grant

Discovery and development of better pain treatments [ 2015 - 2019 ]

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1072113]

Researchers: Prof Richard Lewis (Principal investigator) ,  Prof David Adams Prof Glenn King Prof Macdonald Christie Prof Paul Alewood

Brief description Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clinical potential.

Funding Amount $AUD 9,613,849.73

Funding Scheme Program Grants

Notes Program Grant

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