Protein Disulphide Isomerase and Neurodegeneration in Motor Neuron Disease [ 2011 - 2014 ]

Research Grant

Researchers: A/Pr Julie Atkin (Principal investigator) ,  Prof Malcolm Horne

Brief description Motor Neuron Disease (MND) patients currently face a bleak future. In the common global form of disease, the average length of survival after diagnosis is 31 months. Current therapies have at best a modest effect on the course of the disease with little or no benefit in terms of overall patient survival. We have new evidence that a protein called PDI can prevent the motor neuron cells from dying in MND and hence this may be a novel therapeutic target for both sporadic and familial forms of MND.

Funding Amount $AUD 318,517.71

Funding Scheme Project Grants

Notes Standard Project Grant