Enhancing innate immune responses to influenza in chronic obstructive pulmonary disease [ 2013 - 2015 ]

Research Grant

Researchers: Prof Peter Wark (Principal investigator) ,  Prof James Mahony ,  Prof Philip Hansbro

Brief description Infection with influenza is a serious health problem for all, but particularly those with chronic lung diseases such as chronic obstructive pulmonary disease (COPD). Current treatments are limited. We have previously shown that human COPD airway cells are more susceptible to infection with influenza and the virus is able to effectively block the early immune response. We propose to define the mechanism that underlie this and design novel inhibitors to enhance the early immune response of these cells and reduce the effects of infection.

Funding Amount $AUD 522,323.25

Funding Scheme Project Grants

Notes Standard Project Grant