Hijacking a death switch in pancreatic and lung cancer cells to develop a novel therapy [ 1/1/2021 - 12/31/2023 ]

Research Grant

Brief description Pancreatic (PC) and lung (LC) cancer have a high mortality rate and poor response to current treatments. We have identified a protein whose inhibition in both PC and LC cells sensitises them to a cancer-cell specific therapy called TRAIL and switches signals that normally promote tumour growth into tumour death signals. This project aims to develop a novel therapeutic that inhibits our target and delivers TRAIL to PC and LC tumours, and could potentially improve survival for PC and LC patients.

Funding Amount $738,947

Funding Scheme Ideas Grants

Chief Investigator A/Pr Phoebe Phillips

Notes Ideas Grants