Differential Changes in Cortical Tumour Necrosis Factor Signalling in Mood Disorders and Schizophrenia [ 2014 - 2016 ]

Research Grant

Researchers: Prof Brian Dean (Principal investigator) ,  A/Pr Elizabeth Scarr ,  Prof Ian Everall

Brief description Changes in inflammation-related pathways contribute to the symptoms of psychiatric disorders and tumour necrosis factor ? (TNF) is a protein central to regulating theses pathways. We have now shown that changes in pathways regulated by TNF are present in the brains of people with schizophrenia and mood disorders. This means that the symptoms experienced by those with the different disorders may be linked to differential changes in TNF-regulated pathways in the brain.

Funding Amount $AUD 642,078.71

Funding Scheme Project Grants

Notes Standard Project Grant