Defective cell migration as a mechanism of dysregulated asthmatic airway repair [ 2013 - 2015 ]

Research Grant

Researchers: A/Pr Anthony Kicic (Principal investigator) ,  A/Pr Paul Rigby ,  Prof Darryl Knight ,  Prof Stephen Stick

Brief description Injury of the airway epithelium (cells lining the airways) is normally repaired by a process involving the deposition of specific proteins by the airway epithelial cells, promoting them to attach and migrate to cover the injury. These cells appear to be abnormal in asthmatics, in that they fail to repair. By studying specimens from healthy, allergic and asthmatic children we will determine the factors that influence the ability of these cells to repond to an injury in a normal manner specifically through their ability to migrate.

Funding Amount $AUD 616,712.86

Funding Scheme Project Grants

Notes Standard Project Grant