Defining the molecular regulators of apoptotic cell disassembly and their role in cell clearance and lupus-like autoimmune disease [ 2018 - 2020 ]

Research Grant

Researchers: Dr Ivan Poon (Principal investigator) ,  Dr Edwin Hawkins ,  Dr Mark Hulett

Brief description In humans, billions of cells will die daily as part of normal turnover in various organs. It is vital that dying cells are rapidly removed as their accumulation has been linked to autoimmunity and inflammation. To aid efficient removal of dead cells, dying cells can disassemble into smaller fragments for neighbouring cells to engulf. We aim to understand the machinery that controls how dying cells can disassemble into smaller pieces and their function in cell clearance and autoimmunity.

Funding Amount $AUD 784,681.86

Funding Scheme Project Grants

Notes Standard Project Grant