTGTTAAGTCAGGTAACGAGCGAGATCCCTGCCTCTAGTTGCCAGTGGGGCGAATTAGCGGGACCGCCGCAGT-TAATGCG-GAGGAAGGAAGGGGCCACGGCAGGTCAGTATGCCCCGAAACTCTGGGGCCACACGCGGGCTGCAATGGTAGCGACAATTGGTTTCGAATCCGAAAGGATGAGGTAATCCAC-AAACGCTACCACAGTTATGACTGAGGGCTGCAACTCGCCCTCACGAATATGGAATCCCTAGTAACTGCGTGTCATT-ATCGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCGTTTCATTGAAGTGAGCGAACTTGAGGTTCGTGACAAGGGAAAAGTCGTAACAAGGTGACCGTAGGGGAA-CTGCGGTCGGATCACCTGGATTGCTAGGCTT-GAGAAGAGATGAAGGACGTGGCAAGCTGCGATAAGCTCGGGGTAGGCGC-ACGCATCCTATGATCCCGAGATGTCCGAATGAGACCGTGGGAATTGAAGCATCTTAGTACCACGAGGAAAAGAAATCAATA-GAGA-TTTCCCAAGTAGAGGCGATCGAAAAGGAAA-GAGCCCAAACAGCTGAAA-TGATCTGGAAAATAGAGGGTGATACCCCCGTAAGCGAACCCGAGTAGTTGTCCTTG---GTAGTGGGCAATGAATATGGGTGAAAGT-AGCATCCGAGGCTAAATATTTCTCAA-GACCGATAGTGGACT-AGTACCGTGAGGGAAAGCTGAAAAGTACCCCG-GAAGGGGGGCG-AAAAGTGCATGAAACCTATTACTTATCACGCGTTCCGTCTCGAAACACGGGCCAAGGAGCTAA-CCGTCATGGCAA-GCTTAAGCAGGCGAAGGGAAACCGAG-CTCTCGCAAGTCAT-GGCGGCTAGGCTAGAAGCCAGTCGATCTATTCCTGAGCTAGATGAAGGGGGG-CGAAAGCCCCCTGGAGGTCTT--AAGACGTTCTGACGTGCAAATCGTTGTTGTGACTTGGGAATAGGGGTCAAAAACCAATCTAGACTGG-CGCTCGCTAGTTCCAACCGAAGCGTCTCGCAGGGCGTGGTTTGTGGAGGTAGAG-CACTGATAGAGGGGAG-AAATCCCTCACCCTCCATTCAAACTCCGAAGC-ACACGGGCTCATGTGGCGTAAGGCTCAT-GGCCGAAAG-GGGTTTAACCCAGACTGA-AGTTAAGGTCCCCAAATTTTTGCT-AAGTGTC--AAGCGAAAGAGCGTGTTCTCGCCAAGACAGCAGGGAGGTAAGCTCAGAAGCAGCTA-TCCTTTAAAAAATGTGTAACAACTTACCTGCC----GAGGGGGGATGCCTCAAAAACGGAC-GGGGCTAAAGCAAAATACCGATACTTTAGGTAGGTTG-GCGTAGTG-ATTGGGTCGAAGCA-GGGCGATGACGTCCTGTGGAGCAGATCTTGGCGGCAGTA-ACAGCA-TAGTATTGTGAGAAACAATACCACC-GCAAGCGC-AAGGGTTTCCA-GGCAATGCGTTATCAGCCTGGAGGTAGTCGATC--CTAAGATGTGCCG--AATGGGAAATCAGTTAATATTCTGATACCCGCTTCCGGATAA-GGGAGTGTCGTATGACGAGAACCTTTC-CGAATTCCAGGAGACCATGAAACGTACCCAGAACCGACACAGGTGCGC-TGGCTTAGAA-AGCTAAGGTGCTACGGGTATACCGTATGGCGAGGGAATTCGGCAAATTAGTCCTGTAGCTTAGGTATAAGGGATGCCGCAGGTTGCAATAACAAGGGGGTTCCGACTGTTTAATAAAAACACAGGCGACTGCTAGTCCG-AAAGGATTTGTATAGTCGCTGAATCCTGGCCGGTGCCGGTACCTAAAACTTGGGTTCAAAAGGGCCGGTTAACGCCGGGAGTAACTCTGACTCTCTTAAGGTAGCCAAATGCCTTGTCGGGTAAGTTCCGACGCGCATGAATGGAACAACGAGAGCCCCACTGTCCCCGCCTACAACCCGGTGAAGCCACATAAGGTGGACGAACAGTCCATCAACTTCCATCGGGGAGAGAAGACCCCGTGGAGTTTTACTGCAGCTTGTGCTTGGTAAGAATTGCACAGGGTATCTGGGAGCTATGCTTAAGAAGCAACGATGTAACACCAGACGACACGTGCAGGTAGGCAGTTCGGCTGGGGCGGCACCCCTTTGAAAAGATATCAAAGGGGCCCAAAGTTGAGTTCAAACGGGGCAGAAATCCGTTGAAGAGGG-CAAAGCCAAAAACTCGACTGAATGGATTTCCAAACGCACGGAATTCATAGACGAAAGTCTGGCTTAGCGATCCTTCGTGT--GCCCACTATTGGGGCCCGGAGGTGACAGA--AAAATTACCCCAGGGATAACAGGCTCGTCGCGGGCGAGAG-CTCCTATCGACCCCGCGGTTTGGTACCTCGATGTCGGCTTTTCCTATCCTGGTCCTGCAGCAGGGGCCAAGGGTGAGGCTGCTCGCCTATTAAAAGGGAACATGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGTCTCTGCCTGATGGAAGCGT--GAATAACTGAGGGGAACTTGCTCCTAGTACGAGAGGAACAGAGCAGGGTGGCCACTGGTTTACCGGTTGTCGGCA--GGCCGGGCAGCTAAGCCGTTTAGGC-TAAGTGCTGAAAGCATCTAAGCACGAATCCTATCCCGAG-ACAAGTTATTAAGGTCGGCAGTCCAATACTGCGTTGATAGGAAGGTGGTGTAAG-TGGTGAGCCAGCCTTTACTAA
