Harnessing lipid-reactive immunity to combat Mycobacterium tuberculosis infection [ 2013 - 2015 ]

Research Grant

Researchers: Prof Jamie Rossjohn (Principal investigator) ,  Dr Lucia Mori ,  Prof Dale Godfrey ,  Prof Gennaro De Libero

Brief description Critcial to the survival of Mycobacterium tuberculosis, the causative agent of tuberculosis (TB) is its unique waxy (lipid)-rich cell wall. This proposal aims to target components of its cell wall to devlop novel therapeutic strategies. Specifically, the Australian-Singapore alliance will examine how the immune system "sees" lipid based antigens from M. tuberculosis, and then will ultimately use this information towards the devlopment of novel lipid-based vaccines.

Funding Amount $AUD 341,458.53

Funding Scheme Targeted Calls

Notes A*STAR - Utilising Integrative Technologies to Combat Emerging Infectious Disease