Drug targeting to sites of lymph-adipose interaction to transform the treatment of disease [ 2016 - 2018 ]

Research Grant

Researchers: Dr Natalie Trevaskis (Principal investigator) ,  Dr Darren Creek ,  Prof Christopher Porter ,  Prof Matthew Watt

Brief description Insulin resistance (IR) underpins the development of inadequately treated heart and metabolic diseases such as type 2 diabetes. Recently we demonstrated that high fat diets promote increased leakage of fluid from lymph vessels to abdominal fat, and that increased access of lymph fluid to fat stimulates fat expansion and changes in fat function that promote IR. This project seeks to optimise novel drug delivery strategies that target lymph and fat and more effectively treat IR.

Funding Amount $AUD 529,827.07

Funding Scheme Project Grants

Notes Standard Project Grant