'Uncultured marine crenarchaeote KM3-34-D9'             GGTTGATCCTG-CCGGACCTGACTGCTATCGGATTGATACTAAGCCATGCGAGTCGGCAGACGGCTCAGTAACGCGTAGTCAACCTACCCTATGGACGGGAATAATCT--CGG-GAAACTGAGCATAATACCCGGCGATGGTTGGTGGTTAAAACGCCGTAGGATGGGACTGCGACCTATCA-GCTTGTTGGTGAGGTAAAGGCCCACCAAGGCGATTACAGGTACGGGCTCTGAGAGGAG-AAGCCCGGAGATGGGTACTGAGACACGGACCCAGGCCCTATGGGGCGCAGCAGGCGAGAAAACTTTGCAATGTGCGAAAGCACGACAAGGTTAATCCGAGTGCTTTTGCCAGTTCTAAAAATAAGGGGTGGGCAAGTTCTGGTGTCAGCCGCCGCGGTAAAACCAGCACCTCAAGTGGTCAGGAGGATTATTGGGCCTAAAGCATCCGTAGCTTGCTCTGTAAGTTTTCGGTTAAATCTATATGCTCAACGTATAGGCTGCC-GAAAATACTGCAG-TGCTAGGAAGTGGGAGAGGTAGACGGTACTTGATA-GGAAGGGGTAAAATCCTTTGATCTATCGATGACCACCTGTGGCGAAGGCGGTCTACCAGAACACGTTCGACGGTGAGGGATGAAAGCTGGGGGAGCAAACCGGATTAGATACCCGGGTAGTCCCAGCTGTAAACGATGCAGACTCGATGGTGTCGCAGGGAAGCCGTTAAGTCTGCCGCCTGGGAAGTACGTACGCAAGTATGAAACTTAAAGGAATTGGCGGGGGAGCACCACAAGGGGTGAA-GCCTGCGGTTCAATTGGAGTCAACGCCAGAAATCT-TACCCGGAGAGACAGCAG-AATGAAGGTCGCTGAAGACTTGAGAGGTGGTGCATGGCCGTCGTCAGCTCGTGCCGTGAGATGTCCTGTTAAGTCAGGTAACGAGCGAGATCCCTACCACTAGTTGCTAGTGGAGCGAATTAGTGGGACCGCTGTAG--TAATATG-GAGGAAGGAAGGGGCTACGGCAGGTCAGTATGCCCCGAAACTCTGGGGCCACACGCGGGCTGCAATGGTAGTGACAATGGGCGCCTAACTCGAAAGAGTGCGGCAATCCTT-AAACGCTACCACAGTTATGACTGAGGGCTGTAACTCGCCCTCACGAATATGGAATCCCTAGTAACTGCGTGTCATT-ATCGCGCGGTGAATACGTCCCTGCTCCTTGCACACACCGCCCGTCGTTTCATCGAAGTTTGCGAACTTGGGGTAAGCAACGAGGGAAAAGTCGTAACAAGGTGACCGTAGGGGAACCTGCGGTCGGATCACCTGGATTGCTAGGCTT-GAGAAGAGATGAAGGACGTGGCAAGCTGCGATAAGCCCGGGGTAGGCGC-ACGCAACCTTTGATCCCGGGATGTCCGAATGAGACCGTCGGAATTGAAGCATCTTAGTACGACGAGGAAAAGAAATCAATT-GAGA-TTTCCCAAGTAGTGGCGAACGAAAAGGAAA-CAGCCCAAACAGCTAAAA-TGTTCTGGAACACAGTGGGTGATACCCCCGTAAGCAAACCCGAGTAATTGTCCTTG---GCAGTGGGCAGTGAATACAGGTGAAAGT-AGCATCTGAGGCTAAATATATCTCAA-GACCGATAGTGCACT-AGTACCGTGAGGGAAAACTGAAAAGTACCCCG-GAAGGGGGCTG-AAAAGTGCATGAAACCTACTGGTTATCATGCGTTCCGTCTCGAAACACGGGCCAGGGAGCTTA-TTGTCATGACAA-GTCTAAGAAGGCGAAGGGAAACCGAG-TTCTCGCAAGTCAT-GACGGTAAGGCTAGAAGCCAGTCGATCTATTCCTGAGCAAGCTGAAGGTGGG-CGAAAGCCCGCTGGAAGGCTG--TAGCCGTACTAACGTGCAAATTGTTGGTGTGACTTGGGAATAGGGGACAAGATCCAATCTAGACTGG-CGATCGCTAGTTCCAACCGAAGCGTCTCGCAGGGCGTCCTCTGTGGAGGTAGAG-CACTGATCGGGGGAAG-AAATTCCTCACCACCCCTTCAAACTCCGAAGG-AGACGGGTTCGTGTGACGTAAGGTTCAC-GACCGAAAG-GGGTTTAACCCAGACTGA-AGTTAAGGTCCCCAAATCTTTGCT-AAGTGTC--AAGCTTAAGGGCGTGTTCATGCCAAGACAGCAGGGAGGTAAGCTCAGAAGCAGCTA-TCCTTTAAAAAGTGTGTAACAACTTACCTGCC----AAGTGTGGGCGCCCCAAAAATGGAC-GGGGCTAAAGTAAAGTACCGATACTTTAGGTAGGTTG-GCGTAGTG-ATTGGGCCGAAGCA-GGGCATTGATGTCCTGTGGAGCAGATCCTGGTGGCAGTA-ACAGCA-TAGTAGAGTGAGAACCTCTACCACC-GCAAGCGC-AAGGGTTTCCA-GGCAATGCGCTATCAGCCTGGAGTTAGTCGATC--CTAAGAATTACCG--AAAGGGAAACTGGTTAATATTCCAGTACCTACTTCTGGATAG-GGGAGTGTCGTATGACGAGAACCGATT-TGAAATCCCGGAGACCATGAAACGTACCGAGAACCGACACAGGTGCGC-TGGCTTAGAA-AGCTAAGGTGCTACGGGTATACCGTATGGCGAGGGAATTCGGCAAATTAGTCCTGTAGCTTCGGTATAAGGGATGCCGTAGGTTGCAATGACTAGGGGGTTCCGACTGTTTAATAAAAACACAGGCGACTGCTAGTCCG-AAAGGATTTGTATAGTCGCTGAATCCTGGCCGGTGCAGGTACCTAAAACTTGGGTTCAAAAGGGCCTGTTAACGCCGGGAGTAACTCTGACTCTCTTAAGGTAGCCAAATGCCTTGTCGGGTAAGTTCCGACGCGCATGAATGGAACAACGAGAGCCCCACTGTCCCCGCCTACAACCCGGTGAAGCCACATAAGGTGGACGAACAGTCCATCATCTTCCATCGGGGAGAGAAGACCCCGTGGAGTTTTACTGCAGCTTGTGCTTGGTATGGATTACATAGTGTATCTGGTAGCTATGCCTGAGAAGCGACGATGTAACACCAGATAACAGGTGCAGGTGGGCAGTTCGGCTGGGGCGGCACCCCTTTGAAAAGATATCAAAGGGGCCCAAAGTTCAGTTCAAACGGGACAGAAATCCGTTGATGAGGG-CAAAGCCAAAAACTGGACTGACTGGATTTCCAAACGCACGGAATTCAGAGACGAAAGTCTGGCTTAGCGATCCTTCGTGT--GCCCACTATTGGGGCCCGGAGGTGACAGA--AAAATTACCCCAGGGATAACAGGCTCGTCGCGGGCGAGAG-CTCCTATCGACCCCGCGGTTTGGTACCTCGATGTCGGCTTTTCCTATCCTGGCTCTGCAGCAGGGGCCAAGGGTGAGGCTGCTCGCCTATTAAAAGGAAACATGAGCTGGGTTTAGACCGTCGTGAGACAGGTCGGTCTCTGCCTGATGGAAGCGC--GGCTGTCTGAGGGGAAGTTGCTCCTAGTACGAGAGGAACAGAGCAACGTGGCCACTGGTTTACCGGTTGTCGGCA--GGCCGGGCAGCTAAGCCGTTTGGAT-TAAGTGCTGAAAGCATCTAAGCACGAACTCCATCCCGAG-ACAAGACAGCAAGGTTCGCAGAAGAAGACTGCGTTGATAGAATGGATGTGTAAG-TGGTGAGCATGCCATTACTAA
;
END;

BEGIN TREES;
      TITLE Archaea_protein;
      LINK TAXA = Taxa1;
         TRANSLATE
            1    Archaeoglobus_fulgidus_strain_DSM_4304,
            2    Methanothermobacter_thermautotrophicus_str._delta_h,
            3    Aeropyrum_pernix_K1,
            4    Methanocaldococcus_jannaschii_DSM_2661,
            5    Staphylothermus_marinus_F1,
            6    Pyrobaculum_arsenaticum_DSM,
            7    Halobacterium_salinarium_R1,
            8    Methanosaeta_thermophila_strain_PT,
            9    Haloarcula_marismortui_strain_ATCC_43049,
            10   Methanobrevibacter_smithii_ATCC_35061,
            11   Thermofilum_pendens_strain_Hrk_5,
            12   'Caldivirga maquilingensis IC-167',
            13   Thermoproteus_neutrophilus_V24Sta,
            14   Methanosarcina_barkeri_str._fusaro,
            15   'Ignicoccus hospitalis KIN4/I',
            16   Thermococcus_kodakarensis_Kod1,
            17   Methanopyrus_kandleri_Av19,
            18   Methanococcoides_burtonii_DSM_6242,
            19   Thermoplasma_volcanium_GSS1,
            20   Candidatus_Korarchaeum,
