grant

Does nuclear reprogramming of granulocytes induce reversal of the hematopoiesis pathway. [ 2013 - 2015 ]

Also known as: Turning back the hematopoiesis pathway by cellular reprogramming.

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1051309]

Researchers: A/Pr Jose Polo (Principal investigator)

Brief description Generation of induced pluripotent stem cells has enormous therapeutic potential. However, it is unclear whether de-differentiation to pluripotency proceeds via a reversion of the same developmental pathway that gave rise to the cell type being reprogrammed. To answer this we will dissect the reprogramming process within the well defined hematopoietic system and assess the generation of hematopoietic precursor-like cells during reprogramming.

Funding Amount $AUD 461,805.78

Funding Scheme Project Grants

Notes New Investigator Grant

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