Investigating the therapeutic potential of FTY720 for Human African Trypanosomiasis [ 2014 - 2017 ]

Research Grant

Researchers: Prof Vicky Avery (Principal investigator) ,  Dr Graeme Stevenson ,  Prof Susan Charman

Brief description FTY720, is a drug currently used to treat multiple sclerosis, which we have shown is also be able to kill the parasite responsible for African sleeping sickness, Trypanosomes. We aim to identify the target the drug acts on in the parasite to have its affect. Our objective is to improve the activity further by chemical modification to produce a potent, orally available and well characterised, non-toxic drug suitable for preclinical development.

Funding Amount $AUD 653,736.47

Funding Scheme Project Grants

Notes Standard Project Grant