            21   'Methanospirillum hungatei JF-1',
            22   Methanocorpusculum_labreanum_Z,
            23   Pyrococcus_abyssi_GE5,
            24   Picrophilus_torridus_DSM_9790,
            25   Nitrosopumilus_maritimus_SCM1,
            26   Cenarchaeum_symbiosum,
            27   Desulfurococcus_kamchatkensis,
            28   Metallosphaera_sedula_DSM_5348,
            29   Halorubrum_lacusprofundi_ATCC_49239,
            30   Methanococcus_maripaludis_S2,
            31   Sulfolobus_acidocaldarius_DSM_639,
            32   Methanococcus_voltae_A3,
            33   Nanoarchaeum_equitans,
            34   Pseudomonas_entomophila,
            35   Thermotoga_maritima,
            36   Aquifex_aeolicus,
            37   Agrobacterium_tumefaciens,
            38   Escherichia_coli,
            39   Bacillus_subtilis,
            40   Thermus_thermophilus,
            41   Anaeromyxobacter_dehalogenans,
            42   Mycobacterium_tuberculosis,
            43   Cytophaga_hutchinsonii,
            44   Uncultured_crenarchaeote_74A4,
            45   'Uncultured marine crenarchaeote KM3-34-D9';
      TREE PAUP_1 = [&R] (((36:1371.0,(35:1253.0,40:1349.0):794.0):840.0,(43:1742.0,(39:1397.0,(42:1553.0,(41:1277.0,(37:1361.0,(34:1002.0,38:1096.0):1021.0):807.0):846.0):630.0):667.0):900.0):1306.5,((33:2104.0,(20:2140.0,((11:1681.0,(12:1520.0,(6:475.0,13:482.0):1161.0):1195.0):745.0,((28:1193.0,31:1119.0):1149.0,((3:1595.0,15:1458.0):721.0,(5:893.0,27:1188.0):783.0):643.0):792.0):984.0):811.0):627.0,((17:1659.0,(26:928.0,(25:39.0,(44:0.0,45:0.0):76.0):909.0):2212.0):832.0,((19:1155.0,24:1202.0):1693.0,(((16:569.0,23:493.0):1163.0,((2:956.0,10:1212.0):1153.0,(4:1006.0,(30:641.0,32:720.0):980.0):1226.0):726.0):571.0,(1:1669.0,((7:779.0,(9:824.0,29:883.0):420.0):1457.0,((21:1376.0,22:1344.0):1150.0,(8:1395.0,(14:1012.0,18:979.0):908.0):713.0):653.0):1027.0):940.0):612.0):826.0):805.0):1306.5);



END;
BEGIN TREES;
      TITLE Archaea_rRNA;
      LINK TAXA = Taxa2;
         TRANSLATE
            1    'Uncultured marine crenarchaeote KM3-34-D9',
            2    Cenarchaeum_symbiosum,
            3    Uncultured_crenarchaeote_74A4,
            4    Nitrosopumilus_maritimus_SCM1,
            5    Picrophilus_torridus_DSM9790,
            6    Thermoplasma_volcanium_GSS1,
            7    Halorubrum_lacusprofundi_ATCC_49239,
            8    Haloarcula_marismortui_ATCC_43049,
            9    Halobacterium_salinarium_R1,
            10   Methanosaeta_thermophila_PT,
            11   Methanosarcina_barkeri_str._fusaro,
