ePubs

The open archive for STFC research publications

Full Record Details

Persistent URL	http://purl.org/net/epubs/work/65212
Record Status	Checked
Record Id	65212
Title	Lyophilised protein dynamics: more than just methyls?
Contributors	MTF Telling (STFC Rutherford Appleton Lab.) (Pr.Au.), L Clifton (STFC Rutherford Appleton Lab.), S Howells (STFC Rutherford Appleton Lab.), B Frick, J Combet, V Garcia Sakai (STFC Rutherford Appleton Lab.)
Abstract	The movement of molecules on the fast pico- (ps) to nano- (ns) second time scale in proteins affects the slower, larger lengthscale dynamics involved in protein folding and biological function. As a result, detailed understanding of structure-dynamics-function relationships requires the use of theoretical models that incorporate the full dynamic complexity of a bio-material. To advance such models we have used neutrons to probe protein dynamics on the ps-ns timescale in a series of proteins: apoferritin (Apo), insulin (Ins), superoxide dismutase (SOD) and green fluorescent protein (GfP). Our results hint at a protein structure dependent dynamic landscape.
Organisation	ISIS , ISIS-ILL , STFC
Keywords
Funding Information
Related Research Object(s):
Licence Information:
Language	English (EN)

Type	Details	URI(s)	Local file(s)	Year
Report	ILL Annual Report 2012. 2012.			2012