Glycan-glycan interactions between bacterial pathogens and host cells: A novel mechanism of bacterial adherence, a new opportunity for strategies to treat and prevent disease and a new paradigm in interactions between macromolecules. [ 2016 - 2019 ]

Research Grant

Researchers: Prof Michael Jennings (Principal investigator) ,  A/Pr Renato Morona ,  Dr Christopher Day

Brief description Cell surface carbohydrates are ubiquitous throughout nature. Human cell surface carbohydrates are specifically targeted by microbial proteins. These interactions are crucial in causing disease. We have recently shown that the carbohydrates on our cells and those on pathogenic bacteria can interact with one another. Understanding the nature and role of these newly discovered interactions may lead to strategies to block them via new drugs and vaccines.

Funding Amount $AUD 1,093,400.51

Funding Scheme Project Grants

Notes Standard Project Grant