            12   Methanococcoides_burtonii_DSM_6242,
            13   'Methanospirillum hungatei JF-1',
            14   Methanocorpusculum_labreanum_Z,
            15   Candidatus_Korarchaeum,
            16   Nanoarchaeum_equitans,
            17   Methanobrevibacter_smithii_ATCC_35061,
            18   Methanothermobacter_thermautotrophicus_str._delta_H,
            19   Aeropyrum_pernix_K1,
            20   'Ignicoccus hospitalis KIN4/I',
            21   Desulfurococcus_kamchatkensis,
            22   Staphylothermus_marinus_F1,
            23   Thermofilum_pendens_HRK_5,
            24   'Caldivirga maquilingensis IC-167',
            25   Thermoproteus_neutrophilus_V24Sta,
            26   Pyrobaculum_arsenaticum_DSM,
            27   Metallosphaera_sedula_DSM_5348,
            28   Sulfolobus_acidocaldarius_DSM_639,
            29   Methanopyrus_kandleri_AV19,
            30   Archaeoglobus_fulgidus_DSM_4304,
            31   Thermococcus_kodakarensis_Kod1,
            32   Pyrococcus_abyssi_GE5,
            33   Methanocaldococcus_jannaschii_DSM_2661,
            34   Methanococcus_maripaludis_s2,
            35   Methanococcus_voltae_A3,
            36   Cytophaga_hutchinsonii,
            37   Aquifex_aeolicus,
            38   Thermotoga_maritima,
            39   Thermus_thermophilus,
            40   Mycobacterium_tuberculosis,
            41   Bacillus_subtilis,
            42   Anaeromyxobacter_dehalogenans,
            43   Agrobacterium_tumefaciens,
            44   Escherichia_coli,
            45   Pseudomonas_entomophila;
      TREE PAUP_1 = [&R] ((37:0.153364,((38:0.114702,39:0.149186):0.013693,(36:0.258031,(40:0.19077,(41:0.126463,(42:0.119917,(43:0.134216,(44:0.08495,45:0.054425):0.060612):0.060803):0.047801):0.011041):0.01919):0.07639):0.071028):0.192716,(((30:0.140116,(16:0.267989,(29:0.10005,(31:0.026431,32:0.008165):0.06144):0.018082):0.012445):0.012061,(15:0.189393,((23:0.064507,(24:0.070196,(25:0.006954,26:0.006829):0.040432):0.042362):0.029489,((27:0.068837,28:0.057557):0.096668,(20:0.054844,(19:0.037396,(21:0.038702,22:0.016586):0.020912):0.006499):0.012943):0.025135):0.051702):0.055098):0.005758,((1:0.036669,(2:0.043509,(3:0.017977,4:0.005046):0.02101):0.018857):0.363994,((5:0.068662,6:0.052711):0.270332,(((17:0.095538,18:0.047107):0.123164,(33:0.041779,(34:0.013416,35:0.034511):0.103062):0.060741):0.020529,((9:0.044737,(7:0.083911,8:0.082856):0.039914):0.193532,((13:0.06004,14:0.109766):0.099943,(10:0.088336,(11:0.045959,12:0.044932):0.064867):0.02656):0.04107):0.116711):0.002742):0.020033):0.010878):0.192716);



END;